Document MB64v73MYKekYq7Evy10mNok
R&S 103500
Liver Angiosarcoma Cases
, Circulation
Dr K S Williamson Dr C Paddle Dr D P Duffield Dr W G F Adams - (5 copies - ICIA, AFX I, Duperial) Mr G J Sleddon/Mr J B H Sheaff Dr D W Plester Mr L F llill. Mi 11 bank Mr Brian Hasler, Vinatex Hr H II Williams, BP Mr R II Hards, B1P Dr J T Carter, BP Mr T L Phillips, BP Dr P Lewis, CIA Dr J R Tassignon, Solvay Mr J C Thomas, Rhone-Poulenc Dr Renzo Mattiussi, Montedison Mr M Bonnefoy, Solvay Dr B List, Lonza Mr P G Claus, AFT1E Dr J G Kammuller, Shell Dr L de Boer, Shell Mr S Wejdltng, Kemanord Mr C Rangnes, Ilorsk Hydro Dr Terwlesch, CWII Mr H Emmlnger, VKF, Mr P de Voogd, Shell Dr E Lloyd-Jones, BP Mr Owen Jones, llillhouse Dr Brian Bennett, Hillhouse Dr Peter Wright, PCD Wilton Dr F W Best, Everberg Dr G Horcross, Everberg Mr C D'Haenens, APME Dr C Bishop, EMAS Mr B Werner, EMAS Dr Spirtas - NIOSH, Cfncinatti Ms R Kaminski - H10SH, Cincinatti
Dr
K:
Dr T R Torkelson, Dow Mr J Lawrence, SPl Mr J T Seawell, CMA Washington Mr R N Wheeler, UCC Dr A Ross Adams, Air Products Dr Mayo Smith, Air Products Dr John Barr, Air Products Dr Walter D Harris, Unlroyal Inc Dr Robert K Hlnderer, BF Goodrich (Cleveland) Dr R A Krueger, BF Goodrich Dr M N Johnson, BF Coodrich Dr J Possberg, Wacker Dr J Rety, RP, St Fons Dr P Lazard, RP, St Auhan Dr I A Friedel, Berufsgenosscnschaft der chemlschen
Industrie, Heidelberg
Prof Dr Thless, BASF Dr D M Ferguson, 1C1 Americas Mr D Ryerson, 1CI Americas Mr A J Wheeler, IC1 Americas Mr M J S Gibbons 1CI Americas Dr Gary Ter llaar. Ethyl Corporation Prof. C Maltonl, Bologna Dr J William Lloyd, Osha Dr David Bryson, AC Division Mr S Nakamura, Japanese PVC Association Dr Peter Baxter, CDC Atlanta
JS/MJT/D-58 1 Hay 1980
R&S 103
;sv'
-
Table Sequence
Belgium
Canada
Czechoslovakia
France
Germany
Italy
Japan
Norway
Sweden
UK
USA
Yugoslavia
Incidence of Cases pa (Table 1)
Distribution of Cases
by Country
(Table 2)
Pattern of Cases by
Factory
(Table 3)
Latency Periods (Table 4)
Annual Geographical Incidence (Table 5)
t
IMPERIAL CHEMICAL INDUSTRIES LIMITED PLASTICS DIVISION
LIVER ANGIOSARCOMA CASES (REVIEW DATA - 1 HAY 1980)
Acknowledgements Significant: Changes & Comments
I Page 1! - German Case 13 - In the 8 January listing I did not notice a typographical error. This man was born 1904 and
2-3 not 1914. This error is corrected in the present issue.
4 5-7
8-11 12
13 14 15 16-17 18-22 23 24
25
26
27 28
2 At the OS11A/NIOSH/NIE11S Symposium atflethesda on 20/21 March 1980 Dr H WEBER of Der Staatliche Gewerbearzt stated that there were now 17 confirmed ASL cases in W Germany. I presume cases 13 and 14 are now histologically confirmed. Perhaps Dr Friedel or Mr Emminger would care to comment and also give me the data I don't yet have on case 14.
3 In the 8 January issue, I commented that, after a long interval without any cases, the UK had had two new cases bringing the total to 4. This total unfortunately became five on 9 January! It is curiouB that the five UK cases Bhould have occurred 1 In 1972, 1 in 1974, 2 late in 1979 and 1 early 1980.
4 As a continuation of the above point 3, no one has commented to me on Table 5 and the geographical split of ASL deaths. I would repeat my questions. Have North American ASL deaths tapered off? Or Is thiB just a temporary lull? Are West European ASL death rates increasing? North America started to have ASL deaths a decade before W Europe. Has North America peaked out and (hopefully) finished before W Europe.
5 We still do not have any answers to the bizarre clustering of cases in certain factories. Even the distribution of "clusters" is peculiar. Table 3 confronts us with the question why so few plants In H America have been affected while the ASL cases are more evenly and broadly distributed over W Europe plants.
J STAFFORD Division Manager Health and Environment Protection ICI Plastics Division Bessemer Road Welwyn Carden City Hertfordshire England
R&S 103502
>!f fja. 1 Km-;
m
i
IHrMlAt, CHEMICAL IHIHISTRlER LIMITED plastic* Division
Unit hi|lor(Mi Caeee - (Review Dtttt 1 Nqi i960)
l.......... 1 1 i 4 5 T s
) 10 It 11 13 14
13
couhtrt gm REFERENCE BO
HAMS 01 INITIALS
DATS or BIRTH
COHPART
FACTORY
FIRST TC nrosoRB
MTS or DIAGNOSIS
ACS AT oiACBoaia
TRARS OP
exposure to
0IACB0S1S
TRARS OP EX POSHES
DATE OF MATH
HISTOLOGICAL COHFIRHATIOH
ESTIMATED RlrOSORS
LETEL
0CCUPAT10H
OTHER CAREER HIGHLIGHTS
Page t
IS OTHER COHMEHTR
BELGIUM 01
11.01.13 toln;
Jeoeppa OO.OT.3S 00.03.T
3
to
IT 13.0i.TA
Tea
1llfl.1i Antoclaanar Driller In a Hepatic taata
14 pre
foundrp
In Oct I3T4
1330-tits
(1 Tra)
ware noraial.
aapoaad to Pol?worker Fa roar
Retired
100 p]a 3 pro
(13 pra)
Feb 13TS
for S hr*
Hart In glaaa llnapl tal lead
par dap
tnd. 4 chenl- Hap 13T4
and cnl Induetrp
certalnlp
Cooplate
tinder
Clinical and
300 ppo
career detalta
ln,i to
are (Iran In a
So paper bp
autoclave*
HnMet at al
TWi-HH
In Arch. Help.
aapoaad to
Had. Hoc.,
30-100 ppo
HpR. Hed.
0 bra par
Trar. Had.
dap.ln
LaB.
