Document MMZJ56YvKvE0qrKo6jpQ3rw2z

KATHRYN M. DECKER DIHECT DIAL NUMBER <2011 960-8092 /a*57/ ^0 Pitney. Hardin. Kipp & Szuch (MAIL TO> P.O. BOX 1945 MORRISTOWN. NEW JERSEY 07962*1945 (DELIVERY TO) 200 CAMPUS DRIVE FLORHAM PARK. NEW JERSEY 07932-0950 FLORHAM PARK (201) 966-5300 NEW YORK (212) 926-0331 TELEX S4SOM FACSIMILE (201) 966-1590 September 10, 1993 Gregory D. Winfree, Esq. Litigation Counsel Union Carbide Corporation Law Department, E3-285 39 Old Ridgebury Road Danbury, CT 06817-0001 Re: Colby v. Union Carbide Corporation Docket No. L--1979--91___________ Dear Greg: Enclosed please find C.V.'s of the foil owing potential toxicology experts for Union Carbide in this matte r. 1. Dr. Rudolph J. Jaeger 2. Gary L. Lage, Ph.D., DABT 3. Laura C. Green, Ph.D., DABT As we discussed, Dr. Jaeger is presently servihg as the defense expert against Union Carbide in the matter entit ed Union Carbide Corporation v. Aetna Casualty and Surety Company , et al. This matter is also venued in Middlesex County. After you have the opportunity to reviejw thes^ C.V.'s, please contact us at the beginning of next week to dis cuss the selection of our toxicology expert. PRIVILEGED AND Sincerely ya urs, "CONFIDENTIAL MATERIAL SUBJECT TO PROTECTIVE ^Y~ ORDER" KKAATTHHRRYYNN MM. ti ECKER KMD:ss enclosures cc: Robert L. Hollingshead, Esq. (w/o enc.) UCC 075718 GARY L. LAGE, FfcJk, DART EDUCATION 1967 PhJ3^ Pharmacology, University of Iowa 1962 MS., Pharmacology, University of Iowa 1963 B.S., Pharmacy, Drake University REGISTRATIONS Diplomate, American Board of Toxicology EXPERIENCE Dr. Lage is a Principal at ENVIRON Corporation. He has over 25 yean of srience in toxicology, both in its academic development as a scientific discipline and in umpiring activities for industry and government. He has experience in developing itive solutions to environmental problems through the use of risk assessments, and is widely )gnlzed for communicating complex issues of toxicology and risk assessment to 1c audiences. His work at ENVIRON has included the following: Provided expertise in siting and permitting a commercial hazardous waste {incinerator with development of a multiple pathway risk assessment and communication of results to regulatory agencies and public interest groups. Provided strategic guidance and expert evaluation in litigation involving chlorine dioxide exposure to construction workers at a pulp and paper f Directed a TSCA 8(e) CAP audit for a major chemical manufacturer. In iddition to developing a protocol for the audit, developed a data base to asstet the antitors and to assure retrieval of the over 10,000 studies reviewed. Reviewed a risk assessment for development of real estate on the shores cf Lake Michigan to assure that the risk assessment would be acceptable to the lending and regulatory agencies. Evaluated the potential risks associated with a CPC substitute in foam imitation to workers or to residents of homes insulated with the product I Assisted a dient in strategic planning for evaluating indoor air concentrations of off-site residences as a result of ground water contamination with volatile chlorinated organic hydrocarbons, and assisted in the protocol development and analysis of indoor air and interpreted the results for the corporation and the residents. UCC 075719 GARY L, LAGE, PfauOn DART Evaluated the potential risk to workers due to formaldehyde contamination of an agricultural product. Assisted a client In the strategic planning of protocol development and evaluation of potential indoor air contaminants at a former industrial facility due to ground water contamination with freon and chlorinated hydrocarbons, and presented ttye results to the current employees of the facility. Evaluated the potential advene affects from dioxin materials for both worker exposure and the exposure of cons developed from these materials. ti trally mined < (ducts Assisted a client in the strategic planning and site characterization for a $upcrfund site to assure that the sampling plan, analytical procedures, and detection limps would meet the needs of the risk assessment to be conducted for the site. | Assisted four clients in developing protocol for TSCA 8(e) CAP audits. Assisted a client in negotiating a protocol for a risk at a Super&nd site to be performed by the EPA contractor to reduce the level of antagonism that plight develop after the risk assessment was developed. Performed an updated risk assessment and evaluation of a Superfund site to incorporate current toxicology information and documented biodegradation into the risk assessment process. !I Assisted a client in designing and performing a risk assessment for a hazardous waste incinerator. r. Evaluated the hazards and potential liabilities for an insurance company due to a inappropriately applied pesticide in a spartment complex. Served as an international expert to review hazard assessments developed for 65 chemicals for the Ontario Ministry of the Environment. Assisted a client in evaluating potential off-site risks due to an industrial ftrility using 13-butadiene and incorporated current toxicological information on the mechanisms of toxicity of 13-butadiene, In a product liability case, evaluated the claim that a family was poisoned jdue to mercury goritaritiario of a commercial juice product Served as an expert toxicologist in litigation concerning trichloroethylene eiposure due to ground Water. I 2- UCC 01572 GARY U LAGS, PfcJ)n DABT Assisted in determining the necessity for a product recall due to a manufacturing error that caused significant quantities of alkaline material to be found in a enmumgr juice product The product was recalled prior to any documented human exposure. Evaluated the potential risks due to chlorinated hydrocarbon conaminatian of ground water subsequently used in a consumer product In a malpractice case, evaluated the potential adverse health affects from an alleged prescription error to the recipient Assisted in performing multipathway risk assessments associated with post^emediation levels of PCBi in gas transmission locations. Prior to joining ENVIRON, Dr. Lage was Vice President and Human Health Practice Leader at Roy F. Weston, Ina, where be was responsible for toxicological, risk assessment, and industrial hygiene issues. Prior to that bo saved as Chairman of the Department of Pharmacology and Toxicology, and Professor of Toxicology at the Philadelphia College of Pharmacy and Science. He has also held teaching and research positions at thh University of Kansas and the University of Wisconsin. i Dr. Lage's experience in these areas is represented in the following project descriptions: Served as project director and senior scientist for a hazardous waste incinerator project for a major chemical company that included a multipathwsy risk HMcsimiMfr, a traffic study, and a socioeconomic analysis. Performed several risk analyses to support a "no-action" alternative for ground water contaminants at contaminated industrial facilities. Served as an expert in support of a "no action* alternative for a site with complex cyanide contamination in soil. Involved differentiation of toxidty of simplei cyanide compunds compared to complex cyanides. Served as sensor scientist for an evaluation of the risk to pulp and paper ftidlities due to air emitsifint of chloroform. Developed scientifically sound alternative cartier potency values for chloroform, and presented assessments to numerous state and & regulatory agendas. Directed a series of projects involving the determination of risk ftasocifttrd ith PCBs in the gas transmission and distribution industries. UCC 075721 4- GARY L. LAGS, PhJ)* DART Assisted a major metal processing facility in determining areas of impact that would result from accidental chemical releases from the facility to surroui utinQgg residential areas. Determined which residential areas would be expected to experience illness or death due to worst-case chemical releases. Determined the potential adverse health impact to a wnpllng team at an NPL site due to unexpected exposure to dioxins, and communicated results to workers. Assisted a major company in developing risk-based environmental levels cf lithium; helped negotiate with regulatory agencies concerning acceptable levels in pound water. Developed a computer model to predict off-site carcinogenic risks associated with on site air emissions; screening model utilized SARA Title XU emissions information to predict the carcinogenic risk. || Evaluated a risk assessment performed on a cement Idln dagMd to bum fuel derived from hazardous waste. Assisted in presenting results to the regulatory agency and throughout the litigation process. I Directed the permitting process for a water pulp and paper company seekng applicable air permits for a new facility. j Performed an analysis and evaluation of occupational risks posed to workers in a PCB- comamlnated facility, and presented results to owners and workers. j Evaluated potential carcinogenic risk to workers from long-term use of contaminated ground water at a metals manufacturing facility, and presented results to employers. Served ss an expert witness for determining the physiological intoxication as related to motor vehicle operation for numerous vehicular homicide cases. Assessed indoor air concentrations and