Document OJKGd2Od5dDXzk18xR66n9861

U/ t v T xL-ilf^vmJ), C-. - -1 - < * o ' MEDICAL CONTROL OP OCCUPATIONAL LEAD EXPOSURE Pre-employment examination Complete throughout Careful history Previous occupations Present subjective picture by systems Careful physical examination Special attention (1) Gastro-enterie tract (2) Vascular system ' (3) Neuro-muscular Laboratory procedures Special attention to Blood Hemoglobin Differential leucocyte count Stippling Clinical urinalysis Lead analyses when previous exposure in doubt 0008739 _? _ Purposes Base line record Suiting workmari to job Elimination of definitely unfit Persons seriously exposed recently Persons with vascular disease Persons with hepatic disease Persons.with gastro-enteric sluggishness Periodic Re-examination - periodicity determined by conditions Interval History Importance of subjective symptoms Careful physical examination Unhurried . Repetition of laboratory study Blood - Stippling - hemoglobin Urine - Clinical examination Analytical examination if possible Necessary if exposure dangerous The importance of good records Medical data for study - medico-legal consideraticn Examination when required by Illness History important in relation to physicians knowledge of plant Necessity of arrlving#at a diagnosis, not merely convicting or excluding occupational factors KF 0008740 i 3- - difficulties develop. Diagnostic Criteria in Relation to Lead Intoxication Lead Absorption Stippling of Erythrocytes Mean 53918 per million erythrocytes Upper limit not far from 1000 - hraigrehepr erson Quantitative.information necessary Stippling and lead exposure abrupt changes significant Stippling and other factors Seasonal Anemia , Other Lead Line Differentiation Bi smuth Natural pigmentation Increased lead excretion KE 0008741 Lead Poisoning Actual illness characterized by (1) Gastro-enteric symptoms (2) Neuromuscular disturbance (3) Cerebral involvement Associated with blood change (If no stippling, no intoxication) Sequellae Neuro-muscular Cerebral Hematopoetic ? ANEXPERIMENTAL STUDY OP LEAD ABSORPTION The normal Intake and output of lead Lead intake and output under conditions of experimentally induced lead exposure Immediate response to increased intake Relation to industrial lead exposure Eventual response to increased intake Threshold of Intoxication not reached. < AInbtnooxrmicaaltiaobns.orption and excretion without Correspondence of blood and urinary levels to those seen In occupational lead exposure Comparison with results at H.R. plant.