Document QgO5gdaoQmp7ZamqkjRvLgvqE

. ri 'j A i & 5 5 - ' V -j - *; LEAD INDUSTRIES ASSOCIATION O CAST 4IM |T*(ir Niwmwir, nr. October 7, 19$9 l f a i> Krovrt j rn3C------------ To the Moabers of the Lead Zbdoatriea Associations Tcrsdnatlng sorles of publication daisy* quite beyond oar control, a coqO 1 nontary copy cf tha ntocmraos c? ms ms Hrorca comBcx hold In Chicago laat Horeefcer no* goes herewith to each indi vidual In oar nerbership who baa aakod to receive these boll#* tins. Additional copies to oar nenbert vill bo two dollars each, a flgure veil bale* thoir cost. Oar conference was without question the aost Snportant and authoritatiro on problem* of lead hygiene in asny years, and It Is hopod that the papers dellt o red by this outstanding . group of speakers vill have the attention they deserra. I i LIAD INDUSTRIES ASSOCIATION 60 (AST 42ND ITRfIT ) NSW YORK IT, N. Y. 36^ I- -O'! r ' VVY: 'T-. FOREWORD TW p*rpa* of th* L*ad KfftM CffrtK mnrtij la (IW Bttto Trim m to vmiUU* U *dir*l a**. fcyrtoouto and Intoreotod Uyia, to fra* *d < tl* fart* noirrraia# plumb**** whkh aaf--11* jiraMal lij wafipb *< Ita faaaatUo. natnl u4 cart. TW tola *t)*rt h arkim4 Mfflu amptr *rid*orod bjr tto caliber *f tk* irttoHlfi oa emrtoo* a*f*rU af toad pntocoln* whet (MtHUiWd th* fraiU af hdr nprrtort to th* pmma, by th* qwlitr of tMr prwMUitoa. by lia aHi* (arttripitto af im 1m* Uiaa forty todJeidaala to th# lUmnltai, u4 by tk* fort that mv Ihu -quarter af IW 140 (tkjtkUto lodaatrlaliata and 4k*ra pr*MBt took tk* trouble, la totter* arrittoo aoua after tk* rnfmac^ la *apr*M tbrir fetyorUttea cf kariay brra ladaM la what oo* rid Haw terari tot *f tk* toot rmp of ladaatrial kyffcaa ari arikal yaiiaail tkal I kata Mn amcaibtod to a too* Ua*.fl la taro, tto L*ad Iriotrto Aaaortotfew wain,aura thU opportoatty iftla to tkorh afl tkaoa who by ttotr paitlcipatioa oooared tka uccoi af tk* coafereoro. Tor tk* lalttol printed rarord w* or* indebted to the editor* and publisher of tka >oaraal Iad**trl*l Mdkio* and Burgny. Th* aaajar reeUtoo pr***pl*d wltkla tkea* cover* attcaU tk* editorial akiU of Mi** EHsabeth Obatei :"^pii!f5APLPiUl i^|UIi>^j 9p q o m re THUUOAY AnnNOON HUtOH <C**4 ttmutu n it i* nrt MMMMia or rumM fi XtWf*r4 T- MmUm. Sit), Co mMs * m /ftforfriof fx<--Ify. Lm A#*!--. .................. iVKf*<................ tmcvmum. Mbf Li Ho*Ok*. MJ), At W*m fraWiUi C*-Oos. OW|t, /UWM .................................... >.. ...............................................9 - i fMn C W*Wrt, LL, r-rf MWff. AferyAoW.. ....f MtrvwMi. U4 ky Ar^ktr i, JI>m, VI#* 4U Jtfolaoi /mmmv C*V**f< IVi^/UU, Jfn-- mOAY, HOVWOai 7. IfM MOfttftNO tmtON Owhua Cmtt M. WWW. SC-D, MmL _ - Li/ Imw mw Ctywf, A'r Vwi. ifX . m i)mi or h u im ak rwnairm m c w mm nnwH Am* M. Bc J>- 4mw ii* tffttmr / ttnwwtol '' '"fc: - ru Mm Wq W 5kW *# Wr**ro# W Mir MmMA, ItafoWiro, . |ftf)4i*4 ........................ '' muiwaw. fa4 hy J. Jtlla CVmIo , Jr, H.P, Amirt**! N/**m </ M*ln. JTU Mm Hvpktm &*ift / M*4rw*, JiIHmm?, JYoqHooA...>.44 . m* tmm w f>i tw mwin ua unwrwm rwo iw u iw h . SSfMVOB ^v Lx tt HiU*. M-D, Krtttrimg t*lirtU*y, C/oftrroity of Cio4o--N > < / NAi*m, CWItMlI, 04*o.. .. 44 .>v u*wuiinisnaBuiA)(imTMunwwipi> ' 1 - - ./S* . . H> a Wk. IU, ^ *]?-V. ihr MMti, OAw ................................................................................44 . -.t.v c MartMMN or so. mixes'* *r ml iw t Yi rtnn. M W Horriot f* lUt^, Ki), AmmOI* /'i^nrai.riw. JT4mI CWlk * JWonxAxrtt* CvfW U90p*ft, JfumUwHi............. ........II mm wm m a * umsttnu. iinwHifwi or ruTM mwa < ' . * uifutMi m aofoNMi ornMu nuam n nmy w im u m (ONIWIIM TMI ATMMTRDI . .`i' /. ' |Ufc*H A- XH***, SiD, tHriUr, iWfrH*# Lol*rolory. Pa<Mni|p / CMmit Cotir## / H*4Mwa CMnMi, 041*........................... 41 : IUMCHCOM SCSStON - . ^-V - ;`-^V jug*; YWuta L. AIp mii, M.D, IfraftA Oir<M twM, Lor 4Jaawf ItWiN/b L*Lnlr|il l* AJomoo, Nn t AnnNOON tnuoH ^ ' ; CliksM - N*sfr4 Bo4Hb . - -`VV*'' MsctiosMM or os. Kuos'* rAra, M bjr 0. Jkn Lotwr. MJ), JforfWaf (Mrwtor, J+nr* 4 LmmgMi* Aloof ! .49 SMNI tAA HNVMOM ..........................................................fl AtlNci XoaUr. U4 HrgWoo Cwfuion ...............M ' v'.-. * / :- 3 LEAD INDUSTRIES ASSOCIATION lAD HYOtENI CONKtMCi NmnU *-7. 19M THURSDAY MORNING SESSION Nonmlw , I9J INTlODUCnON .3 r IOMCT L OfOHLO Trrmw, Mufrin * * .33 Ladim and Goatferom: It U a pkaure to Loro tb* opportaalty of *poa*ertM mrrtinf that Include* uch * dUtinrubhed rotboria# of yu**U and from which ao much rood mo/ bo expected. Tb* caliber of thooo who h*t abroad to toko official port to tb* prufram. and of tbc*e who kart cocao to Uita and dimM with ti>no, mot cectaialy Indicate* a fruitful conference. For Ibooo of you who may not know too much about the toad WwtHw AMOcUtino, ! would Uk* to explain that It la a uoa-prodt ornulutla of n c m ?0 laod-minlns, taohmf and retain*. and manwfactwrinf companion. While wo have many function*. lorlodlnf h Wi proowtloa, rwwcK technical aonrietk fcoootnlc aorrico and tb* like, L.IJL loetr afo rocofaUod It* r**poo*ibility ts th* Odd of Wad tifrine. ta tb* 30 year* of our #*l*t*oeo, wo Karo sponsored cm* iderabte research la tbl* field, and wo are now ratberod at or third Cfl#* feronco of thU typo. Xort than a decade ayo, thi* phaao of oar work waa put under Manfred Bowdltch** full-tiro* direction. Now, to fH lbo Important part of thU meetinf under way without further ado, I want to introduce your official wekoroer, Mr. Folia Edfar Worrnaf, vie* provident of L.I.A. and of th* St Joaeph Lewd Company. Load hyrieoe ha* toof been a *ub)ect to whkh be hat riren much intenwled attention. )U was tb# Aret Mcrrtary of L-I.A- and bold tb* position for o**riy 13 year*, whoa bo Wft ta join hi* prevent company. 8ttb**qu*ntly, k* wu provident of LJX for throe year*. H* ha* *Uo mad* ymt contribution* throurh public **nrk*. harlot oarlier thU year completed fire year* a* amlatant arcrotary for mineral roaourcea of tb* U. 8. Deportment of tb* Interior. Mr. Wormier. I" . i'ii1* y:' f 1 nw*1" piyguumw,. !.w. u j .u j j WEICOM1 uxr i o o a i w o i mj u Vww /Vr*W<l, /.*W t'We Fv*ed*a 5i (W^if. ,Vrv )'#*, AT. F. I am Wift4 to c*prwnt the prwldrtl of thr Lead Irvduflriss A**<*istii. Mr. John D. EradVy, h\ unfortunately, cannot be with m tod*?. I m tar* he mM with to tito4 yam a m-mt (crdiil Welcome to Qktfn, and to esprsea the hope that y*ar deliberations w0 result la mutual eachangv of view*. beneficial twt only lo our industry but to naaklni It 40*4*1 M*ta {uMlbW that fMn bar* elapsed iia<* lb* flnt crriferwic* of phy- ifUai end surge**.* of member crenpsnlee of the Lead Industrie* AasorUlVoc vu b>d b*r* in Chicago at the Palmer House, U atom* like yesterday to mo. Some of you (a Ikli room to- da/ att*o4*4 Uit Mwioo. end you will mom- ber bcw interesting it we* to li*ten to Dr. Joseph Aub end Dr. Falfhalt, who bod done so much ptaeere work in thr held of Wwd poW-ailng. Vcr afo, t frtt (Kit tlx Lred liduHrifi AworUtioa rould |u<tif]r it* existence *oi*l)r (4 Um ground of lb* opportunity it had to wt to Um field at U4 hygieo*. so tlul thr sort*! cvuld be used properly end Inlrtligrotiy. end no that. Knr'rr it crested a haserd In dustrially or publicly, thr proper rwttmU rvuU tr introduced. I bmt rhuipd my rim, I think you should kjv/w that aa thr work of thr Association ha* bectme kflcra It bar re ceived international rer*>g'ni!ico and rrprwniU* tlt. It also W thr beweftt of Manfred Bow* ditch4* great e*perieoce and knowWdre la thla important area. I think r ran all airrrr that thr Lead Industries Association. and thr peo ple behind it, deuerve commendation for thr public-spirited and frank approach they harr fi to thr Wad problem. When all U raid and done, what thr Industrie* want la thr truth. They ran then govern themacteer ac cordingly. Thanka tr much brilliant wort in medicine, participated in by many of yon in my audience, thr truth, pleasant or unpleasant, U certainly what they have gotten, 1 am turn they will also yet tt from this meeting. It ha* always aeemrd to me that there D nr reason why a wonderful metal *o<h aa Wad, be stowed upoa ua by a bouMJfu) nature, rani be need safely and beneficially by alt of ua. It w t *U4 be diAruh tr conceive at aa economy where tMa indtspmaatJe metal Im Wager war ivaikbi* tr w. It hae m many everyday area that we take for granted, especially in ddrlng our autcmobiUe. Although my Incumbency In Washington kept me away from ota lifting thr aterdy pcv.grma that thr medical peofereior w*a making ir studying the Wad haiarda and leUtrd problem*, 1 am aurr we *Q mxgniie that many aardiral reeeanh ds-rvWpmrnta ilarv cor first conference hat * firm i aa assurance that err previously did ncd poMfwk So doubt three U atilt a lot rf rdurati<ma) work that har tr be dorr where Ignorance about Wrd* properties re rara atil pcwaila. But I did not error Were tr take thr Ume at thla important meeting any lorftf than tr ttpreae my own personal delight at bring bare m a a interested listener. I am Mtre that out ef thla r>r.fcrroce much good wlQ come, rod I wish you t new take pleasure In turning thU mtrilag over tr our chairman, Mr. BowdHch. err Art wot MAwrto nowprmt: Thr first ef our technical paper* wit) be by Dr. Cbtac U, Belknap, who ha* been connected with the storage battery industry longer than I can remember. pc ULKKar: ft in a pWaeort tr be with you again. It arems Just yewterday that we had thr ctwifermcr aymtwaium her# that took place tea year* ago. | would aUo like to any that although it doesn't appear on thr program, thr co-author of this paper is my son. who is hree with me today. Hr was associated with me for a ten* Idemble time In some ef this work and la now doing research In hematology, and teaching at thr University of Wisconsin. CUNtCAl CONTROl Of HEAITH IN THE STORAOI BATTERY INDUSTRY By IUTON U MVKMAF, M.O. Wbrt the ser.ief author was ftrel as rocnultant medical director of a largt battery company 1a 193a, ths grfversl manager Asked that mar.fi getoert 1+ fidvled OSve A month regarding the level of lead absorptron t the worker* II* also *`4. * Miki your rcrommmda- tkc.s id-wi -- film fit the stars for what you think *txmU to doe* to prevent lewd absorption but dc*i be surprised if don't put into effect at) lb* rormnfivrtKUtloAfi fit tort. Hcwntf, hoop fT*f ai*d gradually We will put them Into Wft w mm fij we cfiA w-ock Umq Into er frodurikA schedule*." Over the Um company And their lc.urance carrier have bt-- slowly but failhfafly iraprceieg proteetivo m- gineeriag ventilsUua designed to collect lead dart fit tU source. The company U Globe L'nloc, find the IfiMirtM urritf, Employer* Mutual of Wfittsfin. Both by frrqvmt plmt toon And (Mr torro IaUo o with physical nod laboratory rxamlnntlesM of lho a m. lho Medical Department hu bm tU* to point out definite point* At *vrk places where production wjulfenet *fii defective of ifLAdequal* regarding du*t Collwrtion, thus caus ing Increased Uod Absorption. Howrtff, with the iocrwlfif ifnd of modern mnbiMi, the potential M hfiffird h* boon multiplied rapidly. In moot iftfUnm wo have aB fett thit we vert kvrbbf m n tons -- foreman. auperinleodent. engineers. general manager and Iho lead-exposed workmen tbmMltr*, ao w o O a i the Mfdkil Dt- f*rtsnent -- In a determined effort to reduce bn* Bun lend fitoorptim as rapidly w practical The rmh of ikli teamwork U demonstrated by the rodvetkm of the rate of disabling lend intoxication from 20% In 1929 to t% or S% vitkla the krtt tit yean, and by the fact that thereafter disabling tend intoxication or trtM tend poisoning ha* averaged only one every other year, and none at ait the last two yean. All of thane c a m* were of the simple lend colic type and were never complicated with lead palsy or encephalopathy. (Figure 1) The year 1929 was known to soms of you si the greet financial crash. That was the year lost Ufoce I came to the company when there was the greatest incidence of disabling trad in* toxic si ton. Then It tapered off fairly rapidly when we sorted out our most heavily exposed workers and had a very cooperative engineering group working to reduce the lead exposure. There was a tuny perhd, from 1934 to 1940, when we had only one case of lead Intoxication. Again la 1944, there was a peak of live case#. This w as the time when automobile produc tion the country over was at its peak, and we Vrfi working In many ln**srv<ce 10 hours a day. six days a week. all contributing to increased tend exposure and absorption. When you have 1c m time to get rid of lead, if there is any break in technique la protection, you will Immediately aee the re*pooae In In creased lewd ab*orptk>a. For the last 22 years, the Medical Department has always been able to am management and the torn themaeires of heavy lead absorption, so that the torn could bo ftwrtfd pending a miiKtkm of lewd exptwure. In the eight year* from 1934 to 1944, and the fire years from 1M4 to 194A, there were no eases at aB. ( Figure 1 > In aB c am* of actual disabling lead pniwjfting there has bem engineering break down or delayed repair of faulty engineer* lag ventilation equipment, or even carsUvO' news of suave of the men U using the respira tor*. Kccq y yr u* Concurrently with tb Medical Department'! warnings gained from qualitative testa, the en gineering protection has been In 4 process of eleady Improvement This has Included the In* stalUtioo of a very effective dust disposal eye* tem with a bag House used on the machine! which give off the |re*tewl amount of lead duet In addition to the cyclone system collertlng lead dust at other point* of Its evolution. During the process of Improving the engineering control, no m not to Interfere with the neraasary pro* ductlon, certain men have been equipped with respirators, both the regular face masks (Buroan of Mines Approved) as well as positive pressure airline masks in certain case*. Current samples show that all are now under the safe limit of T j>s"ww, -r w BKIJCNAF t mg prr JO cubic frw^cnt except tv> InataAc** of S3 ir.g And on* of 3.33 mg cool/a#ting the high lr\cU frwn 1144 to 19J4 wher# Air aafr.jJ** In aevm ln#tancea varied from ? mg to IS mg. (Figure 3) 0\rr th* pa*t 33 year*. th* wording enrlrao- mriit ha* from uo<otrc lied W*d ** poaur* is th* totally unprotected work of hand mixing and band (oating. on through th* ua* vt th* ewrty Automatic machine* which were not well eihaurtrd. And ftr-al!/ up to tha modem mixing. parting and AA*m>Uy, high-yruduction machine* wber* a frnt amouat of engineering ventilation equipment ha* bw) built Into lb* machine* fn** th* moment of their finl feeigw. For 23 year* w* hat* had th* opportunity to tody fiiolcaJl/ a aiowly changing group of W to 100 mm *ho hot* Lem npoMd to th# inhaia- tioo of hod la varying concentration* la atorag* battery manufacture. While thcr* ha* lm change of prraonne), our tabor turnover ha* been vary amalt, ao that th* majority of our mm hat* bewn working In thU aam* plant from At* to 90 year*. From th* beginning, our work la th* dlagnoalt of lead absorption ha* b**n baa*d on th* pioneering work of Aub, Fair hall, Minot, Rrxnlkoff, and A Ur* Hamilton.1 In thla aerlea of rate* w* hat* depended rhlefly ujion th* careful clinical examination of each worker at frequent Interval* of from two to four weeks, depending upon th* concentralloa of hla lead ftp<*ur*. Th* phyalclana have been trained In th* general field of diagnostic medl* cln*. Thla ha* Included ualng th* medical akilla of hUtory. phyalcat examination Including a eeA/rk for lead Itn* of th* gum* uruWr a tens Figur* fi, ot>* r> at ico of th* tJ*<d prtwaur* and the trmgth of Iht *xtrr.ace muwlea, a* w*fl u laboratory *twd<* Including hemoglobin, oum* ber of etJppled red c*P* per 30 high power of] Imn*r>k> field*, a rrxjtin* writ.*. and gualitatlvo te*t* of urine for repfoyorphyria. la tariuua learned cirri**, 1 her* Leon arm* what h'ekrd when phyalciana hat* a*M that there may Dot t any aurh thing a a lead lift* Imyfy beraw** they hare sever mu IL If yog will 1A at Lh# upper left Inrleor area la Figure t, th* left rvwtraJ iacieor, opfewJU th* Lax* of th# tooth, you wifi ae* th* "W4" lim. la th* gum. not oa the teeth, there la a row of doU or trial* mark* which mean* a deposit probably of lead aulphlde la the guma. ThU will not wa*h otf. and It wiB ooly dluppar wbea there la a reduced amount of concentration of lead vitkii the organiem. I know la the part that Df. Ab weed la have kU rraideala take a amafi Mrtka *f thla gum line and look at It under the mlrruaropa, thea am* ran are a LUck depoait directly utader the laaroaa. 5o her* U the furyiai "lead lia#" that waa deaenbed over 100 year* ago Mon the Royal Variety. and knows alt^e a* the Burtoclaa Un*. InruSentAHy, at) of thoa* taaea wer* chaaa whera lead aalta had bees seed aa internal medication. ac*irrrtt|atlfa*Pjr, la the treatment f patieata la the hcapUal at that Ham. We have changed our therapy wawihat and do nut prescribe Wad latemaHy aaj aaor*. bat the Wad bn* from occupational expownr* oaieta aa described originally by Dr. Burton. I spent a little time oa that became there ha* been mm argument aa to whether then la auch a thing aa a Wad Uoe. In addition to th* clinical examination of th* patient and th* barn-tin* laboratory atodle* ll#ted t bor*. (her* ha* been clinical avaluatlou of the work place la regard to Wad dual lakala* tW la the atorag* battery plant by th* aam* phyaieiaa ThU Involve* tudy and corrWotkm of the worker*a actual operation oa hla job, to> gether with the phyalrlan'a bnowWdgt of hla general phyalraJ condition and perweud habits, along with a medical maluatloa of the t*v*4 of hW lead aWrptlon. Whenever a man homed danger algnal* Indicating the protabUity of aa tmiwndlng diAahling Wad Intoxication, he woe either moved or given a jxwiMv* pr***ur* air(In* respirator while engineering protection waa bring Installed or Improved. In 19Id, In two c*a*o of threatened acuta Wad Intoxication, axported time off from work owing to lewd pol*<mlaf therapy waa reduced from a porlod of several week* to a few daya by a ccmrae of intravenoue Calcium KDTA under a hoapltal r*glm* aa do- t-Jgiii.. Ai- JMWJi . iBSfciisZf* v>- / f* ft \ 1 O KtZtLTff IS TUF. iTt>RACE MT7ty HAP AJtOtrtio* cwy **4 0*A**h w . MS t *-n ini C*- ,w 1 1 t 4 1 a t 9 9 M 1< It It M it ft Im .*4it fistw Sv 94m 9 94m 9 9 9 1+ Wek C*S* W 14 ? 14 If > V It 1? 4 * M I a M n ( -m l>J tin hi Hi ti IIS i*J us lu IK IU in at ii tty H. 99 U *4 M U n n m n 79 St Cl IS 7 u 4J 41 H 41 w 41 99 44 S 4* t m 41 99 04 H*oArm Ah 4 I 1 1 I 4 4 > 4 4 t 4 > P*#e4rfe fiv U-m >v Ws V *. >. >*i- tm J1 4M St* OSf 9M DM Ml KM Jl 104 IN art IN tea IN MS H H4 IN 2<m IN im Srf m Cl? n S14 N sit fik twl unlock* -* - 4111 Itlt son SiM Sen SMI sort 4S04 stif sort *S* SIM 4 OH AM Sift Ok fk Air Air A* 10*4. im w. --** - .-**^~* -- lift ?J9 IN ?IJ4 SM fSl SJS tit SIS A4 Si SJ4 ly? 14t SJS tic? IN tict Sit 104 Sf? IJI SJS IV) ISI IJ4 SM If) SM 70* AS,-Hi H --m wm*s lJM| WfX I tilfd elsewhere* No ml Cakitu CDTA kM nn bftfl firm to ohm is this pUnt Y*n lea, rntWtWHi f 21 kwif urine* for quantitslh* ksd del*causation u das# ororjr few moflUu to supplement the rpit*4 riinki) rtaminolkn sod the simple qualitative teste which vrrt prffonMd rwry two mb. ThU tu rtrrird put for IS ;rr*, from 1M2 to IS47. ll</wror, It m found Uut Us Information rained by thU more refined toot of quantitative lead ta Uw urine w of so nof* pnrtkiJ value Ihm tho simpler to*t*. la fort. It did sot nn**f a i helpful In our personal study of iHo Individual irorfcer so did tho orlfiM) trots of lend lino of rum*, strrnfth of wrists, hemoftobln, stippled ioC uunt *nd. Utrr. urino for porphyria. Thooyh tho Medka) IVr>sr!mmt hsd often boro eryed to substitute quantitative otudlra of tho urino for losd ti s MTronlnf tost in place of tho lend lino and stippled coil study, wo became convinced that quantitative lead Is tho urino stud/ alen* u not safe. Thoroforoi, study of tho losd IIm, hemoyloMn snd stippled cell counts was con tinued throughout tho entire 2t ye*r of chiefly mnlirsl control of Irsd absorption is tho worker. Routine nomination of urine for qualitative tost fur roproporphyrinuria has also boos dofto for th psat nino years * n helpful adjunct lead' Iny to a dfajrnosla of trad Absorption. Wo stilt believe it has basic Implication* in tho motah* oilws sf ldtaj A msUr of osthoro sad clinkaJ workers la tho field hot* noted that qual itative porphyria toots are of distinct value Is tuyyestifcf lead abeorplkm tm-ioninf positive be fore etJppled crIW appear.*-**** Itseeotly this whole question of Irsd abuorptien asd inloikitloA has beeo hero reevaluated no measured by both qualitative and quantitative laboratory determinations. This Intensive study involved IS mm. two of whom had worked for threo years, five for *i years, two for II to 12 years and sit from 20 to 22 yours. They had all bees rtposed to henry Wad Inhalation from time to time. It was already known that they had definite evidence of lead absorption be cause of the simple though frequent serial otudlos of history, physical etamlnalJon, and quail* tativo blood and urino studies. Threo mow now have faint but definite lead lines and tho majority have had on r*Th*><-r stippled rrU counts of from 10 to tt per M oil immersion fields. Those If mm were chosen before there was any knowledge of their oaart b)<x>d or urine quantitative value# for lend. The clinical and qualitative loots alone had already shown that lead absorption was quite high and that thme particular men needed t# bo wolchod closely. (Figure I) You will am on tho loft tho column for quail* tativo tests, and on tho right thoee for quaatlU* tivs toots. iij u i -s-mejiuii ij- r irirmui i|~~nnTTr.n j. ; mi 1 1 n | --" ...........-- '* *.,Vv :; i- iv | Wiiiiiil :- > i ;. v 10 BEUkNAf In regard to M atpeauro, a* i m Vj t air la figure X. bin hlgtuot bad otpunur* wan imIt mi, tb* hut nlom of tttni m Dm rifkl I. but awn rereeilly only 0 M He I* working mprraenU the limit capceure covering a ia chargt of auloenatlc canting where ordinarily ptrtfl^ of oil uit|m from ihtl to 1PM. I on we think them In eery llllb etponaru. We know run that you wlU no* I bare bon bom oomt fnlrtjr that whra tb# bad otld* coolamlnatad acrap high bvelr Tbli Is tbo amount of bad to tbo jwrli nerve over from th* panting lino, they am olr por 10 cubic meter*. and tf yew >Ub to m- dumped on a bell and go back Into tbo pot duc# I to value* por cm* ruble motor, foot mom We bam bad eucilon at tb* print of dumping, tbo doc Imo] point to tbo bit. but are now placing tarUoa around tb* ceemyor Tbo column next to tbo right In tbo moot ro* bril lUelf. not olr analynln, and you ooo It boo drayyad There wan at rilnlcal evidence that nortoon, aharpiy. Thin woo dooo la UK He-trover, la Irrwveralbb damat* bad bora doevn to the** moo " thmo lootoorm, wo or* all nllghtly owe tbo by thin degree of bod abaorptloa. If tt bod bom permitted lent cf 10 mo por 10 nUc meter*, felt Uul l ran*lent period* of Increannd bod ab* aamety. U fox and U1 mg. oeydioa oer# likely to can** onrioon organic Throe tom. an I ham oold brfoeo, am onwarod dinuxe wttb reeldual*, w* would not bam ro ' areordlor to dnnoilei nomtrotita of bad lled entirety on tbo more tonQy avallabl* teota to tbo arino. That In porbapo the moot inpoetoot which am a nveaeure of tb* ladiriduaT* body ro cwrreintioa. t would ilk* to potat out that, la od lew to bod. Wo wlabod topoctally to detmnlo* tboao It cneon when wo were trying to He tf whether evidence af Impendlag bod Intoxication tbo quoatltotim bad pore ao aay tafarmotioa rmid be more abarply predicted by quaatilatim which tbo qualitative tento did oat gtvu. nocb toot* of arino and blood bad, ntbor than by tb* Informatitn to aotrd la oaly ooo too, aambo* man oeity obtainable leetn that vn* bad boot eiibL Thin wan a mao who wan ooco heartIp uaiag far many year*. rapewnd to tblo cuwrentrailca of w*0 over tl *1*1 dona thin rrreot work on a amall group v me, tboarb Bow on!/ U mg per U ewbb anlin of bod ubeorptico raaeo fman tb* ntorag* battary of air. II* wan uaing aa airtla* mnpfrator Kot ladantry nbow an regard# tb* an* of qaalltativo d of tbo tiovo. Them warn certain pnrtodn wbna tret* coot ranting tb* am af coavpUented quaati- j bn bad to tab* It oS for marbla* repair*. H* latlve te-t# a**d la a anarch far aariy can** af never bowed a bad IIa*, lit. lacMontaQy, In nlgnllraat l*od atworptloaT By rignlllcaat ia the maa that baa worked S year* and it aew meoat can** who** dbabUag bad latoxlcotiaa la *1* tbo ptak" phyriraHy. bkoty to ocrar la aa* I* Ur** Math* If a* ia* If* bad only four atlpglod nth, tautlotli aeedieto rifort I* mad* to radar* tb* bod ** won N', nr IX-d ta, aad be nearly ahray* ban ponerro. Tkle coa b* doa* aitbar by awe-lag tb* bed a 4 plan porphyria teat la the aria*. work** a* by laelelenc* oa tb* aa* of approprtal* Yoa M*. la ad tiwtance* otrtpl non, that tboao rvegdralom while defect* la mechanical proton- canoo nbow n threw to four phea porphyria. Um oqeipmmt am bring corrortod. la tblo cane. Bamher tight, tbo lewd line level la In IX of IX men them wan rridmr* of baavy ..? the aria* I* -tf and la tbo blood j MI Thin to over bod absorption by both type* of IroU. la tody the no-rolled nofn lrr*i of bad la tbo Brian tf -It: erne ran* (number right la Flfufo 1) tb* nlmpla but the blood In not much over lb* nexaBed opper *uaII la111* tost* *ned ia nbovrlag only mlalaval limit* of tbo Dermal of Jtfl. Many bam aald that artdeam af bod abaoeptloo by atlppled call aad If w* bam a reading of bod la Uw aria* of porphyria, though tb* quaatilatim tout* nboood over X tbol In a lent caenpallUe with a roe*In- deftnlte though aolenl* Indkatioa* of faltly lent Utn of bod Intoilrotfem How ever, each a heavy bod abeorptlon. Thin I* tb* can* wborg arino lewd bvt rertaloly of llnetf b not diaf- tb# air coaceatratlon baa fmqaoatiy baaa arar noetic tf bod poiaaolng. Heme of time arino tb* nofn limit* of X mg por II cubic amt*** af * mlon* run quit* high; met a* high an t? Aha, air. Tb* operator b a rath*r coonctmtloun u**r the blood bade la many Inntaaco* rua high, bat uf tb* pewltlra preenum runplmtor nupplbd him. the glee nbow ao tymptemw. Hot bag ago KU bad aapoaur* gbowa by air ; How I would lib* to point ml ran* 111* baton** aumpbo wan an high a* SI mg par It rubl* ran* right la ran* right, wo bad eery tilth ret- mntnru, about nemw limn* tb* meant leading af drew* ty qualitative leetn of heavy bad abeovp- XX Tble nun bad worked R ret an a band migar tlan. la rau 11, then mu lb* uf* limit of bad and than aa a panting mncblnn oporatnr fog R la th* urine. It. and la the Wood X*. but ew yean. Al no llm* bnn he ever had am* minima! qualitative teeta he bad a two pint bad lla*. tl nympteww nuggeetlm of a panelbla bad Inloxt- etlp|J*d rril*. with 7t' KnviMigh44a. and a four rellon, but we barn watched klm rtoanly aad plun p-q-tirlN Ifvr* the qualltallv* fnoU nroru rceoenmended Improvement* la bin angtaanriaf over lb* qunntltnllm toot*. i perinrtiea. HEALTH IN THE STORAGE BATTERY ISDUmtY 11 Tb* Quantitative taata arrod la m caa* (number U, Flyura S) by ahowiny normal llmita of Wad la urine and blood, whIW th* qualitative teat* warned of danyrreua load abaorptloo abow* by Wad Una, atipplad c*D and coproporphyria la tb* urin# a* wall a* a modern* aaceodary anemia. TbU Individual hat never ba*a UL tbootb b* baa worked la tbla ateraya battery plant M yaart. Mock Improved aoyioawrtny pretactiea baa bam (Iran blot and nor* ia planned. Arid* from tbaa* two caa**. tb* rrmalnlaf IS ahourrd tbat tb* individual* bad potewtiafly daayaroai* Imb of lead abaorptlon an rneaaorud by both qoalitatir* and quastitalir* atodia* of lead la aria* and blood. Tb* advaatayu* and dUadraalaye* of tb* tw* lypaa of teat* may b* aaalyatd aa follow*: L Tb* advaat*y*a of lb* clinical aad qaaHta- lb* Intt. A- Practicability, with tb* nacaaaily of drawiay only frw drop* of blood aad with only n racy entail nmooat of tlm* demanded of tb* wt any from tbair work. B. Speed of driMmination la noteworthy, taklns only l( miatrta* ia caao of each atipplad etd cooaL C TWn ia no likelihood of bad coalamina- D. TbU mafbod maaawrr* both bad theory Uoa and iatockatkaa la lodjrtdaaJ caaaa. 11. Tb* chief dlmdenatay* of tb* ciialcal nod qwalltattv* taota ia that UmorrllcnBy tby nr* not "apariftc" for Wad. A. Tb* bod liaa ia IndWtlnyubhabW from a blamatb Ha* which fonwedy waa quite commoa Wa Uwmrth *aa need for tb* trmtmmt *f aypbllia. At tb* poaiat Um* penlcifitw therapy baa rapiacod tb* naa of btamotb. Tb* tbaoraticsl peeatbilitU* of a Wad tin* batay roafaaad witb marcary, thallium or *lhwr art **ry aatlkniy bacaaa* of tb* cbaractar aad rarity of aocb Indian particularly la a ban Wad nrbar. B. Stippled nil* art not apaciftc bacaaa* tbay may b* fond with any ****** anemia witb a Wan hamoylobi* da* to carcinoma. Hody. kia'i diaaaan or leukemia. la lead InleiieatWw. bow***r, atipplad rail* ar* vaaally pleollfal witb a normal or **ry all(hi reduction ia ImwfUIn Aa Cabot pointed ml la III I. lb* findIn* of many *tlppWd rail* witb a r*iail*ty atlfhl drop ia bammfUbta ia cbaraclariallc of Wad latoclcatloa It ia not our belief that any on* afed room of atipplad c*8* U dlafnoetic. Witb thr*a or four alltried cella we Mr* at** aa wtthla normal limit* Wbaa atudylaf a lead wother, |f bit at I tried rail count riaaa *ult* rapidly within a law day* from a baeelln* of all t 10 p t* It or >0 or Otar, on* ran predict that ther* baa ban* a breakdown of enylnawriny protect!** each aa with a blocked axbaual pip* or crachnd lead pot. If tb* atipplad mU car** continue* to ria* akarpty whe* cbached retry two or fir* day*, tb* man can tin mo**d before Wad iatonicalioa occur*. C. Coproporphyria* In tb* srin* may b* markedly poaltft* do* to Khar Intoxicant* auch aa alcohol and barbiturate*. bo! la tb* known Wad worker ft* Andie* la a frsAk four pioa carta* color U moat likely to ledkata roproporphyrtnuria from Wad iWwpia*. Ilf. Tb* ad*nnt**w of tb* qaaatftativ* teat* are: A. Tbay can b* daw* aatirrly by aowaadicwl and aoterbnkrai yrcaonani B. They caa fir* a reUtivriy rapid aernowIny report ca tb* Irtal of Wad abaerptJo* la tar** nnatar of worker* -- 100 or acre. C. Tbaaa teat* ar* iroty apartAc eaiy for Inwd. IV. DIaadraatafm a# rolyfnf natirtly tb* qaantitativ* taata am: A. There ia U- poaalkfbty *f condamlnatkm la rofWniaa of aria* and blood maaptra, a* wall a* the ehjartk* af tb* maw thiwwitvn ta. efccalainy adequate atrmUkt oriaaa ar a lary* 10 n blood aaanpd* from tb* twia Inataad of a frw drop* from tb* nor. Know lb* advocate* af the qunatltativ* ntady of blood aad tb* ria* warn of tb* laatw *f land cowtnnninnthen of aocb aaanplaa ' R. Tbat* U paucity of clinical labarmteriaa **oipp*d to riv* accomt* report* from Qoanrtltativ* atodlaa af *ry mlaot* **aatllW* of bod found ia blood or aria*. C Tbaa* teal* awaaor* Wad abaarptlm owty and do net make a di**no*U of Wad Intoxica tion. They do not abow tb* effect of Wad on firm lodirtduaL Drtamlaatiow of atipplad c*fb la caao* f bad abaorptlow aad Wad tatasicatlaw b (til af yrrat alfalftranro. fbaldaw our aura **poriawc*. tbla U bora* out by puUWbad pnp*r* of other man wftb axparUnw* la tbla fieM.**-*4 fa obata**r manner Wad abrvrptWw it dtafaoaad aad apart from th* onoaDy trueWat thrr* typaa af Wad latnilratw* Hated below, tb* quwticw art*** aa to whether Wad abaorptlow par a* ban dnwa any IrravaralbW damar* I* the eryanbm. Ald* from lead colic, with ar without anamU, bleb Mean ia SO*. *f th* ***** aa th* commonad type af Wad latoaicatWa from which lb* paliawt aaaally rarorara without twaldual, that* ar* th* rare t% or d' of ra** wftb Wad palaian, TVnirh three may nrr**ln**fty abow raaldual, awrh tompUcatlona ar* ran if property Imated It BELKNAP LIAS AMOtmON -- II mm -- CVJ..I MUa Cm 1 1 1 1 a t* it n ii M M O.. *... Tm Wtoi A. to* t. ton t. tom. A. tWy to*. f. to*** Ct* h*n, C WUto t. om t. Om C P. M- Cftot C. AM A. ttod C am A. Batoar II a a n 4 1 11 n a a a a i a imco* ` t 0 t -0 m*Cta 0 0 0 " " . *w ^iaii OaUra Ht/00 M0/I0 lO'W m/n 00/00 mt/n <11/70 171/70 00/70 M0/00 00/70 10/70 \nm 00/70 iK/n 00/00 00/00 </* tO/00 (tin IM/M 190/H 00/00 10/00 170/100 mm mm 10/00 *mm mm W|i-- 0 Mlm 0 UnnwiyW N**tU* In mmMm N|d*< WifdOn Ni i.0.1 fUf*- Wdf H*f4<b Ml to Na Baa Ml Wtoto Km aa Mm K to* Ml V**MMW* Ml Mm t to* Mt to to*. KM Wtoto to KM Wtoto Bn. 1At Wtoto Km. KM Wtoto to JM Wtoto KM VtMtoU* KM Wtoto to rat ttototoW* KM OJt. <IW mpMf*. mr u opatted b--ll*y pM of Duw month* to tbn* yann. la IK* W7 nn Iwtuni of l*ad mnytoalopathy ocrwrriaff to adoK ndm to mod*ra ladaatry. If IK* ||IM motor* IK*r* ar* uuSjr no miih Ih ." Tb* a*arcK for kldda rmidaab of Wad tbmplion *Kold (a forward. For rxarapw. IKr* Max b* a tranaWnt, aoadbabtlay M-cundary aatmla a aKawa K*r* la two cam of IK* It c o m* promM to IKI* (Cadx (goaUn tbn* aad Bra, Flyan * >. TK*r ,r brine (ina Iron aad wtQ b* BKrrtd tmaporarily from f*rth*r he*ry load xpoeon. W ar* aUo coaataatly mrrhlny for powibt* obJ*ctlr orldroc* of any prcmaornt laJ ary from chnnk Wad ibnrplk*. Flyara 4 *Wn IK* year* work*d and IK* tyattoaa aad blood pnooan for ce*npari*oa with Ih* lint* wh*a tbr am war* hind many y*an yo, aad aow wtlhia tb* U*t month, la only on* ran* wa* |h*r* a rl* la blood pro***?* aad that not to* mark. Thk* rorfrUl** with tb* report that w mad* prrvloaaly on Uond pnotun la work*** la th load ladaatry rtodlrd ovor a B**-y*ar lira*, aad at** with th* roport aad commonta by Dr. Mayr* and Dr. llamUtnn a* to lb* fart that lh*ra (W*a at Mwra la b* aay drAnlt* comialloa b*tw**n limy, ton tinned Wad alworplioa aad aa iarnoM la blood pnoturo. Th* routla* aria** *t*4l*d for mlcroaropl* ftadiayn aad albwala w*f aB aoyalfr*, aad to addition, lha total o*ntai protelaa won all with- to aarmal rum -At. la or own aportonea aad kaewWdy* f tha iiUantura, w* an Wd to ball*** that men Wad ahaarptka wltbont th* aymptcaa of bad palay ar (onphalopathy caaaca d o pimnaml phyaicnl bam to th* adult bumaa. Farther, apart from tboao ran cam of colic with abort parted* of ante dWabllity, then I* so lacno** la plant ab- a*at**ia or km of work ability to oar aperi ent*. Tb*r* I* a!** a* w*lyht kaa, no ciaultonit blend proMur* abnormality and d o damayo to the kidavy aa nmaand by roatio* aria* aaalytla, wbiW on* m ao oridmeo of lino daatayo ttthor to the form of Javndlc* or la th* Mtlmatlon af total protrio. (flynn 4) W* wooId wriemna roport* of cam of other workn la th* hold wh*r* th* qoallUtlr* toot* m*atloa*d ib>n ar* fotlowod oot ro*tlc*ly aad la detail by a phy*wiaa |ny*th*r with tha more roaplw tuantIUU** laata of load ahaorption. Ctadoilaa I. Toyrth** with cllakal *AoUa*lloa aad ovalaatlon by a phytlrlaa, the qualltaUre toria of rtlppWd raft, h*moylobla aad urio* porphyria ha** protod ff*rtlt* la Mtimallny ImW of Wad alnarptloa. ThU It Into ! th* majority of W*doipoMd work*** etmrvod I* thla ttorayc battery c e :> iU*AW}n.V s.. . . ., ^ -4:L-:r^^atoiawiM&bai&2*t%tfiftw^^''J*^*^^ ........-,,- . -Ajgnt -snUba-ao-* Wi*bete-,>-dia>b. t r HEALTH IN THE STORAGE MTTERT IMX'ITRT 11 plant la U* l**t M >n, aad Im 14 Ml af tb* IS eaaou dlarsaaad la thU paper. 1. Thu* qualltalln taata ban MW falbd la wars of heavy M tbaorpUea la Una for morinf or cthamla* protarUsf Um b mo . taropt la Um ran liutanr* where micaer-mot or orhr bar* baaa unablo to ceoprrat* Innadiatai/ la Um roccrnoMndatlona of lb* tnadlcal dapartJMSt. 