determined potential health risks ik residences surrounding a petroleum pipeline leak; monitored indoor air and detenninjed action levels for compounds such as benzene. Developed air quality guidelines for 99 toxic chemicals for the city of PhUidelphia, one of the first municipalities to develop such guidelines in the early : 980s. Developed an educational program entitled Toxicology for Non-toxicologies," presented widely to attorneys, environmental managers, and other atutienryg over th^ last ten years. UCC 075722 GARY L LAGS, Phl^ DABT For the Pennsylvania Department of Health, participated in a : investigation of potential hazards from chemical waste sites to evaluate the need for a nkore extensive health assessment Developed a "Chemical Education Outline" to inform individuals and *m\i businesses about chemical hazards in the workplace, with special emphasis ontheOSHA Hazardous Communication Rule. ~T PROFESSIONAL MEMBERSHIPS AND ADVISORY POSITIONS Member, Society of Toxicology; treasurer, 1985*1989. Member, American Society of Pharmacology St Experimental Therapeutics. Founder and First President, Mid-Atlantic Chapter, Society of Toxicoll|>gsr. Member, American Pharmaceutical Association. Member, American Association of Colleges of Pharmacy. Member, International Society for the Study of Xenobiotics. Member, American College of Toxicology. Member, American Association for the Advancement of Science. Member, Genetic Toxicology Association. Member, Drug Metabolism Group. Member, Section of Toxicology of the International Union of Pharmacology (IUPHAR). Adjunct Professor of Toxicology, Drexel University, 1985*. Professor, Weston Institute, 1989-. Member, National Institute of Health, Environmental Health Sciences Review Committee, 1986-1990. External Advisor, NIEHS Aquatic Biomedical Research Center, Medical College of Wisconsin, 198S-. I| Member, Advisory Panel on Health, Safety, and Environmental Affairs, Smith Kline St French, 1984-. rI UCC 075723 -5- GARY Li LAGE, PhJ)., DABT Member* Advisory Committee on Toxic Air Pollutant! for Philadelphia Department of Health, 1981-. 1 Member, Toxics/Health Effects Advisory Committee, Pennsylvania Department of Health, 1984-1988. | Member, Health Hazard Evaluation Panel, Weston, Inc, 1984-1987. Member, Air Pollution Control Board, City of Philadelphia, 1983-19U7. Member, Board of Directors, Toxicology Laboratory Accreditation Board, IzuL 1983-1988. Outside Reviewer, U.S. Navy Toxicology Program, 1983. i Member, Pennsylvania Vietnam Herbicide Information Committee, 1982-198L PUBLICATIONS AND PRESENTATIONS Lage, GX 1992. Drug toxicity. The Merck Manual 16th ed. Lage, GX. 1992. General principles of toxicology; Review of toxicological responses; and. Role of toxicology in risk assessment Papers presented at the Ooverameyn Institutes Symposium on Toxicology for Non-Toxiedlogista, Hihon Head, S.C, July; jalio presented in Washington, D.C, April 1992; Richland, We, November 1991; Washington, D.C, October 1991; April 1991; October 1990; and April 1990, Lage, GX 1992. Methods to conduct riik assessments. Paper presented at Annual ILTA Operating Conference, Houston, Texas, June. Lage, GX 1992. Environmental risk assessments; Techniques and presented at the Governmental Institutes Symposium on Assessments, Arlington, Virginia, April. Lage, GX 1992. General principles of toxicology; Review of toxicological responses; and. Role of toxicology in ride assessment. Papers presented at the Governmental Institutes Symposium on Toxicology for Non-Toxicologists for UX Army Chemical Research, Development A Engineering Center, Aberdeen Proving Ground, Maryland, January. Lage, GX 1991. The TSCA Compliance Audit Program: How to determine which studies to report under TSCA Section 8(e). Paper presented at the Government Institutes Symposium on the TSCA Compliance Audit Program, Arlington, Virginia, October. Lage, GX 1991. TSCA 8(e) CAP audits. Paper presented at the 1991 Toxicology Roundtable Symposium, Long Branch, New Jersey, October. -6- UCC 075724 ....... GARY U LAGS, Ph-D., DABT Lage, OX. 1991. Risk assessment and its uses in environmental regulation, i Paper presented at the Center for Energy and Environmental gympryriiim on Risk Assessment Alexandria, Virginia, October and May. I 1 Lage, Gi. 1991. Risk assessment and bow to cope with SARA Title m. piper presented at the Pennsylvania Chamber of Business and Industry, Harrisburg, Pennsylvania, May. Lage, GX 1990. Introduction to risk assessment - dispersion modeling/risk assessment Paper presented at Clean Air Engineering, Chicago, December. Lage, GL 1990. Causation; Chemically induced disease - the role of toxicology. The Legal Intelligencer, Philadelphia, November 15. Lage, GX 1990. PCB management training. Paper presented to the City Austin Power and Light Austin, Teat* October. T Lage, GI* 1990. The role of risk assessment In evaluating human clean-up alternatives. Paper presented at the Institute for Intel Symposium on Environmental Regulations at Federal Facilities, September. Lage, G.L. 199a Review of chloroform toxicology. Paper Committee of the Alabama Pulp and Paper Industry, * to the Environmental . Ahu, Mandelbaum, I., and GJL Lage. 1989. Cookbook risk assessment: ingredients. Paper presented at Hazardous Waste Management ttHbjhup /CentraL Kershaw, W.C, D.A. Barsotd, TJL Leonard, J. Dent, and GX Legal 1989. Methooyflurane enhances allyl alcohol hepatotozidty: Possible involvement of increased ^crolein formation. Drug Metab, Dfcpot 17:117. Lage, GX. 1989. Toxicity assessment; and Characterization of risk, papers presented at the Government Institute Symposium of Environmental Risk Assessment, Washington, D.G, November. Lage, GX 1989. Bask principles of toxicology. Paper presented at the Environmental Engineering Conference, University of Minnesota, Minneapolis, October; at the Tnifntri<ma1 EiwiiwwwnMtfal FonUD, * T ryn( N.l Lags, GX 1989. Risk assessment methodology: Toxicological aj Paper presented at the Symposium on Risk Assessment of Solid Wastes Institute of Chemical Engineers, Philadelphia, Pa^ August the American Lage, GX 1989. Impact of air toxics regulation on industry. Paper presented at HazmatInternational, Atlantic City. NX June. -7- UCC 075725 GARY L. LAGS, PhJX DART Lage, GX 1989. How environmental professional* use toxical at Hazmat-Intarnational, Atlantic City, NX June. presented Cannon, J.R., PJ. Harvison, and GX T age. 1988. Age related diffi metabolism of allyl alcohol to aaolein by Sprague-Dawiey rats. Toxicologist $'261. Lage, GX 1988. Drug testing: Causation implications. Paper presented to ithe Defense Research Institute Symposium on Workers Compensation, New York, December. Lage, GX 1988. Models of immune system testing. Paper presented to Annual Education Seminar of the Dermal Clinical Evaluation Society, Atlantic City, NX September. Lage, GX 1988. Risk assessment and facility siting; Paper presented at the Government Institute Symposium on Incineration and Thermal Destruction of Hazardtrus Wastes, Philadelphia, Pa^ July. i Lage, GX 1987. Drug taaddty. Th* Mtrck Manual. 15th e<L j Abdelhamid, S., V. Valez, D. Smallwood, and G. Lage. 1967. Toxicological risk assessment at hazardous waste sites: An engineer's perspective. Third Annual Hazardous Materials Management Conference West Lage, GX 1987. The role of toxicology in drug development Presented to the Philadelphia Forum of the American Association of Pharmaceutical Scientists, Fort Washington, Pit, December. * Lage, GX, J. Esch, and J.E. CromwelL 1987. Risk assessment Annual Hazardous Materials Management Conference Minimization of Work-Site and Off-Site Health Risks, Long presented at Third on Right to Know: Calif.J December. Lage, GX 1987. Pharmacology of drugs of abuse; and Technology of drug totting. Papers presented at the Pennsylvania Bar Institute Symposium of Drug Testing in the Workplace, Philadelphia, Pa. and Princeton, NX October. | ! Lage, GX 1987. Air pollutants/air toorics and their interaction with RCRA. presented to the Environmental Forum, Sherman Oaks and Santa Clara, August. Lage, GX 1987. Role of toxicology in understanding chemically induced tional diseases. Paper presented at the Defense Research Institute Academy of Workers Compensation, Boston, June. 1 Lage, GX 1987. Drug testing: The scientific issues. Paper presented at the Federal Publications Symposium on Drugs and Chemicals in the Workplace, Philadelphia and Pittsburgh, May. -8- Ucc 075726 GARY L LAGE, PiuD* DABT Lage, GJL 1986, Environmental toxicology. Paper presented at tbe Departtnem of Pharmacology. Tlie Medial College of Pennsylvania, Philadelphia, December, Lage, GJL 1986. Drug and alcohol teiting in tbe workplace. Papa, present^d at tbe Delaware State Chamber of Commerce Symposium on Drugs, Alcohol, a ad AIDS in the Workplace, Wilmington, DeL, November. Lage, GJ- 1986. Public health problems associated with solid waste resource recovery and recycling. Sponsored by the League of Women Voters of Berks County, ApriL Fancher, R.M., W.G Kershaw, and GA. Lage. 1985. Allyl alcohol toxicity ix Sprague-Dawiey rata: Male vs. female. Paper presented at tbe Undergrt duate Research Symposium, University of West Virginia, September, j Kershaw, W.C, P. Campbell, and GA, Lage. 1985* In vitro dighradn metabolism: Rate-limiting step and alteration following