Document MGy0OqYyg4w1zoaKZeOLRzm2a
FILE NAME: Talc (TALC) DATE: 1972 Aug 3
DOC#: TALC150 DOCUMENT DESCRIPTION: Report for FDA - Analysis of Products Containing Talc with Cover Letter
August 3* 1972
Ut Alfred Wsissler, Acting Director-
Division of Colors and Cosmetics Technology
Office of Product Technology
Food and Drug Administration Department of Health, Education and Welfare
Washington, D* C. 2020^
.
Dear Dr. Weissleri
_
- --
Enclosed please f 0f
frSKMSinin^
^
sent me from Washington, --cep* f -1]L1freTJ^.t on separately, as
pharmaceutical
in Hew York and in Boston,
well as a number- uhau I purcnassa j.-*
The analyses show that 59 of the
(by the
detectable amounts of any of th
,+ of -\^% or less could
technique employed, proportions b y V e n t a g e s of
aseaoe detection) , 20 had smajl ^
9 hld small
treaolite, 7 had small percentages oA ^nr/ootii , ?
sub_
percentages of both tremolite an c
^ tiforiQ minerals,
stantiai percentages of one or bouh of -hese aso,,* -
J1 ssnhaailll rreettaaiinn aaunud. preserve t--he original ^eclaens, and the c-ray diffra_crtmo+-g.riTamvs,ouuandtviilseyomue aod^vnie.s.ewimse.
With very best personal regards, Sincerely yours,
^ fy v -' Seymour'' Z. Lewis.
Professor of Chemistry
QE-CPC2-00000011
TABULATION OP X-RAY DIFFRACTION ANALYSES OF COMMERCIAL PRODUCTS CONTAINING T A L O ___________________
A Products haring no detectable amounts of asbestifora mineral; (limit of detactability=ca. 1 to 2% for each mineral)
Product
1 2
3 4
5 6
8
9 10
11 12
13
14
15
16
17 18
19 20
21
22
23 24
25 26
27 28
29
30
Mineral Composition
Talc Chlorite
70%
100^
99% 100%
8950%%
95% &9% 93% 90% 120%
60%
31% 100%
<--
60% 90% 97% 35% 67% 59% k2% 99% 95% 95% 88% 20% 99% 97%
3%
n.d.
n.d* n.d. 2% 2% not
2% 7% 3% 2% n.d.
ru cL 50% n.d* --
30% b% 1% 6.0% 25% 35% 50% 1%
1% n.d* 1% 2% 1%
Phlogouite
7 %
n.d.
1,%
n.d.
35%
_2l-------3% 2% 2;% 2% n.d. n.d. 2% nd.
9%
22%
1% 2%
1% 2% 2% 3% k% 2% zrd* 2% 2%
cK-Quartz Doloaite Other
n.d. n.d. n*d. n.d. n.d.
n.d.
84
n.d.
2% 2% 9%
n.d*
n.d.
10%
n.d.
n.d.
2% n*cL K% 3%
n.d.
3% 3% ' n*d. *
n.d. n.d. n*.cL n*d.
XI d.*
n.d.
n.d. n.d. n.d.
n.d.
n.d. __2$_______
n.d.
n.d.
n.d.
2%
n.d.
n.d. .
7%
n.d. __
6% 2% \
n.d*
n.d.
3% 5% 3%
n*d* n.d.
n.d.
19%
n.d.
2% .
nd.
2n0 ZnUd ZnUd K,S
C'aCO-j X
QE-CPC2-00000012
Prodpot
31 32 33 34 35 3 37 38 39 40 41 42
43 44 . 45 46 47 48 49 50 51 52 53 54
II 57 58 59
ii .
Talo Wff
55% n% 78% 79% y&% 87%
945
66% 81%
'8S6 % n.d* 65% 485 10G% 88% 100^
955 100J
855 905 905 785 86% 19% 96% 90%
Papre
Chlorita
7
4o5
1% 5% 45
3%^ 25% 8% 6%
n.d* rd. 305 405 n.d. 45 n.d.
5%
n.d.
8%
y%,, 155 1% 15%
n.d* n.d.
Mineral Composition
Phlogonlte o4-Quartz
. y%
3%
2%
2%
n.d.
k%
35
2% 2% 5% k% n.d.
1% 45
2
1% n.d,
105
15%
n.d.
2;%
3%
3%
2%
<
n.d.
- 35 n.d,
1%
n.d* n.d, 2% n.d, n.d.
nd*
Dfi
n.d. 2% n.d. n.d,
n.d.
n.d*
45 2%
3% 2% 2%
1%
n.d
3% 2%
n.d.
5% 3%
n,d
' 45
n.d,
3%
Dolonlte
85 8% 3% 8% 5% 7 .1,d.
