Document NG76BdGpjnNJp01wXrnMpavnV

SUSGECY' WUUAM 9. MILLBERG. M. D. MORRIS WASYUNKI. M. D. GENERAL PRACTICE GLENN E. E1PPEST. M. D. RICHARD . M1LLBERG, M. D. - 4 as m T IMTBtNAl MEDICINE ' >'; MOHAMMAD T. HOSSAIN, M. D. CHARLES M. SUTTlS, M- D- December ,13, 1973 *' '"-'-Robert W. Pringle, M. D. - Pittsburgh DiagnosticClinic . :/ Mellon Pavilion : 4815 Liberty Avenue : - ` Pittsburgh, Pennsylvania 15Z24 ie Dear Doctor Pringle: Enclosed Is a summary of the sixty employees of the North American Rockwell Brake Division, Ashtabula, Ohio, who underwent pulmonary function evaluation at the Ashtabula Clinic during the year of 1973. The rationale for the study is presented, the methods of Investigation are discussed and limited conclusions are made. , We feel very strongly that a cursory, evaluation would serve no preventative purpose in the early detection of such a protean and insidious disease as asbestos pneumoconiosis. For this reason we have recommended a more complete evaluation. - A limiting factor In this initial study pertains to the comparison of observed date with that of predicted normal values. Although worldwide recognozed predicted values were utilized, the information obtained cannot be compared with that of serial Individual determinations. The importance of comparing an Individual with his own established values is paramount. During the ensuing year this will be accomplished and the investigation will be of far greater value to North American Rockwell Brake Division in that changes, not expected by age increase, will be detected. This we hope will'' result in early detection of a possibly correctable disease. . . Since asbestosis is primarily an interstitial disease, we would highly reconwend the addition of diffusion studies to the present program. This parameter appears to be the earliest effected in asbestos exposure and would inhance th-e early detection of abnormality. With the addition of i ROCK 0006695 Robert VI. Pringle, M. D. Page 2 December 13, 1973 diffusion studies (single breath arid--if 'necessary, steady state carbon monoxide diffusion test) we feel that your surveillance program would be most complete and satisfy any critical Investigation. If you so-agree, we would be most happy to discuss this with you at any time. ` Respectfully submitted, WBM:bw Enclosures ' cc: Mr. Edward Gierok William B. Millberg, M.D.,F.C.C.P. - > 'f \ i f ' !l` ROCK 0006696 REPORT TO NORTH AMERICAN ROCKWELL BRAKE DIVISION, ASHTABULA, OHIO CONCERNING THE PULMONARY FUNCTION EVALUATION . OF THOSE EMPLOYEES EXPOSED TU ASBESTOS The purpose of this study was to detect any clinical, radiological, or physiological effects of asbestos exposure upon the work force of North American Rockwell Brake, Division, Ashtabula, Ohio. The basic parameters of this study comply with the recommendations of the National Institute for Occupational Safety and Health of the United States Department of Health, Education and Welfare for the occupational exposure to asbestos. Although the basic recommended criteria were followed, the present evaluation was expanded and investigated in far greater detail. Each individual was evaluated from three diagnostic approaches which consisted of clinical evaluation, radiological examination and physio logical pulmonary function testing. To maintain consistency throughout the study and eliminate individual variations, only one technician was involved in the actual performance of the pulmonary function testing and interpretation of the physiological data was accomplished by one physician. All radiological examinations were taken by two technicians. To eliminate problems of radio logical film processing, films were automatically processed by a Kodak RP X-omat Processor. All films were interpreted by one physician. The quali fications of the physician interpreting the' radiological, physiological, and clinical data include Diplomat of