Document QMMzJ3kxYoj2BJmwN8jd7pqMk

Page 1 of 5 1 NLM CIT. ID: 98060531 TITLE: Occupational exposure to polyvinyl chloride as a risk factor for testicular cancer evaluated in a case-control study. AUTHOR: Hardell L; Fredrikson M; Ohlson CG ADDRESS: Department of Oncology, Orebro Medical Center, Sweden, lennart.hardeIl@orebroll.se PUBLICATION TYPES: JOURNAL ARTICLE LANGUAGE: Eng REGISTRY NUMBERS: 0 (Plastics) 9002-86-2 (Polyvinyl Chloride) ABSTRACT: Occupational exposures were assessed in a case-control study on testicular cancer using self-administered questionnaires. In total, answers were obtained for 148 (91%) cases and 315 (87%) controls. Of the cases, 101 had seminoma and 47 had embryonal testicular cancer. An increased odds ratio (OR) was found for exposure to polyvinyl chloride (PVC) yielding an OR of 6.6 (95% confidence interval, 1.4-32). The risk increased further if cases with self-reported cryptorchidism or orchitis were excluded. Six of the 7 exposed cases had seminoma. Exposure to other types of plastics did not significantly increase the risk of testicular cancer. MAIN MESH HEADINGS: Testicular Neoplasms/*CHEMICALLY INDUCED/COMPLICATIONS Polyvinyl Chloride/`ADVERSE EFFECTS Occupational Exposure/`ADVERSE EFFECTS ADDITIONAL MESH SUBJECTS: Support, Non-U.S. Gov't Seminoma/CHEMICALLY INDUCED Risk Factors P1astics/ADVERSE EFFECTS Orchitis/COMPLICATIONS Odds Ratio Neoplasms, Germ Cell and Embrycnal/CHEMICALLY INDUCED Middle Age Male Human Cryptorchidism/COMPLICATIONS Case-Control Studies Aged Adult SOURCE: Int J Cancer 1997 Dec 10;73 ; 6 : : 2 NLM CIT. ID: 97268353 TITLE: Parental occupational exposure ar.o me risk of testicular cancer in Ontario. AUTHOR: Knight JA; Marrett LD ADDRESS: Division of Preventive Oncology, Ontario Cancer Treatment and Research Foundation, Toronto, Canada. PUBLICATION TYPES: JOURNAL ARTICLE LANGUAGE: Eng ABSTRACT: The incidence of germ cell testicular cancer is increasing, but its etiology remains largely unknown, initiation may occur in a parental germ cell. In a case-control study in Ontario, jobs and industries of mothers (before and during pregnancy) and fathers http://igm-U7.nlm.mh.gov/cgi-bin/iyi4d_U.igm BFG 00267 BFG40773 i/dU/yx