Document NeXExZ9rrjGVbr54q6L00yd5R

WATER SOLUBILITY PART RIA8 CCOONTTAARIR NONr Ca TEST SUBSTANCE Identity: rNe-fmeertrheyditpoerafsluNo-rMooecFiOanSeEsAullcfoohroalm,idFoCe-t7h9a0n,olo;r mFMa-y3a9l2s5o,be(1hOecpttaandeescuafllounoarmoi-dNe-(,2-Nh-ymdertohxyyelt-h1y,l1y.,2C,2A,S3,#3244,444,85.-,059,.67.)86..87.,87 Remarks: 3MaMtelroitanluims baenrof5f0-5w.hitPeu,riwtayxiynfsoorlmida.tioSnamwpalseowtasretcaokrednedf.rom METHOD: Method followed: TMh.eCoVmesittohc-Cko,mJs.tFoicskhtReecsh.niBqouea,rdG.CaDn..Ve3i2t,h 1a8n4d9V. GLP: No (1675) Year study was performed: 1978 RESULTS: Value (mglL) at 18 + 1C: 0.62 tRheemsayrsktse:m_forIn2i4alhovuarlsueisndfiocrastaetduarastoedlusbolluytioofnasprpersouxlitimnagteflryom2.c3irmcgullaLt.ingIt whiagshesrustphaencttehde tshoaltutbhiilsynoufmtbheercwloasseliynraeclcautreadtemaatesriitawl,asN-cEotnsFiOdSeErably ahlocmohooll,oguSeisncaereifpsrekfneorewnntitahlalty swoaltuebri-lsiozleudbbley tihmipsurtietcihensiaquned,stohemesaturated whaoutresr.waResplriecpaltaecesdolwuiblihltfyrevsahluweasteorfathnedrweacisrcaulllaotweeddsotlourteicoinrtcuhleante for 5 indicated a solubilty of 0.82 ppm. CONCLUSIONS: The test substance is relatively insoluble in water. DATA QUALITY: qReulailaibtiyltietsyt:ingK.iiTmhisicshsrtaundkyilnagck=s3.sufTfhiicisensttucdhyardaocteesrinzoattimoeneotfctihteetieastfor SAdudbisttioannaclelyp,utrhtey.seTchoendprcoiprecrutliaetsioonfofthferetesshtwwaatteerrfworeroenlnyot5 hnootuerds.without taonydefsianmiptilvienlgy cdounricnlgudtehatthiatmtehepesroiloudbiolrtyfoirs e0x.t8e2npdpemd.tAilmetshoiusgihnasodleuqbuialttye 006509 `apparently plateaued between 4 and 6 hours initially in the first 24 hour ciymcpluer,itiitedsoeosrnh'otmfoollolgowuetsha.t tAhddeistiaomnaelleyf,fetchterwiellwoacscunroiindtenhteifaibcsateinonceofofthe thhoemyoalroeguoenlsyoproismspiubrliytiiensteirnfetrhiengswaimtphlet.he TshoeluibrilpirzeastieonnceofiNs -amsestuhmyeldF,OtShuEs alcohol. The extraction efficiency with ethyl acetate was not cdheatreaccttoerriiszendo.t aTnhaleyatnealsypteicciaflicmteotthhoedtwaragsetnaontavlayltieda(tFeMd-.39E2l5e)c,trtohnerceafpotruere peak used for quantitation may not be target analyte. REFERENCES: This study was conducted by the 3M Company, Environmental Laboratory, 1979. OTHER Submitter: 3M Company, St. Paul, Minnesota, 55133 Environmental Laboratory, P.O. Box 33331, Last changed: 5/17/00 006510 Fmenariia TECHNICAL REPORT SUMMARY TO: TECHNICAL COMMUNICATIONS CENTER -- 201.20N Important = 1 reportspind onbothside ofpaper,send twocopiesto TCE) "1/8170 = Environmental Laboratory. (EE & PC) 0535 Premanufacturing Notice FC-790 9970012600 Solubility of FM 3925 014 V. Pothapragada A. N. Welter/Bii-Aw;Reiner) 09362/47816 NB 48277-8; See Environmental Lab Request 4197 SATIS LO ctor) Tears |"SERIE onGhee wemoonnos:oma Comment GRECTIVE: pa Soames ath To determine the water solubility of FM 3925 (Lot 505). EE& PC Div. (Environmental Lab) Fluorochemical REPORTABSTRACT: {ozs0wonds)This.torainformation sditriutedby`the Technical Communications Center to Solubility Studies vo oe he ial materia. (Veith Technique) quo go1upility of FM 3925 was determined by a method in which water was recirculated from a reservoir through , a column containing glass beads coated with FM-3925. Analysis of water samples showed that the FM 3925 1 c&ohnocuernst.ratiSoinncerewaactheerd asoplluablteeauimopfur1it2i.e3smga/ald maotre4 to * soluble chemical homologs are preferentially solubilized by this technique, the saturated water was replaced with fresh water. The second sequential circulation of water gave an FM 3925 solubility of 0.82 mg/l. value is considered more realistic. This solubility [HErA--TLY 006511 3 . Introduction FrMeas39o2n5a,blybasbeed eoxnpecittsedsttorupcotusrsaelss ssiimmilialrairtyphytsoicFoMch3e4m22i,calmay scohlaurbalceter(i0s.t0i5csp.pm)Thaendllaitptoeprhicloimcp.ound is minimally water Tofechsnoi-qcuaelsledhavheydbreoepnhobdiecvemlaotpeerdiaflosr wdheitleermiantintghethseamesoltuibmielities providing saturated solutions for exposure to aquatic organisms. TahemoddiaftiacaitniotnhiosfretpheortVeirtehfl-eCcotmsstotchke treecshunlitqsueofhsastudbieeesn; uwsheedreiinn, determining the water solubility of FM 3925 (1). Methods Tmhoedemleedthoadftearnd thaaptparofatuVseituhsedandin Codmestteorcmkini(1n)g. watIen rbrsioelfu,biwlaittyerwaisn caulraetsienrgvoitrheiswatceorntitnhuroouugshlyasbaetduroaftedanwiitnhertthesubcshtermiactael ibmyprceigrn-ated with the chemical under investigation. Wtaetmeprersaotluurbei-lciotnytrostluldeideschwaemrbeer.car2r0i0edmogutFMat392158+wa1sC.disinsolaveddarkin rgleaasgsenbte-agdrsadeandaceatlolnoew.ed tTohisevaspolourtaitoenofwafsinthernoomaddaierd. toTh2emmcoastoelidd egnldasswitbheadrsubwbeerresttohepnperpsackceodntaiinntoinga gsluaistsablceolgulmassf-ittote-dtuobninegach connectors (2). (Attachment 1, Environmental Laboratory Protocol.) . O8,ne ahndun2d4rehdou(r1s00)afmtlerwabteegrinnsaimnpgletsheweerxeperwiimtehndtr.awn Atat241, ho2u,rs4, 6, " : cfurleasthiowna,terrewpalsicaatdededsamtpol_etshewesryestweimthadnrdawfnollfoorwinagnal5yshiosu.rs ArLeLcir- 