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1 SI - CA/096/109339A CC - CA/159002 AU - Kannan S ; Shah JA { Srinivasan D AD - Dep. Chem. Eng. A. C. Coll. Technol. Madras TI - An environmental assessment of the manufacturing processes of polyCvinyl chloride) SO - Indian Chem. Manuf.5 VOL 19, ISS 9, 1981,4-8, 2 plates PT - JOURNAL ARTICLE CY - India ZP - 600 025 LA - ENG CD - ICMFA IS - 0367-7257 AB - CBAC COPYRIGHT! CHEM ABS PVC manufg air pollution controljAir pollution Control of, PVC manufg. processes in relation to{Environment Of PVC manufg. processes, assessment of RN - 75-01-4*, 9002-86-2 EM - 8205
2 SI - CA/096/109303J CC - CA/159001 AU - Kaneko Y AD - Nippon 6en. Trading Co. TI - High sensitive photoionization detector gas chromatography for direct gas analysis SO - Nenryo oyobi Nensho; VOL 48, ISS 11, 1981,829-36 PT - JOURNAL ARTICLE CY - Japan LA - JPN CD - NEONA IS - 0369-3783 AB - CBAC COPYRIGHT: CHEM ABS Gas chromatograph air analysis Photoionization detector gas chromatograph air;Air analysis Photoionization-detector gas chromatograph in{Chromatography Photoionization detector in, for air anal. Gas RN - 64-17-55 71-43-2J 75-01-4; 80-56-8*, 7783-06-4', 7784-42-1; 7803-51-2 EM - 8205
3 SI - CA/096/109268B CC - CA/159000 AU - Popper H ; Selikoff IJ AD - Mt. Sinai Sch. Med., City Univ. New York, New York TI - Classical syndromes in occupational medicine. Pathological lessons from vinyl chloride angiosarcoma SO - Am. J. Ind. Med.; VOL 2, ISS 2, 1981,187-96 PT - JOURNAL ARTICLE CY - USA ZP - 10029 LA - ENG CD - AJIMD IS - 0271-3586
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AB - CBAC COPYRIGHT: CHEM ABS Review vinyl chloride disease exposure Occupational exposure vinyl chloride revieu;Health hazard From
occupational exposure to vinyl chloride* angiosarcoma in relation toJSarcoma From vinyl chloride exposure* industrial hygiene in relation to AngioRN - 75-01-4 EM - 8205
4 SI - CA/096/080938G CC - CA/104003 AU - Desyatr.' kova NN TI - Change in blood lipidsduring chronicvinyl chloride intoxication SO - Aktuai'n. Vopr. Gigieny Truda i Profpatol. v Nekotor. Otraslyakh Khim. Prom-sti i na Avtomob. Transp* 1981*98-100 PT - JOURNAL ARTICLE CY - USSR LA - RUS CD - D3RAP AB - CBAC COPYRIGHT: CHEM ABS Title only translated. Vinyl chloride toxicity blood lipid RN - 75-01-4 EM - 8204
5 SI - CA/096/080781A CC - CA/104000 AU - Sharma RP AD - Utah State Univ. Logan TI - Industrial compounds and modification of immune responses: studies with vinyl chloride SO - Immunol. Consid. Toxicol.* VOL 1>* 1981*79-88 PT - MONOGRAPH CY - USA LA - ENG CD - 47AWA AB - CBAC COPYRIGHT*. CHEM ABS A review with 17 refs, on the immunol. responses to vinyl chloride [75-01-4] and other industrial chems. RN - 75-01-4 EM - 8204
6 SI - CA/096/063759G CC - CA/104001 AU - Madlo Z ; Kubiskova B * Svobodova P > Simova M AD - Krajska Hyg. Stanice* SKNV* Prague TI - Determination of the vinyl chloride metabolite S-(2-hydroxyethyl )-N-acetylcysteine in urine SO - Prac. Lek.J VOL 33, ISS 9, 1981,319-23 PT - JOURNAL ARTICLE CY - Czech. LA - CZE CD - PRLFA IS - 0032-6291 AB - CBAC COPYRIGHT: CHEM ABS S-(2-hydroxyethyl)-N-acetylcysteine (I) C15060-26-1] was detd. spectrophotometrically in urine.
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Amphoteric interfering compds. were removed prior to the anal, via chromatog. on Dowex 50 W. Nonamphoteric interfering compds. were removed by hydrolysing I to S-(2-hydroxyethyl )cysteine and sepg. this hydrolysis product by chromatog. on Dowex 50 W. After elution the S-(2-hydroxyethyl)cysteine was reacetylated, hydrolysed, and the SH compds. analysed. The technique afforded reproducible results and gave yields of 74.7-81.3/J. The method is useful as a test for exposure to vinyl chloride C75-01-4] and other alkylation compds. metabolized to mercapturic acids. RN - 75-01-4} 15060-26-1 EM - 8204
7 SI - CA/096/090762J CC - CA/159000 AU - Bauer U AD - Inst. Hyg. Ruhr-Univ. Bochum Bochum TI - Human exposure to environmental chemicals - studies on volatile organic halogenated compounds in water* air* food* and human tissues. III. Results of studies SO - Zentralbl. Bakteriol.* Mikrobiol. Hyg.* Abt. 1* Orig. B> VOL 174* ISS 3, 1981,200-37 PT - JOURNAL ARTICLE CY - Fed. Rep. Ger. ZP - D-4630/1 LA - GER CD - ZAOMD AB - CBAC COPYRIGHT: CHEM ABS Review org halogen exposure environment;Air pollution By volatile org. halogenated compds., human exposure injAnimal tissue Volatile org. halogenated compds. in* human exposure in relation to Human;Environment Volatile org. halogenated compds. in, human exposure tojFood Volatile org. halogenated compds. in* human exposure to50rganic compounds In environment* human exposure to Halo;Water pollution By volatile org. halogenated compds., human exposure in RN - 56-23-5; 67-66-3J 67-72-1; 71-55-6*, 75-01-4; 75-09-2; 75-25-2; 75-27-4; 76-01-7; 79-00-5; 79-01-6*, 79-34-5; 87-61-6*, 87-68-3J 95-50-1; 95-73-8*, 96-18-4*, 99-99-0; 106-93-4*, 107-06-2; 108-70-35 124-48-15 127-18-45 142-28-9; 541-73-15 630-20-6 EM - 8204
8 SI - CA/096/074411P CC - CA/161005 AU - Anon TI - The central plant of the St. Louis County Water Company SO - Aqua (London); ISS 4, 1981,20-4 PT - JOURNAL ARTICLE CY - USA LA - ENG CD - AQUAA IS - 0003-7214 AB - CBAC COPYRIGHT: CHEM ABS Drinking water plant Saint Louis5Alkalinity Of wastewater treatment plant effluent, at St. Louis County, MissouriJBacteria Water treatment plant effluent
