Document O1m4j2LvGkvErJ8m4ZY8wbB6K

.3M SKaatlhVeirienEPer.eRseeendt. PhD. 3anMdEnSavfiertoynSmeernvticaelsTechnology iP DEW -20 - 3/3 90Bu0ildBiunsgh4A2v2e5ne26 POPBaoln i33y33155333 S1743 Chia suns mess AR 226 _ 108] TL . "17 i5 February 28, 2002 &HR - 03300,2 _ 00373 cBl EDoPcAumEaesntt-PrRoocoesmsi6n4g2C8eAntttenr:(S7e4c0ti7oMn)8() Contain NO UOfSfiEcePoAfPollution Prevention and Toxics W1a2s0h0iPnegntnosny,lvDaCnia20A4v6e0,-0N00W1 TSCA (E) SUBSTANTIAL RISK NOTICE ON: Ammonium Perfluorooctanoate CAS#: 382526-1 Dear Sir: ; p8e == 3o8n 22 = 335 C3AMS#h:as r3e8c2e5i-v2e6d-1in(foArPmFaOti)oniniannadOrraaflt(fGianvalagreep)oTrtwoo-nGeAnmemroatniiounm(OPnereflLiutotreoropcetranGoeanteeration) oReuptrcoodmuecstifornomSthuidgyh-idnosraets(,3b0ymgA/rkggu/sdRaeys)emaarlcehsLaabnodrafteomraileess,: identifying the following, 5A2sl2ighptosbtu-tpsatrattiusmt)icfaolrlyFs1igpnuipfiscawnhtidcehcraepapseearisntloacbteatsiporneianddaecxr(opsesrsceevnetravilalbiiltietrys afnrdomisday `Anotslaipgphatrbeunttlsytatsiesxtiscpaelcliyfisci.gnificant increase in carly post-lactational deaths in F1 females p`Aotselingchyt)biuntFs1tatfiesmtaiclaelsl.y significant delay in sexual maturation (as measured by vaginal `AA ssliiggnhitfibcuatntstdaetliastyicianllsyexsiuganlifmiactaunrtatinicorne(aasse mineaessutrroeudsbcyycplrienpgutiinalF1sefpeamraalteiso.n) in F1 males. i3sMcubrerleinetvlyesatwhaaitttihnegsreeseuflftescotsfmcoavyarbieateexpalnaailnyesdesfutlhlaytowrililnppraortvibdye bionfdoyrmwaetiigohntoanndthaegec.ffe3ctM pofrbemoadtyurweeitoghdtraanwdcaongcelounsitohnessecopnacreamrentienrgs.theUcnatuilsatthieosneofatnhaleysseesmaarregianvaali,labbulte,stitatmisatyicablely bSiegnsiufbimcianttt,edeffteoctEsP.A.A final report for the study will be available within a few weeks and will For further information, please contact Dr. John Butenhoff, 651-733-1962 Sincerely, wi &. Led StKaatflffVeriicnee EP.reRseiedednt, Environmental Technology and Safety Services fi epa-oTs 000811843p