5 water flowed were retrograde: from bottom to top of column. SRagmcpklaersd wMeordeela5n7a1l3yzegdasuscihnrgomathteogrfaoplhlowwiitnhg meeltehcotdroolnogcya:ptuHreewluestitn-g CarNbiowaasx t2h0eMosnourCcher.omosCoorlbumnWs-AW6' 60x/810/8"me0s.hD.. TSSe,mpepraactkuerdeswit-h. 10% DIestoetchetromral3;00floCw.:, In4j0ectcico/nmint.em9p5e%ratAurrgeon2/050% MeCt.,hanOev.en A-bs18o0luteC. lower detection limit - 0.5 nanograms. Results and Discussion Wpraitseer TsAoBlLuEbil1.itieCshroofmatFoMgr3a9p2h5icas traacfeusn,cti1o0n popfm exposure std., 6, time com 8, and 2r4ephloiucrast,edofvaltuheesse arreesuilntsgooadre appended agreement; as Attachment 2. The 006512 , i". TABLE 1 WATER SOLUBILITY OF FM 3925 - VEITH TECHNIQUE Sample Time, Hrs. 21 a6 248 ppm FM 3025 11..7920,, 11..8827 22..1303,, 22..1370 22..3147,, 22..1345 Wrheecnircfurleasthewaftoerrfwiavse haodudresd, toretphleicastyestseomluabnidliatlylovwaelduetso of 0.82, 0.82 ppm were obtained (Attachment 3). Trhuen vvearrsiuasbiltihtaty oinbtasionluebdilaifttieerstohbetaaidndeitdiodnuriofngfrtehseh2w4a-theorur 2ma4y-hboeurexrpunlaisnamepdlebsy. theItpriseseknncowenofthattrawcheenimtpeursittiinegsmaitnertihaels oifmpuirnihteireesntlmyaylboew smoolruebisloiltuibelse, thiatn istheposmsaitbelreialthautndetrhestturdayc.e Tihmepurrietciiersc,ulahteencdewahtiegrhewrilalnaltyhteincatlendvaltuoess.olubUiplonizethetheaddition tofracferesihmpwuraitteirest,o tahmeorseystreemaliasntdicinwattheerpsrooblaubblielitaybsevnacleueofof 0.82 ppm FM 3925 was recorded. ' " References: (1) SVeaittuhr,atGi.ngD.Wataenrd wV.ithM. HyCdomrsotpohcokb.ic AOprpgaarnaitcusChefmoircaClosn.tinuously J. Fish Res. Board Can. 32:1849-1851, 1975. (2) Environmental Laboratory Water Solubility Protocol. aw ANW/EAR/ cen Attachments: 1, 2, 3 006513 Attachment 1 a 1/8/79 34 ENVIDREOTNEMREMNITNAALTIOLNABOORFATWOARTYERPRSOOTLOUCBOILLITFYOR THE Discussion: mA(ipxattrrutuericelseoofludtitiawoomnetoemrraymoobrfee lsedusesbfsittnahenadcneass1" OaM()1",)p.hnyosiIhncaeltaleyrtorguheeonmesoiogtleyunteiocouansn* bbey mdeectheacntiecdalandmeasnosl.utesIncagnennoetralb,e msoesptaroartgeadnifcrocmoemapcohundosthearre ncootllosiodlaulbledisipnerwsaitoenrsan(dpamratniycletedndiamteotefrosrmbectowleleonids1. nmInand w1iuml)l, stcheatptaerrtilcilgehst m(aTyynndoatllbeeffreecatd)ilyanddisccaenrnbieblsee,parbuattedthebyy physical means. Amorseatusorlautteed wsiolllutidoinssoilnvewatateraisgidveenfinteemdpearsatoumree,inorwhitchhe no cchheemmiiccaall ppootteennttiiaall ooff tthhee udnidsissoslovlevdedsosluotleu.te equals the