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jniversity of Cincinnati Medical Canter institute of Environmental Health Kettering Laboratory 3223 Eden Avenue C.ncmnat'. Chio -526" 3>,one 513 372-57Q0 Apri16,1982 Mr. Seymour G. Epstein Technical Director, Safety & Health The Aluminum Association, Inc. 318 Connecticut Avenue, N.W. Washington, Q.C. 20006 Dear Mr. Epstein, We have just received a microfiche which may be of interest to you and your associates. I am enclosing the bibliographic information and table of contents for the Proceedings of the National Workshop on Substitutes for Asbestos held in Arlington, Va., on July 14-16, 1980. Could you please advise which sections are of interest to you? We can, of course, provide copies from the microfiche, if you wish. The first quarterly report on health effects of aluminum compounds in mammals, 1982, was mailed to you yesterday afternoon. Thank you for sending the criticisms of the 1980 and 1981 reports. We are getting to work on them immediately. Sincerely yours GLK/1# enclosure Geraldine L. Krueger Senior Research Associate Bibliographic Research Oivision Patient Care Education * Research Community Service 003753 TX T1NER RMC00065Q7 BIBLIOGRAPHIC INFORMATION PB 81--1 76778 Proceedings of the National Workshop on Substitutes for Asbestos Held at Arlington, VA.f on July 14-16, I960, Nov 80 Arlene Levin. PERFORMER: Env irormental Protection Agency, Washington, DC. Office of Pesticides and Toxic Substances. EPA-560/3-30-001 SPONSOR: Consumer Product Safety Commission, Washington, Sponsored in part by Consumer Product Safety Coaalssion, Washington, DC., and Interagency Regulatory Liaison Group, Washington, DC. The purpose of the National Workshop on Substitutes for Asbestos was to obtain aore information on the technical and econoalc feasibility and possible health problems of substitutes for asbestos, f*r use In considering regulation of asbestos. Soae of the topics discussed include: Non-asbestos friction materials; Discussion on friction.' products; Gaskets and packings; Asbestos in plastics; Discussion on plastics and flooring; Single-ply roofing as s substitute for asbcs.es roofing felt; Mill applied coatings for underground plpe'i**s; Discussion on pipeline wrap; Discussion on tcxtll>, Asbestos substitutes la roof costings, sealants, sd cements; Substitutes for asbestos-cement sheet; Inhalation, deposition, and clearance of particles; Man-man vitreous fibers and health; Discussion on the translocation, and fate of sited man-made mineral fibers; Exposures to mineral wool; Toxicology, aspects......... KEYWORDS: 9Asbestos, 9Meetlngs, `Synthetic fibers, 9Glass fibers, 9Carbon fibers, `Ceramic fibers, 9Fibcrs, `Industrial hygiene, 90eeupatlonal safety and health* Available from the National Technical Information Service, Springfield, Va* 22161 PI ICE CODE: PC A99/W A01 003154 TXTJNER RMC0006508 CONTESTS Acknovlsdaaate vlil Introductory Raasrks, Richard J. Cuiaond 1 Overview of Regulator? Status, Peter Prsuse cad Warrsn Muir 3 ECONCHIC SESSIONS: Richard J. Culsond, Chairman WORE SESSION ON FRICTION PRODUCTS Non-Asbestos Friction Materials, Michael C. Jacko, Charles M. Sruahofsr, and F. Vlllisa Aldrich Diacuaaioa on Friction Products WORK SESSION ON GASXZTS AND PACKINGS Gasket* and Packings, Stephan 0. Koehler OiacussiOQ on Gaskets and Packings WORK SESSION ON PLASTICS AND FLOORING Asbestos in Plastics: Looking for Alttrnatlves, Matthew Naltova Dlscussloa on Plastics sod Flooring WORK SESSION ON PAPER AND ROOFING PRODUCTS Single-Ply Roofing as s Substitute for Asbestos Roofing Felt, David E. Bailia Roofing Felt, Nancy Ro/ Discussion on Roofing Products Mill Applied Costings for Underground Pipelines, Jeck Vink Discussion on Pipeline Wrap WORK SESSION ON TEXTILES Textiles, Sanuel G. Menfer Discussion on Textiles VOCR SXSSIGtf ON SRAUWZS Asbestos Substitutes In Roof Costings, KennethSrsosowskl Orerrlsv of Asbestos Substitutes in Sealants, Roof Coatings, and