1%
2% n.d,
5% 5% 3%
n.d. n.d.
k% 7%
n.d.
45 nd* n.d. n.d, n.d.
25
45 n.d* 25
5%
n.d. n.d.
Other
'
' _ ZnO, X
' .
3
QE-CPC2-00000013
S . Trod nets "haring'small;"aao'orrts" ofJfrsinollte- -- more "than 1%% "but not more than {5^)% ^
Product Talc
Chlorite
jfj.ners.1 Composition Phloaiopite ^-Quartz
Dolomite
60
61% 30%
n.d.
61 62
35% 89%
bQ%
2%
2% ,1%
63
8?% 2%
2%..
64
8b% 5%
65
79% 15%
nJr.*d.
66
85%
35
67
75% 15S
i%
68
18% 15*
n.d.
69 70
98% 26%
16*g,%
1% n.d.
71
8b% 10%
n.d.
72
8b% 5%
3%
13
-7992%%
10% n.d.
1% n. d.
74
75
75% DP
2%
76
75% n.d.
77
91% n.d.
5:% b%
7789 8856%% 25%i J%
n.d. 3% 3% bnL%>c/fo n.d. n.d. n.d. n.d. n.d.
St
b% 3% n.d. n.d. 5% 2% b% n.d.
7%
n.d. n.d. 3% b% 2% 5% 5% n.d. 1% n.d, n.d, 5% 5% 15% 10% n.d, 3% 2%
Tremolite
2\% 2%
5;% 5% 3% 2% 5% b% 2%
%2;%
2
23,%%
H3% 3% 5% 3% 5% 3%
o . . ~y
QE-CPC2-00000014
o . Products arlns b n t not more than {5^)/
-- c f C hryattlle
.
Product gale
Chlorite
Mineral Composition
Phloj
af-Quartz
80
k8% ko%
n.d "1
81
__2$_______ 1*
82
76% 12%
2%
83
81% 6%
8^
87% k%
%2% ,
85
83% 5%
86
82% %%
2%
8 4 ______
n.d. n.d. n. d.
4
aore than 1%
T)olotalte Chrysotlle
n.d.
b%
b%
2%
~W b%
38S%
5% 2%
m,
QE-CPC2-00000015
D. Products having small amounts of both Tremolite and Ghrysotile -*more than l%t but not more than {5 *2 )% f each by weight.
Product
Mineral Composition
Talc Chlorite Phlogonite ^-Quartz Dolomite Tremolite Chrysotdle
87
ZQ% 50%
88
6l%
n.d.
89
63% 1%
90
55%
n.d.
91
23^
1#
92
6i
n.d.
93
55#
1%
$k
43*
95
87#
n.d.
nd. n.d.
ncf Jr3
y%
3% 4# 3% n.d*
k%
12%
k-%
5%
25%
4#
8%
10%
5%
7%
25%
5%
69%
3:%
4#
6%
20%
5%
6%
25%
5%
6% _ 35%
4#
5%
\%
2%
n,cpf
5%
5%
5%
.
5%
5%
It
5% 2%
QE-CPC2-00000016
s s ^
P ro d u ow Talo
96
66%
97
31%
98
39%
99
37%
ICO
76%
101
53%
102
65%
'
C hlorlto
n.-i. 1% nd* 3%.
V nd
u n i r a i Composition ,w iA r*i-o
m o 2 B *=3S21. 2 S li
31$%
3:% 3% ht
3%
52 d
6%
7%
5%^
35%
ko%
6;%
nd
2;%
7%
k%
3%
15%
T ra m o n ta C h ry so tiljL S S S 2 = ------------ *----------
OQrtffi
10%
12%
15%
2%
10%
3.%
3* 25% 10%
0* 6% n.,
1%
Pa-AS &
QE-CPC2-00000017
KOBES-TO" JBB T A B O M T E D BATA""'
All products tested were standard and commercial brands,
purchased in drug stores or the drug departments of department
stores or super-markets in the cities of Washington, D. C,, New
York# and Boston,
.
/
-
All data are based upon continuous scan x-ra.y powder diffraction patterns, The precision, in _tera3 of average devia tion, is of the order of magnitude of x2% absolute for each of _ the mineral species reported. The data are given in units of per ' centage composition by weight.
The limits of detectability by the method employed are
of the order of magnitude of 1 to 2% by weight for each of the
mineral species cited,
- --
'
A*
Where an asbestiferm mineral was indicated by the x-ray
-pattern as being present to a definitely detectable extent, its
presence was verified by the use of optical microscopy to dis
close the presence of significant numbers of fiber particles,
B
Where the asbestiform mineral was indicated by-the x-ray
pattern as being present at the just barely detectable level, \
this was verified (or rejected) by employing the step-scan tech- .
niaue over the regions of the questionable diffraction peaks.