15 I3TT pegaa
autoclavae
601-ill
aapoaad to 30-100 ppa In autodata rooa TlfRM""
PR" 13T5- 30
PP RETIRED
1 Tab ISPS
R&S
503
r
1WMMI CHEMICAL INDUSTRIES HMITEt) mastics ditision
LITER haloittcm Caaea - (Revie* DiUI 1 Ikj 1JW)
* All dalci na OR ajalea
Canaria
DAT - NORTE - TEAR
Sheet I
'* Data publifHe(4 in Journal of
Oce Had I37B Ml<> 318-3*0
*** Haaf of datea altered to fit N10SH 31 /3/77 Hat
Fage 1
1 1 3 4 34 1 0
* 10 11 11 13 14
is
COUMTET AM) REFERENCE HO
DANE 00 INITIALS
HATE OF BIRTH
COHPAlfl
rACTORT
FIRST K EIFOSORS
DATE OF DIAGNOSIS
AGE AT DIAGNOSIS
TEARS OF EirOSORE TO
O1AGN0S1B
TEARS OF EirOSORE
DATE Or DEATH
HISTOLOGICAL COWriRHATIOR
ESTtHATRD EirOSORE
tETEL
OCCUPATION
OTHER CAREER tttCHLtCNTS
14
OTHER comem
CANADA 01
BltANlI ICAR
I3.tl.t3
1ft*
its*
41
10
II 01.04.33
Taa
Reactor cleaner
Operator
Saofcer
polpaerlaatlon
01 04.03.14
U41
1*31
43
14
14 11.11.31
Taa
Maintenance, Operator lllurlght, pipefitter
Worked overtlee Ranker
03 14.00.It
1**1
mi
41
11
10 13.01.41
Taa
Operator, foreaen
Worked evertlee ffon-aeoker
04 01.04.lf
Ifts
1*41
40
11
11 11.01.40
Tee
Reactor cleanar
Operator, foreaen, eater coolleg onlt
Uorked overtlei Ranker
0) or.os.it
1*4*
1*40
31
14
03 03.01.40
Taa
Reactor cleaner
Hater cooling Worked
unit
overtine
Booker
04 13.11.If
if*r
1911
31
14
11 10.04.11
Taa
Reactor cleaner
Maintenance, lllrl|1it
Worked overttmm Blanker
Of Of .tl.tf
1*44
1*11
31
14
13 14.11.11
lea
Reactor cleaner
HacMne chop nperatnr end poll unit
Mtorked overtIne Hooker
00 11.03.10
1*41
1*13
31
11
Of 11.04.11
Taa
Reactor cleaner
Hr Intenance
In plant
eacMoa elmp IS jral Svofctr
Of lf.Ol.il
1*44
1*14
31
10
14 04.09.14
Taa
Furnace p. pipefitter |Maintenance
i
Worked overt 1at
Ranker
R&S 103504
.
"4,
-IV.-
PLASTICS DIVISION IMPERIAL CHEMICAL INDUSTRIES UNITED
LIVER Riibureiwt Cm* - {Rerlev Date! 1 Hrjp I960)
DAT - HONTH - TEAR
Slice! I
* All date* iim UK ijatn
CenaJe
'* Date puhl I it>H In journal of
Oee Had 1)7# pagee 339-MO
* Hanp of da too altered to fit HIOSH 31/1/IT Hot
Page 1
I 1 3 4 16 ; S
) 10 11 12 11 14
is
16
COIfflTET AHO REVERENCE NO
DANE OR INITIALS
DATE OF IRTN
COMPART
FACTOR!
FIRST VC ERFOSORE
DATS OF DIAGNOSIS
AGE AT DIACNOSIB
TEARS OF EXPOSURE TO
DIAGNOSIS
TEARS OF EXPOSURE
MH or DEATH
UISTOLOGICAL OONFIRHATION
ESTIMATED EXPOSURE
LEVEL
OCCUPATION
OTHER CAREER HIGHLIGHTS
OTHER COMMENTS
CANADA 10
16.01.13
1)13
1)74
61
23
14 00.04.71
Tea
Reactor cleaner
Furnace op.
etntenance, packaging
Ex-evoker
-
-
S 103505
a;
INFER1AL CHEMICAL INDUSTRIES LIMITED ELASTICS HITISION
LITER Angloaaremaa Casas - (Ravtaw Data) 1 May I960)
1
1 1 4 )0
1'
a
* 10 II 11 I) 10
1)
COUHTRT ART* REFERENCE NO
HAKE OR IHITtALS
DATE Of SIRTtt
C0HPAN1
FACTORY
FIRST R EEFOSHRE
DATE OF DIAOMOSIR
ACE AT DIAGNOSIS
TEARS OF EXroSIIRB TO
DIAGNOSIS
TEARS OF BSroSURB
DATE OF DEATH
HISTOLOGICAL CONFIRMATION
ESTIMATED E1FOS1IRE
LETEL
OCCOrATION
OTHER CAREER HIGHLIGHTS
CZBCHOSLOtAeiA
01
00.00.10 tata Co Mmkgr 00.00.SI 00.00.1)
00
IS
IS 00.00.10
Taa
01
00.00.10 tala Co Hanky oo.oo.si 00.00.00
*0
1)
1) 00.00.00
Taa
10
OTHER COttKNTS
1!
1 1
t
_________
R&S 103506
IMPERIAL CHEMICAL INDUSTRIES LIMITED PLASTICS DITlStOH
LITER hi|litcMi Caaaa - (Aaataa Ditei 1 Hay 1990)
fr rnce Sheet I
Faga ]
1 1 3 4 16 7 0
T to u 11 13 14
IS
16
COUNTRT AMD REFERENCE HO
NAME OR INITIALS
DATE OF RIRTN
COHPANT
FACTORT
FIRST VC
exposure
DATS OF DIAGNOSIS
AGE AT DIAGNOSIS
TEARS OF EXPOSURE TO
DIAGNOSIS
TEARS OF EXPOSURE
DATE OF DEATH
HISTOLOGICAL CONFIRMATION
ESTIMATED emraime
IEVEL
OCCUPATION
OTHER CAREER niGNLIGItTS
OTHER COHHEHTS
FRANCE
01 H
11.04.14 *r
Aoaae-
00.01.46 10.01.61
43
11
IT IT.01.61
Taa
Nish Autoclave
UlM
worker ml
cleaner
If T"
Ref. Rarler et el Arch. Hat. Prof. 1 30 n* 3 Nor IS p Ill-Ill
01 SIM
01.06.11 FCUE
Hrtgnoud 06.01.IT 11.01.11
61
16
11 14.01.11
Tea
Nish 2 jrre (mi
Italian
Her.
(NI0S1I no
noiKMier
origin
G gonnatnn et
coanent)
10 yra an pol pier-
el 'Hamel le preeee
leatlon
eedleel e'
S Ho* 1T11
P T
1
0) HAT
06.01.10 up
St Pone 00.00.46 11.01.11
11
IT
IT IT.06.13
Taa
nigh Polrmrlar VCH production Ref. Retjr et
10 jti aa autoelare
16 pre Italian Pint
et Arch. Hal. Praf. 1 SI n*
cleaner
Sliephe rJ(
6 Jana IT
Compounding Sawyer, Haeon p SSI-SS5
3 pre
04 HOR
11.01.11 FCUE
Bri|Mu4 IV.10.4V 16.01.16
4V
16
16 04.01.16
Taa
High Hottoaer
production
worker
1 yn
1 PVC
1 filtration
1> pre
I
----------------------1-------------------
(
0) ^
1T.0I.3S j PCVK
RtIrimuA 10.01.61 13.01.16
IS
II
II ill.0S.T6
Taa
High PolfHorlter
11 pre
1
1
l1 !
j
!
iI 1
1 1 i1
Ref. P Cornier*
et el "Healne
dea hoopltanw j 10 Septenbre I
lfT6
1
Prevtonalp fied|
Hone
I
angloaereooa*' !
thrill ML CHEMICAL ItttlOSTRIRS LIHITIO elastics omstoit
LITRR AagloaareOM Caaee (Rivtew Datel 1 hny I960)
France Sheet 1
h|( ft
1 13
COUNTftT AHtt RftHRIHCI HO
HAM Oft IHIT1ALR
hath or R1RTH
4 GCttfAHT '
3 rAcroRT
ft
riftsr vc uroseftft
1
MIR or OlACHOSIS
0
ACR AT OlACHOSIS
9
TBARS Or RtroSURR TO
OlAGHOStS
10
1RARS or nrosws
-- II 11 13
---------------------- r
13
DATS or MATH
HISTOLOGICAL CONFIRMATION
RST1HATED RKFOSURR
LEVEL .
