Document NE8pVXEKKJvGVdp4zd66QovGE

Co3rMpMooradtie TDeieeplaorgmyent &3MCroinve,sBsueitni220o-28.02 IM cma Janu27a, 2r00y3 eer iid al 1 DocumentProcessing Center EOfPfiAceEoasftPo-lRloutoimon6P4r28eAtvtu:eSanencttdiTioonxoi(cns) U12S0E0PPeAansylvaiaAveaveNW ~ WashiDCn2g046t0-o00n01 RE: TPSCeAr(E)fSlSuuU lfoonaP tre(PoP ROSoSU)L BCcMAIStSE #S2Ia7O9M Nn5:-D3eoE 9c3ketN No.T SEHQA -998-L374 `Dear DocketCoordinators: `3geMnehraatspiornervioeusplyrinfoordmeudtchetEPiAv(sSeteupldtyeidmnbeeartv1s4c,eo1n9ld9u8co)toepfdtwhmietreehspnuoltttassosafiulammult p`geernfclruaotrioooncptuapnsesualtfhoentawteo(hPiFgOhSe)sitdnowsheliecvheplesr(i1n.a6taalnmdo3rt.a2lmigt/yokcgc/udrarye)d.iIntMh.e Fy tshuabtsmeqoureeaptrleyciinsfeolrymdeefditnheedEthPeAN(Moar-ch2O8b,20s01e)orfLtvheevreeels(dul0t.-s4omfEg/afkfgo/lfdloaewy-)cuapnstdttuhsdey. mecfohrthaeobnserviedtosxicimty. dIenftiondeatyh'esdsousbem-irsessipoonn,s3efMohratshenepewrirneastualtlsetffoerctespporretfvirooumslasytoubsdeyrcvoendd.ucItMedhtaosbetter rpeecseliivtetedraatftinhaellroewpeosrtt(msaotoeemnacllotsrueraet)mienndtilceavteiln(g0a.n4cmfgf/ekcgt/odnamy)etahnaptuwpasbsotdatyiwsteiicaglhlyt seifgfneicftiocannmte(apn<p0u.p05b)oodnypwoesit-gnhattpaelrdaliytst1er-a5lswohdiesnpcloamypedaraeddotseo-croenstproonlsleiotevresr.tThhee `rcaonngfeiodefndcoesientsetrevsatleodf(t0h4e,b0e.n8c,h1m0a,r1k.d2o, s1e.6r,eapnrdes2e.n0tmign/gkag/1d0a%y)d.ecTrheaesleoiwnemr9ea5n%pup `weightperltteronpost-natalday 1was0.88mg/kg/daymatemaldose. PleasecontactJohnButenhoff (651-733-9162)ifyouhaveanyquestionsorifwecan PrSincerely, M StaffVicePresidentand MedicalDirector Enclosure