Document QX33XmRKw7B4Q3B1kXoZwzky8

CORNELL UNIVERSITY MEDICAL COLLEGE 1300 Yo r k Av e n u e Ne w Yo r k 21. N. Y. July 22, 1946. Dr. Robert A. Kehoe University of Cincinnati College of Medicine Eden Avenue Cincinnati 19, Ohio Dear Dr. Kehoe: The points raised in your letter of July16th touch upon aspects of editorial policy which are certain ly important. I take it that you feel that Dr. Deichmann's paper ought to be published even if it contains only con firmatory data. To this I am inclined to agree, especially in regard to information relating to a compound of such practical importance as DDT. The best outlet for such papers is another question. As you know it is the policy of The Journal of Pharmacology and Experimental Therapeutics to devote space only to original observations of pharmacologic interest. These may concern new drugs, mechanisms of action, or thera peutic effects, but should represent some advance in the field of pharmacology. As I remember Dr. Deichmann's paper it does con tain some new points of pharmacologic interest, but since some of these were side issues as you indicate they might need to be more fully documented before publication. Tox icity data and evidence bearing on the mode of action, if confirmatory of other work, would need to be presented very briefly or perhaps given only passing mention. I agree that evidence bearing on the toxicity of DDT is of great interest at the present time, but confirma tory work of this nature might be more appropriately published in other journals more concerned with practical applications such as the Journal of Industrial Hygiene and Toxicology. We have the same problem in connection with work done in this laboratory. I suppose that during the past two years experi- r DEPARTMENT OF PHARMACOLOGY CORNELL UNIVERSITY MEDICAL COLLEGE 1300 YORK AVENUE Ne w Yo r k 21, N. Y. Dr. Robert A. Kehoe -2- July 22, 194b meats on toxicity and mode of action of DOT have utilized more than a thousand cats, but the work falls so closely in line with re stilts already reported that I doubt if we shall submit it for publication. The work was none the less worthwhile since it served a purpose when informa tion was needed by the armed forces and is doubtless now reflected in present civilian applications. In conclusion let me say that I hope that Dr. Deichmann's work will be published. I believe that it records facts which could form the basis of a paper1 for The Journal of Pharmacology and Experimental Therapeutics perhaps with some additional evidence along the lines sug gested by Dr. Wallace. Sincerely yours, 'll O1) 'v l X- `--v . McKeen Cattell K 0020134