1 QttaaUlallr* raaatlaalioa of lb* aria* for M I* a awful aeppboMCtary aid la anltaUai bod at--orptlos la tboa* Inatanrn oh*n tary* loduatry l* fiaaariallx abb to aapport (bla oust pfkatad and aornr--hat dlArolt laaL t Blood trad la*la, tbowfh rsqolriaf (not car* both la avoidance of welanlaalfan aad la cecopIkaUd rb*mlca] annlpaUlloa. art of pal ralo* for nadinkfil aad rwerth pnblrta*. Tbry bar* not a*tsad practical for tho roaUaa tod/ of lb* iediTtdoal aritk bad abaorplloa la lb* inner bad atone* battery pilot. A QuaUtalfr* and quaatilAlin blood or artao taala for bad an not of Uh u b h Imo liiiaotk of bad lalmkatSoa. Tbry an mritr aieaa of bad abaorptloa to b* jedfad by lb* phyakia* la lb* llpht of lb* *hol* dlakal pirtaro. (. mqorat clinical oiamlaaltoaa of wwbr aad nwiplace bp lb* aamo awdkal aba*rear, loorlbrr rrllk qaatltatlr* otedbe of blood for hauracbbla aad aUppbd nib rtasiafd aerially rrrrj frw day*. a* art a* awaaloaal aria* por phyria bad, an of moat practical. b*lp la physician oaprrband la th* c&aitaTdMtrel of hceltfc la lb* atorafr battery ladaMry. t a ,,ii c. an um* T. r*Miu. a a fm >w mt *4 tow Mf>M hiwnit V4 TO. IM, wmmrnm 4 ttoi I tow* L I rf Inrfaali Ito hWato < 4W4 4>t.bW ^atofiW H M friainUi. IM4 I Itowt tax *4 Amim P. llwilwi mw * *4 P-->L fbojw I* Lm4 PWi i im Mud ( ( .fttoiMwfw, tl Ml. IHL 44 A U <tot a*4 ft ft U**1 * *I * V 1 ft t ft Nw m4 4. ft Fail * * 11 #4 >nd rv l 4. tm V' 4m>iw * W MaaMrd > 1 ft. 4. IwHa* tad 4. I I'Haary hwWM f*t ka U>4 4w *h *I OniMlmd C. f. Ilatd-M, 4 OmtaHoto ftto. mm- ** # (^npununMm fe |to *atob 4***.! W FMadt< Mbar *4 (bnMM< MaMW--. t-ffft MM f t. Nwfttot hidnii* to Cmmw mMmo I N*w bW ><-- M I4 MM * L to*** 4*t**to *4 NupVtM f<4 | Ndniba 4 |m< AUMm Madnd * #. ( M IM IMS. || Mih A I* tofWj, M, I IM. IMl It >* A IMM f AM Mw I. to****, V f t --*> u n * , i h i * .* i mb n* ft !* *a* *RIH t ?**. ------------` load IpprabW W Inf Nw*.*| Aiwrt.t Mto toM law * 111 I. hfl H, IMA 14 W*LMA F. HbMbA. Cllto | KUbprapbr (oard'f) fton to tto AVii>!! M Ito Piliiilto 4*NpMtoM Mrfwaa. . IM. iMf li A 4 A IlifaafM* to L I tom O* to Alto* ato idi**n 4 A*m* i to Lto tobdiiM QmMl 4wtoM 4 A*ad,nan. 1* it. IMA H *UAW f lamtA. TM Mto UM iMUMIW m4 FiWto# to totoM Cafwi ft 4 U4. 4-AJT-Aw ' CNatXMajr poorWTca: Aa yon sdU ban aotrd frees Um precraat, a dXacru*lc*i bad*r baa bet appelated to bad lb* flnuka Idbrlti orb of Um pp*r Mr. Wiliiaaa Pallba uriU bad Um dlacraaaioa of Dr. Brikoap'* papar. OWCUSSIOM ca. muua a. rum: I iblak *a* *f tb* b% pr*Un * ban ban b *,* ! bad trbolntl--, aad a* far a* 1 raa or* frna a m**ana*a canpnfeua* tba pilot *f rlr*. Ukpi an prirail) rbaaetae aad tb* aortal diaab ka* bnc*t an aad non tkta( aadnr tb* urton** cenpaaoatba boo. 1 tbiafc v vtU ban laan aad --in *f ttm IMb fflaieu** *lkS ban amni aad ban bam pa*a*d f b*fan, obtrb vtll Saw h* citad bad la* iibaltia. w aao. tf asyt--dy iimb ttm. than --p be tnabli; tb* auaa b (Mac * fmlup bod taCaaVo- IM aa b* b rM*c to ban a |-d ba> ibb If ** ban tb* nldian of erta* aad bbad boda urfclab amnad ebat *a (*o*id*a biuw Writ*. Ibao Um ladaatrial Cnabbt b (Mac to aaaalduc tbs* Um .. m ft*# ' T ft, ftftur* I <mwitrUi wy (Wrfp toto Uti wftkft 1 Mvt UM Aft ftWof. WU fm nto Im IW U4 Iw 4 Wnk, wttft f*v n/lln On f im a Q Ia iiw m C 44 toft P*r IM ftto f W4, Uf i Iv a i* (to*lUrv4 Ia W faifttim WfM, i4 IWm tov i ImM kl W h a w i< frw ' tytoirt 1* W4 ncvyl yawflJ; fttoto 14* I 4n 1 iMrntoM AttoWf 14. B Ia i Im4 Haft lto IkAc tor |Ma F^F^/rU. tot M toftoMy tot Intotoft a*f (ml M wyiMW aa ftr aa Mm4 rto Wa4 Imft m itfiniii OtUr tftftft tft#4 mm, Uto w Ia m, U H>a 4a . tW fnyfcj'rtoi ftM ymftly tiw Ww ltoi(liHii tofkftto UM ttito toeft Wto tom nynH m Arv fcitoft |a M Ia to* mU Ini It I mM AAtoUftUAl# ft (M frw Uk l(tr to lto ftAAAUutto* ftttoa. ML PAVL ftftfttftfl*Ti It VwU W 4 ftfftVA toMjkf tf w to*4t aay 4i(mI tf U4 ytlwftlAft m lto totto tf tto immM tf to#4 to lto ftrto# a t toti If toy to wit nr tofiwtti m lto Uto tf wtol w* Utol tMA|Ma a i,u m totria Af MttfHil latfifAl torU I(M m;, nM M to nr i*(i>wU in a a I totto. I AftiAA *tU l>r. Htfluy utf (to Itfartria) tqr* ftowltto wto My Itol tto tfUtf (tUlf tf Wa4 Ml lto itoMf Ur*. tf M to lto Mtf. tf tnf to tto IlftA# A** All CWUtoA, tot lto 4tiftA*wM W tm4 to*AA%* toft UnM to Uttf Aft iMUlly tot to to< 4*4 M M rtotAkftl toflftfft x T *V%V . ,** . ^ -<* "i,' y'*  -Agtka . -wj *,,rJfe-- uSu^um--*; s&&. u DISCUSSION KiUrtAy tt b aca-- w m to wy|M ttot Um a y--vU-- af (to m-- af feayvr, w4 f m--t * Mn 1--4 to-- ta Um bbto k4 Um wn**, Um y--aUr r*U ci 4b*blltty y-- wtU bn, but tbt ImIH, -- I to-- Ukraayk Um y--ra, (bat aba v* to-- acklv--4 --rk a yualvty af Ia4--trial kyviv-- \ d--1 Mb U fbf--vU I* Um b4>vbu*j r*n to (to 1--4 Irak* *a e--ltov -- tv Mark altbva( ML f*iuta: &*ic aa ItouMrUl 1 AM 4t*|tf, wv to-- tomv a f--4 )ek U(fl -- to-- Ml bU--U4 to 4--fiM*l*f b*4 tot-- kadv*. Wbt to-- Ibt, mv to-- --4 to-- *Mt|k l I m Lryi*f u 4* h a IiUmIm lb csy--urv. ato I I4L 4. tt. tviUJKk'. I ayr-- with ibv 4b--*1 -- to-- Avyrtoto aa lb m*lu*l awttorUJ-- to --4 bitof, Tto fvartt-- af Um ykyvbiaa la U4--Iry rti ItolU akbk bti --rib m( ^rbl/ fl U U yrrr--t Ctor--* k -- la4>--U-- ttol ra to-- tottUlb torthc Mm#* falb4. f--*--U-- Iv a far --n 4 toll Ul*f tbaa VWa m b*t b^l k*4 ir--U bl tW 4 to artav t*4 j P$ to Um4. mv bn b4 aa imKU 4(ao--fa M4 to y--Iba mv arv virtually trytotf W 41*--r Mtoitor a rb Iv Wi*r r--mltl*4. vat tblmtvf. to r--ily b* U4 aa 1--4 tototoc*ttM to 4llf * to a. l u m: I 4* M ton! to MUr toto to* toto ieamlWv4; aa4 afl tto raitoara mv raa ffvt, yaalilaU-- *r yaaaUiait--* Mbirk. vba a44v4 to f*ttor, to-- Itol a rrimv k I4>| cvwaHbf, la 4tirwt--. vr to tiff-- a 4)Imm af vytaba vHk vrtot ra Mai wfarow to lb 4t4tf*v*b af to4 > ) <*in#. I Ulto la rto af vbt Dr. K--ibf aaS4 toil tto yvr M may bv abi -- *4 f*r alt, U*t lb 4i*nv* ybyriaa, tto-- la avxkar --ry lii--(If ilnrra f W*4 yiiMlaf to m*4v m}/ wto-- wtaa) lUa--a Um to aaraVar M4 af p m4*--I art--aa. ft--tly 3 ttoU. u4 tba aaly by cUai--1 --m. If tb Ml* tirarl af Cat Tarfc, la rtviylay (to (araryarvtl-- rt4a*l to KI to **f *; Ibl cu b lMtonto4 to vf aari-- --ito lata yrtoataa. fravf (bat tto torar- lb faist--t --tovara ar lb* gmtdrt. m* mar tb yvrvll-- af aato Mill late raClrvbrytaa b |mdj ktafrra4 by a*ajr ramyio li vf wbrl (to amai ay Ihv b 1--4, itol a aki --br --trails vildi --r- Vf Pr. tow U4 a fair fi** y--ykjda. Wfili U tto to--4 la Um tlaa4 af to*4, wbirk ra I 4--*t tow y--cbvty vtol (tot to--to. kirat-- tovk ay-- -- a aa-- af kittortlia b>(--a a aartova Ito alfaHbaarv to rrlalto to lb Mlw i *4 (bv toa4 k**ar4 a*4 mm Umt mv --a lc--. la a to--I y--rbba af Um toto Ibl *u (trtto vK. Mvr--r, al vtob 1--4 la ft--ck*v mirtaub y--%lv4 to Kbto toto to Mviffirtir, *Hh Mfirt to Ito --tail-- --ry--ti-- vf amtov art4* toto n(l<alarjbv. aa4 to 1--4 -- lb* --v vf tb ato--rmtlKy. aa arv *0 Ibv toby mraM a--ywaaUUU-- tafli^*. Nv--r (toto--. (to ayy--arv f ttoirail a--atMi-- f itorrfvrv, tto aartatoU--a vf toMfUka m*. paixica: I v*i wry kayyy to mv ttovv raaalta, rayartiBy va yvrykjrria* I to-- to-- aato4 Ml j I yvrykyrt-- to (to arfcav, If (toy tu to aUrtbv--4 la (mm ab--c to( to 4*. to a mmB ytoat vbt? 94 1--4 aa4 1--4 al--rytt--. ar*\ I toto--, (bv Int toe* m M yrvyto arv rmyv--4 to 1--4. A nraylNr lali-- vf (to n Mh m af 1--4 tot--kattoa. Wtottov to la fUm4 to -- 4-akOac iOaa-- U aaaUivr --ito. *M av 4a, f Uuak. to-- U rwfftto Ibl (tor* arv -- b 4a a-- 4r*H-- paby -- --ytobyatlgr ar --Ur. tot 4a 4ivtUp tof a-- ay to 4v artat aa4 Uaa4 Iaa4 la aat af tto ,v avivd--. Yri --Mac mmI to 4--a. ta aacfc 4 "i*vv kuAtkov | rmvMMvf artov yarytyHa aaalyla. I tbtofc Dr. BvikaayV rati -- tto-- Uav-- 4r--v--Aral-- (to ra) af yraykjito aaalyvfa. aa4 to--atvi ,,*k by-- af 1--4 latoaI--tba. ayyar--Uy to la torkv4 ay ky aaw af tto yvayla Tto-- a-- maay --tor (btaya (tot --a14 to aaU. to* to4ay. tot I tkiak to abac14 to --14 tbt tbk atovrraat Miif to4kal-- yaHv rtortjr ttol (to U4--irtol ml acuaty: t --44 akayly vay to daatoc tola fknmka. ttol t to-- m*4v m rtoiaw to to4i--to toffb-- to (to 1--4 atorayv tottery maavfariartoy to4--(ry, tf tkb m a rvyr--t*U-- m--trail-- (tot --ra W a yvrfv-- aliaatba aa fit, bat I tbtek y-- viQ a-- I to-- yatb4 a* >--tkra. t to-- ftr-- vf K, b art yrt f--4 --fk. Wtot v a-- labtoy y-- (to farta -- Mbat kiyk Iv--b af 1--4 ato--yi ato-- vb-- a* ayyljr vu4ar4 af aaatytkaS y-- rib-- la (to bbto **4 art-- ktolb 4Ugmmto vf ttoa mv to--, a*4 H la vbrbaa Itol mv Aaall aba 1--4 yatvalaf. bat (to --fHba af (bv a*tot al 4**|*t, aa4 Umt * arv a4--(a nyrrlamUl aa4 ftvMvr--, la (kb ylaat, aa la tto aajarfty af aHJb vtov Iv i mQ toltory ytob, Mb-- (toy to-- vtovr--ti--aJ 4vta (kai 4--IrtW fatoa rtortf a* ar-- ta --IbUa artov ar %laa4 1--4 4rtralaa (to rvlatl--akly, Um rvrrtUlto, tot*--a Ika aaatyt* kat IbiAft Of I-- -- 4*tenalaa Um b--f af 1--4 tbaa, I to-- ft--a yva martklac W a yarfakk fvr 1--4 aUvryiba. ) Mkra (kb will toto la toaf aarrvtl-- Wy Iba aaaljrvfe af a --Art--1 mato af r--fK ar If y-- raa -- ra (to f--tt) I--I lay yvayla rttokafiy rafl wklb mv arv rv4arlac Ito 1--4 rayavara. af ito t--4 atoaryU-- la (to to4y by i--a-- vf Av tb. ft--atk<4f --14, (to 4tof*--b vf 1--4 yvl-- *--)/*-- W Ika klav4), *4 (to 4ryr-- af 4aaf*v by Aaaky k a n m4--I |M4m. aa4 ta aar yart f aaawbtto *ltk (to mvvyaii--al rsyo lk *. a* --f --y ttol a* to4tob--I ta --4 to vf (to --aatry (to Ia4--triat C--alvt-- b--r4 ylarv f--a( Mvifkl -- tto 4--bl-- af Ito ykjrvlriaa 4**ff If Um a--lytkal ul-- arv toto a a --vial* a* |v vtobt a yalbai k r--Uy --#vriac frvai )iMi * toay ala --y (tot Ito 4aayar |*rr-- b*4 bt--katba, av vbtbf to baa aitor aavmbuat .1 Ito 4i*f*r af (to --raff--rv af to(vf toad-- i i 4 Ulav-- (to tort-- af I( --rity Mill torr-- t tb--a Ttoy a--ally yay --y--Iba aa yvt aaly far valv-- ra*f* uf--ar4 aba-- tvrtala rrtlkaJ (*--la. Tkto k, (br*fwtf, bat * %<*--u-- vf 4tof>--to U la 4l--Vll*f 1--4 laUakalba. It b aHa akviaaa lb toto vf rUb vkwk atlfkl Iml^ U --Ull itvM i * * V- 'v-r>'v - * *' * ;\ * i / 'r,, J ii HEALTH COSTHOl. IS THE CERAMIC INDUSTRY U f( Ilk# cMiHiry iM W 1*4 t# m*W# ft 4ftfl f rttnk*) l#*4 t*toW*M*ft or |oltrcil)r b| imh UUUt i loWrolory t*U ft)--to. I MWi Un I ml Mi ftrt nt-U# la p--at --t 4tnftf ifU. M | U CMtUAw# 1* ft-- oar pmti*4k igwaltloU-- or ----p--iftr Mi, ao4 *1 ll mm Um alt--aft to ra4ara ll-- W 1#*4 iiyonri. CMAUWAM Kmyrni; Aa la *ut#4 at iW r4 of tho prugrrnm, If It U foiwf U IftYt furtKor diaru--k-- of u; of ttw Mibjada |K*I M-- up ml UU roftfrrMM, is Informal rt--r4 UlW c m U bald FritUr ifUrMM. afirr lunch. That Oft# don# a( IK# U*t of Ifcaoo cunfrfwM, and H mUd rarioo# ptoplt U n thiar* off tkafr dMi that (Karo vft--1 Um# fr*r during tho r--frnorr lt*4f. Wa now p*n from Ov# atonrr bottary Indttafrjr to Ihr crtmmk Matlrr, and Mr. Roaoaff W. Frank. vW i# lb# lUMjr Dlrartor of tW f*ir Corpomtlon *IU bmdqturtora In CW land, la rotn* lo (off M aboot "Htahl Control In tbr Commlr Indmtry." ..~xi HEALTH CONTROL IN THE CERAMIC iNOUSTtt ty ftutsm W. HANK ri nKvMtnlb nlnl, our eoport U Mfvi U irmwlnli aa i>n.ck to a M cowlrU imUna ttut bu W. ucnaifil loi may wlain nrrnlii for ladwlfiil knltli mrtm farad with th* urn. problm U IW fatart. W* ausafartaro wml kaodnd |Ua focmolaa for aa* aa protartim and dawUn rwotiogu far Brial lad day. Wa an Uw world*! lartaat aupplHr of thoaa prodarta. Wat alua comparrd ta tba total glaaa ui taramk ladaatria^ aw ropmrnt only await, rfwclaliird ptftica. Oar eptmtkau drwwg.tral* a Wad oxpoaar problem laaa aliwtnM tWaa Uat of aOwa lodaatriaa mIm Iwd, Warattaa load ta *lw ct*apl**ea pmmlr a diffrtoat drfrtf of afubility than la riba forma Wt alao d*moa*trat* tba twpoctia** of rwogniting that ariabilltf ta Inrrwaad aa tba partki* all* drtroarw aad ynawb Bon aarfar* araa for chraalral arlloa. Oar frittrd gtama. pomtala warn*! for Brill aad gtu* for day Min, r*ag* from th* limpl* trad Uratn to had-aodJuat-alufniaom'potoaalumratriam-boro*iUratm. Tba Iwd naM rartro from S o* S', to TO'*. Oar jrtaaaw bar* anlaa* rharartrrirtln, moaf which ta to rrUt altark from rrrtala typm of Mycmn Tk* lari Iwn ta aa arid-miiting fUn Oar glaum maturr or In onto mrtal or day at liatafilani niflif from Mo* T to ZoOO* f. Tb* matal coating* r*qulr* a nlillntr abort oapoaar* to matvring tamprratur**, aotwrtlsw* a Bialtof of a f*ar Mnwb. Tb* (law rooting* for day bodlw moat bo dmlgnrd to walaro *llh aotaral hoar. poaura at higher l<B|*ntna At prrwnl, only a frar of oar prodart Ion Itanw rontaia bod. On plant u m* up to M.000 poaada of litharr* p*r wo*k M>|*nd with tb* w*kty production of I7O.S00 poandi of (laa*. Tb* unrig* ta Um than 10% of tb* number of pro durtkm Itrmi realalalag bod. On* port of oar Industry dfnrtlmfy atratra a .IngwUr lark of bod phulda. Tko potlory todadry b tkiagiil front raw ftaaw Is frittad ftaiaa ahirk prvrtda bad, *bn BOMB* Ual. la a Um aotahb form. Tk* Croat Hdtaia TotUry Art.'* wkkk la Bow aaon than In yrnra old. wada: "Vn trad* (aad aow otbrr bade Britrltk) propody sad yoa *boatd nprdmr* bo troaht*. Ta katp yaa, oar ag*ary baa mark p*dBto aad tkia ikiolt b* aprdfrd to year prorooB." My poracmai istrodartiaa to tko bad probltai occurrwd with By oaajgBarat aa &af<y INrortar of tm Corporstioa obaot t*a yrran agar As any aafrty taglawr will do wkra ompUag a aow aaalcamcal. I *arwy*d tk* grrilli-- can tatnrd withla that arrirnmrwt and I Idwtlbad tb* probbia* that *koald kav* tk* priority of at Imt km aad work. My aorrry waa aot mom ptrtrd tofor* aa rwiptoyr* bogsa akowjag lyag toma of aralr bod latoxlcatkfa. Following tbr tkra pmakat prartlr* la la* duatry with bod npoaort*. wo atr*raid a8 mb ptoyww la oar plaat aad taboratodm with tko atlpfdrd ctO roast trchakjs*. To aaalat oar Sfd* leal llirortor. Dr. W. W. Markhy. a0 aralVaM* lltrraturr waa mlmf. At tkat (ifn*. tko titrratar* noilalaad alraoat a* nfirwn to tb* aalablllty of bad gtam rompoanda. W* did tod data rotating to toprupaopbyda prune* la artao In bod *ipoawr*o. Tb* drlang tod TrnBrrg tool wai Immrdlatrly oddod lo oar battrry of arena Ing t**U. Tb* laltlal rtoaha worn wry mtroarag* tag. A quallfbd nwdkal trrhnlelaa waa rmptoyod to rootlnoo th* work of tmtlng oork | and *mp!oyt rath awolh with tb* porpbyrla chock and tb* xlppbd toil chirk, Th* mult* abowod acroptabb rofroialtoO. Ta* mnwrYatir* mrdkal Jatinml that bad to ko nppltad lodkatod tb* d**ieablllty of non t In ltlnl7 work. Artiw aa this (I) Wa iactndad. and atID do. a porphyria wa- i mo w i1 |nrlM > nnpMalr equipped laatlaa oa lb* pro awiployawail aria* aparlaiaa UU-raiory ud wtlMriud tlw mflcrMst of a which la a part of ovr omp4ete dlakal a*am- UutbmM. laatlaa. i fbveral tanking* n bald iamb-lay plant Thl* aid* Uykt la iatersetlay bacaaaa wa nupervblori, pleat wpltjriw and U> (Ann W atartsd tka prarUco la aa effort to prorida wr nakfa. Thv purpose of these b mUi |< wa* typa of control for oar work. Oar medical dm U U men oltk oar goal* ami the parUneet hae csotlaoed Ike practice became a i axlmik fklH to rwb Umr . Th* mttiip pooltie* porphyria la aay Inm. aa a part ot -uatalned aa admission of oar lerapariaare aad tka pro employment phy leal amaralaatloa. akoold a fwuilK Uui Um entire program nald bt b# checked oot. It b a alga aometklay U arraay. i > mdtirtad la Dm rf, Briefly, oar ebackiay Ml kaa revealed a few cam Tea fan ago. tkb approach to a prpMem of of aacentrofled pro-occopatkaial aapoooto to bad. 1 till* l;i *u diwaitipd by mm M lada* mb * retbrr eiyalAcaat respiratory nadltbw * tris*. lu*( bark, w* bn arrar bad nay raa- aad two diewfaceted rardaoaaaa. u to mM oar action. Today oar pleat aad Tkb type of arraaailay examination now kaa tka laboratory prmaatl bn fall are mo to iMr approrml of oar Stale Dapartmaat at Health. bad report nnrti and. aa a raaalt at tba Mm Wa aaa H la faar plaata aad tka aaw alamlaaa trie*ties aad Initial, frequently M| aa pin eaametlny ladaetry ahowa a preference tor tka i point their bpaaa la evorklay torbipm tkat tarkaboa. la a few ream I kaa* preatded pro- prodoca alight otmtioa* la bad airna. Tkay ciee alaadarda aad Uwykt lay pieet amployaea demonstrate aa bad phobia. We bn kad aa to perform tka teat. Wa offaat tba qaaetlea of coats of bad tatockatioa. lay aaalaatloa ot raoaita by raqubtoy modical Wi caa report aa|y too ot Ikrts alttallao* la aaprofalaa of aS p*alUo if arlmwa, IS ysara hereto tka family dartor at oaa at l oder aenaal rimmeteacse. aa tenphy* wtB mar ampin] in with vsyo# yutrV dlatarhaaroa prodoco a hoyatiao porphyria aa a part of tka lioad H aarmary to Mika a toaUUi* ti-pM. pet empleyaeeat asaaainatbn, From too to Ml of bad poboatay. Um familiar difirsity at bad sob* foil*slay kb atari to work la tka bad ladaatrba' medeal departaMOta. oxpaomra, ha oil dmnnarirmto aa abented par* Oar r<fartIt* control aiaaaaraa ao*r lactodt: phyrto. aaoafiy ot tka pla* aaa or pla* two mo-, (I) Tin(b*|mf tiollifef per week. <1 > Ray*, rirty. Witkla two to all wealth tka drcatlaa br katklay freon dally to Maraokly daptwdlay aa disappear*. Wa prssam* tkb It accowatod far Job awlyaanat. tl) Sa amtkiay aad aaliay hy tka fact that kb phyablayy b adjaatod to Uboat prior nbiiy ot taro aad hands. (41 tka new antnsanil aad b operating ao aa to Bmuklay aad taUay prohibitions la prodartka receive pad dbrkary* bad below tka aaitlaania artaa. (t) Daily laaaa ot a ebaa raapirator. Each ptrmlasibb brat I eU aet dbputo tkat MU aoptoyaa b aaaiyaad two. Only tkraa artaa ara employe* iadortrtaatioa prodocoa a dryrta sf "raapirator area*," yat a aaabr ot awpluyn* adiaatoMst la prnoaal haUb aad kyyboa which volaatertly oaa raapirator* |a other araaa. Wa rosU prsdoro Um earn* noalU. Both potato kata twrouny* tkb bacaaa* aar ytaaaaa cantata till- ualo* la tearklay rsapioyrsa. ran. rkresaa. tlrccmlom. antimony. potassium, Each mosth ara poMiek a yrapklc dtenoaatrm roppav, aMfpma airkla. boron. strontium aad tic* at Um lead volume procwMed by tba pleat. cadaalaaa, to aaiaa a law. (<| Uaal brkara: aaa Wa think tkb b Impartial la oar rsb of piac* for atraat cbtbloy aad etM for work cbfhiay. lay all tka carda oa tka taMa. Early Is ear Oar Ubaratery work Included comparison* at effort* to adoceta the emplnyeaa. H was possible quaatiUtiv* and quailtaUv* porphyria dadlaya to trace rartala lead produrUcn Ham depart- la Um artaa wilk blood lead*. ariaary land*. aad aeat by departmeat llwitlb pleat, by ecnaa atippbd taC rotate. lay teat result*. Today, with tka eaylaaeriay Wo bailee* Um paephyria rback proctdid a cheapen aad baprored s**(deyet aduratloa and boitrf bad aaraaaloy r*aminailcat than CosId b* attitude. It b ao lawyer poeelbb to de tkb. In f obtoinad by etamialay Mood smear*. Wa **U- fact, wo sow dad It dlfVwtt to ebtol* a lerye mated 11% yraalar accaracy. Wa wor* farad enoayk yrowp of empl-iyeew wltk elfalflraat poet- wilk aa trrubmal asyatlv* Mood Motor wktek live porphyria* from acraanlay tret* to obtain war aid mtntal by a aryaUaa porphyria, la Mood aad urinary bad* to malt* tka aeraanry addition, Iba laboratory (nolaiinly demon- troao-ckack* era think ahrsiid ha a {art of a com "I atralad tka aafu* of Iba fodowlny potato; (I) parvatlea altlluda la Mr *' trri program. Tka aparlmaaa wor* more tkaarfully ytaaa by la our plant * taat IOC amployeaa par tnooth. tka employee* ill Tim* and trowbit to abtala la yanermh trace and plua owe positive* ara of and prone* tka aparlanana war* yroatly rodwrod. Ibe yrvabat Intoreet to the employ***, auroaa aad HEALTH f-OSTROL IN THE CERAMIC INDUSTRY the Aafrty Ikpartmeot u thay may MlnU la- Important aa rocogaltlo* of tbr fart that lltbarg* dlridual or (roup trmd*. flu* two'* in n(*m< and many other bod compound* do not rtay air to lb* medical director Mid Immediate aupmiccr. borne for more than a fraction of a aenmd. One- The *upmlK)f nrim working tarhnlguoa. Tb* bundredmmh material la air-borne longer than decior*a check Include* "pwjkjrta tO-tn**h material. Abo. larger pellet, oil) meeo chock*.- Depending on clinical Aadtnga, era- In lb* batch aa It la worked In our procoaalng. ydd/em' klitorWt of NBiitidtjr to bod. blood aad I heartily aubacribt to tb* Health and Safety rlwn bod* or* ordered from too plu* to four |4o*. Om year produced fto fro lkn and four DMalao of tb* trod tndoatrim Amnciatkm. Slnco bamtag of their operation* approximately 1 plum Ibt * icWtid lb group to lactase too plu* polUm to ddili II or SO blood Ml l year* ago. we bay* bad as opportunity to draw brevity on their advice and couaart. It la a ain- irlw; bod* o* tbtVj por poor for coolrvi. Cm*V ceee regret that- there b sol score rtaf and pbyew >ob rioaro oat of bod npontl uni or* ueaaRy n!y Hciuir; la tbo foot ploa nuir* Blooey to praeid* tb* moire# of tb* type they auppiy Isdurtry and tb* puWlc. aad the* auly If tho employee boa too mwn* Lood Compound* peorid* a sort saafal glaa*. :-h ti.e ooUf ckecha prodociag foor ptoo. Our Isduatry b Istaraatad la sew market*- I ta I belie.* tbot lb* pobiiabrd muimum atVrw- roselsced k *m nrw product* and market* wiS obb MMootrotka of 20 aUUtrim por cable regalre srw propertb* la our product. Tkaea b BxUr of air >b*U U mined to prweid* a Kf- aa rrwaua la avoid tba aa* of bad to reach them pnM alboabl* csoceatralioa for och bod goal*. ronpouad. Oar bod rompoaod* roar* from 2% to TO', rbmmtal bod and o bn obtained air oalorn ap to M miUl/ram* at bod per ruble nuMt* nowptrcu: Tbo paper by Mr. aotir nitb lb employee* abowriag arro aim* Frank will now be ditto** cd under tb* lewder. tbo la bod aboorptioa aim*. *klp of Dr. f- H. Ills*, who la CUnkal Frofea- la oor cam, tin probability ad On piaat worh- aor of Prrvewtle* Medkla* at tbo L'nireraity iat an on* bad rompoaod raduaivety bad nm|t of California la Saa Fraacbcw. to oUala aaiaplm U meant a. W anuaHy bar* moral aijanat amrltrra or grtndtag oparatlna* OttCUtSION pou anting a arpormt* bod compound- load |hn an. c. a. Bum: l ahmld like aa rermpkaala* that compbaaa obey tb* lao* of tamparaloro air.a* tb* appear*nee at perpbyrtaa la tba acta* I* art tie*. U, aborted tamporataroa oiO prodOCT bad vap** whet* degree at T*|mrliatba la aim | blad to tbr tbrmkal napoHioa of tbo gbe*. ('rftala glam compbwa cbemkaRy bind tbr cool* pMHrot rao amteetala lata klgbar mobility. Oar tarbakal ataff aoggeuta that bigb aiomlaa baa IU> property. mloly giegamtk at bad lainabatfaw, time bcTeaeed arnutba of porphyria proc area* error, b a macaber at gkiaeeq. mart at whkk iaeefe* the beer ar tb* Weed, hut wkkh acty aim eltend W kartode maatal du.n.cn. dkeatea at the alia and chcenk lafnrtloaa af nnoM typne. There ar*. hew Iir. goalttatie* m.aaim fee dktiagalahlag b.twi.a npupirph/tla III, the dectealire of art kapwtun la tbb pub Otbrr tarbaical prrooond bn affrrrd tb* *g. lem. and ather ctemly related procarmt* at hew A gmtieo that tb* ll|bf lb* Tmborr, tb* graatrr gtnhi*. Reeewtly. Mladew and Thiele IA red. { Oewee- :,i ar higher tb* luckily. Apparently ihl* approach kpeil. a. CceccHpr, l*;3Pd, IHI| d.mwaetraled t* Tarioaa ladart rial toakity prablrma need* that the warntee at didrrewt ariaary porphyria*, a* i mn atudy and rMMldrratiao raiatlag to arret*! trootlmamr compound*. d.maaetrated by paper chromatography, Incroam* with tba inrroared atrirptbw at lead. If aad wbaw mere .pertAc analyma are regained, then tu bo Macb worthwhlb pmgrraa cmId be mad* areaanpilahrd. 1 da not bade** at tbb that that a by U>* bad producer* If Ibey wooId rooaidrr diicomlrt at tb* esnet awehaalam ad tb* fenarlba tb* problem* they ar* trying I* ante* from at them aaalrrtab I* Criernot. alar* deepha raw- a awce prartkai |*>lnt of view. I rofrr ape*I Arally aateralda reoenrrk week there are many fart* rtil to a rorrot alleo.)* la reduce dart by pellet IfIng lilbarr*. A* I andet.land It. mnt of tb* pellet to be riorUelrd. Hewrerr. aoMea M te my that aa a trrmalng procodara. three la a high drgem ad Icing binder* Introduced *admirable pmpertim Ink* the Aal.bed glaa*. la one or too trial roM land,log peUetlred material abort one-balf millimeter In diameter. Ihe grinding ncitm of tb* |l)<l. en owl. between a plant and our ml* log department peudured an onueuaQy An* dart abkb gam o a Km.ler roarentrntioa of dart I Ken w* nocmalty npeeimee wllk untreated cmrotalle* Mere* tba rroetta of alee* I lea la them cwprwpmphyei* oalam aad arlatry and tlmd lewd leerln Thle Wrt U weed with Inrrraring fregamey led*/, lie eaten wga mrngnlmd hy a* tome it year* ago, and w* bae* alar* laatrartnd tor awdkal rt*. deal* at the L'alrecelly of t'altfeeala la lla am a* aa Indea at lead abmcptinn It la aadeeetandiag Ikni a nemhrr ef ladanletm am tb* pfeeednre rather wtddy. litharge. Tb* ala* of tb* pellet may got be at The rolaUeely Urge portklo ala* of Uw glaa* frtt* f' II DtSCt'SSION 4 Um ttoaalral atrariem at land wttk It* lwr>ir>- Uai a* a InnU i4 MlmU ill aahtfat# iftlwl tW (t Um let* tlx tori/. IHapite iIw m luton, M enM to M; rwwwii4*tl* Oval mt Wu i eiitHirv Um UimU Mt be (IvM U ll*rl*| the pr**eal thmwkeM limit nl>M at O.lt tor-- M'. yriartyallr M Um Util that It v mM rtaHw*U Um yrtaal luljab, UM 4*UnUuUM mI4 U fMln4 to Infant* Um mUu w ^mU|a af Um MnlaruUr fomn pt Um fttferant baf Mr. frtol^ etuclt-- kin, kmw, mbitoM IntM to Um Mi4*nu*4iif if kaf Uw4ip am Im haa |M*1*4 Ml teat air tunetiiUMt af |n4 mlmU aaf Unu mUknU)i Um tkmkU IWa aWa raHU< with datmnlaatiaa af baf mrrettoa Mt- toraa u4 Um (hyairal atet-- af a|iy*M. bn fallal to taniUM a*/ nlfiaie af rMbr fiwl aa aateUal--I lateikaUaa. la affttton to Um rup if> Ok ; la Um bU af toahh pnlirtln far Ha m wa|lyan. ani| artt baa the tnaya--iWillty far aafrlj af Ha pnl art aabr unfit-- af arflaary am Aa Mr. rnal haa infirmed. raraaib pnfxlr max raalaia reatifimlli tiaatitM af bat, aaf aa anrealm they hare arm which briar Um* tala caatact with tha yrryarsti-- ar aarclto af faaf. It b my wafer atnftflft* that tha iff--try haa *nl<--tarUy nirrytaf a Maatuf af Um waaftUty af fiaa baf arhkh <ma ha ctpaUf ta ha attracted fra-- nauw eacfersa. la thia r***tf I a entf Uha to fafar to aa--a rnyeci- tawa aa had aa tha Wa-- Caaat with tha I--pact af nan l--prey irly (toaef aaf palabt flitoa fraai Jaffa Aantynto ahaaif that tha (tear real! na- tala aa hi<h aa Mh aatrnrtahfr bad. aaf thb aaa frrtorf to to a yahlir health yraU--i a-- M aaa frit lhal taaUaaaf aaa af flahra with aaataHa Uahi(a laaM malt la lara rtiaa hy caaaaaaera af Ma|t baf anr a f itli I af Utoa U rawalt la lb area. Thb yrsble-- haa toaa cafTKtat atthiat nay aarbaa taaaa tatoabatlaa. I aa ear* that fa* to Um rffartf af tha Health aaf Safety Dtrtoea af tto Laaf lafaatrb* AaewriaU-- each ffIII-- ara acalfif la Aaeartraa tafaatrjr. a*, nut: I aaat to --jr jaat aa* thla far aar Mattf. Leaf re--pi aala (im a* --are aaafal (toaa. Oar tftd--try b lataraetof la a-- --nrheta. aaf I aaa raarlacaf that ara prefart* ar* galea to IP fair* aaa yca--rtl-- whkh raa to ahtalaaf tnm baf- I bn aa naaaa ta aralf Ih* aaa af leaf to raarh thaaa y--la i*l ana: |a tha praUa-- af baf iatoalratlaa ta rhtlfraa aUll aart fall* fr--atly la tha Baataa area aaf tto Carl! We feat aaa H nrj aftaa la Callfnrmto. M. a. a. arena Oar baf y*i--alay b wall/ la chIlf raa aha chaa pal-- aa Um tbaf haa*l( that aupataplatlr ItTO*a. acr* aaf *C"a Merit af thb b yaiatod *Ul baf pl|arau aa UaU* trba. At anryartWaUr haeyttal. a* a-- aaywtor* fraaa taa to It cafes af baf lalaibalba aaaaatlp. Vary fra of thara i-- fraaa aay attor --area. Wa hear aa acraabaal raaa af a rhSf fraaa tto rasatry atora aa nlf-facht --f I--< rawlatalar --t--r-- haa baaa epylrad to tha achar'a atppln ar aa--<thka( af that aart. hart yrarikaIty aB raa-- ar* fra-- the aery <h--y haa*la( af tha yrrtif an--tioaf ta. Hues: lUa aayeaa haf aay tipnbaat with lataabatlaa fra-- aster fra-- baf ytfra. arsto to tsakattoa? W* toliree that each a p retina acranaf atoa tha asur --yyly la tto altar (art af Saa Smarta ss* Sant Daria* that tbaa. the baf tut--t to- crianf (aha a tot la tto water aayply la aa* area, which a* thaachl prate--f a ha--rf af baf brtaat* --tiea. Km aay--a# at-- haf eiyertoace wtih that? a. a. taaaa: Caa-- to afalta Mill naUaaa fra il--a ta Ua--. yariiralarty la yaral an-- atoa water b --a--paf to a haa-- fra-- a ayriay -- aatt la a y*Ce-- ,< baf papa*. Wr a-- taa-- af that Uaf tnm Ua-- to Ufa*, aaf ttoa them am aba at--alaaal --*** a--a to ara hr--lay fnilipiar--a atom tto latiay af water yip-- with baf--alabile hth* Material raanha. f-- a parted, la a M(h baf aaa- leal ta Um aatar. . v ' Th--* ara rare, tot there ara to tha IHa rate-- at haf twa Papeete af atriaal aylfr-- lea af thb Uaf la laryr ara-- af ara ha abac frail!) Mlat*. CMAldtAN tortrtrmr: Oaf flacaael-- haa (CM rather far afbtf fro-- th* manic tadaatry. Oar Anal paper thia --nifty will to hr Dr. Ilrtmalh II. he break, treat in Dimeter af th* lad-trla! Hytrin-- Sea--fat ion la DHularfi Dr. Sckrtnk win apeak aa *llyyk--k leaf Stead* ardc," a my brmd *oh>art. < HYOIENIC HAD STAM>ARD$ Ay H. H. ACHttNX, Ml O. *Tlw elynlAcnner of hyrltnk etaadard* d*p*ada bad. depending oa curb variation* and tha effect* r A u mwk H rMnniitiiatlait aa It dor* or that peak concentration* may have on the worker. erWoce ud Urknokfr. Th* ItnH hyrlrat tUnd* Ilmen, the kypnlc rtaadard may br aeon ac 1 ard, maximum nlluwnl,l* or accepiaU* toncro- curate than thr analytical data obtained to tvahw trulion. p*rml*JU* limit, thraabold Umlt wad atr It- Thl* limitation of air analytrr can br hyrirolc fuldae wo need InUrchanrnUy. Indi mJntmleed by laatituUug engineering ooatroir at vidual Interpretation* of the (f>rn or* certainly mc it m of high centaalaaat dieperxlon. tha* re not liar u m Thl* U partly owln* to a lack of ducing peak ccwcmtndion*. Thr clear rotation- udantudlu of thr tarhakal nrprcu wad Uar ahlp brtwora thr ttaadardr aad aampUng aad purpo** of Uar etandard*. aad portly to Uar fort aaalyal* la obvtooa. that Wool or raoklM]r cooooUUowr nrv In A aafrty factor lr aa aarmtial coaaidrraUea la ferred. Thr lattar to o |rtlnlu otmabilnr Uork antahliahlng a rtaadard. Tha mngnitudr of tbo o there lo > Uodrocy to laor thr ataadarde to aafrty factor may vary greatly depending oa our "prove" that an Injury could or coold oot occur. knowledge of thr biological action of thr rah- Ooly whoa Uar purpo** ood Umitatlooo of thr rlaarr la paotloa If thr potential haxard la ataadarda on thoroughly undrfotoed coo they tar great. If thr margin brtwora minor Injury aad properly wtllited mod thr fnatrot bmrdu ob- poolocu injury t* narrow, if thr Injury produced I* Irrrcmlbia, thra a malar margin of aafrty Standard* of (ood practicr Kara brrra rotate I* nsilnd. Oa thr ether hand. If thr margin ttohrd la moor Arid*. They an taarrd oa available brtacra thr Incipient effect* and Oeetoor injury orirotIBc and takooliifk laformatica and thr 1* larro. If effect* are readily rovorolblr aad Jgfinrat of a imp whh knowledge of thr good dlagaaatir procedure* acallable to drtact particular Nbjott, It to ohrtoo* that torh oro> natty change*. then thr margin of tafrty caa br Wr of thr group wig oot ban Initially thr aaoar omall Thr type of historical actlro 1* alao Im- oonarrltal oalor la mind. and that thr Anal poctaat: for exampia. whether Up* action la oaa etandard amt rvpraaieit a cornprowl**. Thr of promwrlv* ayatenatr effect*. aarcoai* or Irrt- Aran Anally arrrptrd wiB ho a "round aamber" tatkm. It I* noteworthy that tha preamt accepted and not aa Irunct" Afar*. Staadard* aunt ho etaadord of I ppoa for ehloeta* aad hraealno b nn*W for what thrf an, thr marnu of the aaaar aa (ln< la a table published la 1913, a imp tamUm# It* bm Jadymewt. Thr wlwrma valam for aolceata. ouch a* benxol aad Aran accepted U not a Aaad aciratlAc talon carbon Utrackloridr. hoc* been rrowtly reduced. and might joat aa w*0 hat* boro amurwhat It ohowld br rvidmt that a Agura la a table of tmalloe or larger. rtaadard* or Uaut* haa no algalficance per aa, Thr parpo** of hygienic rtaadard* U to nm and dor* not define thr rolaUvo haxard. It haa a* guide* la controlling thr indurtrtal rsvtren- ateaning only whew Interpreted la term# of analyt wot to protrct thr htahh and mafort of ical, tcraWelorlcat aad medical data appUcabia woeirca. However, thr Ana] crltrrtoa of thr effee- ta meb loditidoal compound. If thr Ufa] ItapU- liven*** of thr rtaadard and rotirocunratal row- raliom aad oa* af Umita to aupport otbmrio* trotr dom net rrrt on analytical rntiroamratal untmaUr pealtlen* could b*eliminated, thr value data, hut oa thr worker"* n*po*M* or lack of of otaadaida would bo fTewlly onhaaerd aad the rropour, ahlch lr determined try rornprchrorlr* owtaldlehmmt of acvoptabto atandard* would bo !S: aad thorouirh awdka1 *urv*in*oee. The clnwe much We* dlArak. thr eorrelalkm brtwrrw tSr MiTlnninwtUl awaa- Standard* roUtiar to tho eoewoetrollon of Wnd I anmioti and thr mult* of a*dk*l examination* thr Innn mranlnyfal Ihr hyrtrak ataadarda. ta atr. orlno. blond, water aad palate art dlrnuwed la the fcfhwlac aictlcwo. Then an thrr* lalrrrrtatrd factor* which fotoc* thr otfertin application of kygtenlr Wyflmir tlaadaed for Lead la Air atandarda; (I) Ihr limit* of analytical meaaarm Air aaalytm aro *periftr swaaarommt* of tho awnl*. 111 potential arvertty of lb* hatred and rnvlmammt, aad permit aa evaluation of a (3) reliability of dlagnortk pctatdurra. haenrd before wefher* aro npwd. They have r- Thr wld* variation* la tha |*v*ta of air ton- a detail* advanlar* arovr other mmaoromoata tamlaanla la which a wort** may lr offered whkh depend on anmr Wnloftcal rrapnntr of make It dllftrutt lo el4*ia aa late*rat*d mea*w re thr toilet I* Uw tapoaur* Anedhrr Important of eepreur* with a rrwe<*wt4e aumtvr of eamfdm. u*e rf air anal)*** la Ihr drtermlnatkri of thr Tha rcaluallon of tha haaaid may b* |ad of aourvoo of dlntmiaeUon, that dir*rttf anflaatr* II ft \ h J, v sn- Uf :" ft f - 10 SCJIHKNK Inf mlnJ to tboaa point* vrharr cxmlrxd* m Mated nod at the u j m torn* wnlni u a bui* for aelretlag the type of control mart dcelrabl*. ftubaequml to lhr *el*Ui*hva*tt of centred r ml urt*, oir AAkl;M<a ru hr u*ed lo rhrcfc thr rffactJvmeea of thr anrlneerlr.f fncaeum. Thui air analy*** have a onton*# fed* ia thr prerrotio* of harmful or ebJrcttowaU* rflrcta frot* anviron* menial contaminant*. Thr vaior of aoch analyse* to meaningful. how ever, M1; when they <*n hr Interpreted ta tirmr of (Kfnllal haiard; Win* thr Bred for hygienic rtandard* for thr natMlnll of rootamiaaota lo thr air. flrtefly. hygienic etandarde for air ccocratraUun* ar hoard m Iahorotor7 nrrarch aaing a*lmala, rod field rtodiea correlating thr medlral damrUou of rspuaed prraoae with data oo thr nntnttor of contaminant* to which they arr etpnaed. Limited hrmaa nprrimentation fa> thr laboratory and experience in thr nar of a rtaadard rarer tr aahrtantlatr Ita validity or Indicate a artd for rartaiun. Thr bettrr thr rorrrlntioa between air namtnliia and effect*. thr greater thr reflability of thr rtaad- ui It la laanioMiir afford that thr InntUtiaa of thr rorrdta ef animal rvJerriowntr la trrww of haaaaa nrjratr hrr definite liarIUtiona. Haora a factor of aafety ir aard aad thla ary vary widely. A rtaadard hoard aw aaiiaal data alunr to waaaOg ranaldrrad tootatiro. Standard* hoard M fMd rtodira are, la general. aw>r* roliahla. Hot cxring to many factor*. arrh aa limitatiaoa of air analyara (wide foctaattoar ia concentra tion*. jkywat atala of thr (wwtamlaant aad auntbar 0f aaatyara waoatly obtainrd), Wh of prretoe (iryxxrtk Jtxnfum and thr dignity of eotlmatlng part ixjxeom, lhear valuer alro arr rrlaMithrd with dor cwnaidrratlo* to factor* of aafrty. la rthrr word*. ortaf lha hart tout* avaiUUr, hygienic rtaadarda for air ronexatra tion* ara not highly accurate fixed valor*, Uit rathrr cvpement Indt of magaltode. tiarrd ea thr raralta of aa engineering aad medical rtady radalnl by thr V. 8. ftllic HewHh Serxke la a rtorage tottery plant, H waa toocloded that, *T,arrj4 for prolonged nparn, It appear* that the limit of aafrty under the coodiiiona encountered ia thi* rtady ia aa atavuophrrir roarewlratioa ef lead dttel or fumra of traa than fi.lfi mi&ignm* par id ruble mrtrra of air.