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GENERAL OFFICES 2501 HUDSON ROAD ST. PAUL 1.- MINNESOTA TEL: 733-1110 M ED I CAL D EPA R T M EN T - I N D U S T R I A L HYGI ENE . CENTRAL RESEARCH D EPA RT M EN T PLEASE REPLY TO j 2301 H U D S O N ROA D ST. PA U L 19. M I N N ES O T A October 1, 1963 Robert A. Kehoe, M.D. Kettering LaboratoryCollege of Medicine University of Cincinnati Eden and Bethesda Avenues Cincinnati 19, Ohio Dear Dr. Kehoe: We have a research program in one of our laboratories involving the use of tetraphenyl lead and triphenyl lead chloride. At present there does not appear to be any health hazard involved since we are able to work with small quantities using good exhaust ventilation. However, as our experimental program grows there will be larger quantities in volved, more people involved, and a greater opportunity for exposure of individuals. It would be greatly appreciated if you could give us some information on the toxicology of these materials along with any special recommendations you might have for determining atmospheric concentrations and for monitoring the health of these research people. We have been unable to locate any literature relevant to this class of compounds other than the sort which you have contributed to regarding tetraethyl and tetramethyl lead. Thank you very much for ary help you can give us. Best regards. RCWtamn Industrial Eygienist N7942