1 OCCOrATlOH |
OTHRR carf.fr
tllGHLIGHTS
It
OTHER COmFHTS
RRAHCR Oft
r*
14.04.34 rone
01.01.38 11.OB.1ft
41
IB
' 13 ii.09.rc
Taa
Moderate (I93B-1940)
(H10SH
1 jrra
filtration
11.09.1ft)
10-11 ft*
polpuorker
and works
laht
Tlila aan had AOL prlar ta AS. Ann. da Knl. Frol. Iiitp *11 p t43 4 ft. AOL vai found In 1911 flaa pro ha fore ASL
or Gift
it.o4.ir nr
St Auhan 01.01.30 Altar
49
1ft
11 01.01.lt
Tea
HlRh
Plant fore- 1*71-* attain Olad of
death
(NlftStl no
an In
aeetlon In
eptlceeala
HtOSH
polymer-
It Aohan
Saatl Hear
aajra
taction
laalnn found
00.01.1ft
after eutopap
OR R
01.04.34 Solrap
Tavern
13.03.31 03.11.13
41
19
19 30.01.11
las
Moderate d yr* packer
1 autoclave
clnr
14 yre
ant octave
worker
tlad Keen
tunnel worker prevtowalp
09 n
Oft.IO.l4 r
St Sana 10.01.4ft lft.04.lt
1
IB
IS lt.11.1!
Tea
Hl(h
Polyner-
10 pra la
Operated 4a 71
1eatIon
aalphorlc
for renovel of
operator,
acid fectorp, tweonr fro*
autocleaner, storekeeper 4 liver and
autoclave general
died after
leecond
i faurgleal
[operation for
jblllo
[bronchial Irietiile
i
1 1i
R&S 103508
IMPERIAL CHEMICAL INDUSTRIES LIMITED
fustics mr is ion
lint Angioiercosa Cases - (Reeleu Dstei J
W)
Trance Sheet 3
m
Page 7
F
1' 1 i 4 3S 1 B
9 10 II 11 13 14
13
COUNTRY AND REFERENCE NO
HAHN ON INITIALS
RATS Of iirni
CONFANT
FACTOR!
FIRST VC El POSHER
DAT* OF DIAGNOSIS
AGR AT DIAGNOSIS
TEARS OF FIFOSVRE TO
DIAGNOSIS
TEARS OF BEFOSURR
DATE OF DEATH
HISTOLOGICAL CONFIRMATION
ESTIMATED EXPOSURE
LEVEL
OCCUPATION
OTHER CAREER MTttlMCttTS
" t6
OTHER COMMENT!!
Franca
10 vf
14.US.19 RF
St Toes 00.11.34 00.01.IS
36
11
11 00.01.76
Tee
High Autoclave 10 yra tn
Hied of
cleaner
mechanical
pulmonary
engineering emholfam 9
Industry
deya after
1946-1996
surgery
11 L
13.01.11 RF
St Foal 00.01.41 11.01.70
64
17
31 11.11.76
Tea
Nigh
1941-1946
a Central Consent
polymer-
At AphR mtg of 9 June
leetton
1978 Hr JC Thome#
general
reported that 6 out of
purpeae
the 10 french ceeee Ned
worker iiii-lifi
keen Involved In plant terl-op and 9 nut of
VCH 10 had keen In combined
egntheele
TQt and fVC piante where
(IICI 6
VCtl made from acetylene*
Acetplene)
(In hie tetter of
Foresee
1 February 1979
(agent
Hr J C THonaa confirm#
4a ealtriae)
that Caaee 2t 3, 4, 6
and It had worked In
retires
monomer aa welt ee
polymer)
11 13
!
1C.0S.I4 rcur
Irtgnoud 09.01.49 00.03.79
63
30
17 11.06.79
Tea
High Monomer
prodactIon
end folyaer-
laatlon
operator
19.01.11 golvay
Tsesas
13.09.61 16.06.79
1
40 16 11 11.06.79 i
1
1
________
Autocleaner 2 pro, Autooparetor 9 gre, Coftolpwii 4 yra
1 gre ee egete Cigarette
echanlc.
amoker until
10 gra aa
1974. Ill all)
enaseller In of 1977 See to
aanltarg ware Oeaophegal
j
anulaeture rartcea.
Surgical
Intereantlm I
13.03.79
|
(right
I
he pa tactMg) 1
R&S 103509
i
IHPERIAL CHEMICAL INDOSTHtSS UNITED ELASTICS OlViSIOM
LIVES ta|luHciMi Cam - (Real.. Datal 1 hj 19W)
Cenaanf Sheet I
Pase S
t 1 1 4 JS T B
V to 11 11 tl 14
IS
COUNTRY AHII REFEIEHCR RO
RAKE OR INITIALS
OATS or BIRTH
COMPACT
EACTORT
rtSBT VC EXPOSURE
OATS or BIAGOOSIS
AGE AT OlAGimSIS
TEARS Of EXPOSURE TO
OlAGHOSIS
TEARS Of
exposure
BATS or DEATH
ninmnctcAL COHCTRHATtOH
ESTIHATEK EXPOSURE
LEVEL
occurATION
OTHER CAREER menu aits
10
OTHER COHHEHTS
GERMWn 01
00.00.30 Dynaalt Trnlederf 01.10.30 IV.OV.OS
SB
11
ii IS.01.4V Taa (H10SN)
Polyworhar
01
00.00.11 Dynastt Troladort 14.10.ST 1S.0V.T0
IV
11
n 14.11.71 Taa (KIOSK)
Pelyworker
01
00.00.10 Dynaalt
Rhetnfel- 0V.0C.S1 00.01.71
41
11
10 10.10.71 Taa (KIOSK)
rilling
Reported under
Ben
ye*tic Me
non yolyaer-
eroaol c*a*
Motion
with PC
worker* In
NIOSH list of
31.1.77.
