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3 Specialty Mites Comer H3 p) : GS Ho f AR 226. j030 ror HERES FYI- 0701-1379 - 3N 1 VIA OVERNIGHT DELIVERY ZL June 28,2001 oS DOfofciucmeeonftPoPlrloucteisosniPnrgeCveenntteiron(7a4n0d7T)oxics 4U.0S1. MEnSvtirreoentmSenWtal Protection Agency Washington, D.C. 20460 == 3 a Attention: For Your Information Docket - Docket No, AR-226 Re: SIunlffoornmaatteisonanodn RPeelraftleudorCooocmipaonuends DearSir or Madam: FYI-20-201378 `and rel"aTtheidsccoonmtpionuunedss,3Ma'spavrotolufnotuarryosnugbomiinsgsidoinasloofgudeatwaitohnEpPeArflrueograorodcitnagne sulfonates sMtuuodrioecs,heamsimcaolrse.fuWlley daerescernicbleodsibnegloown.e compact disc (CD) containing a number of ContentsofSubmission `3cMomrpeovuiTnehdwesedeansicnnlofotoseremddaitininofpnorreomvnaitotuihsoensfcuobolmvlieosrwssiinopgnesrc.fhleumSoiprceoacolicfsti:acanlelys,ulifnonparteepsarainndgctehrstasinubrmeilsasteidon, > > PPeerrfflluuoorrooooccttaannee ssuullffoonnyaltefsluoride > > PPeerrfflluuoorrooooccttaannee ssuullffoonnaymliadmei.do (ethyl) acetate > > NPeeertfhlyulorpoehrefxlaunoersouolcfaonneastuelfonamide > > NNeemeetthhyypleprefrlfulourooroocotcatnaenseusluflofnoanmaimdiodeotehtahnaonlol > Perfluorooctanoic acid soirncesoomureoDfectehemsbeemratseurbimailsss,iohno.wever, no additional information has become available JURE 85010000015 \ -- ee-- Contain NO CBI : ePaaesz, 2000 tohlidsersusbtmIundiisteshsiiwsoensuhcboampviiesessioroefnce,tnwwtloeysatlruoedciaeetnsec,dlsoiusnbiomnuigrtpifreiildemsa.MrailWyyen15he,aw2ve0in0af0losraomnaditniJcoalnnu,udeaadrlyoonn1g8t,whi2et0Ch011a foefw respectively, neitherof which was previously included on a CD. On the enclosed CD, you will find: A copyof thiscover letter. * cAonpiinedsoefx tthootsheesttouxdiiceosl.ogy, epidemiology and medical surveillance studies, and * lAifenustmubdeiresoffotrhewhiitcehmsweonhtahvies ipnrdeevixaourselaynasluybtmiicatlerdeproeprotrstts.o aWcecohmapvaeny insitnudidcyatreepdoortnatphpeeianrdeedx. where in our prior submissions the companion in-life * Anindepxhyasnidcaclo/pciheesomifcaelnvpriorpoenrmteincst,al studies, including studies of enveciortooxnimcietnyt,aalndfate, rTohbeussettnusdvuimiemrsoaorfnimepesh.nytsiaclalmcohneimtiorcianlg.properties, fate and ecotoxicity are accompanied by wInhiacddhiytioounmtao ythaecicnedsesxtohfe eennvviirroonnmmeennttaall asttuedisetsudbiyeschfeormimcuallt,iptlheercehaermeicianldiscbesy ftrypoem opofisnttusdy1:0 ahnydEroxleycsuitsi,vephSotuomlymsairs,yodresbciroidebgirnagdathteiosne.rieEsaocfhostfutdhieessoefstuhbejevcatriinoduisces fluorochemicals. * wuAwpnedahutapevdseattnehoettboitinhbclelibuodgreiadpihbnicthlriesfibeoirbefolnpicuoegbgslrwiarspehheyhadaavlbp iestteprrhraaecttvuysiroeoufsiltnyh3epMnr'ousvmipedoersdos.uesssPiploreneas.seenTtnahotitiseontshatto CthheemSiosctireyt.yofToxicology or the SocietyofEnvironmental Toxicology and nwoiwthian