Document OV8bLxMNyM3ygNJ8jXVzb63K
Monsanto
from (name * location) Dept, of Medicine & Environmental Health " Judy 2ack-A2SA
DATE: SUBJECT ;
September 19, 1978 Krummrich PCB Study
CC: F. C. Meyer-A2SA
REFERENCE:
TO File
Work sheets attached.
mo Att
Judyw Zack
i
IN-IOM was
/
DSW 153368
STLCOPCB4040438
CAUSE OF DEATH CLASSIFICATION
Cause of Death
Malignant Neoplasms
Buccal Cavity and Pharynx
Digestive Organs
Liver
All Other Digestive Organs (Residual)
Respiratory System
Lung
.
All Other Respiratory Organs (Residual)
Genito-urinary Organs
Lymphatic and Hematopoietic Tissues
Leukemia and Aleukemia
. Other and Unspecified Sites
Diseases of Cardiovascular System Diseases of Respiratory System Diseases of Digestive System All Other Diseases (Residual) External Causes of Death
All Causes
U.S.D.R. Program Category Numbers
1
140 150, 151, 153, 154, 155, 157 155 150, 151, 153, 154, 157 160 162 .160 minus 162 177, 178, 180, 181 200, 205 204
1 minus (140, 150, 151, 153, 154, 155, 177, 178, 180, 181, 200, 204, 205) 339, 340 470 530 0 minus (1, 339, 400, 470, 530, 800) 800
157,
160,
0
DSW 153369
STLCOPCB4040439
KRUMMRICH PCB STUDY: OBSERVED AMD EXPECTED DEATHS, ALL MALES
Cause of Death
Observed
Malignant Neoplasms Buccal Cavity and Pharynx Digestive Organs Liver All Other Digestive Organs (Residual)
Respiratory System Lung All Other Respiratory Organs (Residual)
Genito-urinary Organs Lymphatic and Hematopoietic Tissues Leukemia and Aleukemia Other and Unspecified Sites
(Residual) Diseases of Cardiovascular System Diseases of Respiratory System Diseases of Digestive System All Other Diseases (Residual) External Causes of Death
8 0 1 0
1 4 4 0
1 1 0
1 14
0 2 3 1
All Causes
28
Expected
3.875 0.144 1.126 0.0 81
1.047 1.296 1.207
0.089 0.423 0.173 0.133
0.538 10.223
1.087 1.118 2.256 2.330
20.889
SMR
206 0 89 0
96 309 331
0 236 578
0
173 137
0 179 133
43
134
Bionomial
.032 . 866 .689 .922
.718 .039 .031
.915 . 347 .159 . 875
.442 .101 .330 . 30 8 .395 .311
DSW 153370
STLCOPCB4040440
KRUMMRICH PC3 STUDY: OBSERVED AND EXPECTED DEATHS, WHITE MALES
Cause of Death
Malignant Neoplasms Buccal Cavity and Pharynx Digestive Organs Liver All Other Digestive Organs (Residual) Respiratory System Lung All Other Respiratory Organs (Residual) Genito-urinary Organs Lymphatic and Hematopoietic Tissues Leukemia and Aleukemia Other and Unspecified Sites (Residual)
Diseases of Cardiovascular System Diseases of Respiratory System Diseases of Digestive System All Other Diseases (Residual) External Causes of Death
Observed
4 0 0 0
0 3 3
0 0 0 0
1 10
0 1 2 0
All Causes
17
Expected
2.418 0.0 89 0.648 0.041
0.608 0.829 0.775
0.054 0.238 0.117 0.098
0.398 6.324 0.626 0.729 1.066 1.451
12.614
SMR
165 0 0 0
0 362 387
0 0 0 0
251 158
0 137 188
0
135
Bionomic
.215 .915 .517 .960
.538 .04 7 .040
.947 . 787 .889 .906
.332 .058 .528 .525 .289 .219
DSW 153371
STLCOPCB4040441
KRUMMRICH PCB STUDY: OBSERVED AND EXPECTED DEATHS, NON-WHITE MALES
Cause of Death
Malignant Neoplasms Buccal Cavity and Pharynx Digestive Organs and Peritoneum Liver All Other Digestive Organs (Residual) Respiratory System Lung All Other Respiratory Organs (Residual) Genito-urinary Organs Lymphatic and Hematopoietic Tissues Leukemia and Aleukemia Other and Unspecified Sites (Residual)
Diseases of Cardiovascular System Diseases of Respiratory System Diseases of Digestive System All Other Diseases (Residual) External Causes of Death
All Causes
Observed
4 0 1 0
1 1 1
0 1 1 0
0 4 0 1 1 1
11
Expected
1.457 0.055 0.478 0.040
0.439 0.467 0.432
0.035 0.185 0.056 0.035
0.180 3.899 0.461 0. 389 1.190 0.879
SMR
275 0
209 0
228 214 231
0 541 1786
0
0 103
0 257
84 114
8.275
133
Bionomial
.047 .946 . 387 .961
.361 . 379 . 356
.966 .170 .055 .966
.834 .587 .624 .327 .663 .600
DSW 153372
STLCOPCB4040442
RATIOS OF ST. CLAIR COUNTY TO U.S. CANCER MORTALITY RATES, WHITE MALES, 1950-1969
Cause of Death
Malignant Neoplasms Buccal Cavity and Pharynx Digestive Organs Liver All Other Digestive Organs Respiratory System Lung All Other Respiratory organs Genito-urinary Organs Lymphatic and Hematopoietic Tissues Leukemia and Aleukemia Other and Unspecified Sites
St. Clair County Rate*
196.0 8.1
64.0 4.9
59.1 53.6 49.7
3.9 29.4
7.9 9.8 11.1
U.S. Rate
174.04 5.36
58.30 5-16
53.14 40.95 37.98
2.97 29.31
8.94 8.81 10. 73
Adiustment
1.13 1.51 1.10 0.95 1.11 1. 31 1.31 1.31 1.00 0.88 1.11 1.03
Rate per 100,000 population.