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contg.* at Saint Louis county* Missouri Chloroform;Chlorides Mater treatment plant effluent contg.* at Saint Louis county* Missouri{Color Of wastewater treatment plant effluent* at St. Louis County* MissouriJCyanides Waste treatment plant effluent contg.* at St. Louis County* MissouriSFluorides Water treatment plant effluent contg.* at Saint Louis county. MissourijFluorides Water treatment by* at Saint Louis county, MissourijFoaming agents Water treatment plant effluent contg.* at St. Louis County* MissourijNitrates Water treatment plant effluent contg., at Saint Louis county, MissourijNitrites Water treatment plant effluent contg., at Saint Louis county, MissourijOrder Of wastewater treatment plant effluent, at St. Louis County, Missouri{Polymers Water treatment by* at Saint Louis county* Mi ssouriJSulfates Water treatment plant effluent contg., at Saint Louis county, Missouri{Water purification Plant for, at Saint Louis county* Missouri, chem. compn. of effluent fromjWaters Plant for suppling, at Saint Louis county, Missouri Potable* drinking RN - 56-23-5* 58-89-9} 71-43-2} 71-55-6} 72-20-8J 72-43-5} 74-83-9} 74-87-35 75-00-3} 75-01-4} 75-34-3} 75-35-4} 75-69-4} 78-87-5} 79-00-5} 79-01-65 79-34-5} 92-52-4} 94-75-7} 100-41-4} 107-06-2} 108-88-3} 108-90-75 110-75-85 127-18-4} 156-60-5} 471-34-1} 7439-89-65 7439-92-15 7439-95-4} 7439-96-5} 7439-97-6} 7440-09-7} 7440-22-4} 7440-23-5} 7440-38-2} 7440-39-3} 7440-43-9} 7440-47-35 7440-50-8} 7440-70-25 7631-86-95 7782-49-2} 8001-35-2} 10028-17-8} 10043-66-0} 10045-97-3} 10061-01-5} 10061-02-6} 10098-97-25 12587-46-1} 12587-47-2} 13982-63-3} 14798-08-4} 15262-20-1} 80702-86-9 EM - 8204
9 SI CC AU AO TI SO PT CY LA CD IS AB
RN
CA/096/074120T CA/160003 Hwang ST
U. S. Environ. Prot. Agency* Washington Treatability of toxic wastewater pollutants by solvent extraction AIChE Symp. Ser.} VOL 77, ISS 209, 1981,304-15 JOURNAL ARTICLE USA
ENG ACSSC
0065-6812 CBAC COPYRIGHT: CHEM ABS Toxic pollutant solvent extn wastewater Distribution coeff solvent extn wastewaterJOrganic
compounds Toxic* removal of* from wastewater, distribution coeffs. for{Wastewater treatment Toxic org. compd. removal by*
distribution coeffs. for Extn. 50-29-35 50-32-8} 51-28-5} 56-23-5} 56-55-3} 59-50-7} 62-75-9} 67-66-3} 67-72-1} 71-43-2} 71-55-6} 74-83-9} 74-87-3} 75-00-3} 75-01-4} 75-09-2} 75-25-2} 75-27-4} 75-34-3} 75-35-45 75-69-4} 75-71-8} 76-44-8} 77-47-45 78-59-1} 78-87-55 79-00-5} 79-01-6} 79-34-5} 84-66-25 84-74-2} 85-01-8} 85-68-7} 86-30-6} 86-73-7} 87-68-35 87-86-5} 88-06-2} 88-75-5} 91-20-35 91-58-7} 91-94-1} 92-87-55 95-50-1} 95-57-85 98-95-3} 100-02-7 { 100-41-4} 101-55
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EM
10 SI CC AU AD TI SO
PT CY ZP LA CD AB
RN
EM
11 SI CC AU TI
SO PT CY LA CD IS AB
RN EM
105-67-9} 106-46-75 107-02-8; 107-06-2? 108-88-3? 108-90-75 108-95-2J 110-75-85 111-44-45 in-91-i; 117-81-75 117-84-05 118-74-1; 120-12-75 120-82-1J 120-83-2J 121-14-2J 122-66-7*, 124-48-15 127-18-45 129-00-05 131-11-3; 156-60-55 191-24-2; 205-99-25 206-44-05 207-08-95 208-96-85 218-01-95 534-52-15 541-73-1; 542-75-65 606-20-25 621-64-7} 1024-57-35 7005-72-35 39638-328204
CA/096/073830N CA/159001 Fehsenfeld FC ; Goldan PD 5 Phillips MP ; Sievers RE Aeron. Lab., Natl. Oceanic Atmospheric Adm. Boulder Selective electron-capture sensitisation J. Chromatogr. Libr.5 VOL 20 ISS Electron Capture: Theory Pract. Chromatogr. 1981,69-90 JOURNAL ARTICLE USA 80302 ENG JCLID CBAC COPYRIGHT: CHEM ABS Electron capture detector air analysis
Nitrous oxide electron capture detection Chlorocarbon detn air detector Fluorochlorocarbon detn air detector Vinyl chloride detn air detector;Air analysis By electron capture detection, nitrous oxide effect on 56-23-5; 67-66-35 71-55-65 74-82-8; 74-84-05 74-87-35 74-98-65 75-01-45 75-07-0J 75-09-25 75-45-65 75-71-8J 106-97-8; 109-66-05 110-54-35 124-38-95 127-18-45 463-58-15 593-53-3? 630-08-0? 1320-37-2? 1333-74-0? 10024-97-25 26523-64-8 8204
CA/096/073768Y CA/159000 Tsendrovskaya VA Migration of harmful substances from poly(vinyl chloride )-based building materials Plast. Massy; ISS 11, 1981,46-7 JOURNAL ARTICLE USSR RUS PLMSA 0554-2901 CBAC COPYRIGHT: CHEM ABS Review migration toxin polymer material Vinyl chloride polymer material safety Construction material vinyl chloride migration?Air pollution By vinyl chloride migration from polyvinyl chloride-based building materials?Building materials Polyvinyl chloride-based, vinyl chloride migration from 75-01-45 9002-86-2 8204
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12 SI - CA/096/057412X CC - CA/161002 AU - Page GW AD - Dep. Urban Planning Univ. Wisconsin* Milwaukee TI - Comparison of groundwater and surface water for patterns and levels of contamination by toxic substances SO - Environ. Sci. Technol.5 VOL 15, ISS 12, 1981,1475-81 PT - JOURNAL ARTICLE CY - USA ZP - 53201 LA - ENG CD - ESTHA IS - 0013-936X AB - CBAC COPYRIGHT! CHEM ABS Groundwater surface water pollution comparisonjWater pollution By toxic substances, comparison of ground and surface, on New Jersey RN - 50-29-3J 56-23-55 58-89-9; 60-57-1; 67-66-35 71-55-6; 72-20-85 72-54-85 74-87-35 74-95-35 75-01-45 75-09-25 75-11-65 75-25-25 75-35-45 75-46-75 76-44-85 79-00-55 79-01-65 79-34-55 95-50-15 106-46-7; 106-93-45 107-06-25 124-48-15 156-60-55 309-00-25 319-84-65 319-85-75 541-73-15 789-02-65 1024-57-35 3424-82-65 7439-92-15 7440-02-05 7440-38-25 7440-41-75 7440-43-95 7440-47-35 7440-50-85 7440-66-65 7782-49-25 11097-69-15 12672-29-65 12789-03-65 25321-22-65 53469-21-95 73506-91-9 EM - 8204
