Document MGYvJzReZwEe9xg5rQa5pgXxa

FOR'DU FONT USE ONLY AR226-2886 Copies to E. I. du Font de Nemours and Company Haskell Laboratory for Toxicology and Industrial Medicine Elkton Road, Newark, Delaware 19711 HASKELL LABORATORY REPORT NO. 562-80 MR NOJ 'Material Tested<--& Haskell No._ Other Coces" Study Initiated/Completed 7/15/80 - 7/17/80 Jackson Lab SKIN IRRITATION TEST ON RABBITS Procedure: Six male albino rabbits were clipped free of hair on the trunk and lateral area and placed in PDA-type stocks. Doses of 0.5 g undiluted test material were applied to intact skin under 1 1/2" x 1 1/2" 12-ply gauze s res. Rubber sheeting was then loosely wrapped around the trunk and secured w adhesive tape. After 24 hours, the rabbits were removed from the stocks, che patches taken off and the reactions observed. Observations "ere also made at 48 hours. Results: 24-Hour Observation 48-Hour Observation Erythema Slight 6/6 Edema None 6/6 Erythema None 6/6 Edema None 6/6 ^ W Sanded. Does not contain TSCA CBS l - SuiMfery jBRBcauaed slight skin irritation in 24 hours and no irritation in 48 hours when tested on the shaved intact skin of rabbits. ^ Even though this compound caused only slight to no irritation, good industrial hygiene practice would be to wash thoroughly with soap and water in the event of skin contact. ^ 4 ^ , Report by: L//6B6iol lcyheAmaisth l e y(y^ Approved by; .P/a^.JLJ y \C^~.- Gerald I.. KsnnsQy Chief, Acute Investigations Section PA:jrg Study Director: 0. L. Dashiell 1980 Report Ho, 562-80 - 2 - igompany Sanitized. Doss not contain TSCA Cg