Document MyXq6xDrXBaOvNGjvB7p3RNa

3Ldl Iiiiltaslmes AMaflia ANDREW FLETCHER,PRESIDENT K.C . BROWNELL, VICE PRESIDENT J. A. MARTINO, VICE PRESIDENT M.M. ZOLLER.VICS PRESIDENT ROBERT UNDLEY ZIEOFELD, SECRETARY-TREASURER 60 EAST 42n d STREET NEW YORK 1T,N.Y. MANFRED BOWDITCH DIRECTOR OF HEALTH AND SAFETY May 15, 1958 Robert A. Kehoe, M. D. Director, Kettering Laboratory University of Cincinnati Eden Avenue Cincinnati 19, Ohio Dear Bob: Herewith are a copy of.a recent letter to Harriet Hardy and an excerpt comprising the pertinent part of her reply. The paper by S. Moeschlin, translated by Brugsch, is a double-spaced affair of 19 pages, with the title "The Clinical Picture and Therapy of Lead Intoxication with Report of a Fatal Case of Toxic Nephrosis Treated with Cal cium Versenate," the German version having been published in a Swiss medical journal last August. I think it well worth consideration by you, with the possibility of the publication of all or some part of the translation in one of our journals in mind, but I find it of enough value right here not to want to let it out of my hands for too long. Do you feel that you could read and return it to me with your comments reasonably soon? If not, I can submit it elsewhere, pending a time when you are less rushed, assuming that so miraculous a circumstance ever transpires. MB: GP Enclosures LEAD INDUSTRIES ASSOCIATION 60 East 42nd Street New York 17, N. Y. MANFRED BOWDITCH DIRECTOR OF HEALTH AND SAFETY Hay 2, 1958 Harriot L* Hardy, H. D. Massachusetts General Hospital Boston 1L, Massachusetts Bear Harriets <7.j j Thank you for the copy of the papep-byhbeschlin,'''translated by Brugsch, which I note that you hare sarkepx*,Mis,''iS, iraportantXltihink." V Being rather more than rushed^ \ cannot/pretend to have read the 19 pages in full, but I have gone through. it\duffieiehtly to be of two minds, or perhsos three or four. .... ,,.w ... Causation of the fi5%t two bfs\he fbuV cases is attributed to lead tetraethyl residues in pis$e' and automobile englhbs, and this siay be correct. But there has been so saushj irresponsible) published talk about lead hazards to the public from isotor exhausts that 1 Wwooulld w> ant to see this differentiation stressed. In/the last of the foui*'na'ses, the occupation of the patient is not stated, whiqfa/ seeais unfortunate. i As\io therapy, in the first case is not stated, that in the second appear Hp have.b'eeh sodium citrate, followed by EBTA, that in the third a combinktidn'OfT-SSTA and BAL, and that in the fourth EBTA alone, the last two being those that wound up fatally. Quite a therapeutic assortment. fc'if 0014365 y? v N18585.01 Harriet l. Hardy, M, D. -2- May 2, 1958 Granting that lead tetraethyl has its hygienic drawbacks and that we have our reservations as to EDTA, is the author Justified in his two quite emphatic recommendations {1} that the lead tetraethyl in motor gasolines b replaced by benzol, and () that we abandon DTA and go back to sodium citrate? Incidentally, the SETA used in these cases was apparently the Swiss product, Calcium H&usmsnn. I have a single ampule of this* Would it be worth whilo to turn this over to a highly competent chemist, to look, for possible differences between this and the' American product? I have discussed the paper briefly by telephone with Hervey, and we may talk farther about it while I am in Boston nest Monday, Tuesday and 'fedneaday, on what I anticipate to be something of a idiirlwind trip. He ap parently knows nothing of the author, and doubts if Dr* Brugsch does either. I would be glad to common tilth you also, if your interest is such as to war rant it. finally, what would you Think of seeking yehae*s reaction to this rather singular document? Sincerely, CXa %^> :.m% g p ccs Dr. Dlkins K 0014.970