Thl* of course
Je etrlctly
correcta
However 1
wonder
whether thl*
aan bad high
espoaur* to
VCM In hi*
can filling
operatlont
04
00.00.10 Vaclar
Rurj-
10.04.ST 10.11.T4
44
IT
IT 1S.II.74 Taa (KIOSK - 200-300 pi* Polyworker 1 1951 van
Clinical
Haatan
no content) Oat M|ll teayorary cutocteener details In
daring t |t autoeleaner for 1 yr
paper Of
antoelean#r
Colei at at
Vlrchowa Arch
A rath IV70
171 p 1VS-101
1
R&S 103510
$
ihprrial chemical industries lihiteo
plastics Dmmm
LIVER Angloeereoae Caeee - (Review Ratal 1 Kay W)
Geraenp Ehaat 1
Page V
~n
nrn
1
345
7
0
5 10 (1 11 n 14
15
16
country Aim REFERENCE m
HAHE OR INITIALS
DATE OP BIRTH
CONTENT
VACTORT
FIRST VC BtFOSORE
BATS OF DIAGNOSIS
ACS AT DIAGNOSIS
TEARS OF BirOSORR TO
01ACN03IS
TEARS OF RRrOSVRR
BATE OF DEATH
tllSTOUICICAL CONFIRMATION
ESTIMATED EXPOSURE
LEVEL
OCCUPATION
OTHER CAREER mciiLicnrs
OTHKH COtHEHTS
CERHAH1 05
00.00.56 Roachat FrankFort 01.04.60 10.11.75
11
05 16.11.74 Taa (NIOSK)
K Cheats ays "claalitry taboratorIan tn thi TechnoLogleal Research
OcparNent" (HIOSN tayi aaalatant factory chealat which aajr ha wrong translation)
Confirmed
Reported Mr non-polfacrlaatlon workers In Riosn Hat of 31.3.72 and 1.70. 1 don't think this la a correct classifies*Ion by HIOSRe The an nay have keen Involved In fCK polymerisation In pilot plant or In wain
Ofi (NIOSO |ltaa aa Caaa 05)
07
00.00.31 tones
VatRabat 16.11.61 00.00.75
41
00.00.16 Hecber
Nr|-hldHI
15.04.54 ll.tt.75
45
11
11 10.01.75
Tea
It
11 11.11.75
Tea
(Riosn
7 11)
PTC - Ha nulactuca Shift Leader
PTC Hans-- lecture and all work fact eutocleaning 12 yre
forenan Tech Dev S fri (1967-1973)
OR
00.00.17 D7na.lt Trotsdorf 15.07.54 06.04.75
50
11
11 15.11.15
Isa
7 Foljrwsrker 1 I
i
! 1
M
103511
fM
INTERIM. CHEMICAL INDUSTRIES LIMITED rumci division
LIVER Angloearcoaa bin - (Review Date) 1 Kay IJWOj
brimj Sheet 1
Tag* 10
1 1 1 A 1 T 0
f 10 11 11 11 IA
IS
COUHTRT AND RETERENCS
MO
NAHR OR INITIALS
DATE OV BIRTH
COMMIT , TACTORT
riRST VC BirOSORE
DATE Of DIAGNOSIS
ACE AT DIAGNOSIS
TEARS OT BirOSORE TO
DIAGNOSIS
TEARS OT EXTOSURE
DATE Of DEATH
HISTOLOGICAL CONFIRMATION
ESTIMATED SRPOSURR
LEVEL
OCCUPATION
OTHER CAREER
RICIIMCRTS
16
OTHER COWHEHTS
CERHANT Ot
10 (NIOSH |lm
Can 11)
00*00.SA am
Marl
10.01.61 I6.06.T6
At
11
11 1A.01.10 Tee High geake II fra poly-
worker Inrl
III aatecler* cleaning
Central rooe
1 ir
00.00*16 am
Hart
01.01.61 00.01.17
60
16
10 01.01.11 Tee High geaka 10 yra poly-
worker IncI
III auto
clave
cleaning
10/78 Conitrad Average eapoaur* ftrot f yra ISO ppa, oec >1000 ppu. Neat 1 yra av, IS ppa. la at. yr a* IS ppa
Average eagoaare fleet f yra ISO Rfa, ere 1000 ppa. Laet yr av IS ppa. cm letter of 11.01.16
II (HIOSN gtvea
* Caa* 10)
00.01. If Hacker
Rarg-
10.10.11 10.06.11
A!
11
11 10.06.11
TeV
High
3 gre unto-
baeaen
clave
cleaner
If yra
filter
operator
11
00.00.10 Dyaaalt Trotalert 00.00.61 00.10.11
If
16
6 01.10.71
Tea
t FTC Macu
lae tura
Antoelare
workor tor
6 yra
1
R&S 103512
IltPEKIAL CHEMICAL IHIHJSTRirS LltltTEH plastics Division
LIVER An||<iiniircou Canea - (Review Betel 1 Bhjf, 19RO)
(^rnanjF Sheet 4
Page It
11
1 2
11 13 1
I 11
1
ICOIHITRY Aim | NAME OR t HATE OF 1
| REFERENCE | IIIIT1ALS | MIRTH 1
| no
|
i1
J
i1
1
i
1
1 ||
11
1
i
4 | s 1 A | 7 i B 1 9 1 10 1 II 1 12 1 13 1 14 1 IS 1
C0T1PA1IY
11
X J________________1___________ J__________X
J1
X-
11
1
1 f1
11
1
1 1 FIRST VC 1 DATE or i ACE AT | TEARS OF | TEARS OF 1 BATE OF 1 HISTOLOGICAL 1 ESTIMATED 1
1
I FACTORY 1 EXPOSURE t DIAGNOSIS i DIACHOSIS | EXPOSURE TO | EXPOSURE 1 DEATH 1 CONFIRMATION | EXPOSURE | OCCUPATION 1
OTHER CAREER
J 1 |
1
11
1
| D1ACH0SIS 1
11
| LEVEL |
1 HIGIII.miTS i
J
Xt
J________________1
1I
11
j
16
OTHER coffiEirrs
CEWtAHY
1 1) 1 1*
i1
1
1i1
100.00.04 1 Lontfl
lUnldshut on.bo. mi 1 08.04.78 i
64
1
l
11
1
1i1
1 1 14 II9.0S.7S
1
1 Ho* 1
1
1 1 1
1 1
l (Not yet
Iconfinacil
1|
1
X XJ
J J1 X_ j
11 100.00.27 1 CUII
1 Ilia rl
111
1
03.I2.S6 1 at deatlit 1 Sit I 221 1 13 129.07.78
1 Ho* 1
1 1
l l
i |1k>t pet
confirmed
1 1 1 1 1 1 1 1
IS
00.00.19 Decker
Burghaneen I9.I0.S3 09.10.70
49
IS
10 13.10.70
Tea
(VKt eeye
IS)
Autoclave cleaner ami worker. Drier operntnr* Later shift leader
Ang I overcome confirmed 09/79
16
00.00.33 Oynaml t Troiedorf 10.01.55 07.00.70
44
13
20 07.00.70
Tea
HfRh Atoclave
Angiosarcoma
worker till
confIrmed
1964.
Iieader and
enter
17
00.00.37 Oynaml t
Trotndorf 01.11.61 14.00.70
41
16
II 20.00.79
Tea
Hi r,h Autoclave
tin Angiosarcoma
worker
confirned
* At tlie niOSII/lfEIIS KynpooliN In Bettwsita 10/21 tbrcli I9R0 Or Ifeher said there were now
ftrned caeea In Geraany* I preanme case* 13 and M ere now hlntologlcn)\\
firm'd*
IHFERlAt. CtWHICAI. INDUSTRIES UNITED rustics division
LinR h|lniKu Carea - (latlaa Datei 1 Hy 19M)
* Should this esse he reaanl Irow the Itstt SIOSI1 hsae It on their euppleawnterjr list relating to non-polpeerlaetlsn workers. JS 1/B/ll
rage it
1 1 1 4 1 t 0
f 10 It 11 ii 14
1)
COQNTST ado sr.rottNcc NO
NAME Oil INITIALS
DAT* or si mi
COHFANf ` FACTOIT
rust vc urosmc
OATS or DIAGNOSIS
AGE AT DIAGNOSIS
TSAIS or urosuss to
DIAGNOSIS
TEAR* Or EXPOttMtE
DATE OF DEATH
NISTMjOCICAL CONFIlttATlON
BST1HATB0 tirosOil
UKL
OCCUPATION
OTHER CAREER NtClll.lGNTS
It
OTIIKR COMMENTS
1TAU
01 (os moss
euppteentsrf list)
01
IS.0S.14
00.00.01 lf.04.tl
It
Of
0) lf.04.tl
lies
n.ii.if HootedIson Porto
00.00.lt ll.ll.tl
41
11
ot 00.11.tl
Tea
NiriMri
r?c b>i
*xtrader
rolyworker
Prlurjr turnout Mr h>v Wad perlcurd tua. Hot hoaageneoua with other cm
0)
1A.01.10 Solway
00.01.11 to.ot.ti
11
ft
11 10.01.11
!
