Document NE90G2Z18wLpdRXn2JqBkr67Q

D e p r i n t s s e n t u n d e r s e p a r a t e c o v e r : " G a s o l i n e I n t o x i c a t i o n , " "An Ap p r a is a l o f th e H azards As s o cia t e d w it h th e D is t r ib u t io n and Use o f Leaded G a s o lin e I I - Gar age M ech a n ics " and "H azards in t h e H a n d lin g of E t h yl F lu id and Leaded G a s o lin e ." . n u a r y 1 5 , 19 A? D r . F r a n k V. Kon zelm an n , D irector of Laboratories, At la n t ic City H o sp ita l, ' A t l a n t i c C i t y , Hew J e r s e y . Dear D i . Kon zelm an n : l o u r l e t t e r o f D e c e m b e r pO a d d r e s s e d t o E t h y l C o r p o r a t i o n h a 3 b e e n r e f e r r e d t c me f o r r e p l y , s i n c e I a n d my a s s o c i a t e s i n t h is Laboratory have conducted the experim en tal and t o xico lo gic work on a l l p h a ses o f th e p r ob lem o f g a s o lin e c o n t a in in g t e t r a e t h yl lea d . I n cid e n t a lly the problem p r esen ted by you in t h is c a s e is n o t ne-v t c u s , s i n c e t h i s L a b o r a t o r y , t h r o u gh members o f i t s s t a f f , is r e s p o n s ib le fo r th e work oi the Coron er oi H am ilton Cou n t y w it h r e s p e c t t c t h e d e t e r m in a t io n o f t h e ca u s e o f d e a t h In 3uch I n s t a n c e s . The p r oblem i s n o t a lwa ys s im p le , and som etim es i t must be adm itted, I t goes u n solved . . In con n ection w it h the use of leaded g a s o lin e a s fu e l in a u t o m o b iles, t h e r e i s no t o x ic com bu stion p r od u ct wh ich r e s u lt s from th e u se of t h is fu e l wh ich com p lica t es th e p ic t u r e o f a cu t e I n t o x ic a t io n from e xp o s u r e t o e xh a u s t g a s e s . The le a d compound p r e s e n t i n t h e f u e l in low co n ce n t r a t io n Is burn ed to in o r ga n ic lea d compounds, wh ich a p p ear in th e exh a u st gas In low co n ce n t r a t io n . Under s u it a b le cir cu m s t a n ce s i t m igh t c o n c e iva b ly o ccu r t h a t some d e gr e e o f m ea su r a b le lea d a b s o r p t io n would r e s u l t . H owever, I t is n ot p o s s ib le th a t such a b sor p tion could occu r to such an ext e n t as to b e s i g n i f i c a n t o ve r an y s h o r t p e r io d o f t im e . The e xp e r im e n t a l o b s e r va t io n s made by o u r s e lve s t o get h er w it h th ose o f the Un ited S t a t e s Bu r ea u o f M in e s , h a ve shown t h a t t h e le a d exp o s u r e i s so s lig h t as to be I n s ign ifica n t over sh ort p eriod s of tim e,- th a t I s , h o u r s, days or weeks. There Is n o t h in g, t h e r e fo r e , In t h is xu el wh ich would p rod u ce a p ic t u r e d i ffe r e n t from t h a t o f o r d in a r y ga so lin e . I n v e s t i g a t io n s made on t h i s s u b je c t by t h e Bu r eau o f Min es were p u b lish ed so lon g ago th at the b u lle t in s of the p u b lica t io n are no lo n ge r a v a i l a b l e . M or eover , m ost o f t h e p u b lis h e d work on t h is s u b j e c t i s now ou t o f p r i n t I n t h e for m o f r e p r i n t s , b u t I am sen d in g you s e ve r a l of th e a v a ila b le r e p r in t s in wh ich w i l l be fo u n d r e f e r e n c e s t o t h e p r e v i o u s p u b l i c a t i o n s w h ich I am s u r e yo u can fin d in any good m ed ica l li b r a r y . I f any fu r t h e r q u e s t io n s a r i s e I n you r mind a f t e r exa m in a t io n o f t h e p u b lis h e d m a t e r i a l, I s h o u l d b e v e r y g l a d t o h a v e t h e m b r o u g h t t o my a t t e n t i o n . Cord ially you rs, DAK e f N13964 I .o b e r t A . Ke h o e , M. D-