spironolactone pretreatment. DmgMetab* St Dap. 13:635-639. j Warwick, R.O., M^. Smith, MA Grafty, and GA, Lage. 1985. Altered dialti {button and toxicity of dlgltarigenm in fitted mice. Life Sciences 37:775. |r Lage, G.L. 1985. Tbe air we breathe; Do we need a canary? Paper presented at tbe Department of Environmental Resources Symposium: Environmental Hazards and Your Health, Commonwealth of Pennsylvania, March. ! Lage, GA. 1985. Meduudsma of chemical hepatotoxicity. Paper presented at the Department of Pharmacology A Toxicology, University of Texas. March, Also presented to the Department of Pharmacology, The Medical College of P mnsyivania. February. T; Lage, GA. 1985. Mechanisms hi altered digitalis toxicity. Paper Department of Pharmacology, Toxicology St Therapeutics, U: of Medidne, March. to the ity of Kansas School Lage, GJL 1964. fmnabm and change in the science of toxicology! I Paper ]resented at the OSttAChemioal Hazard Communication Standard Symposium, Mamifacturers' Association of Delaware Valley, Valley Forge, Pa, October. |! I Lage, G.L. 1984. The role of toxicology in determining risk pollutants. Paper presented at the American Institute of Symposium: Risk Management of Toxic Air Pollutants, PbBade Lage, GL 1984. Modem toxicology. Paper presented at the Association of Analytical Chemists, Philadelphia, May. I{ -9- trCC 075727 GARY Li LAGE, PhD., DABT Lage, GX. 1984. Health effects of dioxin. Paper presented at the Environmental Health Seminar, Harrisburg, Pa^ January. Lage, GJ-. 1984. Alcohol intoxication. Paper presented at the Toxicology fcr Attorneys Symposium, Houston and Chicago, July. i Lage, Gi, 1983. The science of toxicology as it applies to dioxiiL Paper presented at the Pennsylvania Medical Science Symposium: Toxic Herbicide Exposure, Pittsburgh and Valley Forge, Pa., October and November. Lage, GX. 1983. Extrapolation from species to man. Paper Toxicology for Attorneys Symposium. Valley Forge, Pa^ June at the Lage, GX. 1983. The evaluation of the medical aspects of health/mk assessment. ACS Symposium, White Haven, Pa^ April. Lage, G.L. 1982. The role of dose-response relationships in on Statistics in the Environmental Sciences, Philadelphia, Symposium Volp, ILF., and GX. Lage. 1982. Digitoxln iwemhnHyn by rat, mouse and rabbit NADPH requirement and spironolactone effect Research Comm, in Chem. Path, and Pharm. 38:501-504. R Lage, GX. 1981. Toxicology and laboratory waste. ACS Symposium, King of Prussia, Pa^ November. * Lage, GX. 1980. Dennatotoxicology. Thomas Jefferson University Toxicology, Philadelphia, March. Lehman, L* and GX. Lage. 1980. The effect of chronic rijgitngfn nt cjn subsequent digitoxin biliary excretion in the rat Abstract presented at the test Virginia Symposium for Undergraduate Research, October. Sweeney, ILF., and GX. Lage. 1979. Metabolism of <tigttnarin in the ated ]>erfused rat liver: Effect of spironolactone pretreatment DrugMetab. and 7:28*284. Lage, GX. 1979. Baccalaureate program in toxicology. Veterinary and Human Toxicology 21(3):191. | Lage, GX. 1979. Role of toxicology in the 1980s. Penjerdel Enviroimental Inprovement Committee, Philadelphia, December. Lage, GX* 1979. Opportunities for universities to meet the needs of industrial research and development: The view from academe. Paper presented at the Indusjrial Research and Development Symposium, University of Mississippi, April. 11 I -10- UCC 075728 ____ l.. GARY L. LACK, PhJL, BAHT Volp, RJ?H and GX Lage. 1978. The foie of a major biliary metabolite of rat intestine. Drug Metab, and Disp. 6:418-424. 1r in the Lage, GX 1978. Basic pharmacology. Short course for optometrists, Madison, Wisconsin, November and December. Lage, GX 1978, Safety extrapolations based on comparative pharmacokinetic parameters. Paper presented at the Drug Safety Subsection of the Pharmaceutical Manufacturers Association. Symposium entitled "Practical Pharmacokinetic Considerations in Toxicology," Point Clear, Abu, November. ;i i Lage, OX- 1974-1978, Toxicology: The study of poisons. Paper presented at Beloit and Ripon Colleges and at the following branches of the University of Wisconsin: Ean Clair, Green Bay, Oshkosh, Plattevffle, Parkiide, Stevens Point and Superior. Richards, L.G,, and GX Lage. 1977. Stimulation of the glucurooidadon of d&ttxagenm- manodigitaKoside by liver homogenates from spironoiainon-pretreated ratsT TaxicoL d AppL Pharmacol 42309-318. || Richards, XGH M.G Castle, and GX Lage. 1977. Ghtcuronidadon of digitaxin and its metabolites by rat and rabbit liver homogenates. Drug Afscoft. d iXipoi 5:469-473. Volp, RJ% and GX Lage. 1977. Studies on the intestinal absorption of bovine xanthine oxidase. Free Sac, E& BhL d Med 154:488-492. ji Lage, GX 1976, liver tissue as a model to predict final metabolic products in man. Paper presented at the National Industrial Pharmaceutical Research Conference, Lake Deiton, Wis. Lage, GX 1975. Bio&vaOabQity and drug disposition. Paper presented at the Northem Illinois Medical Service Representatives, Rockford, BL |j Lage, GX 1975. Hypertension and risk factors in heart disease. Visiting Lecturer Program at the Wiacooiin Heart Association, Milwaukee, Wis. , 11 1 Lage, GX 1971 Marie Clinical Pharmacology. A Cassette Presentation for Extension Services in Pharmacy. Castle, M.G, and GX Lage. 1974. Cleavage by the B-ghicuroaidaat of the waier-solubie metabolites of digitorin excreted in the bile of control and spironolactone pretreated rats. ToodcoL and App. Pharmacology 27:641-647. ii ; ii ' Lage, GX 1973. Mechanisms of drug interactions. Paper presented at the Wisconsin Pharmaceutical Association Meeting. 11 ' -11- UCC 075729 GARY L IAGE, PhJh, DART Castle, M.G, and GX Lage. 1973. Biliary excretion and Hepatic dijit/wfa and its metabolites following spironolactone pretr Chcm fart* and Pham 6:601-612. tratipn of H3of rani Res. Comm, Castle, M.Q, and GX Lage. 1973. Exaction of tf-digittudn and its metabolites following spironolactone pretreatment in rats. Drug Mrtah and Disp. 1:590-597. Castle, M.Cm and G.L. Lage. 1973. Metabolism and distribution of Wffinrin |n the rat Arch hum. Pharmacodyru Therap. 203:323-335. FT I Castle, M.G, and GX Lage. 1973. Enhanced binary excretion of digitnzin fallowing spironolactone pretreatment as it relates to the prevention of toridty. Research Comm, in Cham. Path and Pharmacol 5:99-106. Lage, OL 1972. The time lag in medical science. DrugAbuse Resource Manual ofKansas, Castle, M.G, and GX Lage. 1972. Effect of pretreatment with phenobarbitAl or B-diethylaminoethyl ( levels in blood, Heart, and liver of rats at various times after H*-riigitoxin, Biochem. Pharmacol. 21:1449-1455. Lage, GX 1971. Clinical implications of drug interaction information. Amer.JPhanru Educ. 35:770-775. Buck, SJL, and OX Lage. 1971. Possible mechanisms at the prevention of digitcarin toxicity by spironolactone in the mouse. Arch hum Pharmacodyn Therap. 189:192-197. Lage. GX 1969. Current spot removers: How sals axe they? /. qf&msas Pharmacy 45:6. Lage, GX 1969. Over-the-counter products. Paper presented at Pharmacy Extension Program, Garden City, Wichita, and Colby, Kaos. January and February. Lage, GX 1966. Prescription drug abuse. Paper presented at Pharmacy Extension Program, Ksnsas City, Colby, Garden City, Pittsburgh, and Wichita: Kans. January and February. | Lage, GX 1968. Possible therapeutic applications of enayme induction. S. ofKansas Pharmacy 44:6. 1 iI I Lage, GX, and JX Spran. 1968. Bilirubin conjugation by beaptic microsomea from adult male guinea pigs. Arch BtocAem. and Bicphys. 236:175-186. 1 Lage, GX and JX Spratt. 1968. Species variation and sex differences in the in vitro bepatic metabolism of H3-digitoadn. /. Pharmacol and Apert Thcnfy. 159:162-193. -12- UCC 075730 GARY 1* LAGS, PfeJX, DART Spratt, J1*, aad GX. Lage. 1967. Fortran IV program for automatic external standardization, in liquid scintillation spectrometry. Intern, J, Appt^ut Radiation and Isotopes 18:247-252. Lage, G~L, and JX. Spratt 1967. Effect of chlorriana and DDT pretreatment on the metabolism of H'-digitoxin by monkey heart and Hver tissues in vitro. Arch, Intern. Pharmacodyn. Therap. 169:255-261. Lage, Gl*, and J.L. Spratt 1967. Antagonism of intravenous digit reserpine pretreatmem in the mouse, Proc, Soc. Exp. BtoL and lin lethality by 125-^583. Lage, GX-, and JX Spratt 1966. Structure-activity correlation of tbti liethality and central effects of selected cardiac glycosides. /. Pharmacol and Exper. Thar. 152361-508. Lage, GX, and JJL Spratt 1965. H*-digitaxm metabolism by adult male rat /. Pharmacol and Exper. Therap 149:248-256. fa vitro. Lage, GX How to live with today's toxic chemicals. Paper presented over 100 high school and college science groups and to numerous service groups. to FMM0O197.W31 -13- UCC 075731 LAURA C. GREEN, Ph.D., O.A.B.T. EDUCATION: 1981. Massachusetts Institute of Technology, Cambridge, Massachusetts. Ph.D. from the Department of Nutrition and Food Science (renamed Department of Applied Biological Sciences). Ph.D. thesis, "Nitrite and Nitrate: Toxicity, Metabolsm, and Biosynthesis" Discovered that nitrate Is biosynthesized in vivo in humans and in rats by A mammalian process. Investigated the toxicology and pharmacokinetics of nitrate and nitrite. Designed and built a novel automated system for the analysis of nitrate and nitrite in biological and environmental samples. 