13 SI - CA/096/033627V CC - CA/117007 TI - Fish paste kamaboko packaging film SO - Jpn. Tokkyo Koho PATENT NO. 81 35427 08/17/81 (Kureha Chemical Industry Co., Ltd.) PT - PATENT CY - Japan LA - JPN AB - CBAC COPYRIGHT: CHEM ABS Packaging material fish paste Polypropylene packaging fish paste Kamaboko polypropylene packaging;Fish Packaging material for, polypropylene-based Paste, kamabokoJGlycerides Polypropylene packaging material coating with, for fish paste5Packaging materials For fish paste, polypropylene-based RN - 75-01-45 75-35-45 9003-07-05 12441-09-7 EM - 8204
14 SI - CA/096/024063F CC - CA/159001 AU - Pan C 5 Bao J 5 Wang Z AD - Dep. Modern Chem., Chin. Univ. Sci. Technol., Beijing TI - Measurement of vinyl chloride in the atmosphere by gas chromatography SO - Huanjinq Kexue; VOL 2, ISS 5, 1981,325-9 PT - JOURNAL ARTICLE CY - Peop. R..p. China
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LA - CHI CD - HCKHD IS - 0250-3301 AB - CBAC COPYRIGHT: CHEM ABS Vinyl chloride detn gas chromatog}Air
analysis Vinyl chloride detn. in* by gas chromatog. RN - 74-86-2} 75-01-4} 75-07-0 EM - 8204
15 SI - CA/096/029533U CC - CA/104003 AU - Laib RJ } Gwinner LM } Bolt HM AO - Inst. Pharmacol.* Univ. Mainz* Mainz TI - DNA alkylation by vinyl chloride metabolites: etheno derivatives or 7-alkylation of guanine? SO - Chem.-Biol. Interact.} VOL 37, ISS 1-2, 1981,219-31 PT - JOURNAL ARTICLE CY - Fed. Rep. Ger. ZP - D-6500 LA - ENG CD - CBINA IS - 0009-2797 AB - CBAC COPYRIGHT: CHEM ABS When rat liver microsomes, an NADPH-regenerating system, DNA, and 14C-labeled vinyl chloride [75-01-4J were incubated and, when the DNA was subsequently reisolated and (enzymically) hydrolyzed, chromatograms Con Aminex A-6) showed the presence of l,N6-ethenodeoxyadenosine [68498-25-91, 3,N4-ethenodeoxycytidine [68498-26-01, and 7-N-C2-oxoethylIguanine [73100-87-51 [the product of hydrolysis of 7-N-C2-oxoethylIdeoxyguanosinel. By contrast, when rats were exposed to [1,2-14C1vinyl chloride and when the liver DNA of these rats was subjected to similar procedures, no radioactive etheno derivs. could be detected, but a radioactive peak was eluted with 7-N-C2-oxoethyl Iguanine. This peak could be transformed into 7-N-C2-hydroxyethyl Iguanine, the chromatog. behavior of which was identical to the ref. compd. used by Ostermann-Golkar et al. C1977). Thus, the compd. described by these authors, 7-N-C2-oxoethyl Iguanine, is in fact the major product of base alkylation in DNA after exposure to vinyl chloride. RN - 75-01-4} 68498-25-9} 68498-26-0} 73100-87-5 EM - 8202
16 SI - CA/095/225062H AU - Scharein G AD - Chem. Werke Huels A.-G., Marl TI - Recover products from chlorohydrocarbon residues SO - Hydrocarbon Process., Int. Ed.} VOL 60, ISS 9, 1981,193-4 LA - ENG CD - IHPRB AB - CBAC COPYRIGHT: CHEM ABS A recovery plant for residues from the chlorination of ethylene to 1,2-dichloroethane (I) and conversion of I to vinyl chloride consists of a thin film evaporator, a screw app., and a rectifying column. (74-85-1 Ethylene)(107-06-2
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12-Dichloroethane )(75-01-4 Vinyl chloride) The mixed residues (carbon black* tarry polymeric chlorinated compds.> various aliph. and arom. chlorinated compds.) contg. .apprx.80X I and light org. chlorides are 1st evepd. to give a distillate and a pumpable slurry which is thermally decompd. in the screw app. under N at 300-30.degree.. The products are a distillate and an impure carbon black. The distillates are combined and rectified to give I and 1,1,2-trichloroethane. (79-00-5 1,12-Trichloroethane) All solid residues are burnt and HCKdecompn. product) is recirculated. RN - 74-85-1; 107-06-2; 75-01-4? 79-00-5 EM - 8201
17 SI - CA/095/225043C AU - Harrison DW ; Reynolds LF AD - ICI Brixham Lab. Brixham/Devonshire TI - Liquid effluent treatment and disposal at ICI Milhelmshaven site SO - Inst. Chem. Eng. Symp. Ser.5 VOL 67, ISS Ind. Mater Econ., 1981,133-43 LA - ENG CD - ICESD AB - CBAC COPYRIGHT: CHEM ABS The treatments for the effluents from PVC and vinyl chloride monomer manufg. include pH adjustment, ethylene dichloride stripping, metal hydroxide removal, and bio-treatment. RN - 75-01-4J 107-06-2? 9002-86-2 EM - 8201