the Board of Thoracic Surgery, Fellowship in the American College of Chest Physicians and membership in the American Thoracic Society. ROCK 0006697 CLINICAL EVALUATION Clinical evaluation consisted of a review of the individuals past medical history, a systemic review, a review of industrial exposures, and an appraisal of smoking habits. Emphasis was placed on cardiopulmonary problems in the past or present respiratory symptoms. "The Questionnaire on Respiratory Symptoms", approved by the British Medical Research Councils Committee on research into chronic bronchitis and considered the world wide standard was basically followed. A physical examination was then conducted with special emphasis placed on the cardio-respiratory symptoms. Two specific parameters were thoroughly evaluated and consisted of evaluation of pulmonary basilar rales and digital clubbing. . -radiological evaluation Radiological evaluation consisted of three separate 14 x 17 teleoroentgenograms. A PA teleoroentgenogram taken in maximal inspiration, a PA teleoroentgenogram taken in maximal expiration and a left lateral teleo roentgenogram taken in maximal inspiration were performed on each individual, High quality DuPont Cronex 4 film was used throughout and films were auto matically processed utilizing the Kodak RP X-omat Processor. The three views were selected since an early manifestation of asbestosis is limita tion of costal and diaphragmatic excursion. The three views also manifest far better correlation with pulmonary function testing. ROCK 0006698 PHYSIOLOGICAL PULMONARY FUNCTION EVALUATION Physiological pulmonary function evaluation consisted of determi nation of total lung capacity and the subdivisions. .Forced, timed, inspiratory and expiratory volumes were performed. Maximal voluntary ventilation and oxygen consumption were evaluated. All studies were performed on a Godart Pulmonet, type 59004, to which was attached a Cardiopulmonary Instruments Corporation Flow-volume digitizer. Model 541 and a C.P.I. Norm Calculator, Model 550. Total lung capacity was determined by the Godart spirometer gas analyzer. The spirometer is a water sealed spirometer with a capacity of nine liters. The brass spirometer bell is lightweight (0.1 mm. thickness) and balanced so that the subject breathes at an absolute zero pressure point. A constant flow of homogeneous gas mixture is provided within the circuit. A two speed recording Kymograph, operating at 60 and 1200 mm. per minute, provides a permanent record. Digital display of volume and flow is provided by the flow volume digitizer. . The functional residual capacity was determined by the closed system helium determination technique utilizing a thermo conductivity gas analyzer for helium. Forced inspiration and expiration volumes were determined both graphically and by digital display on the flow volume digitizer. Maximal voluntary ventilation was determined both graphically and by digital display, using the flow volume flow volume digitizer and the spirometer. ROCK 0006699 All paremeters of the physiological evaluation were repeated at least three times and the best observed value was recorded. Each individual was assumed free.of recent upper respiratory tract infection and if such existed, the test was postponed. The timed spirographic tracing was evalu ated and all observed data was compared with predicted values. The predicted values used were those of the V. A. Cooperative study, the Oregon Thoracic study, DuBois Body Surface chart and the normal values for pulmonary function testing of Bates and Christie and the predicted maximal breathing capacity of Baldwin et al. Guidelines for the interpretation of the physiological data were fundamentally expressed as follows: -- Vital capacity 80 - 90% 60 - 80% 40 - 60% Less than 40% Slight reduction Moderate reduction Marked reduction Very marked reduction Increase In Residual Volume' 125 - 