1975. B.A. with honors in Chemistry, Wellesley College, Wellesley, Mas! husetts. i Also studied Biology, Physics, Philosophy, and Literature. Honors Included: Phi Beta appa, Sigma Xi, American Institute of Chemists Student Award, and Wellesley College Scalar. BOARD CERTIFICATION: Certification in general toxicology -- Dlplomate of the American Board of Dxfcotogyj (D.A.B.T.), 1988. PROFESSIONAL EXPERIENCE: 1989-Present. Senior Scientist and President, Carrferidge Environmental line., Cambridge, MA. 1986-Present lecturer. Division of Toxicology, Massachusetts Institute of Technology. 1985-1989. Vice President lor Environmental Health and Toxicology, Mt a Systems Inc., Cambridge, MA. 1983-1986. Research AffiHale and Project Coordhator for a five-year gtfail from the American Cancer Society lor work in biochemical epidemiology, Department of Apptyd Biological Sciences. Massachusetts Institute of Technology. 1983-1985. Research Director of the Scientific ConfHct Mapping Project arvard University School of Public Health. Developed a new method lor making scientific regulatory decisions about toxic and carcinogenic chemicals in the workplace and envkonmen Go-auttpored a book entitled. In Search of Safety: Chemicals and Cancer Risk (Harvard Urtveftsttv Presfi, 1968). Cambridge Environmental too 56 Chant* Straw CambrtdQi. Mmihuaefti OZMi 617*225*0610 817*225*0813 MX UCC 075732 Laura C. Green, Ph D., DA8.T Page 2 PROFESSIONAL EXPERIENCE (continued): 1978-1965. Consultant In toxicology and risk assessment, self-errploye^L 1981-1963. Postdoctoral. Fellow in Environmental Toxicology* Massachusetts Institute of Technology. Research with Professor Gerald Wogan directed toward d^vj loping dosimeters for icarcinogenic chemicals. Studied the covalent modification of hemoglobiji nd atburrjiin by carcinogens. Determined that blood protein adduction was quantitative ja]d sensitive, and therefore of use in assessing actual human exposures. 1975-1981. Research Assistant* Teaching Assistant, and Predoctoral Tra lee, Department of Nutrition and Food Science (renamed Department of Applied Biological 5< fences), Massachusetts Institute of Technology. Summer, 1974. Research Chemist, Dow Chemical Company, Wayland, Massachusetts. Developed a direct oxidative synthesis method for propylene oxide. SELECTED PROJECT EXPERIENCE: Trichloroethylene and related chlorinated hydrocarbons \i Analyzed and critiqued literature on toxicity of trichloroethylene an related Compounds, Developed expertise m trichloroethylene-induced carcinogenesis irj d In neurologic effects associated with trichloroethylene and Its products of degradation, erved a$ consultant and/or expert witness in several `toxic torf lawsuits in which e es via contaminated drinking water were aleged to have caused significant harm, served ap consultant and expert toxicologist m lawsutts surrounding workplace exposur to trichbroethylene, trichloroethane, and other volatile chlorinated hydrocarbons. Polychlorinated dthenzodloxlns Assessed risks associated with emissions of polychlorinated dttxi odioxins (PCDDs) from paper mW. Served as expert witness in lawsuit concerned wi h possible adverse effects on a lake, the surrounding environment, and the public hen th< Performed quantitative risk assessments tor various exposures to PCDDs; focussed oil excess risks of cancer and on risks of reproductive toxicity. Cambridge Imrironmswttl lac SeChartatStrMt CwnbrtOQi, Mtwihtmm 02141 617*225*0110 017*225*0613 MX ucc 075733 Laura C. Green, Ph D., D A B.T. Page 3 SELECTED PROJECT EXPERIENCE (continued); Benzene and related compounds Developed and applied expertise in benzene-induced leukemia, ormed qualitative and quantitative assessments of risk associated with various ro and levels of exposure. Served as consultant and ejqmrt toxicologist in lawsuits surrounding low-level rttkenvironmental and occupational exposures to benzene. In other tiers, evaluated risks of acute myelogenous leukemia from all known and suspected cau es, including various chemicals, drugs, and radiation. Assessed hazards associated with exposures to benzene, toluene and xylenes emanating from leaking underground storage tanks and above-groIfid spills of gasoline. Mercury Performed an in-depth study on sources of mercury in municipal id waste. Assessed toxicity to mercury given current environmental exposures and under extreme scenarios. Studied mechanisms of bioaccumulation of mercury in fish. Municipal solid waste: Performed or participated in several in-depth assessments of risk ajssodated with management of municipal solid waste. Developed and applied ex associated with ahborne emissions from waste-to*energy plants landfills. Applied technical knowledge to criticism of various prop concerning landfills, wasle-to-energy plants, and mixed waste iseonjrisks from solid waste regulations ts designated as Superfund sites. Food microbiology and food toxicology Served as expert toxicologist in matters involving saimonelosts fror i ingestion of poultry, alleged salmonellosis from Ingestion of eggs, and related incidents. Served as consultant to National Academy of Sciences, Saccharin and Food Safety Pokey. Developed relative risk a additive uses of nitrite In cured meats; quantified and balanced nitrite absent from food product) against risks of cancer (from N-rii for a Study of 4 for the food of botulism (were compounds from during cooking In the presence of nitrite). Cambridge Environmental toe m56 Chariot Straw Cvnbridys MaHsehumos 02141 617*229*0010 817*229*0113 UCC 075734 Laura C. Green, Ph.D., O.A.B.T. Page 4 Selected project experience (continued): Miscellaneous risk assessment and risk communication Participated in scores of public hearings on various matters of envti onmental health and safety. Presented testimony on general toxicologic matters, as wel as on specific aspects of waste water discharges, pesticide applications, and won place exposures to various chemicals. Attempted throughout to be precise and detune lt yet understandable to audiences with disparate backgrounds and biases. " OTHER PROFESSIONAL ACTIVITIES: Invited peer reviewer, Epidemiology Invited peer reviewer, Agency for Toxic Substances and Disease Registry Invited member, Visiting Committee, Whitaker College of Health Sciences and Technology, M.l.T. Invited lecturer in Toxicology, Harvard School of Public Health PROFESSIONAL ORGANIZATIONS: American Association for the Advancement of Science American Chemical Society Society of Toxicology ORIGINAL REPORTS: Lash, T.L. and Green, LC. (1992). Bank reflex measurement of effects of trichloroethylene exposure on the trigeminal nerve. Letter to Editor. Muscle and No In Press. Crouch, E.A.C., Green, L.C.. Jaffa. D.. Lash, T.L., Luis, SJ., and Pile Interim report on an assessment of risks to health potentially , M.B.G. (1992). ted with exposure to OH 55 tltat may leak from a Myers submersible pump in a water w Cambridge Environmental Inc. Green, LC., Waklman, R.H., and Golan, D.E. (1992). Comment on the srpretatlon of lymphocyte phenotyping. Cancer Immwol Immunother ?$:2ia-2 Cambridge Environmental Inc S8CMHMSM CimorwpiMtsuenusffts 02141 017*228*0810 017*223*0819 BW UCC 075735 Laura C. Green, Ph.D., D.A.B.T. Page5 ORIGINAL REPORTS (continued): Zemba, S.G., Pilkington, Crouch, EAC, Armstrong, S.R., Jaffa, D Lash, T.L., and Green, LC. (1992). A health risk assessment of the waste-to-enw^ plant proposed for Green Island, New York, Cambridge Environmental Inc. Zemba, S.G., and Green, L.C. (1992). Perspectives on mercury. Solid Wafoe and Power 6(31:38-44. DeVoto, E., Green, L.C., HirschfieW, D.J., Lash, T.L, and Zemba, S.G. A qualitative assessment of potential health effects associated with airborne emi* from the proposed waste-to-energy facility in Lisbon, Connecticut Cambr Environmental Inc. Crouch. E.A.C., DeVoto, E., Green, LC.. and Zemba, S.G. (1991). Phase risk characterization tor the USM site, Beverly, Massachusetts, Cambridge Environments Inc. Armstrong, S.R., Crouch, EAC., DeVoto, E, Green, LC., and Lash, T.L ( 990). Comments on the ATSDR's draft health assessment guidance manual, Cambridge Environmental Inc. Zemba, 5.G., Crouch, E.A.C., DeVoto, E., Green, L.C., and Pilkington. M.B 3. (1990). Phase II risk characterization for Chelsea Tank Farm, Chelsea, Massachusetts, Cambridge Environmental Inc. Croy. R.G. and L.C. Green (1990). Analysis of health hazards from soils Staining vanadium, Cambridge Environmental Inc. Crouch, E.A.C., DeVoto, E., Green, LC., and Zemba, S.G. (1990). A heeilll risk assessment of the proposed East Bridgewater integrated waste-disposal system, Cambridge Environmental Inc. Crouch, E.A.C., Green, LC., and Zemba, S.G. (1990). Estimation of heakjtli rtek from landfill gas emission. Proceedings of tie GRCDA 13th Annual International LandfW Gas Symposium, Lincolnshire, IL, p. 87-94 Crouch, EAC., DeVoto, E., Green, LC., and Kaden, DA. (1989). Comnw ts on U.S. EPA's proposed national emission standards for hazardous air pollutantsj--| benzene waste operations, Cambridge Environmental Inc. Cambridge Emriroameittal Inc SSChwmSVMt femMte MatuehuMns 02U1 617*229*0610 617*226*6613 MX UCC 075736 Laura C. Green, Ph.n., O.A.8.T. Page6 ORIGINAL REPORTS (continued): Crouch, E.A.C., Kaden, D.A., Green, L.C., and Lash, T.L (1969). Addenpi toj