18 SI - CA/095/ec40661 AU - Budai Z ; Ssejtli J AD - Chi no in Gvogyszer Vegyesseti Termekek Gyara, Budapest TI - Absorption of vapors by cyclodextrin solution SO - Magy. Kern. LapjaJ VOL 36, ISS 4-5, 1981,248-54 LA - HUN CD - MGKLA AB - CBAC COPYRIGHT: CHEM ABS Org. solvents and other volatile compds. are removed from air by alpha- or beta-cyclodextrin aq. soln. by forming cryst. inclusions compds. (10016-20-3 alpha.-Cyclodextrin)(7585-39-9 .beta.-Cyclodextrin ) Expts. carried out with beta-cyclodextrin, beta-cyclodextrin polymer and beta-cyclodextrin-cetyltrimethylammoniurn bromide inclusion compd. (I) showed I to be the most effective. (79647-56-6 .beta.-cyclodextrin polymer) I being unstable releases the cetyltrimethylammoniurn bromide from the beta-cyclodextrin host compd. which in turn will be host to the solvent in its cage structure. (57-09-0 Cetyltrimethylammonium bromide) The beta-cyclodextrin is regenerated by heating to release the solvent. RN - 10016-20-3J 7585-39-9? 79647-56-6? 79631-77-9? 57-09-0? 56-23-5J 64-17-5; 67-56-1? 67-64-1J 67-66-3? 71-23-8? 71-36-3? 71-43-2? 75-01-4? 75-97-8? 78-83-1? 78-93-3? 92-52-4? 95-75-0? 101-84-8? 107-06-2? 108-20-3? 108-88-3? 108-90-7? 110-54-3? 110-82-7? 111-36-4? 123-54-6? 123-86-4? 141-78-6? 541-41-3
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EH - 8201
19 SI - CA/095/224662S AU - Kemka R ; Kollar V AD - Vysk. Ustav Preventivneho Lek. Bratislava TI - Determination of vinyl chloride in atmosphere by means of gas chromatography during sampling on activated carbon SO - Prac. Lek.; VOL 33, ISS 5, 1981,167-70 LA - CZE CD - PRLFA AB - CBAC COPYRIGHT: CHEM ABS A method was developed for the detn. of vinyl chloride in air. (75-01-4 Vinyl chloride) Air samples were passed through an activated C bed at 0.03-0.05 L/min. The adsorbed vinyl chloride was removed by elution with CS2 contg. CC14 as an internal std. Gas chromatog. was used to det. vinyl chloride in air at 53-9506 mg/m3 with a relative error of -3.1 to 2.4X. RN - 75-01-4 EM - 8201
20 SI - CA/095/174622F AU - Slater RC ; Douglas-Hamilton OH AD - Avco Everett Res. Lab., Everett TI - Electron-beam-initiated destruction of low concentrations of vinyl chloride in carrier gases SO - J. Appl. Phys.J VOL 52, ISS 9, 1981,5820-8 LA - ENG CD - JAPIA AB - CBAC COPYRIGHT: CHEM ABS The destruction of ppm levels of vinyl chloride by high-energy electron-beam irradn. was investigated in various host gases. (75-01-4 Vinyl chloride) Measurements of vinyl chloride destruction were detd. over the electron-beam dose range .apprx.0.01-6 Mrad. The high dose results indicate that a factor of 20 redn. in vinyl chloride concn. can be realised for an initial 10 ppm molar vinyl chloride stream in air. A discussion of the kinetic processes responsible for vinyl chloride destruction is presented. RN - 75-01-4 EM - 8201
21 SI - CA/095/174620D AU - Jovicevic S Skenderi S ; Konjevic N AD - Inst. Appl. Phys., Belgrade TI - Spectrophone measurements of air pollutants absorption coefficients at carbon dioxide laser wavelengths. II SO - Spectrosc. Lett.; VOL 14, ISS 6, 1981,415-22 LA - ENG CD - SPLEB AB - CBAC COPYRIGHT: CHEM ABS Laser optoacoustic spectroscopy technique was used to measure the absorption coeffs. of gas pollutants at C02 laser wavelengths of 9.2-10.8 .mu.m. All measurements were performed with pollutant at a low pressure in the presence of 1 atm of N. For outdoor long-optical path
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monitoring of air pollution, pairs of lines (detection and ref. line) have been selected. RN - 67-56-1; 67-63-05 75-00-3; 75-01-45 75-05-85 110-82-7; 141-78-6; 7446-09-5 EM - 6201
22 SI - CA/095/174552H AU - Il'icheva GV ; Kuznetsova LV AD - Gor'k. Nauchno-Issled. Inst. Gig. TrudaProfzabol. Gorkiy TI - Gas chromatographic determination of vinyl chloride in the air SO - Gig. Sanit.; ISS 7, 1981,52-4 LA - RUS CD - 6ISAA AB - CBAC COPYRIGHT: CHEM ABS A method was developed for the detn. of vinyl chloride (I) at 6 .times. 10-4 -0.45 mg/m3 concns. in air. (75-01-4 Vinyl chloride) Air was drawn through activated carbon at lL/min rate for 30 min, the adsorbed I was desorbed by passing 50 mL N at 270.degree, through the carbon during 30s and adsorbing I on silica gel at 0.degree.. The desorption of I from silica gel was done with N carrier gas flowing at 35 L/min into a gas chromatog. column at 50.degree.. The column was 3m long and it was filled with Cellite 545 contg. 152 dinonyl phthalate. The anal, took .ltoreq.10 min; acetylene, ethylene, MeOH, Cl2C:CHCl, C1CH2CH2C1, acetone, and H20 did not interfere. RN - 75-01-4 EM - 8201
23 SI - CA/095/174437Z AU - Walker AE AD - R. Hosp. Chesterfield/Derbyshire TI - Vinyl chloride disorder SO - Br. J. Dermatol.; VOL 105, ISS Suppl. 21, 1981,19-21 LA - ENG CD - BJDEA AB - CBAC COPYRIGHT: CHEM ABS A review, with 9 refs., on diseases caused by occupational exposure to air pollution by vinyl chloride. (75-01-4 Vinyl chloride) RN - 75-01-4 EM - 6201
24 SI - CA/095/216059K AU - Has eman JK 5 Hoel DG 5 Jennrich RI AD - Natl. Inst. Environ. Health Sci.* Research Triangle Park TI - Some practical problems arising from use of the gamma multihit model for risk estimation SO - J. Toxicol. Environ. Health; VOL 8, ISS 3, 1981,379-96 LA - ENG CD - JTEHD AB - CBAC COPYRIGHT: CHEM ABS The gamma multi hit model (GMH) Is not recommended as a procedure for risk estn. By permitting relatively high background ests. in spite of zero obsd. rates, the GMH procedure can produce unreasonably high safe dose ests. (e.g., NTA, aflatoxin Bl). (139-13-9 NTA)(1162-65-8 aflatoxin
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Bl) In fact doses at which significant increases in tumor incidence are obsd. may even be deemed safe. By permitting hyperlinearity the GHH procedure may lead to unrealistically low safe dose ests. (e.g., vinyl chloride* MeHgCl). C75-01-4 Vinyl chloride)(115-09-3 Methylmercury chloride) Neither the original