** frior la Ihlr, a valor of 0-1 mg ro m. had kera aard by mm. (Hh*n warr of thr opialoa that 0.11 war l*n Inw and that OJ mg ro m xeaa more realtetk Neverthele**. ainre Ihe public*, llxm la ltc.ll of Ihr rtorag* battery report, th hyglrnir etaadard for toad hae been generally accepted a* 0 14 mg ro In Thr farl that thla eland*rd hoe h*m toed *ortwa*fUy for about tfi yrar* indtoataa that It ha* been a reaaoonbl* value. ThU doea aot nrccaaarily Biaha It the tint choice nor demcnetrat* that other ralueo of the name general order of magnitude, *u<b aa O.t or 0-2. tnlrht not have proved ju*t aa aatiafactory. In fact, a rtandard of 02 mg cu m. haa rerrotly been adopted by ACCIH and the llygicclc Gaidar Cscnmltte* of tha American lodoctrial Hygiaoo ` Aaaocialian. The aula compound* of lead tocouatarad la thr rtormga' battery plarrt were: PbO, PbiO*. IVI* and PblSO,!* aad there fora tha figvra 01S. prwvioxuly quoted. mart refer to arpnaora to then# material*. However, thr figwra ia aomrtiotra a*rd to refer to Trod*' ia aa aB-ladartva manner. Thr ASA rtandard la timilrd ta toad and it* inorganic rcmpound*, carbonate, aulfatn, oxide*, nitrate aad chloride. While H b impraetto cal and annrmaary to aatablieh Individoal elandanb fur each lend compound. It ia raallatic lo make dirtinrtio* between aaluhte aad laaolabio compound* ia rotaUiahlag rtaadarda for ayetetni* poUcau. For example, two rtandard* wm eetxbh*hed fog araalam aad eaaadlam - cemponafia, oor fur aalnblr aad aarthrr for iaaclubla coato pound*. Thi* uat principle ahooid apply ta toad reapound* aad ia prenrolly andar ccmeldecatlo* by a roouaiUrr af tha America* Standard* Aarociatioa. Aaothar important factor la regard ta air roacwwlratioa* ia particle aiao. Thr effective doaa of toad ia that portloo which reache* tha Wag* aad 1* abeorbed into tha Mood atren*. Thi* to auppleniented by the toad which ta retained la the upper rrrpiraiory tract removed by the artto* of the cilia, aad awaDowvd. Siaco probably POV of thr r*allowed toad 1* rxcretad aaabaorbed. a large portion of Uw toad which enter* the rrp!rtory tract may art hr ahaorbrd If the panicto *iir la targa, and tha air coocmtratto*. which ia determined ia trraa af Wright may raagrrrat* the rxpoaore cooditkoa. Oe tha other hand, if all thr particto* art prioeat a* finely divided fntae, Um effect may be aoanrxrhat anderewtiaMtrd. - It I* art no moth thr rtaadard which to ftaafiy cvtaUlehed, bwt rather it* proper wea which to mart Important Tha evaluation of Ihr potential haurd of tha environment ahooid br only oar faced of a Well balanced program, aad ahooid bo rorrelated with mgtneoriag and medical runtrrt men*urea. HyjWt $te*d*rdi Irr land to Ueto* la view af thr limitation* of air analyam and lb* fart that tgponor* to load compound* haa meaning only If toad abnorptloa occur*. It w*a n*lurid I* tor* tr thr annlyiia of htoiogiral material* I# provide a mraaurr of toad ahrorp- HVC1KMC LEAD STANDARDS SI a alnjrW ataadard for tba roarantralioa ef quantiUtlr* laformatloo oa tb* rabllonthlp ba- I ta tb twtca urinary lead exerrHoe and arranty of npoaura, and tb* analytl* of urin* apaclBtan* to Hyftoab Standard far Load b Bead probahl7 lh* mot common procod urt for rraluat- Tba roncant ration of bod Is tba blood alao pm lay lead npoouro aad absorption. rider a helpful Index of lead exposure aad ab Normal urinary trod cieretina varl** front aorptloo. It al*c amt* aa an aid la lh* diafnoaa* about 0.01 my to 0AM ms par lllar to tory* of lead polaoaini by protldlnf deflnlt* rrtdaer* aamplro of a lltar or mar*, aad from 0AM ms to of lead absorption c>d la particularly valuable 0.1J ms per liter la apot aamploa of SO ml ar to raara of aonaparifie aymptomalolety. Blood moro. Tb* maaa oaluo U la tlx onto* of O.OS laad drtmnlaatioru bat* tba adraataye that tba me por Utor. Valor* of 0.1S my and 0S0 ms par aampl* caa ba toOrrtad witbout tbr artit* roopar- litre h*v# barn fnmllp wd aa aa oppar aafa atloa of tb* tndlriduat, aad without tba rlab af limit for urinary M excretion. However. con- cooUmlnatloo. Blood bad roarentrallons art laaa r*otrailed* couaidcrabiy la stems of tbtaa Irrrla variable tbaa aria* talua*. aad la rar* laataac** bat* braa found in lb* abaanr* of any alptlftcaot of kidney Impairment rvttal ocmln abaorp- evidence of Wad petoonlny. Coatararly. evidence tioa ttbera aria* aaalyae* would fall ta do ao, of bad potoonioy baa oczoaJoaaOy loan eta*retd la g*t>*ral, bowetar, tb* ram* prioripit* apply Ilk roccmtratlon* laaa tbaa 0.11 me par liter. to blood concentration* aa to aria* rmwaatra* Aa tbrr* may b* aa etartap ta tba dltribullo* tioau: aaarrty, there la ao tptci&c Irtal af blood curra* of uriaary lead leveta la uaaxpoiad aad Wad which caa ba interpreted an ladlcatin* that r- otpoard pmooaat, a ainrto raaoh hoa littto mmafar. Repealed amlyaa aotlaf trvndi. aad tba bod poiaaalai exist*. Blood bad raacmtratlooa of tb* order of 9J01 ms to 0AM ms art cuold*rad Aodiey* la a yroop of npaurd pareon*. rattol witbia tba aormal ran** for prraeoa with aa on mcanlayful tsfannalioo oo tba ouyaitad* Ibdiutrial aipoaur* ta lead. Value* between t.0t of tba expoaar*. Tba kiyhar tba Irtal abota Um am aad 0AM ml Buy be coealdtnd a traaaitlob aormal run tba yrealee tba llkatibood tbat on*. aad caaraatraUoaa abota 0.0A ms ato to- potoonlny viQ ocrur, bat tbrr* la d o *p*riAc dicatlt* ef iia*afr rxpoaar* aad that ccartral ,d Irtal abet* ableb It ran b* aUtrd tbat potooD* lap aalata. la otbar word*. artnary laad >tya asruures dmld b* Improved. rteu thouyh a* alyaa er symptomc or clinical evidence f bad cannot la lhamaafta* b* aaad to dlaraoaa load polwotay ar* pro* cat. Tbera may b* a dluyraa poitoolay, bat tbry ara of tala* whan aaad la aut rtyardley tb* Ayara* yftaa; bowrrar, tb* ron)unrti< with otbrr data and clinical Aad- priocipb of a alidicy ecxle b rrrtoUty valid aad lor* la tba rvahutkui of tbr elyalAraac* of tba aa k*y a* lb* vale** ar* mad to ovaloato ** npaan nod la lb* diayaoato of trod puUuo- pcaar* aad abaorptloa ef bad tbrra b aa aaad to ptac* nadut aiyalAcaec* oa a vpociAc Afar*. Aa mrotloard prtrloo*ly, arina aaaljraoa amir ladlcat* a loar Irtal of abaorptloo atra tboayh Hyyant Standard far land b Orfekbf Water air conraatratloaa may be hlyb *wfas to lu| Tb* saUbflshiaent of a byyiaab ataadard far particle alee or Insolubility. Tba rrttrtr of tbta tb* bad content of driahlny wator prtaeaU a tlw may occur. la oor laataac* la abrek air rrnmawkat different problem a* tb* opportualty analyta* dated value* trail with!* arraptaU* for rsmlrot, moaltortny aad MirTrtnaar* b aa* limit*. aad tba aria* taliw* vara quit* klyfc. It a* readily applicable to tb* ymaral public aa It vat found tbat tba npoaura vaa from a *o*itu I* to Industrial worker*. Biots at boat IMS tba mrteide tba pUat. Tkoa tbr lira proradaraa can U. 8. l*obib llaahh Rertica ba* plated a Umlt ba awd ta aapplamrat tack otbar la rtalaallaf of 0.10 ppm of bad la driaklay water, aad a aapoaara to laad. water mapply may b* rejected If tb* roacaatratba ta aummary, atthaayh a ataadard or limit b aberte Uib bv*L talu* far load baa barn aataUlahad, la prartlca Tb* reavlt* ef many aaalya* Iadleal* tbat a altdlay aral* or rany* la mor* coormutly vaad. the meaa dally lead Intake of th* ataray* Kartb Tor rxampto. talua below 0.1 ms par liter of America* adult I* about OS aty of bad la food aria* my bo twwidered of llttl* or a* *l|atA> and bavarayea. Tbla um* amount to ailmlaatad cane*. taliw* batwaao 0.1 m| aad OS mi to*- dally, b**u* tkar* to an equilibrium bctwtoa la* titul* aa laUrmedlal# ***, aad tacraoaiai Uk* aad elimination and tbrr* to a* bad reten talua* abort OS mi ara rtldanr* ef baaardooa tion. Aa perl meat la wkbk aa addllWaud 0J (rod rtpoaur* aad tba a*d for latprotad **- ms of lead far day wot added to lh* (veeay* flaradnf rantrol. U*d la tbla manner. In * normal Intake ef 03 my, making a Mai ef 04 juartlr* trlth aatlrvmmmtal data aad mrdlral my per day, reeulinl In aom* lead retaatloa. TV* indinfa, tb*r* and be llttl* roeI rotarty rerard- aafa beef of bad Inyaattoa I* food aad driah c f J' "' i ''in " *" i * ' * li'T* f ( '~i 'rfj .v ...r.- fate-iy-d.',*r.afiiV .1 ty*i,.iy..*r->**.: tt nivi'ssio* appear* to lie between OJ my and 04 nr par dig. The limit of 0.1 pt*n (0.1 nr par IIlr) of bad for drinklnf water therefor* aaema reaaon* abb aad eolU/aclory. Tha bvl apparently la not herd to meet, o the rteulti of tha analyab of drlnklny wt*r from 34 dtiea la the Coiled State* tr a mean value of 0.011 nr per Iltrr with a ranrr of 0.001 nr to 0X14 nr par ltUr. HffMc Standard for Laad In faW - The Americas Standard* Aarorialloa ha* eetaUUhed "Amarkan Standard Sparifiraliaaa to Mlnimlw Hazard* to CliUm from Baaldnal Sarfaco Coallnr Uatrrlala.' Tha atandard was tha raoolt of action by a aubcoanmltlc* of a Sactional Commit!** on Haaarda to Children. 44, orynaUad on March 12. ItU. Tha atop* of ac tivity of tha aubcoouaittaa war 11mito1 to tho potential bazar-dr to children ascii u ntiybt ram* freon tha handliar and naa of paiated artieba, tha haaard briar from toxicity of cootiar* chew^ off and aeraBowad. Tha atandard apariScatian* atat* that "a liquid cootiar malaria! to br dawned aaltaUa. froaa bmhh alandpoint, for oar on anteIra aoch aa faraltura, toy*. ate, or for intarior oao in dwodler anlu whan it mlrhl ba ebawad by rbitdrvw (a) ahaQ not cootala trod rooepoonda of which tha laod roolaot fralrtilaUd aa 1%) la la canaa of 1% of tha total wairht of tha cootaiaad aotlda tlododlar plftocote aad drier). . . * Thia atandard la wfllabb to a aadh oaa, aad la tha only atandard of which tha author !> aware which Uaalu tha laad cootrot of palnL It woold appear loftcal and naanaUt to aaaana that nay atandard danllar with tha Wad rootrat of palat. from tho vburpolot of a health haaard, would bo board oo sriaotiftc and toeboeWrte daU and obi oo tho uoacWotlAr concept that, alnply barauaa a aobatonca W "telle," Ila oaa ahootd ba arbitrarily limited. It ahoold ba a fuadmiatol concept that a tubtoanc* caa ba oaed If it W ahewa that Ita oaa for a pnrtkalar purpooa W safe, and that It cannot to aacladrd alnply bo* raoao It W cleared aa a poison. Summary It boo been dearly dawinaatrmtad that laod orrara la tha homan body without any advene affect*. oad that a toxic raepoo*# dryend* 00 eotxaatratlu*. twtlafartory k)(lnl atandard* for laod Kara loan aaUUIrked, and It har bran daoconaf ratad that Wed caa ba oaed aofdy If the aiaotiord* are und, ar*d u#l pre-forty. Tha aatotr llahmaot of atenderda la not an objective par aa, hot rather a manna of obtalalaf an ohjectlt# the pmertla* of Hamful or ahjartionald* ef fort* The flyura* pm la tha ataiwlarda have menu Inf only when mad by roauleot par**** and intarprwtad within tha framework ad tho coenprahanaira knowlrdya of tha bioioflco] action of lend. iTyure* art act a eubetltute for round Judrment. CiuiauAM aowncTCB; Tha modeot Udy who b ftdnf to bod tho diaruaaloo of Dr. Schraoh'e paper anid that aO aha farad t bnrw no tho . .prorralq waa tha word "Cuoaahaat" after bar nama. It la only right. thourh. that wa rbeuld aay for the benefit of tha few hrra who may not know, that Dr. Mayer* wa* for many year* tha bond of tha medical xrorh of tha vary esrotbol Dtrbioa of Induatrinl Hyytana of tha Maw York Stole Labor Drtnrtaaant. Prraoanfly, I know of few p<w(4a to whuea I would turn more quickly for medical adrice oo induatrinl load prnlilinu DOCUISON aw war a. wanna: L'afertnnotoJy, eiaadarda or* Idle oaed, net aartoalvaty by nun arte of prafiaalaoal' paopb, hot by by frwwpt wha, with tha bear Ufao tboa la tha world, try to aaa them far apauiol paw* far* Thia yrvwaU enow aarfaua pnhlima, . We not lojbrirx faa rxrwpli. who, ta fdotbif tha material* they artak to oaa, would tta to br oUe to ran dawn a ttet of aofay auadard* and pick tha aoa with tha hlfhaat noter, oo tha thrary that H b tofer to m than the ether*. They 4* oat appircbta tha fact that tha tray b which they wfl oaa tha auioiaaiu. ha phyakai. rhamkol aad Uo bfbal prapertbr -- whether II b primary Ini* tool, a aaareuataf afeol or whatever -- wilt nab* a tranwwdawa dUfrrvact b whether It run ba mad aafrty far a fiaao pa.p***a drtqiti ka labltoa pa.ittoo b tho IM af aaMy atoodardh. la name aubataaraa there b a wide tprend hrtwaao 0 a*fa law*I end aoa ohWh b Myhly fanfare aa. la athrra, tha rprwaf may ha aa nualt thot aapaaar* to toab raoraalrattooa b dtArult to oaaid. And Inf naye aferta are awnnf tha ontiara net aoaCy tocoepneetod ta rafrty atandard*. It la Uaportaat, lharafara, ta adarnU atapbrara to aadantaai tho4 tha ototartab they wtah to aa# ranart to a.lrrtod far aafrty an the hnab af their nap active paaKreo to tobubttoo af accepted aafrty ataadarda Klatlrf alwaya have aamrthtaf af aa atnaapl irt of nryto ohawt them, which nobr* them aaidaodiaf. Aaether by froop which tenda to totredato aatafoba into tha practicnl appllcattoa af aafaty eland* erda raotprbaa thaaa wha wtah to bftelato then bto coda rulra and rayaiattona far pniM af ao* farrrotont. A Dr -Srbranb aa wall painted eut, aafrty atandarda p realdr oaratlratt beach a*erV aad fIda* far raatrat of tha Indurtrtal ravtraniaeot Dal to rautiae anfearaaaect af lefal rerjetroaewt*. than or* neap preellrel linltottona to thair oaafulaaaa. Tho awater af oir mmptoa, fw atampb. wbteh Ml ho token la Iho etdinary miu cf bw refer r ww rat, to r.raa**attp llaiitrd -- anreeUateo to aoly ear or twa *an*)Xe* Tki* la apt to h* laadeqaato b aaaisato the rrteat aad the natare af the aaporara, perllm* brip when avrfea aa btamlttonl atpaaar* nr* in- '< .A .. -- $ "j .-i HYGIENIC LEAD STANDARD! S3 rk**d- D| A* n*t faD/ i^nHalt tW IhnlUlton* of aajnyUnf torbatfne* -- yorttmUriy tto nerd for tbU **rt U U 4ow m]; Vjf yrnfreekteml ponyd* --* ar tb# InotUttoa* of Utom- l#ff yrerrdnm*. They b m( be tmyr*aed with tto fart Uut Mtfrlj Ua4hU M* iMaalftf eedy U Um K*4 W ^rfUul ^vf*U vtw ft4*irta4 Urtr I1a IUUm and b la la^ryfrt Umil Krmaai m of anfely ui4nii la aba n mm In tto a4j4irfiia nf raaMl rvUtka la rUku for vodwra'i NM|MaUaN. KVa a wWi *t|art la oko w n U ka*i (>* nhlnnlially within Om Umh* of IK# aofety rtaa^ari na arid* need by lalmwat li*MUrUM of bk n^oift, ttk k ar< to W Km4 at ranrUrfrea rvOrarf tWt Um it n o aw*a) wliHii fcrtawa bia in00*1 a4 tto ro- C*editor of do Hiaka! ^rtvta or oibor Nkoal M- frtwv to tto contrary. Two orroro or* lavoirk In owrb raw*, fieri. It ko not atony* yeoriUe U obtain MiaU* 4*U. after lb* mil, no to yewUky *b t U< m*aa?a *M fat tonne of nfrty aUakrtk giraaj nnf*ty aUoltif* art wekiJ primarily aa faUu for rontfol of tbo todnrtrial ewrlrwn--wl oof tbo y crUctiao of tbo frony. Wtow aofrtj Urnd- ark nr* roi| Hid wttb tn n nrirano, tw tori* dear* of tojnry In tonltb la Mlolwhtd Rot Ml Itfrmn* Wtwrwa MUkaah Mttoao toW l yortaat boro no In iwy other toonrh of i*flrtno. A dlncnaola In no bftiilial cnoo b n mtol row* dooim on tbo book of Mhl Mac* k wbkb Inf motion of tbo wyotiaml toyooon anob*n no InfUfanaallr motrftoTliO lafrty aUiUarb niM. boo i nr, bo ink yor or In oak tbr fia<i*alit nor mo tbry frlamlao bo fretie* of raan) a*lathan. I wool! any Mini tbo anfrty diakk far lend yodei nine boa Mail ny rnaaAtM; well o*ar tba yrona 1 t etwee tbk la doe to tbo fort tbnt tbor* boo boon n IfanaafnN enyrrtenro wrttb ovyoaora to land In boanaaa jlaaitrk Ink yrtomrdy oyoo animal tiyrrlmalalkn land lo bo wenb tomwe* tbo foolta mnoot k ratmyoUlk to lanu oayoonrr HI nay front 4afrna of Moilanta. Oor yfaint lewd atAndard* or* rmortoU/ aaaai la oty aplolan. Tbor* baa Won fkooka Wrt, ik ahrtWft, of drrattylnf aaynroto atakaka for lb* fafmal Wk ranfiaafa. k*k on fk*rtn* to Ukr yhyetonl. fbaaaltnl and bkWftml yrayrrttan. TbtortfknJIy, M b**ld W you Ik* to oak ml fkbrtfaaa w*b yeedi. Howe+er. ano tarot Wor In nlk ihal fry ttoatak la In aaaaara nn aryferknattoa; nod. abn Itort nr* oo aonoy urbUn ki4k. 1 nakr rWWf M la *k to f* koto mImo o U af tba boko Mkari I naaifar aloe whether lay fmfa mM not bo torwytod to Inbo onrb ntaaoiaU too Morally, ak or mo i to r*far4 <bo ooaalrrt In tba aUkarfa na ma inora infell 4* tka tbry now reyerd tbr orrf all bk abakk. tWrrby loadlnf to arm Creator mliwao. at c. * aavi My ooiatlao yeotota* to abkaak far kbibf wnlor I nao bialtk now viU a yotknt wbo wo* Mffk to no nod wbo boa Woo radar Ireokoewt fnaa CaliWab ta T*im fa* no ttlaaaa Wat u H4i akUfiMMk Ik *na referred ta oa bf tbo Wmolokfik If* fawod *W ooa earreOny COO* Oderake land Wyend tbo u mI yemtowbto Itmttn In dkroaknf with bar tba yaaofHa contort with bk tbnt *ba nkfht bo*a, ak In kf bbwrra nadbal bUUry nod oiyerlefwe* vilb dortora all or*f t>U reonlry, I karritk an* tbiof tbat InlHfwed ma. TWat *o* lh*l mo m bad auffeetod to bar tbnt aW wee alfelf# Un I naked tor ta briaf aaa aaoao of tor alfalfa leo. which ehe did t fenad tba alfalfa bi, tb* Wow*d W*, bad a mneideroWa faaatity *1 load in U, aa tto* f naked brr to Winy mo aanaa of tba tm In U* y rfcac*. 8b* Wwaybl nw tba ton. I kitk tba tan. It bad no Wi I oahrd bar bow aba nak tba ton. 8bd hold aba woa tba 6rot ana to tt *y onrb Nimlf. 8ba wmt to tbo bad wntor foorot and drro water fnn tba bat orator foonrt nnd wad* Wr teo and dmnb H. Sba bna born Akaf tbnt for a Waf Una Tbia ru tb* brow abo broofbi w wbkb moulaad aboot rtgbt tooibo of n wtfH fyaw of land yrr bit* of oHoo. In Irylnf to And not oWcWr tbera nl|t( W any rofalianably to tbo drinkinf water, I naked wWtbrr tbrr* war* any land yi|wa ta tW water tin*. 8ba anld nn Tbetr bm* bod Won bQt noWr EHA yrtkatlM rtnally. they k* *y nQ af tba water ytyo and foond If f**d of Imd yty* i\ tori) Wdwo*n tb* rMy w*f wain nnd tbetr yroyorty, from tbo Hy main te Uoir bonwbkl ooyyly linn, nnd tbo trot tnlokf fnn tb* bioiiball ooyyty tin* was to tba bet water tank. 8b* on* tba In* on* oy aneb Mnkf, nnd Amnb frwi tbo bat water tank. My o*--*i*p to; Si M otifl tbo oaoMnan yrnrMoo tn a** lend ydyo from * nab to i ooyyty lino, nr no* tbera *tiH toad- ylyo* In nekn boanaa^ nnd to tbto of nay etcWbmnorf riANUN bowmen V* nr* n area id In tbo City of Cbtratfm. Valeo* I aa way of baan, K to aot Wifely yarwrtied. Wrt r*^o?rrd by tbr Oty of Cbl* rac* tbat a> aorrtoeo, waniny tb* yiy* front tbo rtty wain to tbo bnweaeat of tbo bottdi^, nt bo of toad. tta. c a m. w a a t v m.* It woold ram to m*,. to tb* vartoo* tknoo and orroknoa tbat Mn* of no do barr to defend wrkm to IMcnttoa tain, tbat neramto. irtailtobk rtakerk onrb a* boro born dtimieed ber* weald bo tb* oao Nyortftr doff*** tbnt wr weald bovat, to tbat It to an ortna! Ifwn nnd tbat H road W rwreUud, or rntbor. It ronnot W weed by a claHanat*> etoerwey. In * NkAay tnoeo tb* rttoot'i nttomry ran nol* lify wb*t tbo rayen rut* by Uklac nn rwttoky aiyaWo rlew, by footlny o o o m M tbo rnrtoao dor- tor* torlwdiny to. Aab. to. K*b*, Dr. fbUltog, Dr. IWbwnrto nnd nof tln TW attorney needy refer* to and faodao. tbnt yon ad o dwtnr't tori Ibal Ma tba rUlmnot4* oona* ytalntA !ta ran, and aftoa kw. rao*fl*t*ty ftrOiff wbol Ik aryort kotoa. tw wait** | mteirlf didn't want to (too tbo Imyei ulna af nderraWinc aafety aUadardn I tbink iky ara laoeakf valaabto, no to. Itobronb #o wet) Wnnfbt i Mar* to w*rk tbnt are* M lenyHkwitfiy, | toe* rnatknad nynlf to ykntinf ot new af ito kortaltona wben n**d by awym fe--tonal ywyk, nnaoaro *f lk danyem J yortton* tarty wanted In atrena Ibe fart tbat amatora fiNNk < [ f F > \ "i U THURSDAY AFTERNOON SESSION W m rwbrtiloU far WWI Aa imiU la Amm'i rtafiMiUci tlU|UM, Ms. r. C *4mi: Our #Ut# u Um*4 wkk m*4lr*l rHaota a wry roAp*i*L C*auUic*wr #( KrtJUi of Uki Oty of ft%luo<rt wV* li prrwfit to day, *># wry Slow OltorU* of Haottfc. W* K Wot# m tk rw>l4rrUw of Um m**i u rof^laUvM rUU^ to Ux yraiaMblo <> (vMrttMM of xtoriaii. I **i4 MW to oo4rr*v# vW#l Dr. Bcfervwk fcoo h U la kW rofoaria, Uat Uw MAC toluM M4 b* |Mi U U4mU7 mUmt (Lm W o*Mitfy. I (UM foil to rwpfy la tW nurtt mUi a fwr tMitoftU u* n^rmbf wkol to m U a plow* bop* ofcovt ibt of ft 110 **]**. If t**y oooo4 fooO la o roortrouca. fcwt rbA wo row U 4rf#ft4 (MH o 4 Mf ftlt or# itlM * pIM viu Ow* MAC roJiHTA, Oiat Urn* oot to bo oo< lo rral a 6*1,u* |( rtiU yuo# to tbo Jury* *a4 tb# /wry, tin*# afir Uo*. wfU fto4 for lb# pUimiit. . CluauuN bowprrcn: Wo art tchodskd Nrcarnr U>U iftrnwA at tiro o'clock wttli Dr, tno*4 C MrO# M Oulimu. It tbo iatnim. Uncbooo win U o*rv*4 at 1J.AS Ml tMCoUCatM Itaa THURSDAY AFTERNOON SESSION NovawAar 6, lift CKAOimx Krcn: I thoaU Kk* ta Uka thl* opportunity, u i |nwl of lU Lorf M (rin AMeriotian. ta Myna ay pprarialhai for Ik, Im profr*m which ku to*a inupf, Undr fiK I anatna, la Ikt dfort* of UuIrW Bwfifck. I kt* Ikal thaw aba on liUwtW la tfianwalot tto popart arlll try ta auk* lUr mufa ta Ik, H*!' Vo Ik* aurropboao fa. tto > *a that ya eaa to toard. FWaa* apala. Uiatlfr yvarwtf, borauM crttonHat oar at*aayptM wiS Ml tojra jroa, oo4 it ariO ba IwporUirt for tb* ,K*qnt racord that wa fcaoar aha ait afcat. Oar Ant tp*r, Tto Lad Coalrat of WsUr fnaa Mint FaiaUd Took*,** atO to flna by Ilrmy H. Elklaa. Director, Stata Diviaka f OrrarailoojJ Il/yWaa, tto CoaunoaaaaHk af Xaa*acto*otla. ,5 Fe many yrora aUndplpea and tanks for wster lflra|t her* bnii painted on tU Ineld* Uh Type IV paint, as T*t4* ! abowa, bsraua* our main Interest, especially at tb* beginning of the rnj bad paint* since. la tha pe't. bad paint* have study, waa In Typ* IV paint. ban frcarallj superior to palnta containing other Three of the tank* coaled with Type IV paiat pigments. Wert la New Jersey. Tb* remaining eight wars The prtanx* af bad la drinking wafer la suf- la Massachusetts. They varied la elg* from Tt,- Acieot amount* to cause intoibaltaa has bran 000 gmllotu to 37 Er.ilUoa gaSroia. Sarnie* Were not'd ocnikaaljt. So far a* 1 bar* bran abb colhrted by engineer* of tb* Massachusetts De to dafermlaa, lb* source of tba bad usual!/ baa partment of Public Health, by waterworks per bara bad pipe, and ordinarily ia domestic sona*) and by tb* writer. Moat asmplea war* plumbing. Previously I could bar* said It bad drawn 0<T from ootbta adjacent t* tb* stand lavariably b*sa bod pip*, bat Dr. Kabo* poinlad pipe. a few were dip tempi**, and some were cart tbat tbar* bar* bars otb*r c mm> of load la from outlet* somewhat crowd from tb* task. drinking wafer than bad piping. Even ruck pip*, aa a mb. present* a acrloa* pnUta calf Aaatpil If tb* wafer b aofl aad addle. Sine* it was deairabh ta detect very sews I Daring tb* Utt war. tb* gwatlaa i* railed tracts of bod, large aampba (400 to HO ml) af tb* soltabtlily of rad bad palnta ia tanka were analyied. Tb* bad was concentrated by ad for potable wafer, Laboratory studies undcr- coprvetpitattoo with calcium oinlato. Tbit was takra by Um V. S. Public Health Sonic* indi found preferable to evaporation or direct eitrac- cated tbat acaa* bad wa* dissolved from panel* tha with dlthltoa*. The dstsrmiaatkei waa aaade mated with rrd had paint*. Aa a malt of tbi* with a ditklaoa* cotoeimetric procedure. Anaty- lading. It waa aaggaafed tbat tb* aa* of bod ai* of known* Indicated romplrte recovery aad paiat ia taakj and alandpipea aard for tb* ator- aa accuracy af A10% If tb* had coatoat weeded ag* of potaU* wafer bo prohibited. At tie r*qtx*< of tb* toad Industrie* Associa tion. a study waa mad* of lb* bad coafeat af 001 mg/L Rawdh water from **e*ra! atandpipM which bad bora The reouha of tb* *0 analytes art aamcaartud painted inteenaQy wilk bad paiat. Tbta study, la Table IL L'y far tb* grrateot camber of which wa* begua la INI, baa Inrolrrd analysis saaiplea contained a ncgttgttj* amount of lead, af to samples of wafer from 11 diderrot stand- hsa tbaa J000 mg per lifer. 1 hart ased tba pips* coefed with Utre* llfcmt types af paiat. Tb* palnta Inrolrrd wrre: 1. Red bad la tinned oil. referred to hereafter as Typ* 1. Tbii li tb* paint which la Ut* past t u n. tvaun *r bmn baa be*a mainly ward la wafer storag* tanka. 1 Rrd bad la a phenolic rrhlcla, referred to Vmd ftsVf Itt X) * **#* MmI a* Typ* IV. This b rarrmtly tb* preferred paiat la many quarter*, being farter-drying and tappoaidly awe* darabh than Typ* 1. 8. Load chromat# la a phenolic which, raferrad t* a* E A 1 Xlag pelat. Tbla paiat baa IMlalMI IMIoliMI **ti Ml te*M MM < II toll* MM t % been widely aa*d la New England. Sample* were taken frees four gtandplpas Im mediately after pelntlng. From thr*e of tb***, sample* wee* aubve-iuertty taken at iateoab for virtually tb* *otlr* Ilf* of tb* paint. Art, right and eight year* isepertlrely. Tb* Urge*! number of aampba wag tabs* free* tanks painted with terminology of mlDlgrsm per tiler. A ssnaS number coatained between fioc mg aad 410 mg par lifer, aa approximately agual aamber con tained between 411 mg and Ml mg pet lifer Two aampba contained between .01 and M mg. On* of three, containing .00 mg pee Itter, was taken freer! a task palated about net* year ' Taie I ~ *~ l>|1d> #4 Ttatd Tm I < iwi ~ T>H IV t4a4f lM | Ml 11^4 ilnaiW t )Nm iMm| K*lif *t r ft| I* H ~ previous with the Typ* IV paiat, but atudbar taken at the tame time had a Mrtlglbb had content. Tb*** w*t* na aampba la tb* range between 44 mg per Ills* and 1 mg par lifer, If you will recall Dr. Ibhienh's pope*. .1 mg p*r lifer la tb* p*nai**!bi* limn (or had la ELKINS drtahlay water. w* Found there wee* three u s ^Im that nnUlwd oeer .1 mg of Food per filer, *nd tom than X mg. The** aampbw are *U from lank* act la arlle* aareku, but owd in aUod-by aareirw. On* of th#tu wa* tram a tank that had Ju*t brae pointed with K 4 F Klftf paint The other two war* From a tank which bad been pointed about threw par* prartoualy. with th Typ* 1 paint. Apparently th* watar la that tank bad erry definite lead cooleot- Itow tan w* nmciW thee* raaalta with th* , Andlnya of FefrhnO and Fraa*r of th* PaUic Health Sank* that load dUeolraa freely from bad taint* auck a* tboa* aa*d ia tbaa* land- pip--T Th* obrlooi explanation la that th* water doaa not atay la th* tank loey actouyh to pkk ap apprwriabt* amount* of bad. Th* threw otaadplp** texiled Boat thcroufhty war* la lnelttutkme where the daily water cewwentptlo* approximated th* tank capacity. W# bar* carriad out a few paoai atodlaa ia owr laboratory and. la paml, Maim th* report af tbo Public Health Sarrke. that apprectakto amount* of bad are diaaolrad. aapacUUy fnaa Typ# I paint- Aa a matter of fact. Typo t paiat with litbarr* added, whkh. taw aadmlaad. to frequently u*#d. yneu atf appreciably more bad duriny th* brat few Boatba tbaa th* etraiyht red bad la afl. Owr rwaoh*. coweaatad te tag *d bad diaaofead par etjnare foot of awrfacw par day. in ana- auted la TaU* IIL Tama IIL kaam *r Pawn* ttmem U4 IrbtoM (w 'Ahff IV) ll.fWffil kf t ** laff>hto Igla Ttvm | Mrf M Tm i TtV IV u 9*1 CM iM tm VM Tha Brat two Waake la whkh they war* taated la water, th* Typ* I paiat with Uthary* far* off aa aearaye of 11 mg of bad par equar* foot par day. Th* etraipht Typ* 1 point rare off baa than half that amount, and th* Typ* IV pnlat yar* off ona-twwntlath a* mach. Now If w* tak* th* atoray* attractkw af land for th* Ant aIn* month*, w* And th* rate la yraatly reduced. and It amount*, on ta aeorny* of th* Aral ala* month*, Inriudlny th* Aral Iww weak*, to .} n> par equate foot par day for lh* Typ* I point wtth lithary* added, a llitl* more than half that mueh for th* Typ* I paint and about a tenth that awl of the Typ* IV point Actually, with lh* Typ* IV p*Ul, th* experiment only ran a II It tw mu tkrea mantha. If we aaaum* th* earn* rati* af aolatbui af bad froca th* Interior af a yiva* atendplp* aa waa found ia lh* pan*) experiment, era can com pute th* rat* of water tumoerr needed to keep U>* lead content writhln aperifl*<J limit*. Swrh calculation* for a atandplp* fd feet la diameter and feat hiyh a re abowro la Table JV. Thb la a email atandplp* (about lOd.OOO ymlkuwl, and raptenant* rather aa anfaeoraUa ratio of aan fac* to eolem*.* I Taata IV. Tmaoewa or tr era earn Ctlccum Lae* Ooariaarr Nm Tw fw Ntodlif Uhl (W*M run... Ty*l rntiv in 1 vmli Ilf MMM N Va l Mkoa Wi 1 ffA Ut U wh Cl M Cl CM Cl 1C ILM M fetOM Iurn IrMO CM* It 1* area tbt ms with efl baat pelat*, a dally cemaumptioci of baa thna th* capacity of th* atandpipw win re*alt In a bwd contest, from th* point, of bee thna oo* tenth the udam eflowahto bee! With th* Typ* IV paiat, a Bach lower coaaumpelow win yletd tha aaan reaulte. With Urywr tanka, a lower Urnorar b andid to effect aa aqua] dihrtks ef tha bad, alac* th* erwe of tha tank waS* end bottom U ban, la ceewporiaon with tbn nbnt tbaa la lh* amaSer tonka. Cesewraaiy, with emalier Hnadptpm a blybar rat* of water tanweer wneld be e*ukd for dilution of tha bad. I do not bribe* that any of the** who objact to tba sa* of red bad paint la ataadpfpa* aerl* ouaiy think that asouyh twitamInotion of th* drinking water win reauit to prodare a nlynlAraat number of ewaa* of bad InUwketion. Th* parmlaaiU* Unit of .1 my per liter provide* a aubatantlel maryla of mfety for the aeaemy* In dividual. aa II ahould. And, accwrdlny to our Andtnya, thia Weal wa* not are* approached la moat of tba aemplea, acr would It bo la meat y*tasm. It ba* bees propcaid. bumr, that at* tbouyh harmful laeeh of bad era not prodneed ta tba drlahlay watar, ary lacraw** at aO la bad coseumptlcs to undaeirabb and aboald ba p*a* varied. ] ran yo atony with thla nrywment to a certain extant- If it tk* watar ronaomed by a lary* popubtloe contained bad rlyht ap to th* parmlaeibb Imf. a rarrfal etalietkeJ etady mlyht reveal autrylnal' harmful effect* to a *m*n aumlwr of IndlrtdaaU with Mrupwtbcul or other rtpoaore* to bad, alar* th* amount of additional bad latak* required to petalace (a* toikatlne arould ba aocnawhat reduced. Aa th* land content of th* watae U lowered tutwtentlaOy Uh* I my 1, however, th* bw of dlmlaUhlky return* would apply, I doubt eery murh that any I | iy i" t KiOMXAU fAINTKU TANKS ST -I effect at all c o o M bn detected, by the (Met re fined method, la ft population who** nhf nap* CaodmUa ply rontaJned .01 mg I of Weed. la rotnparlftoa with v who** water erne hbeoUtely lead-free- A ftlody baa been made of tbe load roateet of water fma etoeeei etandplpea painted wUb There an oil.er much non Important aourceo kad paint Of TO aampiee of water, only threw of b*f IbUkft than lead paint fa ai(*r Land- contained ftlrniAraat amounu of lead, and throe pifuo. One ftoch coorr* U docnmtk plumbing. wrre from tanka la atand-by a#relie. Tarta af By thl I do n<4 mean Wad. but modern plumbing the extraction of lead from panelt roatad wtth arlth Iron, braaft and broore pipe* and Attlng*. rod lead oil paint Indicate that M algalAcaat W nrratly aanlyaad tamplea of water la par quantity of lead win be added to the arerare office and In tbe hem* of on* of my cotlcagum and mj ftelf. taking aamplta from lb* faucet* water oupply by the paint If the arerare daily coneumptton approackee the capacity of the tank; and water coolee* tbe Ant thing la like moraine, and If a phenolic baee paint with a red load ptf> and later after the water bad roa for neca* Urn*. meet la lifted, a oebetnnUaUy lower rat* of lern- Tbe raauha an (Irea la Table V. j orar la aaaeatial to keep the load mmalntlM below olynlAraat leveia. AO the eetdeace aratlalde Indicate* that only -i Taacj V. under mrtnmety exceptional coodlliona, U at aO. txaa in Warm mow Pirwaui* could the ane of lead paint la otaedplpaa far pm amm. UMCmm latli ito>m 9mm0k$ Ux table water be cceuldefrd laadrtaable from the ataadpoint of pabtk health. om-- a . %om A ' *W4 IW MW AM ' UM IW la each cam tbe lead cootent of the water ia nantMAM uww. c. Mcc*X: Thank yen. the Ant aample waa meaearably greater tbaa Dr. Elkina. Tbe diacuaaicm now erlS bn M that of the eecoed. aad la ten cnee* the differ ence wae ftlrniAraat Tkeee quaatitlea of lead by Dr. Herbert E. Btokinger. Chief. Toalcotngtc Serrtcea. OrrapntWmnl Health Program. Valted an InauArlcat ta cao*e any concern. aad any State* Public Health Sanrk*. la fhrtaaU. one who adrocated arw plumbing la a bowee borauae of load coemutraUeoa of tkio ardor oncusuoN would Indeed be labeled aa ntnolit Bet re an. aaamoer a- muincaai I think we nr* gnl ikty -n cording to oar Andingo, the Wad baaard from ta aabaualial agruauat. altbaagb we arrleed at paint ia water tanka la m* lam. the agreement by eemiabat different line* af raneenlag. I think there la a* quMClm that tha nmaaat Of coarea, oar etodim wen Uaaited ta a of lend la aor drtaklag water la af algulAraat health reUUrety email namber af lankft. all la tbe camera I* all af aa earn* aecticm of the country. Skllt tome un Preeeatly, tha ISUk Health BarrtM Jrtoktog favorable rendition*. notably tbe aoftnma aad water ataadards are being lerlftlt Tbla rrrlilia la aridity of the water*, which wen moetly la the la a dewwward dlrertlea frem *1 pari* per wltHm pH ranre lift If faeored the extraction of lead, other factor*, each M higher tempernlano and chlorine content may be non prrraleut la ether arena. It ta my opinion, boweeee. that tbe moot Important factor la tbe rale of laraoeer af water la the tank. It coaid be wltbla tbe realm of pcaalblUty, ta laolaled Inetanrea. that tbe enter regularly coaumed by a girew popeietloa may ban beau to M part* per miniau. What la tha rea*an I iblad thkT A yaa knew, lead la a ewmalatle* fftlifta. H la aim aa elreamI to which then la a* tolerance dm eetoped. aa with, any. anemic. The ream* fee tbla la net quite dear, but k apparently ha* to d* with lb* rapid WitHintla* af the ilia ml from baa* atorag* aMea. It baa bees abewa by Dr. Kabaa aad nthen that the amaeat of lead, that la, the toleralod dam dally, atored ta a fttandplpe for areoral day*. Aacb la la Uu arder af 4 lag per day. Tbla It Dm toler Ituatlooft, If they error al all. weald ahaoat cor- ance dean lalnly tneolee relatively erne" aumbrre of people, Tbit meant that nay amewat alore tbla ealaa la aurh raeea It might lw that areae coaling ether token late tbe tody and atoted etarta nfteawtltV than Type ! (win wmiH lw adti*Mr for the tn- tag and reeatu to atfacto on Iba health. New where tertor awrfare. I| la eireedlngly hard te riftunlit# are the aeareee ad Ihtt maleriall They are fend, water, alf aad Ud ana emeke. Quantitating ttat t a water aapply >#!*. with a lank of comgamble raparlty to that ef the taaki *tBilled, when reotnkelleae freea the eartena aaareea. Dr. Kfthm baa ftbeoi, la aa etteaaiee fttady that the feed af lorage rould lw >o prolonged that Type IV paint Iba aeerage proa pee day token to k atoet would be untenable, according te our reeulte. 4f mg. It may rea eg a* high, beweeer, aa L mg. COMMON EKHOBS IN DIAGNOSIS 41 Hi hi <* Ikl *m S*r4 Wfan f tto P*r ttfyk *r tar# U4 ale tto C****OiIra. ivtrisi ! tiirk. tnm Us* rvitoac* ptwwiW U On Utriftt tk* ** ary a#rttai tat ttat to tad ft fraak Urd laUttk*' air** Jaaaary. IMI, wwitfti to fftfftf*. u>4 Itaf rf M^)rt*4 to W4 IfiUlitlM. TVy ar* s< airiard fr mm irrditU* *ri *|>yr tv^rft* Uec Hr mrtiamd to ta*i ft ftNU fm* tto* aad m m UUi W Vifm*, *a<r*l*d Urft qMfttitU ftf Ufti KrsM / rva df*fW, 1 M M ftftf* U It Ift * U4 abuld to fmrt4 U ft Mrnl U toy tofreiUr, *4 IW ^kpkUi Mi ttoy tar* ft M rf lippiiaf. sad ta mta dtayarrto f toad ytoortny ra tto tola *f lift* ftrd mn totoralary rmlu vVki to titata ar* ft UuU l fttor Aft ft mUrr *f (sd. vta ttoy mi Uirw|i>y 4<14mL I UiU tbi* IIU|pfU4i*|lftt4 tan Mi nitila# - *-'". v* M ttoy m isitiMi *W ton M*4itfmift yr*vU r frMpMiati, ttot tWy L m. fUMUfi; t nr** vKi Dr. /4-toift Un ft yrrfWtly dtor fit c m# f MiAWmi-i Wrt4 til typ# *4 M^n vwl4 iwvlftlftl/ amW f tto ito*c tyya Ttoy 4m tor* bn to IM fir mm MW factor to mmifti fr ftUtNIy tow Imuldii viki <mw*l tattor Um fpliyw'i Wm, yrrtlraUrly ftftor tin tonyti tin. and ft tot rf lUyylftff, aad firtlurv v* ; 4 Um to U4 to* ftvftf frM tori U tor n* ytm ky larri, f*4 iWririflirwli emaiatoft. yctiftri to* to** Mft ftftiftftl ftwft toto to** torn IN ttot ttoy tor* Nnurt iiMiyllto At. Mhjirto U hl|i toto fiyitow f*r ptoUy >4 Ttor* p--pto ar* Ufailid fim toad yrtmii yrrrs ftoUiw vwkitif ailtort ***r tortay to4 torn* f mpyiiry. iiraw ww UWraUry r** nncftiuto ififtifr *f amU toftctokto Hi** mr, m (toy to** apfciftri*! tto ftf* if r*tir* tton a nyirt f fthgitly Wad carleaC Mm4 v vriaary Mftt Ktoy to** dWytoyrd *mi*"*- I mi r*> I tiiak It U tayrrtaMi, tWnfira to myliriir raft Ml MJrWftftl toto 4rw<in4 mm *f vial tto fact ttot tto Iadaim] ydtyataaft to* to ftto toAft Ifctofit to to UrtftvtiftftJ fttocrarlttoi tort Urt tala a nrytili itarry and 4* a tlimp ytyr iftttoto to to to y*r*)jtkttft ton. Tto * teal runtotN aad UN rt ftrftn) mlHI -- ntoiirt nylintiry ipirati-- fnn vfcki toil ttoa aft Irdalrial fmna I imn tto** ar* to to<to m --wtofftl n**ry tot ***** in m4 atari mr* tmmmm la ft urtii Um Iftdridriftl to to ftkto to |rt ri4 ftf Mft to4 rrtlrvi/. It mmm fli irdrra. tofaftl ttot Ua4 Itor >4 to tto My ttoftw mV tto jnanr* miyit i*mfHy yMm j m| Iraii ftf totoftkftttoft to rrrtoto <* -- m* ftftor nniril m.4. c, Atm; In tftftd p*4i--I*C y*a ftlfU fk ynli*yt*4 ij m^ih i If yr to** toto llimr vital titoraU* nkiin nn rapidly tin vamal Tv* fwft ityinm rf ttoftr ftiald to iyyitiyralHim aad DfiD M. aufttn to Mtmt Dr. iitirtm, I tkbi miI4 to dtoapyirud to an* If f totoT toto Nr dinaib ft 4iin>* viki in i* at itat tto that tto** !