Nigh
Autoclesner
*TOA et al
S fra
' papera at
Autoclave
thabroanlk
operator
suggest
tl pra
Farrars!
i
1
R&S 103514
IMPERIAL CIIENtCAL IHMMTRtRS LIMITED
plastics bivisioh
LIVER Angloearcona CiMl - (Review Bate) 1 Way IJ80)
VaR* M
1 1 J 4 Vc 7 S
V 10 It 11 11 14
IS
couhiet Atm EEFERENCB HO
KANE OR INITIALS
DATE OF BIRTH
CONTACT.
FIRST VC
dats or
ACE AT
FACTORT EKFOSURR DIAGHOSIS B1ACB0SIS
TEARS OF EiroSURE TO
DIACHOStS
TEARS OF EIFOSORR
DATE OF DEATH
HISTOLOGICAL CONFIRMATION
ESTI MATEO EXPOSURE
LEVEL
OOCUEATIfW
erne* CAREER nitmLtcRTs
14
other
comr.imi
JArAH
01
Toanjl
01.08.11 HItaut
sRr
00.04.33 14.10.71
S3
11
11 14.10.7S Tea PTC Aaaoc 13 jrre auto*
Horl
Toetea
aajre not clove
(o comnt
liwm<
cleaner
by Jar ETC
* Japan
IH4 -
Aaaoc)
Tinea
oeelgned to
InJIcataJ different
on IS.10.79 work alnce
aapoantea bad ill
often at health
3000 ppa p
to IV74
Japan Tinea 1S.I0.7S 4 Jepaneaa PTC Aaaoc latter of 3I.03.7R
01 so
01.OS.IV
00.11.38 IO.OS.74
37
17
13 IO.OS.74 Tea Not Ihiowr In poljmer-
laatlon work
Including
autoclave
cleaning
Japeneee ETC Aaaoclatlon letter of 31.01.74
CASES WOT TIT COHFIBHEB
Sblauo Sato
Shlgeo Tanaka 1
Sub
Nagoya
contractor
to HI tool
Tooten
Hitooi Toetoo
Nagoya
1HJ
Ho* ISAS . 41
it
Ratwyoehl Ono
HI tool To atoo
Nagoya
Oac IV6T
47
i4.6i.4l Dec 1347
Reactor cleaner 1V44-1V74
Fre-caoceroue JlaorJar of ll*ar Japan Tinea 13.10.73 not confined by Jaa FTC Aaaoc Japan Tinea 17.10.7S (aone figure# uncertain be4 print). Hot eonflrneS by Jap PTC Aaaoc
Japan Tinea 17.I0.7S. Hot conftrneS by Jap PTC Aaaoc
R&S 103515
: a?
1HPRR1AE. CmmiCAL INDUSTRIES LIHITRD
rustics MCIglOH
LITE* Angloaarcoaa Caaaa - < laa lav Ratal t Mat I960)
r,.. 14
I 1J
coinmiT Aim MFMCTC* tto
MAM m INITIALS
DATE or
rirtr
4 COHrAMT
1 1 0
10 11 11 1) 14
rACTOR!
riRST cc RKTOSUIR
DATS or RIACMOSIS
ACC AT MACHOS IS
irars or
RirOSVRC TO MACRORig
TRARS Or HCrOSURR
MTR or MATH
NlSTOUHSlCAt. COMIMIATIOH
ESTIMATED RXPOSURC
IEYEL
OCCOPATIOH
15
OTHER CAREER HICIILICirrS
It
OTIRR enHWHTS
NORWAY 01
All
11.11.11 Racak Kj4 co
Ilacoja
00.03.30 11.11.11
M
11 *
11 04.01.11
Tea
nigh
Tareoan 4 Autoclave aupecalauc
Cnnf InH hf Or HiIIbEmneofl of Nit* At AfHC Ht| of 9 June 19tB tfr f lan|Mi
itattf ttwt AH had boon Mealier of a
teen. TCH A rVC were Mfa In mm bttlldJftf. Hie VCH wit m4* fro acetylene
.
1 1
ihterial oirhical industries LIMITED ELASTICS Division
LITER Angleaarcoau Cmm - (Inl Data! i hr 1900)
R&S 103516
rag* 11
1 I 1 t 11 7 S
1 10 11 11 11 16
11
COURT*! AW) REVERENCE HO
NAME OR INITIALS
OATS or StATH
CODTAHT
7ACTOR!
TIMT VC nrosuRE
DATE OT DIACH0S1S
ace at
DIAGNOSIS
TEARS or Eirosms TO
DIAGNOSIS
TEARS or EErOSURE
DATE OT DEATH
RISTOLOCICAL COMHRHATIOH
ESTIMATED
EirOSURB LEVEL
occurATION
OTHER CAREER HIGHLIGHTS
SWEDEN
Ot HU
11.06.17 IcUMtt MavflH lt.0S.lt 10.10.70
61
If
IB 10.10.70
Ti
loljranlai
it f
mmn oowncim
I j
i
01 IL
17.11.11 KnamH Suirfaull 00.01.ti 00.OB.71
61
17
17 16.08.71
Tea
Nigh
VCH
product ion
Hr SJoeltn'e latter of 28 March 1978 eonflrwa BL wan a awioaer worker who hi hearIlf eapoaeif, probably earn wore oo then a mini reactor cleaner
0) Nl
10.06.10 IlMlWlI Suntmll 00.01.t7 1R.01.76
61
If
It 11.01.76
Tea
High
folyworker
0* AL
I6.tl.lt Innwtl SanAavail 00.00.t6 11.01.77
66
11
11 11.01.77
Tea'
Nigh
1166-1 MO
polfaar-
1ration
mrkit (11
fra) 6 1118-
1177 foreaan
(11 Trt)
In flrat 11 fra ol anplofsant boon heart If aipoaed. In 1176, ltaar ebnoraalltf and net main dlagnsaed. Data eanftnaed In Dr D ifran lattar IS.S.77 to CRT 1C
!