std. nor conservative GMH confidence limits seem adequate for practical application. Moreover, the recent appearance of new confidence limits makes it difficult to know what to use. The GMH procedure employs Abbott's correction, which assumes that the response due to background is totally independent of the response due to added toxic substance. This is a difficult assumption to verify and, as indicated, even a slight departure has a great effect on the virtually safe dose ests. RN - 139-13-95 1162-65-85 75-01-4; 115-09-3; 50-29-3 EM - 8201
25 SI AU AD TI SO LA CD AB
RN EM
CA/095/208805K
Georgieva V ; Tsoneva M
Med. Acad., Sofia
Sister chromatid exchanges in persons occupationally exposed to
vinyl chloride and poly(vinyl chloride)
Genet. Sel.J VOL 14, ISS 2, 1981,132-9
BUL
GESKA
CBAC COPYRIGHT: CHEM ABS Sister chromatid exchange (SCE)
frequence/ in 25 workers exposed to vinyl chloride and PVC
increases to 7.315
0.620 exchanger/cell, compared to 6.03
.+-. 0.280 exchanges/cell in controls. (75-01-4 Vinyl
chlorideH9002-86-2 PVC) The SCE level in lymphocyte cultures of
long-term workers was increased. The SCE distribution in the
control group followed the normal Gaussian distribution, that of
exposed workers, a Charliet distribution.
75-01-4; 9002-86-2
8112
26 SI - CA/095/191627D AU - Prerovska I ; Pickova J j Nepilova J AD - Inst. Hyg. Epidemiol., Prague TI - Literature reports on the damage caused by vinyl chloride and our findings in exposed persons SO - Prac. Lek.; VOL 33, ISS 4, 1981,137-40 LA - CZE CD - PRLFA AB - CBAC COPYRIGHT: CHEM ABS A group of 22 workers employed in coating of cables by PVC was examd. (9002-86-2 PVC) The av. exposure to vinyl chloride was 9.5 yr. (75-01-4 Vinyl chloride)
Light vasoneurotic manifestations were found in 15 persons. A
liver malfunction was found in half of the workers. However, the development of a fibrotizing process of the liver was not directly related to vinyl chloride exposure. RN - 9002-86-2*, 75-01-4 EM - 8112
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27 SI - CA/095/155874Y AU - Antonov VN ; Zalikin AA ; Toropov MS ; Sorokotyaga IS ; Zimin VM AU - II'in BA TI - Chlorinolysis conversion of chloroorganic byproducts to carbon tetrachloride under pressure SO - Khim. Prom-st. (Moscow); ISS 5, 1981,287-9 LA - RUS CD - KPRMA AB - CBAC COPYRIGHT: CHEM ABS High-pressure chlorinolvsis of liq. wastes from vinyl chloride manuf. gave 90-5X yield of CC14. (75-01-4 Vinyl chloride M56-23-5 Carbon tetrachlorlde) The wastes contained 1,2-dichloroethane, 1,2,2-trichloroethane, perchloroethylene, and other org. chlorides. (107-06-2 1,2-0ichloroethane)(79-00-5 1,2 >2-Trichloroethane)(127-18-4 Perchloroethylene) The chlorinolysis was carried out at 480-500.degree, and 19-25 MPa during 4.6-6.4 min with liq. Cl. Steel KhN78T did not corrode at 580.degree, and 32 MPa Cl pressure and thus could be used for the chlorinolysis reactors. RN - 75-01-45 56-23-55 107-06-2; 79-00-5; 127-18-4; 71-55-65 7782-50-5} 12002-48-15 12665-30-45 25322-20-7 EM - 8111
28 SI - CA/095/155713V AU - Soble M AD - Hooker Chem. Corp. Burlington TI - Automatic monitoring systems for determining time weighted average workplace levels: process gas chromatographs SO - DHHS (HIOSH) Publ. (U. S.)5 ISS 81-107, Control Technol. Plast. Resins Ind.,, 1981,107-14 LA - ENG CD - DNPSD AB - CBAC COPYRIGHT: CHEM ABS The use of gas chromatog. systems for monitoring vinyl chloride and polytvinyl chloride) levels in workplace ambient air in a poly(vinyl chloride) manufg. process is discussed. (75-01-4 Vinyl chloride)(9002-86-2 Polyvinyl chloride) RN - 75-01-4; 9002-86-2 EM - 8111
29 SI - CA/095/137739D AU - Schroy JM AD - Monsanto Co., St. Louis TI - Prediction of workplace contaminant levels SO - DHHS (NIOSH) Publ. (U. S.)5 ISS 81-107, Control Technol. Plast. Resins Ind.,, 1981,190-206 LA - ENG CD - DNPSD AB - CBAC COPYRIGHT: CHEMABS A procedure for theprediction of work place pollutant levels was developedwhich utilisesemission rate data and gaussian dispersion models. Vapor emission rate data are presented for estg. losses from equipment, piping, and open pools of pure components when actual data are available. Case
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studies are presented for vinyl chloride and acrylonitrile and are discussed in terms of present Occupational Safety and Health Administration regulations for the materials. (75-01-4 Vinyl chloride107-13-1 Acrylonitrile) RN - 75-01-V, 107-13-1 EM - 8111
30 SI - CA/095/137738C AU - Sawyer RR ; Coppola J AD - EOCOM Corp., Irvine TI - Automatic monitoring systems for determining time weighted average workplace levels* Fourier infrared interferometers SO - DHHS (NIOSH) Publ. <U. S.)J ISS 81-107, Control Technol. Plast. Resins Ind.,, 1981,115-51 LA - ENG CD - DNPSD AB - CBAC COPYRIGHT* CHEM ABS Area monitoring for vinyl chloride, incorporating high-resoln., high-sensitivity Fourier transform IR technol., is described, and application of the monitoring system for other toxic compds. is discussed. (75-01-4 Vinyl chloride) RN - 75-01-4 EM - 8111
