Document MJbnVYV7qKqjQNBgmQn0qg0nk

HASKELL LABORATORY FOR TOXICOLOGY AND INDUSTRIAL MEDICINE DATE August 17, 1777 TO: DR. ROBERT SALSMI PIGMENTS DEPARTMENT TITLE: MEDICAL RESEARCH PROJECT MR- 2929 PART I CHRONIC INHALATION TOXICITY STUDIES ON Ti02 AND TiCl^ 0 Authority is requested to undertake the investigation identified above and described as follows: This proposal is written to cover the costs of chronic inhalation toxicity .studies on Ti02 and TiClh in rats. A detailed protocol and cost estimate is attached. The cost estimate below is based dn 3 test levels/compound and a common control group exposed for approximately 18 months (followed by a. 6-month holding period). If exposure beyond IS months is necessary, a Part II to this project will be written. A c6st es.timate"for an additional six months' exposure is included in the attachment. Amount requested $667.170_____________ ` Previously authorized0___________________ Expended to date Account to be charged___________________ Work to be started 1st Quarter 1979 Request for study made by d-?swissions between R. Salemi and Haskell personnel, June 1977 If this request meets with your approval, please enter the account to be charged, have two copies authorized and return than to llaskell Laboratory,