Document MDpy0xBDoqynKaRqyM9q7ark

Monsanto s mat* iMfM**locatiom)J P- Mleure - Technology Department - South Second Street DATS U A JB C T TO , October 20* 1970 , IMPURITIES IN AROCLOR i . R. E, Keller 'Research 1 ; .. ce-W . B, Papageorge - GO W. R. Richard - GO M. W. Farrar - Re s . 1 H. S . Bergen - GO E. P..Wheeler - GO M. W. Dietrich - Rea. E. M. Emery - Res. 2 E. S, Tucker - Res. .2 R. H. Munch - Res, 2 Researchers at the University of Utrechtr The Netherlands, have reported finding low levels of polychlorinated dlbenzofurans In competitive polychlorinated biphenyls. They .also analyzed Aroclor 1260, lot AK-3, and did not detect any oxygenated impurities. -Because of the reported high toxicity of polychlor inated dlbenzofurans, a study was undertaken to determine If these, or reflated, compounds ex,lst as. Impurities In our products*. This memo'contains the preliminary results of this study. Low levels (about 25 ppm) of polychlorinated dlbenzofurans were confirmed In Fhenoclor D.P. 6, a competitor to Aroclor 1260 from Prodelec (France). Aroclor 5442 appears to contain about 2 ppm polychlorinated dlbenzofurans; none were detected in any other Aroclor studied.* However, each of the Aroclor 1200 series contains polychlorinated naphthalenes at varying levels. The Aroclor 5442 contains polychlorinated anthracene or phenanthrene Results are summarized In the accompanying table. The Aroclor 1242, 1254, and 1260 samples are the same lots tested for toxicity by Industrial Bio-Test Laboratories. Th method used to determine these Impurities Is similar to that of J* 6, Vos, et al, Journal of Food and Cosmetics Toxicology, In press. The sample was eluted with hexane through a Florlsil column. The Impurities remained adsorbed on the column and were eluted later with diethyl ether. Qualitative identification was by GC/MS. Quantitation was by electron capture GC and mass spectrometry responses. The concentrations reported are not precise. ' The quantitative and reproducibility aspects of the* separation step could not be thoroughly Investigated in a brief study. In addition, due to lack of suitable s t a n d a r d s n o response factors could be deter mined for the electron capture GC measurements. All concentra tions were calculated assuming their EC/GC response was Identical to that of 2, 3, 7, 8-tetrachlorodibenzo-p-dloxin. For these reasons concentration ranges, rather than.precise values, are reported. J. ? Mieure db NEV 036881 IH .IO N BV, II*