* |rt toad yl--lay aad viki k aM vti Ml My rt|ir<ur* to tto 10 y*ar 1 to** tom MrM*4 to. c4 mirMif fir, W yilmliif aim m to%* iMif l ray*. . J. a. wmeummi Dr. Idutnr tw iayUM nanti ttoI ylmtoMB toft fey ft* ftnw 4mp yiftni 1 to** to* ***** **ry 4rtiUr ettokid *to tayrtoto fact ia tit* atol* 4*4d rf rfmakak aad U torhi, tto lari *f rAID *f yiy*Mft*ft ft* ytoirw vital I liiak v* adtrilttrd to taytteli nmm ruaNra Mrdka) mm 4m art (a to Htlfa aafcakttof rttor 4fci*r* ft4 tto tom 4l*ya**U to tiiiM. 1 to** mm tv* mm ftf Jftftdir* trmm r*4 c*U 4#i(rwtto vto** N4 *xyvr Um ator* ttor* k a rkaa-rto fUfftMk Ttoy C* to llUfitN vto* ti* yiyvkiaa Ifafiag tto yklr Uf 4mm art And H ywiftli to *ai* ti ardlaary VM tifl ftrtotaattoud vtti Dr. nUaf toy. I to** *** Mtotrral *rtrt4r*y to tto mm if ton f*tolet vto f*< tol *ta to vu rwnn4 frtn viymr* ft*4 |tai r**rftl tr*r*** *f to* typ* *f 4k<nik Tta to rdki aya itarry, ftad ftf ram, itarry ft irftrd M 1/nyt--iUlny. W# tor* tor* a* tog arid ** tto *4d paltolryy Mm ttot *yrifW 4Umm ft* da* to a tyrito rtk Uft*ft**< CDTA f to** mm tontilifWal *W kftol factor aad pm a yiHIr airplilipMl ftMml^in vili Uf yrtod* if 4ln(41i(y. I to** yftoUfkftl pkirrv Ul v* 4m1 frftlMa v* ftr* ft toaei ttot tto yt)4rtiN vto nin tto 4Uff- a* faayrr to ttot m ft--U f toad yitimtof in M tor* today. Ttoy Tto ftyiapt--*c UUyy rf tto laripint rfirt ftf ir* tto tom* iIWi m, u4 Itoy ftr* tto latrratot* nyvirt to ft totardraft rinakal I* ar 4ifrf*ft vto Uml yrt to4 NrMftf Ift tto toU f *- fm tto ftyiap<iaftli4*ftj ftf auf rttor rr4la*ry tvyltoaaJ ndtaftft. diian*. ItoUrta) teficUm ar* rtoiakal ydna Dr. My*r* M I v*v* Ullititf at lta today k, art ft* MUftf iiy rf ti--ai iy toctotto. Km ato*1 nr rtynUl toy* ttot tto ton ifWrt, tor fM rf riMrr, la wiki tto raarrr toradr* ytrtaWy c**rt tton tto m#4i#ft) MidnU, vrald tto avtotolk a*yrt rf ariyitartof Um* raft Irani imu rf In rrHrrU fi dUy**D rf planton to rimkal prUoalay. Tto tyayHHdiff Ift ttot yn m4 I tot# f*r ffaMrd. ftad vMrti *r* da* to toUrfirrw* vlti ti* faadamrta) *UftUr Mftwm tovtofi. Ntmaaffy, f an martnerd ymm to tto tody; InUrfrmr vrti toy flk ttor* U ftftttt |*m| toal rf IntmUaf. trvft lard* ftyin, tin* t*r1t*y rU*lW* udariim ftiluft. Nb*4 yitotoykal rtoifi la r*r adit Uras Mffir arUkllm, Ito lftor*ltai ftf ra*ffy tft Nit atiMioryt J**t a* tto ih mJ ylydrUa for Mikity rf iHd#s ti* toftdlrf if ftf yraMftft rr tto latoraUt toll* to y* 1*1* tto ladvlrlat Mr- a* | j***tlrT*d tik ftf*lac to flur**b' wri. trry rf a yiitiH, m tto l4i*lrii) yky*WUa t*ry ia Nf a tto*# diftpan*** *r* art rtofta-nrt aad fin fltft to rN4*r tto **Urv mdtral yldin ir* aiftd* *ei parrly dmtoyd iWtock* aad yearly $ 41 WATER! dirdapid irarlaaatilitr. Jnat M leaf efl ea ten this type W raw. Wtea Iten te i rWMvt #1if Mil. tO I m MX te Dim Uf tr eatplvyir. te tet fight a mm ehnaIf ptea pntealiWI c r a ix ma m Mien: Would tha mat of your discussion wait until Um round Ubb lusancrrw f Thank you. an4 olten who might Ilka to <lanaa this fartlm. I a m sorry n leal kin mIIb IM tlma. Mjr I sxprvas my apprariattea la Dr. JaluulaM, Dr. Hamlin and Um titer Ain ueaee* 7 Wa kaia ka4 oar teUltf order arraagud pawl hly lalkM appropriately tolar. I awl* tktl a mm lun I ha riruap Ullrr. Haring had otkar discipline* lurh At bad. why shouldn't tha at* torney look a I bad? Tad Wat arc, of HaMmor*. MS T. c. aarou; 1 deeply appreciate tha brevity of your Introduction, lmm. Dr. f mlrtf has nbly presented tha Mbjact that I had prepared a paper cat. Ha laarM CM pearltrail/ everything that I intended to talk ahead-[ Laughter} And ana/ I any to him, aad te faa, that ha aad I 'Are la complete armaiat ith rmpset ta tha aafaiert auttar that ha dia- A LAWYE* LOOKS AT UAO y TWOOOM C. WAim, ux Inau elaiptr point te rail /ear atteartiea ta anMa of tha raepeaeiUllttaa that raat afna the maasfartsrsri and predacers of bad btcaaas yam are daaliof with a toxic eebetnars. Tlaara are tea particular footurea that t saaU Ilka ta dtarose brie*/ -- aaa, rear liability ta tha a pbyeeu arhe may he exposed to the haaard* of bad poianalat. If t oaar ao that tana, beraase that b the nr H la daarrlhed la oaar reoipnan tlao otatotM; aad aaraaadly, to the too ala 1At public. I know Uk h oaattare have baao touched apart bp prior speakers, aad t tempi/ wont to rad an or tea portirotor pnlota to poor ottaaa* UcM. rtrst. with roapart to /ear tmpliytts. or the noplo/seo ehe heroaaM exposed to the haxard of bod to /ear afwratlena. Too oO knew that aoar cwmpenestloa aUtotra are sffsctlao la all teatao of the codon, la all federal Jurisdictions. aad by that method oe hare rammed from the held of common taw litigation dlapstea that oca/ arlM between the emplo/er aad the emple/ee. to a word, three compensation etatotea ImpoM opoa tha employee the llabillt/ as aa timer for Uaeae particular mat Iera that hate ten mads ths soh>art of cempenaalloat Is ths statotsa. Your bwo ate net on Iform. Ths/ differ with raepert to rorvengs, The/ differ eritk rvupect to the t/Jw of lajsrlM that are made roanpseuaWs. The/ differ with reopert to ths mplnamta of innsranee, the benefit* that aro payable aad the administrative eg'eoclM that era charred with ths admin 1st rat lew of ths bwa. hot behind them all there b one romoem purjauw: to provide prtsnpf compenaalloo at tha time that the la lured employee really oesde It for thone InJurtM that aro truly twaapenaaUs under the (Ivso statute. OHrtnaily, as yen know, they were designed to raonpstwals for Accidental InJurtM Utile hf Iltllu they hacw heeo amended to provide ecus pmesllnn for occupational dieeaxax. and today there arc aajy tww state*. Kiaalaaippi aad Wy oming. whrrrlo occupational dlsmatn an pot rcsoprnaahb. Agala wo da Oof had ooiformit/ with twapset to that particular ffuture t areata la acOtes sUlao we stiU have Um achedab syteaaa. uaaatag the particular dlaeaaao that b rampaa oahb -- bad poiaoolap, for example Soane etoisa deal eeoa provide UtaL la other states, tor have' ths aeealH g-ovral trrmyt bwt, and may 1 make this nmtmaot that wtlh roaport to tha adawiabcraibo of those bwo. ear fnenmlartonr and our reorto are mmiag to treat thsoa os health laauranca Uwx whether amplegrata or aaaaufnrlureca like It or ad, and t for cme deni tike It They an treating them aa health lo serases bws aad /so no get Dr. A. who wil testify la a very limited and superficial maaosr that lob Smith, cialmaat, has a particular occa* pattesial diems*. and you raa get your Rod Mwtam aad (Joyd Hamlins and Lem lirCeee aad Hot> Kehooa ate aD ths net sf ths specialists la tha field of urnipstlMa] disposes. I should ad have omitted my friend. Tooy Umt haraosa he hat testified for ana. too, bet yea get the cere statement by eome one doctor that lab Smith has tha mapaUeoal disease and la sptto of all the teatlmouy -- perhaps that laot a fair etatameat -- hart la aplte of tha weight of tha lawtlatony, our commlaebma an renting ta And, and our courts are sustaining that finding, that If thers la evtdenca la the record that the clalmant has a disaas* for whkh claim has bsea filed, then aa award la mads. So those of a* la prartlre for Inaurunes carrier*, aetf lnsursrs for Industry, when we step up to the trial tables, have mora than two strlkn against aa la the defense tf lhat typo of claim. I do not mean to belittle the need for tha ram* A LAWYER LOOKS AT LEAD tUlolM. hat ef yon wbe in piaul bin bat* bnH m aop Won, u4 1 m ropaat. Uat If * an la Iml Ibnt tin m health taauraftre law*. let' rail lima hoaltb laaunace lin. lrt'a alop tbla buplnaaa f eeOiat lint worimea'a remprrvMtiua latra. That la my miad baa toroaae a Blnontt. Certaialy ana Ulo< la tm. With impact to |nr employer*. lkt> an JiHljf hauuAlof oaft plan la alikk ta work, oaf* tocia with which la work, protortioe from tbo bauidoaf their mplo|tal Forthenoon. they an prop erty and Jurtlr damaadinf wiptaulloa for iajoriea aaalaiaad la your laaflojnoat. t aay ta pa tbal la poor nb aa employ are tbon U a Malu mpaeaibllHy to aao that Uwaa ob>rrtlne an etlalaed. aad la tbta PBlirhiraed ap I da act kdltw that asp cat wtB tfiaotm trltb Ibat etatrmeat. U Jon ahow mo tbo eaeco- Ut* trim ceacoraa blmoalf aboat tbo haaHb aad tbo aralfan ef hla employaea. I trl9 ahow ftm tbo nmpaajr akw ceatpwaeelloa Hob aad amt It L oloaptjr (aad bailaato oa tbo part of pa pmplnyrre u aoo ibat tbo boaKb at fear mark* M la property protected. I ***M Kb* to caS year attertie* ta Umbo htel doAatllnao that ban pvtl ap wttb neper! to the larm Injury." boro aoo after aft. w o an b o * onpceootlap for lajsrtoa Bader tbo toQBl romloo etatateo. TVn ban driduped tbna dirttart necopta aritb noput ta tajary. RM, tbo laabttltjr ta aara fall nya. Tbal to wbal wo alartod oat with btcaaot tbo ototatao pay a pomaiafo ef tbo wopo that tbo otapdeyee woo reraiaf at tbo tiao tbal tbo lajory ocramd. Stmdf, tbo total Inability to perform any farther Work, la atbor worda. total dlaaUUty. Third, tbo ml of aa ompioyoo tonalai actually laraporiutod from porfonalay work la tbo Wot arrvpatloa la wblrb bo wao oaaployed, la tbo admin letratio* of tbooo empoanttm loo Iboy on briny tnotod ao daauye otatatoa. Joba Smith (torn la ond boo a complaint, aad that ronpUint la art rewind la tbo boot atodkal opiolea. It to taped opva tbo fart tbal bo, Jobn Rmitb. W a poor omplepeo. Tbo ponta ar tbo rerporolloa oralart whom bo tloo hla claim to a rerporatlen aad boo eaarta, oad tbonfon ro> eweery efcoold bo bad by ktfli. "Simple aonrln. Ump-'p ytrmi," that U wbal ><mr amployaaa an and I aay la poo and partv4(n || Ip aoadboa U pap. net-pralee year nlailonabip to your o*>|deyrao and aoo (bat tboy an poicporlp prrterlod lb tba particular )*b that poo (in to than la do Sow may I aap Jt a word with reaper! ta tbo tlaUlily la Ibo cvBeumJet public T lion, alnro I bad art Intended to pat tala dolalWd dlaraaalea of a Biottor Ibol boo alnady fcooo donlopod. I win olmplp lourtv upr-fl It oo II rriatm la thief Ubella( etatutaa. Only recently tbo Coaualtleo oa Toalralafy of tbo American Medical AaaarUtlea baa netta* awovdod tbo onartmont of a oalfona Raaardoao Seboteaceo Art la tba aonral atalaa. Bo o m otatao ban alnody adapted that particular Art- I don't (blah wo want mar* lawa. | tblak wo aaod proper adadfllatrotimi af tbo Iowa tbal wo aew ban. An wo tolas to bon a fodora] Ww doallay wttb tbo iobjart ef liWlPfl An wo (ola( ta bon auto Wwo donllat with that aobjert? An wo (lot ta bon rewotloaa municipal ordiaoaoao aad ratwIaUmw nlatlat ta baaardooo oebotaarmf A ktatOP win roaott; nofulm ta ladaotry. W. ban ta Ubol tbla parttcwlar prodact to aao maoaae If w ooO It la tbo City of Now Tort. Wo bon ta label It la aaetbar naaaar If on eoD It la Ibo City of Bokimora. oad ao forth. Wo mid (o aa ad laSaitan. Tbo lock of oalformltp wttb import ta tint U a mat proUiia la my JripMol Torbapo 1 abnldoT teB tbla. Porhapa I toll It lacwrrocfly. * aad If I da. I bopo tbal tbo BalUann Comaria* rioaor of Hoahb la la tbo aadicara. with whaoa I hod toarb today. Ho waa talkiat to an wttb snot pcido abort a cornet aUtvrio, a nrawt ordlaaae* fat tbo City of ffalllmoo* doallat with kbriiat, and If I am iacemrt la Ibat oUlpmert. I tab Dr. WlBlajna ta rurrart an. Ho aad I an aid friaadp- Wo fmoowtly dlaotreo. brt that diaatnomaat dooo art la aay way affect our |w opart for each ether -- at tout art mlao far Urn. H* waa UAiof about tbla lobelias ordiaaare la Baltimore. Ho mid. "Tod. tbo City Deportment of Health la (oiet ta aoad to onry child that become# foor moeithe old a ropy ef tbla ordlaaae*. (iriat tbo oubotoaro of tbo ordlaaae*, aad wo feel IkW will protect or prmat load pApalnf* Wpfl, | paid. "Huatifitto*. la tba Ant plan, Ibo child at fear month# _ta1 nod that ardh Baaco. la tbo aorood plant tbo anther or father Who (rta it aad roada It orin art property onderotood II aban yue apeak of a latlc aulwtaac*. Aad la tbo third plan, ao autlor what tkoli saderetaadlet any bo, tboy ar* atiB (rta( to ao* lb* pndort." Tba anrol that I anaa ta dmlop from that la to raatloa Uw mombon of tbla Aaoorialiua M to Ibo roopmalblllly that la Impuaod ape* Ihom by Ibo varlowa otaloa, by tbo tarloee mualrlpal ardtaaacn that ban born and in boremvtof iffcolrt. dtal>*( with tbla porllraWr aobjort. tf yna AoX wo will (rt moawa lawoullo bored opuo ao(ll(Mm which are Irtc 1 ta eovrta bafon Jaripo Thar* la ao collikt ta tba limit tbit 44 D1SCVSSION that Jar} may ratara *a th* *4kt Ccca- faa/ A. 8 cr C, wt thrraforw you Bty wad far* tha Meat Alatrraalaf llllyutlm la nr coromoa law court* that yo* ran ImaylM. urea : Tha diaruaaJoo of Mr. Wat ari' yapur will ta U tjr Mr. Arthur S. Mma, Vie# TraatAaet of tha Atoartcaa Mutual Liability laauraarw Ccmpaay. MSCUttlOM . aarwoa a. jawaaaw: I wsat ta ual thla inuil ihairratta* aa U<trma4 Mlariat. It It aHhar W y**4 Inch aa yw*4 niaraHtln aa **4 auytorwlay aarrlraa that tha Aaaartra* Mutual haa rtaar.4 uair II *0**4 |ra4 yalinalag mm Aartay tha laat It yuan Xlaa at thaua war* aauCwaWtay. rualrlat aaty aMkil traaUaaat *f a (aw aUUta to a tsetoa ut aary ttoyl* to*4k*l ar*. Ot tha thraa luiUiat rata*. nr waa aa tayaaara to aaaM Maitat laat hy a au wha aaaawaA nthar aaaaa taatotia* thaa athun. Ha waa aat niinMy It, aa4 tha iia|iniTlia yajnaaat 414*\ laaaat to Mart Tha anal waa a wiltr aa Matyiaw* haraar waahtay aa aaaua yaiatat ataut, aa4 thta Iaa>ua4 a law wuwka at toaWlr. lattAawtoUy, I aa lartkt that a Italy totha* ahaat ratthf ay yatetaA Maui With aaat/Waa toriha*. It la ruaHy aaa *4 tha yaaMkr aaarrua at Iaa4 yataaalay. Tha array Muuy ta Jaat tt*u*aw4 ay with It Tha tail cmaa waa aa Urtiraatlay aaa fruaa tha total yaiat af uiaw. It waa aa atyaaara to tha kaurta la a waiUlay aa4 raAatoy lawr i ay. Tha au ha4 tatanaitlaat aayatar* an4 wry hrVf aiyoaan. By total | awaa ha aalM atran tha yaaaatara, hat ha ha4 aathtay to 4a artth tout ar Iaa4 (aaaaa aa aarh. Eiyaaar* waa raaal4rra4 laaafWtaat to yrw* 4arw hta r**4KI**i. hat tha laAattrial Caaaialaalaa faaaA fta lauua. haraaaa it waa 4*Moartratu4 that ha 4i4 haaa Iaa4 yaiaaaiay Thatr atolaaarat waa that It la yriaaa (aria arltaar* a4 arrayatiaaai hutaa. It la tha a4ratotaawat mi tha 4ay that tha ma/iaialli* towa a4 th* araaral atatoa ara Mt aaifarm. If aaythiat. raw14 ha aaaaa rhaallr. I ml laaattwa what K Micht ha Ta4 Watara ay "ha at tha rwai|iaaaallM lawi yrwrt4iat raalatr* raM4y. tlarlaair* nwity. I think, ta ataiaat tha awiylayir, a*4 Ta4 waa>4 ha tha laat to auf. faut that N waa aartoatra to tha axtart that aa thlr4 yarty artiaa waa aaalUUa. Tha fatartt* ayuat to4ay. If tha towa *4 tha Mala yarmit H, la to taka fa--/1 a Mila*. tot tha raw) aiitlaa rarrtar auhtayal* hla latorrat ta that Muvai a4 Maaiay aa4 (a altar a thlr4 yarty aarh at tha yaaaanl raairartor, aaathar twatrartar ar a aayyltar aa4ar tha yrtnrlyta at yradaato ItohUlty. wht-h la alt lataata a4 faryitu haa inada tha Iajara4 w*/lji* yahUc. A Itttla wua4 aa twa ahaat tha llharallutlaa a4 tha lawa hy rato*41ny toaaftl*. Tha raaaayt at lajurtaa tolny ruwyauaaMa aa4ar tha atatwtaa ha4 a aartoaa ayart 4aHa4 tha tolUltauary y*rta4 rf tha laat hall Aaaaa yaara. Thta baara b m tha tow <4 laAatuaity aa tyyaaa4 to tha law *4 waaliyaMw. It aaa4 to ha that Ikrtr ar fawr ar flat IhuuauaA Aallar* waut4 aattla alwaat aay raw, bat m hu4ra4 ar act hw44 Afly Chaaaaw4 Auilar* ta nawwaa U4ay ta Ihraa caaaa Tbara aaaawa ta ha liar rrlAatwu, hawaaar. that with th* tafl*. -Unwary yarlet ylahttlay *. th* Tula* *4 Maury IrWlai w>, It al<tt h* aafa to ytatot that tha raat at Ha Haa wwaM hla4 *4 ylataaa t4 a Uttla. to*. I waa Iatara*ta4 la TaC* itilawiaat that th* wriytaal aaarayt *4 acriAawt h*4 aiati*4 Brat to aataMyaaa th* laaWUty to aara **41* 4aa to a ya rtaaal tajary artatay aa* *4 aw4 la tha yaara* *4 aMylaywwat. aa4 ha h*4 tw* ar thraa aalayartaa 4 (rriltyuaiat than. It Mlyht h* a Uttla to* a*M/to. Than atm nwalaa naaidiaiUt Aiffarawt* to twwaa th* yimail Hilary aatlaa aa aarh aa4 th* Alaahdity a* aarh. I a**4 I* lahar thla a Uttla hit haraaaa aa May ha nmtmg tou a y*rta4 wha* AlaaUlily aa a Maaaara *4 toaa *4 wntlifi ar toahrUly to war* yaa* hy tha taari **4 tha aaara (art *( yaraaaal Hilary I arawaa tha rrttulaa. U'i taha tha yay alar toyty *4 th* yrmat Hat 4aw(aaaa *&***4 to arta* aat *4 aa4 Awriay tha aaara* *4 to4u*trto! ray aaara. Th* aatlaaa aary totwar* th* aruarml atatoa that ar* a*w yiaytay with that yrahiuM. itokw th* 4**4a**a aawat h**a aniM/aa/lay k a AbahfiKy aa MaataraA hy a I*** *4 aaraiay*. ar Aawfaaa* aa a ymaaal I*jury hi which Arafwaa* (uta y*U tawayaaaailaa. Thla yaiatlaa *4 laa* *4 awrmtoya haa alwaya haaw a touch aaa*. Far laatoara. a *** *4 aakaalaiH a aaato *4 yuan *4* ara* Jalya* to ha a yarMaaiat a*4 total AHwMHty aa4 waa aatoyaw- aataA aa aarh awAar tha rtMyiantliw law*4 tha ' atat*. Th* toaa Iwtor41*1*1/ yat aacttor Joh. atiS artaylai h la ayfwrrwlly (a*4 toalth. aa4 hi* aarwlaya aru to aanaa a4 aay to aaraaA at th* aahaato* l^al, I Waaii Ukr to awiylKy what Mr. Watora haa t*M with raayart to waaayaawawt aat Ialiw4mt ta (ta* Uy aaraHw hy /rauaulyutla* a yraaaAura aa4 thaa (aryrttlny M. Hit raw ark waa that thaar arha au* UhliahrA malrat *4 Wu4 at aa ayaratlay yallty gal ttotr toaaay hath laaay-(a!4. Lat Ma atyrtaa N to Jaat a Uttla At>aaawt way. It la th* tolawtiaw *4 awr Iwaaraaa* iMiyaay to to *.lt* winlay to laaar* caataia* ayalaat at> HAaata aaA tojarha that Mlyht W laatHhaA aa th* aaf******* aaawto that artot aat *4 ayaratlag th* baa lata*. Bat to total* Vaalaaai riaha, ar t* laaar* th* tarattaHa (artytaa caaclatlaa *4 laa* ywiaawlOA r*a*a art*!** aat *f SuyTuat faOara to yrwrWa a **(* /tot to walk ta yalta aatalA* *4 aar BoAarwrUlay yullry. It MI4M to toJ/f.1 t* wto4 ry toy caaatotwtt aa Watara' yayar witk thla tat*. It aaaaa* ta aaa that M Mlyht to mu to aatohrtah th* thraa rrttorto whlrh raart hr tort ta aataWtrk tamyrnaaMItty sf a raa* tf U4 yrltaalay far whlrh tha i*/l*/ir ay to raayaaalhla a*A*r tha rnatytaaiilta law. I rrfrt to tha |*y*J aayrat aa It auw la aa4aaataa4, *at thla (aataattr aat a( Marat* tuatyaMaaHaig tajary. Tint, thaa* M**t h* Mtohllaha* th* (aat that ( M ^ *' r . ^- -v-... I r; . mmmm nUDAY MOR-VING SESSION A tto mi toi W*4 nhftfcc. Ml wawtiikii 4m. flicw>4. UmI Itorv d m a 1m4 y+Uawt^g WuH U vltkk tto aui vu Uil M 4*4a*l f+i H iiiw i tort 4m, aM AmD; Um( to ku Wm 4v m U*4 Wj tto UJury r tto 4Wh 4 U*4 yto--tnf Ttot U Wvfclfif at tto <U*mk yrittrlyW ttot lu* <1m*m via Mflrifil U rt^urt nrli| frrrt. Ttot* an tka tkra* ajyrnfiw Out datn* Wfa) ytoyla t*4rrUka U fvftov, ai4 Om tfiUtia kjr vkkk IW7 trj to MtoUteh vWOur tkaf kan a toftat* t a (w ar vtottor tk# fejr*4 ftlpw akwll to raa|na1i< ittkirt farttor ak ;' C Ata: Talklaf m wt kaa tofey fan tto laaprawto*' ttot tt to a nmmtm Itoa TVto to torAy fair to ttoa ON wtoi> tto itarato to a*4 toi awa Mto toa to lan< itovl tkla 4U**m, a*4 tto* kavW4tf to r#Dy toiler a>4 mof to !U ^rmatiM Out to acrarata fUirmato to ttoraff. |aywt>MiU tota amrrto to all raUfMto. TKU U It tl>14 to Pmh m tto ftoiaa c m to to*4t*4 mm to ami to rartoal to ta tfltn#*# M a* ttoa|4i M to ura ycmlto tto tu rwl tortluM jtoto I ttoak tto 4to 11k a toil to Into ta |4n tto bmprtw\m. otutiuN MMtr TtoA i m, Mr. Mam to Dr. Aak To tto# vfco M to tow aa ftportaaltjr u dianua tto p*pvr* tto* ifirniw, I topa 70a way tow oat lotto aft. ':l. r r i L- iz.......... 3 * m FRIDAY MORNING SESSION Ntwwibw 7, IWI c ma o mam cwa m. WKHTunr: The pnpia ymtorday, which wa* *0 Umalatia* aad lake* Ml with lb* yrnUcaw ( Ik* wwk*r id kit k*altk u it rnUlH to ini bbdallM. Tkk moralar w* wiB moi* mr to a*idhe a(* rasp ui lk* tUU wiB lit* ear attoatlea. at but (w tk trri part af oar pnrna Bat be fore ae pit iato thlldhood pian.biro. tk*r* wee* mnl poiato tlwl JiwbH y*tordajr apoa akick I would tike to rananL Wwaw wa* aadi to tk* AamVaa Suadwd. Aamiatioa aad Ike itudud it ka> pro d*e*d fur paint to b* a**d ea mrface* or efcjerta fernmealy rxpaeed to ckrwtaf by youaf ckOim: for ruuapio. children*. torn, faraltar*. ar rooai erfaca. I would Ilk* to tok* tki* op portunity to M a; k*t, (pmlltilj, to Mufred fhrwdttek for tfc* work that k* did la denkpltf that * ftandard. I deal Ullm tkat nan? |wopl know low mark effort k* pwt into IbU arrempikhment. I know, toraao* I wo chairman of tk* Am*riraa Academy of Pedi atric*" Committor ea Accident Frevratka. Ike erraalulkai ohIrk epeater* tbr AAA mwnalttee wklrb dnidoprd tk* standard. It wa* kit aader tondlny of the problem. kl* kncnrkdf* of tke rl(ht peopk to ccnn.lt. which maided tke Amdm/ of Podlatrtc* to Uaark tki* prufort. Aad moot Important, H wa* tb* t*rkalr*l kolp of Manfrrd klmootf, tad tk* *rr*tartal Mp aad tmrklap wkkb lb* l*ad lodurlrt*. AMorlatloa (ar*. wblrk mad* tki* olandard a mill/. Th*r la aUo another lllll* llm wklrb M.ai aj^-ruprUl., anolhrr lllu.tr.Urn of tk* aorl of boblnd Ibo-oroM. rtd* kirk Manfrod turn piar*d In maa/ Mda of ladoalrial boaHk. I kar* t.fount* to tbr imli[awt af j,_____ rootrol rratrrm. Tki* I* wmwtbl*( wkkk I aap*rt maa/ *f jrwa knew abowt. If tmij Ip a moral way. Tk*a* rommaalty aaita prwrid* lafermattim ea poaaible teak pradarta tkat mar ka tamtod. partiraiarty by ckildrmL Tkty kaa b*ea dririupod la raHoe* part, af tk. reaaAry, laraety tkfwark tk* effort* Inly < pedimtriria, k*aKk depart amt, aad etkar (reap*. Tbrrr art -- or wrrr. at fawt count -- 2t rack mtora. ArteaHy. tke Idn for tkla eal*ar rem unity an-rke waa aoneatod to m* by Kaafrrd Bewditrk, About 1PSZ. tkraofk tke atadka af tke Ccaamlttoe ea Arridnt Promtloe of tto Aradoaqr, I Bret kna* aware of tk* frojumry aad cirnadam. of arrldmlal peiaealac la )t*l| tbildrea. Plumbim. of room, wae eae of tke Important pretdrma. Maafred wa* iatoraetod la y dmriptioa of tb* umal ctmnaatoara* wf a two- or threw yowl odd child awaOewta( Mat aakaowa amount of a teeamoa keaaokrfd product abowt arhea* toxlrlty tb* attoadJaf phy> alrUa bad ae kaewlodf*. fa ear dlarotwlea, k* tkouybt tk* aor.aoary lafermallea kal< aad reald, be tmtralliod and mad* ttaiUM* to pky*(rlan*. Tki. waa tb# ymt of tk* ld*a wkkk deolopod lam tk* poke* coatnd cmtor. Tkk eewa*la afford, at* tb* oppertealty to arkaomWy* ear tkbt t* ye*. Manfrwl *' k*it a. oar Bret paper thl morataf. "Tb* Kfforta of lUaoea and Tornper.lure oa Childhood Plumbtrm." by Dr. Anna M. IU*t>or. Amwiato Prufom^ of P.nrtrmmental Medlrlne, Tb* John* tlopbla* Ac bond of ll/rka* and PaUk H*ahk. BalUamra. imCTS or MASON AND TlMPOtATUKI ON CHILDHOOD nUMfttSM r ANNA M. AAfTJBK, ScO. IUv Ww of UtAn r* Baltimore Otf Kh U Dopertowwt1 Am ehowa Uut Wed poieoalag la <UUm baa a marked oiaocaol dietHbotlow. wllb almoot all of ; tAo wa occurring b(nn Um mealhe of May . aad Octobar. Mart of the cam la tfca BaUaMco tdf v*n dleganaod by pdUlrldaH la ml*: n> BoHImoco boepluW aa the baale of cUalcal QapUoa pi** Um4 Iml aboee too aormal nap*. AOialmi by tbo Hoaltb Departaoat'i Wood load aaatrtk-al oorrica la addlliea. a Add worker from tbo Hoaltb Dopartnoat Halted tbo boom to detocmlao tbo eourco of tbo had aad to obtain ooTopIo* of IN lacrtoilnatod material for analroio* Of tbo TM cam which tbo Hoaltb Drpartawat iamtipated betwoeo IMI aad 1PM, tbo NMjactty wind ameop (UUna between oao aad tbroo pan of an aad were altrlbotod to pica aaoocieled orltb tbo tanotioa of load palat. Tbo cAfldre* can ckWfly from faaUUoo bl tbo tower ocoaooolc do tool aba taoldod la old baaoao where tbo latorior orood aad plootor Am booa coated with load palat. Tblo aoaoaool dla. tribodoa. which b abowa la Figaro t. baa or- oarrad otory pox wfthoot eacoytlou olaco tbo hrrootiotioo Aepaa. ^t*0 POtSONINA IN CHILOOtN,ANTaaONC at to MM " \m u Jill h atm w o*o h o w mi o i o h h m A olnllar ooaoonal diotHbeUua boo booa re ported for ltd caooo la AC ImU,' Its caaoa la Now York.* AO caooo la Phfledeipfcle* obd XI caooo la CAkapw.* Aba Blackmon* qooUo ootoral Japao**o aotbecaaa-mentkmlof a loadcwcy of load aatopboUtla to appear durtap tbo mawor aad aad/ lot la tbodr cwaatrjr. la a reeeat atod/ of childhood load poltoalap. parti/ mpportod by tbo Load ladwotdoa Aoeocto* ttoa, Cbioetad obowod that altboopb tbo cAHdre* roacbod tbo ambutotory aad tootblap an at al aoaanao of tbo /oar aad Una ceald bo potoatlaSy oapootd to Wad lapootlon. tbo acoto pwcepAato* palb/ did act dteeiop la aa/ of bla SI caooo aatll tbo Aral ooaacr foUowiap a tbroo mualb period of potoetlal Wad lapeetiow. Tboa It woald aoooa that tbo cbnalc lapootioa of load la precipitated lato aa acu opiaodo by tom factor aaaaclatod witbaowacr. la adalu tbia ooaioaal pattora of load pillca * lag k aot rridret. probably became of tAo many taryiap factora which affect edeha. Kehce** fooad ao acconalotloa of Wad dudap.tbo newMor la bio otporiaoetal aabjocta oa a AlpA load latake. AUbauipb tbo roeceatrattoo of load la tbo artot waa blph la tbo owmmor. too tofat-iwto# Wad nnotlow darrtaaod la eaoodaUoN with too docroaao la ortao niaaw. Tbo omman of etlppWd orytbrwcytoo iarreaaed la aamstor. Oa too coatrary. IlotmnWt** aoted a lower tore! of otippWd orytbrticrtoe la lowdwapuood todltidaolo la oaaamor. Hiibnuod" reported a oAarp lacroaoo la tbo raxewtraUoa of Wed la tbo artot of bodwapoood wcrioco do Hop oitrtuly Aot woatbor. Blare adjoetmewt waa aaodo for epedAc prarlty. tbia Incrooao could aot bo attrlbotod to a mere coocowtratod orlaa. IforiacAi aad Tabada" obowod that aeratol hoaltby ponowa Into a blpbor blood load coocowtraUoN la wapoor tbaa la wtotor. SbM" aotod a lowor lad* doaco of accwpaUoNal load peitoolnp la iinaa tbaa to wtotor la rarioua ladootrloa la Mol* bowrao, aad aacribod tblo dtotHbutloa la aa la* creaee la Wad omrrotlow la ooroot dariaf tbo oumaver, Oa tbo other hood, whoa bo latootlnlod tbo orcorrowco of Hnptloul load polooalap la rttoiw* to climate. bo found Ual la poraoa* wba Woio an toting & mg Wad of (aero per IItar of artae, Ibo parcowtan *bo bad rllalroJ tymptooaa of Wad peUoalrig waa pnalor Iba warmer too climate Tbot the data fall to (bow aay (War* Col tread la adult Wad poiaoalap with loaroa. Tbo (oanwal dlotrlbutloa of Wad polio*lap la f { -in..;-- ...; -'-< ?..l a.,.--. UlASOSAl. VAIUATION IN PLUMBUM 47 (UUm bu bean attributed U nrlw factor*. Kiposur* to tit* (non lateoa* aHrarioUt radia tion from the eon la IB* (timmer *>d tb* leeulltag tncren** la rltamla tl ha* b**n tb* factor matt prominent!/ Implicated. Bhrtllng and Hoop er1* Migrated thU theory cm th* baai* that rltamla P InrraaMO IB* abeorptlo* of M Iraa tit* inUctiaoo If tlx diet cooteln a high calciumlow ptvocphorou* ratio. lupopoet u4 kbit1 tooted tbl* Ihoocy la otpefiaxnu cm rate. Aalmak which wera fed a dt*t eoatalalai had and *m *xpa*d to tlx *aa or (Im aoptl*m*atery 4a**o of rltamla D dafljr. teat woight. bocam* ID or died, wh*r*aa thorn gleta Wad bat kept la lb* dark without added vitamin D ahowad wlf ratardatloa of growth. Added support I* girao to thi* uhneWM rwdiatloa factor fag Ch* do** parail*! b*twa*a th* tuinrtl diatribotioo of caaoa aad th* moalhl/ variation ta th* Latwdtf .of aatlrachitk radiatioa from th* aoa la temporal* climate* * Although th* iaerm** la okrarioM radiatioa map aocoont for lb* rammer pal la childhood load rot**, then* or* mo b* ran* tin* to doobt that It la th* oalx factor btthtd. ThU thsory dopoods oa th* aaavsptloa that th*** cbttdma ka*o a low phoophnroa* dl*t aad'or loch a norma] amount of vitamin D la th*ir dkt. Although ritaali D lacroa*** th* aboootUa *f load from th* pt. Sobol aad hi* co-worh*taM rtuwid that rltuli D had no *017 nulad offoct oa lb* i cuntmka of load la th* Mood If th* 4Ut tar talaod a hlfh phophiru* low calcium ratio. With prepared nUtk fortified with rtUmia D ao aridoljr tund bjr lower larooa* famltlaa a* a make Mart* of food for thotr children. a lack of tofirlot eiteJel* D aad a low pboopboro* Utah* would not bo *xpct*d. Purtheraioca. oad*r tom* roadltioao rilamia D larroaao* th* deposition of th* Wad la tlx boom. Another apUaatio* which ha* beoa eugrwted lo *i|>Ui* tbl* arenas] dlatrihotkia U that childrea bar* men eppurtusit/ la numnc ta chew exterior palata, which geovrail/ cmtala atom Wad thaa laterioe palate However, data from th* Bahliaoro Health I>ej*rtwat aorvojra Indicated that Indoor objects art Uw chWf aoorr** of tb* Wad lagewted. Th* other Importaat earlranmental roadltloa which ha* been suggested a* tlx factor ropaallde foe the aeaaotul dWlrlbvtixi of thee* arete Wad putaoolag caa*a la thildreu U th* lacraot* la oorlroanxatal temperature during th* Mamtort month*. Ju*t a* ta th* <aa* of oUcatioM radiation, th* month]/ diet rlbvl tea of roam In Italllmora follow* vary tUmtiy th* ntoothl/ mailmum temperature ram. A tew iaroatlgitor* hav* rep>*led an lac ream! uarcptlMlIt/ of ani mals to mo m drugo and chxnlraW with exposure te high aariraamental tempvrataro* or with a rie* la lud/ temporaturu."' but ool/ thraa paper* her* b**n found which raUt* tbl* factor lo Wod. Blackman* abowad that rabbit* which war* subjected lo 17*C following a *ereo-wa*k period of *u bru Laneoo* iajerlicxia of Wad. dlod within 102 hour*, wboraaa thoa* olmllari/ lai*ct*d hot kept at room tamporaUira nuretred. a* did control rabbit* at 27"C. Th* bod/ tem porator* *f rabbit* at *7*C boa* I* or 4*C A ***acuta! variation 4a th* tuacoptlbillty of rabbita ta nbcutaneoo* injections of Wad araa found b/ Ccrmuth, A d." th* avorago lurrtval tim* ko ine much ohorter ia oummur thaa la wtatar. On th* other hand, Xapoport aad Rubin* iw ported that th* npoour* of rat*, which had kaa fed a high Wod diet, to 40*C four hour* per dajr. had a* apparewt *d*ct M th* aaimaU la apit* of a ri** la rwrtal U*np*ratarr cf 1* t* 2*C tiprlmanh an EffacH *f Txfwket on Imi/f b3#f ml laboratory Aninwlt to Uod fouonmg* Bocoooo th* ultraeiolet radiation thaouy did |(l| Mtfli || |J|qi|(| tipUiitkt |f ^ miont diatribution of thaa* childhood rono and t ocaana of th* frw aad rondlct^ag oporlmoatal data'an - th* offoct of onrinooiaml*! tempacatur* oa lead poUoalag. a aaria* af onporimenU wan oadar taken la UtU labocatory to atody tb* otfacta mi oarirooaxnlal teoaperaturo and kuaaldit/ an th# ,' . ao*c*vtlUUt/ of laboratory animal* to land pot* oonlagi . Mk* war* u**d lo moat of the** op*rlwnta. although rata wwr* lasted oecaatoowBy to cor Ann th* reaulte on th* mlc*. Th* two tetnpwm* taro condition* atodiad wee* 72*r arith approxi mate!/ We relatir* hastIdit/ a* th* normal expeuar* aad M'F a* th* high tempeeatur* ax- . p>xurr. Ia aonx rare* th* humidJt/ wa* kept low ia th* high tmprraturo chamber but la moat af tlx e*perimenu a homidlt/ of tt% wao and. Th* bod/ temperator* of th* mice varied ran- aiderabl/ la both isrifoMwlA but th* rectal temperature of tb* mic* la th* hot rkamb*r* did act ararag* tnor* thaa li`C abov# thoo* ta tb* normal vxpoaora. la th* Initial *xp*riaxnte group* of 10 to 20 mlc* w o t * npeaed cuotiau- wual/ to th* two temp*raturm for threw da/* before and If da/a after iajortioa with Wad. Th*/ w*ra Injected either lntr*p*rHcuxaQ/ or lalratenou*)/ with a *lr>gi* do** of Wad acetate or aliral* eufflcWol lo raux death la approxi mate!/ 20% lo 40% of tlx mie* at TtT. la nr7 *ip*rtmenl cootioi talc* ete tnaintaiaed at each of th* t**t tempera!area. Tb*/ w*r* In jected with sodium aratat* *r nitrate In naeunte *t%b w*nma Mi t f*wn tW (f ft f*o * 4 ' U wAKTJEJt a that tha w UIi or nitrate cencwntratloa craa Uka man. dehydratlea waa produced by reetrirt- quintal to that In tl> ta4 dona. Tba mta at Ing water Intake tadlng ta a IIS low af body Or# M'P temper*! u re were compared with tba weight over a three-day period preceding tba mica at 71'T la regard to total mortality daring Injection of lead and era* maintained for three a tw-o-wwek (mat Injection period; latent period, daya after Injection. Dehydratlea rtgnlArantly ta, tlma between Injection aod Brnt droth; and larreaaed the mortality at brtb teat tampeeaturaa lb* average eurrtvnl tlma, I ,, Ore tlma between aad baatened the onaet of deatha at high leenpern- Injection and daatb la Ut* fatal taiaa. The tlma fare whew tlra tad waa Injected lei rnprritonewfly, of de*!h a lain aa tin midpoint btnn Or* but had ta* effect when It waa lajacted Intrn- tlma when th* aalmal araa Uat obaerod aa llrtaf . veniuuly. aad Ut lima trim it wn* found (tad. Cadi ax* After determining that blgb earlronmental parimanl araa repealed aaaaral tlmaa aad lira - teenpeentur* Inrruaacd the awareptibillty at mta data *na roeohired for gtallettal traatanat ta * la acute tad pelaaalag. a tecta af experiment* datarmtaa if Ura difference* war* rtgslBrant. wa* pcrfuenned ta atudy tba effect at hlgb tm* Th* axpnaaro f Ua mica la Ura blgb tempera- pentorr am chronic tad potato!ag. Than* tara Inmnaed th# mortality elgnlBcaatiy. baa- chronic cxpcHmenta ynUUy dapikeata mort traad lla onart of daatlia and accelerated tlra dowly tha condition* exiaUag la tba chlldbaod rata of dying. Tlra effacta war* mort aaiW cnera. Ia than* experiment* the mta war* ia- Wl tla tad waa Injected iatraai wnyety Uwa Jcrtcd InlraperilooewUy alx day* per creak witb wtran Injected lalraparitoarolly. SJaca Ura anna nmaOer door* af tad nitrate than thoae weed for raavlln war* obtained with latravenom iajec- tba acute experimeat*. Control mta rwcuiead tkaa aa with Igtrnperitonrol hOwtlna tW la- cempnrabl* doacn at tba aodiam nitrate. Tba craaaad nuacapelbiltly ta tad at Ura high tarn* anta wart kept at normal Umperatarn daring paratwro raaaat b* nltrtbatad ta a aroaa rapid tbe Injection period. The tejeettaa meet com abaorptiew of tad from tlra parttoaaal rarity. tinned anti] Ur* tad group *hawad a ran*latent Tba daratiaa af nymn pencadlag Inject!