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HE 0018489
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From *hf* history of recent lwpitaxisatIon of
one asRumes that he has not worked since >*5
he seems In a different category front that of the others and is
dealt
?>erarately. Th$ levels or lead concentration in his
blood <v<U uriae .`ire within nonsal limits at this tine# What they
were Vue -..tfcio hv Quit work cannot be guessed except on the
assitrwtion Vosve. If Vale assumption i3 correct, his exposure
tfuriu:.; the juried shortly prior to >25-52 was not very severe.
If, however, he had not been working: for a much longer time -
i.c. , for a y ; or oosnsvhat non* or less - his exposure may
have been quiie ^vere. Only on the basis of a knowledge of
these fads coo t.he present results be interpreted.
fj .y*>*' --s - leal data on each of the other men hde provided some
evidence o.f unusual ttxposure to load, the rsevurl 7 cf which deci'c^Jev Ij chc order in wHlch they are named.
>h?u: been subjected recently to an hazardous type
of exposure, wo shovn by the fact that the concentration of lead
in his blood ii- in the desgerou* range associated frequently with the iiynptcma rclogy of lead poisoning. His urinary lead level is elevated b.it nit f-o quite a corresponding extent. This man should be removed f *o further significant exposure promptly and should not vo rcxurnc-i to wor;;> involving further exposure until the lead
level h?ive cx-orped to normal or near normal.
has been subjected to exposure to lead, but at
pret t2/ iiasi not "reached a dangerous level of lead absorption, Whether or not he is likely to reach a dangerous otate in the near f vi /axe con bi; determined only by consideration of the de t *> of his recent employment* He would not be expected to develop symptoms without further significant exposure.
gives no evidence of dangerous absorption of lead. The urinary lend concentration is elevated but little beyond the extreme upper nossaal limit (for a sample of this volume) * while the blood lead concentration is at the upper normal level. 'These results/ point to recent exposure, but the absorption up to the present ties not exceeded the limits of safety.
Signed J
Ke 00184 S-0
1S19677.01
June 2, 1952
Dr* L. H Hergesheimer Plant Physician K&tionai Dead Company 2607 E. Cumberland Street Philadelphia 5# Pennsylvania
Dear* Doctor Hergesheimer 5
I am sending you herewith the results on the blood and urine of the following patients, together with an interpretation of the results and an invoice covering the cost of analysis:
ef Enc.
Very truly yours,
E. H. Fortiage, Secretary to Dr. Kehoe
0018491
N19677.02
REQUEST FOR STUDIES AT KETTERIEG LABORATORY
Lane
Color B Sex M Ag^2
Address
IbOl N. 18th St., Phila. 21, Pa.
Request by L. H. Hergesheimer, M. D.
Hospital # Date 5/21/52
History
Negative. Specimen submitted because of increased number of stippled cells in blood.
Physical Negative.
Laboratory
January 1952, hemoglobin 80.
April 1952
" S5%.
22 stippled cells in 30 fields.
50 "
30
Impression Chronic lead absorbtion.
Treatment None
Studies Desired Blood and urine lead leyels.
KS 001842
N19677.03
REQUEST EOR STUDIES AT KETTERING LABORATORY
N ame
ColorW SexM Age 46S M W D
Address
j Phila. 34, Pona.
M^arrxied
Request by L. H. Hergesheimer, M. D.
Hospital #
Date 5/21/52
History
Negative. Specimen submitted because of increased stippling of red cells.
Physical Negative.
Laboratory
April 1952, hemoglobin ?5.
May 1952
" 80^.
19 stippled cells in 30 fields.
49
30 '*
Impression Chronic lead absorbtion.
Treatment None
Studies Desired Blood and urine lead levels.
K 001S4'.'3
REQUEST FOR STUDIES AT KETTERING* LABORATORY
Hame Address Request by
;51 Crease Street, Phila. L. H. Hergesheimer, M. D.
ColoiW SexMAge^lS M W D
25, Pa.
Single
Hospital #
Date 5/21/52
History
Ho symptoms. Specimen submitted because of increased stippling in red cells.
Physical Negative except for hypertension.
Blood pressure 172/100.
Laboratory
January 1952, hemoglobin 80%
March 1952 April 1952
tt B5%
22 stippled cells in 30 fields
y it
it tt 30
50 >
30
X-ray shows probable pneumoconiosis.
Impression Chronic lead ingestion.
Treatment None
Studies Desired Blood and urine lead levels.
KZ 0018494
\. REQUEST FOR STUDIES AT KETTERING LABORATORY
11 ar.e
Address
Z570 Collins St., Phila. 25,
Request by L. H. Hergesheimer, M. D.
Color WSex HAge56S M W D Married
Hospital # Date 5/21/52
History
Recent hospitalization from 3/25 to 4/28/52 for nausea, confusion. Periodic vomiting for one year with chronic time no complaint of pain, normal bowel movements.
vomiting, fatigue and anemia. During that
Physical
Confused, mentally sluggish, B. P. 200/100. Enlarged heart. murmur. Enlarged liver. Neurological examination:
Systolic mitral
1. Quantitative intellectual deficit with dulling. 2. A left hemiparesis, 3. Marked hyperactivity of the tendon reflexes in both lower extremities and
diminution of position sensation. 4. Slow measured gait with some unsteadiness on turning & mildly positive Rhom
Hemoglobin 8.4 gm. RBC 2.7 mill ion, K3C 5,100. Bone marrow shows many stippled cells and over active granulocytes. Blood sugar 87, urea 70, C0 45$, chlorides 594, protein 6, serum albumen 3*2, serum globulin 2.8, blood cal cium 7, blood lead level 0.201 mgm. per 100 gm. of blood. Gastric analysis; Low total acid with no free HCL, x-ray of intestines, chest and skull, negative
Impression
1. Chronic lead poisoning. 2. Nephritic, chronic, glomerular. 3. Hypertensive cardio-vascular disease. 4. Anemia, severe. Secondary to No. 1 and No. 2.
Treatment Digitalis, Unicaps, feosol.
Studies Desired Blood and urine lead levels.
KB 0018435