Document QJ37911qLRxLmX1EBmda7r2OL

4 V xxxmxxxaac t C'` C>; .(fczlth Services and Mental Health Adcinistmtion ' - Rooa 403, Federal Gffico Bids. 5X0 Main Street National Institute for. Occspatienr.l Safety and Health September 9, 1071 ^33 Dr.' Lee Grant Pittsburgh Plate Glass Co. One Gateway Conte? Pittsburgh, Pennsylvania 25222 ii r~ - Dear Dr. Grant: Referring to cur conversation on Tuesday concerning tl:c eencentrctiontis-es-tine relationship of asbestos dust exposure to clinical changes, I uou2d like to quote froa a recent publication of the National Air Pollution Control Administration,* which states: "Asboetccis usually develops after leaf exyiesnre to high concentrations ef dust. Tao risk varies directly Kith the length of exposure and dust concentration, renewing continued closure to high concentrations of dust, asbestosis VzY develop fully in 7 to 3 years s*.:d nay cause death as early as 13 years froa r.nsct of exposum." Ocher articles that shew this concentra tion- tin-ca-tino relationship ai*c as follows: 1. Lenta, A. J., McCohr.sll, U. S., and Fchnel, J,: Effects of the luhr.lotion of Asbestos Dust on the Lungs of Asbestos Workers. Jhiblic Health Reports, 30, 1215, 1. - w pi * '* -- -- ^ | - w* p p*p-w i Department, Public Health Service, Washington, D. C., 19*50. 3, Gsanslor, Edward A., and Eaplan, Alfred I.: Asbestos Pleural Effusion. Annals cf Internal Medicine, Yol. 14, Wo. 2, Pod., 1971. 4, Ihr.t, Foss: Routine Lung Function Studies cn S39 Employees in Asbestos Preceasing factory. Annals of the Hsu* York Acadecy t of Sciences, Vol. 132, Art 1, Pago 405, 1955. 5, i 11 Less, hr-gcr and liugh-Joucs, r.: The Significance of les:tj Faction Changes in Asbestosis, Thorax, Vol. 15, 103, 1960. 6, Sslikoff, I. J. and J. Ckttrg, end 2. C. !Learor.d, Tko Occurrence of Ashes teris Axsn* Insulation r.Vrkevc in the United States, /um. W. Y. Acad. Gei. 152: 139 (1965). __________ | BB 00 22537 [ THIS DOCUMENT WAS NOT A RECORD OF PPG INDUSTRIES, INC. DID NOT COME FROM IT'S FILES AND CANNOT BE AUTHENTICATED BY PPG INDUSTRIES, INC. \A C e> 5439 # Page 2 ~ Dr. tee `Great ^ * -.v-5' - . Dust concentrations ia these articles represent similar concentrations to those found in the Port Allegany plant by the United States Tublis Ijsalth Service. Ax yea can cad will see these articles indicate that the clinical changes, which occur with enposxires of less than seven years duration are consistent with Asbestosis. If you havo any other questions concerning this relationship please feel free to contact no. aTM #* * Sincerely yours, * Richard A. tenor* Senior Addistant Sanitarian .Division of Clinical Investigations end Field Studies Sullivan, Ralph J. and Athanssslndis, Yanis C.: Prclininnry Air Pollution f:a*vt*y of Ash ostax - A tit erasure Review. Kational Air Pollution Central h adaistrnticn Publication Ko. AT7D G3-27, October, 1DGD - cc: t!r. David L. tayliss - Dr. willisa Johnson Dr. Joseph Wagoner NOTF HOT Cia-- I Wi< I 1 < * J I BB 0022538 J ' this document was not a record of IT'S fTfU-m!ES' INC' D1D N0T CPME FR0M- 5440 V