175% 175 - 250% Above 250% Moderate increase Marked increase Very marked increase Decrease In Residual Volume 60 - 80% of preducted 40 - 60% of predicted Below 40% of predicted Moderate decrease Marked decrease Very marked decrease Ratio of Residual Air To Total Lung Capacity 35 - 50 Above 50 Above 65 Moderate degree-of emphysema Severe degree of emphysema Very severe degree of emphysema Maximal Voluntary Ventilation 80 .60 40 Less 95% 80% 60% than 40% Slight decrease Moderate decrease Marked decrease Very marked decrease ROCK 0006700 Impairment. Of Pulmonary Mixing 2-2 1/2 minutes 2 1/2 - 3 minutes . 3-4 1/2 minutes 4 1/2 minutes or more FEV/FEV FEV/FEV FEV/FEV 0.5 sec. 1 sec. 3 sec. Slight decrease Moderate decrease Severe decrease Very severe decrease NORMAL 50 - 55% 80 - 85% 97 - 100% ROCK 0006701 DISCUSSION Asbestos is*a generic term applied to the naturally occurring hydrated mineral silicates incombustible in air and separable into filaments. The particulate matter in asbestos dust is composed of broken fibers of crystalline magnesium silicate containing traces of iron, nickel,, calcium and aluminum. The workers of North American Rockwell Brake Division are exposed to chrysotile, a fibrous form of serpentine. The extent of this exposure is unknown to this examiner, but has been measured and is appar ently extremely low and effectively controlled. Pulmonary asbestosis is an occupational disease which can effect any person working in a factory or industry dealing with asbestos or its products, or living in the vicinity of such an establishment. The develop ment of asbestos depends upon the degree of exposure and the duration of exposure. The asbestos fibers apparently cause mechanical irritation in the terminal and respiratory bronchioles initially surrounded by a gela tinous precipitated protein and resulting in both parenchymal and pleural fibrosis-. * Far advanced pulmonary asbestosis results in profound cardio respiratory, insufficiency, disability and failure. An increased incidence of bronchogenic and gastrointestinal carcinoma appears present. An in creased incidence of pleural mesothelioma is also noted. There appears to be*a synergistic effect between cigaret smoking and exposure to asbestos, with an increased incidence of neoplasis resulting. ROCK 0006702 The most common symptom is dyspnea and clinical evaluation suggests pulmonary insufficiency with basilar pulmonary rales, distant breath sounds, and limitation of respiratory excursion with finger clubbing. The roentgenographic appearance of asijfcstosi's is that of interstitial fibrosis and pleural thickening. An early sign is limitation of costal and diaphragmatic excursion. The pulmonary function derangement is that of restrictive disease with a decrease in vital capacity and residual volume. The most sensitive index appears to be the diffusing capacity of the lung and this parameter is the earliest affected. Correlation between x-ray and pulmonary function studies is poor. The x-ray may be abnormal and the pul monary function study normal. The converse is also true. A definite diagnosis of asbestosis cannot be established in any of the cases reviewed, as this would necessitate histological confirmation. The most prevalent finding was that of chronic bronchitis, which can be attributed to the general environment and the smoking habits of the employees. Since there appears to be a synergistic carcinogenic effect between asbestos exposure and cigaret smoking, an effect should be extended to encourage the workers to cease the practice of cigaret smoking. ' As' can be determined from1 the tables,- incidental disease was encoun tered, which included hypertension, hepatomegaly, inguinal hernia, pulmonary granuloma (proven), and cervical and prescalene lymphadenopathy. Findings suggestive of pulmonary asbestosis were not encountered in any individual studied. ROCK 0006703 NEW RECOMMENDATIONS After thorough review of this study, the following recommendations are suggested to North American .Rockwell Brake Division in Ashtabula, Ohio. 1. An educational campaign be instituted to decrease the incidence of cigaret smoking. 