Document QX9YJMNkvzgGbrQRGRgq9kN24

too Mtrtb U46r|li Hvd. St, loit 66, Minot CHEMICAL SPECIALTIES DATA REPORT Th Inlormothm In thin rtfl wm rompilod to nwilnt you In your ovoluotkm anH rfovolopmml ot itporlal unm for Monruinto product*. Kvory fforl Hon boon modo lo Indudo ptrlinenl malerial boOrinc on th mibjort. Thlo information la inland, no. cs-6 fiJOTE to outdo your davoiopmant work, but Monaanto cannot taka part in tha nportAc formulation or evaluation ot any Aniabed knowiodffa of such should ba raaarvad lo iftan your meat valuable trada aarrot. Mm Datk March, 1961 U<ul Ao>c/or 4i > irt-t&vf) sLtyJtfJ A. c*jetz. - MONSANTO AROCLOR* RESINS FOR INSECTICIDE FORMULATION! A Discovery A simple method of Increasing the service life of expensive lindane sprays was developed several years ago by U. S. Depart ment of Agriculture scientists at their Beltsvllle, Maryland, testing station. The technique was to Incorporate Monsanto's "Aroclor" 5460, a resinous chlorinated terphenyl in the lindane solution. This pale yellow solid reduces volatility of the' lindane -- slows it down to an effective, but not wasteful, evaporation rate. The result is an insecticide deposit on treated surfaces that lasts up to ten times longer than that left by straight lindane solutions. Normally, simple solutions of lindane leave a crystalline residue that dissipates within a few weeks. On hard surfaces such as glass, metal or painted areas, the residues last only about a week. Because lindane is a well established and effec tive pesticide, U.s.D.A. researchers sought a way to Improve the lasting qualities of lindane residues. Of numerous com pounds tested, "Aroclor" 5460 gave the best results at lowest cost. Test Work A major objective of these studies was to develop a suitable formulation for application to crops and other plants. Al though results under carefully controlled conditions were quite promising, subsequent tests by other agricultural ex perimenters gave only moderate success. Consequently, Interest has been slow to develop In agricultural circles. Apparently, the vagaries of sunlight, weather, and plant growth represent too many variables for effective study of the formu lation residues by direct application to exposed plants. * Aroclor: Reg. U. 3. Pat. Off. 055558i \_ Tbo Intermatioii In tkia buMatin bs to wr boat bnawliJpi, ImasnO aowntatian wtlb tiw urn t Him date ar wagmtima. mw, (to --wm-- W (to an tom, to tototo. Tto Wtounl. Ctomtol Oftfmt totolmi w feMMr toNto, to ' -aw ( ' ' SSmSShi* or lUnmT*1* * adtT TOWOLDMONOQ43671 A Mew Idea But another possibility for putting the U.S.D.A. discovery to work has lain dormant until recently} thin la the possibility of using to good advantage the ability of "Aroolor" realna to make the lindane adhere to smooth hard surfaoea like metal, glass, painted areas, eto. This would oonslst of painting or spraying "Aroolor"/llndane formulations on suoh areas as the Inside of garbage can lids, on window screens, doorallls, the painted walls of outbuildings, dairy plants, storage areas, eto.. In order to obtain lasting control of flies, ants, roaohes, sUverflsh and other troublesome pests. Suitable formulations oan be readily paokaged In shoe-polish type "dauber" bottles, aerosol spray cans, and bulk packages for meohanloal spray application. Development of this Idea is based on the following! Advantages of UBlng "Aroolor" Resins In Insecticide Formulations A suitable "Aroclor" (Monsanto makes Bevan) can romarkably extehd the effective life of lindane and other ohlorinated lnseotloldes as much as ten times (up to 2 and 3 months). "Aroclor" reBlns are very low In cost (around 20^/lb.). Small quantities are sufficient (5 to 25 parts per hundred, by weight). Formulation Is extremely simple -- the resin la dissolved In a suitable solvent compatible with the Insecticide. stable In Inventory and