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M0NS 0 9 7 4 7 8 TOXICOLOGY A APPLIED PHAA4ACOLOGY to MAY 3 1974 VahwR, Ma 2, Unary OH CONTINTS ALAirw V. Nm, Unl E- MAwnam-Tmiw, ANTNONr It- Piu-- ako Maajpwm A. FmcMr*. Feeding Umdn on Lx--cil wUkKUbJ Dog.................... US IbanrR Br_mjs urn Cwwi V. Fonn,Ji. Iurfcliuw of >i*)*myopiiwfii widi Ckforal HytnmmdTiirhlwnhrlRhnmNir............................................................................... 223 Kcrni H. ImomN, Rartuao Y. Y ami Lnun A. Forts. TRs Hwofrlk Activity ofSome Tririkyltm md Triphmyhin Gompmmfe........................................................................... funoMi R. Snmll amp Waiiam A. Otow. Tbs lUKliMlMOy of Owfcwlw WiOiMd by VXmiStripm Mm............................................................................ OaunN. Nkmbl NM^MirM D^MMion of Lymphocjp Onialb. ............................... 2)0 Ml 253 Itetr W. Fumtmmam, IAjuth Iquitm, taw A. Hcyman, Riomo S. Nun, Haim ItapKiAiwiANPVwaiMliBMi fMcMwcM TomsMapc BwOtfap qf<CbWMQwaxhi A3 (NQC-50 314) m Mm, Pop md Mihgp. ................................................................ 2)0 M. J. NimsiM L H. Nn Triannc Ams-termA, ML Smootm. Tbs Okk otTam Horn (Oiripi lipmd Rl C31........................................ 271 Rawalp E. Muut and Jam E. 0pm. ftayM DmMm ip RM. (Mm Pip iM Mgafcpys. ............ 2tt T. H. Gmki and E. C Fouudb. Aom 0m ofCMmm a Ptmhmt TaMw fmeticm m Robbiti.............................................................................................................................. 2f2 Mvpom A. Mcmmam, Uuiam Ym amp Rkhasb CJMMJiPliMiRAMHRj*"*'**"1*' __ J.E.Gray.ItN Weavik,1.h "" ` J, A. Botumr. J. E. Gray, J. P.^hwPTTgTS^J^MoKA^. Wm*m. Mmapo D. GoLacnaN and0PCAA J. Balcdum. Maditotiap of* RmpompofRMSto uihpl Lodi cfOwn by EnqK-fiMWR| A|Mi.................................................................... y. UnuT.M.CAtxtJM AMOM. Adolphs. EllectonwiprswiwRMCMtMPd R*t Hmrt CcMs. Baml K. J. Uom0<TmovmvO. T. Ts'q amp Mavmapo R. OsMOwini TttttaAf Atrophy from IwbslMiM of BbyitPi OM Cyclic Totromcr ................................................................ * Raul M. Hrh amd Rknaro A. Buxmmld. Ammonis Dmowfybn Mrtinimi at RamhppTVoM Alfod by Dirtier njpMrip. .................................................................... RmapoA-Ham AbsorpM. DmrRiMimi mti EmMou at Iworpnir Tm m Rits.............. H. M. Mauno* B. Hicmmam, M. A. Wiuaaad, W. Saul, W. M. kmp, J*. amp R. B. I _ RcdHOtai by Nmimp with Otbmmmm at HMMaMdty brim* by Cvbop Tm TMmwmM m DMRp4MwM..................;........................................ D. Kapapkum,G. Bmdand E. Bmndmotm. PnDJaOumd f |.HiiiijiOilwrH<Q<irtwlMOlMwiiMairTMi rw amm*............. .............. M. Q. JOWMA AMP W. C ULam. BhM of > 322 330 330 342 IS) m m YMctwr N. ntPMi. ROMO M. Bum, Raspscu H. Mowtaoup *m Hapolo 0. NPM MvSp MWMM pri>*ptap: IIMI MsiR FmstiaM at Tat 4i$ Mr ntfo M. Jn tua amp Jaaps I. .Vraumn. Tbc rjinpriwip Efcl gfTtfctMpMMcMM m ihc Rat a* l-raMmcd by the Mjcrowdnu Tol ................................................................ EumWnriLK. Jaaps J.Kotmam -------- -----------r*-'Tr-l nflWri iw~Tl Iwimimi itp wto CirraMtinf trttwocylc*. ............................................................. ^ gjj ^j| ?rr."t**?** , lM W. SM^as^TT if It mswyriilfin m Octautal j, Mia .......... 4* M f.-..,, ...-------- -.r^.---------- .. *** !**<H--fcua*--m ............................................. <34 TOXICOLOGY & APPLIED PHARMACOLOGY ^ ^ 1974 HONS 0 9 7 4 7 9 rim CONTENTS M. F. Ctwi LAM) AMT M. F. Comma. EHocta ofo^ -OOT cm the Admml GM and Hepatic MATiwnul Fv>-w S>M the BaaJtOei ............................................................... I J.K. PkiiKmiu. B. TMiMnwKA,]. M. WMmK**KNrrt.MW. aouMMU. Maovy Btfeline in*bcKidneyaadt.iwrofRaitBcpcaicdhrCRpoaadlnMcnTic Chioride: Induonon of Meiiliuhimein by Mercury and Cadmium ....... .............................................. It T. Hath AM)S. Kjtauawa. Bbdiofi New ^TriaHuTiTima'ilrtr t'-l IHn Mm--id Ral tonnes........................................................................................................................ 