2. Encourage the use of respirators in those exposed to asbestos. 3. Reevaluate each individual on a yearly basis. More meaningful information would be obtained by comparing the individual with his own baseline values than by comparision with predicted normal values. Early detection of abnormality would result and correction could be made. ' 4. Each parameter of the medical evaluation program is considered important if the goal of early detection of abnormality is paramount. Detection of far advanced lung disease at an uncontrollable stage would serve no useful preventative purpose. Because of this, a comprehensive, rather than a cursory evaluation was utilized. . . Clinical evaluation through correlation of the past medical history, industrial exposure and physiological examination aid in the detection of not only chronic lung disease, but other coexisting abnormalities. Radiological evaluation correlated with the clinical picture increases the accuracy of detection of early disease and the three separate roentgenographic studies are considered paramount to this approach. Physiological pulmonary function testing correlated with both the clinical and radiological pictures again enhances the accuracy of early detection of abnormality. The parameters of this physiological testing were selected as those being most affected by early abnormality. In addition to the basic parameters now being evaluated, It is.strongly recommended that pulmonary diffusion studies be included. ROCK 0006704 This is be-ing recommended since abnormality in diffusion appears to be the earliest function to be affected by asbestos pneumoconiosis. Since chronic lung disease is such a prevalent abnormality throughput the United States with its end stage resulting in crippling disability, which for the most part is irreversible, detection and reversal of the early stage is a most significant preventative measure. It is felt that this recommended approach will satify the requirements and will offer an exceptional medical surveilance program to the employees of North American Rockwell Brake Division of Ashtabula, Ohio. ROCK 0006705 NORTH AMERICAN ROCKWELL - PULMONARY FUNCTION 1973 X-RAY NO. AGE 1. 7770 27 2. 7545 26 3. 7753 26 4. 3218 29 5. 7576 30 6. 7603 22 7. 7672 26 8. 8124 23 9. 7577 25 10. 7487 29 11. 7587 21 12. 7636 35 13. 7579 33 14. 928 30 15. 7447 39 16. 8508 30 17. 7568 29 18. 7616 39 19. 7504 30 20. 7635 44 21. 307 41 22. 7481 ' 50 23. 7168 29 24. 7743 33 25. 7970 42 26. 1764 57 27. 7617 35 28. 7050 27 29. 8290 25 30. 7560 30 SEX X-RAY NO. M ' 31'. 7644 M 32. 7700 N 33. 7716 M 34. 7512 M 35. 7566 M 36. 7720 M 37. 7775 M 38. 5523 M 39. 7495 M 40. 7426 M 41. 7778 M 42. 7599 M 43. 7626 M 44. 7642 M 45. 7698 M .46. 7633 M 47. 7561 M 4B. 7779 M 49. 7996 M 50. 7554 M 51. 5371 M 52. 7513 M ,53. 7655 M 54. 7480 M 55. ' 7476 M' 56. 4411 M 57. 7556 M 58. 7622 M 59. 7503 M 60. 2127 AGE 29 35 49 49 52 42 32 31 20 49 43 38 42 20 28 45 ~2837 30 -38 43 33 32 55 33 41 27 42 54 32 SEX M M M M M M M M M M M M M M M M M M H M M M M M M M M M M M ROCK 0006706 TYPE OF WORK . LENGTH OF EXPERIENCE 1. Machine operator - riveter 2. Machine operator 3. Assembly 4. Assembly . 5. Machine operator - .. 6. Riveter " 7. Grinder 8. Grinder . 9. Grinder 10. Machine operator 11. Riveter 12. Paint line 13. Machine operator 14.- Grinder * 15. Grinder 16. Riveter 17. Grinder 18. Riveter 19. ? 20. Assembly 21. Assembly 22. ? ' ' 23. - Grinder 24. Grinder ~ ' 25. Machine operator 26. Assembly 27. Assembly 28. Riveter 29. Riveter 30. Paint line - grinder 31. Assembly 32. Riveter 33. Machine operator 34. ? 35. Riveter 36. Assembly 37. Riveter 38. Riveter 39. ? 40. . ? 