The following minerals were estimated by comparing the sum of the integrated intensities at the diffraction angles listed below, with the corresponding summed integrated intensi ties at the same angles of standards composed of the pure mineral
Mineral
Two-Theta Values Suwmad
Dolomite ^-Quarts Gilorite Fhlogopita
31.0 - 31.2 } 44.8-45,0.;
.
20.4- - 20,6} 26,6-27,0;"'-3-9.3-39.7i
6,3-6,5} 12.4-12.8 19*0-19.2.k 25.0-25.4
8.6-9.0 } 25.9-26.1 ; 23,1-28.3t
Only two of the asbestiform minerals were detected in
the products tested. Each of these was estimated by comparison,
with standards made up by Joining the pure mineral .with pure talc
I n various proportions by weight. For both unknowns and standards,
the parameter measured was the ratio of the integrated intensity
of a diffraction peak, relative to that of an internal standard.
His internal standard employed was 5% by weight of % n (OH)Cl,
The integrated intensities were summed at the following diffraction
angles.* ;
o,
Asbestiform Mineral
. Two--Theta. Values Summed
Chrysotile Tremolite
i -
- .
1f
12.0 - 12.4; 24.3-24.8
1 0 . 4 - 10,6 } 27,4-27,6 } 29,4-29,7 }
30.6-30,9 33.2-33.4
.
fd*.? H
QE-CPC2-00000018
Talc was determined by difference.
The following abbreviations are employedi
n.d* *
Z.h 0 -
Zn UJ -
K e
5 =
CaCOi =
X
=
not detectable
sine oxide sine undecylenate Kaolin starch
cal cite phase not identified
unimportant.
because
,
.
aeemed
In several instances, the same brand of product was pur chased in different places at different tines, xo check on the constancy of ccrroosltion of the mineral nireure. Considerable variations,were found. See product numbers 14 and 15; 22, 22 and 2 3 5?"irP&ther instances, constancy within the precision 01 the analytical method fas observed (e.g*, in the case of prod
uct Ho, .?)
Pa^-s 9
QE-CPC2-00000019
Product 19naber
1
. 2.
;
3
'
4
- 28
10
11
12 13
1165
17
18 19 20 21 22 23 2k
25 26
29
31 32
33'
il
35
36
37 $3 39
ko
.......KEY TO PRODUCT NAMES
Product Name
Further Identification
M E N S POWDER, MEDICATED AMOLIN DEODORANT POWDER
'Bristol-Myers {No. IF25)
Norwich
,
AQUAMARINE COOLING SPRAY BATH
POWDER BAGATELLE AMBER DUSTING POWDER
Revlon (l`i-3) Corand (DCS)
BOURJOISBATS POWDER CALDESENE MEDICATED POWDER OARKWKRE BOUQUET BODY PQWPE2--
Pennwalt (527^) Colgate-Palmollv
CHANEL NO. 5 BATH POWDER
COUNTESS ROCEEAU CAKE DUSTING
. POWDER CREPE DE CHINE DUSTING POWDfiR,
MILLOT
-
CREPE DE CHINE POUDRE MIST,
MILLOT
CUT!CURA TALCUM POWDER
DESENEX DESITIN BfffiY POWDER BESITIN BABY POWDER DIAPABBNE BABY POWDER DOROTHY GRAY MSECRET OF THE S&A"
Jergens
House of Fragrance (L1132
House of Fragrance Pures {07170} WTS-Pharmacraft Pfizer {11392) (3/29/72; Pfizer (115A) (5/10/72) Breon (B1Q0O)
DUSTING POWDER
'
EMERAUDS TALCUM POWDER
ENGLISH LEATHER
FABERGE
DUSTING POWniR
FRIENDSHIP GARDEN DUSTING POWDER
FRIENDSHIP GARDEN DUSTING POWDER
FRIENDSHIP GARDEN DUSTlNC- POWDER
Coty (355-^010)
Mem
(2891) Shulton (3/27/72)
Shulton (5/9/72) Shulton (7 /1 3 /7 2 }
HEAVEN SENT AEROSOL BATH POWDER
MIST HEAVEN SENT BATH POWDER
Rubinstein Rubinstein
HELEN PEESSL MLITTLE LADY" .
IMPGRTA, SPAIN MENS* TALC
ISIS FLORAL TALCUMPOWDER JOHNSON3 BABY POWDER JOHNSON AND -JOHNSON MEDICATED
(028Q) (3612)
P0WDER KOSCOT BEAUTY DUST-- OIL OF INK
LANVIN ARPEC-E DUSTING POWDER
LANVIN ARPEGE ROWDERED MIST
LANVIN ASPEC-E TALC
.