health risk assessment for the W.R. Grace & Co. Property, Cambridge, Massai husetts, Cambridge Environmental Inc. Crouch, E.A.C., Green, L.C., and Kaden, D.A. (1989). Health risk assess* snt for proposed waste-to*energy facility, Orange County, Florida, Environmental Ml and Toxicology Group, Meta Systems Inc. Crouch, E.A.C., Green, L.C., and Lash, T.L (1989). Assessment of heath i is^sdue to perchloroethytene contamination of groundwater beneath Shaw's $ ip^rmarket property, West Street, Brockton, Massachusetts, Environmental Health arvj| fjj:wicotogy Group, Meta Systems Inc. Baer, S.N., Crouch, E.A.C., Green, L.C., and Lash, T.L. (1989). Health Central Street, Norwood, Massachusetts, Environmental Health Meta Systems Inc. characterization, 211 Toxicology Group, Green, L.C. and Lash, T.L (1989). Response to the NCTR technical r< fpr experiment number 338: bioassay of Gentian Violet in flacher 344 rats, Enviroi impntal Health and Toxicology Group, Mata Systems Inc. Green, LC. and Lash, T.L (1989). Response to the NOTH technical r number 304: B6C3F1 mouse btoassay of Gentian VtoteL Envir Toxicology Group, Meta Systems Inc. tor experiment al Health and Crouch, E.A.C.. Green, LC., and Lash, T.L (1989). Comments on f proposed in the national contingency plan. Environmental Health Meta Systems Inc. studies as Toxicology Group, Crouch, E.A.C., Green, L.C., and Lash, T.L (1989). Comments on ERA proposed revisions to the hazard ranking system. Environmental Health and Toxicology roup, Meta Systems Inc. Crouch, E.A.C. and Green, LC. (1989). A protocol tor estimating ambtoM air concentrations from area sources for site risk assessment Environmental Health andjlj urology Group, Meta Systems Inc. Cambridge Eitriroomeatal lac 56 Chariot Streot Cambridge Massachusetts 02141 617*225*0610 017*225*0613 MX UCC 075737 Laura C. Green, Ph D., D.A.B.T. Page 7 ORIGINAL REPORTS (continued): Green, l.C. and Lash, T.L (1989). Response to NCTR technical report 305, 354, and 355: Three generation reproduction and toxicity studies of Gentian Vk et i flscher 344 rats, Environmental Health and Toxicology Group, Meta Systems Inc. Crouch, E.A.C., Baer, S.N., Kaden, D.A., and Green, LC. (1988). Health ^ k Characterization for parcel 3, Cambridge Center, Environmental Health and Toxicology! (! roup, Meta Systems Inc. 111 Baer. S.N., Crouch, E.A.C., Green, LC., and Lash, T.L. (1908). MunicipiJ w Dlid waste landfilling: A review of environmental effects, Environmental Health and Toxicol >gy Group, Meta Systems Inc. pharntey, G,, Crouch, E.A.C., Green, L.C., and Lash, T.L (1988). ComrT^jtts on the ERA'S proposed drinking water regulations, maximum contaminant level tic its and national primary drinking water regulations for lead and copper S3 FR 31516J Environmental Health and Toxicology Group, Meta Systems Inc. Conner, M.W., Crouch, E.A.C., Green, LG., and Lash, T.L (1988). An asai sament of the safety of grade A shett eggs, Environmental Health and Toxicology Group, rieta Systems Inc. Green, LC.. Lash, T.L., MainviNe, C., and Menzle, C. (1968). Preliminary a isessment of the environmental quality surrounding the Saugus RESCO landfill, Environmental Health and Toxicology Group, Meta Systems Inc. Green, LC. and Lash, T.L. (1968). Comments on the ATSOfl toxicological profile for lead. Environmental Health and Toxicology Group, Meta Systems Inc. Crouch, E.A.C., and Green, LC. (1988). Health risk assessment for the W, L Grace & Company property, Cambridge, Massachusetts, Environmental Health and Tf^fcdlogy Group, Meta Systems Inc. Green, LC., Kaden, O.A., Lash, T.L, Tamenbaum, S.R. g j|, (1988). ctai ments on the ATSOR toxicological profile lor trichloroethylene, Environmental Health and i oxicoiogy Group, Meta Systems Inc. Green, LC. and Lash, T.L (1987). Response to two teratology studies: teratologic evaluation of Gentian violet in CD rats, 2) teratologic evaluation of Gentian \J<i et in New Zealand white rabbits, Environmental Health and Toxicology Group, Meta Kerne Inc. Cambridge Environmental toe ss ciwiM Stmt CamMdQi Mataacnusecs 02M1 017*229*0810 817*229*4813 HW UCC 075738 Laura C. Green, Ph.D., D.A.B.T. Page 8 ORIGINAL REPORTS (continued): Green, l.C. and Lash, T.L. (1907). Response to two 90 day studies: 1) 90 lay study c4 Genten Violet in B6C3F1 mice, 2) 90 day study of Gentian Violet in fischer 3*4 rats. Environmental Health and Toxicology Group, Meta Systems Inc. Baer, S.N., Crouch, E.A.C., and Green, LC. (1987). A toxicologic analyst of apple-processing and related sludges applied to field corn croplands. Environmental Heahh and Toxicology Group, Meta Systems Inc. Crouch, E.A.C., Menzie, C., and Green, L.C. (1987). A commentary on superfund program: Interim guidance on compliance with appropriate requirements', Environmental Health and Toxicology Inc. U.S.E.P.A's or relevant and bup, Meta Systems Green, LC., Lash, T.L., and Crouch, EAC. (1987). Alternatives for munib tal waste disposal, Environmental Health and Toxicology Group, Meta Systems Inc. ! I Green, LC. and Baer, S.N. (1987). Assessment of the safety of lead in ipdnerator ash. Environmental Health and Toxicology Q'oup, Meta Systems tnc. Crouch, E.A.C. and Green, L.C. (1987). A reevaluation of ihe public heap nrisk assessment for the proposed Boston Resource Recovery FacSfty, Environmental ^|alm and Toxicology Group, Meta Systems Inc. Green, LC. (1986). A commentary on the draft carcinogen policy' Department of Public Health on August 26,1988, Environmental Group, Meta Systems Inc. y (he Massachusetts and Toxicology Green, LC. (1986). Gentian Violet: A review of the scientific evidence. $ rironmental Health and Toxicology Group, Meta Systems Inc. Green, LC., Baer, S.N., EAC., Crouch, Foster, S. (1988). A critique of I# Massachusetts Department of Environmental Quality EntfneeHng (DEQE) ambient rirjguidelne for polychlorinated tfbenzo dioxins and fcirana (PCoDs and PCDFs), ivkonmental Health and Toxicology Group, Meta Systems Inc. Green, LC. (1988). Allergic response to formMdshyda, Environmental Hbj Hh and Toxicology Group, Meta Systems Inc. caaaonogs cnwrowiioiiBi bib SSChariMStmt CmWrWoi. MxMirhntti 02141 617*225*0010 sf7229-ieiamx UCC 075739 Laura C. Green, Ph.D., D.A.B.T. Page 9 ORIGINAL REPORTS (continued): Graham, J.D., Wifcox, M.A., Green, LC., Roberts, MJ. (1986). Formaldehyde and cancer riskAn evaluation ol governmental risk assessments, Department of hjeulth Policy and Management, Harvard School of Pubtic Health. Green, L.C. (1986). Carcinogen-DNA adducts; Significance and detect! particular emphasis on nitro-substituted pyrenes, Environmental I Meta Systems tnc. n human tissues with i tth Toxicology Group, Skipper, P.L., Green, L.C., Bryant, M.S., and Tannenbaum, S.R. (1984). ng exposure to 4-aminobiphenyl via blood protein adducts. IARC Scientific Public 008. 59:143-150. Green, L.C., Skipper, P.L., Turesky, R.J., and Tannenbaum, S.R. (1964), 4-aminobiphenyl via a cysteine adduct In hemoglobin, frfngar vivo dosimetry of 44:4254-4259. Green, L.C. and Tannenbaum, S.R. (1982). Nltate and nitite in food. VIII(5):1-6. i and the M.D. Green, LC., Tannenbaum, S.R., and Fox, J.G. (1982). Nitrate in human p canine milk. Letter to New England Journal of Medicine 306:1387*1368. Green, LC. (1980). Metabolism of narate. In Procaedngs of the Meat Conference, American Meat Institute. stry Research Tannenbaum, S.R. and Green, LC. (1961). MettboWam of nfeate. In ointesQnai Cancer: Endogenous Factors, Banbury Rsport No. 7, Cold Spring Harbor falory, p. 331-341. Green, LC., Rui2 de Luzuriaga, K.f Wagner, DA, Rand, W., istfan, N., Y Tannenbaum, S.R. (1981). Nttrate biosynthesis in man. Proceed! Academy of Sciences, USA 87:7784*7788. L V.R, and of the National Green, LC., Tannenbaum, 3.R., and Goldman, P. (1961). NNrate synthst* in the germfres and conventional raL Science 212:56-68. Mergens, WJ., Vane, F.M., Tannenbaum, S.R* Green, LC., and Skipped, .L (1979). In vitro nitrosatfon of methapyrHene. Journal of Phampcoioolcal Science 58:827-832 Cambridge Eovtroaneatal toe 38 CtisriM Straw 817*223*0810 817*229 MX 02M1 UCC 075740 Wit Laura G. Green. Ph.D., DAB.T. Page 10 ORIGINAL REPORTS (continued); Baldwin, J.E., Scott, A., Branz, S.E., Tannenbaum, S.R, and Green, UC. (1078), Chemical sludtes on carcinogenic nitrosamines. i. Hydrolysis of a-ao iynitrosamines. Journal of Organic Chemistry 432427-2431, Hansen, T.J., Iwaoka, W.T., Green, LC.t and Tannenbaum, S.R. (1977). Analysts of N-nitrosoproline in raw bacon; Further evidence that nttrosoMine is not a major precursor of mtrosopyrroHcflne. Joumaf at Aipfcputtiae Foofl 25:1423-1426. Green, L, Hansen, T.J., iwaoka, W.T., and Tannenbaum, S.R. (197 systems for the chromatographic analysis of nltrosamJnea. p| International Symposium on Nitrite in Meat Products. Zaial. ~ p. 145-153. Speckle detection of the 2nd Wageningen, eds., DOCKS AMO DOCK Cl lAPTEflS: Graham, J.D., Green, L.C., and Roberta, M. (1968). tn Search of__ Cancer Risk. Cambridge, Massachusetts, Harvard University Chemicals and CoidHz, GA, Stampfer, M.J., and Green, L.C. (1988). Dietary in variations in SusceptWtvlo inhaled Polyols: Jstsffl implications. J. Brian. B. Beck, AJ. Warren, and R. Shafch, Hopkins University Prase. ol lung cancer risk. Mechanisms, and Policy iaftfmore; Johns Green, LG., Rak, 0., and Tannenbaum, S.R. (1982). Nitrate, nitrite, and N-nltroso