31 SI - CA/095/126901Z AU - Chyba A A0 - Zakl. Hig. Komunalnej, Panstwowego Zakl. Hig. Warszawie, Warsaw TI - Toxicity of vinyl chloride administered with formaldehyde SO - Rocz. Panstw. Zakl. Hig.; VOL 32, ISS 1, 1981,23-7 LA - POL CD - RPZHA AB - CBAC COPYRIGHT* CHEM ABS A continuous 7-mo inhalation of 1 mg vinyl chloride/m3 retarded rat blood clotting and learning. (75-01-4 Vinyl chloride) Inhaling 1 mg formaldehyde/m3 for 7 mo did not affect the condition of rats inhaling vinyl chloride or of controls. (50-00-0 Formaldehyde) RN - 75-01-4; 50-00-0 EM - 8111
32 SI - CA/095/126715S AU - Duverger M ; Lambotte M 5 Malvoisin E ; De Meester C 5 Poncelet F AU - Merc i er M AD - Sch. Pharm., Univ. Louvain, Brussels TI - Metabolic activation and mutagenicity of 4 vinyl monomers (vinyl chloride, styrene, acrylonitrile, butadiene) SO - Toxicol. Eur. Res.; VOL 3, ISS 3, 1981,131-40 LA - ENG CD - TOERD AB - CBAC COPYRIGHT* CHEM ABS A review with 130 refs, on the metabolic activation and mutagenicity of vinyl chloride, styrene, acrylonitrile, and butadiene. (75-01-4 Vinyl chloride )(100-42-5 Styrene)(107-13-1 Acrylonitrile )(106-99-0 Butadiene) RN - 75-01-45 100-42-5; 107-13-1; 106-99-0 EM - 8111
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33 SI - CA/095/120311K AU - Knox LC AD - Catalytic* Inc.* Philadelphia TI - Design of a high-containment polymerization process SO - DHHS (NIOSH) Publ. (U. S.)*, ISS 81-107, Control Technol. Plast. Resins Ind.,, 1981,207-29 LA - ENG CD - DNPSD AB - CBAC COPYRIGHT: CHEM ABS A plant for the prodn. of PVC and vinyl acetate-vinyl chloride copolymer is described which provides several systems for reducing exposure of employees to vinyl chloride in the atm. to acceptable levels. (9002-86-2 PVC)(9003-22-9 Vinyl acetate-vinyl chloride copolymer)(75-01-9 Vinyl chloride) The protective measures, discussed in detail, are a breathing air network, gas chromatog. monitors, lower explosive limit detector and alarm system, gas holder in recovery system, fugitive emissions capture system, reactor safing procedure and water displacement system, and double mech. seals. RN - 9002-86-2! 9003-22-9*, 75-01-9 EM - 8110
39 SI - CA/095/120308Q AU - Tamburro C-H j Kupchella C ; Taylor K ; Landau E ; Maricq H AD - Am. Public Health Assoc., Washington TI - Screening for the early detection of disease in individuals exposed to vinyl chloride SO - Report; ISS EPA-560/6-81-0025 Order No. PB81-162989,, 1981,18 pp. LA - ENG CD - D8REP AB - CBAC COPYRIGHT: CHEM ABS A prospective collaborative study was conducted to compare the effectiveness of 9 clin. techniques in the detection of liver damage due to vinyl chloride monomer exposure. (75-01-9 Vinyl chloride) A chem. exposed and medically monitored worker population was identified by hlstopathol. and biochem. documentation. The following 3 techniques were noninvasive: (1) grey scale ultrasonog. of the liver; (2) microvascular skin capillary assessment; and (3) urinary anal, of glycosaminoglycan (GAG) excretion. The 9th technique was the std. 99mTc-S colloid liver-spleen scan. The screening studies were performed on a randomly selected group of chem. workers. All 9 techniques were analyzed for their sensitivity and specificity as compared to results of the liver biopsy and biochem. blood test classification. Although all 9 screening techniques had a sensitivity and specificity sum >1, none were better than could be explained by chance or the use of the biased coin. Reclassification of the population into those with more severe biochem. abnormalities improved the sensitivity of all screening tests, but only the sensitivity and specificity sum for the GAG test was significant. There was no correlation between any pair of screening tests. None of the 9 screening tests agreed with the biopsy results better than might be obtained by biased coin or chance. These screening studies as
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presently constituted* do not provide sufficient sensitivity and specificity to warrant their use in community screening for subclin. asymptomatic hepatic injury due to chem. exposure. RN - 75-01-$ Ell - 8110
35 SI - CA/095/0$8$02W AU - Mornet J ; Paul P TI - Method and apparatus for burning corrosive residues SO - Ger. Offen. PATENT NO. 3023807 01/15/81 (Rhone-Poulenc Industries S. A. ) LA - GER AB - CBAC COPYRIGHT: CHEM ABS The app. includes a cylindrical combustion chamber* a burner on the base of the chamber* a combustion gas outlet connection* and a lid on the top of the chambers. The app. is maintained under a given pressure so that the turbulent air flows are introduced from the base of the flame to the chamber coaxial to the rotational axis for combustion* pulverisation, and introduction of the residue to the combustion zone and adjustment of the flame shape. Thus* air flows are introduced to the app. at 3-20 mm under atm. pressure for combustion of waste gas contg. vinylchloride 28.9, N 67.3* end 0 3.8X at 110.degree, with a stable flame; the flue gas from the combustion chamber contains Cl 0.05* HC1 6.$, N 71.85* C02 1$.5* 0 2.6, and water $.6X. (75-01-$ Vinylchloride) RN - 75-01-$ EM - 8109