** might tan artrkb wa* tuaafly between Id and of Ura tad waa rartad ta a aarta af experiment*. St day* aflat tba bagtaalag of lb* tajarttmw. , High taaaparatara bad Ura aama affect wtraUrar Half at tba expertmewtal aad ctwtnl mta wart Ura mta war* ripened only ana day baforr In tbew placed ia tba high temperataro chamber. fection ar far tagwe pariada ap ta M day*. abaw- Mortality waa *igwl6caatiy higher and hrteat fang Ural aa accllmatixatta aocwmd daring thU Urn* algalVantty abortar la tba tad-injertad period However. tba atfact waa graatar If tba - . mta wpiud la tba blgb tamparataro tbaa ta awpoaara ta Ura blgb temperaturo began im- tboa* krpe contlauuualy at tbc lj'F temperatura. medlalety altar Injection of tba tad tbaa tn The pbyaMogical marbaalam raapanelUa far tba expoaar* preceded tba lajartian. tba higher mortality aad tba meet rapid anaat SIm* cbildraw may ba expoaed ta bot daya and at Unee* aad death ta tba aka aad rota at cooler night*. nevaral experiment* am par* tba higher tempantaro la not dear. A number formed la which the mta war* expoaed ta tba af peartbiiitle* can b* tuggeuted. Tba larraao* blgb temperature foe early eight hownr each day. la body temperaturo may have lacrewired tba rata Tba rfrrti of tba blgb temperaturo wee* mart at chemical reaction* la the mta aad tbaa ia- lem under tbene cooditkoa than wtrea tba ex- creward the rrartlon ta tad. but the magnitude power* waa eaetlaooo*. Tbl* rveult may aeplala at tbe trcnperrtr.ee effect wa* aowaideeaUy gnat- why lupopaal and Kokin found aa affect of blgb er tha* would he expected on the baaie at the temperature aw tad potaowlag la their animate mad riaa ta body temperaturo aad Ur* nauat which wr awprwad to tba blgb tamparatur* far Qm nbr af t* ta Urea which la rbaractarietlc early four bavre par day. for moat rhemleal gaarttaa ta tha body- Tba la areal af the experiment* a blgb humidity baaal Bretebolk rat* ia the mta probably wa* waa aaaariated with tha high temperature, ia a Inrrraerd by exprwxro ta tba blgb tamparataro. few npertmewta tba effect* af tad Injection KlterlneM* are now la pragrana ta detarmla* were roe*[erred ta mice kept at HT US Rif If an Ifwrea** la metaboik rat* produced by' with Iboaa kept at H`f US Mil. Tha reaitlu thyroxine lacroaaaa tha auaraptiblUly af acta Indlrated that hemidlly waa murk tad Imporlaat la tad. Klnc* tha mta at hlgb tamparataro ant than tba dry Ml temperature. Thi* raauit wat ta* food and land la ta# tarn* weight. It waa not awrpelalng einea mica da not aw eat. thought that Ut#** fadore might fewI ribala ta fleea ,ht children aw*| In hlgb temperaturo their greater euereptlhlllty ta tad. but experi- and may bee*e dehydrated, II aeemad perealhla (wrote performed by Mrijuary*1 la Uila labora that the aewaoaral diatrlhutlua of childhood raaaa tory thawed that roatrtcttaa at food Intake did aright be allrthuled to dehydratlea rather tbaa art tnrroaa* euweptIMlily I# tad poitoeing. It la the blgb temp* rat ura. blare mta do art awaat eerwed proiwbl* Ural Ut* mta at tha high law- I m fdKddfifeAMfidSBkih&S ''i -`^tg Ifr'iffiftrir'iiiWiriri r' i fi ir'Tn ~r r i''S " ~ !r'f :'iJ-*i'i`- - - SHASOSAt. VARIATION IK O-UOtBlSM 4 pnltn Bl|h Ik KtnUti Uaa M tko tloM t oonaaol lumpurotuiu. ThU theory *M touted by cet&porinf Ux uriw and fic<l k*l currtlM In r*U it 72'F and MT turapunlur*. Tku da tumInal k*x ukoxrd Haul tkr uni mala *t Ux hlyk tutnporolurr eurrrlt-d alfnlBruitly boa bad la Uauir miix ow a purl'd of 14 day* foUowtof llx telnttxwM UJorUoa of bad thaa lb oat tab kupt at JJ'f. Tlx durruaau la tbu outpot of bad la Uo u Im aa probably ralalad la Ux bwar total aria* nlux, alar* Kukou* ohotaud Ibl Ux arlaary bad output par nail of tiax nrM ta .rcordoiaro witk Ux rolaaa* of watar oimtud by tlx kidooya. Tlx total facal output of bad *aa aba .ooararhot bao at Ux blpb lutopmtara A aubbr of otbor oxporiaaaoU an rurrraUy ta procruoa to taut torfetu otbar Uxorba okkfc tolykl arrooot for tlx inrmxo ta aaaropUbility of mko to bad polootalop at klfk trtaturatora. It la kefud Uual Uxaa oopuriaxala arlfl brlp to rtplaia Ux aeaacaui diatribe Uoa of rblldbood nua m.yapfcy t a a loom. . I. c u m -4 a UI 1at tom i4 V r. K Umk j s W fbkMtsH t CVW* t4 ft*# Tp4 r% m t 4 m M.na iwc 4 9U0mm --4 rw< U4 fhhd mI f a# r*^ iMMit hUliit i% i. fUi MtM, Ml. & & ft llbabi mIT Jimim fallal IfUit Onto i JJLMJk. (Itoxa M Ma ft---- to ax *d M q. Ml. f 4. 4 (MBA Ml K t iMWNl TW IlflW fWM to U| Manx m Ml i m it! >tapatoaM ItoM * bd AbtoflM a4 > loaaii i a4 TV-- --it.* w to* h>|i * m4 1W* m-- d Ud ft ! < 4 fd d fa IftH. IM to ft to *#< 4 rMu. ft llrma K Itadfto, ft ft It'***' Mf ft V. tottoll fttfp'towtol todiw to# Mm--m W Lad 0*pMito 4. M to**. *W T**- ttiftftt. to I >M*to*1 Ml Mlntolif * Urto tota< d *d i>4#1iVft* IniUltoito ftf--* to*#, fd r-4 Mto IM || 4 t*-- --------`----------* -**- - t II I ft*w* td 1 T*l*d> Hill# m M IdtoMl Ud f>* -# (tod rt da# J !,|H, |tto4. It ft O o*u Idtottol ld Mm>ih to fatoito* to ft-- 4**> I I I do-- *4 to*4 4 t4 I tot. 14 ft N ItuuiM td | I ftti r* f-- d fW* to 'to to*-d-- to4 /do* to .** tobMtol M ill. IM li 4 M r\*44 ImmI t#-- to to* iMtofitl* Bifi to* f-- to-- d to* to M *ox da 4. to*# lift*. |M 14 to Mm Td fttobMl M*d d l*d M.a# 4 I to-- rvatoa. *d tw.11 ft a* |*d * |4M |d ft-- 4 Mi (4-- Id I to. |to II 4 4 h*at* TW tto-- # M Trii tl j to fttod 4i-- it-- #o* H MV IM 4 ft > * -- ft 9b "W- ft#-- if ftoHooW--abd #* ---- I-- d* 4 f4*-d IM Mb 1M4 t* f ta la*-- Id ft ft--# TW |4*f 4 ML iMI<aapb o*dt I* ** T-- d l*Mtaal Wad I--* to liitito 4 iWa *d ft#* fWa* M- M to ft 4-- TW ftM* *4 f--fiitx **4 ft* to--* *4* laatlbtp ad ft--* to I-- ft * --* # TW-- *-- to TW 4d-- to---- to.*-- d Hf#baa* m 4* ft 4* Hto ltx1l Hkliayapky (coal'd) TW Mto d fta*rtot#d |M a to TW Ma ##-- IM CH All M a M vrntanjrr: Thunk ytx *ary murk. Dr. |Ut>ur. Tku dlaruuuloo win bu cpuaaod by Dr. J. Julioo Ckluolm. Jr, AuluUM Profaauor of frdtatric*. Tho Jokaa Hepkioa fbkud af Molt> Ctoo. OtfCUSWON aa. a. a nuauu. m May I cuoaroiulete Dr. Boafjur ao mm amt tetufeuttn* atuaruotboa. I akuoM uku Irut w xoykaubu okul uka haa aab but tka rub of - - mir r X proloriac Ux aruU maalfaolatloax af bo4 tatoabatauo to rfcibrro. rtfrn t to *u tku mt.ttx.kiy Mtua MMU. lorutlx af M laiudx, oo* xut of onto bo* ixykab yutky X a pm. af it rkiidruo. It coo W auuo tka* rktMm axy Xoat to* tkruuka( tka wtolar mibal anunat tUoumi. but Uxt tka bnat af amour pruotyaly prariptutm arutu aotoykobfotky. TVmo lau ora orB uoyp.rtuf by XA--al cixtrul kbturtao llolar tb. laHatk aapartaxalal rialltixa, M oo* lakyfiatxo rartululy 4o aokaaau Ux U*tatty af kaf. Hur rayurtataotol auo.ilixa ra*ain axMaaot X urOrf U torotuX ubtyaWart UlaloU M>OO appltal X ttokal att ,11aoa. Tka 4apw af lakyliotbo pralorof roputioxotaHy X tlx afao o h --a arm: oaxaty, o baa af oatrr i.ulialm X UA af tmfy mbU. Burk aaauao aUba af likjlaatlao axy auapobal!. uo.aoau tka tomlrMy af a ouaokar of oaoX. Tkb wuia bpx af Itkjlratlau X rmruty aoauuoturaf cixteolly X aoata luol Xtoab utanmau atrottu aota mil oamau oa* uauto au matui m Mutt lutamautu TftWWCft ftftM* _______=r rj m __. U1U^ t....- OUa-m. --- - p-r-- *- - - ~ - ~~ - fcnr- i ? "to* Er xoaaom# ;*t lrri*rrnJ tofttotto o *1*T X aoo amt ao. auo W .mu X xmu uut u bu M U u. u pauu utu bna. I am tmu aiuX urn au x I x. w au* o **. aa a. uxo to ax X . a* a --.a u a. aui au aim ! tau. fU.u am mu w . a*, tw xm X ot to, o .mUiiio iu um H. a. .u u. um U aU au** tx amoi X uuO uu tu. U...U. U X* .a H..IU u VW iium. UO* X mlU-U.au Tw N*iU X UW main X OU MU X uu aau *W miw X i.lnhlai X --..I X IXU Ou - . rr *t WM X Xa imiw .i i i X Uu .ala . imII U ku a.-a f-a-aU a...n a U U|-mU X Out mU O. I* .m *a.u> u Xa lU-m id ah 11!*l mu W U-aMuUXUU H..I.IIU bux rw.iux U H taaot SO DISCVSSION Ta k a 1. Du l t racAt, tKirntm or Lia o im Catuoow ftmaot ana Arm Kuaotru. or EanaoMiEMTAL totva nr Lc a t * Oh NImAm # Mtohr* tu. * NtoOH tv -r feu** LmJ t>X|N Tym U III Al Nm Dtdtf Itftnil ti MtoiMtil TUitf TrM- LUmIU At Hu m AIM fin i ii Tm 1 Al Ra m f*torM ImM* wiN M CrtiNl Al lUomr 0wli fimw 0 1 M M 44i tti M UM AM M ItM AMI M tm Ul m UM MM feA) AM * mi (M. AM MM* IM ASM. %M tMf . IM I +mm II , l*M| I Awl4 W Ml toiwtol U Um w U Ii --rr fcly4f<riw Mf U (iUi VMk ilnnUii im tW mfc* ! i<rmn< U*t k* lit nlalM; HktMWmk. 8ma Ii ImIi fmlM ttM Ur* Mirk> f ap 4* Ml fcM| 4* lartMikM 4 M/ M^rttUrt la napan M daap la * Ttfiiantal Impnfan m 4 On Mi--. CMMm vtth mm U4 MMOmi Mm iimil V--rr- lam aalwa 1M7 ttphixa an--In --iilfeg r caaniaHa artiHt/ m a riaah arf tWtr iiiwiiiii i<w *< hm 1 >< *4 *< M mm tv ** two**# >*< m t-- iw 1 *M4 mm a h * *4 MWfi 4a *4 M WAliH #H A( * * -- rJ W4 MO"**** t*--4 M M * um* >4 Im IH a til m M lN f t4 M n mM **AM * |HA TV MN NMM aMa A Mala Ia4 aatvrlalaallTt t mil year mmu m W Di. MK> Awn- Vm M b Mmm Mfm to kifk imln--wtol Iwiftntm towwit M taaVMy U Ika ton to took tractor t|n tou M toUrmMleal a- |mn to klyk Iwrmlm. Detinue to beat miwi Mr ovyiato mm* at tor titiamno to (rat Ik* Main at nrim a token vto km alattot tkto (tolto, Rn b tkrae nyntotobl alnnatlam fuild tomriiatoal Iptotow to rkOtn*? TWr atoaatou a ato* Ito) W irrt4iinr art to rfeotrm vka trrHc* into tofirUton tofricf >< lyto u toeunit to<r UtoM at toi After (wlnpl r i ri* t at natiiMM fmr Ika arvta amtofnUttoaw at toat U'oiMaUaa M| totRto to rack a rkilt toi--pit lira at Ik# aeeeaa at Ika |aw. Tha alter rttalrat Utoraturt to teplHa arttk Mk maria Stem At atom! af udtoun, ckraato tocDe Bla............ kry ran to rklltna. Aral# toat petoeviap prortyttatot to tkto toiar kaa Bkawtoe kantoa run. t>r. hajir InlfMt kar nrirtaitoi to kyyan Ika rato at tolaaUaal akaorjttoa atak-aOr. Ikla to a aal kafertaat taator. Arato toat totockattoa arran elateat rartcMraty tailat Ika earnmer to rkutraa erttrWf relief bat. Tke aa>r rrrnpvlait aaaryUaa U tkto to Ika pneevn at litoto Want JM limait I viB pmare* nai tala la Bhtotrato tkto la>rotcei atlalral patat. Tkaaa tala to Takto | van **atat fnaa a yraay at ikiltna el at vkeai vara ratratlay kitm.1 aawaato at toat to Ika ferae. Taa vts tiato Ikal Ika ckOtna vka karaaia M van tkaaa vka vara retie* tke Utfer alaaato af toat al Ika liiaa at tkato Uiaeee. Vkaa Ikey rtoervet to tkai/ Wia.1 Wat aara aa toratI* eelte# toat. a# fararraara a/ arato ylaaiUna reaaltat, aJtkavak tkay vara Mitt elyaaet la Ika kltb rertraeraratel tofererelene at Ika Naan, Tkto M**tal t rr Ida iMfim 1) nytaaeata telly fad at fatal aat pteMe*. TV* iMfi Uaat toat aatoavtraUaa atow ika IM at fair vaa At *| | IM |M at Uat AltlMfk tofm|tia*tk ka vaa kaayltaltoat la fraa.at fartkaa toat tkfaMtaa. Ka aaaar U<*a* m. Wa att/fWata a top fart at Um kutifnt to ear itonpate nevlta* to SEASONAL VACATION IN PIXMBISM St Kas o mm. v mk t o i w tax ctanoaoammai o h m OL*wa II VTMiam ACVTf UM mioxu v a o u t im iii (l o miia a coaceniuTifcf o >im run naa arm _ acvtt u a o wnmuroi 1 I ...,,........, -J & Tfc* iiiml f fliiiU froa >i|mw ycW to tto *- M f Sch p*UiU it mpm*4 4mr* toft tW nin<if W tki --mmtr to Wfk urtiw' mmtmi Ufmtm u4 torimi atlitvMit Mtor Imtolto, tot 1W7 4* ft* fcifi ac%Mf ML tiUaa Wyltyrto muWtoa to ftrinly ittnpi to toni Utnkaun. 1 itnli Utoli tfcto *n *SB ftftattor fnMt/al toii to **4y. wr>#i TV* rtft4fc f titit m4 f Rfttoft m4 Mkl tUl viu*a 0 pUy* fta mi*, rvfirrfU* f tW 4td, to iurtM^if tto lUirntt f 1m4 frea Uw iMffttot. S44 ib 4 U> ft firtiw to i >w i< (tot itoU pn4atl* ft tow ftaftMft* InUat 4 >>n| fcini to (to nrw Iw4i< to to* rr-- tto mwfttftito | to*4 to tto Uni It to . 4 toftfwC ttot U4m mtfti; ID wufc nmu k4 totostoattoft 4* ton ft tow wrtft ftoiftom rnfi ftifttoft. >yyftill/ ft* ft mill 4 tto toftftl tatoto Into fcy toi ml /.to. IWLM! I m aarOnlarlc IttoiAil k, ftoftfly. 1 tot4 111* to yf--ftt mm itow w Uim tto ##* 4 wft mi M4m ftto * jm bA fiMii. Ndaf. ibit mAt B* aXkl ton. Tkan I* a ,mM anU * IkM altaattoa la toy Ini Ttow toil wart MtoHwi Inn <UI4m win toi toi arvto toi nrryftftJ#ftatfty iurlift m > h im ftfti *m fWtowfi ivrtftft tto twftwtog wtotot, fpriftft. Mi iMMWt wttli Mriil ftnnriiutl HlWl k, Mrtlgrl Hkinjtlll MMW. IHl mWim. to kick iMMlnUM, toMm, iwtoa ly vHk Ik* r*f>krrta MUkillM la aabaah aa4 Cndan* n^a^f>knl*ito, aal tkaa* aalnab 4 Uni to4 nwntfftto, vrtftftry ftfnft|i|* Im rtf Hr^ la Nfkl an at a frula rto ftwtyvt, iii tinifttiiwfttr yfimlawi TUw fhfl* 4m toi ft tomni ton if toi to tto toiy. law Una la Ik, toark. 11 to ,a iu , vac I* >nlto< a caryk,rlaarn tonw Ik, nia|i ! HmU to Ml riftwr* 4 ftwftfvfttft ttot vMftary pnpii|tyiM mr ki*kJf tot, ll ton afwt Ik* ton) M aba, ftwty* tft tkn ftruy 4 II rliilim wft ft* ilwt4 to law ntoM ton* M Uy Mftm. Fiftir# | Mtotn Itol fiinl #* Of town, |k* caaMlan *f |M|alH a*4 la ftftitto to Uni toi narnlnUn mmi toi# Mntln nl tonnal Mrtakatto rat* to toi MV. y#fti#ftt 4 inn to Uk mm* ftmf 4 ctiUir**. Wt nnl44 fm l)m 4*ta ttot mm toft Om rt m tivltol fnn la to, wa rf DDT ul Ik, | i*ill to akMptlaa wt DDT kr tkMna vaa Imto 4*rt vyjft eftllirm ft* ft*lv*y i*f*Uftft toi Ikal DDT to itonl la Ik, fatty Itonn, UAWto, Ik* Wala. ia4 aa kHinal an,UW ,ala Into a IN*ito n tto WTM 4 to*I, 4 H*to D tft- f**,, bwtonUl la ItofMl rfato a, * Unto, vfU r Uto ftfti 4 nUt liftin'Mi *yUi* a* ato* atolli, ik IlUT la Ik, ItoiianM, artf anla tto Iftorani rlinktl Iftrii^nn 4 ftrvtft toi Ift Df'T r^eorir* a*l 4rtk. n ftt kaa* Una, tv* r*ytoUt<*tfcy itrtoft tto niint ftnOii, Ttoy to ya,*ttt, la Ikto Ini totnattoto. F M a##? ft tmylHiy miufftflefy rtfUMUn |* II toaaa'i faltav tint tka nw n,wart anla tto ftftUMm Vy vtot ftmftytotoftattiy k yfw e*l,**l*c la tin aaaia--r Tk*t nn, lkM|k H inti Ttor* ftf ttof ym*it4* fpUft*MMn On# tmk. Ilk, frakakUii, far**, an, i**r*l, ka Mato ftJnmt Mftliy ftftinvftwtiftftUi ymatWltty to tto * tor ka Inaflaal la tortiMl w,l,niii| A MaaAjr fart 4 UtnvUM niatha nyn |nrykyrto jft- fiwm ka, ton *( m af a>iir|llito wt Into m d is c u s s io n MM; MMlIibi m aim* that rruwi it. K, tka fuatftawaiftl ^rww. If wa fu array* paryhyrtnarU M Mft( ft wy aarly tiyi ti rft< poayra la Iwi iy *4 b |b yn>M I wu talking ahaet. Umt toWrfartnra with Ituarparatiaa af ftwlfta arlta aat aUatlar faapwiUa lata tka Qi ui lb KM|Mri>( nntr (<t IftnM Ibn. W m tawltag with m raraphalltb nittotlaa af lb faatrfcj iwmwt lyitm Tb iwyai ay iftwa af Ika Praia k lnk yarttmUrly (pw tka nMtltaftnfMtkft ftabikaft W tka ha-b malarial aa vkkk tka toala Ink k fUmaa. If aaa lalaafana tritk tkaaa lyiliaa kuthrf la nUalkft Hi rakwtiaft. ui rartatoly tka kmagial la wi paptjr> rift ftyataaa to aaa af tkrm, wa an aarlaaity aa> 4u(<Hft( tka Ufa af aa aatoml aa a yaUaat. aa. Bumaooa wtLUfttta: I* ftohlwaaa wa baa* a raraat af am raaaa af <kiM laaf paW palaaa bf poaailfy tkaa aay atkar naamlip, aaraft k fnf taaftlylaaf aa far rapartaf alara wa break IkJa war to 1B9I. Oaa baatrat lantytoa af tkaai kata fkf. I HHf aay ftacaailaa an yaaWrtijrk Kpm ant win pat k aS tola a mf lav awawato. Tka New Yaab Oty Ubatiag inalnwiat aa Inf patot waa tka Ini It baa ban faUawat to flam 4 lOiaato. bat aba wa laafa aara ap. wa faaat ** naUil faflaw H Vara aaa M waa ibaff glrartat at ptoaaa wbaaa rkiltraa aaa rbaw. Wa aaifif U tifrraartly. la aaa Umax at ra0tog fraw arkkb tka patot la paaltog Wat faUtof to tba Saar, tka palat la 111 bat. t taS It tka atftWllto laam A rbOt plrbaf ap tka fUkaa af patot, ata thaaft. araa Mk ak-v aaf wai aaat la Dr. Braflay'a rliftlc. Balk arkaela, IfaryUaf aaf Jakaa liapUw, ara barf at wart wttk aa aa tkto prvUraa to Balllwaaa. Thlt baa kfta wa baaa poataf aa ihtt far kuDtaa halltaitoa ant tka family la aotUf amt tola a beuatoc prnjart barauaa It Jaat laat ftftfa far that cfcUf to (a bark aaf kaap rkawtog aa tkla. aa a labattoff aaytag that yaa aiaat aat pat H wkafa a cbOt ran thaw U aailf aat war tkla altaatlaa. A rbUt rant rbaw aff tka anQtog. Ha tkawa at wbat bat tka Saar aa aa wtotow aUU aaaaHy. f aa aara yaa baaa raa tola tkla arrar la Stp naab. I ramllir tka Nrw Yarb altaatlaa wbaaa rhllt af taw Slat to IM1 af laaf patot piliaalag Ska waa lakaw to tva filfirrat Sartora aaf waa tiagaaaat aa ft atraa tafarttoa aaf aa am 1 aaa tka dark rwaatog aat aa m, aat thaw aba waa taka* to faar tiffafrml boapttoli aat tkara waa aa tlagaaab mata. At taatk tka ftartkal atamlaar tadtat It waa bat patot piliaalag frwa rating patot Sabaa. atatsxAJf wmtiunr: Tba aaxt pgpar. "EDTA Tbarapjr la Faraepa with Excaaalra Lan4 Abasrpltoa from tatoatrial bfonm* tf Dr. laa II. MUIar, Kattorlag Laboratory, UalraraKy of riarlaaatl CoOtgt at MrdiclM, Cladaaati, Qblk OTA THE*ATT IN RERSOM WITH EXCCSSIVI UAO ABSORPTION FROM INDUSTRIAL CXROSOKI y III H. MUH, MJL rumln M absorption by person* |i Industry held (a IM1. many faaclaatlnf coeMbutkes* C may occur u imH of o m or man at th* hat* bom mod* la therapeutic*. Notable amaaf tali. *inf: Inadequacies or failure* of oxisUar thea* haa been th* latrwductloo aad war of EOTA awwauroe for coctrol of processes to which M frthybaediamlartatraacotk * Id, Tlysn 1) aad at M compounds art wad; poor personal kjt- Ha aalta, aS of which ora "chelatiny" drag*. tUaa; Individual or froup anloiiim or In- Chelatloo b th* torn- applied to th* proem* fifimct; wm(iM ooonoo of hod ash whereby a riar-tika otrwctai* is formed la which ptrnirr; oof accidental exposure to readily ab- a special typo of boodlat (coordlaato) taka* Mttxd load compounds. ouch oo Utra-ethyl Ind. place betwees ooene of th* atoms that farm th* Bocssoo Uiooo circumstance* still occur with rlny.i A multirobot pooltlr* toe aach aa bad or mrprtalar frequency, physklau who or* rwspoa- raidDm. wrhea Incorporated la a risf ccenptea rfbl* for lh health of persoets nnnd la oe> or chelata. ao barer retolae Its loak prepartiaa. npatloru la which thor* l* ospooor* to bod. ood A seqtwetrrinf lint b a compound that iwwrta tboa* who sodrrtok* to tract prom suspected with multivalent pooltlr* boa aad retain* these of holier bod poiaoniar. moat h* acquainted la aa aaioalsed state la a waUmolubb product. with a hook body of Information that moot la- EOTA aad Its moaa aad dlsodlum aalta. thrrw- rindt: (1) familiarity with the p>pt<out<bcr, feew. or* both chcUtlar aad aequeeteriny areata. & j physical Radiars, clinical laboratory ftadiar* aad Ih* aatorol ctiakal cooro* of th* ayadremo; Whan calcium la added, a chelate b formed; therefore, odothaaril cakiuio-dlaodlam (Flfur* til kaewbdr* of th* nay* of th* cunnatratlon Z) b the cakiem chciaU of th* dlsodlum soil of bad la tbo blood aad aria* of ptrace* aha ef th* add. odathaadbEDTA.* * rj..- hoc* had Bo mutual npooorr to bad. aad th* HralAcaac* of drriationa from thoo* value* whoa Hurts colony obtaiatd by rtUabb oaolytk mrthodo performed Th* administration of EOTA or Ha am a* by napdnt, pulIM prrsooaol; <I) moral* tkm of th* fort that orrtata Aodinr* each a* a dlaodlam aalta la th* aaltnal orraalom lueoMa la th* chaUtiow and eiimiaatiow of calcium. Bo yinrfcol bad 11ao, oa Increase la th* aumbers caua of.thJs awchanlsia. lt is act dlScatl to of "stippled" *rylhrocytso or elevated bveb of pcoduc* toik manlfeetalbna with them eyenta* bad la th* bbod or aria* or* Dot, by throw line, dlayamtk of bod iatoakatloa (41 a pranks) To avoid th* possibility of prodadaf a otat* of hypocalcemia. edathamQ calclamdieodlum b -J aaderstaadlor of th* pharmacology of potential, ty aorfol tbenpeutk ayento, th* ladkatba* for used. Th* admlabUetioa of this compound, la lira of th* add or Ha am or dlsodlum salt*, their as*, their liEllatlm, pooolbk haratfol do** abt promt th* removal of bad from th* rtferto aad misuse. Item* 1, Z aad A hare beta body fluids, and Indirectly th* soft tlosues. since dloroeoed thorourh!/ ebewhrre.1 * It proceeds t* rsplar* th* caldem la th* ring Mac* th* peirlow* Lmd Ityrim* Coofirewca. became* of th* tmt*r stability of  v ' - kKrh v *2W%SK'V'," f-' IffnftifCitnaWiiVS^, "A:' ';, rnttrSutaj-^Si.*,o^atJ. - <>w-ac,r.m ff, W MILLER EDTA complex. Tto newly formed bad oompie* b highly soluble In water Sine* the bad In tto chat*la la bound (Irmly and la no bogar U an br.ltad (tala. It doa not aaart It* ehaructarlatlc toxic effect*. It I* appareol at Ifcl* point that the** properties of adathumll calclum-dl*<*11 on swat mm of Ik* specification* tor a aaltabla or Ideal therapeutic agent of tki* type; for example, tk* and product ahm. d b* water aolubia; It akould ba atabl* and not radUy broken down bjr metabolic or otkar mesa* within tka bod/; It akould ba excreted rapid!/; It akould, for tk* aak* of coovaelaacu, k* affurti** whan administered orally, and ba radii/ abaorkad; and Anally, It t'jonld bo ralaUvriy txmtoaic nrkaa adminlatemd la affactlaa amount* orar prolongad parloda of tint*. Tk* latter Include* tka effect* tkat might ba isducod b/ tka daplotka of trac* metal* tkat art oucaesary for tka functioning of aotyme system* aad otkar bio lock BMchanlaaM witkla tka complex aaiaaal organism. It kaa baaa damoostntod tkat odathamU calriam dlaodlaa la quickly aad wid*(/ diaparad tkrow/kout tka aoft Uaaoaa aad fluids aftar latraeaooo* or lalramuarular admlalelrstlco. aad tkat It la not coacontratad significantly la an/ organ.' Tka compound do** not appear to aotar tk* ecOutar compoaant* of tk* blood, aad tk* laaaf la tk* apinal fluid la far bolowr tkat fouad la tk* plasma* Aftar parataral admlalatratloa of tk* dn>(, uxmrtiea occur* rapid!/, primarily ria tk* kidney*. It waa found tkat oaar tO'i waa aliaalaatad from tk* bod/ witkla tb* ftrat boor, wbila *9% waa rvmovad witkla ***** tour*. Tk* ahaorptloo of tk* drur from tk* ali mentary tract I* d*la/*d aad nlaUvriy peer. Evldsor* of mal damage kaa baaa obaaaaad la kumana and dagaaarsUv* change* In tk* tobulao of tk* Udoa/a Kara baaa pcodacad la animal* wbao raUtlrai/ large doom war* adaalaiatarad arrar prolonged parloda of Urn*.*-** Tk* primary "debuding" artioa la apparently aceompliahad by rttnorln* tk* laud from tka plaama and otkar bod/ fluid*. Shortly aftor Um Imrarraou* admlalatratloa of a do**, Ik* Iraala *f lead la tk* blood may ri**" Witkout produc* lay ad<ar># affect*. Tk* bad laral tka* fall*, aa escratlou of tk* complex proceed*. Subeeqouotly, tk* bad control of tk* blood may Inc rare ap preciably, and It may attain vary nearly to It* original high bvat, aa tka bad la tka akobdoo tenda to com* Into equilibrium with tk* body fluid* aad Indlrartly with tk* aoft tlaaoa* of tk* body, following upon Um adminlatn'loa of Um chelating agent, tk* rat* of bad oacratloa b Inrrwuad (rally, rachlny a p*k anon, aad (ku sparing off somewhat a* tk* adntinietralbm of tk* rkrbtlnff *ff*ol la continued. Tk* racommaodad maximum do** for admlnbtratioo Intravanoualy for oacb 10 pound* (44 kg I of body waifht 1* 0.17 gn par hour, 043 pm par day, or 1.67 gm per weak.* Tk* druff akould ba riven, la a concentration aot to oxcard J',, In normal aalln* or In a fi% doxtroa* solution. Tk* maximum doa* par coura* of traotawot La 74 gw for auch 10 pound* (44 try) of body wsight. Couram should b* separated by aa Interval of a*van day*, aad It 1* InadriaaU* to axrerd two course*, until or unkuu analytical raulu damcmatrato a ebar need for further therapy. Sorb need exist* wbua tk* coeruntruUaa of bad la the blood fail* to diminish satisfac torily, or falls to remain wad below a daayafou* cooralntion. AO persona undergoing therapy should b* checked frequently for aridamca of ran*] damago. EDTA and fk* frapk/Uali of Load Mao!toff** Tka routine, frequent or lafrequent, us* *f edatkamll calriuat-disodlum, or otkar preamt *r future drug*. aa prophylaxis against tk* oboarp tioo of asraoadr* quastitle* off bad tOBauf to condoned. A* ba* alsraya bom true la tk* poet. Prophylaxis cua to achlered aafaty only by oak* trolling Um aourcsu of oxpoaur* to bod by tk* application of proper mao earn* of ladootrtol hy gbn*. Tto attitude tkat tkla cannot bo act am pUsked (cawrelt/ la -ladaotrial operatic** re, Sect* cither Ignorance of tto true facta or aa on-. wUUngnsa* to curiact oneafn roadltlrm* (Ttom arc exception* which reeult from Um brevity of certain operations or tk* occurrence of uauanal or uafuraeeao cvmditloaa.) la tk* nrcaskmal rirtuawtaar* urkara this La aot practicable, strict adherence to recognised aad properly supervised personal protertivu manaurea to cvo)*ocUon with provision for sdequsl* osaitnry tacilitbo, laststone* upon good personal hygiene aad sound medical supervision of tto workers, win pre vent Um devvinpmmt of cnao* of land latoadcm tioo. Quite spurt from Ik* fundamental pkdooopky tkat prophylaxis should to attained fay rootrW of tk* oovirosuomt, tkor* ar* otkor valid rannone for art employing adatkamil rakiaaa-dl-. sodium aa a prevent!* aMoaoru. flrot, tto toxicoiogic prtaollab of tk* drug ar* art fully understood. Tk* toxic effort* utoarrad la kumana aad animal* from rvlsllwly short period* rt admlaiatratbo kavu beau m*U<m*4; kowoaar, tto effects that may to produced hy tto admlaiatiallou of oven bw dues* ovet prolonged parind* to human* ar* art known aad ar* matters for conjarturs. flemod. alnc* this drug b akunrbad poorly from tto gastmlnteetlnal tract. It b uailkrly that tto additional quaalltis* of bud that may ba eliminated by Its Use would he suOrlawt (A t; Ific ' c u t a imjiAPv is iMH imr M la prevent ISmu when tompamd with tb# tuUl amount* of load that *r ebeocted and retained durlny eepoour* to potentially Kourdova rendi tion*. Third, tb* admmlet ration of tho drof may m'ub tba aymptomatolofy of mild or tarty trad lnloxlenlloa, thereby preventIn* thr iwmynltloa of Kourdova expoeur* before a anorv atrlova or prolooyed IRnoaa la prodwred. rearth. while aodtr tbr tffarta of thr drwy aod for rartaUr pertoda of tin* thereafter, tbo level* of le*d concentration la thr Mood aod aria* ora weenInfUn* and may Ko mleleodlny for dt*ynoe*ir and modlmUcal porpme* riaaDy. tb* no* of aacK aimla teyardb** of iMr aArory, teod* to Ml Umo v pernon* reepoek-dM* far IK health of lb* worker* Into a fxlae mv of aorarlty which. Invariably. la onwmpaaied by a reUutio# of mmM prwredam and roatnd maaaaraa. Sorb artlea, aooatr or lalor. It band to hat* atrloaa cooeeqnenco* for aO concerned. tfitoal Calcium rfh*dine* and load htedcetiu Tto eb)rti*a of therapy la all ratal af bad latoafeatioa art to traat the atato tpltadt aad to aaalat tba individual to return to kb optbaam total af toolLb la tba abortoat lima faaaibb. Paramo**! to boU abbrtlvaa b tbo Immediate tormlaatioa of axpomr* to toad. Whb odatbaaaD raidam dleodlom. It to onto pcrnlM* for abort period* of Uow to tffart aaftiy tbo atualaauoo af appmlabty yreotec peanUti** af toad tbaa btrtiofora.u u While tbto to blyhiy dmlrxMn. tbo aaltat to which tbto module* tbo attimato ciinical coai-M of tbr dtototo caaaot hr ttotod wftb iwUirly. Dramatic eobfecUe* laiprotoawot abort!/ aftar tb* laotitottoa of treatment bat btaa roportrd la cam of potoaola* frtoa laoryuic lead. la otbtr com. bowrtar, tympImu bat* prratotod aad bata a*r***Hat*d tba mptoymeot af additional Haw prtrtd onatarat aocb aa tbr administration af calcium ylorooal* intravenously for tKair rtlltf. Otbtr ftrorahlt response*. tarb at a tharp Awrtut la tbt number* af ``ttipptod' erythrocyte* la tbt blood or la tbo toactatraltoa of coproporphyria la tba brio*, bata bate itportrd frwjototly." Soow af tbo rtolma of awbiertlve Imprtttotiol la mild cam bata btoa ottr oathattoatto la all prob ability, tloro It to haew* that tbto omen qtllt fretjoeolly anon aflrr withdrawal of tba patitat from tbt exposure. Il bu Ktta noted by o number of oburttra that, feOevrlny a rowraa of treat ment, tbt toad la tbt nrlaa ret ere* to total* af lb* w m tenoral order of (n*(nllu4* u th.'v* fovnd prior to Irwliwtnt, Tbit to ant torprttlni alnro It bu b**a show*. la carefully condor!d tony term otptrlOHwlt. that Ibtrt to a deftnll# rtlatlnotblp brtwtra lb* tenfth of tb* rep*** r* aad tba ptrind af tin* orar wblrb larrwattd atnouaU of toad win to nrrttod la tba aria* after tb* expueur# bu c****d-u KdtthunU rekium-dieodlum bu btto ottd fa patient* with tetraethyl toad inloaicntiao.1* *r At la tb* cam of IcbalriUot produced by laoryanlr toad, tb* edmlnlrtretloo of tto drwf rttuHtd la a dednlt* Inert*# la tba oscrotlaa af toad la tto aria*. No definite elynlfWanr* oaU to aUactod to trmnatoat period* of clinical lotprottmtol that occurred In auociatloa with tto larrtotrd ttlmlnalloa of toad, alaco period* af bnpmtmrot and oxarerbotloo* art charactertotk of that Mae**. It to of aeto* baporteaca, bottitr, to aot* that no ontoward effect* of tbo application of tbto tbrrapy bat* torn oheervod. la cwnctotloo II lot/ to ttotod that adatbamO ralrlam-dltodlvm to a 4m rnpablt of forwtliut a chemically Inert Imd-cotoptos that to rapidly eliminated from tto tody. At proaeot, it to toiletwd tto dray to matt ewfd la treatment af tb* trot# ph**t of tb* fllnue. It to tiboty, bowoetr. that it* priorIpal rtrto* liee la it* ability to expedite olialnatioa of potentially toxic oaaatilto* of load from tb* body. By tbto mean*. on* may hope to obortoa tb* period of disability or oamptoymoot of tto iodootrtol worVnuut Tto tody of barreled** mar*relay* Ha oerfol application la com of Intoxication free* bod and other awtato to yrworiay *t*odHy, and it U toped tbnt It* tow* nbt is toad pdeeo-' toy tbrrapy will **< I & A Bmto Laml A1 toto*M Obmao* t4 4< IHL p IM. I. ftmyatooeil Immd t Mpirtal Nrdtoto Uw i h*Ar W* i |to TV IM A t A Issn A tVWBoai tnwM 4 CVM hMMI to to* t-total af tdto I i mull i. M M 4 toto f to* fjmrn**, tol. A AA ftomtoj a* IJkMA. IM M {Mm tie l A A to 4A A' > Vtom m Am </pt to-o lf2 H III. IM v ii rMBM. m *--h. aad a Tw pt MfMe<mMli:>dHto Ato to 0 JM ( tom Ml IMA, IM A m twmaib *4 f | ftotow- idato4 W OA tllctof ly>i.AMInM.toAto AM to NtoM Nlto A La4 (A Ik* IV*4 M M 1144. A a fuMO, t haaMI k A f, C. IdtHHIAI r*M v * to4 MDtotol fitoim TW*ff J Am 4 >M l*d, dto4 II to A Ibmu. A I fcp**at A IrmliM **4 V. g. fa> *W* (Vm Am. .>< < vM tto 4 MM toaiu Td>M<wto to Tmtodto *4 NndMtomto tob >i *4 | (# al 4*M*f Ac# A*A 4. >4 |M MI. MM II hdUM. to fe toatoatoto **4 H >** at Mi IMl faba a Idi to.to to top ItowpaHtoM UM Ktai .< M to.d M*| M l*. IM II IV kr**a, A (<*, f AMidi M | t, Mlitoi Mco.emmi ed tato `lutobm to HaamM W tto *>M ClA I**w A b. >edmnia IrtmuotoU An 0 max t i 1 *Mk IM4 M A L to a ay pad II I Cud i T on a ca| ml Itafyull *tol NktoM all lAitotol (a***h* lnii 4 44 4mA t*4 tort 4 (WM *4 II #A IAAA m s mit u Hit Vmm, n ft fttM ft ft. ft Win, I Q*WW m4 ft ft M' IW rf * . *. 1Wm ti> < . mt ta U *> .* jAMJk. II K A t< 4 Cw-iu. ti ft Ni m, ft *4 lllk M*M B-speMs i id af |<n<lw m I I Al*i4*4 t--* AwnU4 tM TWf lH > fa Ifa IfatrMH **4 tW*.. m * i4 y /w h k #M >a r 0 '*1. iwt ti l t ImtuM, t (*A -e-4 ft A Imp * T >mi W Oum Im4 MMk>*fa* *e*h |4mWI *--m-4*' id.ass 4 41.4 <* /<4 Mm 4 <t l(M IIM ** It. ft. ft ft-**, ft * Mil N MH I, rw t ma *4 # TiftwftH U4 ft in ! tut. liM 44m. Ml, rRAUMtx WKitTUrr: W* win cantina* w dlnrunnbw of TUTA IH-rapy. The --it paper fa by Ur llupo I* Rmllh, of lb* Department of WlilriiA Tbe Children** II*--pitnl. Clarlautl. Ohio. an '1.--I Fotmlif ia ChUdraa ud IU Therapy wtU HUTA." UAO POttONINO IN CHUDtfN ANO ITS TKMATT WITH OTA r HUOO DUNLAP SMITH, SAD. Since bad polenalnp w k m children fa connegeeaci of the prndaction ud dlatrifatlM far mu el certain chemical pfodartn. Ifantinltjr it aheeild be entirely pfwentobi*. Xevert hefaea. the Uhm ceatinaea te tf with detr-UUiil reeaha. ta Cincinnati. Perimc the Ant 10 mat he af IMA. SO inetaacen of tmaln tbwqtla ef |nd by cilidne were Awameated. with fear Onthe reported. Ta tatrodoce Ufa topic and ta haw the fabalastiap taneegeeocw of the Upontiea of lad, we thafl rotate the ntocy ef eae ef ear recent pet I into. Kfaiae <1 had afwftye appeared to be a pretty bufa plrt. with a far yettow bow ta her hair and a fa# life before her, nnttl nety la X|tiwler. at ape two and a half, ahe t*cu to nail, aad be came gait* trtbaryk. After aae day ef theee aymptera* her alarmed panala teak her to the tai rpecicy leaa of tbe Cincianeti Ceaeral Ht-pItaL The phyalral eaaaiaatioa demoewi rated that CUlae waa dronay aad aiarhedly pale. Her llrer and apteea were each aliyhUy ealarpad. A care fal aeuroloph eaaaUnatica revealed only gweetian able lacreaae la her redletaa. Seneltired by the knowtedpe of the hlph incidence ef ptambieia amoap rhlldrra la Cincinnati dariap the precedlap awntha, aa alert reeldeat phyeirlaa prereeded te obtain a Wood count aad emear. a nrtanlynfa, and a-raya of the child** abdomen and wrfat*. While awaltlap the reeaha of theee atudfaa. he gweatloeied Mr*. C. about Euloe'e era! heMU and abtalaed the hletery that ever eiaca Elaine had learned te walk the previou* fall, ehe had been rhewtap aa fata ef plaetor pelted tram a broken area ef the kitchen wall. Ahheaph Mre C had net thoupbt UU behavior U be harmful ahe bed tried goIt* vipoma*!/, but frellleeely, te arreet the habit Wbea the reeaha ef the kboratary atedlea InPleated a moderately revere anemia with keenpbllk etipplinp ef the red ceil*, the y ran rare of albumin, eepar aad coprupocph) ria fa the ariae, deaae Haea af radfa apacity at the eade ef the bmp beet ef the forearm. aad farpe amoaata af radte epagae ratotaaraa ia the Intent!aa] tract, a pfeaomppleo diapanaia ef Wad pel--lap waa made aad the child wan admitted to the pediatric ward ehertly after midalpM. la ardor farther to evaluate the peantbtUty of trad encephalopathy a eplnal punctate Waa per formed aad the rerebrvapliial Aaid wa feaad to be aader mildly lacreneed prearere agaal to SAA mm af water, bat ta raaula ae cell*. Therapy wa* bents Immecllnlit/. fa nan were tivee to remote an mark lendcontolalap amtorial aa pan- aible (ran the InlaetiMh sad therapy with cat item KDTA wa* rtarted by thorn tatraoeamu infmloa It waa 1*0 am. when the weary tatora taaatded late beat rlrtaoaaty eats abort hfa ah la aboetiap the raeapee ef pediatric lard pottoslap. Ala*, be did not oleep bmp. for at 0:11 am. be wne noClIVed that Elnine'e breathlap had be came nlew and IrrepeW. with fragrant parted* ef if--a A check ehenad that her papifa were new dilated aad nareartie* aad s repeat lumbar poartara revealed that the epinrl Said preneera had rteea rrecipitcuely to A04 ns af water, it waa ebvfaae new that aeveta encephalopathy waa prearat rnOowtnp a harried rearaltoUea wtu aeeraasrpee**, It wa* decided that the only hep* cf aartnp the pirfe Ilf* reeled apoa Immediate re lief of the cerebral hypertonelo* Fact eeperfaar# had riwen that the aee ef kypeefoal* piecono cf aw re** eolation** hmipkt only traaafaat Im prove--ert followed hr farther Inrraa** la the beat a >wenIn*, aad that effort* to fetteea the preneera by meen* of rapeatod aptnal peartera* were fail laad--raale aad fraapht with eerie** rink of redden ball Aecardlnply, with the hap* *t Akfa * |*a me* Is4 top mM M ft> I ~ Hir^^yr <:'A * * k> #*&toW-j'--; *iv!^'~lt'^iiu*iHiii !- EDTA TllK*m WtTM CtitUrtEN 57 at <mll coretwul tissu* anoxia consequent |i th* *s>c*ph*lp*tkr, Ik* (illfi Umper*lurorecuUtlnc c*t* >u psralyd by phsrmaco\afU method* and b*r body t*wiiwr*tur* luserrd to (0`f, Tbt**ft*. b* on* hurrtod U> lb* afarHod pawn *hr* a radical dorocupteuloe at b*r train arm* amylid>H by lb* naonl at al most ail of h*e skutt. *topt a narrow *trlp at boa* dosra lb* c*o*r mtlyix tb* aarittal tigoa Prior to tb* ayttallM, lb* (klldi Irwlb lac bad bsrct* *o infrequent that artificial respiration bad b**a required thrmsfhoBt tba speralioa and afuroard* aba waa placed la a Drink** r*rtrain*, la addition to tb* proetowa therapy with V*ra*M aad hypothermia. aotl- choUiwrrk dru*a aad a alow raatric drip at skimmed milk wm Initialed to prevent tb* de- volopoaont of a aocaM 'Caahlaf'a IWr." aad a ncutait bdld watch wa* tapaL Ksrenrtho- Io m, foor boon foOewiac tb* >oarlal<*i at ssrItry aad only V> boora aft** tb* child's arrival at tb* hospital, tb* bsart laal tsa**d aad ah* waa d*ciard d*ad- Tb* raaoha of tb* analytical rtodbw for bad ato wcardad la Tabb L Tam* L <m Tb k x Asilvm **a Laaa t e itcft *t*t*4 ----. M4 t^t. rvm Cw HI tmtam >4 M rV TMto . UJWmIVIMUmmI War* tbl* aa isuisted a* aawswai cas* history or aarratlr* ml*bt stop bsce. but f*VT*ttaUy tbl* U atID aa all too typical pktara. Sow* two o**ka fadooiac Uala*`a death. eor cilairiaa* aad pstSoio*tst* reviewed bar cas*. W* abooU Ilk* to report aeon* at tb* taadadoaa toeoybt sot la tbrir dlatusolm. A* already menllnasd. bod poboaiap aaaoay chltdroa retain* a aariooa meonr*. lta rsportad iarldaac* la aay krab rrtlsrt* primarily tb* to lar**! aad a-sariaxss of pbyairiaaa aad tb* rrsdy araiUUIIty at analytical rtudb* for bad. A* an must ratios of IkU fart, tba graph incur* 11 depicts tb* InrtdMK* of p*di*lrtc pisaablam to Cincinnati, where w* aro ladud frttqaal* to bar* avalIshi* lb* faclUtba at tb* Xrtlerlnf Laboratory. It may ba aot*d that dariai tb* yssrs |t| tbrcb Ibid oaly *lcbt raawt wor* dlaynoasd. I* IMP tb* larMsor* rose, bot w* o*r* art yrt aUrtsd I* tb* disss**, for tb rs* of tbrs* f(|ii rases bad bsa wn* rowsly thought to U prtksaysima, aad It n* oaly apoa postmortet examination that tb* corrart dlacnoala oa* mod*. Tbit sipsrime* Jarred as rloisally and, at caa b* h m, wa aooa found that tba dissaa* waa pall* prorabat. Further rvldsoc* of tba larldsac* at thla disras* mu thrust apnn ua thla part aawuaar by th* discovery of *rtd*nr* of abeorptloa ad toxic amount* of bad aa a rolnridmtal finding In too chlMreo with ether major disorder*. la each laslanc* Seen* oo* rilntca] finding tcianiBOB to both plumUstn and to tba other dla*aa* bd to th* obtatnlny of blood for aaalyala fa* lta toad content. lirodby and hi* codesrues bar* similarly ahowa that many anr*rofnl*ad case* of bad absorptioa to potmtially toxic amount* exist la certain segment* of tb* population. They obtalasd blood spsrimon* freca U1 children to dink* la tb* oclooronomlraO/ deprived aorttewa of Baltlmor* aad to 44.4% there waa *etd*aco of daacerooa absocptkm of land. Tba tup of Clarlaaati (near* t) abow* that a relatively small area of tba city ceatriboted abnort aO of tb# case* at bad paUoatac brtoesa IM4 aad IMT. Tb* Involved arsu are tb* Isos meat sections. Furthermore, aa urban rxdsvaiop meet baa forced tb* destruction at old baton la oo* area, tb* more lucent cooes bae* com frat a region which, art too many ysara ago, footorad th* taw hundred. No a*w paint baa b*a ndd*4 to then* hot**; torttd. tb* mplanaUea far tba appear*ac* of saturalst la tb* fact that tba paint baa been allowed to crumb)* aad pert; that loan wed Informed familto* BOW Ur* Ia tba area, aad that oorloocooocuk rowdition* fraqasatly pceesol aoaad child tearing. Tbaa, rraa thowgh modem baaaabidd paint* may ba ataatiaKF teas ponoBiae imi-io m rx emmd swantaa ta caomasn aoaam flpel t lap* W*4 f >! > I WM ( m OwfaldM Cu ^m i Hw#ml it* O--ttMiil Hm> f*d INMHi .; , '.w, / siV : J ' f. h surrn A # W 0"--1 O*'-' MiA'wf Ao IiiiIh W Imi *r a **1! `**A M |lln| M4 ........... mo m4 iJ. Of m* h A* U.