DSW 153373
STLCOPCB4040443
RATIOS OF ST. CLAIR COUNTY TO U.S. CANCER MORTALITY RATES, NON-WHITE MAj.ES,. 1950-1969
Cause of Death
Malignant Neoplasms Buccal Cavity and Pharynx Digestive Organs Liver All Other Digestive Organs Respiratory System Lung All Other Respiratory Organs Genito-urrnary Organs Lymphatic and Hematopoietic Tissues Leukemia and Aleukemia Other and Unspecified Sites
St. Clair County Rate*
185.8 5.4
74.3 8.1
66.2 42.4 38.2
4.2 30.9
5.6 6.7 4.4
U.S. Rate
184.28 5.42
68.30 6.91
61.39 39.94 36.67
3.27 35.41
7.73 5.77 6.48
Adjustment
1.01 1.00 1.09 1.17 1.08 1.06 1.04 1.28 0.87 0.72 1.16 0.68
*Rate per 100,000 population.
DS\N 153374
STLCOPCB4040444
KRPMMRICH PCB STUDY: OBSERVED AND EXPECTED CANCER DEATHS (ALL MALES) BASED ON ST. CLAIR COUNTY ADJUSTMENT*
Cause of Death
Malignant Neoplasms Buccal Cavity and Pharynx Digestive Organs Liver All Other Digestive Organs (Residual) Respiratory System Lung All Other Respiratory Organs (Residual) Genito-Urinary Organs Lymphatic and Hematopoietic Tissues Leukemia and Aleukemia Other and Unspecified Sites (Residual)
Observed
8 0 1 0 1 4 4 0 1 1 0 1
Expected
4.204 0.189 1.234 0.086 1.149 1.581 1.464 0.116 0.473 0.157 0.127 0.422
SMR
190 0
81 0
87 253 273
0 211 637
0 237
Binomia
.049 .82 7 .649 .917 .680 .071 .056 .890 .379 .146 .880 .346
Expected number of deaths multiplied by ratio of St. Clair County to U.S. Cancer Mortal.
DSW 153375
STLCOPCB4040445
KRUMMRICH PCB STUDY: OBSERVED AND EXPECTED CANCER DEATHS (WHITE MALES>BASED ON ST. CLAIR COUNTY ADJUSTMENT*
Cause of Death
Observed
Malignant Neoplasms Buccal Cavity and Pharynx Digestive Organs Liver
All Other Digestive Organs (Residual) Respiratory System
Lung
All Other Respiratory Organs (Residual) Genito-Urinary Organs Lymphatic and Hematopoietic Tissues Leukemia and Aleukemia Other and Unspecified Sites (Residual)
4 0 0 0
0 3 3 0 0 0 0 1
Expected
2.732 0.134 0.713 0.039 0.675 1.086 1.015 0.071 0.312 0.117 0.086 0.410
SMR
146 0 0 0 0
2 76 296
0 0 0 0 244
Binomial "p'
.287 .874 .483 .962 .502 .091 .077 .931 .730 .889 .917 .340
*Expected number of deaths multiplied by ratio of St. Clair County to U.S. Cancer Mortality
DSW 153376
STLCOPCB4040446
KRUMMRICH PCB STUDY: OBSERVED AND EXPECTED CANCER DEATHS (NON-WHITE"MAIZES) BASED ON ST- CLAIR COUNTY ADJUSTMENT*
Cause of Death
Observed
Malignant Neoplasms Buccal Cavity and Pharynx Digestive Organs Liver All Other Digestive Organs (Residual) Respiratory System Lung All Other Respiratory Organs (Residual) Genito-urinary Organs
Lymphatic and Hematopoietic Tissues Leukemia and Aleukemia Other and Unspecified Sites
4 0 1 0 1 1 1 0 1 1 0 0
Expected
1.472 0.055 0.521 0.047 0.474 0.495 0.449 0.045 0.161 0.040 0.041 0.012
SMR
272 0
192 0
211 202 223
0 621 2500
0 0
Bionomie
.049 .946 .414 .954 . 384 .397 .368 .956 .150 .039 .960 .988
Expected number of deaths multiplied by ratio of St- Clair County to U.S. Cancer Mortality Rate
DSW 153377
STLCOPCB4040447