36 SI - CA/095/0$8$01V TI - Determination of vinyl chloride in air SO - Jpn. Tokkyo Koho PATENT NO. 81 05338 02/0$/81 (Kankyo Rikagaku Kenkyusho K. K.) LA - JPN AB - CBAC COPYRIGHT: CHEM ABS Air contg. a small amt. of vinyl chloride (I) is passed through a dust filter* a U-tube contg. Cr03-impregnated filter paper or perlite* and a U-tube contg. soda lime in that order* UV-irradiated to decomp, the I, and passed through water to det. the I content by measuring the elec, cond. of the aq. soln. (75-01-$ Vinyl chloride) The U-tubes are for oxidn. of NO and removal of N02* S02* H2S* C02, and (or) NH3. RN - 75-01-$ EM - 8109
37 SI - CA/095/0$8177B AU - Makarova VV ; Kaliberdo LM ; Torgasheva AA AD - Inst. Neft. Uglekhim. Sint., Angarsk TI - Trans formation of chloroorganic and organic compounds under conditions of thorough catalytic oxidation over a platinum catalyst SO - Prom. Sanit. Ochistka Gazov; ISS 1* 1981,12-13 LA - RUS CD - PSGAD AB - CBAC COPYRIGHT: CHEM ABS Dichloroethane (I), CCl$, C2H$, and
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PhBu can be removed from waste gases assocd. with CH2:CHCl manuf. by catalytic oxidn. ov'er a Pt-Al.203 catalyst. (1300-21-6 Dichloroethane )(56-23-5 Carbon tetrachloride )(74-85-1 Ethylene )(104-51-8 Butvlbenzene)(75-01-4 Vinyl chloride) Thus* at 450.degree, and space velocity 1000 h-l the removal of I from waste gases contg. 0.070-0.155X I by catalytic oxidn. was 97-99.9X. RN - 1300-21-6; 56-23-5? 74-85-15 104-51-85 75-01-4
EM - 6109
38 SI AU AD TI SO LA CD AB
RN
EM
CA/095/048063M Houpt PM ; Langeweg F Div. Technol. Soc.* TWO* Delft Monitor for measuring the total concentration of reactive hydrocarbons in ambient air based on their chemiluminescence reaction with oxygen atoms Anal. Chim. Acta} VOL 124, ISS 1, 1981,15-22 ENG ACACA CBAC COPYRIGHT: CHEM ABS The monitor functions by measuring the intensity of the chemiluminescence radiation at 309 nm which is emitted during the reaction of hydrocarbons with 0(3p) atoms. The system comprises a specially-developed stable source of at. O, a detection unit for measuring the intensity of the chemiluminescence radiation, and a device for preconcn. of the hydrocarbons to be detd. The sensitivity of the monitor depends on the concn. and reactivity of the hydrocarbons, and is greatest for unsatd. compds. For butadiene, the detection limit is 3 ppb, and response is linear over the range 0-2500 ppb. (106-99-0 Butadiene) The monitor can also serve as a detector for unsatd. hydrocarbons in gas chromatog. 106-99-05 71-43-25 74-82-8; 74-84-05 74-85-15 74-86-25 74-98-65 74-99-75 75-01-45 95-47-65 100-41-45 106-97-85 106-98-95 108-38-35 108-88-35 110-54-35 115-07-15 115-11-7} 142-82-55 463-49-05 590-18-15 624-64-65 17778-80-2 8109
39 SI - CA/095/036606C AU - Politzer P 5 Trefonas PI 5 Politzer IR 5 Elfman B AD - Dep. Chem., Univ. New Orleans, New Orleans TI - Molecular properties of the chlorinated ethylenes and their epoxide metabolites SO - Ann. N. Y. Acad. Sci.5 VOL 367, ISS Quantum Chem. Biomed. Sci.
1981,478-92 LA - ENG
CD - ANYAA AB - CBAC COPYRIGHT: CHEM ABS The initial results of a computational
study of the chlorinated ethylenes and their epoxides were presented, with particular attention devoted to those properties which may be related to the reactivities (specifically carcinogenicities) of these mols. Detailed calcns. of their optimum structure were carried out, and stabilities, dipole moments, charge distributions, and epoxide C-0 bond strengths
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were detd. and discussed. For the epoxides, most of this information* including the structural data* has not previously been available. Thus, this will help to bring about a better understanding of the biol. activities of the chlorinated ethylenes* and of the manner in which these activities are related to the nos. and locations of the Cl substituents. Particularly promising in this respect are the qual. assessments of the epoxide C-0 bond strengths. RN - 74-85-lj 75-01-45 75-21-8; 75-35-4; 79-01-6', 127-18-4; 156-59-2; 156-60-5? 7763-77-1; 16650-10-5; 16650-11-6; 16650-12-7', 16967-79-6; 68226-83-5 EM - 8109
40 SI - CA/095/001414M AU - Wisniewska-Knypl JM ; Sokal JA ; Klimczak J ; Dajniak A AU - Bogdanikowa B AD - Ind. Toxicol. Branch, Inst. Occup. Med., Lodz TI - Protective effect of methionine against vinyl chloride-mediated depression of nonprotein sulphydryls and cytochrome P-450 SO - Toxicol. Lett.', VOL 8, ISS 3, 1981,147-52 LA - ENG CD - TOLED AB - CBAC COPYRIGHT: CHEM ABS Potentiality of a protective effect of DL-methionine against hepatotoxic action of vinyl chloride (VC) was assessed on rats, induced with phenobarbital and thereafter exposed to 50,000 ppm VC for 5 h. (59-51-8 DL-Methionine)(75-01-4 Vinyl chloride) This extremely high dosage of VC warranted the appearance of drastic symptoms of liver injury in the course of 20 h postexposure. DL-Methionine in a dose of 1 g/kg given by gavege prior to the VC-exposure counteracted the VC-provoked depletion of nonprotein sulfhydryls and destruction of cytochrome P 450 in the liver. (9035-51-2 cytochrome P 450) In the methionine-pretreated rats, the phenobarbital-induced synthesis of microsomal proteins in the livers was maintained during the postexposure period, contrary to the nonpreTreated animals. It may be justified to apply methionine as a prophylactic agent in cases of occupational exposure to VC. RN - 59-51-8; 75-01-4; 9035-51-2 EM - 8108