resents, trie Votnser Discussion on Ssslsats WORK SESSION ON SUBSTITUTES FOR ASSZSTOS-CZMCrr SHEET Gloss Fiber Reinforced Canent, John Jones and Frank V. Feksts Other Substitutes for Asbestos Cssent Sheet,DavidCoglsy Discussion on Substitutes for Asbestoe-CenestSheet 9 32 35 58 59 69 71 75 82 84 99 101 106 109 113 U9 121 129 135 precedes P38 W* 003755 TX TINER RMC0006509 VOW SESSION ON SUBSTITUTES FOR ASBESTOS-CD<ENr PIPE Substitutes for Asbescos-Ceoenc Pipe, Richard A. Simonds and Jama* t. Warden Dlseuaalon on Substitutes for Aabestes-Cemeot Pipe 139 161 PANEL ON DEVELOPMENT OF SUBSTITUTES Presentations by Richard J. Cuiaond, Robert Moore, John Gurtowskl, Roy Stelnforth, James T. Reis, and Barry Cattleman 163 Dlseuaalon on Development of Substitutes 175 ROUNDTABLE DISCUSSION SESSIONS Introductory Material 'o Roundtable Dlseuaalon Sessions Stomerle* of Roundtable Discussions PRODUCT AND SUBSTITUTE MATERIAL REVIEW SESSION 181 194 229 HEALTH SESSIONS: Janes N. Rowe, Ph.D., Chairman Scope of the Health Workshop, Janes N. Rowe OVERVIEW OF THE ROUTES OF EXPOSURE Inhalation, Deposition, and Clearance of Particles, Morton Llppmann Fate of Ingested Particulates, Janes Killatte znd M. Eosenthal Diseussloo on the Routes of Exposure SYNTHETIC FIBROUS SUBSTITUTES Man-Man Vitreous Fibers and Health, Jon L. Xonsen Discussion on Man-Made Vitreous Fibers The Translocation and Fats of Sized Man-Made Mineral Fibers Following Exposure by Intratracheal Instillation In Rats, David M. Bernstein, Robert T. Drew, and Marvin Kuechnsr Discussion on ths Translocation and Fats of Sized Man-Made Mineral fibers Occupational Exposures to Mineral Wool, Douglas F. Fowler Discussion on Mineral Wool Mortality Patterns of Rock sad Slag Mineral Wool Production Workers, Cynthia F. Robinson, Gregory 0, Ness, Richard J. Waiveller, sad John M Penan c Discussion on Rock and Slag Mlaoral Wool # Industrial Hygiene sad Toxicology Aspects of 3M Hextel 312 Ceramic Fibers, Robert S. Larsen end Wllllan McCormick Discussion on Cerasic Fibers Toxicology of Aranld ribers, C. F. Reinhardt Discussion on Arsnld Fibers Environmental Exposure Considerations Dus to the Release of Graphite Fibers During Aircraft Fires, Benjia Suseholx Discussion on Graphite Fibers 279 283 313 323 329 342 343 391 399 418 419 420 425 441 443 448 451 474 003756 vi TX TINER RMCQQ0651Q NATURAL FIBROUS SUBSTITVTES Cro*s-Sectional Medical Study of Wollaseonice Worker*, Brian Boehlecke, 0. M. Shaeby, M. R. Petersen, T. 1C, Hodoua, aud J. A. Merchant DlscuJ*ion on Wollaatonite Eidetic Pleural Disease la Relation to Zeolite Exposure, Arthur 8. Rohl Discussion oo Zeolites in Turkey CheaXcal Detoxification of Asbestos Fibers, Earl S. Flowers Discussion on Cheaical Detoxification of Asbestos Fibers 475 476 477 482 489 497 XATUlAL NON-FIBROUS SUBSTITUTES Health Considerations la the Perlite Zadueery, W. Clark Cooper Discueston oa Perlite Review of the Health Effects ofHicas, liner Lusts Discussion on Mies Health Effect* of Vernlcullte, Janes E, Lockey end Stuart M. Brooks Discussion on Vernlcullte 305 311 313 354 355 560 Talc: Roundtable Discussion (Evening Session) Opening Remark*: Natural Non-Fibrous Substitutes: Talc, Arthur M. Laager 563 Cross-Sectional Epidenlologic tad Industrial Hygiene Survey of Talc Workers Mining Ore from Montana, Texas, sad North Carolina, John Gamble, Alice Creife, aad John Hancock 570 RounH cable Discussion on Talc 812 SYNTHETIC HOtf-FIBROUS SUBSTITUTES Occupational Exposures in ehe Manufacture sad Appllcstlon of /olyurethaae aad Urea Formaldehyde Insulation Systos* Robert f Herrick, A. A* Alcareee, R. ?. Reiedorf, end D. U. Rtsuey Olacuseloa oo fossa Htsaa Pulnooery Function Study (5 years) on Oceupstlonal Isocyeaats Exposure, Haas tfeill Discussion on Isocyanate 621 644 647 652 CRITERIA FOR EVALUATING SUBSTITUTES Criteria for Animal, Tissue Culture, and Biochemical Studies on Asbestos* Mineral Dusts, aad Proposed Substitutes for Aabestoe* Earl S, flowers 653 