41. Shift supertendent 42. Paint line 43. Machine operator 44. Machine operator 45. Grinder . 3 years 20 months . 2 years 71/2 years 1 1/2 years 1 1/2 years 6 years 1 1/2 years 4 years ' ? 1 1/2 years 5 years 11 years 7 1/2 years 6 weeks 1 1/2 years 9 years 9 years ? ' 10 years 6 years ?-- 6 1/2 years 7 1/2 years 4 years 8 1/2 years 10 years 1 year 1 year 8 months 7 1/2 years 1 1/2 years 7 1/2 years 11 years ? 7 years 1 1/2 years 2 months 61/2 years ? ? 25 years 10 years 6 years 2 years 3 months ROCK 0006707 TYPE OF WORK LENGTH OF EXPERIENCE 46. Milling machine - grinder 47. Grinder 48. Machine operator - grinder 49. Riveter 50. Machine operator .' ' *' ' .... 51. Lift operator 52. ? 53. Grinder 54. ? 55. 7 56. Machine operator 57. Grinder 58. Foreman 59. 7 . 60. ? . 25 years . 6 years 8 years 2 years 10 years 6 1/2 years ? 1 month ? ? 3 years 8 years 71/2 years ? ? ROCK 0006708 RESPIRATOR 1. No 2. No 3. No 4. No 5. No 6. No 7. No a. Yes 9. No 10. No n. Yes 12. No 13. No 14. Yes IS. Yes 16. No 17. ? 18. No 19. No 20. No 21. Yes 22. No 23. No 24. No 25. No 26. No 27. No 28. No 29. No 30. No CIGARETTE SMOKER RESPIRATOR No Yes 1/day Yes . 1/day 7 years Yes 1/day 15 years No ' . No - Yes 2/day 13 years . No ' No No No Pipe No Pipe No Yes 2/day 12 years Yes 1 1/2 day 20 years Yes 1 1/2-2/day 15 years ? No Cigar . No Yes 1/day No Yes 2/day Yes^ 1/2/day 10 years Yes 1/day 15 years Yes ' 1/day 30 years Yes 1 1/2/day 40 years No Cigar Yes 1-2/day 7 years Yes 1/day 10 years Yes (quit 1 year ago) 31. No 32. No 33. No 34. ? 35. Yes 36. No 37. Yes 3B; No 39. No 40. ? 41. No 42. No 43. No 44. No 45. Yes 46. No 47. Yes 48. No 49. Yes 50. No 51. No 52. No 53. Yes 54. No 55. No 56. No 57. No 58. No 59. No 60. No CIGARETTE SMOKER No Yes 1 1/2 day 20 years Yes 1/day 25--30 years Yes 1/day Non smoker Yes 1/day 22 years Yes 1/day ? Yes 1-1 1/2/day 7 No No . Yes 1/2/day No No (quit) No Yes 1/day Yes 1 1/2/day 20 years No Yes 1-2/day Yes 1/day No Yes 2/day 20 years Yes 1-1 1/2/day ? No (quit 3 years-ago) Yes 1/day Cigar Yes 1 1/2/day ? ROCK 0006709 PAST MEDICAL HISTORY 1. 2. 3. ' 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15. 16. 17. 18. 19. 20. 21. 22. 23. 24. 25. 26. 27. 28. 29. 30. 31. 32. 33. 34. 35. 36. 37. 38. 39. 40. 41. 42. 43. 44. 45. Negative Negative Allergy Negative Pneumonia, age 16 Negative Negative Negative Negative ' Negative Negative , Pneumonia, age 27 Negative Mild asthma Negative Negative Pneumonia, child Negative Negative Hiatal hernia, gall bladder Pneumonia, age 33 Negative Negative Negative ` Negative Pleural effusion, 40 years ago Pneumonia, age 12 Negative^ Negative Negative Negative Negative Pleurisy, age 29 Negative - Negative Negative Negative Spontaneous pneumothorax, age 27 Negative Negative Pneumonia, child Negative Negative Allergic asthma Carcinoma, testes ' SYSTEMIC REVIEW Negative Negative Negative Negative Negative Negative Productive cough Negative Negative Negative _ Negative Negative Negative Negative Negative Negative Negative Negative Negative . Negative Chest pain Chronic productive cough Negative Negative . Chronic cough Negative Negative Negative Mild cough Negative Negative Negative Negative Negative Minimal cough Negative Negative Negative Negative Negative Negative Negative Negative Negative Negative ROCK 0006710 PAST MEDICAL HISTORY 46. Negative 47. Negative 48. Pneumonia, child 49. Negative 50. Negative 51. No chest disease 52. Negative 53. Negative 54. Negative 55. Negative 56. Negative 57. Negative 58. Negative 59. Negative . 60. Negative SYSTEMIC REVIEW Negative Negative Negative Negative Negative Negative Negative Negative Cough, dyspnea Negative Negative Negative Negative Negative Negative ROCK 0006711 PHYSICAL EXAMINATION 1. Normal 31. Normal 2. Normal 32. Chronic otitis media 3. Normal 33. Normal, chest scar 4. Normal 34. Normal 5. Normal 35. Left prescalene nodes 6. Normal * 36. Normal 7. Normal 37. Normal 8. Inguinal hernia, right 38. Normal 9. Normal 39. Normal * 10. Normal 40. Normal 11. Normal 41. Normal 12. Normal 42. Normal 13. Normal 43. Normal 14. Normal 44. Normal ' 15. Normal 45. Absent right testes, old scar 16. Normal 46. Normal 17. Normal 47. Normal, left inguinal hernia 18. Normal 48. Normal, cough 19. Normal 49. Normal 20. Normal 50. Normal 21. Normal 51. 