Document Nd7yYZQL7Bdq0VL0NE8oORxE

COPY _ Dr. R, A. Kehoe FOOD MACHINERY aND CHEMICAL CORPORATION WESTVACO CHEMICAL DIVISION Chrysler Building East ll East 42nd Street New York 17, N. Y Francis F. Heyroth, M.D. Assistant Director, The Kettering Laboratory University of Cincinnati Cincinnati 19, Ohio Dear Doctor Heyroth: On my return from a vacation trip I find your letter of October 7 awaiting me8 I am pleased to note that you approve of our general program of toxicological screening prior to pro duction or use of potentially toxic materials, particularly conomie poisons. I read with a great deal of interest your discussion of the relative merits of oral versus intraperitoneal administra tion of these compounds. At the present time we are making frequent use of both methods on the same product and comparing results. I think it may require some little time before any general conclusions can be drawn as to the relative, advantages of the intraperitoneal method as compared with the usual oral, inhalation, and skin contact tests. . In any event, I take this opportunity to thank you very much for your reply to my inquiry of September 30. I trust you will convey my kindest regards tc Dr, Kehoe on his return from abroad. . Very truly yours, ` WESTVACO CHEMICAL DIVISION /s/ Frank S. Low Frank S . Low FSL:hm N14009 KE 00323 i 2