Compounds; biochemistry, metabolism, toxicity and cardnogenidty. In Hum^'ihjtritkm: Current Issues and Controversies. A Neuberoer and T.H. Jukes, eds. ister, England: MTP Press Limited, p. 87-140. MChwtuSM CimMrtn MMMdwMBt 02141 817*229*0810 6t7*229*teis X UCC 075741 02 '93 10:01 ENV MET' *NC USA P.2/16 RUDOLPH X JAEGER PnM and Friadpnl ScfcMfct MdimIiI Mediae, Ir 263 CM Awm WeXwoad, Nov Josq (7475 professional history Environmental Medicine, Inc. (1985 - Present) New York University Medical Center, Institute of Environmental (1983 - Present) New York University Medical Center, Institute of Environmental Environmental Medicine (1979 - 1983) Harvard School of Public Health - Visiting Lecturer on rwnp--^nai (1979 - Present) Harvard School of Public Health - Associate Professor in Toxicology Harvard School of Public Health - Assistant Professor in Toxicology Harvard School of Public Health * Research Associate in Toxicology Research Professor * Associate Professor in ronmental Toxicology EDUCATION Phi)., Biochemical Toxicology - Johns Hopkins University, School of Hyi B.S., Biology * Rensselaer Polytechnic Institute, 1966 AFFILIATIONS and Public Health, 1971 Society of Toxicology Society of Toxicology of Cauda American Academy of Clinical Toxicology American Industrial Hygiene Association American Conference of Governmental Industrial Hygienists American Chmnical Society American College of Toxicology American Association of Pathologists American Association for the Advancement of Science Sigma XI (Harvard - RadcUffe Chapter) Middle-Atlantic Section, Society of Toxicology Toxicology Forum (Individual Member) inhalation Toxicology Specialty Section, Society of Toxicology Society fix Risk Analysis Amariev Society for Testing and Materials APPOINTMENTS Toxicology InfonnatioQ Prognan Committee, Board on Environmental Stud) Mi fend Toxicology, Nxiooal Academy of Sciences - National Weaexrti Council HONORS Research Career Development Awwd, National Institute ofEnvironmental 1978 - 1983 Leslie Silverman Award, New England Section, American Industrial Hy UCC 075742 SEP 02 "93 10506 ENV MET USA P.3/16 Dr. Rudolph J. Jaeger Curriculum Vitae EDITORIAL SERVICE September 2, 1993 Page 2 Editorial Boards: Journal of Toxicology and Environmental Health | Journal of the American College of Toxicology Boston Bulletin on Chemicals and Disease (10K5| NYU Medical Center Health Letter (advisory) ]| | Environmental Contractor Magazine LICENSURE AND CERTIFICATION Certification: Diplomate, American Board of Toxicology Registered Environmental Assessor (REA) State of California Board Eligible: Professional Standards Review, American Academy of Toxicological Sciences American Board of Industrial Hygiene Toxicologic Aspect^ of Industrial Hygiene INVITED LECTURES AND PRESENTATIONS American Lung Association, Boston, MA * Toxicology of Pesticides Defense Research Institute, Boston, MA - Review of Immunology Harvard School of Public Health, Boston. MA - industrial Hygiene co Chemical Accidents; Epidemiology and Risk Assessment for Lawyers; T Massachusetts Department of Public Health ency Planning for Review course for Bell Communication! Research, Piacauway, NJ - Worker Rigfti-To-Know; lizard Communication Training ! Clark University, Worcoter, MA - Toxicology i j jUniversity of Rhode Island, Kingston, R1 - Inhalation Toxicology Methods John B. Pierce Foundation of Yale University, New Haven, CT - Plastics Ti Hunter Cottage, Manhattan, NY - Toxicology Seminar New York Stale Division of Laboratories, Albmy, NY - Tc AT&T Bell Laboratories, Murray HilL NJ and Lisle, IL - Toxicology Kevb US Department of Justice, Assistant Attorneya-General - Training Masting on Litigation. and Toxic Tort UCC 075743 SEP 02 '93 10:07 ENV PCr TNC USA P.4/16 Or. Rudolph J. Jaeger CnrrtcnhiiM Vitae CONSULTATIVE EXPEDIENCE September 2, 1993 Page 3 Children's Hospital, Boston Blood Preservation Laboratory - Analytic Boston Poison Control Information Center * tommihuM and lecturer s Itant General Tire and Rubber Company, Akron, OH - Analytic Energy Resources Company, Cambridge, MA - r^ncnirmg Toxicologist Office of Regional Solicitor, U.S. Department of Labor, Philadelphia, PA - . wit Witness Toxicology ofKepone Hundley, Taylor and Class, Richmond, VA - Consultant to Plaintiff - Tc Polaroid Corporation, Cambridge, MA - Consulting Toxicologist logy of Kepone National Institutes of Occupational Safety and Health - Review Consultant, C itecia Document of Vinyl Monomers 1 National Academy of Engineering, NAS-NRC - Panel Membff, Subcommftt^p on Flammability of Dielectrics U.S. Department of Labor OSHA * Expert Witness, Styrene U.S. Department of Labor OSHA - Expert Witness and Toxicology Consultant on Dimethyl Aminopropionitrile (NIAX ESN) Boston Poison Control Center and United States Coast Guard - Consultant Hygiene of Phosphine Toxicology and Industrial Environmaktal Protection Agency, Cincinnati, OH - Criteria Reviewer and C- mmittee Member, Water Quality Standards Division Geoeral Electric Company, Schenectady, NY - Lecturer an Toxicology Environments! Protection Agency, Washington, DC - Criteria Document Acrylonitrile, Trichlorethyieoe, Perchlorocthylcnc VmyHdsne Chloride, Clement Aaaocaat--, Washington, DC - Quality Assume* Review Panel, tent Review Occupational Health Services, lne^ Cambridge, MA - Consultant Metropolitan Life huuranca Co., New York, NY - Consultant Clement Associates, Washington, DC and CEQ Review Consultant, Huim^ Reproductive Toxicity, Council on Environmental Quality World Health Organisation International Program on Chemical Safety, HeUi Id, Finland - Expert and Rapporteur, Criteria Document Task Group, Styrene Health Effects ! UCC 075744 3tr Utf. U:U7 NV MED INC USA P. 5^1.6 Dr. Rudolph J. Jaeger Cnrricuhim VlUe American Cyanamid Co., Wayne, NJ - Consultant September 2, 1993 Page 4 Goodwin, Procter and Hoar, Boston, MA - Consultant to Defendant and Expert Witness on Perehloroethyiene Life Systems, Inc., Cleveland, OH and Office of Toxic Substances, Consultant and Expen Witness, Structure Activity Relationships Patterson, Bellknap, Webb and Tyler, New York, NY - Consultant Hale and Doit, Boston, MA - Consultant and Expert Witness Mueller's Macaroni Co., Jersey City, NJ - Consultimt 'A, Washington, DC - Attorney-General, State of New York Consultant to Plaintiff Expert Metals and Organics Southern California Edison Co., Rosemead and Visalia, CA - Consultant and Expert Witness, Creosote, Pentachlorophenol and Dioxins | Karch and Associates, Washington, DC - Consultant it USEPa and US Department of Justice, Washington. DC and Niagara Fails, N)' - Consultant to Plaintiff, Expert Witness, Superfimd US v. Honker Chemical Co. | Plymouth Rubber Co, Canton, MA - r-nfMwhn* on Safety Evaluation C< Product Environmental Research and Technology, Concord, MA - Consulting Toxi Air Toxics Programs - Risk Assessment on Ground Water and Combustion Engineering, Windsor, CT - Consulting Toxicologist on Ground Water Electric Power Research Institute, Palo Aho, CA - Document Reviewer on Health Effects of PCBs and Dioxins Albert Orgain, IV Esq., Richmond, VA - Consultant Essehe Letraset Manufacmring, Moonacfaie, NX - Consulting Toxicologist in Supplies and Inks Labeling, Art New Yoric Telephone Co., New York, NY - Consulting Toxicologist Environmental Research Technology and Coonecticnt Busineat and Consulting Toxicologist on Air Toxics Regulations Hartford, CT - GelUfent ft Co., London, England * Product Registration, PMN and Toxicology US EPA Environmental Criteria and Assessment Office, Ciodimsti, OH 4 Toxicology and Effects Ranking 1' on Biochemical William Casagrande, Case Market, Bergonflcld, NJ - Food Safety Review on Sinoked Meats UCC 075745 - Uti iJ Spp 02 '93 10^08 ENV fCr "NC USA P.6/16 Dr. Rudolph J. Jaeger Curriculum Vitae September 2* 1993 Page 5 Penobscot Energy Resource Co., Omngton, ME - Review on Health El Incineration >f Municipal Solid Waste Wadleigh Low Finn, Manchester, NH - Health and Safety - Galvanized until pipes for drinking water Gardere and Wynne, Dallas, TX - Wood Preservation Chemicals and Soil ation Goodwin, Procter and Hoar, Boston, MA - Document preparation for Perchloroethykne Advisory Board on Remediation Technology, Isa., Pittsburgh, PA - Devefopnent of Health Disposal Site Safety Plan for Waste Womble, Carlyle, Sandridge and Rice, Winston-Salem, NC - Toxicology Cot sultant Jones, Day, Reavis and Pogue, Washington, DC - Document Service Esselte letraset UK London, England - Consultant on Product Labeling f^oibss Importation Ropes and Gray. Boston, MA - Toxicology Consultant Union Carbide Corporation, Law Department, Danbury, CT - Toxicology Consultant Goodwin, Procter and Hoar, Beaton, MA - Toxicology Consultant Lord and Taylor, New York, NY - Toxicology Consultant IBM Corporation, Armonk, NY - Toxicology Consultant Southern California Edison Co^ Venice, CA * Air Pollution and Hazardous W|aste Risk Assessment Greenberg, Dauber and Epstein, Newark, NJ - Toxicology Consultant Hackensack Water Co_, Harrington Park, NJ - Document Review on NJ W^toj Quality Shaheen, Cappiello, Stein and Gordon, Concord, NH - Toxicology Consultant State of Michigan, Department of Natural Resources, IAnalog, MI - Toxicology Consultant, Special Advisory Committee on Methyl Chloroform Monsanto Agriculnni Company, St Louis, MO - Toxicology Consultant Walton, tjwnrff, Schroeder mtd Canon, Miami, FL - Toxicology Consultant Akin, Gump, Strauss, Hauer and Feld, Washington, DC - Toxicology William* & Connolly, Washington, DC - Toxicology Consultant AMAX Mineral Resources, Inc., Golden, CO - Toxicology Consultant UCC 075746 SEP 02 '93 10:08 ENV PC* NC USA P.7/16 Dr. Rudolph J. Jaeger Curriculum Vitae Griffith ft Burr, Philadelphia, PA - Toxicology Consultant September 2, 1993 Page 6 Hyperion Catalysis International, Lexington, MA - Toxicology Consultant, p oduct Registration Ryan, Ryan and Hickey, Stamford, CT - Toxicology Consultant Fon Lee Board of Education, Fort Lee, HI - Toxicology Consultant, Astxstc t Hazard Evaluation Palisades Park Board of Education, Palisades Park, Ni > Toxicology Consultant, Asbestos Hazard Evaluation 11 Ridgewood Board of Education, Ridgewood, NJ - Toxicology Consultant, A: >estos Hazard Evaluation McGuire Woods Battle and Booth, Richmond, VA - Toxicology ftnunw^ Kehoe, Doyle, Pleyter and Novick, Boston, MA - Toxicology Consultant Sidley and Austin, Hew York, NY - Toxicology Consultant Griffin, Rainwater and Draper, Crcssett, AR - Toxicology Consultant Gubman Sitomer Goldstein and EdUxz, New York, NY - Toxicology r^infaUr Schoeman, Marsh, Updike and Welt, New York, NY - Toxicology Consuttu t Alter and Hadden, Cleveland, OH - Toxicology Consultant I Smith, Helms, Mnlliss and Moore, Greensboro, NC - Toxicology Consults it Holme Roberts and Owm, Denver, CO - Toxicology Consultant j Lockheed Aeronautical Systems Co., Burbank, CA - Toxicology Consults:! Electro Signal Lab, Faraippuy, NI - Toxicology Consultant | Diamond and Associates, Montpelier, VT - Toxicology Consultant Scanlon, HowIcy, Scanlon and Doherty, Scranton, PA - Toxicology Consultant Envirosphere Co* Lyndhunt, NI - Toxicology Consultant Polymeries Inc., Waltham, MA - Toxicology Consultant Holknd and Hart, Billings, MT - Toxicology Consultant Environmental Project Control, Grafton, MA - Toxicology Consultant TeiUer ft Taitkr, New York, NY - Toxicology Consultant Mima, Levin, Cohn, Ferris, Giovsky ft Popoo, Boston, MA - Toxicology c| uuttaat UCC 075747 SEP 02 '93 10509 ENV ft < USA P.8/16 Dr. Rudolph J Jaeger Curriculum Vitae Decart, Inc., Momsviile, VT - Toxicology Consultant September 2, 1993 Page 7 Lascaux Farbenfkbrik, Bruttisellen, Switzerland - Toxicology Consultant McCarthy, Gaynor A Gatlin, Framingham, MA - Toxicology Consultant H. Schraincke A Co., Erkraih, Germany - Toxicology Consultant Ice Miller Donadio A Ryan, Indianapolis, IN - Toxicology Consultant Tommasino A Tommasino, Boston, MA - Toxicology Consultant Graphic Arts Systems, Ino, Cleveland, OH - Toxicology Consultant Craft House Corporation, Toledo, OH - Toxicology Consultant i Rupert, Gibbon A Spider, Healdsburg, CA Toxicology Consultant i | Gjevre, McLarnan, Hannaher, Vaa, Skatvold A Mclaman, Moorhead, MN i Toxicology Consultant Tester Corporation, Rockford, IL - Toxicology Consultant Gick Publishing Inc, Irvine, CA - Toxicology Consultant Paint Specialties Laboratory, Portland, OR * Toxicology Consultant Draper Laboratory, Cambridge, MA - Toxicology Consultant Transflock, Inc., New York, NY - Toxicology Consultant W.R. Grace Company, Cambridge, MA - Toxicology Consultant Drinker Biddle A Raath, Philadelphia, PA - Toxicology Consultant AIkon A Rhea, St. Croix, USVT Toxicology Consultant Appleton Paper Company, Appleton, WI - Toxicology Consultant Law Offices of Thomas D. Dolan, Lynn, MA - Toxicology Consultant Cal Western Paints, Santa Fe Springs, CA - Toxicology Consultant Convenience Products, Fenton, MO - Toxicology Consultant Neighborhood Clemen Association, New York, NY Toxicology Consultm Alexander Art, Salem, OR Toxicology Consultant Curley A Curley, Boston, MA - Toxicology Consultant UCC 075748 SEP 02 '93 10:09 ENVlCT < USA P.9/16 Dr. Rudolph J. Jaeger Curriculum Vittt Norman* Hanson A DeTroy, Portland, ME - Toxicology Consultant Fulbrisht A Jaworski, Houston, TX - Toxicology Consultant Osborn, Hiner A Lisher, Indianapolis, IN - Toxicology Consultant O'Melveny A Myers, Los Angeles, CA - Toxicology Cnmgihnt Medea Co,, IncH Portland, OR - Toxicology Consultant Shaft A Shcft, New York, NY * Toxicology Consultant Skyline Corporation, Elkhart, IN - Toxicology Consultant Coffield Ungaretti A Harris, Chicago, L - Toxicology Consultant Kenner Products, Cincinnati, OH - Toxicology Consultant Hasbro, Inc, Pawtucket, RI - Toxicology Consultant Milton Bradley, Inc, East Long Meadow, MA - Toxicology Consultant Taylor Anderson A Ttavera, Boston, MA - Toxicology CAnnhawt Capehart A Scatchard, Mount Laurel, NJ - Toxicology Consultant Kirby A Govemo, Boston, MA - Toxicology Consultant Hays, McConn, Rice A Pickering, Houston. TX - Toxicology rntmhnnr Crowe A Day, Lot Angela*, CA - Toxicology Consultant Ranger Industries, Ttrrton Falls, NJ - Toxicology Consultant NaarDar/KC, Overland Pwk, KS - Toxicology Consnitanr Healy A Healy, Boston, MA - Toxicology Consultant Gallagher A Gallagher, Boston, MA - Toxicology Consultant Moon A Van Alta. Raleigh, NC - Toxicology Conaultmt Franklin International, Columbus, OH - Toxicology Consultant American Plastic Toys Inc, Walled Lake, Ml - Toxicology Connihant Bird, Manila, Boxar, Walpert A Mata; Los Angeles, CA - Toxicology KightKnger A Gray, Indianapolis, IN - Toxicology Consultant September 2, 1993 Page 8 UCC 075749 SEP 02 '93 10J09 ENV fCD TNC USA Dr. Rudolph J. Jaeger Curriculum Vitae P.10/16 l ,September 2 1993 Page 9 American Art A Color, Princeton, NJ - Toxicology Consultant Bums A Levinson, Boston, MA - Toxicology Consultant Frisch Dudek Ltd., Milwaukee, WI - Toxicology Consultant Kaylin Products, ML Any, MD - Toxicology Consultant Sprayon Products, Bedford Heights, OH - Toxicology Consultant Straight Edge, Brooklyn, NY - Toxicology Consultant [ UCC 075750 6EP 02 '93 10:10 ENV fCD INC USA P.11/16 Dr. Rudolph J. Jaeger Curriculum Vitae PUBLICATIONS AND EXPORTS September 2, 1993 Page 10 Barrow, C, A Jaeger, JL (1983), Letters to the Editor - re. "Respiratory and mitabolk response of rats and mice to formalin veacptor"". Toxicologevy. 28. 3S7.-3S9. .1 Bates, IU Bingham, E^ Borek, C-, Brown, U, Cornish, K EL, Crump, K. ;>4 Honak, It, Jaeger, R. Jn Legator, M. S* Mehlman, R, Morphy, S. D,, Mnshak, P.t Nelson, N,, A ndennan, F. W. (1985). Workshop to Review the Severity of Effects Ranking Scheme Document EPA, incinnatl Ohio. Bushnell, P. J., A Jaeger, R J. (1986). Hazards to health from environmental tea 1 exposure: a review of recent literature. Vet Hum. TeikoL 28. 255-261. " Cheng, L, A Jaeger, R. (1982). Acrylonitrile Solubility in Homan Blood: Detent Hutton of the Ostwald Partition Coefficient J. AnnL ToxicoL. 18-20. Cherry, J. Johnson, Jaeger, R. J. (1989), Technical Report on Wells G A H Site, Public Document USEPA Region 1. 81 pg. oburn, Massachusetts, Conolly, R Bm A Jaeger, J. R (1977). Ante Hepaiotoxidty of Ethylene and HaloJenated Ethylenes After PCB Pretreatment finr Hlllttl fOrWTti 31. 131-135. !' Conoliy, 8 8,8 Jaeger, R J. (1978). Effects of Cysteine Diethyl Malcate and Acute Vinyl Chloride Hepatotoxteity. Toxicol Anal PharmacoL 338. propane Oxide on Conolly, Jaeger, R J. (1979). Acute hepstoxicity of vinyl chloride and trichloropropreoe oxide, eicthylmaleatc, and cysteine. ToxicoL A^j- Conolly, R 18, Jaeger, 81,6 Sxabo, S. (1978). Acute HepatOtoxJcity of Ethy Chloride, and Vinyl Bromide After Arodor 1254 PretmtmenL Era Mol Path yleac: modification of 523-531. Vinyl Flnoride, Vinyl 25-33. Conolly, R 18, Szabo, S., A Jaeger, R X (1979). Viaytideae fluoride: acute with PCB or phtnobarbttaL Prac. Soe. jar Inariomui Biology and |ieHy in ruts pretreeted 163-169. Cote, L 1*, Bowen, A^ A Jaeger, R X (1983). Induced tolerance to acrylonitrile exposure. Res. Common. Cheat. PatfaU- 43^1*9-172. toxicity by prior Cote, L1*, Bowers, A Jaeger, R X (1984). Effects of acvytonttrlle on time in rat, mouse, and hamster. Has. Comma* Cham- Patmu ^507 thlone concentrations Eschenroeder, A*, Jaeger, R J* Ospital, X X, X Doyle, C P. (1986). Health! ri ik analysis of human exposures to soil amsnded with sewage sludge contaminated with potychloriaato I dibenzodioxins and dibenaoliarnns. -- 21 435-441. 'i :i Jacobson, M. S* Button, L. ft, Watson, W. H, Berwick, B. L, Jaeger, BL X Kevy, S. V. (1975). Physiologically Solubilized IH-2-Etkythexyt PhthalaU and Us Effect on the l^t|i Monkey: A1 Preliminary Report Toxicol Ann! Pharmacol. 33. 168-169. Jacobson, M. S., Parkman, R, Button, L. N,, Jaeger, 8 X, A Kevy, S. V. (1974). [The toxicity of human scrum stored in flexible potyvinykUororide containers on human fibroblast eeU -cultures: an effect of di-2-ethylhexyl phthalate. Res. Comm. Chens. PathoL and pfcsyosoL g*. 315-323. UCC 075751 SEP 02 '93 i0:10 ENV MEP INC LEA P.12/16 Dr. Rudolph J. Jaeger CUfTfculMin Yitu September 2, 1993 Page 11 Jaeger. It J. (1975). Vinyl chloride monomer: commean on in hepatotoxicity and interaction with 1,1-dichlorwthylene. Ana IVY Acad Sfr 146, HM51. Jaeger, It J. (1976). Kepone Chronology. Science. 193. 94. Jaeger, H J, (1977). Effect of 14-0ichloroethyleoe Exposure on Hepatic Mitochondria. Ree Cnmmun chem Pathol Pharmacol. 1&_ 93-94. [ Jaeger, It J. (197$). Effect of Hypoxia on the Toxicity of 1, l-Diehloroethyleae or Alcryionitrfle. Toxicnl Anpl PtUPnaCQl 257. Jaeger, ft J. (1979). Time-related variatioo of non-protein snllhydryf concentrations is rat tiasues and human Mood. htArch FflYlrtP f***1*4* fL 141-148. Jaeger, It J. (1981). Carbon monoxide In bouses end vehicles. 