vii 003757 TX TIMER RMC00065I1 University of Cincinnati Medical Center Institute of Environmental Health Kettering Laboratory 3223 Eden Avenue C.ncmnati. Ohio a257 =Kone 513 872-3700 April 6, 1982 Mr. Seymour G. Epstein Technical (Director, Safety & Health The Aluminum Association, Inc. 318 Connecticut Avenue, N.W. Washington, D.C. 20006 Dear Mr. Epstein, We have just received a microfiche which may be of interest to you and your associates. I am enclosing the bibliographic information and table of contents for the Proceedings of the National Workshop on Substitutes for Asbestos held in Arlington, 7a., on July 14-16, 1980. Could you please advise which sections are of interest to you? We can, of course, provide copies from the microfiche, if you wish. The first quarterly report on health effects of aluminum compounds in mammals, 1982, was mailed to you yesterday afternoon. Thank you for sending the criticisms of the 1980 and 1981 reports. We are getting to work on them immediately. Sincerely yours GLK/1# enclosure Geraldine L. Krueger Senior Research Associate Bibliographic Research Division Patient Care Education Research Community Service 003758 TXTINER RMC0006512 BIBLIOGRAPHIC INFORMATION PBB1 -176778 Proceedings of the National Workshop on Substitutes for Asbestos Held at Arlington, VA., on July 14-16, i960, Hov 80 Arlert Levin. PERFORMER: Environcental Protection Agency, Washington, DC. Office of Pesticides and Toxic Substances. EPA-560/3-80-001 SPONSOR: Corstaaer Product Safety Consission, Washington, Sponsored in part by Consuser Product Safety Coecission, Washington, DC., and Interagency Regulatory Liaison Group, Washington, DC. The purpose of the National Workshop on Substitutes for Asoestcs was to obtain sore inforaatlon on the technical and econoaic feasibility and possible health probleas of substitutes for asbestos, for use in considering regulation of asbestos. Soae of the topics discussed Include: Non*asbestos friction aaterials; Discussion on friction.' products; Gaskets and packings; Asbestos in plastics; Discussion on plastics and flooring; Single-ply roofing as a substitute for asbos'.os roofing felt; Mill applied coatings for underground pipe*1*os; Discussion on pipeline wrap; Discussion on testll>, Asbestos substitutes la roof coatings, sealants* a*d assents; Substitutes for asbestos-cssent sheet; Inhalation, deposition, and clearance of particles; Ksn*an vitreous fibers and health; Discussion on the translocation and fate of slsed nan-cade cineral fibers; Exposures to slneral wool; Toxicology, aspects, .... KEYWORDS: 9Asbestos, 9Meetlngs, ^Synthetic fibers, 9Glass fibers, 9Carbon fibers, 9Cersslc fibers, 9flbers, Industrial hygiene, 90ecupatlonal safety and health* Available fro the National Technical Inforaatlon Service, Springfield, Vs. 22161 PRICE CODE: PC A99/Hf A01 003759 TX TIMER V RMC0Q06513 s CONTEXTS AckaovltdpMnt* vlii Introductory Renerks, Richerd J. Guiaond 1 Overview of Regulatory Status, Peter Preuee cod Verren Muir 3 ECONOMIC SESSIONS: Richard J. Culaond, Chairaan WORE SESSION ON FRICTION PRODUCTS Non-Aabeetoe friction Materials, Micheel C. Jccko, Charles M. Brunhofer, cod f. Wllliaa Aldrich Discussion oo friction Products WORK SESSION ON CASKETS AND PACKINGS Gcekcee cod Peeking*, Stephen D. Koehler DUcueeion on Ceckets end Pecking* WORK SESSION ON PLASTICS AM) FLOORING Asbestos in Plenties: Looking for Altemetlvee, Matthew Neltove Dlecuesloo oo fleetlc* ead flooring WORK SESSION ON PAPER AM) ROOFING PRODUCTS Single-Ply Roofing ee e Substitute for Abo*to* Roofing felt* Devld E. Belli* Roofing felt, Nancy to/ DUcueeion on Roofing Produce* Hill Applied Coating* for Underground Pipeline*. Jack Vink Discussion on Pipeline Vrap VORX SESSION ON TEXTILES Textiles, Seauel C. Meafer Discus*ion on Textiles WORE SESSION ON SEALANTS Asbestos Substitutes in Roof Costings, KennethBrsosowskl Overview of Asbestos Substitute* in Sealants, Roof Costings, sad Cenents, trie Vornser Discussion