Tchheemipcrailnciaptalsamteurtahtoidonforisdetoteramnialnyizneg tthhee ssoolluutbiiolnitybyofsomae sauviatialbalbelephtyosiccoavlerorthecheemnitciarle mreatnhgoed.of Nsoolsuibnigllietiemsethiondwaitser cfhreommicraellsa.tivTehleyresfoolrueb,lesoervegraanlicmecthheomdiscalcsantboeveursyedintsoolcuobvleer wtahse mroadngeeledofasfotleurbitlhiattieosf. VeTihteh maendthCoodmsatnodckapp(a2)r.atusBricehfolsye,n > . water in chemical bay rceisrecruvoliartinigs cthoentiwnautoeursltyhrosuagthuraatbeeddwiotfhantheinert 5. sEuxbpsetrriamteentsimparreegcnaartreidewditohutthien cduhpelmiiccaatle.under investigation. Ftoiornvetriymehsytdurdoipehsobiacrechceomnidcuacltsedwhtiochensfuorrem ctohlaltoitdrsu,e scaotnucernattreadeplqautielaiubriinumssucohlusbtiuldiiteys.has been reached as evidenced by a Tahetemapppearraattuurse-cfoonrtrtohlelseedswoallukb-iilniteynvdiertoenrmmeinntaatlionrsoomiswhhoosuesed in ctoenmsptearnatturteemptoeraptruevreent(uhsyudalrloypho1b8icC icsomkpeoputndsbelforwomtphraetciopfitraotoimng, tcroangnesafleirnrge,d ofrroomthtehriswiseenvicroomnimnegntoault orfoomsoltuotitohne olnacbeoraittoriys for wfouurltdherbe amnoarleyselsi.kelTyheifpotshseibrioloimtyteomfpersaucthurean isevebnetlowhaptphaetnionfg the environmental chamber. 006514 Cas : .- -; Attachment 2 AitTtInF 29 ize REJECT 15aa in 2%>% sot. AT bHR. gx 9 s. a ia EEE) Ra ban --_ =mee ; ror 554 : Amen x 21R2T TYPE iRAE RER ei Iis4ua TM T 173T64132479 23%P%) 34 . 24 bwev 313208 Wein ie AsTtToNr 20 ize REJECT 1000 PMv428 LL. AT=8 HEL. qy1-9 < 2 1s 5.63 "23g 34 o ca 11. 53% : Too . v By BESTCOPY AVAILABLE an ss sto S:r LTE; < ruse axes sgn x . Tages isa 3 = vo TE1T:T2I2E30%4 C4roan) 5331 - "TTTTIs3v = nr 14.22 006515 VRE sven CmLeeryn 2, ae LAE Suita land oosTATUTRN ae 128 (VEL CREJE5% CT 1660 : ppm F-39285 i 3 Ss es fn E E 5 et FoaR l rEReG Hoa Hepger blinds ay G MERIPE r Dini e nCENSARtEeR eHL T a ER : DFora ie e iiwae ahiEstaddsaseniiilei llLRu geea s ai llaa s og gte : Ai Re FE TH 536234 1855/00 89 A Tagger 9) 46 Gi Ae es an e AA eA ER a Re bLy 2 nvm ae CSTOPIYS ATTN "128 REJECT, "1000"! lv Hil, yp ye ERE FINS cor. ATaadMEs gad Sa CN LT BEM AE : at -- FRR Re - Eh Lr ER TE ee a a EE 5 SE RES ri 2 Taare a ees E TAZ a rn ReaRlet id > Watiad 0lsat - sp ni ne ER TR a 33 5 bi STOP. FiE talien ARERS R TE RT TYPE REN Ly TT a g BESTLOPY) vi 3 MILABLE NEE . i F3oleas2 4:99 CTH IN 2138570670177CryS8m10e 87 eE haG nR ger+ TH vageRes. Cl US ans lier 6.48 To Shin 2eeg HEL UE asa bined ME SEsEN EE A 2 aifl STORa de Ch REETdea el HAG 16 - Ga mi ll Si N ngS gCnT hSa E Et IN haRE m ee ee R EReC a NcSn eS n E E ETE T ON ER ERR GLRA e AL Lp R odRx 7L CS e Tene e a TRUER LG SRR CA - or Attachment 3 LC "LngOnNsmagEa SREA LL x pron EERIE we 3s oo lak a 315 ae mo4ieeetigeaag a5r5e0nF 15 ia REJECT 1000 PASa t>S su. au 8a pT30C1U-E0.