*** h IW fcw WM. (Ha In Ah ha* wA<< W A* mw <m*M n w ** ! Iwa a * wf'** 1* A* AfH wM at A* A|. InMn*. tit* Uml of dtHAted M polncolnp will rimaln a public boaith problem Uf *aay yuan to <***. Kefor* tureiap to therapy. w wtob to Mr*** a In of tin dialed difference* Mm child hood *a4 adult phtmbtoaa. Tha typical tmdlap* ta adalta of peripheral anritia, abdominal colte. aad toad baa atoar tin fan* are aB daito rara la children. AMcmtlnnl pala don occur urlth a*Uwtl frecjoeoey. tort K la MO ae mw a* to nut (ha child to double up or to h**u a beard-like abdomen. AaaocUlad with tin pala ara tatocminmt romltlnp. aaormia and cuoatipatic*. Tha major concern of pediatrician* to tin hlph toodeor# of rntt^ulofatk;, which aerate la aboat m third of all childhood toad potooalag. la Uw mnimpemesl of any child found to ham atoorM potentially tocic amount* of toad, two problem* and ba farad rrpardton* of tin peonn* or abaenro of alpn* of actaal latonlrntlm: tha Immediate tumoral of a* much toad from tin ooft ttooaoa aa ponlbto, aad tb* pnoewtloa if mtpanra to toad. For tb* foraar probtoaa, caVtam diondluia Ct>TA or Varna* to tin arCaptad drop of choir*, tort therapy with It I* far from Ideal. N wmerou* atodle* bar* abowa that tin laltlal coum of CUT A pt*e* latraTowowafj riami cmly a email par coat of tha total tody toad aad hot amt alt tb* toad la tin ooft tlaiun. 0a tb* ttiitii. only it mim of toad to ttoored bp tit* drot twrw aad four or Ar* dar>` lint* to required for thti. Arcordlnpty, la laoat lartatwa* wo (It * at toaat two tour*** of therapy aad *t tlmn laaap ator* ar* needed bofor* aafo Imh of toad la Uta blood amt Oral Unrapy for childroa warn uswto* with rare rareplloaa. for act only U Vrraaa* by thto root* ton effect!re la remorlnp toad from tin body, but atoo It to frecruaoUy difficult to ba eartala (hat tin child** npoaure to bad h*a rodad. A furthrr problem wa hart mat to tb* raarerba- tloa of cacrhral ijoptaaa la tha drat 24 to 44 boor* fo5owln( tb* taltlatioa of pareotanl Unrapy with KOTA. To data, a chant* to tha oobrwUneou* at i*trw*c*Ur rout* of adotlototratloa with *fforta to limit tin oolatao of Bald (it** hat Ml reunited la a clear-cut Im provemant la aar remit*. V* art bow rare-- aeeodinp a more produal octart of therapy, to- ptaaiav with U mpaa of EDTA par kp of body welpbt oear tha Int 24 boon aad than. If al tm wait, locraaalap to T1 atpm par kp pap 24 boor* for four aaora day*. It ohould b* rtmaad that Vacno* la wot a ruratlv* drop, hat oaran owly to lower tha amount* of bod la tha body aaora rapidly tbaa error* by aatural protean**. Therefor*. Vara*in atom* cannot ba MuUanf a* adequate tbarapy. aoperUOy for tb* wnr* Urrataaiap maaifmUtiorn of bad pofnoulap Eftrl* la pecToot fartbor npmr* ta toad an atoo roafrwatad with diAcohln, tb* major of than hriap that tin caean for pba ara hat fally uodomtood. To b* aura la many caooa, poychtatric aboormalitto* la tin child ar dlatarbaarca la hi* mriiurmwot raa ha Mtawttf and bacauaa of than wo routloely orafc tha ' ototaaro of our aortal aarcic* departaaut. Hourrrar. attitude* caaaol b* chanpad CToeaUpbt aad ocunomk dcprlratloa oftas dad** correction. Althoopb a modarataly orerra Iran dodrtmiy awrtnli to abaoot ualrenally found. Unrapy with inn ha* not bora of nark rain la abort!ap tin plea, ana thowph tin an rani a la yrito rad. Accordlnpty. aa la other form* of load potaoatiag, prmtrtir* offorta muat b* band upoa lemotr- top tb* amre* of rapeour*. To thia and. tin labor* of tb* health deportment* hara bam *f conaldorabl* rain once a can of plotabUa haa bam reported However. little ha* bam doan to rorrart danperom rltuallooa before potocmlnp baa occurred, ta aptt* of our kaoertodp* of tb* aptdnukdnpy of tin dtoaaam Wheat tin dlaaoar baa prapraaard to tin #Wrephalofathlr at*pa, a ml threat both to tin brtla and to Ufa ratal*. Tb* marked awrfllop of tb* myelin ttann with!* tb* rlpid bound* of tb* *k*n mutt# la oalreano Ittcrraaao la latra- tincraatal pieooure and la rompraealoa of blood raaaala aupplylnf lb* brain. The lateurlty of tb* brala retta to the* thraatomd by anocla, aa well a* by poaaiUo direct aciiym* polnoolap by tha lend la aa effort to derrann* rerrlrral mrtab- ollam and thereby to minimire any coratral BteUbollc dedcll of oaypea or other aulrtoaU, art EDTA THE*ATT WITH CHILDREN i. bn, brix lb pul It noatb aoad kypo- ahboupfc It leeboro100 tb* removal of load Mop* tbermla. melntainlnr tba patient'* lanporatar* fold, oaly now* a relatively am*]} aaoeat of U tb* vlclalty of ROT to |T. through the tM4 load nponf to tho total la tbo bod/. A* of k* park* u phanoa.'idarlral method* of rordlnr*/, tbo major offort la tbildbood load : pnrolycinp lb# tconpermture-ropulatinp conterm. polooolnp amt roolioo* to bo to pronat Dr*pile therapeutic failure* In ocroral of our Ini pceure. Tb* rooponaJbillt/ for tbl* of?ort aboald tial oV-rmpu eith hypothermia and doeplt* tb* rot primarily arttb eur public health dopart- >; fort that Ihta form of treatmcet do** locrooM r lb Mnplnltf of fluid tbnpir 004 may foUrd t (to monl of loo it. vo b*U*v# tb procedure b Oeflriootly oiraptr and rorrto* adeqaal* tborrtl* 11 t Baa. a a. b mu . w . ruu * a iwua 1 tw loaauo* 1 col noHoi far caulof lapwwf reaaka to joaUfjr further trial. Whan, la ipllo of ether ibnpf, tb* nnbtl a u> vu * Omonlriinu m * Immmi TMi /. Mu 0*1. MOO. >11. moua. out a ' ^ rSTwt1 M>*l told pnowo tootiauoo to riw and eho* I i I >--WI. K. S. C Ml U &. hMt> 0> fupmi nunmno <f oocb pnmrt develop. 00c* oa Irrapalar reeptrationa. ape**. markad M ^ Qifcnn Aim Ctotm Lai I f Oal Md lMdaMMa MnttMfMHb / A Mob M tM IML krbpnifU, popUMraa or prolaared ninno i t. 'k . MMiut, L ft lam m4 ft. ft Unui Ua Mwl hdtM to to* gw Ilf Ml ttototo f Ul Mill i (boo radical nntnl tempwuloi hot bora n km <r rw to o mm a j ix ; gm <w gm "V '..i :a foaortod lout Ufe-oaviap omnn Tb* raoslta I C ft Aw Ml t 1 reported by KrLaerU oad Mcbob (Tabb III gto. ItBUI H.m Ml Ift L ftUito Ml J. ft lap tb* tatrodartioa of Ula Method *f traaUomt, but unfortanaUly oat/ life aad Dot bfala fonrtiaa appear* to bar* bora tpored. Wo baa* fia qaenUy arrod earlier neaTooarrlcal lBlare on Uaa. preferably bofor* major alpha bar* de veloped. Hootwf, tbia procodaro to of nek a draa!it oator* that oa* caa oaaily aadtnUad bow rafoctaat a aaarooorrooo might ba to mode*, tab* It arltb **>1/ minima] iodicatloeia. Tbo tkmpf of acuta *oc*photopatb/ accardlact/ r*> main* unaaliofartory aad again w Boat arp* that pnnalln rotber tbaa tar* b* ear Int Ba* of dofoaan la coorlaaloti H aboald b* otrrooid apala that bod poDoolnf ceaUaaa* to bo raropaltad with dlotortda* frequency la rltla* which ar* alert t* tb* flaax aad equipped to proeida analytical aaalyooo for bad; that tb* court* of tb* bod nowaday* ta paint which waa applied une year* ore aad which ha* been allowed to fall lata de tector*ld out**; that tb* lllneeo primarily laoufna oa* to four yoor-old*. aad otrlke* alnuot oetlrely la tb* omaer month*; and that tb* dlenrdor I* virtually roefined to tb* aorloocoouaol. rati/ deprlred alum area* It obould further ba otreaeed that operiftc therapy haa not Diet ortlb great aacre** atira InWilcatloa, and ooporiaBy aorepbalapath/, hove occurred. KDTA tberopy, outuiAM mniiut: TV dliranlia of Dr. MiDrr'a and Dr. 8a>Hb*i papon m ba opoaad If Dr. Harriot L Hard/. Aoaartata Phyolclaa. DM, Occupational Nodical (llak, Miuatki actta Coneral UooplUl. ML AAftftm Im h a j v t : lUw b 4*r*b mt ck!U bb plaftUtoi tub it ^toUtortm If lb ftmto b mft MMftMtbT t wk lb M if Safttr* M to tb yntliw mt gorgftjrrta iHftftdt-- Dr. Malwf m4 t bn tflw *tolm4 If 4fftto* KfiM ycyfcyrtft to fmk piftairtiw Uw to tb mtn) torn-- i^Im, pmmmiblf fggblitftg mmm mt tb ajrwgtMMUto(7 to b)ta ftweto m Ito4 nb. I mM hkm W --k D. SmHto ft> pm* Um Waft tbt li b byirliM to touMtotof; tmm m ftMcto Um4 ftmm tto soft Itom M gwMttbb twit tb gfaftt--I ntbf to ii--TiTb b*4 fnw ftofttottoft! ImI tol tb b4 tbl U Urmtmn Abp I wmmdwt tf to toil to* *towfi4 ftbtt < nMvtof D f tb lni If Mt wwll rtof tto n^wtn, H wtii to m ttot mi *mm4 w4 fM 4torH fttowt ft ismtor mt wtwi mt ulriw U>TA. W bit Umyftt ttot to tto wft tlm> b*4 U riwml nttto tkb 4n*g m4 tto 4n to iHM tto M flaw ffmft tto Arlrto Into tto nft Uww, m4 ttto rii to ngnlit ifilt ft*4 ifil* wltft tto )4kton lm ftf lto*gg tto totto In. MUbf iM Pt ItoHto tort to* --igtoilftlftf, f fpWbiriVf f* it to4 oft tto urtiMii trtH it M*MAfk*riu Omni mt ft* iilt tot|i tot* to#l witft imt U4 f, ii4 i fftift ft to fcl'TA rmy 4mf fw ft ntob Mtk, H gM to tto pe**t wtor to on i*<r*Oftf ^rvtfntinM tmti mt MitM, tot If no Mb ftto frm tto 4rmg to ft tojr n Im, tto tto bft4 oft* ,umf .t '.;.-:;;;',1.-",:v ; 00 DISCUSSION tntlM *l M */ *l* U Ik* asm* M H w >1 *Sn v Sofa* IKU tVwff TSW >4r<u ISat MW * km/ /will** WA |a1 IS* oofl limuow. Srrriy till I* all Mill anww k*l fayoloriocr; IS* W7 k il*r*4 tS* l**4 aw*/ u *rv*t h (na /rotating sik *0*rU. YM tS* MMTfUtk* of f y*oyo*of II U tl Swart aft*r U>* to*to*i of CUT A tkal Dr. Soil* Sw* Sn Mila* m sS*wS I>r. Syr* IriW m* Sw Sat lHtto o iSm *f *a rSOAf**. It U arrtai*)/ If aw* ft*** a tlacto Am* to a awa with a Asia m*al*4 r/o*wr* to UwA wto I* Koiaf a paaato, as la Dr. Ill**'* t**w, aaA I tor* la* ar tkr*a *iU*r ram*. aaA oa* rti a Imandra* r**U/ ImparUai larrvam la rrtaar/ 1**A iurtto aaA ISla raa ta rorroSoroiwI alts *a ar mar* at/** aaA ysytfa* af 1**4 latoiWaltoa. U*a Ito Atoc***t* of Swmfu) UwA rffrrt I* ataA*. TSW slrtSm m* as torj *a *//nr/rl*u AUenortir aramarrr nrryWf my IntU. If sa/, n*k. Ml mw * la *4wlu to Mjr bwMp. A/fwrmtl/ Df. YaawrA*/ I was llatoalac wltk lalinM to Ito MUtor Un'i ** K. C**M IS* rato at oSkt tS* r*/**t*A manlm ISwl w* a* l*g*r Sara */Mn*to 4n| I* f!*w S* l*F*rUit! Dr. Lamia, wk* Ui 1*4 1U1I rt/ortom* wHS fTwr/a af ***** af l*Aa*t/il WaA t*tolWallow. TVrra I* M lawtia al*al tSI*. Sal w* tor* All ISW 4 rot la Kriat* Aows Kick Sto*4 cwlriam f*4 a (rra/ af Im/arUat rwma ISwl amA to to lmk, Sw* ***fi*l*4 frwa Si* U*k *fal ** aluAwf. I ISiwS toy wrr ! < waA IS*/ an to* /ortmr* iSat ISU Sw* to A* ml IS* rato al dkk rarrmtl/ Al ****** 4 rttwn If WaA to Ml a is* Arm i* |tna,.sa /**s*/* is * s*m tsi* * toy to Ikwl II to a Adformr* to ratarraSiln/ *f wfwtrf Hkiny. TWy an aftoa Im/imlSIr to Alaeaam. TSm I* a amyrrildly to maa/ WaA tSa <*Mnl arrtaw* r**w of IS* SIM aa4 tMt * | * wry mw t S l*tor*to*4 to Dr. StolS a*a tWraaw *f aark **/ rttk rafr*mm atoUSg of lyyatoral*. II w*a* to to a KiKI/ townie**! tot Aiwun, I WralA *o**t to tSto era*/ Ikal am. Dm* to too/ *a atof tS* nlriia CDTA al /** laanlrr Ito am *f CDTA to *4*eto Am* fm tto mam tiarr to rlra af *K*t to taM a* aSaat 4raga**tk /ar/inw. ?. IS* raamfSattoa *f toraSral n*Umil I iStal all iSraa af m ar* *|tw4 Ikwl aral CDTA I waalA lito jam to toratlm Ito fart Ikal Ito coaa|Sib| arm* an nrtslal/ ton to ala/. to **1| to to Mauiail to to naAimaiA. 1*4 I lay aaA Lwtiai f, I tstwk. f*4 mAh far ** waal gm tot* tto ntim. TSal Sw* to* wan Amo. fwlto Ito* mrlwat. Wi Sara (to rr/mto f.lhs CartatolF Ik* tkria af a* am* iSal to totaattoa* Sari. Carrmwa, l*al aaA stSrra. aaA aaw Ikal tot af arato toakttj, CDTA to Stoat; arnfaL an la ISW War* arw rsHf af an, wtotr Itom I tStal N to ta/*rUat to m*alM* awa Ikwl Ik* Win to laSalaltoa af to**/ m**l* af Sack /atom. tala *f ******** am to rrarial to latllit acato Owl, ISW ra/aaatoa af ImwkAir af (Srlatil^ ar*ato otforto. /arUraiartj to ito aAoit. I Ikial tto cSM- I ISiaS to ***/ laa/mtaat. TS* to* Salaw *S*wa a S**4 *rill*a Sw* Sara a* ad gwm ***** Sjr alSara fra a*w rSrlaUa* a**U wkkk I rafWA sal af Ikwl I tototlm H. Sal a) dlakal afntim Ik* Ittmtan: rmkUWjwta* -- ft. B - Alm*th/S. Ik* kaf; Sa* a faataolir *S4My to r/rtoiaa C. DTTA -- Calrtom aah af DWIk/toa*- toMW tow4 If H Wat ynwk4 artik Ito UwA to* Irlam4a*/r*tml* aoA. CDTA -- C/rlSraaaa t, nyUtf. aaA tSto rato al akfcS Ito to*4 to /ra- > trft*Al*atla*t*traa*Or arU. raloA to tto My awl to** a tol to 4* wttk Ito TrainnaadM to* tom trtoA la kaaAlla Hfmaa to rltokal Hat* a*4 ttyntot* tofi mrnllim fm ITUww'* flnam. M. Dr. IflkMi nfKld ywtwky aaA to Ito fra atSytmiwnrlwaWa* ynUntk ariA TSto aaral/ aaif raarn af TS /oifowH>c wkirk I S*trlrf 1*1*0/ la awrlwr totaim 8* Itor* I* a* kantim Sal ttot w* woalA all acr< ISal JaAwtoa* am af CDTA far aval* ***** to t*r*4j IS* Sato trvalawat. mi* ISal Ito nat/l af ria*|)il*f larlato Sa* raackl m aaA win to ***!/A arttt I*. w*rall rwa/rasA* ta tto fatan to US* rara af IS* Aaamrtnr Omt* *f mtoto. CSraaW UtkHy. k/ wSkrk I m*wa tto rvvoll af sa. a. a. swanaa: It W *aa*r*Mar/ Iwaibay aa/aaar* to tow 1***1*. akwva /****>--III* towvl **- tkm* /*/** torn Sma nnnnt I A* fmt, kww* ywvrt *f loaA arrr a toae yt*4 af Urn* wHS . Ikal IS*r atrr* mm* |Sl*c* aMatlamA ikwl IwSmatory rvtAoar* *f Io aA tOrnl /ta* If)****, aSoaiA to ISotoa/Sly ro>yA**W*< /riaH/af)/ Ikat to* ailaalto* ta mf o/talow. Dr. MUtor. rail* fwr Ik* Aa Sara a r*ry mbw /rIJwa of UwA /* 11*aIof ta Jrfltto* am af aKart. stoat/ (tore Harm* af rSUArra *SlrS I* SamA *a mrtwia fwrtara, CaKa CDTA. Wa to** Wn wry mark to*/r**m4 Cinl I* Ito w/* af Ito rSUAraa. aoawlly || to M wltk tto /*r/Syria **A Kontioki* atornmalllto* atawtS*. Smarm ISal I* S*a IS*/ S*cta la walk rriaralaf to a*t*l with amh Inalawal. I faal raaaA aaA /irk a/ tSIara. SmawA, IK*/ mail Karr M SmlUlto* I* IS* wiaAom af **nr*MI*f IkW, a **ruia **rir*a*i. a Sma* atom Ito luiA* /*M Ito rowliM S*4 tow* arm **A arrr acaia. I w**IA tlto to toll SrtoO/ af mttStc w* tor* aaA /alt/ I* *rr SO y**t* aW. m IS*/ raa ektal* Ito UwA from Ito *44 /slat ISat Halm *4T. AaA A- Svwa AMwa That to to am a atoato As m *f rwtolam aal!/, ISW w*r*lly ** la S*l wmlSor, S*a AlistoA CDTA lalrarrM**)/ Ai*c*mItowHy. I ISIwS tht* a**/ ra/UUrim aaA a miiA mIA**W Sflag |Sr *S**rS*A tor* **) amt UwA tork from IS* tort tat* is* S4mA Mrraas W# *S*a*A Itol |S*m wAoll wt*W*f from war Hof* ta 0.-r, for rt*ia/i*. v* sal/ *t*0 *1 Ito C**r*l ttoo/u*l *w i*W flam a* ******* *f OA *.* af towA /#* 1m** a/ to I *4 ito am# */**/4o m* af b*4 (-***.Ia from for* * Anto/lrmto? TUy at*of la **/y Sol y*tl, af tot yrr III** with a ataaW Am* *f t g** of CDTA rf Ito rSitArm * a* Aoriag IS* yr*r wHS UaA lalr****v*l; TSW I* a MgS tom to work from. / Imilag of* Aoilwg ISo m amalkw r Yitriumnrfr- ; KDTA THERArT WITH CHILDREN . 61 TWa *ri( Important point W (Jut ftf fti#f*#ak, kvoft to Mato*** tlto 1U m* to tto rot 94 %WlrW 1# ratbar #Wa|ft#. A# bkiory w* V*r* Um i i>i ni*w)i/ %* w#** * tkiu b# i# IrrUftUft. b#* l# Lolnf t oat (ftUft- Uf w#lfbt, Ul p*f*1*#*t *o*#tipaUm aaft xumtouf wttk tvo i^rlkntUr n**A or dl*roofrt Waora fUa aptaal floift, total protol*. *rt op vary kt*rWftl; fr**a a**#*tor# araoftft rlfklj to lin ator# #r*aft 400 mg *%, aaft I a## ar* tWat to wa baft)/ Injurrft bf tWk #tprrlra<a. (f poo giro oral Vrrwn# uk Waft la tto Cf trad, jrtx Mt W# b*f Ut mk li Mir cUaW* Uri U rock aymp- a*)/ atoorb tto VfiiH tort ato* .Uoifc a tart W tin crrvr la cbUft af tbla afo frooy la tW# aw** tot rttaa, *<1* K- Tto Varaaaa-toart raftilaattnrt tort Urn# portWuUrly. or *> ftt aa/ Ur tiara. Ital rtn)i rtnrt, aat It la pvaaibia tm Inal Umi rWUftrv* nM W#* if ir ttrfaoa #i#mta*ft for raproymrpbyrla*. | fttft M War Uk natiaaal,- k 4m to tto (Uma, aat (to wt toi Tto, tto lart atoarl | waM Uka to ula to itoat Ut Ka## fwottft M U W moat rrllabt# awf taf Wot ft*4 rla^k ta 6a. All p*o *oft l* ft frtkyrto aartwtia,. Ttora to a Unto wltow that aaalvM toa aaaairttot^ Is 4a vUh totnaala, tto mk a/ art**, ft ftak ft rtkor, Ur** drop* l M*tk ftd4. a*ft #Wat# it TVU k #xamht#ft onftmi ft par^irrto aalH to aatotto, tot peiaaa>ti. Da Mato. I Ihlah H la. toa la.ratalto raUrtta aa4 adar VWi li|il afW 1ft oftaot#* If (k* rkift U* aa aahaali vnh Iaa4 ato aa^aato ttoaa to totraatoM trm al Im4 wiHkr. tb# vtlao *10 ako ft toft- Ml tot attor tolar, raaaalato, raaalaat aa4 I 4**W color. |aW**ily mi coUr k aat rriiUiftt nrttW fattoa a fnal lamaa to tto aaaaat to parfhjrrta * mlof Waft nmaft If poo fit u j i rrliirft nlf rWarv at all, Um rWttft Km Waft |kiwli<. aatoat to toa arlaa to ttoa* aakaala. aa that aaat(k, aa attor ,a>ta haaa attto.4, aat aat/ Tb# ml kajortMl |U( W to Mtklr taarlliti toa aiaittla, la 4a aM Ito at.ar.llaa to hat tmlMftl I>aa*l 4*Uj. OWrtooolp tW rWflft ikmll W namf fnai tW aoorr# of Waft, Wot Uii k aft irtiM M ftfva/i pa*#fbl*. K#*t, mttfr* alWmpW ftkoolft W maft# U rH lk Waft Mt mi (W tiiaorn hat ataa toa aaaar totato a, tto tortal illato to la*4 *1tor H la to tha tort/. aa. a. a. armtaaras: Btoaa. r art taa aatha atoatk at i at HUTA, I aha,14 Uto to cattoa |aa Till ran W Wftt W * nrkf af arllrk T*t*p acatoal raaalltrla, k aa a faaaraa to tto tiaatnat ftva /tor* af* ** *f to ilUl^r Uw rftOft; Wo- to ta*4 art, aala,. I totkm It ataj tort a nal (hat mr. *r* foooft It Ml M <fNW to poll tk Waft aat rtHft; lk It v m to Warn It k. t ifta ottb alt tto lWr*p#otk artitm wa tlrarft. Wot t vaalft UU to imlnhi tWat tokkfip Ik eftfara k ** kp^toM tkaa tto mropbatlUa. tart ftar I got to tto fiat vkrr I fftt (tot ft ft i f pro* ifia fttoaU to tor Niflft (too* <W0> 4i m w ftooft a tWf ftnoil tto ftllfWkk ilfw aft vMvfktopU;. TlSi /#r I ka rktH a; al*4 la tto traataaaat to act* alawtl-- to ch04nau I ttMI Ba to aaartlaa |ra araiaat tu aaa to a4alta alar, any nwa 4a4attrtf #a^iaaa4 aa latortrial ka4 .alaaala, |rl trail trUhaat thr m to KDTA, art alart attart tto aar to aaa 44altlr. traafrat. Aa traa a. tlraH/ atom If Xrto. aa taaaa yrarr ait, hr rwaarla, ttoa* fia fta mt to tto hrt laalrmaint aat traatto, (to talk ar naala, ttoaa faafla (at tottar. lotarabal toco*r a# ka Waft f*oft larnr* (Ui tto immrftial# u*o f (vfUto ftA^nUift Mvftto aotb a Itktolto ra (i m for crl. to far iWk Tto taar to CDTA *n arm mrtirata Ita4 fah aaa I a,. Aa a aaattrr to (art. Dr. Martaaa a ft( (aara a(a to St. Lmla fatotrt art that am to tha poor *r tor# o#rft tWt* biti*JIx ftaft km act faaaft ftiuwpfroto nrrMoftry. Tto kata point k to ft* Hart, to Laa Aarrlaa hat ataatot Ha ahtltaa arkh CDTA tart.a4 to toaarvratto, a aaatral ft* ft* or tto fttWrf t ar# ftaft M waif for ktfaxift prr--urx ftaft raoToktao*. to. a ft. h i m: L#aft potaeoinf la rWUftrvo fttUf to* rraaa far tto r.4arUart to ataaaafhrrlr Irrala to hat to tto aa.lr.art.al to aafr torrU. I thlab tto tofartort (ratl.M la. aa Dm Harty aat lUaaShort rrr la tto inter. W* Waft #o# UH Jmm--rf ac w *W ftwft vf Waft racrptolitk, ffttoinf rWkto* aaaptoakarrt Iwtrfh;, tto am to tlarnaal*. If. arr art t4*ralto( tto hmtr atkara, raaHaatl pax, okWW, aft room#, ftoooaT rf#aft to M| ft tto ft/wf tmiarriA If# rtorVft to miK aft to i m MMnrim TkU a a* m>rwily rartoft to rWkW#a pax #arrpWa)Kla. to*A#ft for Waft to*w# H war January. Iixuai r#, H to* topp#a. W to#* tto torn# m*m*i I pMl la tootoa, it* rortotka Hi tto Mar moatto. Wot tliH ttora arx nut at atbar Una of tto yaar, Ttora a*t| to ottor factor# ttoft toftt ftf aanlifbt ft# rkamia aart hat.Hrt tototaa. Wa at* art (rtttoc to tto |mrral frartltl.arra aar Ito tortaatrtal (hjrrlrlaaa Mm mat thru* aart Ural aaaaa. I traalrt imirt that arfaaluttoaa art aa thla am. aalrrrrtOaa. tortartrial aartlral fraafa ar airtl ral aarirtla* rotaUtah faaala to .ttalltrrt ph(alrlato to tto amaattoatol rtlaratm. aa that tutarr ar tomr atom ra* roaaolt artt* ttoa* fh/ikiaaa far artrkr aa to 4la(mala aart trrataaoai. D Ikt prorlpKat# Waft pokoaiaf la iwn# rWitftraa aft In *iWr parkfta. W K*ft ft toft aarlftrat attW ora] Vanoa# vtoa H m* HfH irnAcf Oof ptaclkra * to tak# tto rWUftrni t. jri |ft Wor vita# aaaipk to awtolaMiat# tto Waft p- oalaft, rWaft art tto <t| lr*cl *rtft fir# ttora now oral Y*row I; ala iak# oa# tkllft fw| of*) Y*r***a aa tto Wr*t ftay In tto Wo#pU*I Tto rWUft fftl rmaoto* ft# Waft aat cNttnuH ttHAtrunr: Tto noat paiprri "Tmtram Arpirt aa aa Hapanmmlai laratoi(attoa to ract<m hkh InSurarr Ito Rraponaart to llumaa Rut>|arta I. rinrtr DlrlM Uxl Cm. |oah<U In tto Atirw|ihr," t>r l>r. Ralrtt A. Krho*. IMrortof, Krtlrrlnf tolo.fatorjr. L'alrar- to** a#rtoral/ IU tofar*. Wot Wk Waft itrMlw all/ to Clnrian*ll Callrir f Madkla*. . >......... v. ** - .: f- v '- tdjaiittataton^^ ' ,:s ! PROORESS REPORT ON AN EXPERIMENTAL INVESTIGATION OR FACTORS WHICH INFLUENCE THE RESPONSES OF HUMAN SURJKTI TO FINELY DIVIDED LEAD COMPOUNDS IN THE ATMOSPHOCf by ROMIT A KtHOR, MLB. Ikm mti w rf u aaeatUferinry Utl* for mjr rootrlbattoo to tbla pntna baraaoe I lldat know bow to gin I better o m. Prrbepe yea Bay com* to tb ceertuaiaa tbot It woold bar* bM brttar bad we gone oo with tho diorooolea of tbo oab>act that wo war* dealing with Jeat prior to tbio Uaa I waat la explain my porpno. howwr. nad caB yoor attention to o m or two thing* which I Ibtah an af IwdunoiUI iaporUnre. Wo ohaS adcrotaad tbo problem of bad poiaoalay batter wboa wo (Bdrntud tbo mataboliea of load la tbo baBaa offa Iwa aad orboa wo baow aioro aboat tbo phy*lology of tbio aBtoriaL of tblo Biaoral olroewt. It may bo of nano latoroat U reregalM that wo peobatdr baow Bon at tbo f ruiat ttaoo la tbo Md of tbo aloml mrtaUJlem abort load tbaa wo do aboat aay other element. I oao a obabler of boado. TbU la only boraoao tboro an aooao aow ekeaeota wbirb, barapao af tboir Ocwaaaa. ban booa loebod at with cvauiderable Intraolty. Pot wttb Iwport to tbo older ilianli, tboao that wo ban booa roare raid orlth for tbo long pal -- tboao which. Uraaao of oar famfllarIty with them. or tend to tblnk of aa being wofl oaderotood -- I tblah t caa aay wttb munable oafoty that wo probably baow am aboat tbio la roiatioa to load tbaa wo da la roaaortloa wttb aay atWnatal la aay ran, I wtab to rrrooat to yoo, la a nry abort oporo of timo. what wo ban booa oadortaking to do enr a period that begaa la IMS aad to atlO noliwbf: to fertber ehaddeto tbo BetaboUea of load la tbo baBaa orrialBO After tbla, If Uaao permit*. 1 obaB wtob to re fer to acme practical ceaelderatieaa that rtdsto to dUinoeie aad to ladoetrial kygtoaa. Onr tbio period of timo la tbo Ketteotag laboratory, wo ban booa devoting aanaino to a baeic otody of tbio problaoa. It botraa wttb aa attempt to oloridato tbo ocramace aad tbo dtotrtbotioa af load la aotorr aad la biologic amteriak. Tbla baa Dot baoa by aay Baaao toaplrtod. bat tbo oaawitlal caatribotieoe wbirb wo ban Blade to tbla Md won pobtlabed la tboir Initial form la IMS. Then. a few yean later, on began to atody tbo irtohollna of load la boama oobjecte oador coadltloaa of both aorawl aad abaormal Intake following tbo oral adadalotn- tloa af load, oadortaklag to dotcradao prrrtaaty whet bapioaod oador tbo roalltiini of prolonged, toatlaoed admlnlatration at variable Ionia of doaaga. Tbo maolta af tbaao lonofIgafInao ban aad an booa paUlahed. bat to tbo orient that tboy bon boon paMtabod. tboy appaarod onr a ported . af aaoorol yoan. ending abeat mo or otgbt yeere ago. Than aboat olgbt yean age. era be gan to atody tbo other important variant af. tbio problem, from tbo point of vtow af tadno try. anmrly -- what bappoao to load wbirb la la tbo rnpirvd air; bow aad to what oatowt It la reeplred aad ratalard la tbo pvtaxmary apparatoa, wbat beppm to tbo rate* of abaerptlca. rvtoatkm, oimtiaa oador tboao coadRleon. ^rj *- I -.* ' 'j1 - &?* . '*'* u **.<* 'V'lU&S- 4^ 1*8 -;.- ;r r -.-*.'- -..- -. t ,* V ab^fc^wiffa^aStdia'TKMndBttoMmi i^o'aiTiktk-a-aana^m^ . RESPONSES Of Ilf MAN SUBJECTS <1 ThU Mt no* beta bliM. Aftoe h w dtlil trltablp ranoa aoaM of tho bad to bo dopotlltd paaro of *wt la thU M4 tot haca ccmpbtad opoo llo lotvao. Tbt dlolrlbutton opatora at aow tlx axpaHmaato oa foar wlijKU, two of tho bottom lo tht tooane of nenoeal. Tht ma wbkh httt bom duplkated. Wt art ablt to rt* terial |noatt through an etarUooUUr precip port oor prorrtM, oaf mp raaaoa for reporting itator ta tha ootolda wbtrt It fora Into oat UiU rarhnllp la that It U, I think. unaatltfarlorp of tho mol a otarko of tho Uboratorp, aad tha to pubtioh thlo malarial la titlaa htrt and tbrra, oiparlmrnt U. therefore, contained wlthla tha la MU aad pbraa. 8orb reporting folk to ad- anlt arta of tho rhambor llaolf. itaipUti oar porpooo, la that, oa wt hart aoaa Tho oqulpmmt bratod outoldo tho chaabtr ktrr today la tht qwatioao that hart bora robed, oa a obotf b tho maono. la a epoeiftc experiment, tho pertlncet farla aboot which r art la deaM muo( bo pneoalad foil/ and aptUmolkaSp. of tatrodariag tho bad rompoaad lata tht * la abort, aortal briaf paMIratioat fall to pro chamber at a kaowa mt tho problem la all of Ita fartta la ooch a rata and wonttrrtka af that oot raa fraap Ha fall ilialtcaaca ThU room fa oqeipped Therefore. w* hart withhold pabikatb*. aad aa aa efBea. Oat cannot thla la tho third rertml report that 1 hart audt act aa experimental eob- to lataroatad greapo aa to ttat ot hart It rood >ot la thlo kind of tx- opto tho permat tiaa. prrlmcat wlthawt |ki>| I would Ilka U dloroet tho Urkgtoaada of him onawtklap ta da thla tort farthar, bat I tap aap that Ita pat- other thao twiddling hb tor? ohjectlra la to andrra*aad tht problot lad thumbo far Pro dap* a all of Ita nmUkatieao aa far aa tot caa aator week. aorta aad a half tho coolrolM cowdJlbne of lahtrotory abaoroa haara a dap ortr a par- tkae aa kaaaaa aabjoct*. If a aoora aptdhc th- iod of montho, watko at jerlice rrart la tiad la tht rroop of oaparitoata poora. that art aadtr trap at tho ptottat tiaaa. It la Tha motkadolorp Iht Ido af apprablag tht tUt arta of rr- from hart aa b that af epirmtoc? tapotaro ta toad la tanoo af nek having tha ladlridaat UUagt aa Iht ataadarda that wa art naroraod who b Um tapedmtotal rrlth la Iht M af actapaliao; tht ataadarda tafaiart cohort prtritt m which rtdala to tha oxpoaara ta Itad aa tho part daphroU tomidm af af tht caaaaaaltp la fvtiofal. with reaper* to rrarpthlap he oato aad hat la aafa to tht hackgroaad of tar kata- drtaka la the ntm af ledge af tht atnaal awtoballom of Itad; af tho a dap. ta cohort >| adat aaaroldahb txpntort to bod. plot what a hart raidod. ta ctdbct ad barwed la additloa from iadaetrial txpttWaro. forte paaotd la the bftaaloi with Heart 1. wt hart a raopira- iw m af thlo period of torp rhajabtr, tht ootoldt of rkkk b Ubetrated. lima aad ta maiataia Kaoratlallp thU U a chamber audt bp tht thlo rtflmoa dally aoa of ttaadard atrial partilloot that art avail- throaphout the parted abb at tht prmot tint eo tht Baitd. plot tht of tho ohaarreUoaa, la- latrodactloa Into It of tht mmniy emtibtoey rladlnp a period af act and other equipment that told prodact a boo thaa ala aeatht dynamic rtprrimmt bp which t raa Iatrodart prtttdlas hb latnodwc- lato Utt atmoaphtrt af tht rhaaabtr a known tkw lato the chamber, coartotratloa of a knowa rompoaad af bad la a la order to ootabUoh the known ttclt of au Wirt*km. la wkkk aa expert- pettrra aad Iht rharnr- montal Oabject carrbe oal hit dap1! work on tar of hb bad mHob- A Art dapt of rack aark for aorta hoan aad I half a dap. Tkta pmrrdart olmaUtoa Iht nodiIlona of ladwotrp, bat act Ihnot af nmmrally aa|arv to bod la tht atawphoto figure 2 mrrrtp obowo mo m of tht drtallo: tht lalakt of air. tho roorat of dUUibullaa of tho otrtam Into tho rho it bar. tht woo af a faa baton and at tba and of tha lotwnl taka ta die- I mlpht pelat oot la pot at thlo polal that wklb It U norraoarp to totablbh tho laitlal mrtabotk palltra of thlo ladlrtdtM. thlo pro erdurr ka* oomrthln* Bmrt. Tht pattrra of tho bad mrtol*4Um It on chart; ootaUlohtd la lanao af prraanl dap rommaoltp lift that wt raa carp taollp ibtort not oalp whdhtr a oubjort U aor- alpata tht air throughout tht nan Inoload of aul I* kb twkortor, bat abo whrthtr or act he oalaf a taarhoakal dlatrlbotot whkh would la- U a rrllabb *ab)art. If ho drdotoo work from M KEHOE the norma] patten It require# UveeUyatioa. Flyura S ahowa an x-ray diffraction pattrra which la thle lotltnce danwottrataa tha natur* of tha compound need. Since our tart/ and tra ditional experience In thlt area of had ta tha atmoapbere hat reialed Wad oxide, we hart rhoaan, for hlttoric.il meeone and alto for tha aata of deny it, to ota Wad eenquioxide which W produced by tha cotsbuttloo of a email quantity of tetraethyl load la a atraam of propane throoyh a Bunteo burner. By thlt meant, yoa ran rryulate tha alia of tha particle mod tha cos* centralloo of material tnlerinf la tanaa of tha tpead at which tha tetraethyl Wad la fad to tha propaaa atraam. Thlt proeidea a rotwplettly reproducible jya am for peoduelny Wad of a kaowa ataa of par ticle, of a kaowa chemical character, and at kaowa and my ataady rate of prodacttoo. Flyura 4 ahowa tha electros alrrwn|il( pic ture of the Wad cocapound weed la tha chantLae, U thlt particular laataaco. la aa expeeimeot In which Wad eenquioxide of tha arena alee la A mimo. (Individual parUdeo la amal auaAeca art aa larva ae .17 micron.) Flysre t ahowa tha dittribatioo af tha partWit alien, and you may aaa that thaeu la aa ereo dll. trlbutloa of the parlWWi la tha chamber. Flyura IDuatrataa a troubleooaaa peeredera and ona I may any that la euK troublnnme. Thlt mathod ahowa la not ustlraiy aatiefarteay. Wa are put ta iha aecruelty. la detenulolay how, morh lead thle Individual takee la and retalne under theae cooditlaoa, af belay able to deter mine the Wad la the aiplrad air, and wo bavo detrUed a elmple method of M>| thle. It eaobleo the individual wklW bnathlay air coatamiaated with Wad. to expire threw(h aa eiertraetatW precipitator Into a Douytne bay. The expired air puttee throoyh the precipitator Ant at the uhortcut pooulbto route, rather than throoyh the Douylaa buy. tty thle meene we hare been enabled ta determine approximately, at WaM. the extrot of the pulmonary retention of lead, and you wilt recoyalur that cut tha Wale af the calculation of the teed nocentratloa la the air end kaow'.ay the reap!relory volume and rate, we are able to determine what portHm ef (ho Wod breathed la la the coureo of thle eerea and a half hoar ported wet actually retained and ab asebed, and wo are able to determine, aa I will aherw you later, aomethlay of what Ha fata hue Wea, At I Indicated, we Kara done elx experiment*, > e-f which tootIsued for Are yeura and two ruootha The eerond oeve coatlaued for four yeara and four month*; the third one few two yuan and til nweilht; tha fourth em for Iwa yeara and te-vea neeithe; the Afth, for two yearn, and tha one which It at pretest la proyrene ha* aour yuete aa for a year aad a half and erlfl not be ooaaptrted far another two yuan. ftpew I Theae are troeblemme expertmoate to carry eat, coetly la terrnt of the time aad effect ef il Upum A c V ! 3 - i i KKSJOSSES OK HUMAN SUBJECT* as the people lanM, pad ISqr (U b* JutlM only mi the but* that the queetloea that bar* bran railed bar* tbla moraine and tbrourh yeeterday about tha ndditlM of the behnvitr of trad tindar a iri>tf of conditions ran be anewered aatiafartorlljr la d o other way tbao by thle method. Slora lima erltl not permit wto p Into tha individual experiments, let me conclude with there few rnmarha. There have amerfud from there expertmanta tbaa far. In accordance with tha variatilaa of doaafe aad panicle alxa, Ihree major facta. One of thaaa U tha diacovncy of what happena whan tha raapirator)r eapoaare ta dlacoatlnnooa Tha Individual ran rhea a plateau, with rwepect to bin rata of urinary earretIon and tha con centration of lead la hie blood, when be ta oxpared for Bee dajv a wrek rather than erven. If we five land by mouth every day, or erven day* of each week, tha concentration la tha urine and tha accumuUtion la tha body pom op at a fteady, oaeeotiaQy cwnataat rata throufhout tha whaia period of uzpoer% for aa loaf an tve r*nru- la thaaa raperlmanta tha aobject readme a plateau la from alx ta atfht nwntha, at which time tha haifbt of tha plateau la Indicative of the revertly of the rowdillaaa of tha expenure. Tha east point, and tha ana which 1 niah to amphaaiaa at thi* than. W that whan wa Chance the aiM nf particle two thlaca vault. The parileWe of auO aiaa (OS nlcna) are retained in tha iunf to the extant of about BS'v to 40%. With a Uryer partIfla of aboat one micron we note a elifhtiy creator pulmo nary retention, around 40%, 4S%, ep to M%. A very cornideruble proportion of the perticiee of 3 mkrone b atruined out la tha upper ranplrntary tract and appear* in the face*. At thle point the Ir 4 of tha facal content la differen tialed aharply from that due ta tha food and. at the came time, the total rata of lead abeerpttun, in proportlna to the lead roelent nf tha air, daermaan. 1 think yea will andenUad why ! sold. at tha atari, that it would be difficult ta prmaat ta yea much la tha way of aa account nf what haa beea dona and Warned by there axpirimiaU. I have believed It to be worthwhile, howecar, to brief you a procure report ladkatiaf that tbla week la ruetJaaier. and that We art carefully nialalnc atrp-wire the factor* that taflaapro inhaloUoa. aa well aa there which influewce ubaorption uud excretion nodar the condltiana of tabclatloo mx . uAtsrm aoupcrai: Oar Chairmaa, Dr. . Wheatley, baa beta obllfvd to Warn. Ha had to. be at a awrtiaf la Waahieftea later today. It la quite ebvioua that wa art folaf to ron- tlare here after lunch, aad If Dr. Lauar doaaal mind, t am folaf to aak him to poatpona hW die- ewaaioa of Dr. Kahoa`* paper aatil w* mret afnia r after hmch. . - - v-x^-Air.