'Normal 22. Normal 52. Normal -- 23. Normal - 53. Normal 24. Normal 54. Normal 25. Normal 55. Normal 26. Normal, with questionable liver and 56. Normal increased blood pressure 57. Normal 27. Normal 58. Undescended left testes 28. Normal 59. Occasional extrasystoles 29. Normal, cough ' 60. Normal 30. Normal ROCK 0006712 CHEST X-RAY 1. Normal 2. Residuals of remote disease, no active disease. . 3. Normal .. 4. Basilar fibrosis 5. Normal 6. Normal 7. Normal 8. Minimal bronchitis 9. Normal 10. Normal 11. Normal 12. Normal 13. Normal 14. Minimal bronchitis 15. Normal ' 16. Normal, bifed rib 17. Normal 18. Normal 19. Minimal pulmonary fibrosis ` 20. Normal 21. Chronic bronchitis, minimal fibrosis- 22. Normal . 23. Normal 24. Residuals of remote disease 25. Normal 26. Pulmonary fibrosis, minimal 27. Normal 28. Normal 29. Normal . 30. Normal ' 31. 32. 33. 34. 35. 36. 37. 38. 39. 40. 41. 42. 43. 44. 45. 46. 47. 48. 49. 50. 51. 52. 53.54. 55. '56. 57. 58. 59. 60. Normal Minimal fibrosis Pulmonary fibrosis Normal . Questionable hilar mass, fibrosis Minimal fibrosis Normal Normal . Normal Minimal fibrosis . Normal . Normal Normal Normal Normal Wide retrosternal air space Normal Normal Normal Normal Normal Normal Chronic bronchitis Solitary node (proven granuloma) Normal Normal Normal * Normal Widened retrosternal air space Normal ROCK 0006713 TOTAL LUNG CAPACITY 1. Normal 2. Normal 3. Normal 4. Normal 5. Normal 6. Normal 7. Normal 8. Normal 9. Normal IQ. Normal n. Slight decrease 12. Normal 13. Normal 14. Normal 15. Normal 16. Normal 17. Normal 18. Normal 19. Normal 20. Slight decrease 21. Normal 22. SIight decrease 23. Normal 24. Normal 25. Normal 26. . Slight decrease 27. Normal 28. Normal 29. Slight decrease 30. Normal 31. SIight decrease 32. Normal 33. Moderate decrease 34. Normal 35. Normal 36. Normal 37. Normal 38. Normal 39. Slight decrease 40. Slight decrease 41. Normal 42. Normal 43. Normal 44. Normal 45. Normal PULMONARY FUNCTION VITAL CAPACITY RESIDUAL VOLUME Normal Normal . Normal ' Slight decrease ' Normal Normal ' Normal Slight decrease Slight decrease Slight decrease Moderate decrease Normal Slight decrease Normal Normal ' Normal Normal Normal Normal Moderate decrease Normal Slight decrease Normal Normal Normal Slight decrease Normal Normal Slight decrease Normal Slight decrease Normal Moderate decrease Normal .Normal Normal ' Normal Normal Slight decrease Moderate decrease Normal Normal Normal Normal Normal . Normal Normal . Moderate increase Normal ` Normal Normal Normal Normal Normal Normal Moderate decrease Moderate increase Normal Normal Slight increase Slight decrease Normal Normal Normal Normal Moderate Increase Normal Slight decrease Slight increase Normal Normal Slight decrease Normal Moderate decrease Normal Slight decrease Normal Moderate decrease Normal Normal Normal ' Normal Slight decrease Slight decrease Normal Slight decrease Normal Normal Normal Slight increase ROCK 0006714 TOTAL LUNG CAPACITY 46. Normal 47. Normal 48. Normal 49. Normal 50. Normal 51. Normal 52. Normal 53. Normal 54. ' Normal 55. Normal 56. Normal 57. Normal 5B. Normal 59. Normal 60. Normal ' PULMONARY FUNCTION VITAL'CAPACITY Normal Normal Normal Normal Slight decrease Slight decrease Normal ' Normal Normal Normal Normal Normal Normal Moderate decrease Normal RESIDUAL VOLUME Normal Slight increase Normal Normal Normal Moderate increase Normal Moderate increase Moderate increase Normal Slight increase Normal Slight decrease Slight increase Normal ROCK 0006715 FORCED EXPIRATORY VOLUME 1. Normal 2. Normal 3. Norma 1 4. Slight decrease 5. Normal 6. Normal 7, Normal . 