Document MJ4LODga4ZQKBw8ZxdnYKgwGk

-.. Geniome msinneus 3IMMCCo~nnstcer SL Paul, MN 55144-I000 612733 lllO BM ~]~ r1i 5.5 May 15, I998 BBYYCCEERRTTIIFFIIEEDDMMAAIILL DoDcoucummenenttPProrcoecsesssiinnggCCeenntteerr((77407)) AAttttan:: SS.e~e ioncS((eet )) CCoi ooorrddo iinnaatn toorr OfficeOf ToricSubsascs Otfize OfToxic Sub~tan~ United States Environmental Protection Agency 401M ter,Souther 401 M Street, S~uthwest Wasingon, D.C.2060 Washington, D. C. 20460 Re: TSCASection 86) PetorsaSuilfaatnee Re: TSCA Section 8(e) -- Perfluorooctane Sulfonate Docket Numbers SERG-18037% SERQ 130576 Docket Numbers 8EHQ-IIS0-373; SEHQ-1180-374; S 8EHQE-03H 81-03O 94 -O81-034 DescSitMadan: . Dear S~r/Madam: p With thst, 3MCompany sbi fotototeEPAAdisstros puss 0 With this letter, 3M Company is mbmitting information to theEPA Administrator pursuant to OCe ACAAs Section 8(e) ofthe Toxiz Substances Control Azt ("TSCA"). As detailed below, this information te tn oroehnil peifcaly, pacslooat(aFFOnS" (CNo A2755S35. 3r3)e]la-=taeansndtdoccofolnunsoisrissottcsshooeffmaanincazalllyysssi-issosopffebbclilfooiocoaddsllseyer,raapsesaramfmlpuploelresossoshchtooswnwieinnsggulPPfoFFnOOaStSaeatCtvTveeFrrOyySllo'o3ww[(C(iL.Aee.S,,pNparoat.~s2pp7ee9rr5-39VionCpr) evs, Toe presen of rsa orochenscl te bgod of hepre `bppoiotppluiuolnlaatt(ii"oopnnpaabnn"dd))ssuluebvbpeoplposu.pluaTltahiteoionpnsrs,e,sssueunccchheaaossfwwoororgkrakenreirscs,,hflhauaossbrboeceehenaeknk~nncooawwlsnnidndattahitienngbgblboaoacdckktotfootththheeeg1e19n97e70r0'a'ssl,,x"aanndd SNE pemicopial dyof sownworker dite 0adverse ss partsper lion 3/vI's epidemiolog~caI study ofits own worke~ indic~te~ no adverse zff~s at parts per ndllion lleevveellss.. 33MM ddooeessnnoottbbeleifieevveetthhaattaannyyrreea~ssoonnaabblleebbaas.i~sseexxiissttssttoo ccoonncclluuddeetthhaattPPFFOOSS"p"rperseesennttss aa `~suubbssttaannttiiaallrriisskkooffiinnjjmuryyttoohheeaalltthhoorrtthheeeennvviirroonnmmeenntt."" NNeveertvhele ess,ra~ssatapprhreeccaeauuttilioonnaemryys mmeaessausur,ree,, TMsming is oman ohTSCASto $0dock 4s re 3M is submitting this information to the TSCA Section 8(e) docket at riffs time. ? $S8e0e,,8e..o0,..TTaavvese, DDs..R,R.;; CComopmapraiffssoonnooff'"OOrrgag,a'dn""FFiluuaorriiddeeiinn HHuummaannaannddNNoonnhhuummaanr~SSeerruummss,, 5500 aWa. Berar nknCaFsoBors J. Dent. Res. 783 (1971); Guy, W.S., et aL; Biochemistry Involvin~Carbon Fluorine Bend~, mane Chm Soci. 1-58 170 Uh Ah orsSs OrPatHts American Chemical Society, 117-34 (1976); Ubel, F.A.,et al.; Health Status OfPlant Workers ExpoaghthaFaaraorreinidnt oSAPakesd lcRspv,aAtenandeesp.diogesroei.l 04 0ain on Exposed to F/uorochemicals - A PmfminaryReport, 4 Amedaan Indus. Hygiene J. 584 (Aug. ode Ge Doct mos SEH HARTY EA19R74. BESV30 E0L34 1980). 3M has submitted PFOS-relaled medical sucveillance and epldemiologica! information on iittssoowwnnpprroodduucct~ioonnwwoorkrkeerrssaasswweelllaass aanniimmaallttooxxiiccoollooggyy ddaattaaprperevvioiouussllyyttootthheeTTSSCCAASeScetcitioonn88((se)) docket. ,~ee Docket Numbers 8EHQ-'J 180-373; 8EHQ-1180-374; 8EHQ-0381-0394 22660022..00000011 Tvs Tab 355 Exhibit 2602 MNG255508 3M MN02456909 me sicne 1g07 Document I~rocessin8 Cer~er (7407) ne May I4, t998 Page 2 e papmipsms toie o m idpigetae A g HOA , tO e } In the pr~ ofvalidating analytical methodology for measuring PFOS, a product ofthe `essalaemm~pprlloeecsshfferimo~mincianinlddifivlvuiioddruuianalalsst.iwwoinitthphnrnooockkenn~oowwannnooocucctcsuuipdpaeattiliaoobnnosar!laeetxoxprpoyosdsuuerrteeetcttooefdfllPuuoForrOoocSchheae~mmipcipacblashl.e.SvuSeblussbiesneqbqulueoenontdt Te UUannniaitltyeesddeSsSttaoat~feecs~ommmemaeasesurucrireaelddlyPPpIF~oOOoSSlleeldevvseeellrssabbfeertotwwmeeehennum99.papnppbbb-aloanmoddi5b566anppkppbsb.a?>mApnAlaenlsayliysnsedessiofoffefrLleiinmmtiitrteeeddghiihosintssotoroirficctahalle a tion eps O miso bbllooooddssaammpplleessffrroomm19196699aanndd 11997766sshhoowweeddmmeeaan~PPFFOOSSlleevveellss ooff2288 ppppbbaanndd 3333ppppbb,, ee es oe vkms respectively. Analyses of [h~ited animal sera ~amp|es found comparable PFOS levels. 3M also nbe os has conducted qualitative in vitro and in vivo metabolism studies, which suggest the po~oility e Eer ia that non-cccup~onal presem:e ofPFOS could result from the metabolic conversion of other fluorochemicab to P.FOS. Ee et 3M would wekome the opportunity to discuss our finding~ and our plan& We are sending a copy Fre betiogre idr in ofthis letter to Charles Auer, Director ofthe Chemleal Control Div]don, and will be ~onta~fing ay Ty l~n ~ortiy to arrange a meeting for this purpose. In the meantime, please do not hesitate to ei : contact W'dliam Weppnex at (612) 733-6374 with any questions. ~ soe Sincerely, Che, @ Somvermim Group Vice President mii. Chemical Mm4ce~ Group aB pm E tte ip po T 3M also analyzed these sera samples for another fluorochemicet- perfluorooctanoate ('PFOA') ERE [CAS No. 3825-26-I] - but detected the presence of PFOA at quantifiable levels of 12 and 22 ppb in only two of the samples. 22660022..00000022 asTab 355 wneacsso 3M MN02456910