41 SI - CA/095/001194Q AU - Stott WT ; Watanabe PG AD - Toxicol. Res. Lab., Dow Chem. USA, Midland TI - Risk assessment of exposure to vinyl chloride SO - Pure Appl. Chem.; VOL 53, ISS 2, 1981,593-5 LA - ENG CD - PACHA AB - CBAC COPYRIGHT: CHEM ABS A review, with 6 refs., of the use of lab.-animal data on the chronic bioassay of vinyl chloride, its pharmacokinetics, and its macromol. interaction in assessing the carcinogenic risk vinyl chloride poses for humans and the selection of math, models to est. the risk quant. (75-01-4 Vinyl
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chloride) RN - 75-01-4 EM - 8108
42 SI - CA/094/168877F AU - Yeh K 5 Chiang C ; She S ; Wang T AD - Fac. Public Health. Beijing Med. Coll., Peking TI - Lipid peroxidation induced by vinyl chloride SO - Pei-ching I Hsueh Yuan Hsueh Paoj VOL 13 ISS 1> 1981,19-23, 36 LA - CHI CD - PCIPD AB - CBAC COPYRIGHT: CHEM ABS Vinyl chloride and CC14 induced lipid peroxidn. by the rat liver homogenate in vitro. (75-01-4 Vinyl chlorideM56-23-5 Carbon tetrachloride) Pretreatment of rats with Na phenobarbital (an enzyme inducer) increased vinyl chloride-induced lipid peroxidn. Inhalation exposure of rats to 50000 ppm vinyl chloride for 6 h resulted in an increased level of lipid peroxides in the liver microsome when examd. 20 h later. Lipid peroxide levels in the liver mitochondria remained unchanged. When rats were pretreated with Na phenobarbital and exposed to 5000 ppm vinyl chloride, lipid peroxide levels increased in the liver microsomes as well as in the liver mitochondria. RN - 75-01-45 56-23-5 EM - 8106
43 SI - CA/094/151578M AU - Barbin A ; Bartsch H ; Leconte P > Radman M AD - Div. Environ. Carcinogen., Int. Agency Res. Cancer, Lyon TI - Studies on the miscoding properties of 1N6-ethenoadenine and 3>N4-ethenocvtosine, DNA reaction products of vinyl chloride metabolites, during in vitro DMA synthesis SO - Nucleic Acids Res.; VOL 9, ISS 2, 1981,375-87 LA - ENG CD - NARHA AB - CBAC COPYRIGHT: CHEM ABS l-N6-Ethenoadenine (EA)(I) and 3,N4-ethenocytosine (EC) are formed when electrophilic vinyl chloride (VC) metabolites, chloroethylene oxide (CEO) or chloroacetaldehyde (CAA) react with adenine and cytosine residues in DNA. (13875-63-3 l-N6-Ethenoadenine)(55662-66-3 3,N4-ethenocytosine)(7763-77-1 Chloroethylene oxide )(107-20-0 Chloroacetaldehyde)(73-24-5 adenine)(71-30-7 Cytosine) They were assayed for their miscoding properties in an in vitro system using Escherichia coli DNA polymerase I and synthetic templates prepd. by reaction of poly(dA) and poly(dC) with increasing concns. of CEO or CAA. Following the introduction of etheno groups, an increasing inhibition of DNA synthesis was obsd. DGMP was misincorporated on CAA- or CEO-teated poly(dA) templates and dTMP was misincorporated on CAA- or CEO-treated poly(dC) templates, suggesting that EA and EC may miscode. The error rates augmented with the extent of reaction of CEO or CAA with the templates. The potentially miscoding properties of EA and EC may explain why metabolically-activated VC and its reactive
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metabol i : ?s specifically induce base-pair substitution mutations in Salmonella typhimurium. Promutagenic lesions may represent one of the initial steps in VC- or CEO-induced carcinogenesis. RN - 13875-63-35 55662-66-35 7763-77-15 107-20-0} 73-24-55 71-30-75 75-01-4
EM - 8106
44 SI AU AO TI
SO LA CD AB
RN EM
CA/094/115729C Spengier S 5 Singer B Dep. Mol. Biol.* Univ. California* Berkeley Transcriptional errors and ambiguity resulting from the presence of l*N6-ethenoadenosine or 3>N4-ethenocytidine in polyriconucleotides Nucleic Acids Res.5 VOL 9, ISS 2, 1981,365-73 ENG NARHA CBAC COPYRIGHT: CHEM ABS 1,N6-Ethenoadenosine (epsilonAMI) and 3*N4-ethenocytidine (epsilonC) in copolymers with unmodified nucleosides were transcribed using DNA-dependent RNA polymerase in the presence of Mn2+. (39007-51-7
1,N6-Ethsnoadenosine)(39007-52-8 3,N4-Ethenocytidine) Nearest neighbor anal, of the products showed that epsilonA directed incorporation of A>U>C while epsilonC directed the incorporation of U.gtoreq.AC. Neither directed G into the complementary polymer. Such misIncorporations resulting from epsilonA and
epsilonC, compds. that are formed in vivo by the carcinogen vinyl chloride* may have a biol. role as promutagens. (75-01-4 Vinyl chloride) 39007-51-75 39007-52-85 75-01-4
8105
45 SI - CA/094/108443B AD - Research Triangle Park TI - National emission standards for hazardous air pollutants} alternative test method for vinyl chloride in solvents and poly(vinyl chloride) resins SO - Fed. Regist.5 VOL 46, ISS 29, 1981,12188-90 LA - ENG CD - FEREA AB - CBAC COPYRIGHT: CHEM ABS An alternative to EPA method 107 for detg. vinyl chloride in PVC resin, resin slurry, wet resin, latex, resin-solvent solns., and solvents is proposed under the Federal Clean Air Act. (75-01-4 Vinyl chloride )(9002-86-2 PVC) The alternative method involves direct injection of a liq. sample into a gas chromatograph equipped with a column of 20/ Tergitol E-35 on 60-80 mesh Chromosorb W AW and a flame ionization detector. The limit of detection in dry PVC resin is 0.2 ppm.
RN - 75-01-45 9002-86-2 EM - 8104
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