57, 860-872. Jaeger, It t A Coffman, L. (1977), Hepatotoxicity of M-Dkhloroethylenm A Pvopoeed Meehaakm. 41. 187-188. Jaeger, It J.,Conolty, 8.8,8 Murphy, 0. S.(1973).Dlaraa] variation of and its correlation with 1.1-dtehloroethykne Inhalation toxicity in rate. Pharmacol 6^ 465-471. utathioae concentration Comm. Cham. Path. Jaeger, ft J., Conolty, R. 8, 6 Marphy, h S. (1974). Toxicity and Btochemlai I Changes in Rat* after Inhalation exposure to 1,1-Dichioroethyieae Bromobanaene Styrene AcTyioattrity or 2-Chlorotoutadiene. ToxicoL AppI. Pharmacol 22i. 81* Jaeger, It J* Conolty, R. It, A Morphy, & 0. (1974). Effect of 18 HR fssl 1,1-dichtoroetbyleae-iadneed hcpatotoxfdty and lethalty in rata. 20. 187-198. ttathlone depietioa on Molecnlar Pathology. Jaeger, It J^ Conolty, L i, 6 Marphy, S. D. (1975). Short-term Inhalation toxicity of hnlogesated hydrocarbons. Arch. Environ. Health. 38. 26-31. Jaeger, R. Conolty, It B* Reynolds, L &, 6 Marphy, S. & (197$). BiO|lmkal Toxicology of Unsaturated Halogeaated Monomers. Environ Health Pcrromfr it 121-128. Jaeger, 8^6 Cote, 1 L. (1983V Eflbct of hypoxia on the acute toxicity of acSjtyi|etotie. Rg rftmn^| nm. PntonL Phn--nl 36. lAS^dM. Jaeger, ft J,, Cote, h t, Rogers, A, E* Silver, B. It, A Szabo, & (1984), AcntoiThxldty of Acrylonitrile; Effect or Diet oa Thane Nonprotete SnUhydryi Coolant and Dhtribntiaa of l-ldc-Aerytonttrite or Its Metabolites. J. Amcr, ColL Toxicol. 93-102. Jaeger, 8th Gearhart, J. M. (1982V Respiratory and atctoboUc raspoass offers and mice to formalin vapor. Toxicology. 25. 299-309. Jaeger, 8 t 6 Gearhart, J. M. (1983V Respiratory mad metebolie response of ra| i end mice to formalin vapor. Toxicology. 28. 357-359. 1 UCC 075752 SEP 02 '93 10:11 NV MT .INC USA P.13/16 Dr. Rudolph J. Jaeger Cnrricnhim ViUe September 2, 1993 Page 12 Jaeger, R. J,, 4 Hites, A. R. (1974% Pyrolytic Evaporation of a Plasticizer from Polyvinyl Chloride Meet Wrapping Film. Bull Environ Cootam TnxicoL 111 45-48. Jaeger, R. J,, Mullen, F. EL, Coffman, L. & Morphy, & D. (1975% Vinyl e hepatotoxicity and its alteration by modifier? of hepatic biotraasformaiioa ia the rat. Med Voi XVq^ 301-308. Jaeger, R. J., A Murphy, S. D. (1973% Alterations of barbiturate action following lU-dichloroethyleiie, corticosterone, or acroleia. Arch, lit. Phannicodvn. Thar.. 20S. 131-292. Jaeger, R. J., Morphy, S. 9^ Reynolds, B. &, Sabo, &, A Moslem, M. T. (19710 Chemical Modification of Acute Hepatotoxicity of Vinyl Chloride Monomer in Rats. Toxicol Anal Pfctri incol. 41. 597-608. Jaeger, R. J,, Ptugge, K, A Sxabo, S. (1980% Acnte urinary bladder toxidty of a mixture; a possible new target organ for propionitrile derivative. J. Environ irethane foam catalyst it, Toxkoy ^555-562. Jaeger, R. J., Reynolds, E. S* Conolly, tL R, Moslea, M. Tn Sabo, S, A Murf by, D. S. (1974% Acute hepatic injnry by vinyl chloride ia rats pretreated with pheaobarbitaL 2] 2L 724-726. Jaeger, KL Reynolds, E. S* Sabo, Moelsn, M. T,, A Morphy, & D. (1975% of Vinyl Chloride Monomer in Pbenobarbftal or Aroeior 1254 Pretreated Rat 33. 133. Iition Toxicity Studies Ami flunaiwl, Jaeger, R. X, A RubIn, J. R. (1970% Ftesdcten from plastic devices: extnetion metabolism and accamnlation by biological systems. Science- 17R_ 46(M62. Jaeger, R. A Rabin, J. R. (1972% Migration of a phthalate ester plasrieiar bags into stored bnman blood and its localisation In human tissues. New Em! polyvinylchloride blood 287. 1114-1118. Jaeger, R. J, A Rubin, X R. 0973% Di-2-cthyihtyi phthalate a concentrates. XllllMfife li_ 107-108. doatamiuaat of platelet Jaeger, R. A Rabin, J. SL (1973% Phthalate ester mateboHem ia the Isolated Xa^ 49-53. fried rat liver system. Jaeger, R. J,, A RnbU, X R. (1973% Extraction loeallnattoa aad metabolism of d k-l-ethylhesylphtbalate from PVC plastic medical devices. Environ- Hfth Potmcl. ^ 95-101. |1 ' Jaeger, R. J., Shoaer, L. CL, A Coffinan, L (1977% 1-lJDkhloraathylane Hepatotoxicity Proposed Mechanism of Action and Dtatribatioa and Binding of Carbon-14 Radioactivity Following Inhalation Exposure In Rati. farlfM HMlffl r^TTfl 21. 113-119. Jaeger, R. J-, Sknraifc, W. A Heiaaan, R. (1902% Thermal decomposition products of PVC plastics: effiatfs on guinea pig long mechanics aad pulmonary mixed faction oridese activity. J- 43. 900-907. Jaeger, R. X, Snmman, R. CL, Gearhart, J. Bowers, A. 8, Shore, R. L, A Repeated pulmonary faactioa evaluation followiag Meomyda treatment. 415423. lakamar, A. R. (1983% Environ. Health.. 11. UCC 075753 SEP 02 '93 10:11 ENV MF~ 7NC USA P.14/16 Dr. Rudolph X Jaeger Curriculum Vitae September 2, 1993 Page 13 Jaeger* R. J., Sabo, S* A Coffman, L. J. (1977). 14-Dichloroethyleae hepatob xicity: effect of altered thyroid function and evidence for the subceUular site of injury. J. T^aI. p.^ ln. Health, i, 545.555. Jaeger, R. J^ Trabulus, M. J,4 Murphy, D. S. (1973). Biochemical effect* or 1.1^iiehloroeUtylene in rats: dissociation of its hepatotoxidty from alipoperoxidativc mechanism* Toxicol. APPl Pharmacol^ 24. 457-467. Jaeger, Weiss, A. (1992). Trichloroethene: Toxicology and Epidemiology A Critical Review of the Literature. In Phantom Risk David Bernstein, Kenneth R. Poster, A Peter W. |H|iher. (Ed*.), MIT Press, Cambridge, MA, 29 pg. Moctea, M T, Jaeger, R. J,, Sabo, S*, A Reynolds, E. S. (1975). Acute Chloride Monomer: Morphologic and Biochemical Effects of Prctreutment with Function Oxidase System. Toxicol AppI Pharmacol. 33. 133-134. lion Toxidty of Vinyl uccrs of Hepatic Mixed Ptugge, H., A Jaeger, R. J. (1979)* Acute Inhalation Toxidty of2 Chloro-1 3 Bt on Liver and Lung. Toxieol AppI Pharmacy 50. 565-572. Cbloroprene Effects Plngge, H., A Jaeger, R. J. (1979). Toxicology or 2-Cfck>ro-2'3-Butadle*e CUortyprene Acute Effects in Liver and Lung After Inhalation Exposure in Rats. Toxieol Anal PhnnnanoL 41 A108. Reynolds, E. S* Jaeger, R. J., A Murphy, S. D, (1^ Acute liver injury by vinj I ehloHdc: involvement of endoplasmic reticulum lu phenobarbttaJ-pretrtated ruts. 11. 227-233. Reynolds, E. S* Molten, M. T,, Boor, P.X,6 Jaeger, It J. (1980). M-Dichlorot thykne hepatotoxicity. Time course of GSH changae and btochemteal aberrations. An. J. PnthoL. 101. 3B1-343. Reynolds, E. Moeteu, M. T., Sabo, &, A Jaeger, R. J. (1975). Vinyl chlorido-I educed deactivation or cytochrome P-450 ad other components of the liver mixed teactloa oxidase systea i: an in vivo study. Res f^flgg Cgem Pathol "unilKlI 12- 685-694. Reynolds, . Motion, M. T., Sxabo, &, Jaeger, E JL, A Mnrphy, S. D> (1975). ifiepatotoxteity of Vinyl Chloride and 14-DichlorocthylW Am J PnthoL 219-236. j Rubin, R. J* 4k Jaeger, R. X (1973). Some Pharaiaeologk and Toxicologic Effects of Di-2-ctbylhexyl PfathaJate (DEHP) and Other Ptasticteen. FiffllrM Hl>Mh Jnn. sLai Shoncr, L. G., Jaeger, R. J., A Mnrphy, S. D. (1976). Distribution of Carbon-14 tn Fed or Pasted Rats. Toxicol Anri PhnrmaeoL 37. 174. SUver, X. a. Sambo, S Cahffl, M* A Jaeger, R. X (1987). Tlme-eonrse Ll-14C]acryfoaitrUe In rate after intravenous admleletration. of the distribution of 386. Skoraik, W. A* Hdmaan, iL, 4k Jaeger, J. R. (1979). Pnlmoanry Merhante* In Ul after Acute Exposure to Plastics Combaatioa Products. Toil uited Guinea Pigs 48. 57. Skoraik, W. An Heiuunn, IL, 4k Jaeger, R. X (1981). Pulmonary mechanics meoeuremeatf using a nonsurgieal eempnterteed method. ToiteoL gninea pigs: Repented 59. 314-323. UCC 075754 .. 1*W P.15/16 UCC 075755 USA P.16/16 V / / / l \ \....v x INCORPORATED- Schedule of Eroforionnl Feca SPCCIAUSTS IN PUBLIC HALTH 263 CENTER AVENUE WESTWOOO. NJ 07675 {200 696*7929 Caweorv Class l1 Class 2 Class 3 lass 4 Hourly Rate Billing Time Increment Depositiona/Testimony $250.00 0.25 hr $500.00* $125.00 0.25 hr $45.00 0.5 hr 5 30.00 c .5 hr Professional fees are billed on a time basis. All charges are portal to partti and travel time is billed at 50%. Reimbursable charges and expenses are billed with 20% oVerhead when prepaid by EMI. Exceptions must be agreed in writing. Examples include, but li ire not limited to, the following: Travel Expenses Library Charges Laboratory Fees Lodging and Meals Data Base Access Sample Preparation Telephone a|ft FAX Outside Messenger Service Sample Coll< Invoices are due on the day they are rendered by Environmental me, Inc. Bills for services are payable within 30 days of the invoke date. After 60 day. except by written agreement, statements will include an interest charge of 2% per mo: any unpaid balance, Accounting is done on a cash basis. Expenses are incurred in advancdi o payment. Rates are subject to change following notice. Please sign and date one copy of ibis fee schedule and return it to our office. Client Acceptance Signature Date Signed Dr. Jaegv and Dr. Domamiri are billed ai the class 1 rets while Ms. Weiss class 2. Adminifirxive stiff is baiWd as class 3; obiml Saff is charged at the class 4 rets. The stted hourly rate is effective during testimony and deposition time in hell day (4 hour) sod flail day (g hour) increments. Depositions which extend peat this time an billed in hill hour increments. Federal Tax Payer ID Number 22-2685270 Printed on September 2, 1993 pax (9Qi) eae^iie tty; <aoi> are area UCC 075756 .u.......