Document O1QRdyKQD6e97r0RML9jdEQxj

BACK TO MAIN 3M FLUOROCHEMICAL SUBMISSION TOXICOLOGY, EPIDEMIOLOGY AND MEDICAL SURVEILLANCE ATTACHMENT TO LETTER OF 1/18/05 Click on Study Title to View Report Multiple Chemicals Page: 1 1. "Inter-Species Comparison of Mechanisms Fluorochemical Toxicity following Intraperitoneal dosing of perfluorooctanesulfonate (PFOS, T-6295) or ammonium perfluorooctanoate (APFO, T-6889) in Rats and Guinea Pigs and oral dosing of N-ethyl perfluorooctanesulfonamido ethanol (N-EtFOSE, T-6316) in Rats," 3M Medical Department Corporate Toxicology, DT15-A, May 24, 2004. 2. Molecular Biology Study: a. Final Report, "Comparative Molecular Biology of Perfluorooctanesulfonate (PFOS, T-6295), N-Ethyl perfluorooctanesulfonamido ethanol (N-EtFOSE, T6316), N-Ethylperfluorooctanesulfonamide (N-EtFOSA, T-6868), Perfluorooc tanesulfonamido acetate(FOSAA, T-7071), and/or Perfluorooctane sulfonamide (FOSA, T-7132) of in [sic] Ratsand Guinea Pigs following Oral dosing," 3M Medical Department Corporate Toxicology,DT-15-B, May 25, 2004. b. Amendment to Final Report, "Comparative Molecular Biology of Perfluorooc tanesulfonate (PFOS, T-6295), N-Ethyl perfluorooctanesulfonamido ethanol (NEtFOSE, T-6316), N-Ethyl perfluorooctanesulfonamide (N-EtFOSA, T-6868), Perfluorooctanesulfonamido acetate (FOSAA, T-7071), and/or Perfluorooctanesul fonamide (FOSA, T-7132) of in [sic] Rats and Guinea Pigs following Oral dos ing," 3M Medical Department Corporate Toxicology, DT-15-B, July 16, 2004 (revising page 59). 3. Cell Proliferation Study: a. Final Report (except for in-life appendix), "Cell Proliferation Study with NEthyl Perfluorooctanesulfonamido Ethanol (N-EtFOSE; 3M T-6316.11), Per fluorooctane Sulfonic Acid Potassium Salt (PFOS; 3M T-6295.16), and N-Ethyl Perfluorooctansulfonamide (N-EtFOSA; 3M T-7091.1) in Rats," Charles River Laboratories, TRC 1132-100, August 9, 2000 (amended November 8, 2004). b. In-Life Appendix, "Cell Proliferation Study with N-Ethyl Perfluorooctanesul fonamido Ethanol (N-EtFOSE; 3M T-6316.11), Perfluorooctane Sulfonic Acid Potassium Salt (PFOS; 3M T-6295.16), and N-Ethyl Perfluorooctansulfonamide (PFOSA; 3M T-7091.1) in Rats," TherImmune Research Corporation, TRC 1132-100, May 2, 2000 (Appendix 1 to full report).