20 D. J. EnwMiwm amt A. M. Clmtau. Genetic Polymorphum of form Ciitoybiwiiri m hc Rahhit: CondMioo with Ptwrmacoingic ml Tonkolooic Dferti ............................... 21 ifmmv H. Twnnw. Chc Su, Jcan C. Sluh, Dewrau Auao Lmue Cum. Tmion Anna, Wuaian S. Uokota. Maocia Simon. ano Douglas Silva. Efltett of Chronic Nicotine AdmmitfflMKM ti Ayr on Varioua NanoCnmotiMm and Aaaocmaad Enqno io Male Fncher-.H4 Ram ......................................................................................... 41 F. Ixtrson. R. H. Dowktc. H. L Twenholm. and C. Paul, `immrfatinn and name Oitiribuiion of Mercury in the Cieam during Subacute AdatiMaumioa of Mnhyi Mercury. 40 RiTHAan Lacomk ano Juus Buorm*. The ERact at formamaal mdf Omldrm an Camera A i no Parameters of Enzyme Induction in Mica.................. ............................................ 20 Mkiiatl P. Octu. Plasma Eazyaae AoMtiae in Coiantia QoaEPad Gmdad Oeaaa of DOC, WyeWnimaf Biphenyl, MahMluua and Maronric Cltorida .......................................... 04 CHamoPHca M. PacoHuraA BoaaaT E. UaaoK. am Coy Mmmt, Efltt of Clnoaic DOT Eaposwc on ftmobartncal Tnlaraooa and lain*aai'i ia dwRai...................................... 99 Feapeame M. Raozialowbu AwnJama A. Ornmiiiiai, Mbcfrfybmmydidmc on Hepatic Drug Metabolism m tlm Rat .............................................................................................. 101 Ladrso W. Ncuon ano William A. Ksllv. Chaapn inCiaiat Miaunaiy Gland lUmoicij durino the Eairom Cycfc..................................................... 113 BfRXAOixi Manttlajl-Plata and Ravmomb D. HABanoK. Made of fomtortital nd SKF 323A Pireiaaamal.8aa.Lwnr Ipjary. and Vtiiirlron^*-TmaiiyilmrianahiftnlToxicity.. 123 Gamy E. tew am Jam L. Wav. Ahatcliart of m Kb* Ghana MaiahnMin by Cobahoua Chloride...,....................................................................................................................... 131 Juur L. Ebmar. hear J. Comma, andJamb E. Cmaan. Kbmtfccofm Vbrm Niro Reduction naTlrTrtTnmnpniin................................................................. 140 J. E. Gray, R. N. Wcavol, A. A. Soocula. P. E. Jemma. mb J Mopaii. Finn Indamd FmriBoady Chamali lid hy Lipid m Mamaph^m........................................................ 149 Yubal K. Limuu and HAaam RoatuCTAwir CmaNaiO: Nmmirhamiral Ammaa *ar Oral Chmam AWamiatmtioa in Raaa........................................................ Aujn Yabooky. MamP. nanaaor. Huon ^mr Pin-iit--iamp. i^rEwnil Gurnm. An It Menu Study at da taaailaiaps and Mpi Bhco of ilyeandiDna hi .Trdfmam me n--aMuAeaad --d NonmAaacd Miaa.......................................................... ICO Riuaaf T. IOi am* JamR. Fouil The Laci of Effectsof Pictraatomat aid Phaooharbital and itthwirnum^ne on dm Acute Tonicity of Banaene in Rao...............w Dayht T. Omtil TmwAi L Run a. an Faaml L. Craco. Elm of Lon RanAm FooW on lmJineihacm4ndoccd Intestinal Leatoaa in Rats............................................................... Shout CiumuKiTAnnm ____ __ . ----------- StrntrN T. Kru.f>. Frbjoutk W. Omo. and Shoyll & Homon. EEact of Chronm Diettry Nitrami on Canine Thyroid Fanctaan............................................... .............." Tarki Yamamoto. Maia^cmmi YAUAGUon. a Yawncmu Swccta. Calcwm Acoamidtion in Lhor and Cataum MobiBraiion in Bona of Lead Pamnnad Ram.......................... Roaear E. Mancpo ano Jamb J. Kocam DaiitihifciddiBida laaaaam Ida UChaMty ofCO. in Rata but Pceraaaeaha llumminairiy .......................................................................... Alnlcd H. Mcuull ano T. Coun Curnu Piiliniiiary Smdy of N PWo ASMoain li Mnabaliam by Hunmo ...................................................................................................... * ISO