8. Slight decrease 9. Norma 1 10. Normal 11. Slight decrease 12. Normal 13. Slight decrease 14. Slight decrease 15. Normal . 16. Normal 17. Normal 18. Normal 19. Normal 20. Moderate decrease 21. Normal 22. Normal 23. Normal 24. Slight decrease 25. Normal . 26. Slight decrease 27. Normal 28. Slight decrease 29. Slight decrease 30. Normal '31. Normal * 32. Normal 33. Slight decrease 34. Normal 35. Normal 36. Normal 37. Normal 38. Normal 39. Normal . 40. Normal MAXIMAL VOLUNTARY VENTILATION Normal Normal Normal Slight decrease Norma) Normal Slight decrease Normal Normal Normal Normal Normal Slight decrease Slight decrease Slight decrease Normal Normal Slight decrease Normal Normal Normal Normal Normal Slight decrease Normal Slight decrease Slight decrease Normal Slight decrease Normal Normal Normal Normal Normal Normal Normal Normal Normal Normal Normal ROCK 0006716 FORCED EXPIRATORY VOLUME MAXIMAL VOLUNTARY VENTILATION 41. Normal 42. Normal . 43. Normal 44. Normal .. - * ' 45. Normal 46. Normal ' 47. Normal 48. Slight decrease 49. Normal 50. Normal 51. Slight decrease '. 52. Normal , 53. Normal ' ' 54. Normal 55. Normal ' 56. Normal . 57. Normal 58. Normal ' 59. Normal 60. Normal Normal Slight decrease Slight decrease Moderate decrease Moderate decrease Normal Normal Slight decrease Normal Slight decrease Slight decrease Normal ' Slight decrease Normal ~~ Slight decrease Normal Slight decrease Normal Normal Slight decrease ROCK 0006717 CONCLUSION OF STUDY 1. Normal 2. Normal 3. , Minimal degree of obstruction Bronchial disease - 4. Minimal chronic bronchitis 5. Normal 6. Normal 7. Normal 8. Normal. Inguinal hernia 9. Normal 10. Normal 11. Slight bronchitis 12. Minimal bronchitis 13. Normal 14. Minimal chronic bronchitis 15. Normal 16. Normal 17. Normal 18. Normal 19. Normal 20. Moderate restrictive disease 21. Normal. Slight increase of respiratory volume 22. Minimal bronchitis 23. Normal 24. Minimal chronic bronchitis 25. Normal 26. Slight restrictive disease, bronchitis 27. Normal 28. Normal 29. Chronic bronchitis 30. Normal 31. Normal 32. Normal 33. Slight restrictive disease, old trauma 34. Normal 35. Abnormal physical and x-ray exam. 36. Normal 37. Normal 38. Normal 39. Chronic bronchitis 40. Minimal destructive disease . 41. 42. 43. 44. 45. 46. 47. 48. 49. 50. 51. 52. 53. 54. 55. 56. 57. 58. 59. 60. Slight bronchitis Normal . Minimal chronic bronchitis Slight obstructive disease Normal. History of cancer, testes Normal Normal Chronic bronchitis. Normal Normal Bronchitis Normal Chronic bronchitis. Questionable early emphysema. Early emphysema. Granuloma Normal Normal Normal Normal Early emphysema Normal ROCK 0006718 NURTH AMERICAN ROCKWELL - PULMONARY FUNCTION 1973 X-RAY NO. 1. 7770 2. 7545 3. 7753 4. 3218 5. 7576 6. 7603 7. 7672 8. 8124 9. 7577 10. 7487 11. 7587 12. 7636 13. 7579 14. 928 15. 7447 16. 8508 17. 7568 18. 7616 19. 7504 20. 7635 21. 307 22. 7481 23. 7168 24. 7743 25. 7970 26. 1764 27. 7617 28. 7050 29. 8290 30. 7560 AGE SEX 27 31*. 26 32. 26 [4 G. 33. 29 30 M m.eA*JuL2*"35. 22 36. 26 M 37. 23 38. 25 M nv c-.-fajJv-' 39. 29 M . 40. 21 M-n.Q>A&u^=41. 35 M jujJJ-- 42. 33 M iQ- 43. 30 M 44. 39 45. 3Q 29 M47. 39 M Q-* iluA'Oi*-''" 48. 30 M ' 49. 44 - f*j Q_ 50. 41 M 0.. 51. 50 52. 29 M .53. 33 54. 42 57 M 56. 35 ' 57. 27 M UJ- t10f:C9imft<rwo 58. 25 59. 30 M^.moEcxJLi 60. X-RAY NO. - AGE SEX 7644 7700 7716 7512' 7566 7720 7775 5523 7495 7426 7778 7599 7626 7642 7698 7633 7561 7779 7996 ` 7554 5371 7513 7655 7480 7476 4411 . 7556 7622 .7503 2127 29 35 49 49 ' 52 42 32 31 20 49 43 ' - 38 42 20 28 45 28 37 30 38 43 33 32 55 33 41 * 27 42 54 32 M a. M rrvajLo^ M ijj. M JVJ ft. HC.Pja^ f*J O, RXc^ M M ' Z- M rn . Rf-c^fi-- M M > M OL. S-r-oTi-K MB M R* M ^ ivyuJjA' M C . *y%jLV4AyUrtxXJ M Q. M" --C*J * M &. i^ 1''A'~ 0 n n M 0- * xJUao-v M ft. UJA^fcM M i i I ROCK 0006719