(GVAP) s. STOR? oPzT ype Pim S2.5452 qTnTM Siam HT otizag Lue g Nom ta 3. + 02 4.99 77A3R5E7A7 mE 8432227575 53302 AREA 2 20.820" STOP 19 ATTN 128 [ Ar Te3r EA Sr T 4% 00 a 87 23.93 +322E.338r"4 2372 BESTCOPY AVAILABLE LL REJECT 1800 Lu ST vy 3 - * sud pe Ave togn" TOR LT. tees sion : 3' * iin IE wan agen REA 3% ER Frith O.B2ym IEE. nnahs Iisz :i 006517 FaEm rn TECHNICAL REPORT SUMMARY 7 TECHNICAL COMMUNICATIONS CENTER -- 201208 mportant = aortic anbotsidesofpp,atwocopies 0TC. Environmental Laburatory (FE & PC) = Fate of Fluorochemicals we --fAR.nRaYLlL.yItiBccataclonJMeetthhooduvnlloongyyaannddSSwueppeorrtt eel Arthur Mendel 41947, 44191, 46209, 47703, 48277, 49400 i TIonce:mo Cone oRoe TvE R EEE | progres meport LFElu&orPoCc-hDeinvi.cals TTT " Tare 0535 08 9970612643 r-- i 043939 28 Ea ee sz oC A rr RETer SN ------ & inn senJ i 006518 | = BEST COPY AVAILABLE {TLiC5aOzFz(Bi1o7d7eg0r3adat6-i1o4n. S21t,udiBeSs2oTn dMaed;ionBcotaivse iFeC)-95, FC-143, and DFIainneldt3at4ieh2tel3hs,yblorfeasnaedctnehttecaowtnboetiriuknde,iexsgtrrtaaahcdreteastniidonegnesetcnereseirtnbuadetidesedasmipnflorneEo.smlbeAu.iavocedhlReeegdifrnraeoFdwmCa'-ts9si5l,ourndegpFeosC;rt-t1u4wd3it(,eeiss),. vGafu0eit1rro)ser.taadbpiyTpohlgeuirleapptdhlryaad.tvi"eiroselcTetvhtleeyretpitlgodhaetptvelesal(tolwepoesenrdge(a2inne0xxd2pe0otSshheyoodlrm.t atwocE.aevKteoaMdlteaeerkncgktthxhe-OsnrFayae35nx4daHmi8itmihnelenidfeoabry oWniethweceokn,troalnasathmeple[siininwdaiscattheednnodevSeilgonipfeidcaanntd edxiafmlienreedn.ces.Comparison eIttnxohteracaoucsnntevnceeortfnthrdyolannpayattrhetendonouVfvnaodrlitaomhtueiisstlheyeslxapamceptorlemiedpmsoensnewatnim,dtpslemasetptoowhreyGrtlCeiaotvneothldeaonftwiilttaehhneadSlpeyietsahcesyidglemsbe.ysancaefantBseaotthe cSahmrpolmeast.o"graGpChyc.ondiNtoiodnisffearreencdeestawielreed ninoteNodtebbeotowkeen47t7h0e3s4e3.and' control Dstormination of lhe Solubility of.i-Nothyl FOSE Alcohol FM3925 (48TT7-8; 46260-5.: 42660-4) : Ahsobomolouvgteedn2e0ionugsaobfoSuatFmMp2l03e0925mlThLoeotfco5ro0el5aegdwe,natssomwleriladtdeedmaatc(eesrttioeanalem,, ba2at0nh0d) mteht.oisowebsstoaliudntiiso.an WcTahnsl"ouraodUtodouerkdno,rt.o "apcPreehtcoeinwos,anWoewrdaet.e4prr,momcmeGstlahaanmnccoile,rsuuacnoodin1adtiheKhnloalykasthwhbadirnh ideshde:cpotnaTinhaeeined