In lnseotlolde formulation. "Aroclor" reBlns are fire-resistant, non-oxldlsable, non-oorroslve, withstand weather extremely well. Non-staining "Aroolor"/lnsectlolde films formed when the solutions dry are praotloally Invisible. "Aroolor" 5460 has a pale yellow color as supplied. Other suitable "Aroclor" products are nearly oolorlesu. , "Aroclor" resins are odorless -- won't Impart "ohemloal" odors. "Aroolor" resins are safe to handle as long as they are not volatilised and Inhaled. They are praotloally non-volatile at ordinary temperatures, do not Irritate or aenaltlae normal skin. The nature of the residue oan be varied. Monsanto supplies a variety of "Aroolor" resins. These are ohlorinated to various degrees and vary in physloal properties as follows! Monsanto Ohemloal Specialties Data Report CS-6, ....page 2 o'.***8* TOWOLDMON0043672 Chlorinated Terphenyla Aroolor 5460 - Yellow, transparent, friable solid (dries hard) Aroolor 5442 - Yellow, transparent, stloky seml-solld (dries tacky)! Aroolor 4465 - Yellow, transparent, brittle resin (dries stloky) Chlorinated Biphenyls Aroolor 1262 - Light yellow, atloky, viscous semi-solid (dries stlc| Aroolor 1260 - Pale yellow, soft, stloky aeml-aolld (dries Btlcky) Aroolor 1254 - Pale yellow, viscous oil (drlea "wet") Experimental Work and Formulations I The following Information was derived from preliminary reports on work done by U.S.D.A. research groups. These data are not to be oonstrued as recommendations by either the U.S.D.A. or Monsanto, but rather are Intended to serve as a guide or starting point for the development of private formulations. Fifty to 200 milligrams of lindane per square foot of surface has given good Insect control on nonporous surfaces. The ratio of lindane to "Aroolor" 5460 has been varied from lil to 1:4. For most purposes a 1:1 or a 1:2 mixture la satisfactory. Formulations aB used In the U.S.D.A. experiments are: 1) For application as a solution. Lindane "Aroolor" 5460 Carbon Tetrachloride 5 parts by weight 5 parts by weight 750 parts by weight (Carbon tetrachloride Is toxic and should be handled with extreme caution. Lena toxic solvents are easily obtained.) 2) For application aa an emulsion. , Lindane "Aroolor" 5460 Xylene "Triton" X-100 (available from Rohm ft Haas) 20 parts by weight 20 parts by weight 100 parts by weight 3 parts by weight To obtain a stable 1 lindane emulsion, mix 1 part by weight of the above oonoentrate to 13 parts by weight of water. Monsanto Chemical Speolaltles Data Report CS-6, .Page 3 05555B3 TOWOLDMON0043673 3) For ue an a pressurized (aerosol type) spray. a) Lindane "Aroolor" 5460 Methylene chloride "Freon" 12 (DuPont) 5 parto by weight 5 parla by weight 40 parts by weight 50 parts by weight b) Lindane "Aroclor" 5460 Cyclohexanone Ortho-dlchlorobenzene "Freon" 12 (DuPortt) 5 parts by weight 5 parts by weight 10 parts by weight by weight by weight Experimental Results - American Roaches Using Formula 3a or 3b, the toxloant was applied onto a painted wall, depositing about 200 mg./sq. ft. of lindane and a like amount of "Aroolor" 5460. When the toxloant coat was one month old. It gave 90-100$ kill of Amerloan roaches when the roaoher oontalned In a petrl dish were placed against the surfaoe of the treated wall for two hours. The U.S.D.A. research team found that the lindane-"Aroclor" 5460 mixture (used at the rate or 50 mg. of actual lindane per sq. ft.) would kill 80$ of all cockroaches exposed for 2 hours to a oO-dayold treated surface. It remained lethal to 66$ of the roaohes after 90 days. Regular lindane sprays used at the same rats killed only 4$ of the roaohes after 60 days. Results with Housefllea Deposits of 25 mg. of lindane plus 25 mg. of "Aroolor" 5460 applied from carbon tetraohlorlde onto glass and aluminum (hard surfaces) gave 100$ kill of normal houseflies exposed for 2 hours to these treated