LEWIS BA3Y POWDER LOVES FRESH LEMON GLOSSY POWDER
MACY5S SCENTED BOBATED TALCUM
MACY*S TALCUM, APPLE
MAECELLE DUSTING POWDER, HYPO- ,
ALLERGENIC
_
MARY CHESS PERFUMED DUSTING
(1288)
Hanley & James (2K^)
POWDER' ,
'
QE-CPC2-00000020
-Procrg t Huaber
41 42 43
44 45 46
47 48
49
50 51 52 53 54 55 56 57 58 59
Product Name
Purthgj Identlfioatlou
HEHNEN BABY MAGIC POWDER KEHHEN QUINSANA FOOT POWDER
(B112) (H202)
MERCK TALC PRODUCT NO. 6460, LOT
! NO, 6460)
(8039301)
MEXSANA 2387-D MEDICATED POWDER Plough
OLD SPICE BODY TALCUM PERSIAN LILAC DELUXE DUSTING
Shxilton
<
: POWDER
April Showers (LFN)
PERSIAN LILAC SPRAY BATH POWDER April Showers (B200B)
PONDES PERFUMED TALC BODY
DEODORANT DREAM FLOWER
(115B)
PRINCE HATCHABELLI BELOVED SPRAY
- POWDER
QUEST DEODORANT POWDER
,
BEPLIQuE SPRAY BATH POWDER
Parfuns Raphael (004)
RIVIANA FOODS - ITALIAN STEARIN TALC ' For Rice
SEPTEMBER HORN BY POND'S
(19B)
SEVEN WINDS AFTER BATH TALC
DuBarry
(021035)
u s ? talc
7SELINE INTENSIVE CARE BABY POWDER
(I 209)
IVES SAINT LAURENT RIVE GAUCHE SPRAY TALC
Z B T BABY POWDER
(Si021)
ZEASORB SUPER ABSORBENT MEDICATED POWDER
Stiefel
60
AH3USH-DANA DUSTING POWDER
61
APRIL-SHOWERS
62
AVON UNFORGETTABLE PERFUMED TALC
(9884) .
63
BELOVED PERFUSED DUSTING POWDER, PRINCE HATCHABELLI
64
COTY FACE POWDER RACHEL
65
DESERT FLOWER SPRAY BATH POWDER
Shulton (P 1 3X1)
66
EHERAUDE DUSTING POWDER
Coty
67
EMERAUDS SPRAY DUSTING POWDER
Coty
(1 AEY)
68
FA3ERGE FLAMBEAU DEODORANT SPRAY POWDER
(37 WB?)
69
JEAN NATE SPRAY BATH POWDER
(1 N 247)
73
JEEIS TALC, FLESH
.
71
JfiLIE MADAME DUSTING POWDER, BALMAIN
72.
LADY ESTHER FACE POWDER, RACHEL '
'
'
73
liAX FACTOR FACE -POWDER, RACHELLE
'
MEDICATED COMFORT POWDER.
. Parl-ce-Davi 3
75
QE1 de LONDON TALC
'Yardley
(493)
76
TO KNOW ME IS TO LOVE ME - TIMXERBELL
fom Fields, ;,td,
77
TOUCH a n d GLOW PACE POWDER, CREAMY PEACH
Revlon
78
TOUJOOH3 KOI BATH POWDER
Cordsy
-79
YARDLEY APHIL VIOLETS
: .
(4908)
80
CHANTILLY DUSTING POWDER
Houbigant
Si.
CASHMERE BOUQUET________
82
JEAN NATE TALC
i
83
HENNEN SHAVE TALC
(3 81)
84
SHOWER'TO SHOWER BS'DY POWDER
' Johnson & Johnson T550?3G)
35
PUBS BABY POWDER, DABX DRUG
. V
(S.llfi)
86
POND *S DREAM FLOWER PERFUMED TALC
.
(0 13D)
A
T
I
QE-CPC2-00000021
Product Number
87 88 89 90 91 92, 93 94 95
Product Name
TP-n-r-hhe-r Identification
ftT.WAY HYPO-ALLERGENIC FACS POWDER
CONSTANCE CARROLL, BOUQUET TALC
DJEE-KISS TALCUM
FLAMINGO DUSTING POWDER, TUSSY
LANDED LILACS AID HOSES TALC
m m t f TALCUM
MAVIS BODY POWDER
TANGEE
0
ZBT BABY PONDER
Kerkoff (L104?)
Vlvaudou Vlvaudou Luft-Tangee (B0048)
96
BLANCHARD'S DUSTING POLDER
Del Labs
97
BORN WILD DUSTING POWDER
98
LANDER GARDENIA AID SWEET PSA TALC LANDER LILACS AID SOSES DEODORANT BODY TALC
99 KISS DIOR DUSTING POWDER
(Avon (DCC
100
101
TAT WINDS SPRAY TALC
2-14-72,
102
TOSCA DUSTING POWDER
H M
Pa** II
QE-CPC2-00000022