^ 1 * j FRIDAY LUNCHEON SESSION 7Ntvtmbw , I9SI f. i: A SUMMATION Of THi CONFERENCf FROCEEOINOS p THOMAS L SHIPMAN. AO. a tana* m*. rw Knrtrrcu: Th# h m tloo win be flreo bgr our old end pood friend. Tow Ulpnu, IlMhk Dlrteloi Laodor'cf lho In* AUmoe SrbotiAc Laboralocp. Los Alamo*. Now Krttn. BA. TOU* L MtlPMAM'. Thb l>U rtoflp boon CM of th* mo m atimsbtlap aad onjopabb asset Up that anp of oa, I thlak. Ion itlnM TWl Mt few tadusUie* tint tn u wad? wf wiStap la air aad discos* their proAIrsn* m IM bod ladostrp. I m can that 0*0*7 OB* of oa fade Ikal (A* Association b to be cnapraUiUXad ud thanked for prvridiap thb epporwaltp apla to consider tie* problem* of bod. AM Mr. Wormor, 1 hop* that TOO will transmit pjr f**Uap oa thb to tho othor oOton of tho Association. *1 r. L woaatfX: ! wta U ptad to. Thoak fm. n . sNtnraw: Of miH H poo* wfthoot **p h that thb tafia* ha* a aparkpiad. and wo know who that aparkpia# h. Tho caopbtotr tlewha aomtp of Maafnd Bowdttrh b pnfeahtp tho thiaf Which b larrHp Wopoaaibb for tho pat aacwaa of thb ooftap, aad aamia t al|W mention hla subtle approach to thoa* who art reported to apeak. atartiap hark rartp la tho wlator. I would abo Ilk* to oapraM jaat a word of thaaka aad appreciation to tho aiaaarcwwwt af th* Drake Hotel. which ha* wad* os aO a* comfsrtabb whlb w* haw hooa kora. I haw learned a lot la |h* hat two ftp, aad It b talaahb knowled**. Oo* thiaf that thb artakw haa *w>pha*l*d wbo7 b that la thb who** wattor af ladoatrial beafth w* ar* dwell** with two akin*. medicia* aad tauriaaortaf. I da at* thlak that althrr an* b war* Important thaa th* whor. bat c m the othor hand I would tap thb: Th* darter bp himself raa do a pmIp (of hh. Th* raptaeor hp hlaurtf tea do a protIp food >oh. Hot Help hp worklnp toprthar aad approclatlap aach other** respimslbllllr aad potat of clew raa thep da IK# reel af rwaMed Job that Ih otlpeocba demand. New la those af pe# with bap *smarts*. thaee word* map have a fecalllec rtap Thep wens afehea ea thb aaaa* recasts* tea pan apo hp Dr. laitaa at Ih* epewle* af hb aotaouirp af th* aveetisp. Te th* two akin*, medal** aad anplaeerlap whWk Dr. Lo o m meatbaed. I think w* Waal add a third. A* w*a so tdnleac thb wornlap. th* Add of raatorvh U a boor Wc member of th* bam. Todap. I feat wo aaoat ntopba It aa ruck, rotopali* It cheerfuDp, aad realla* that raaratvh haa much ta offer, that bit bp bit It b alowtp onbrklap th* prob lem* of the phpakiopp of lend which hare boan pan]lap wan for ewr tho part two thonatad pear*. . Th* ladlrldoal who b chosen ta eowwartw a mrrtlap of thb aort b la a rather aaeavUhb position. A* a taatter of fart. If there U aap00* hero who would Ilk* to taka ooor thb )ck. 1 woold (Udlp rhaape place* orith him. Th* pom tkn arise* aa to whp Maafnd aabetad M. 1 dual thlak that 1 hare aaoa a caa* of bad pebonlap alar* 1 waa la medical school. W* rertalalp hare aa bad Intoxication at Do* Ala mos. ahhowph conaldarabb amount* af bad ar* Uaed la a rmrbtp of wapa/aad than b aa * trowel? aasrpetlc laddatrbl hppieoe propram to coatnl It Perhaps, howowc, harlnp aa aw to pried aad cemiap at th* prahlmt* from a robUralp aabiased poiat of rbw. 1 caa carrp owl a mmatarp which map puB a f*w looao threads top*th*r. 1 weald Ilk* to mention each of th* touad down presentations that haw been made; bwt I raa eoip trp to toorh oa them la proop*. Th* a*massriter b la a dilemma to know whether he should touch co oalp a few mala pelata which haw ariaeg dariap th* meettap. ar whether be should, piece bp piece, po erer aad attempt to touch oa everp poiat A second dilemma rtbta la that the aoauaariwr caa anlp brtap eel those poiat* which aw of ialeroot to him peroonaDp, aad 1 am oure that abacwl aap *4 poo Would rir# th* tuaunarp la a wrp different wap. W* started off pooterdap moralap with Dr. tWfkaap'* paper, aad Immediate!? me paM# ba. portoat poiat orwrptd. Thb was broupbt out aot ml; bp Dr. tlelkaap, but abo bp Mr. r*Ub*, Dr. lUullsf aad Dr. Keboa, all of whom stressed the dancer of ostabllsklap a dbpaoab af (IsaUta purolp oa tho basb of bbuntorp tost*. Aa tadleldwal with pt"bim la a abb per so* Th* dlarauab meat be established bp the aewnea af the phpslclaa oo the basb of klstorp aad phpsWal eaaatlnatlcm. aad with th* roaArmattoa of bUwatorp tssla af a wide artetp. SUMMATION OF THE CONFERENCE *7 > U ccnaldeetag tha earioo* paper* which h*v* bean given la th* put two dap*. It It rsthar rulatlnp la the blood, but the amount of land whlcfc la tlxad la bon* where we coot pat at It: Interne! ini to go bark to th* procud In g* of tb* It men* to m* that it I* a* Important to kaow t inerting too ton are and find that most pi tha paper* given today and yeeltnUp hair* covatar- what I* left behind a* it i* to know what ha* been excreted. parta in paper* riven tan year* *fo Dr. Bat* Wt renlip don't know occur*lei/ what tha knap'* paper had two counterpart*, tha paper* bodp krd -- tha total burden of lead to * hr Isttaha* and bp Stlaoc. caae of ptumblam at *np depra* poo thoou to Mr. Frank'* papa* on "Health Control la mewl't o -- la. tha Ceramic Induvlrp" had a counterpart la Aa w* war* comlap arer here ia the plana the paper gteao tan pear* an bp Sherman Pluto. the dap before peeterdap. Dr. Foreman pointed Mr. Fraok'a paper expreoaed. from tha poiat of out to aw a phraae la * paper bp Lockl* and tie* of tha aafrlp aoplaeer. and Dr. Ftnto'a Tompoett from tha sorteWg Jeurwal of M*4i- froca that of tha phpakiao, the oacaaattp of pooi- tint, January IHA which I woold Uk* to nod: lap tha vsrteoa akin* -- tha phpairiaa'*. tha "la aap proop of people expoeed to tha haaardo aafatp anplaaar'a and tha laduatrial hppi*nlat<* of land obaorptiao a limited number of can* -- la a control program la lodaatriaa o*lop land. of frank poixnlnp wltl revolt. In the remainder, Dr. Srhrank broopht eat mo point* worth however, aipaa of toxkitp win aa* appear, the retain!Ill ring. la hi* paper h* broopht op tha aheirton hariap aoccuafaCp Immohiliwd tha fart that tha aamber* md for milrnm allow, major part of tha abeorhed land. abia ceacaalraticna. of aaraultp moat b* oaad aa There ia pood evidence to aupput that aup paid**, that th-p aro a rampruml**, repreetnt- farm* of acuta atrea*- -- nod ham b* refer* lap tha pooled kaowtodgt of a proop of expect*. to wort of Auk FairhaS, Minot. EwntTinlT. Thap rapraeaot a compruml** la another wap, Brows -- "caa bring about reieuie of thl* ah Ha too. I thlak aO of oa will apraa that tha oaip tal lead sad pie* rlu to ijaptoM of Mad Ideal do** of aap tonic malarial U wra Eatab- llohlap a anlaim allowable roncootratloa, I thlak thl* I* aomethlag which we ahould therefore, moat b* a coraptoeala* between aato heap ia mind, la tha caa* which Dr. Kino and aa abriovatp toalc doe*. Thl* I* rlaarlp trw* pot*ad peeterdap. sad which ha* bean referred la the 0040 of radiation, the field erlth which 1 to hr Harriet Hardy and other*. the Happenr aa tha ateat familiar. W* woold Ilka to ha to aac* of cirrulatiap bad. the reieou of clfculai- aero doom to radiation aa w* would Uha to Up lend, 1* a matter f laiaawaC have taro dura to Wad throophnot Industry. Thl* meetlnp. of more*, would oat have head On* other point abonld b* kept ia mind. Man* complete without John Foolpor. A* I ml II atan- lion wat mad* of tha ectaalonal lowering of lop to him pcoterdap, aa imap* cam* bafora am. maximum aOowmhl* concentration* or permla It waa at tha Uow of the Apaaleh lopoUHltm ribi* do* in. Is MOW cauo It la perfertip tra* and John waa coo of the Jodpea, and I Joat that a lowarlap of a maximum ailo-wxbie coo- tboophl how 1 woold hat* to h* tha poor heretic cantratieo rapreaanta new knowledre. that tha that waa broorM U front of him. (Laophtor) amteria] I* la truth more toxic thaa H was Tha atalnarnt* vhick b* mad*. I think aro thoopht to be. la mm c**aa. hoeever, a lower- locoolautabta. II* U opptwad to ale and la favor lap of thl* *oct map reded onlp aa Improvement of virtoa. but be haa plvan u* aocn* wrp goad ia nr m termlootpp and oor abllltp to pro definition* of what ala and virtoa or*. tect people, permlltiap trt to approach more 1 win juet point out on* thlnp that ha laid: rkwelp the mo Ideal that ee ahooid etrive for, a cumptUux* with at*lute* do** not provide im* It crrtalAlp I* to bo hoped that the runtrvverep munitp; pood faith la repaired. That. I hop*, of lead palat laald* took* *ow ha* bean ended. wtO be imnambarad. Indeed, tbe diacaaalon* of llervep Elkin* and Tea pear* ago than waa a paper plea* bp Dr. Herb Atoklaper an thl* aubjevt were thoroophlp John*. Thl* pe*r wa added feua to It, tad then ranvtnrlnp to aw. and I cert*inly Kara no worrlen waa a very afmllar paper t>p Had Jubnatreve. Tan ! '. about drlnklnp wler that tam* out of a tank pear* ago Dr. latia prdnted to lh* fart that palatad an tha In*Id* with land pnlnL Dr. John* vtaltad hit patient*, Dr. iohnetone Y I would like to mention on* point that arena brought out the fact that h* vtalta tha**. under- I* mp mind whit# lie! eeltip to Itahraum liyer*. aland* than, talk* to them. AO *4 pou her*. 1 Our mathoda for aaalpilnp Ur<d. urine and air am aura, ar* awarw of the language* that art** fu land ar* conatanllp improelnp. althouph thup 1* difir rent Indualrlao and of tha Inability of atlD leave aomathlnp to be deelred. On* thlnp tha nverapa phyalclan to know wt>*l thaa* paupl* kick we hae* not pet baa* abia to do la to are talklnp nie-ut, to pet any kind of a vtaual atndy, rw* the amount of land wkkh la beinp pkiun of what their nvupatioo rwaQp nawlata auralad. sot lh* amount of land which ia cir- of. ) OS SHIFMAN Mjr Introduction to Industrial medlrina gend I caa visualIts her next headache of trying to * Ot*nj jnn sr< came (run a dear oU pel'*'** reproduce this whole thing with Immature. grow whom a frw of you may remember. Dr. Frank ing mica, not adult mica HrhuUnphl, et the General HUrtric la Lynn. Dr. Now, K I)TA eras tut mentioned lea yesra flrhubmehl told me once bow he rvalustxd a ago It didn't exist. RAt. was the new thing, doctor In Industry. He would tieit e plant nod but in his pnper on HAL Dr. F-sgte said: "I Have the doctor take him around through the wish to suggest that although HAL has peered shops. And If, universally, live workmen turned so effort Ire to the treatment of certain typea of from (Mr Job. and sold. "ML Doc." he felt heavy metal poUoainr. there la no reason to be- tint that doctor oae probably all fight. An in tiers that other compound* may not be developed timacy between industrial pfcyelrtaa and work which are rvsn more effective aad which, acting man le the rear fee aan for (he eatabllahnat oa the name principle as DAI, nuy acres to of the conAdeoro which obviously meet nUt abstract lead from Its combtoathm with tissue*." An for Ted Wstecs' paper, he dwelt on wonrlen I feel eery certain that at the next session that have bothered him. I doa*t think them of this meeting- ton yean from now, KDTA will if anyone who le better qualified to consider ksve passed Into limbo, that we urtO have new the W*1 problems having In da with industrial compounds which wtB da the Job very much medicine than Ted, aad certainly if ere lamp together the statements made by John Fwwlree, better than HAL. We wound ap with Bob Kshae's paper, aad It Ted Watera and Arthur Johanna, era hare aoaw eras Impressive. What they are doing at Ketter Iking* to remember. ing is iveiarih to the grand manner. When you la Arthur Johaaoa'a paper. I particularly atop to consider the deltara. the man hour* and remember hla statement about the three criteria the boredom I Laughter] that ban gun* lata for acceptance of liability la cnmpeaaatioa mesa. this -- 1 don't vast! to ait to an* ef those chasa- First, the eotaUUhmeat of a true and positive bera for even aad a half hour* a day seem If diagnosis. Second, the establishment of an artoal you give am a desk aad a radio! ILaughtor J'Out causative factor fur the dleea*e in qassllua- this U realty tha fuadagmatol approach. Thla Flnatly, the rsiatence of tear disability. I only I* asiag mss. gattlng him to what most nearly wish that aD of the members of ai Industrial approximates a toxic working environment aad ncridrot board* uodrfrinod this as err9 at Mr. studying him. It Is a tremendous chore, and 1 Johnson. believe that Bob aad hie associstee at Kettering Ten yean ago there were two arena which are to be not only conmtalaied tort encouraged ' really preeeated aoanthing new, somethiar to keep H up. which probably would hot have bem roneidrred I am sure that I da net have the Inst treed had there hern a meeting before that, la IKtf, hero, because all those who still wish la talk Ow of theee era* the study of edahiltly and will have ample opportunity this afternoon to particle site, aa area which was not strictly get quest Urns or answers off their cheats. Wa new to aoaw toesutigaton, bat I think It was have had. as I said, a splendid overt tag. aad H rather new to much of the group at that meet is with great pleasure that 1 now tarn H bach ing. The second new topic eras the use of BAL to Mr. Bowrditch. to the treatment of plural ism. Again this year we had two things that wee* new. W* had Anas B*et>er`i work oa the efforts of temperature, humidity and seasons, and the rn*!iK*M nowtirrrn- Wa win reconvene at two papers oa the use of KDTA to tresI ment. too minutes of two, starting off with Dr. Laser's Ar m Itaetjer'e paper, to my opinion, was out- di-rue*ion of !>r. Kehoe's paper, fur which standing. It has been a difficult Job, aad I there wasn't time this morning, aad We caa thsa feel that the work which Arms prevent.d this resitlnue with whatever ef the various subject* morning le to be regarded aa only a preliminary of the past two days naycm* desires to disease report. Obviously much remains to be done, aad farther. - *3t ( "1 /r*' FRIDAY AFTERNOON SESSION Ntvtmbw 7,IMS Rk mIh of Oft. KfHOf? f*p*e BOUNO TABU DISCUSSION & cnaiiMaN naxren) nowtuTra: W# *18 prwread with Dr. Laorr'a dlaewaaloo of fr. Kehoa'a I*p*r. M. j o k m urn: I w m certainty lapnarrd with th* trrmendou* magnitude e( the riacwjib atudy udHUln by Dr. ICfbn tad U> group. Eight )mn >ia I bad 4h flwan aad frirtWg* of briar w>| thorn who participated ia the atari of tbla atudy. la the put amra yon, I bar* bad littW or M opportunity la fiibw Ita pamdiip. It mai that a *orb aa ntrwin arid ln|1<at, ddtiar lata tbr metabolic rrlatlooahlpa of Ind, coaid hardly br dm Justice In Imty miautm. Up tba tiaar Dr. Katior bad bad tba optortunity ta abrlrb a llttlr of tba bncbgrouad of tbr iqrriant. there na littW tiaw Wft ta permit aa to dl|at *bat war found. rruca tbr charta that wrrr pt bafarr aa tbla morning a few quretiona aroar ia my mind Oar K fottoviar tbr period of tbr tahabttfaa of laarf aargoloaldr. three vaa a riar la tbr Uif Irvad and. concomitantly. la tbr ariaary eacretioa of lead. If 1 Mid correctly frooi tbr rharta. tbr Mention dropped ad ia tbr ariar rather abruptly, wberem tbr content of trad la tbr blood, after dlwuntlauatioo of mpneurt, tapered odf rather gradually If I remember correctly, la poor early *orb la tbr Torot lea aad Thirllee, bee lead *ar gtrew by mouth, after the doaagu perkd ora ever the racrrtloo tapered off orvr a rather Weir aad gradual per iod. Thil did aid aeeea to be I rue la the aubjeeta ahowa here tbla moraine. I woold nt for rotameat on that. Am*her pint that waanT dear to me waa tbr matter of oomr 30`. re 40*> of port Idea wblrh err retained I* the rmplratory trod fallowIn* addltheial mpmure I wonder If Ihlo waa reta1 ned, or depnalteu oo tba mplralory mueiauL If It waa depnalted, boo murb of II waa bet la tba muroua and therefore (wallowed later, or e* federated T I think alt of ua are Woking forward In the Anal pubtkallon of this work It la of aurb magnitude that one m*l alt down and artually aludy It before re*we>at4e t tenmeat may be made f now Incite dlwucvhw of Ihle paper. HL a r. uttZMt*: Tbla work of Dr. Kaboe** Ilea la completely with what we mot hncur la order ta ba<nr about ohat or art gulag to an cen|Ji*h. or are nnompllehlag. with Ur are of KDTA. There have been nomrroue rrporta of raaro that errre Ireoled by KDTA rkkk indmated that at the twd of a feiatlrriy abort coorar of treatment. the ariar and blood maipleo bod ret anted doom to what wo rocaWdrr a ton maJ le-erl Ur-continued eipeaie, aa we kaeo la many caaeo of iadoatrtal lewd pdauwlac. alec indicated by Dr. KaWa work. aboww that throe am, If Wft above ta the norma! mrtibnllr and rturetloo pna-eatea. woold tab* agpeoatmatriy twice a* long ta return barb ta tba normal IIm aa they veer* la rettiny ap ta their high Irvul. Someuaa aiae rcmairated ta tba affect that KDTA. la formlar a chelate wlU lewd, waa ad a one-way pnguudUum but followed tbr lavra at chemical balance, la that there la ahrnya a rrvmiUr action and It elmjjy goo* la ooa direct loo ta a point at chemical bnlanc*. If tbla la an then it would be pnualbt*. la riving KDTA la too her* a daae, Ic latriaar tbr actual Iuric amoemta of Ion liable load percent In a critical cam of lea Icily, aurb aa |a a child with mrepbatitla. la my e*perIrene whb rceulta and data la the wee of KDTA I bare bad no ram that baa returned to normal level*. crew after probmyed um of KDTA far part that re quired lor the relief of tymptum*. Although urine leveia would return to ncei-etpueure levulr after air to It wrrha* freedom from um of tbr drug, they atlll tame bach to practically the prrtreatmeot levela until altar throe to all month*' intermittent war of KDTA. Tbla la eaactl/ wbnt one would etpect from Dr. KWi premntatlon. untewa Ihr drug Were rontlaord over a period of time Ibal would be roughly pnt-rt tonal to (bo llmo that tkli pallool war elworhlng hla lend, acted ujem by the factor of the Increnmd evrfrtb-n due to KDTA. ta other word*. If a nlnglr Injection of KDTA raaoed SO fold, 14-bour evirrihai of lead, ww would hate I* any that that fepeeocntad 30 dayr Inalend of on* day of getting rid of the Wad; and. of poor**, aa Ihe KDTA conllnur* la b# given, M V WgMiWWg wiwpaip^^piipwpf A* - * wiW 1 * ti uSK|Ctl3l -* ' ' -- i: vy.'n-. 70 OlSCVSStON tb* amovat of M ncn<<4 falh uatll H rr*fUi ft Irrol oh*r Ih* nx-WtUftblo laod ootaid* of tb* boor* It all oxrrrtrd. Bui ft* aooa M Ijino *ttoa, (brmlcal ruotlibriam brtopc tb* blood back (ip to lb* baUocft -- drirrmlord bj tb* total amount of hod ift tb ftpstrm. ohlcb Hftiu la tb# lorn. Tktnfsn, to ftccwnpluh dalaodlnp. EDTA ftroold bar* to bo a**d *r a period of lira* tolrr aft loop ftft lb* p*Uat nft omimulotlop klr load, dlvldad bp Lb* MlUplt of U>* nal*> of tb* rat* of rxrrrtk* *aod bp Kt/TA. ftad la aod raft** EDTA ba* aid b**a tad Uat loop. m. turn* L arj_* x ip: YftaCrrdap. Dr. RatalM Mapbaalaad tb* Importaar* of lb* rllalrlaa ccawidrrlaf al tb* dlapaattit poaalbllltt** la a bad oxpoaar* caaa, tacUdiap aoo bad roaditboa. t bar* two ow la poiat la tb* baftpttal ripbt to*. Tb*7 war* ofwrmud opoa vttbla tb* but Mob. Tbrp batb pr***trd tinax tin* a* "tftddrtp" do* to bad- Tb*p *m fortooalatp B*t frofta oar plaat. la fact, wo bar* ***** bod a caa* of foot-drop ta oar ao* atorap* batlrry Tb* placaa *b*rt w* m noot of tb* partpfcrfal aovritU bad pabp mm -- tbftf* ar* aot mp snap of IbM. I bar* probably toft oadp ala ar otpbt -- bar* b**a ia tb* bna fottadrb* obar* tbor* b a bap-coatlaood low repoaorv, orftb a loo bnl of bad aboirpllna Oo* of tbio* raara oat a foraar* charprr la a ftftftiftltir arblch oa* Bub lap op aid aiabil batt**r ptaba. Tbcftipb it *a* a ndalirftfr taJ aprraUoa, tbrp aauaRp **r* abb to mrlt op to* or Ibn* of tboo* bip cmltrmttrr bad* of------ *~if battorba. Tbrp bad oalp *lpbt or It* RMft nfotif TbU otpooor* oa* a* lalra** at lot. boo***r, that at oa* tin* I uroftt aiodid tbot tb* plaat b* rbood. poftdlop *d**uat# rerlarrrlap natlbtloa. Tbrmftar. tb* r*oo *r* aot **at to an Tbrp ar* *110 I* oporatloa. with ealp a fair aamutt of *aria***iap raatraL Oao of tb* atft I bad (Irut on la 1M1 or 1 HI obr* br oao rbarptftp a aawitor froc* a ftoull acaffcld. oltb tb* foraoo ** latou* tbot obr* f oat op tbor* aUadlnp orftt to bln. I coaldal or* bln bftcoru* of tb* faawu tbot **r btootap berk ftrrt of tb* farnar*. laald* of to* or tbr*o nlaataa, I oaa Ufttlap |d*ntp of *< bod. Hr fttUt bod Irrft ovrklar tbrr*. aad b* Itaattp dtbpd a Mdnp Hr bad Irllltf around fftoa oa* boapltal to atMiCbar. Tbrp (r*t tbupbt br bad * r"li*l porpbprla. Hbra br Ml AaaDp atat to mt for rtftluatlua, I Wllrtftd that ba bad a mild fn4 drefv BM*t tlkatp oa Ut* boat* of tb* bod abaorpllo* But tbrr* **r* rartal* oaparti of tb* tar* that dtp pot Him (bar and that Hft oa* bavtap tamaalap parootbaoia. ar Burnton**, and eraoil up araaalioa* of bla boor bp*, rxtmdlnp up toward lb* ebuftt. ftrttb a rmrtrirtioo dlrtrra* fra* tbr rplpafttrlua ripbt tbroupb to bU mld-Wk. Non* of that aooodad Ilka bad to m*. Iloarrrr. o* did trtal bin for tb* foot-drop ftrttb Vrrere* Intratoaoftftaip. Wltk tb* rorsHaot lorrraaft ta bad axerttUa, tb* foot-drop dUopprorad ootlnlp. Hooorrr. bo atlll bad Lbaaa otbrr apmptofta* of paraatboai*. m o* bad aqrrhfrxn don* oa bln toraaaa I didat want to tora him out. Tb* bod UabfUlp oaa or*r ftrttb tb* rbartap of tb* foot-drop. A mprlopraa ftraa tbao doe*, aad or foaad a apoco- ocruppiap btioa fran tb* foartb ta tb* olxtb doraal ftmrtrbra. A MUrofturina eporatrd oa bln tbit o*k aad fouad a lorallwd aracbMtdh tb. Tb* potimt bad bad trmUd laa* ta tb* paaL Tbla ftraa *o lorallftod tkftt It oaa btftaftdaf to plocb off tb* ftpieat cord Itftatf. That I* aw coo* ofcaru, if o* bad Mt p*b*d tb* dlapaaatlc prucodun* nor* or loa* I* tb* alb drprm. pmtoblp amwbodp ftrooid bar* aili a (lain that tbla aatlrr altoatloa oaa da* ta bla pmrbo* loam tkarptka. Tb* rptraftaa ftknoftd rualtp a loeaUrod aplaal card ho loa aandotod U tbr ocrapatloa. At lb* aaaw tiaw I b*v la tbo boapltal oootbor aiaa ftrttb a biloioral foot-drop. Tb* attradlac aroroloctat fait that It not b* dca ta bad. Tbla mao ftrma a baatrr and told an at pTftat baptb boo bo ***** ***a botbarad to alft tb* bad abat out af tb* dack tbot ba hiOad and feta, bat joftt aaaHoord It. had ftbot aad aR. Ha oa* ftlro oprratlap a wall aim* rattlap amtka. obor* b* aaad a Wad-coetaialap labrtraat *a bla marblaaa. Vbrtb** that baj ftaptblap I* da ftrttb M oa* qaaatiooabK bat anpoap. ba did ba** a bordrr-Ha* blood aad aria* had. bat m fttlpplrd c*th aad *o bad 11*0. Ho c*r taialp bod a foot-drop, bat tbr* ba bopaa ta dnolop oookoroa la bU baada. ta tb* oxtraaora. I atpoftlf bar* ***** aara a anadriphcta da* to had. bat bo bad bora rapldtp drroloplap that la tbo Uat fro mob*. W* aha did a aapdopran oa bln. Wt fouad that b* bad crrrkal aad h bar dlant. Lator. tb* corrkal dlac will b* raamd, oltb pmbaUr rur* of tb* paadripfopU. Tbor* oaa aaotbor nun obrr* tbor* ftraa had la tb* baokprowad. If or bad aot folhnrod N tbroapb Uraw* It appoarrd atpplcol for hod. 1 on aarr tbot lb* l**ar**r* rarrloro ia both ram* oould Karo krrx paplap prmaaoat total dual-imp Mora loaf. Yaaiatitap Dr Hard/ pk* of pluiaUan aa atif brtop puarrit la mudrra Induatrp. I car* taialp ototd ftprra oltb that. It atm aorta* |* tup up la tb* moot uaaftpotrd plana, parttra< i 1# ROUND TABUS 71 iw i Hurt lun bM In my npwlMK* U the lut In years Om u scrap paper dealer with only IPt m man la the shop. II turned out that he was Letlny pepar which contained lead arsenate from Marty Insecticide plant. When be Jumped up and down Is tba press, be stirred ap plenty of land duet, with raaaluat laKalalloa Booa this petieot wandered Into a hcwpluL Krtxdjr lw whet was the msUec, be was ao confused. Maatwr. atua lha technician la Um hospital found 400 stippled rede par M Baida, aba told tha resident* Ity bad better loch at tba patlaot'a (aaa. They Ibaa foaad that ba bad a land Uaa frna aar to tar. Aaotbaa sorb caaa of umueparled land abserptio* ** frees aa eifht-maa braaa foundry bora tba boas hlaaartf aai tba Brat ana to fat land polmalar. Ha bad maty atipplad cwJla and a hod Uaa- Tbara oars Baa cnees of land latoaicatiaa -- load colic type -- la that etfhlmaa brass foundry. They bad just stnrtsd la pear braaa. Iboopb they bad formarly pourad alamiaom. Tbay knew aotblaf about tba fast that tbsss wan load la brass. Aaotbaa small shop of drU or tsa poopia was maklaf aa "anfrso* lubricant. Tsa may tel bass board af that. Tbay bora betas la breaaa baartafa and BO tba botes wtlb sosslhd "SIS rvstoae ottfras lebricaaA.*' lacorpormtsd la a waa stub, lavustirath* Boaty showed that tba labriraat aoolalaad POV hod aside. 1 bsppsotd la saa Ibis casa aftar tba maa bad died. Nobody bad nay idea, naa tba boa, that tbara was bsod la that bsbriraat. Tba pallsat woatd pot tbia so a laths aad smooth It doom with a Bla. btewtaf tha bod lubricant dost directly lata bla fara. Tba man waa arbsdvlsd to have aa oporatkai for brain tumor, before a blood neat revealed maay stippiad tafia and Hess stody also showed a marked hod Uaa eat tba feats. Tba maa died A few boor* after the eperation, and tbaa tba orcepotioonl aapoaur* waa suspected. Tbaa 1 wu naked ta Inrewtlrete. Hew, all of theoe Inst three raasa bad land Uoaa and atipplad tafia. I think this under-worse tba Importance of conaldarlaf tba romrmmaat type ad bad dlamceU, sn* tba simple methods ad stody for bod Uaa aad stippled fetia. Land poboolaf. marb of It ntuepeclsd. la certainly sUU with aa. To mnclsde this soauoary, I belters that aftar a careful teoaidrreUea of history, tarludlaf erropatloaal blelary aad * plant leer by tba doctor, Uf<ber ottb ityskai asnmlaatloo, luoklnf partkalarly for a bad Uaa and ttippbd rails, and area qu*lltillvv land stodho of blood aad arias, I stlO would make aa urfsstl pb* not ta throw nay wry ussfsl dtancwtb tod sal of tba Window. I refer especially to tba stody of tba atipplad tefla, which baa bean used for many years, and la at(0 used la moat of Earope- I know that sack study baa rocustUy bee* celled aa antique method, bet whatever method b used, whether you uee stippled refla or quan titative bad la urine or bknd. 1 think there are two Important thlnje to ba considered. First, then* studies shooid ba does serDHj aad fre quently ; and second, tba physician hlmeelf should study the actual work exposure of tha CHAiauax Poworrc*: Are tbara nay comments a* other peperaT tea. scTHtim j o h mp o m: Wltb raapart to bhallay laws, a point that everybody knows perfectly won. tot It ban not bee* expressed at this meatlay. aad tt mlfhl Just as wsU ba tacked lata tba record -- much has bean mad* of tba fact that yen can understand and believe tbs Uw, aad comply with tbs law. That Is srbst Dr. roulfsr said; bat yoa base U demonstrate food faith. aU cd which wo understand aad nyrea lot Tba fact roiaslns Hurt noea, or all, of than* three thinf* accomplished, arffl let you off. Tba beat that bbetlaf does for you la to provide some rvidenre that I* admlealbb I* tba trial of year mao. aad tba jury trill decide how mack wvffht they want lo firs It. last a point that it Is M prints facia sotdeems that you have absolved yoontlf from all Uabflity. You merely hasp sinus drfsues that you ran preset as ctMtset, aad the jodfe bee to put it before the jury aa food evidence. I bare two additional comments ao tba labelInf af paint. Childhood phunbist la foaad al most carlaelrtly la alum arsaa whan lead cootalalaf paints hate fnDea late a deteriorated state. Potaonlnf rarely occurs whom osrfaco* are maintained in n food state of repair. Libel ley of paint! win help 'do-Jt-youraetf* (areata and bians owners to select safe points far In door serfsees, children's toys aad furniture. Laballnf srill not Solve tbs problem of deteriora tion. If rommoalUrs wish to rsdoco their IsrkSenra of chUdbood pluinblsm, they mat orkaowlsdf* and Impleansnt tbs need ft metnlaialnf boons* In a food state of repair. CM s u ms * p o w mt c m : Is lhar* any farther dim ruseloo of this latarsstlnf mbjsrtT If ant, am rom* now to Dr. John#too*1* "Comatoa Error* la tba Dlafnnals of Phnablsm.** ml fuTitxarcM r. fomrrroHi; 1 am ant fednf to rommant oo my paper. Them waa mteofh. Hal I would like lo ask a question which sksas my profound Ifnoraaro la Ibis tblnf. ta Induel ry. aa you know, encephalitis from InysotUn of lend Is no problem. I weal >omi o m In IhU audience lo otplala to ma why rklldran fat ancaphalllls by lafsetlo*. Our trouble ( Industry, of couraa, ku been by InhtUUoi. Wr Hat* Uh rvmalklt thin/a. you underter.tt Pi# tmm4 gue#tlon I would like to aak la. In what kind of caae 1# It frit necce- #*rj to ai# CIITUT tm- /. 1. I'HIwU. }*- . Dr. Johnelcme, (hr xxrretio#i of I#*d In the fere* of three children raa/e* m hl*h *a 100 m/ f Wod par day. Thla U (r# In 60 time# tkr nlm tor la- duatrted tj pee of exposure. Tlx Increased lad dears of k u U rtcfliakf>l)i/ In children u rtcr.pared with adult# depend*, it least In part, pen their Bon Inteoae lend Mpown. ~ M. t. K- inti: I binat awuend oenrty u luajr o h * b* Dr. Chlaelm. It certain!/ I* tree In the few chip* I hare Beuend that t hare aewa children ret. It 1* quite obrtoua that the exposure l* enornaoo# Whether the child** (rentre taeffirieory of pH control and chroni cal b<nnewta#i* add* le the haiard. I deal heow. I had a feefla/ It did. I think the ex posure factor Bad he the moot Important one efnSL M. . B. anrrn: t. too, would faroc the opts- lea that thi* la a done factor ffiBuilf. We M# that aoane of the treat* of lead la the blood art eeir klrh a* weC. Chl*olni ha* already da- orrfbed the (tool fcodiara, and ruck Intense exposure I* apparent la the elide I *howed on the child that died. I don't think that aawcefdlbiUty I* particu lar!/ a factor ia term* of the central Herron# system af children. W# de He a roOecUon of dll Pane# loroltin* the neurolo/lc*! ) #lrcn. nbere a/e prnhahl/ 1* a factor beraaer Bt/e{lnl*atloa of the central aerroo* /tm ha*a*l occurred uaiil the latter part of the first /ear; but m/e- liaixatlo* I* pretty wrfl completed hy the time the child fit* te the are whea lead pobonlay occur*. ml Mexxirr Ka k p t : t *u wondrris/ H Dr. Smith could tell a* what amount of lead wae la the brala tiaese of that aotop*/ of the child, and other aotopaied children. 1 am rtli) inter- eeted ia the Idea that there U soma difference between the adult and the child la what the central aereon* o/oteoa doea la response te toxic laauK. M. an ml: No. ! am emburrsaeed. I don't have It an that lodirlduaT* *Ude and etlB haven't found the exact fire re. I Just bare It from Dr. Kehoe. It waa hlrh la thla ladlvid- ual child la other*, thou/h, we hare found that If there la Ire* than J m if toad per ion z#n of hrala tl#oe. even thou/h clinical!/ osneceie ha# aald there are Indications of tend encephalopathy, l>r. Kehoe haa been rec/ h#e|. (aat to make thla diafiu-#!#; and rei e#wh or- caaion when ho haa town la the position of dlf- forln/ with thorn of ua who were the clinician*. Ojr pnlhoiotiet haa found anothor ennao for daath. There hare beeei oereral oxamplta of thla. and I think the/ point to the fact that rrea thou/h there uaa a coo-ldcrsble aanouat of load la the blood and In ao#e vf the other tlaaueu, thla uaa a coincidental findln/ Is aaeodatlon with a dlaeaae which waa llaelf fatal You aakad thla mornInf how oar patholo/tat picked up thla dU/noal*. There were a couple of tblr./a that made him suspicion*. la abaoat an/ care where there waa evidence of arete cerebra! edema and brala atom herniation. Our patholo/l*la hate done two thln/e: on*, looked at the liver and kidoe/ far the Inriaahm bodloa that Blackman dewrrlbod a rood man/ /warn hack; and secondly, the/ barn cent the brala, or part# of the brala. to the Katterla/ Laboratory for their confirmation by tiaaee analyst*. The Inclusion hodlrn ore aoanethln/ that only make aa raapect that thla child haa absorbed excaealee amount* of lead. The/ don't prove the dta/naala of the encephalopathy. That require* the far ther step of cerebral tlaaaa analyst* far load content. ml HxKtiT: la other word*, thla la a Boaapaxff* Ir cerebral edema harla/ deeaooetrated expaaure to bed by lncleelow bodlea or It* |tm*at* la tlaeoe. It then remain* for aaimi to take the bold atep and aa/ the/ hell/ la/dlsr. I think It I* perfectly poaetble that childrun with enr/la/ di/rnu of reeehral edema ml(M bare qette aerintt* morbM rhan/e and phyalolo/lf ebairr diaturboace la IntWli/eoce quotient, or perhape /a blind If they lived, t am tatarwtad in what cauaea the patient to dlw, and whether It la related to lend la the brala of adult* an Welt aa Is chOdrea. I remember ao well dWueala/ the care of a Ne/ro maintenance man la a atara/e batter/ plant who had had food, aollf exposure and waa found dead la ht# bed la Ua board!*/ bouae, ad the rare waa bcou/hl op. Question mark -- lend poleceiln/? There were ataf/eria/ amonata of lead Id the brala. la the discussion, 1 waa the ceil/ one who waa wtllia/ to put hi* death and the fiadln/a of lead la the brala lo/ethor. How mock do you waal fa **/ that cerebral edema U leod-reUted? See what 1 am yettla/ at? I am *e/re#tin/ that tha rasa* af daath could hare bare heart failure, or rxr*#wire *dmlnUtration of Bold*. But when doao one aa/ thla la lend poteonlsa and tead-tadered death? I am not aa/in/ II weft, but I am tryla/ to fst *1 '.ha problem of be)*/ *o beullaal la any that lead la dolny dama/e because you don't hare aa many piece* a* you want In the equal low I mu#tn't l*l>e thla point tew much, bet | aee Dr. ftyrra want* In alrulfhtew me ant. ML htuut: I duet think I tan. I f '-V 9 :V'' ;J )& ML mu b t : the I Certainly when children die who hart clinical potholopical lead encephnlopalky. tbey die with brala Men cumpreaeUm. They die with ebwlnp reuplrattoe. pulae rat* aad Mood preeur*. anuria, all the eeual rvideam of tncrewaed cranial pnin. I uni brllm U>t tUi icol to aotaa n; related to laterfereocu with the brat* turn ayelema throupb aaaooeta ad land which Mr Ml U Ibmxt'M b* Impcic tire. W* tum*t a* many anal/eaa, I an aura, aa Snilb baa, bot Will 70a And ainouota of bad which an ratbf abort tba aaoal raa in tbaa* children. We try eery Hard to bad otbar rauaaa for daatb, W* certainly look for otb#r dlaaaiaa at eetopay aod don't dad tbaaa. Ml itiMT: Coaid m briar H barb to tkia ortrtaal point of tba dtfman between tba adult and tba child bnla la Ha rnfnnn to bad aa a poaaibia factor? ML irm: I tbiak 00* factor that f can't lb la 0*07 weB at tbb point of tba erpumeat. aad which oftaa b hot appreciated. la tba prowlh factor. I arlriaaOr pot latoroatad la bad ba> nw of children aha bad bad bad poiaoniap aad bod beta acat boo* from tba boapttal aa (and. who tbaa taroad ap la My eewroloptrml rttab breaua* lbey wan IthahtTiap la oaa way aa aaotbar. or not learniap la reboot Oot bid aa< Iba arhoolreoai a An. aaotbar aba bub rid bated araaad aa tba tot K<m of tbaaa rblldna bad , acuta fiihtilnallnp aarrphalltla. Tbry ail bad actdaooa of bad poiaeetap. Hk# atlppbd raila. MM tarrcaar la aptaal fluid, total paotrla. Cl aymptoma. coproporphyria la tbo arlaa, tblar* of that aort. At that tin*, arv dldaT know aboat tb* Importaara of eeparatlnp Ihrm from bad. Wo triad, la a doaultory way. to aopanata them. Maybe tro weren't tncroafal about that. Tbo point | an tiylat to make about throe children b that thoufb aoao of them. al taro or three pan, bad aa arete encephalopathy with their acute tatexxbatten, wbea they reached ala or aeeeo they aboued evidence of brata la* Jury. I tbiak that any eblldrea Itet chronic encephalopathy from bad, aa wed aa tkia acwta bualntaa. I think H b a qoeatioa of deprau ubara one morpau lato tbo other. Now, with treatment with EtlTA and with protect toe from bad. we dint aea that pirtero aa often aa wt weed la la fart, we herent aeon tt at alt la the tart tie* or all yean. Tbla rroup of children deteriorate* pradua!ty altbout veer haetap had aay acuta bad enrophalltla, and tberofoce I think that bad doea nor thtnp to the prowlnp brala which la different from what It An to the adult brala. ML Ktwi: Now I bar* put what I want. : I doat know that I caa peer* It, but certainly It arta that way to aw. Mi. Mkurr; Pcrhar* If w* bad eoapb apart* aieeit of adult aad child bratal in laad-poboaed ladirlduala, and knew aewupk abent tb*lr clinical coo re*, w* mlpbt be abb to aay thta. I tbiak it Ini Joel aa lmpre**iea on your part M. PTkaa; To try to ruble It only to tba myeilnUatloa deni mah* HUH bacaaa* Ih* brala la muhlptytnp a lot of thlap* (bot yoa cannot demcnatrat* bbtoloptcaSy, atifl tbaap* lap after myeUaltatlon baa terminated. Brala weipht lacreave* bap after yen cna*t dimno atrata aay ebanp* la yoar Ltavoa htetokxpicaily, aad bnla rrowrth coctialMO ip to IT ar If year* af ap*. M. Purr: Wo bar* daaa a few abetnaa* repholeprama la adult* with wall aotablUhed bad potwniap that nobody doubted, and than wee* chanpm on lb* *t*clro*nc*phalopT*u which mi reed without aay complaint* from tb* po* tbata a* to beodacbn No on* rould ** aaythtap urronp with tbo yu proeada. 