FaFUnUdbb3so0ur2p5pSoctrootpaeptederdsbygwliaanrsso abceowanodnsoelcvtee(rdpsresBotlraoBcseevtdoehdiinwneit3hVIegGllatasunsntirnceeoaltualgn)nd. u(3np0og0s1i8oeinadmlm)eic PEwGxnuaptlmoikprr-ieiwnnaessneottnu,uvspierdwowanattsmoeornRLtwoeaanulsdlucaprtuotemoedpmedd(in1e[8tto3ohr1ne0s3)sddahrokwurraistioenrr(ah.trLeto"huergmthpohemrLaShettihauersr.eeetccuocopfol,nustmr`hnsoennldleThde tFilhmipsu3r0wi2ta5iteesr'"wFTrihesasthdwwiioxctuaelrrddewbdae.sastThehSneoluppbullraepcoesdaes.ionfotertMhtoihserewsaSyso.sltutoeb.leraenmdromvaaent'. ainnytervals tqS(huaSeaetenutmriaTaitatnabeltdei2v-aeql3l)ui.yetoeur1ts0r0uNninsoomllrdaeigur(emrveodcclhhualmtmooebrleirArdi.ecsewppa`aiEspraeacltha)oarodyfeofd tfWhufeanotnlee1llr0o,0vweadmaiynbdywsai1mt03ph5ldmerimsa1wonfworasfrom TGPtihthnaeha"ysleOGrawyuaauecsoneuitsaGctUeApp,RhhCaaLssCeeTIhLowwiaavnsmeilxarytduderetxedrraanwtcsiotsfaetderhxortwcird1ta0hc-tmtole4damola1l0nuo-dmfmelttehrtevihoyelsluenp[cas}rrcaeaenitktcs.etdwehf.So1sratesakan,ndic dvAeoTtl1euqcnUtsootrwawsaa.sgd[uisanedaSilnl-oTbrorboKtuigsh(sc1h.r5toommtothotekermruaprhkCyowliuutsmhinSegEthagnCiaerlbseoccwetetrsnoienC.HcOaUpmnture | run ar iso'. "The Tomuite are' reported in Table 3: 006519 -21- : i i BEST COPY AVAILABLE ! Table 3 | 2 Solubility of FM 3925 in Water | Time of Water Circulation (hrs.) FM 3925 (ppm) | 21 111.9702;; 11..8827 4 2.10} 2.17 !: 65 220.3333}; 220.3350 : 24 2017; 2011 i TThhee the gsraoesltuebnctihilroiontmyattioomgferaFopMfhi3c9F2Mp5a3t9it2se5rfnoisnrt(cysl-eosesiexFitLgoiumreCeshat2thaoitnf oWfM F24M233,422a.nd releremce 1) are essentially the same. REFERENCES ` (1) "reApnoarltytitcoalD. MeL.thoDadcoolno,gydoantedFM113/41252/,7"7,A. p.Men8.del's progress : (2) D, B. Basty (i977). und i. a. Wabers, mnalytical Letters, 10, 857 J | (3) FMIUanrtc3eh4r2o22f6.f,"ice1T9h7cGeo.rrdeeinssttpirotinbldueetdnicoe"nGaoscfoeCG.fhfrioAc.miaetVnortgarsapipsihridcetfoiAnnD.eadlyL.sasesBatcohofen, prhaatsieo phase otfo at atthheegivcreounnnccepeinnlttrr(aauttsiiuooanlnlyooff 7)ca.lolmposupnedciessoluibnlethein aqnu-eoocutsanol |i| (4) A. Otsuki and K. Fuwa, Talanta, 24. 584 (1977). i (8) EG.nviT.ronW.allSaecie., ucJra.i,in,I. AS1,3 4F9l3etc(h1e9r7,7).and R. A. Duce, J. . (6) 3G2., D.18V49eit(h197a5n)d. V. M. Comstock, J. Fish. Res. board Can., i (7) 9K0. OFW.. SHaerigneenta.nd(UR.apuRb.l Biusrhefdo)rd, C. G. Klaus, J. D. LaZerte, i - : (8) NA.ov.Men15d,el 19r7e7p.ort on Fate of Fluorochemicals to D. L. Bacon, : (9) EC.nviT.ronCmheinotu,al V. sivlii.cncFereeadn,d TD.ech.nolSocghym,edd11i,ng47a5nd(1R.977L).. Kohnert, _ hae 006520