Document NEb1G14BQpwjZNpvMrvBaEOmg

Subject: CONFIDENTIAL Resu|ts of Animal Studies at I.R.D.C. MMaayy I100,, 11997788 THOSE PRESENT: R. J. DAVIS L. C. KROGH JJ.. DD.. LLAAZZEERRTTEE T3a4mresrs a R. A. NELSON J. A. PENDERGRASS R. A. PROKOP T. J. SCHEUERMAN F. A. ~BE[ 220-12E 223-6SE 223366--I1 gB2f2 218-3 220-2E(/~ 236-3B~ 220-2E~) ZzO-zL TThhoossee pprreesseenntt mmeett on May 8, 1I9g78 to discuss results of the 90 day aanniimmaall ssttuuddiieess ccaarrrriieedd oouutt aatt IInntteerrnnaattiioonnaall Research and Develop- borane a ete marerone esr td Bevelop ment Corporation. The dosing phase of the studies on rats using FC-95, FM-3422 and FC-143 have been completed. Results indicate Rass THESFE he den com that FC-95, FM-3422 and FC-143 are toxic. Aero review of the data and a veview of te arch 1, 197 EPA After a review of the data and a review of the March 16, 1978 EPA gguuiiddeelliinneess ffoorr rreeppoorrttiinngg ssuubbssttaannttiiaall rriisskk under the Toxic Substances Control Act, it was decided that the toxicity of FC-95, FM-3422 and FC-143 does not constitute a substantial risk and should not be reported at this time. 2 48 Aap ot RAP:df 11117722..00000011 Exhibit 172 33MMAA1100006666996611