on Seslsats WORE SESSION ON SUBSTITUTES FOR ASBESTOS-CEMENT SHEET CUss fiber Reinforced Ceneat, John Jones sad Prank V. Pekets Other Substitutes for Asbeetoe-Ceneat Sheet,DevldCogley Discussion on Substltuteo for Asbostos-CensatSheet 9 32 35 58 59 89 71 75 82 84 99 101 106 109 113 119 121 129 135 precedng page blank 003760 txtiner RMC00065U Js~ ^*'7-& - WORK SESSION ON SUBSTITUTES FOR AS8ESTOS-CTCNT PIPE Substitutes for Asbestos-Cement Pipe, Richard A. Slsonds end James L Warden Discuasioo on Substitutes for Asbestca-Cement Pipe 139 161 PANEL ON DEVELOPMENT OF SUBSTITUTES Presentations by Richard J. Cuiaond, Robert Moore, John Gurtowski, Roy Stelnforth, Janes F. Reis, and Barry Cattleman 163 Dlseuaslon on Development of Substitutes 173 ROUNDTABLE DISCUSSION SESSIONS Introductory Material ro Roundtable Dlscuaalon Sessions Sunarles of Roundtable Dlacusaiona PROOUCT AND SUBSTITUTE MATERIAL REVIEW SESSION 181 194 229 HEALTH SESSIONS: James N. Rowe, Ph.D., Chairman Scope of the Health Workshop, James N. Rowe OVERVIEW OF THE ROUTES OF EXPOSURE Inhalation, Deposition, and Clearance of Particles, Morton Lippnann Face of Ingested Particulates, James Millette and M. Rosenthal Discussion on tha Routaa of Exposure SYNTHETIC FIBROUS SUBSTITUTES Man-Man Vitreous Fibers and Health, Jon L, Konsen Discussion on Man-Made Vitreous Fibers The Translocation and Fata of Slxed Man-Made Mineral Fibers Following Exposure by Intratracheal Instillation la Rata, David K* Barnataln, Robert T. Drew, and Marvin Kuschner Discussion on the Translocation and Fata of Sistd Man-Heda Mineral Fibers Occupational Exposures to Mlnaral Wool, Douglas P, Fowltr Dlscuaalon on Mineral Wool Mortality Patterns of Rock and Slag Mlnaral Wool Production Verkara, Cynthia F Robinson, Cragory 0, Naas, Richard J. Vaxwellar, and Join M. Dement Discussion on Rock and Slag Mlnaral Wool # Industrial Hygiene sad toxicology Aspects of 91 Hoxtal 312 Ceramic Fibers, Robert 5. Larsen and William McCormick Discussion on Ceramic Fibers Toxicology of Aramld Fibers, C. F. Reinhardt Dlseuaslon on Aramld Fibers Environmental Exposure Considerations Due to the Release of Graphite Fibers During Aircraft Fires, Benjamin Susshols Discussion on Craphlte Fibers 279 283 313 323 329 362 363 391 393 618 419 620 623 661 663 448 631 676 003761 TXTINER yi RMC0006515 NATURAL FIBROUS SUBSTITUTES Crote-Sectional Medical Study of Wollastonite Worker*. Brian Boehltcke, 0. M. Shaaby, M. R. Petersen, T. K. Hodoua, aud J A. Merchant Discussion on Wollastonite Endemic Pleural Disease in Relation to Zeolite Exposure, Arthur 9. tnhl Discussion on Zeolites in Turkey Choice I Detoxification of Asbestos Fibers, Sari S. Flowers Discussion on Chemical Detoxification of Asbestos Fibers 475 476 477 432 489 497 NATURAL NON-FIBROUS SUBSTITUTES Health Consideration* In the Perlite Industry, V. Clark Cooper Discussion on Perlite Review of thu Health Effects ofKicas, Ilmar Lusis Discussion on Mica Health Effects of Vermlcullta, James Lockey and Stuart M. Brooks Discussion on Vermlcullta 505 511 513 554 555 580 Talc: Roundtable Discussion (Evening Session) Opening Remarks: Natural Non-Fibrous Substitutes: Talc, Arthur M. Laager 563 Cross-Sectional Epidemiologic and Industrial Hygiene Survey of Tele Workers Mining Ora from Montana, Texas, and North Carolina, John Gambit, Alice Crelfe, and John Hancock 570 Roundtable Discussion on Talc 612 SYNTHETIC NON-FIBROUS SUBSTITUTES Occupational Exposures in the Ifenufaecurc and Application of sol7ureehaae and Uraa Formaldehyde Insulation Systsma, Robert f. Herrick, A. A, Aleerase, R. P. Reledorf, sad D. W. Rxasey Discuss ion on Fossa Hi*an Pulmonary Function Study (5 years) on Occupational leocyaaate Exposure, Hans Weill Discussion on Isoeyaaate 62! 666 667 652 CRITERIA POt CVALUAXIMC SUBSTITUTES Criteria for Animal, Tissue Culture, end Biochemical Studies on Asbestos, Mineral Duets, and Proposed Substitutes for Asbestos, Eerl S. Flowers 653 003762 txtiner RMC0006516