stAihgsenisifeniccotauinortnpsnausfmtorbsecuarbcomhifscsshiteoumndiisce,aslwt,ehabhtyaaevdneddroperosgisannmtiuozlretidtpytlpheeefoslftuuosdrtiouecdshye.bmyiHccoahlwesem,viecarWl,e,tahhneardveeare rplaritsithoeerdrptrthahceatsniecies.ntduedTxiheiusnsgt,otgfheoertmheexmrauumlntpdilpeelr,eamtesidemicectsiaolunnsodufersrvtetuihldeliaevnsacreaiododufrsepcslhsaenitmngiwcomarullksteiarpsslheeaxcsphboeesmeeincdaol1u0sr, smsuuerlrvtueimip,llleaarncecheleimisintcdeadelxos,n,alnoyrdotnahcreeeannaotatltyhtieincdbaeelxgeiddantnuainnodgneorfftlPhuFoeOrSot,cohxPeimFcioOclAaol,gyl,eeteve.eplisSdiiemnmiilgoaerlnleoyrg,ayltahpneodpumleadtiicoanl 2 : JPuangee 28,2000 caethnevtmihiercoeanlnmsdeo.nfttalhebieonmvoinriotnomreinntgalstiundideesx waintdh amrueltnioptlseetpaarrgaettelaynailtyetmeiszaerdeulnidsteerdsipnecaisfeicction tinheMTaSyCaWAnedSheJacvtieuooinfnnSc2cl0ued0do0ecdkdieintdtshniionstcseiunobculmruidslesasictoosnpuibcemosiopsifseaisloonlf.tmhaeOteuvrrairalialorsugsewmedaothcearuvimeaeltnsrtasnessnumtbitmtoitsetsdhietoons sThuaSbvCmeiAsinsScielocuntdsieodonftt8heendrpeorccoekvneittdTeovSperCreAltihSmeeicnyeatariryosn.d8atHaoswbueebfvmoeirrses,ifaionsnasla rocenopnotvrhetenssieaerCneDcasev,atoialtahtbehleersefeaodrers, we submission. Additional Data to Be Provided in Future Submissions asrteudnioets yIfeontrmwayvhaiilcletahtbelrree:ptoorDtrs.wOosucladrHbeerfnoarnthdceozmidnagt.edYMoauywi2l3l, n2o0t0i1c,e Ithnaot tseevadernalumkbeeyritoefms + rPeovriteiwo,nsoanfdtthheusPFthOeSre1p0or4t-hwaesknocthreonticbebeinoacsosmapylearteedundergoing further pathology BreecpoarutsoenatthteenNt-ieotnhhyalsFbOeeSnEf1o0cu4s-ewdeeokncthhreofnuircthbeiroarsesvaiyewhoafs ntohte yPeFtObSeesntufdiyn,altihzee.d. * The reports on the 6-month primate studies of PFOS and PFOA are not yet complete. * tAhnealryetliecvaalntreipno-rltfsetsotuadcicesomapsatnhyeyalbletchoesmeesatvuadiileasblwei.ll be submitted concurrently with available`.We will continue to provide information on a regular basis as it becomes CSDubmission form onlUyn,liwkiethoouurtpapsaptesrucbompiiscssi.onWs,ewuendaerresstuabnmditthtaitngEtPhAeavnodluOmEinCoDusrmeaptreersieanltsatiinveCsD bheavmeodfiofuinedd.thi3sMfowrimlaltmmaoisnttacionnavepnaipeenrt.coTphyeaCndDtihsefoorrigrienaadl-oCnDlycpouprypoofsetsheanddoc1sumneotnttso tAhse ienvdeinctaotfedaninytdhiesncorteepapnrceyf.acing the CD, the paper copies will control over the CD in navigatiTohn.e enclosed CD provides several "roadmap" pages at the beginning to facilitate 3 --_-- : , - Pnaege2s8,2600 contact Wmee wliotohk afnoyrwqauredsttioonosu.r continuing dialogue with the agenes. Pleas fee fee to ce: DDrr.. OCshacralreHseAmuaenrdez Very truly yours, Unidnt 4pm Michael A. Santoro DSiarfeecttyoarnodfREengvuilraotnomreyntAaflf,aiHrsealth Specialty Materials Markets 3M Building 236-1B-10 3M Center St. Paul, MN 55144. 651-733-6374 (phone) 651-733-1958 (fax) E-mail: masantoro@mmm.com HB ere eo