R&S
517
IHrnilAI. CIIEHICAL IKIHISTR IRS LIKITED
plastics division
LIKI h|lontCMi Caeee - (Itfltw Data! 1 Ihf 19
..[; -ii A,
I
Sheet I
h| 16
1 1 ) 6 )6 1
9 10 11 11 1) 16
13
COUNTRT AM) RCFERSHCR HO
HAW OR IHITIAIS
DATS or IRTN
COWAHT
rACTORT
FIRST VC strosoRR
OATS or OtAGHOSIS
ACS AT 01ACHOS1R
TSARS or EtfOSORR TO
0IACH0SIS
TEARS Or ssrosuRE
BATE or OKATH
RISIOhOCtCAI. COHr IRHATION
ESTIMATED
SirOSURR IJRTCL
OCCUFATIOH
OTtIKR CAREER
n iconCOTS
16
OTHER COWIEHTS
UK
01 K!
10.06.01 ICI
nillhoaaa 06.06.66 ej.u.n
11
IS
11 01.11.11
Tea
o rra 1966-1 TCH
(Foe A
(Foe 6
1961-8 Drier
Colllet
Collier
1968-61
rarer aejra
rapet
Autoclave
13.11.11)
ape
operator
11.11.11)
1961-66
Drier
0) UH
ot.06.); V
latry
00.01.66 00.11.16
)1
09
).) 16.11.16
Tea
High
Autoclave
cleaner
Expoeure 1 felted to let* - 9.S9
06 JS1
n.06.10 ICI
Rlllhoaae 16.06.)6 00.06.19
S9
1)
IB 11.10.19
Tea
HeAlaat- 16-J
Pre-ear fleti
hlgh
*ORRIns riant
packer 19)9-1! am,
11-6
vehtcla
Drier Plant alntenance
16-18
T9IvT<------------
Autoclave uorter
Ilah packer
18-61
ChargehanA
Drier
Plant
61-11
Poreoan
C 1/1 Plant
1
R&S 103518
-v> ^ ' i 'ijk*
imperial air.rucAt. trirmsTuirs lihitco mmcs division
LIVER Angiosarcoma (^ogh - (Rmtcu Dntet I May 1980)
m: Sfroet 2
Fnite 17
COUIITRT Aim
RCPCREHCF.
no
IIAIIE OR ItllTIALS
DATE OF R1RTII
UR 05
30.03.tt
06 1931
company
FACTORY
FIRST VC
EXPOSURE
HATE OF MACHOS IS
ACE AT DIAGNOSES
YEARS OF EXPOSURE. TO
DIAGNOSES
10
YEARS OF EXPOSURE
RATE OF DEATH
1?
HlSmOClCAL COMF1 Rl IAT tOtl
13
ESTIMATED EXPOSURE
LEVEL
It OCCUPATION
15
_L 1
OTHER
1
CAREER
|
menu cuts i
_______________ L 1
16
OTHER cntviF.trrs
Barry
OR.OI.5l 00.10.79
65
20
21 19.11.79
Barry
I $62
oonsr TbTT
TT
ir o4.0l.Bfl
1951-52 Polycleaner 1952-55 l.tci 1955-60 Polyfloor 1960-64 Poly Cliargeliand 1964-70 Charging operator 1970-72 Orlar operator
Greaaer on Poly Floor
X
|In their
(supplementary Jllat ntnsi)
|nrc atlll ft|UOtll)| (^se |02 Iron 10C0 (ulitcli haa keen |discounted in (the UK. IOCO (spread many Ipotjnwrs | Including rvc (onto fabric*. ITIie UK (Government IMedlrnl lAdvtsory (Service alan (know of rvo (further con|flrmd ASL leases In |plastlea (fabrication |workers but lit ta dnblona (whether they lever handled |PVC
I
103519
!i ''V*'
IMPERIAL CHEMICAL INDUSTRIES LIMITED PLASTICS DtflllOH
LIVER h|litcii CiMf - (Inim Ratal 1 thy 1900
*UE ijratca of data* DAT - HOHIM - TEAR
USA Sheet I
Page IB
1 1 1 4 14 7 o
1 to II 11 13 14
11.
COUNTET AND REVERENCE HO
NAME OR INITIALS
hate or BIRTH
coirAMT
FACTOR!
FIRST VC 11POSHES
BATE OF OIACNOOIB
AGO AT DIAGMoatS
TEARS OF EXPOSURE TO
DIAGNOSIS
TEARS OF ERPOSORR
DATE OF DEATH
HISTOLOGICAL CONFIRMATION
ESTIMATED EirosesE
LEVEL .
OCCUPATION
OTHER CAREER HIGHLIGHTS
14
OTHER COHHEKTS
USA
01 Curl
17.10.11 IPO
Loula-
01.11.40 03.03.73
41
14
11 03.01.73
Tee
farlta
allla
01
ll.OS.31 IPG
Louie-
11.11.11 00.01.70
17
14
13 17.01.71
Tea
allla
(Htosn
aapa
10.01.71)
03
11.01.11 sro
Loale-
10.11.41 11.11.71
10
10
to 11.11.71
Tea
allla
04
11.01.14 PO
Loate-
04.07.11 19.00.47
41
l?
11 07.01.40
Tea
allla
01
11.01.11 RFC
Loot a-
19.04.44 01.04.44
11
10
10 01.04.44
Tea
allla
04 1*7
ll.It.lB re
Loala-
17.01.41 00.01.74
41
It
11 14.07.71
Tea
Anatin
vllla
JonaaT
Pet Cleaner (Block Jane
1174) f 13
Pet Cleaner (Cf Block)
Dot Clcmr (Cf Block)
Fot Clttntr (cr aivck)
Fat Cleaner (Cf Otock)
OS Air Farce Fat Cleaner (Cf Block)
SoftInf Sterne Art net t tnr Acj of Sc Sjrop 1974 Mm Slock Jmi 1.7*74 P
Ref 1 Alee Rlock JAMA 1.7.74 PW
Ref 1 Alio Slock
Ref 1 Alee Slack
Ref 1 Aten Rlock
Ref t Louleallta Tinea 11.7.71 Retires April 1174 Alan Rlock
07 Charles 01.01.11 occ T laatl
S CharPe 17.00.44 00.00.40 atoa
00 04.01.10 CooSpaar Niagara 07.10.44 00.00.41
43 41
11 IS
__________ 1____
17 13.03.48 11 11.00.41
1______________
Tot T*t
Ref 1 Ref 1
ihprrial ciiehical industries mhiteo plastics division
LIVER AfliloiarcMn Case* - (Review Betel 1 8ey 1980
R&S 103520
eyetew of date* OAT - HONTH - TRAR
USA Sheet 2
Fege 19
1 1 1 4 3 T 0
9 10 It tl ii 14
IS
COUHTRT AMO REFERENCE HO
HAHR OH INITIALS
OATH OP BIRTH
GOHPAHT
PACTORT
FIRST VC RPOSURS
OATB OF 0IACH0S1S
AOS AT DIACHOStS
TEARS OP ERroSURB TO
DIAGNOSIS
TEARS OP EXPOSURE
OATH OP 0BATN
fllSTOLOOtCAL CONFIRMATION
EST1HATED EXPOSURE
LEVEL
OCCUPATION
OTHER CAREER IIICttLIGHTR
IS
OTHER COHHEHTS
USA
Of RcjnonJ 0B.tt.lt SRI
Lowta-
1S.03.4S 01.03.Tl
41
19
14 ll.03.T5
Tea
1000 ppa
Get tie
villa
ringvr7
Ref I ban wrong flgaraa ra rirat evpoaore. LonlavllIt Tinea 19.I0.T4, 11.1.75, I0.1.TS
10
IS.0S.11 Coodpaar Hlaiara ll.OS.31 00.03.SS
33
IT
IT I0.03.S8
Tea
Ref 1
tl
IT.OS.09 Coodpear Mlagara I4.10.4S 00.01.TO
St
11
11 IS.01.TO
Th
Ref 1
It Princti A IT.II.IS PIreatone Mtitwn lt.OT.49 01.03.S9
30
ID
19 01.03.S9
Tee
High 10 pra 10 yra aa Utltltp I
Ref t 4 letter
IcchaiR
Pi
reactor op. Service ope of IK April
(not cleaner
19TB Iron
- aeparate Orper op.