surfaces after they had aged 18 weeks, the duration of the test. Without the "Aroolor" the hard surfaoes treated with lindane alone ware effective only about a week. A lindane plus "Aroolor" mixture sprayed as an aerosol onto leaves of a willow tree continued to kill houseflies after 2 months of outdoor weathering. Careful Inspection of the treated leaves showed that the toxloant was held firmly to the surfaoe and notwithstanding rain and weather, the coating re mained In good condition. Also, within limits of a preliminary Inspection there Beemed to be no Injury to the willow leaves. Monsanto Chemical Specialties Data Report CS-6, ......... Page 4 0555584 TOWOLDMON0043674 Al o 0555584 01 TOWOLDMONOQ43675 (Note; The primary purpose of thin report is to provide In formation for the development, of suitable Insecticide formula tions for application to "nonconoj.live" surfaces such as metals, glass, paints, and other materials that will not be damaged by the application. Development of formulations for living plants requires sufficient teat work to Insure that the formulations will not be Injurious to the plants or their products.) Another Formulation Reported A more recent development In these experiments Is the following simple formulation; "Aroclor" 5A60 2556 Lindane 2556 Methylethyl Ketone (MEK) 50J5 Work on this was reported In the August l'l, 1951* Issue of Chemical Week magazine. ThlB simple formulation appears to be most suitable for "painted on" formulations packaged in bottles but should be used with caution In mechanical spray equipment since the MEK solvent will soften rubber and certain plastics. The formulation oould also be modified easily for aerosol packaging. Since MEK evaporates rapidly, It should not seriously affeot painted aruae unless too heavy applications are made. The package label should Include a caution to thla effect. AIbo, MEK Is flammable. Possible substitutes that are leas flammable are methylohloroform or a mixture of mothylc.hloroform and methylene ohlorlde. Formulating Other Insecticides The beneficial effects of "Aroolor" &460 apply generally to 1 other chlorinated Insecticides Including ohlordane, aldrln and dleldrln, but do not apply to phosphate type Insecticides suoh as TEPP, parathlcn, methylparathlon, malathlon and chlorothlon. , **** For samples of the "Arcelor" products mentioned In thla report, contact the nearest branch offloe (see attached Hat) or write to; MONSANTO CHEMICAL COMPANY Organic Chemicals Division Plasticizers Department 800 North Lindbergh Boulevard St. Louis 66, Missouri Monsanto Chemical Specialties Data Report CS-6, ....Page 5 TOWOLDMON0043676 / MONSANTO CHEMICAL COMPANY organic Chemloala Division District sales Offloes ATLANTA! 1401 Peachtree St. N.E., Atlanta 5, Oeorgla BOSTONi Everett Station, Boston 49, Massachusetts CHICAOOi McOraw-Hlll Building, 520 N. Michigan Ave., Chloago 11, 111 CINCINNATIi 2330 Vlotory Parkway, Cincinnati 6, Ohio CLEVELAND! 427 Hanna Building, Cleveland 15, Ohio DETROIT! 10230 Orand Hlver Avenue, Detroit 23, Miohigan HOUSTON! 2472 Bolsover St., P. 0. Box 6863, Houston, Texas LOS ANQELESi MINNEAPOLIS! 6670 E. Flotilla St., Los Angeles 22, California Foshay Tower, Room 515, Minneapolis 2, Minnesota NEW YORK! 445 Park Avenue, New York 22, New Ypric PITTSBURGH! 20 Cedar Boulevard, Pittsburgh 28, Pennsylvania SAN FRANCISCO! Ill Sutter Street, San Francisco 4, California SEATTLE! 911 Western Avenue, Seattle 4, Washington SYRACUSE! 731 James Street, Syraouse 3, New York WILMINOTONi 2Q05 Conoord Pike, Fairfax, Wilmington 3, Delawaro LONDON! Monsanto House, 10-18 Vlotorla St., London S.W. 1, England MELBOURNE! 256 Flinders 3treet, Adelaide, Australia MONTREAL! P. 0. Box 900, Montreal 3, Canada TORONTO 183 Front St. East, Toronto 2, Ont., Canada VANCOUVER! 1550 Rand Avenue, Vancouver 14, B. C., Canada 0555586 TOWOLDMONOQ43677