1 think bod b t real aenrotosla all ripht. aad tb* tbnabob af prodaetbn of aynptom* from tb* bad tart* taunaoualy from potbnt to patlmt. Now. what Red really pot up boro for wnt f* And out wbea wa treat a rod* of land potioalap la ladaatry with EDTA. 1* that ripht? ml joNwyyDXc: What type af caaa. ml Makar: It h u m to aw that yea da waat the dbpaoab aotabllibad. ML fMMtMfi The dlapiuiab la mtallllkli. but a bat Inducea oo* to plea EtlTAt tn. Mkkmr: Ye*. Wtfl. thu thiopa that la* data mo to pic* EDTA art aymptoma wry bard, to evaluate btciiM they an enhlcvtlT*, toeaalap ebrook ccautlpalkoa. abdominal pela, cnmpblat of fattpue. What 1 waat la tb* way of labora tory rridrare b. If poaaibia, acme laririmmmtal bnowtadpe. I aoually caa pot tbb with Here*y Elkina* help, but If 1 caaT bar* that. I waat a lead uriae above at Imat i mg per Uter, aad I waat a porphyria that b ap. W* pet quaatitattv* tea la Benton, from both tbo Maaaacbuaetto Dlvtaioa of Ocrapelleeal Hy* plea* and tb* Maaaorhaoetla General. Bet let** have It at thro* or four piua, la tb* tonalaoiopy that we bare boon aatnp, and alee btmatnlnpb abnormalltln. And, apertAralty, urn* Indira* Iba that then baa been either dlaturbanro la hmanptobln ayatbmU or ertoal red Mood ref deetrurtloa. Tbla la pained nlmpiy by aa Iroe deficiency anemia or (be more elaborate itudla* of hemolytic effect, eurb aa cheapen I* frnplllty of tba rod retla. Thin* art tba Ihlnp* I waat before I treat a cnae with calrlum aodlum KtrTA. I have MCne heeltatlon about uclap tbla Bute rial I* pattenta I doaT know well. I new 4* Ty-_, :-V**E **;!-' 74 DISCUSSION kidney function atudy. aaperially U older wrtwl with Icof-tlmo etpaaura. My mrntl opinion la that w* have km murk too caaua) about tb# effect of land on th* kidney. I r*i excited by Dr. Chlelio'a remark that they h*>* bora able to demonetrat* mil lab our trouble* and phcephate hold Inf effect* In children who hue* * tot of load limit. 1 certainly boro i null ouokf, bat t Mbllo oumv--r. of mra rbo boo* bod Imt-lom a* poeura to lad ood vbo do abow rrtdrwcu of rani damage. ^- If 70a pat tbot together with wbot1 HafTy romM oboaad In expecttaaelal ulntk what tb* Swiat boo* flan, nod rartoa* otbor people, tbot if you do* tb* right doo* ood fir* It rapidly, no Lontlo don, gw* f* dnoti* In tb* kidney* -- tbra EDTA'moot oat b* tmd la pa- ttowta orltb rrtdoar* of rani diionoo. t think another factor UaT lead* to tb* derieion to EDTA la a\tfiicticol trajr I* whether tb* worker -- lb* patient with lead polaooiaf -- ran forrrer after b* free from lend expooar*. If. far nil tb* rwina nil of a* know, b* nay bn** to r* back to hod. ran odor lha boat Industrial kyrira* cimonatoaca* nod tb* b**t will to tb* world. Ibl* iiiim to b* a appropriate ox* for oldra EDTA If |M coo keep tb* man under nodical aaperrlaiea. I bar* bad coopt* of rupenriaora la atorac* battery pluu wbo bn** bora bo*pftnllwd with bo < too davaatoflag bad potoralng -- oad ao- body woold cbaltoar* tb* dtogaaato -- bat they bar* rot to to back, ood a eraloa tbey bar* tot a oew worker oa tb* pallor machloe*. They bar* rot to *0* nboot tb* natilatloa. Tbey bar* a lot f IMM for pattlar their braalblar ooo* obor* naf* timha of Ini Sorb propin I bail***, nay la nlalttid to m to fear abort coarata of calcium aodlum EDTA therapy by eel* ualraa they ora Buffering from non* rraal damage. Tb* other rraap of petSraU wbo praamt problem* ora lboo* with uncertain dlarnoao* of trod poUoalar. and Iboo* w hat* already dla- coaard. I bar* no healUlloa la repealing tbie* roar**# of EDTA by v*fo orrr ood eevr again, for abort period* at low doaaga. wltb attention to laboratory atodlaa of rant function. I don't think *acb trratmaat Carrie* a bourd If H I* rlron tltnrly ia tbra*-, four- or flew-bour tlmod do*** of th* order *f I gm to I gm, d*p*dlar on tb* wairht *f tb* maa. P*L joHurroNC: Am I ratlraiy wroof, nod d* I JeopardIf* th* filter* of a pallrat, by merely wtlbdrawlnr him free* tb* anelroomratT kfy daurbtrr* nlway* aald that all I know aboat therapy I* In put a lUnd-Ald oa th* guy If there I* *onvthlnf armor on th* ovtelde, nod (fie* aptr'.a If liter* l* aomethlng wroof pa th* Utald*. That I* about that way I treat load pulaonlar. Am I wroeir la withdrawler tha maa from aapoaura and traatlnr him a* I faorrlbed to my paper? I* th* future of that maa Jeopardltnd In nay way by not firlctf him EDTA} U It Jnallftxbl# t* pat a *0-called minor caao In a hnapltal and rwa up tha expeefo* of rirtof him EDTA} la other word*. I* tbla whole pblkoaphy wrung. of dolor wbot W* did before, baiiaetag pfcyaldcglcal mention woa tb* fuadaamtai thing. and eboold W* p oeer to tbU EDTA ahnoat routinely, eliminating tb* tblag* yo* aay about tb* kidney} to Knurr: I certainly think that If a maa ha* been expound for ten or It year* Moodily to tb* lobulation of bod. kaa of h oboe* th* woW aof* limit*, ood If Ibl* I* ruEactad la hi* Uood finding*. he can b* aald to barn bad Intoxication. Each caa* la 0 caha by llaatt. and anybody wbo ******** that EDTA ba ward rauUaeiy to, la my Opinio*, la arror. r*. ntoiiaa lamtdt: I want to am* with tb* thing* that Harriet ha* Jaat aald. Ia tha aarly tad at our anthualaam far ualar EDTA ia treotaarat for vnriooa kind* of potoonlag, tbarw baa bera inrarthlnr of a tandaocy to flap tb* *umber* ram*. It I* putt* aacunragtag to ueo th* ancration *f lend of plutonium lucraaaad by a factor of 10 or 10 ar M, and inrymi la tb* twapital atoad* areaad and chain Whan tbaaa aambtrw cuima aot Tb* fart raeaaloa, 1 think. that porhapa wu bae* mad* only very amall Impramlon an tba total tody burden. Tbla coma* back to what Dr. Jobnetone Jut aald. t> ba damatter tha petleot'e chance* by failure to (Ira EDTAt I dooT think m. 1 think that a* far at land to concerned, tha mot ralu* f EDTA to la tba railed of aymptoma, nod to tldlaf th* pa tient oeer a temporary mark *poL I meld add one other eery aaniH point. Harriot mentioned that Harry foraem* daman elraled th* kidney darner* la aaiatala. H* deaaonatrated It la animate after w* bad already deowaMrated It on a human. a caa* that wa* quit* w*0 worked up aad th* atory pabUabed. . w. c wudKTri I am glad that Dr. JohnMon* mad* aomu mratloa about th* kind of raao whora you would uaa EDTA. Elrat, 1 would Ilk* to rlee yon my Introduction to EDTA. A rapraaratatlr* of a company which **t|* It ylaltod my cfVe oa* day and warned to know If I wa* ualar It. I told him an. H* aald. -Why botr I aald, "Barauea of your marutne ndeertUaenrat. I don't Ihiak il la a food thing. Toe haeu atatad that K ehould b* u**d prophylactic*!!*, a* weO aa la toed poUnolaf llaelf. Until you rhaar* that, concerning It* ua* prophylactic*!^, I am not going to o* Ik." ,:;*r-V^v^;'^;^rv:-;; '.^.'-yv-f 'r T~ . '/`* - y* ;>'.*/>.: ; /,vI T *" J - .n a ROUND TABLX 71 If pun wtO took it Dm (tmtlmnt pew wtB im Ult it hna bna chopped. Tlxf cliuiW R about i month or ao Utr. Tkm U on* thlnf urn about tbo point of EDTA'* im prophplirllcollr, which wo* brooffct out boro loti;, ut (hit ta, br ptrlnf EDTA pou c m produce i Nr.M of folio Hmritjr- Then b ao owoeUon about It, ini oorthlif that will do tbit moot bo not cuutlouet;. Wbit I bin boo* Intonated ia oboo vtng bon todap ld peeterdip *u tbo ueoetkm of what bu hippmd to our calcium thonpp. I iai lira tbit to what Dr. Rotknap bod ia mind. I tblak t>f. Kofcoe would boro tbit la mind, wen bo pnoiat tbio afternoon. I ban board Dr. Shlpaaaa ulb iboot relief of epmptcww of load poieoalng. la tbo woo of EDTA. Did pen ever aoo anpthlag ao iporloo* tar la poor bfo ai tbo rollof of tywptnn bp fifing latraroaoao calcium tborapp 7 it to lacrodlblo. Kotblat olio baa oror booa monufactand tbit caa give pew tbit rapid, opactorw. lor rollof from apnptwua. Wo ban wood caictum tor paara. Then. io ao tborapp that I know of that boo booa pmcod to bo bettor tbaa tbo old-foohtcood catrisa tatranaoaa Oar Malta ahow It oror tbo penra. I bin 71 to iO load lataoicatioa cam rtfbt mo . Too caa no toy point of rirw. I am penoaaQp, from atp own ooporioaco, etIQ opalaoC detoadtap. t fool that It ta aofef, aad nan foaolbio, la let tbo doioadlar procooo tako IU aotoral ceune after paa ban lottn tbroofb wttb tbo ante ton I deal otato that paa caa jut Ipaon tboao arc wba an yoo*d. Seuwbodp (at tbo Idea bon that ora an pat treating tbeso aoa Tbo doctor* arbo opobo tadop didn't waat to (tro oapraco tbo Idea that tbop an not treating tboao acoa wboa tbop oap tbop an permitting them to axrroto tbo had aotaraOp. 1 om ton poao if TOO orut tint, borooM paa da treat tboai la poor m porticoUr faehtau. Aad paa |r< waaderfal Malta. I am etffl o(allot doloadlnf from wbat I ban beard, partlcoUrtp after what I ban board aad road abort EDTA. I would like to vt oao woeeUoa of pea. Dr. Hardp. Da paa people la Maeoerhuiotu (o ofitlroip aa porphprtn tooting ao to whether a man bn leod poleonlng or oeriauo load oopnoiroT Tbit U wbit I bin bon lafonacd. M. Ma ip t i Wo in nrp much Improxcd wMh tbo lord of portdiprii oorntloa li tbo arlno II || lodeo of tbo liter*Iratloa. act tbo rtpocro. Tbit li tbo point. If pou biro a whole (roup of people la tbo otorifo bolter; plonl wbo *bnw a wide opoctrum of Ud nluoo la artmi, tbo porpbptin, wo bon found, whoa duoe quaatltatlnlp, (ina a (aod Idaa M to who la t*lt| to tun ap la the alek bap. 1 would llha ta guami wttb paa aboot tbo two of calcium aa tborapp. pa. wtLtKTl: Porphprtn, of emm, la act aa tbo program. but I know anon who crack la had plant* wbo bin Urpo pocpbprta oxcrotloao aad boro levee pottoo rich. Of couroo, I ua oalp talking about porpbprta ci*a, whrn everpthing eiee U orttbla aortaal ihaita. ML HattrT: I tblak wo ban came to a eerp food area of dtaagreemeat. ta. w iix w t c : Wo ban rocordo ta aabotaatlata thU fact. pa. aaasr: A rood boahbp ana. Tbla la tbo am when wo oood awn ianetlgatloa. I tkal> leape tbo ceaewpt tbit It U all right ta lot aw walk aroaod wttb ladicoa of patbeiaptc phpaMopp, wblcb U wbat a blph perphprla ta. whatever It ta. bocaaoo If It ta doe ta akabol -- ao Dr. keaalkeff waa eaptap pntordip aad which hi* booa ibowa pear* apa -- tboa mapho uai tbiap baa to bappoa about that; bat If paa pat It wttb taw boaooplobla aad pun baaw tbo load aa. wiuom: That ta dlffonat. M. um: That tat.' pa. wuaXTt: That da dlfforowt. That baT what I aibod pun. If paa pot high porpbprta nenttoaa with atbor bud atpaa aad apmgdeam. tbit ta a different atorp. I caa (hew pou tkno or four doaoa cam af high porybprtaa. which wo oUonid. that bd ao ladkatimw of pptoow or alpao of load Intoxication. I am aot talklap about taw hwaoptatJa. taw blood coaota, or blgb atippilap c u mo . pa. pun: Too aad I would bon to aot ap tbo otaadardo of hod tatocicalloa ao tbon ta aretoil opre meat. Mp goarrel wttb pou oa ruletom tborapp note oa tbo fart that calctam form tbo load Itrto tbo brmp drlrlM, rotboo tbaa out of tbo bod;. And oiocw tbon ta a UmH to tbo (mount of bad tbal tbo obototrm ran bold, unboo the b u m U pormnatl; ncaoood from load upoan, tbo ritk of load poinoulnp ta lacroaeed. Am I aot correct that forrtap load lata tbo bone with cmhlam ta tbo baota for tie no ao tborappf pa mom: Rlpbt. pa Run: The look toad goee lata mw form of phoophato aad dloappou** la tbo. . , . ML wruaxTJ: Moblllml MoblHm tbo load wttblo tbo bong (tnrtun aad taboa tbo load out of cirvulatlea, tbuo piednp tbo bndp R rhann to like a "breather** and pnpan foe the neat (Ur*, which 1* the etrretlon of hod bp normal, Mlunl metibnik and pbpotoloplc peuco ML H**nr l)r. John*tono want* to l<Ca pa iONNoTOMR: | think, Harriot, pou ku a dimm olfht more about tbt* tbaa I da 7* Dtsct'MHr'f j ml ma is t : I do moL ha wma plraa two Ubbda of EDTA hp taaoth. ML JOHMrtDM: I think actuaTy tha ooly ml Haaar: Half-praaiT ralu# I found la calcium to that It rolln** Ml ria>: Half-pram taldeU, aaa t( hoar* tha pnatrcdalmllnal Ipua, lif matabuiirra. after tha othar. Within It ham. ha waa pot- Doll forprt that. tlnp out l.ViO alcruprajna of bad por It ML aunt: Oar fiM w aayla* ha wM ban la hla arioa. HU npirtal Avid total pro- talker la enkl-m and put tha land back la Win had porta up to 400. Ha wa* aaraurlona tha boaat. I aaa QuarraUaff irttk that- I talak aad far rtambtona, aad hla coproporphyria * mat tha land aal arat way up beyond what w* could maoawr*. ML wnjom: It la mcmtad antnmlly thara- Va than put him on latraroaonr EDTA and attar, la a ataqda, palalaaa and a&claat pco- thlnp* talmad down, but ha haa bran prona- coan. V arwtly damapad by thla. That la, h# had damnpa, ML MMDT: Da va taka tha ana aff tha M>? kirk War not meeaibla. la tka brain. 1 think Ml iriuxn: Thara ara not aa aut, not IhU drop rhould aaror ba plraa by mouth. U your plnat la rualljr data# a >nh. Ton m- Tha Utrr thlnp I would Ilka to petal out aaai ma* a baa you haaa la, and watch tha la that bnforo wa pot lato tkl* laaaa. wo woro other* aa a procwotlaa. fuaaiap with oral EDTA la children who had ML ttaamr: But with atractaral ataat painter*, brra Iroatrd bream* of load poiaoalap. maatlp far lartant^ that* ara aaap land npawn With anrrphalltla, aad wo had pottap about a wham It Is M pimple to nattd tha haaanL dtaaw cblldnw aad w*t* aur* wo had aHmlaafad Va ara dlacwaainp a tary coeaplkalad prutoli m. thr bad from their hrmwa. V# put half of thara and that la alp. aa you my . thara la an aaap on oral EDTA. a pram a day. Tha othar half wa pcnphytoila, an ronlina hnadUap. hat aarh raw bfl aba*. S'* trantmaat at *0. Jad fuflootap la atadKd and tnwtad aa It am tha artnr qualitatively. aaatap thara hi tha Ma c a m. VALnxa: I maid hka to aak Dr. haopllal oara la two work*, dolar a puabta Itardr it aha haa Una able to haap tha latronrw. Ihr lard far coproporphyria. Tbb praap f aaa t*]*rtiaaa t EDTA la* aab la natal to chOdna'a coproporphyria <*Uy*d pooMivu any- permit tha awa la raatlaaa aa tha hh nr aural wkrro frtoa four to IT awatha. Than* ar* thr warn thap ha toapttallaad ar takaa ad tha Job? oa oral E1*TA. M. lMt: Va laaiat aa tntlar thrar ad . Tha raw* otf EDTA ran copropwphyriaa from tha tab, far atadp at maal faartiaa and tar faar to 1C month*, aad cortataly w* didn't pat . tatnnana treatment with KUTA, rd of any moeu of tha bad from tom kp (Ma w ML wtlTtkr: I know af naaa datot aha ar* onJ * of tha drop. *0 that tha aral aa* of tha dtoprwalap tha EDTA tablet* orally aad prnatt- drop b laatrcTtlr* aa wall a* drape con*. tiap thr rwiplwyr** to rtatlaaa worktar. hat 1 bar* pot to pa, I aat aonry to nay. Thaak aemcime raid prMrrdap thrp didn't appcwto of you trry murh for Irttinp mo la. that. Da t*n appro** at tha aral admiaiatrattoa otMtMth hoatvirn: Do** that tarmtaala at EDTA? thla phaar of tha diacaaalow? ML Ham: Ka Tha effort*. both (and aad If m wo com* now to Mr. Vatara* "A Lawyer had, ar* aat undrmtood. Atanrpihm throuph Lawk* At 1-rad." Duo* aayoa* want to nay aay- tha pvt of Wad rwabiand trtlh EDTA b a pad* Ibiap atom *l-ut that prraawtallua? If aoC wo hilitp. Kobdp rrallp aaitorrtaadi tin. May bo come | !>r, Daetjer'* "Tb KITart* of traraa aad noma bad |*t# lata lb* blood aa It near* throapb Temperature oa Childhood Tlumllam." tha latentlaal oak. Dr. Itartjar, would you Ilk* to add aaythiop Iff. MlDar pa*a tha rrar aplaloa fa* adalt to whal 1 mi raid thla moralnpT bad potaailnp. Dr. Bialik apmod far tha chll- Ml iktt MITlti: Dr. Bhljunaa ruppmhd at draw, and I held tha raraa tlr*. lunch that wa ta*l tb* idarta of lomporatnr* aa. tu: I rpta lkl noralnp at tab, m yxuap animal*. V* ham alroady prrfarwmd bat It la tach aa Impceaatm dmuailraUoa ad eaparimml* oa both youap aad aid animal*, aad what EDTA tor, ptira bp Month with bad la w* am dolnp atom reportmanta. Tha apt auparb tha pvt. that I think It la wortk potttnp aa tha manta ar* M yat enmptot# anouph to report. board. nutation aowMirn 1 V* com* now to tha Va had a kid rmna la with mild Irmd polwmlap. lw* paper* I* EDTA therapy, |>r. Mltbr** aad Whnar blood bad Irrrt wa didn't pat maaaolrd, |>r. Brnith** Am th*r* aay commaai* oa thorn? tail who had a fairly hlph roprmw-fphyrtnaria, Ma r. r Mt arMi: t am not a phynlrUa. aad Ibvl 110 la tabroprama par dap, had *1 Ip- I hat a toon anllphtaaad la tha ta*l two day* plod mtU, Had iplrrl Bold total prrdata of HQ. and r-mfu-ed alo, | would Ilk* to hear arm* Quit* roAwh-u* Ilia bod output an* m*a*or*d MHrr d-ri.^'a a# |ha ara af EIiTA la for tt ban; aomnd 2tb) aknriunr par It diartonu that Dr. Hardy haa bftmphl nut. hour*. At tha and of tab period, bp mlntaka ML IL r, MU; ll U poaalbb that a proioca- Iistfe X- t ROUND TABUS tlve bad rxcretioa atody may bt balpfal U determining that * mon Km u axceuelve body tardea of load, when lSo u*u*l load atudk* do oof rrml thla tarda*. I'ntll aarlj IfW. wa U Colorado brUmd. M moat other*. that I men did oof bar* Uad poUiuilnf unbaa h* obowad aaraaalrv amount* of bad la bla axcrathma aad blood. Kariy la |M&, Dr. Sherman Pinto rafarrad a* uawal caaa to u for dlagnoala aad cant froaa a had ameltee plant tocatad at 10.040 fad Tbla **-yeor-old mob. a 8punish-American, bad soar ta* yeavra of eccupatkmal load aapoaora, aad daring tba laat eight yenr* of that Um* ha bad bad periodic urinary bad atadia* Ibat aariad la a normal rang* froaa tM to 074 mg par liter corrected For tea day* prior to oar erring bin. bio CO* phyalcia* bad glean him lb<4 gr of sedlaaa tbioaolfata latrannuaaly dally. with *o cbaaga ia kia coaplalatag of baa of tba aeriltf aaa of kia boada. aad aumbarea of baa focvarma and band*, of e*a month"* deration. Ha dmbd. and tea wara oaabb ta ab bi*. aay part blatary aaggaoiira of bad pet`*e*i*g. rbyeical axamlaatto* maabd dilaln' Uo* of kia bft palpit, waakneaa of bla bit dtoak. a minor bad liaa. gauathq aeeatkaala to bla aiboon. |m ad deep tandem rvArxeu I* hie fureorma. weokneoe la bla focean* eupino- ton asd pronator*. aad aa inability to mend bia mrtato aad Angara. Laboratory oaanlaatloao eboirrd a normal aplaal Bald and normal bidaay wad brrr faactio*. Tbb man htatrad a moderate brporkroatr auMuaU. with a bean giobia of 11.7k rm. Tba atparted normal, at 10,004 frrt ahltodr laj.1T gm. There au no baaopbUlc'rgitiptdlng^ nor rattcolocjrtool*. Ilia i;; nblU.-ptiljfluiraa U.T04,iritha normal dilfer- oatiaL Tbe bkod bod *** 0.07 aig per 100 gm. aad bb 24-boor ariaary lead raembne ware 0.0* ng pet U hoin, tab lb bia dally fatal bod aacrailoBM varied between 033 ng and Mi mg par 74 bourn. Beceuae of tba typical ararologbal BadIago. -aneavla aad bletoey of bod anpoaorr, wa audo'a pragmaptlr* diagonal* af land poisoning, ia aplb' of tba nlatitaly normal body tardea of bad H reflected by bb Mood. artor and fetal bodtoateata. After frar dally Intravenous troataiente af I fM of Ca KDTA. there woe ecana raiara of bla forearm deep iendcm rWbtuv bo maid extend bla Hagen aad wriale toiler, knd hit gaantbi parenthesis, Inequality of pupils. facial paral- yU aad bod Una bad disappeared {hiring tkaoo four daya of prvilminary I rootmerit be *arreted Ml of af lean After three month* of Iftlornlttoal treatment, with k Iota) d do yea of infrareo.oia Ca KDTA aad 47 gm of oral Co F.DTA, thin man woe cllnkally com pletely wet] and raiurnad to kia former work with ao disability. 8Inca Ihla cone. oororal almllar caooa with normal rnnga preiraatnaai bod atodlao baeo Coma to oar attention and boro been treated with Ca KDTA with equally gratifying rueoltx. One case woe surceoafally treated with Ca KDTA la IMT. where la 1VS1 with the a*ma mmplainU wa bod auggaoted. but bad rwfueed to make a dlagnoalt of hod polaeclng bocaaao the patient's qualitative body fluid bod otadlm more wltbia what tea. aa well oa other*. the* conoidared normal lialU. (a tbaoa case*. with the dramatic malaria* of aymptaca* after Ca KDTA. lb larraoae la M oarratio* woe ala* dramatic, ft occurred to m that (a ccftala caooa. arbor* rabtiealy normal bad ttadiaa art found, with aynptooao ponalbly rmnpalibb witb bad lataaicailon. * provocative land omtfa* Hdy night be of rate*. To do a 7 gm Ca KDTA tatrareouao proeocatlr* teat aad rollert a 71 bar aria# aporinoa la a litlb rlumey Kb* m etadled the paye lltlooed eimtlm *f bad I* * 71 boor poriad after aalag 3 gm. I rm, aad fl.1 gm af Ca KDTA latraeonooaly. w found that tb* ranuloUrq perreat of ICtar land fimtica after tba and of tba iatraeenoaa lafaaio* af Ca KDTA. betwre* tb* limlu af i U 'gm aad S gm 4**A felbwod a vary reduptlrataU* rarer equal to 77 4 bg . when f b tb* Urn from tba rad of tb* latraeaamaa tafoale* is boon. A pro lifeInary study of tba Inrreared amount of lr*4 excreted after a promratlvo tad with t.l gm, 1 gm. aad 1 rm. tit la tb* ratio aa t U to LA b to AS Ibm, raapactJvoly. Tbb anoa* that U tlnao a* much bod will b* excreted ia tb* aria* of aay partbolar tedhrldual aflar S gm af CITtlTA aa win bo oxcrated altar 41 gm .jMlBl iadivtdoob wDb bad rymptom* and a hUtory of rapoour*. aad compand their raegakbaa with aavoral normal subject* witb aot^napUma or hb^oey of bod aapooun. before ead after treatment irith Ca KDTA. Ia tb* bodaxpoead ca***. the ordinary 14hoer arinary *g. cretimo-of toad often overtopped th* aomat etodle*. tat * distinct, Mparothu af tba aapooad aad ao*-axpond growpa could ta deter* mined from tb* amount af tarrmoad 74-boor bad oarraiba aftar t gm af C* KDTA. From Ik*** atudlae wa bav* tentatlrefy derided tbot If th* Incraao* la th* 74-h**r arinary exc retie* fft't I gm of Ca KDTA iktroiaoouoly b nor* tboa 13 m, the* it la praaonptlvo that tb* Individual bau mar* than a normal tarraair la hi* lty tardea of bod. If tb* lacrena* I* bn* tkaa *3 ng. Ihe* h* pr*eum|41r*ly darn aof bar* an atmocmoi laurooea la lead body tardm ( lurioralliely tbb noana that after 0 1 gm of Ca KDTA talrawoowly, whkb ca* ***lly be given Iron * e/rlng* k*d rather rapidly, aa rt r -. _.- . >' \\-i-` .;'.'. - - ; . ,.r --------- - -*-* ^-?-- 7B DISCUSSION IwmM of OM mg la M-bw iriuir M ex cretion would ba presumptively positive, aad laae than OM my would bo preeumptivuly Mfv lira. You c u b mu that with the 14-hour rumuUtlru percent cum, a pmoatlrt last eu be anally performed la aa efftre under controlled superrUlou. A au wastes hU ariM la a bottle aad Immediately la flrra 0.1 gm Ca EDTA la 10 oc of water Intravenously, aad tba akaet UaM acted. Tba patlaat than doaa not told again for tbrua to ala boura, aad tba tbraa- to tia-bour apecimro la cuOactad aad tba caart time ratordad uadar dlract euperriaioa. Tba amount of hud fouad la tbla specimen la tbaa currartad la M boura oa tba cuaulatira percunt rum for bia It-boar wntka. Ia rootlotion, wu bellm that a provocative aarrrtloa atad/ ia of ralua uadar earlala cirrumstaecm, but that coaaidrrubla atad/ aad cor roboration art aaadad batora It <aa ba accepted aa a caitarioo la land somyo or diagnosis. Oaa word of caution -- wu baau fouad that if tbara baa baan racuat treatment with Ca EDTA, ear provocative rritarion fails. A four- to aii-waub trout ment-fraa parted abouid ba allowed to atapaa bafora evilaatisf a provocative study. Bafora chain/ I would Uka to aa/ a word la dafanaa af tba treatment of laud poiaoulas with Ca EDTA. Wa ha* baau utfardad tba epporluait/ to aupanriaa tba truatroaut of aiaa cuaao of iaorgaale hud polaeulag In adulta urttb wbat wa prurioual/ assumed warn permanent aeuraiug leal chaa/ea, aad bora aaae miraculous roomlaa aftor treatment with Ca EDTA- Oaa of tbaaa caaaa bad fonuna aitanaor wrokneaa. vrristdrop aad other asuruio/ical dlaturbaarua far to /aara whlla raaaaialac out of txpoouru with out imprvraUMut: aad aftor aaa aad a balf /aur* of intermittent Ca EDTA tmtmeot ba racararod normal function Tbla aua waa briaa ra tirad aa total!/ disabled, auppoaadl/ urttb CHS hwe. at tba time wa ftrat aaw him. but waa re turned to aonaal work aftar bla traatnaat uritb Ca EDTA. Ha bad uararofnlaad complicated bad poteculag. aot CHS syphilis. Wa boro aaau aurora rolic rallavad b/ Ca EDTA when calcium (taroaala, morphtea. Danarot and Dllattdld bara (traa no ruilef of pal*. Wa Kara aaaa a raaa of byperchronlr anemia, fatlgua, waaknaaa and vague Joint palna from had re spond wttkla da/a aftar Ca EDTA tbarapr, /at tba pal lent had format!/ failed to respond. aftar retsoral from ix pea u re to load for about a /ear and Irmtmaal b/ eeverel nrallaut Inlaruleta wltb Hear. Eu and Iron. Aftar a abort parted of dull/ Intravenous treatment, tbla raaa waa Utar /lean oral Ca KDTA b/ hit ph/alclaa, and Immediate!/ developed a ana plua albumlnurta whlcb tbarad aftar four mootba. HU kidnap function atudiaa abowud aa abaoraallt/. HU own ph/aletaa U rarlala that tba temporary albuDilnorta waa from ora) Ca EDTA. Other than that ooa tnatanca of lanporar/ albuminuria that deralopad aftor oral Ca EDTA, wa bara aot aaaa an/ adewraa vffect from two- to alfhl-waak Interm11trot treatment with four or ftru dull/ letravrooua t gm doeea. aor froea tba aporadU atperlmental oaa of daO/ t gm oral Ca EDTA. Wa bare /iron several hundred troatmrola with Ca EDTA aiacu IMS. Scant Individuals ia aur group. wttb aauroputblaa, baau baau treated iatermlttaut!/ for aa hue *e two /aura. wa. waiTtaa: Could 1 aak /eu. worn all tbaa* man boepiteilned. ar ana working? BE atu.: All tba man wttb aauroputblm. ex cept one. ware boapiUUaad darts/ Ihtir ori/taal atad/ aad trautmast. After partial racorary the/ war* followed oa the job, and hnepl tell aad oat/ Intermittently avary mouth or alx weebe for arraral da/a of treatment aad stud/. citaihMAM aownrica: I think tbh bring* aa to tba aad. Wu hero alroady bad tba dlecuaatea af the ftaal papar. tba aaa bp Dr. Kahoa, aad a> that It left b Dr. Shipman's mmmaiUa. Dose aa/nau wtab to auataeurUa tba sammatUw? me warns*: I deal waat to iiMmnln tba aummallou, but than an some tblapa 1 would Ilka to aak. 1 am a h/iaaa aad aot a doctor, although t ban baau doeeiy amarlatad with hod-eupoaad persona far about S3 yuan. Back la IMS, a rommitteo uf tba atoed nputaUe mm is Ibuir Said la tba United Status pabtlehad a marvelous booh railed "Occupational Lead Expouuru aad Laad Potecmlag." 1 doel know wbata tba raspoealbilit/ lias for fettle/ out a aaw aad revised udltioa of thh autborttotln boefclat. but until standardiaod tocbalfuua aad w--L totioea an sat up. wu an fuiap to caatlaaa to ban dicerea opiatuaa and dhrurua papers. I hope that acana da/ tba Laad ladrotrias Aaaoclatloa will tab# H upoa ttestf to publUh a booklet by tba exports aa that athsn who an ant aa wad loformid may readily refer to expert dla/aoetic matkeda af avalaatiap had absorption and tba various accepted tacksi/sm for datarmlalap had la air, hud la blood, had la urine, porphyria velum, aad aa aa. But to educate tba satin world, af toorust h a Mg order for the laud Industry. caaixMAM anwofTTM: Than la aa each thing a* getting all tba doctors to egne aa than chan c m. It cast ba done. la than earthing further? ME w a l t x x j ; Work towards that aad. **. tai/MAM: If aa me aha imarlw tba summary, porheiu for tba aak# af the record I would Ilka to da It mycolf; and perhaps aattripata tba IMP maottng. Tbara an aartotuly areas af Imenace la tba ftaM af lead taut- ROUND TABL* T coloyy, Bod tt MM to *a* tbat tb* |>I whUh w *10 br brarln* about In yr*r* free* amr will lerolrr a ceetlmuttoa at tb# *to*r*J rtudle* oa Irod pbyaiolofy and load toxkolocy, tudlrr tuch a* UkM dcwcribod by Ana* B*rtjr and Bob Kabo* tod*/- Wi certainly would kof>* that tan year* from now w* wtB bar* non prrda* laboratory tost* far exact drtrrmioatlo* of tb* 4*fr* of load poiaonin*. and certainly w* bar* rraaoa to bop* that, ton pan fruca new, w* will know nor* about tb* btotoflcal, offsets of unaB doM of bad. Tb* fact that xporr*a and blood sod arln* Iml* ar* kapt b*tow a ewtate point Io n not ywaraatr* tbat daaaaf* iaa*l botaf don*, damac* wblcb w* ar* tUS onahlo to dotamln*. Now tbia I* not aaythlnf dlrortod only at land Tb* aam* thin* la tru* la a wid* variety of Mda- Aa 1 aald at luneb. tb* Ideal expoaoro la arm Bocnrwber* brtwMB aaro aad wbat wo Bl*bt call premia*Ibl* Irrtla, tbrr* la aa ana wblcb mjulrr* atady, aad t -ould bop* tbat tbia will b* a topic oa tb* a*rod* (a Iftt. cnaaaiN aowwTC*: 1 drclar* tb* eoafomaeo a> oa rod, aad I tbaak yo afl for aaald** M neb ronrrr* ''r-L ' V^'r . V:- ; ' ;"V- '' e'fac > hifmhaa'Vi^i' 'rrlh^GM&l i 'i'i n mi\ i/ihiiiliri< re ;:1 ATTENDANCE at LEAD HYOtENI CONFttENCI NtvMtW 6*7, IfU V E. L Notional S*Jtty CmL Chicago. A J. C AiA. MX), Mutw^MtA Gwwtl tiitw. Mm. *Am M. ScD. Joke* Keplifli Sch, Hyg. I FA. HwlA, liMniri, ML P. J. Umbry^, MX). lothlakam Steel Company, IttMohim. Pa. A 6. lettte, >. M O, Cleveland CUc. Cleveland. ON# *. L lehnep, MX), Mergvette (Wnnity Sckeel af Medicine. MFwliM, Wk. L L lehnep, >a MX), MkwkM, Wiiciw'a It F. M. MX). Colorado Urvvertity School el Markka, Doovor. Cole. Oaa lehreel Ratal Paint 4 Welpeper Dietribytett el America, S*. lawk, Me. 0. M Imw. lead Indyetriee Aaaooetioa. Nan Yai H. Y. t>(a<>M la-ditch. teed Maltiw Alicciriioa. Naa Yarh, N, Y. Mn. MauM IniMi, Naa Tat N. Y. S. H. layer. MX). loda*. MtawimWl F. F. ley* MA), US-S. lead ReWy, lac, Eod CNcaaa. M A E. Iratfay. MA), The Uamerdtv Haapital leMmer*. Mi. C. 0. lodge*. Indaatrial Medvd Aaiilriia*. Chlcana, & Marie lajy. MA. Ui. Steal Capariiia. Plttibyrgh. Pa. 0. H. lyan. US. PybCc HaaM> Service. Ockneti Okie *A K. Ivan. MO. CMdroa'a Moditd Canter, loeton. Maw. A C. CaMra. MX), MMiitl la-Il UkaMain. lac, MirikWaaL, H. K M Caaa. MX), US. Pybtc HaaMi Servian. Woafcingtoa. a C. A P. Carrel. MX), Ckicege. Saak V. A Codrop. Generd Matao Corporation. DeteaM. Mid* A A Ovenlm. Jr, MO, Jehae HepUnt School a( Markka. leKmerg. MA Jeaeph Ondin, MX), tarda IWanly SMdi *f Sckaal al Medicine. Clime K G. 0. Garten, American Mnlrial Hyaena AatciaHaa, Detroit, Midi. G. H. CaXrat, Jr, M.0, Craaa Company. Chico g a. A N. A Colombo. MX), Hodton, MiaailaH Fred Coat litvmlnovi Catwhy Company. tact Mead, I. A. G. Creech, MX), Calaeaia Corporation of America. Ne Yart, N. Y. M F. Oat*. Jr, MreJecVey CkomkH* Aaeacletion. Wellington. D. C. IMa Drlnier. Sc-0, Harvard School al PvMc Health. laden, Maw. 1. H. Dnyed. M O. Arm Chom't al Center. Maryland Ed-erd Uda, PKO, S--m and Company, Chicago, A A F. tea. Jr, A/genne National laboratory, Oeonert Grove. A *K A lhie*. PWD, Moiiochviotta Orrldoa Occvpetiend Hygiene, laden. Mate Tharaaa Faaalar. Netiend Safety CoyneI. Chicago. A Harry Foremen, MO, U. al CaMarraa SciaetrFc laboralary, lat Alamat. Nrv Mac. J. H. FoUger, MX), L. L da Pant da Naaaal I Compear. Wlmlngton. M l W. Ftadu Farra Corporation. CleveUed. Okia A G. Fraiiar, M.0, Amoricon Academy at Pediatric* |vaartan. A W. G. Fradrich, ScO. Oatrait Oapartamet al HaeHk, Datralt, Mich. H. G. Gardmr, M.0, Inland Steal Cempenr. tad Ckicaaa. lad. I. A GaM-atar, MX), Catymbia Unrryrvty Ichaal al Pybka Health, Naa Yarh. A Y. A. W. Gardan, Implayart Mv*val liabAty Iravranca Campaay, Ckicaga. A Mr*. A. W. Gardan. CMcaga. Beah L I. Cardan. Zyr*k lnyran<# Campaay. CMuya, A Sam Got* HaUam PradvcH Campany. Cbkaaa. A A M Grakom, M O, The Peftne Campany. tlilia* A P. 0 Haley, Standard Ol Company. Ckirefa. A *U I. Hambn, M.0, American Gala |ia Company, Ckkaga, A J. W, Hemmand, Hymk4 04 I laTmUn Company, Havdan, Tat. tHarriat L Hardy, M.D, Maaaackvaattt Ganard Haapital laden, Mae* V.^rf-'* ^ 'y^ r i. r- 5. - L Km. &r ATYKSIMWE G. C. Hartald, MiG, Indintrie! Health. Hygiene I Safety Sendee, Royal Oak. MIA. W. G. Haiard. Owena-U.neit Cfeta Company, Toledo, Obi# *W. C. L Hameon, H*mtii Au mU^h , fithW^li, Pa. N, V. Htndricki. (m Rwa(A 4 i^WiAa Company, LMm, H. X *C. H. Hina, MO. California Uiwmili Mrd.cel Center, San Frenciece, CtBf. X 0. Holland. MG, American Mednel Aiaociation. Chicago, IX X C. Ho^nbW. M.0, Indwitriel Med*cel Aaaociafion, CAiufa, A, J. X HcJ*away, American Rrtle Shoe Company, Chicago, KL X O. Jeckton, Engineering Deedepmed Company, CoraepaBl, fa D. R. Johna, MG, fi< Chicago, Indiana A. S. Johnton. American Meted LiabXtr Inaerence Company, V> ekafieU, Matt. I. T. Johnatone. MG, lot Angdae.'Cehfcmae f. T. jwAa MG, America" Medical AMMation Oikaya, ML I A. Kehoe. M O, U. ol Cncmali KaMarinp laboralary, QndnaP, Ohio I. E. KwcMa, Employer* MAal UaUity tnamanca Company, Waaaaa, Wk Mra. I. 1. Kvechie, Wavtaa. Wncoetin It. Cel F. W, tenerd, MC. Amy Chemical Center. Maryland Pad Lanya, Employer* MHd LiabXry Inaaraaca Canyany, Mlriilaa, Wk. A. X lanaa. MG, Nt Ycrl City, Naa York *0. X Lavar, MG, Janaa t laada Stad Company, PitHborgh, Pa *0. P. liipama, MG, Delta, lanaa W. W. MaAlty. MG, Occupational Hyyana t Medical Servient, CTereland. Ohio May R. Mayan, MG, Non Yard Oty. Harr York X r. McCehen. MG, WaaHm Bettric Company, Chicago, IX C- P. McCord. MG, MicMyan Urveervty School of P*bfic Health, Ana Arbor, Mkk W. L McCormick X f. Goodrich Company, Akron, OUa W. T. McCormick Inland Slant Cempty, tail Chicago. lad. *L C. McGee, MG, Haredot Pander Company. Inc, WRmJngtoa. Dal Mr*. L C. McGaa, WJnvngton, Delaware T. L McGrow. MG. Bectr* S<oraoa Rettery Company, Phlodtlphla. Pa , W, G. Maada. Hartford Accidant I Indemnity Company, CMcaya, X - ' L H. MA>. M.0. U. at Ocmneti Kettering laboratory. Cincinnati, Ohio S. X M*er, MO. Michigan Udeervty Imtrfvte of Indwcfriet Health. Am Arber. Mich. K. M. Mona, US. Sled Corporation, Prttabvrgh, Pa Jda Mranam. National load Company. Omega. BL *P. F, Murphy. Hammond load hadrch. Me. Hammond, InX *C A. Nee. MG. Unrrervty of leant, GeHeaten, Tea. *K. W, Neleen. American Smelting I Refining Company, Sail Lola Ofy, Utah X L Nana. MG, FOilman Kodak Company. Rocha alar, N. Y. X F. OToelo. Chicago, IK-aod *W. M. PaCtt, Electric Storage Rattary Company. Philadelphia. Pa H. 0. Pocock Jr. MG. Bactric Storage lattary Company, Oevelerd, Ohio J. C. RadchRa. Fard Molar Company. Dearborn, Mich. L N. Retermene, National load Company, Granite City, ML X I. Ream. MG. Standard Of Company. Chicago, fll fad RaanAoR, MG. Carnal Uwaniti Madtal Calaga, New York, H. Y. P. S, Richarda, MG. Mamarlal Mad<al Cantor, Salt Lola City, Utah A. II Riddtl, MX. Taranto Oapartmant of Health, Toronto, Canada Daniel Ring. Noliand Paint. Varmah t leaguer Aaaaciatian, Waihingtan, D. CL C. X Ragara. Hammond Load Predvctt. Inc. Hammond, InX N, J. Raaa. MG. Ilmen Oapartmant of Public Health, Springfield, M. O. A. Sander, MG, Mlweaken. Wlacanaia *H, N. Sanford, M.D, Chicago. Bmaia XW. A. Sawyer. M O, Intarnatmnaf Attaalallan of Mechinhft, Rachaafor, N. Y. L L. Sthal. New Jarlay Department of Health, Trenton, N. Robert Schindler. GUI* Union. Inc. MJwevVte, Wk. H. H. Schrank. Ph 0, Indwttrid Hygiene Fovndelien. Prttabvrgh, Pa T. 1. Sh.pmen, M 0 . U. el Celitormo S<mnt.fi laberalery, Lot Alemet, New Mae, J, I. Skinner, American Matvei LakJiiy Interance Company, WakefieiX Mata. H. D. Sm.rh, MG, The Chadron'a Hetprtel Cwiainnati, Ohio *1. W. Spelyar, M.D, Inddna State ton'd el Health, Indienapet*, laX J. J. S*aper, M.D, Cennactnvt Oapartmant d Health, Herttard. Conn. H H. Sternberg, M 0. Chitaga. tt-noh *H. I. Stokrngar. Ph 0. U.S. Pwbhe Health Sarelca. Cincinnati. Ohio Acttrt Partwpanti I s s ; It ATTENDANCE J. A. Ttytor, Met ><y BWm, Atlvttt, M. H*l# Vn*fv U.D, Nititul ImJ C HwyMy, CKlffi. I, f* A. V## Attt, fki)^ OtlrtA, MidtlfM L X Wd. M.O, Eua Su~4^i Ol Ca-*#*y, N# Y#r< N. r. CtH NeKenti LeeA Ca-ip#y. Ckicaya, . H. T. WeNrortV, Lumbermte'i Mvtwel C#i#>ty Ctwptay. CVItl #. , f. L Wm#r, U-S.S. Ld Rf.n#ey, lc. Et CUt#a, Ud. *T. C. Wttefi, M2#4 #d Stsckbrido#, i#Xi--ipr#, Md. Oottct W#b#r, TKe Iwnkte HE Ctuttwy, K4yt. Wtfct K X Wtkei, Atwiut FtiJry*t'i Vpcirty, 0#t rl#ia, . 6. Wt WkeatWy, Mi, MttitftlHtt LX# lnwtMt Ctnytty, Nw Y#L H. Y. P. H. WVHiW, Mi, AlitCUMn Hxtttriwhg Cvwty, MIwUw, Wk. W. C. WI#Mt, M.D, Nttaml Utl Cttftty, hrfb Aty, H. X Mu W. C. WJttli, F#rrii Aly, Nt# Jpn#y H^*ict* Win, MLO.. laXa-oe# City H##Mh Piitmal. Wiwi MX G. M. WEniny, (m MmM Ol Ctnytty, Nw TL N. Y. L a Wfcoa. PM). WU. W##M1 Hyf.x ##rt. Mktreterta#. CVinaa, a W. G. Waad. VU>, twj L**d cjytmv, Graaita Oy, a Mn. W. G. Wool. Grwdta Of. Kaak *f, L W#rme, l*#d Gdtrit Aitaci#ti#a A St. Jwiyt U#l Ct, Nr Y#r4, H Y. T. ML Walk, H#*aa M C##ftty, Ne# Yart. N. Y. W. P. Y#at, ScD. Mi-# S#t#ty Aff*-cat CMfw, PittXar-fc. Pa. *1 L #ft#U. Ih I Ud#trit A - triitic-, Nn Tara, N. Y, Aettr# Prtieiftalt : > l