Rneaotl A Perk
crew cleaned Stripping op. to J T Seewelt
awtorlaeea) 1 pra prior of HCA
aarvlee la
tpro plant
It Richard Ol.tl.ll IICG
fl Chirli' 11.11.41 00.03.T4
31
it
IS 0T.04.T4 Ti 1000 ppo
Sward
ton
Clendenla
Ctiarleetoe Da Up Hall ll.T.TS
14 Dubtewa fabrication
caae
IS iniiMowe (fabrication
jeaee
I1
I
B&S 103521
>< iiv
vt v',,
1'4-
IHTER1AL CHEMICAL IHDII3TRIES UNITED rUUTICI OITISIOK
Ltm Aaf loiircmu Caeoa - (NtIn flata i 1 hj I960
* OR IjratM of Bate* OAT - HOim - TEAR
OSA Sheet 1
h|t 10
t 1 1 4 s* T 0
S 10 II 11 13 { 14
ts
couhtrt and
REFERENCE M
HAM 00 IHITIAU
BATE OT
ton
COHTAMT . FACTOR*
rim *c uroooRi
OATS or otAooons
AC8 AT 01AG008It
TEARS OT
irOSURB TO
DIACMMIfl
TEARS OT
Eirosims
DATE Or DEATH
HISTOLOGICAL COHTIRKATIOK
ESTIMATED 1
BSrOSDHE OCCUEATIOH LETEL
OTHER CAREER HIGHLIGHTS
16
OTHER COmEHTS
BSA
It Jaaee 04.II.1T ra
Loate-
00.01.30 00.00.4)
41
1*
04 IT.03.4)
T*a
Iboail
rlllef
Leoia-
IT
04.OS.31 ra
alllat
13.04.SS tl.IO.T4
43
IS
1) Altea
Taa
1**1-* TCH
potfwr*
lvtton
Eton t)S4
Title 4 In
enwarSe In
Wagoner
Aray anS otliar Taatinoay te
aeratea.
OS Senate
46-50 Amy
CoaftraeS la
H H Johneoa
Itr 0T.08.T8
CoaftraeS at Ire 4 REG caaa In H H Johnaoo
ltr OT.08.18
10 Chart la 11.04.10 ro
1m Lata 1S.0S.S4 00.00.IS
44
11
13 01.11.TS
Tea.
1) ;ra
Nit]p
Arthar
aataelaanar
8 fra
Ratal
Tyre Store
ylaetlclaer
4 Carhoaat
aparaIlea
ConflraeS In H H Johneon ltr OT.08.T8 Alan Rntllan Stone nag. 13.01.It
l
Tirol1
00.00.15 ucc
0 Charta- 00.00.43 IS.04.TS
40
31
11 04.04. T4 Taa 1000 Rpa
Chrlatlan
atea
(lataat
HIOSH
allaa)
Hlltlaaaport Sun Ceaette 11 June ISTS Charteatoe Dally Hall ll.T.TS
10
1I.08.1T Gnodfttr Riagara 00.00.SS 30.01.T*
SB
It
ts 10.01. T4
Taa
HIOSH letter of 1S.10.T*
11 Chaatar 01.0*.OS occ
0 Charla- 00.11.44 Karl? IT
4T
30
11 01.01.TT
Taa
tllnUa
atsa
IS yra with OCC at SC RatlreS Hewe raleeee ll.l.TT
R&S 103522
IMPERIAL CHEMICAL IHMISTR IE* LIMITED FUSTICS DIVI3IOH
Lives Angloearcoaa Caeee - (Rorleu total 1 fcf i960
*UR ajatca of dotca DAT - HOHTII - TEAS
USA Stoat A
Page II
1 1 1 1 1 1
V 10 11 11 11 14
"! "
COUHTRT AKD
sepseencs
no
NAME OS IHIT1ALS
DATE Or BISTtl
COVAHT fACTOST
rtssr vc Exrosuss
MTS or DIAOHOStS
ACE AT DIACROSIS
TEASS or sirosesE to
DIACROSIS
TRASS or ssrosusE
DATE or DEATH
HISTOLOGICAL CORE ISHATtOR
ESTIMATED Birosose
LEVEL
OCCUrATIQK
OTHER
CAREER HIGHLIGHTS
j 1
OTHER coHHFmrs
OSA n
01.10.11 la thla
OKI
la thla 10th l.oolaallla rtetlot
ll.OI.AI 00.0l.lt
n
00.00.11 Croat
ri tehbors 08.0V.lt 0t.04.ll
Anr lean Male.
Cheatcal
Cowpanjr
lmn Ina Regtater. Hot an ASL Cnaa
Ctotlaa Edward Hoora.
11.01.11 UCC
9 diirliaton
1MV
11.01.11
<)
hiosh
ranaa Iron regtater
01 .OB.10 l
1
T 00.01.41 10.01.11
n
11
IS 04.ll.lt
Taa
10
11
14 0t.04.lt
Tea
Leulovllle Time# 16a1.76 ealit he wee the 10th AS victim et Retie 1.ane of vhoa 0 M died by 16*1*76
to
IB
14T 11.01.11 Cholangte-
Hedliaa ta 1941-65 non- 1131-19 waa H M Wheeler
(Hiosn
aarcana
high for solvent
off and on
letter af
aja It)
(S Ranlnakl 14 gra
vinyl re*In labourer
IS.t.ll to
lt/1/11)
unit and
litt-li war J Stafford
4taperaIon have heen
It tree detalla
vinyl re*In* eapoeed aa anil Mrat reartor
Roaa Raoinati jletter of
laa fitter cleaner
114/1/1*
|helper, then 1943 became 1
ehlft
ehlft fitter 1
1 attitty nan 1946 became
ehlft utility
an 1
26.04,65
1
employment vni I
ternInated
_________________
tl
10
10 10.03.11
Ho
1HIOSH way wore
[(row ttolr
iraglater
!
j | | I
I________________
I
[ 1
Jr H Whaaler jletter af JlO/l/lV and |Roaa Ranlnakl I Uttar of | It/lllV
1 1
imperial chemical industries limited
rustics D1TISI0N
LITER Aii|Iourou Caeee (ItilM Betel 1 % 19*0
IK of fitu DAI - NORTH - TEAS
USA 8tieet 3
P** M
1 1 ] 4 3S 7 0
* 10 11 11 13 14
13
16
COUWTRT ASU RETESEHCR DO
DAMS OR INITIALS
DATE or SIR1D
COWART
FACTOR!
FIRST TC UrOSURR
BATS OF DIAGNOSIS
AOE AT DIAGNOSIS
TEARS OF EiroSORE TO
DIAGNOSIS
TEARS OF SRFOSURB
DATS OF BEATS
HISTOLOGICAL CONFIRMATION
ESTIHATED ERFOSURE
LETEL
OCCUFATION
OTHER CAREER HIGHLIGHTS
ornEit coHmm
USA IS
John Barrj 07.07.13 src
LoaleTlllO
03.10.47
00.00.77
(P * 1 inn after fnth)
31 (fulb)
IS (death)
IS 11.01.7) T.a Expoeed la Tarleaa John
aoaa Sagran to FTC
to 11
planta fro.
chealcala cold rooo to
tut aatn paate
expoaere recoverp to
aaa to TCH, FTC charging
ftoliUf operator to
high
pa ate
charglog.
Ill Aaguat
l*S3.
Tarolnated
aaplopaent
Jan 1*64
R Ra.lnakt tetter of 16/1/7* and Prof. Taaborro latter el */l/7*
17 7 L
11.03.IS ucc
Torroot
S Charla- 01.07.41 30.11.7B ItM
*1
37 10 1S.I1.7I herafltti
(HIOSH
(N10SN non
i|< 17
tape con-
and G
flTMd)
Dalis Hall
H)
High
Operator to 10.10.76
Exposure In R H Uheeler
balk end
Itr of 4 Jan
diaper a Ion PTC 1*79 and
aanufacture Charieaten
Dallf Mall
30.11.78 and
R Raalaakl
16/1/7*
IS
11.04.17 ucc
1 cfcarle- 1*44
1)77
SI
33
33 03.11.78
T.a
otoo
*
11 KmIhiM letter of
I 11
R&S 103524
h'
1HTER1AL CHEMICAL INDUSTRIES LIMITED ELASTICS DIVISIM
LIVES Anglaaatcoaa Caaea - '(Saalev Bate) 1
19M
rag# 11
. 1
COUItTRT AND BBPEREHCE ITO
1
HAHE Oil IKITIALS
)
nm or aiRTit
4 34 I 8
9 10 It 11 13 14
COHTANT
VACTOBT
msr vc EXPOSURE
DATS Of DIACOOS1S
ACS AT OIACROS1B
TEARS OV EXTOSURE TO
DIAGNOSIS
TEARS OP EXPOSURE
DATE Of DEATH
HISTOLOGICAL CONURHATIOH
EST1HATS0 BirOSURE
LEVEL
occupation
13
OTHER CAREER HICULICIITS
IS
OTHER COKKUTS
TUCOSLAV1A 01
OJ.01.tI Juga
Split
00.00.33 08.04.13
3)
10
ID 08.04.13
Tt
VI all
SARIC at at paper En* Health Terapectlfa Yol 11, pp INV-IV1 1V1S
01
13.11.31 Juga
Split
00.00.30 11.01.13
41
11
IS 11.01.13
Taa*
Vlall
0)
II.11.31 Jaga
Split
04.0S.34 11.01.IS
43
11
11 11.01.IS
Teo*
Vlnll
TCH
VCH Prodaction
Mn his letter of 3 Oct 1970, Ur Splrteo of HIOSII changed the ititM of Ceee 01 to VCH production e*ployee Ur Splrteo atao notified new Case 03 alao VCH product Ion worker
i
ji ir
t 1 11
R&S 103
!() 'n
TABLE 1
Page 24
Incidence of ASL Cases Per Annum
By date of diagnosis
By date of death
1955 6 7 8 9
1960
1
2
3
4
5 6 7 8 9 1970 1 2 3 4 5 6 7 8 9 1980
Total
1 0
1
0
0
0
1
1
0 1 0 1 3 4 2 4 2 4 9 7 10 13 7 (excluding 2 Removals) 8 4 1
84 (excluding 2 Removals from IIS list + 2/3 vague Japanese cases)
1
0
1
0
0
0
1 1 0 1 0 1 1 5 3 2 3 5 6 6 11 12 8 (excluding 2 Removals) 10 4 1
83 (excluding 2 removals from UR list + 2/3 vague Japanese cases)
11.B 1 Does not include Italian 01 but does include German 03.
2 Does not include Japanese suspect cases. Since post mortem examinations are rare events in Japan, confirmation of ASL is a problem as indeed is its discovery.
R&S 103526
Distribution of ASL Cases by Country
TABLE 2
Page 25
USA Canada W Germany France Sweden Yugoslavia Italy UK Czechoslovakia Norway Belgium Japan
Total
24 *** 10 17 ** 13
4 **** 3 ***** 2* 5 2 1 1 2 84 (allowing for 2 removals from US list due to mis-diagnosis and omitting 2/3 ill
defined Japanese cases reported some years ago in Japanese newspapers).
* Omit ItOl - atypical case of PVC bag extruder. ** Includes CE03 aerosol can filler.
*** Includes US17 - man still alive after ASL diagnosed 11.10.74 but removes Cases 24 and 25 where ASL not confirmed. **** Includes one monomer worker. ***** Includes two monomer workers.
i.e. North America
(Western Europe ^^kst of World
34 (excluding 1 alive and 2 earlier cases removed)
43 (includes G03 aer^Ml can filler) 7 (excluding 2/3 st^ftt cases)
103527
TABLE 3
Pattern of ASL Cases by Factory
(a) W Europe
Of the 43 cases in W Europe, 35 have occurred in clusters at 10 factories. Of the 17 German cases, 15 have occurred In clusters at 4 factories.
ASL Cases
Kemanord, Sundsvall PCUK, Rrignoud Dynamit, Troisdorf RP, St Fons Wacker, Burghausen CWH, Marl ICI, Hillhouse BP, Barry Solvay, Tavaux Lonza, Waldshut
4
5
6
4
4
3 2
7
3/
2
2
35
(b) H America
Of the 34 caBes in N America, 31 have occurred at four factories out of a total of 53 factories - in N America 46 plants have not had ASL cases.
ASL Cases
BFG, Shawinigan BFG, Louisville UCC, S Charleston Coodyear, Niagara
10 11 I 67 4
31
(c) Rest of World
The 7 ASL cases are believed to be in 1 cluster of 3 and 2 clusters of 2 cases.
Page 26
*r
R&S 103528
,
TABLE 4 Latency Periods (Years from first Exposure to Diagnosis)
Pa go 27
W Europe
Ho of Cases
Total Years
Average
Belgium
i 18 18
France
13 298 22.9 *
Germany
17 305 17.9 *
Italy
2 37 18.5
Norway
1 22 22
Sweden
4 106 26.5
11 America
UK
5 108 21.6 43 894 20.8
US 24 557 23.2 *
Rest of Uorld
Canada
10 204 20.4 * 34 761 22.38
Czechoslovakia
2
31 15.5
Japan
2 39 19.5
Summary
Yugoslavia
3 7
65 21.7 135 19.3
'
U Europe 43 894 20.8
N America
34
761 22.38
Rest of World
7 84
135 1790
19.3 21.3
* Of tt^jj^nintries with^ 10 cases, France and USA have avera{^|^tency period above world average and Germany well
*% T\jj/
f w. Asl
TABLE 5
Page 28
Annual Incidence of ASL Cases (Date of Death) by Geographical Area
1955 7
1961 2 4 6 7 8 9
1970 1 2 3 4 5 6 7 6 9
1980
Western Europe
1
1 1 1 4 1 3 6 6 6 8 4
1'
*43
1 I
1 1 1 t 1 1 1 1
1 | | | 1 I 1 I I I I I
1 |
North America
1 1 1 1 1
5 2 1 2 1 3 2 4 4 2 2
JL 33
Rest of World
1
2 1 1 2
7
11
I
Annual Total
|
11
11
1
111
11 1
111
11 1
111
1t 1
13|
13 f
121
13 1
15 |
16
|
16|
1H
1
1 12
f
18
|
1
X 10
1
J4 /f 1 1 i fjL*\
\ 83
|
* Includes G03 aerosol can filler but omits It 01 bag extruder