Document M5Z8za4mkgbLGJ7e7wg4qDbM

Tc Monsanto Mootnto Company BOO N. Lindbergh Boulevard St. Louis. Missouri 03166 Phone: 014) 604-1000 March 27, 1969 -.ORGANIC CHCMICALS OMSION Mr. Fred H. Dlerker Executive Officer State of Callfornla-Resources Agency San Francisco Bay Region Regional Water Quality Control Board 364 Fourteenth Street Oakland, California 94612 Ref: File No. 2119-1075 Dear Mr. Dlerker: This letter Is written In response to your letter dated March 7, asking several questions concerning poly chlorinated biphenyls ("PCB") manufactured by Monsanto. Responses to each of your questions are set forth below, numbered in accordance with your letter. 1, We have recently contracted with a consulting laboratory to undertake fish toxicity studies on PCB's. Because of the low solubility of PCB in water, It may be difficult to obtain a 96-hour TI*,. Depending upon the results of the Initial studies, we may conduct 30-day exposure experiments. 2. Attachment A shows the general physical characteristics of PCB. Information set forth on the bottom of these pages shows the results of acute animal toxicity studies showing the oral LD-0 In rats and the minimum lethal skin dose when applied to rabbits. You will note that these results were obtained using un diluted samples or as a corn oil suspension solution depending on the viscosity and Bolublllty of the materials. MONS USS311 -2- 3. * 5* Attachment B shows the results of studies of chronic Inhalation. You will note In the table describing the properties of various PCB's that the liquid materials have extremely high dlBtlllatlon ranges and that waxy or resinous materials have to be distilled under high vacuum. These data attest to the low vapor pressure of the materials at ambient temperatures. PCB finds primary use In applications requir ing chemical stability, good dielectric properties, fire resistance, low volatility and water Insolubility. When used in dielectric fluid, PCB is hermetically sealed in capacitors and transformers, designed for 20 to 30 years life at temperatures at or near ambient temperatures. Plasticizer PCB Is found primarily as a plasticizer for surface coatings such as corrosion resistant paints. Industrial adhesives and as a sealant such as window sealants. These applications do not Include automobile tires, or floor tile. These applications of PCB emphasize Its inertness and low volatility to provide long Bervlce life for the product without loss of flexibility. In normal use, PCB plasticizer applications are ambient temperature environments presenting no special health problems. In view of PCB's chemical Inertness, we would anticipate no problems associated with the environment from refuse dumps. PCB finds further application In Industrial (excluding aviation) hydraulic and heat transfer systems. As In the case of dielectric applications, these systems are designed for essentially Indefinite fluid life. 4. PCB Is essentially Insoluble In water, which Is a property valued for most of Its Industrial applications. The solubility of PCB varies with the number of chlorine atoms. Solubility In tap water at 25C. is as follows: MQN3 088312 3- Materlal Solubility In Water PCB - (42* chlorine by weight) PCB - (48* ........................... PCB - (54* "" " 203 i 10 ppm 106 i 14 ppm 50 t 2 ppm Thla data Indicates that the most highly chlorinated PCB's are the least Boluble In water. Annual consumption in the Bay Area Is less than 500,000 pounds Tor all PCB applications. 6. It Is a long standing policy at Monsanto not to disclose information concerning our customers. Including the customer's name. However, we desire to cooperate with you to the fullest extent practicable in this matter. Should you desire to visit typical PCB users we will be happy to approach our customers to arrange a visit. 7. We advise persons using PCB products to take normal precautions associated with handling most synthetic materials. If accidentally spilled on hands, no serious skin Irritation should occur. However, PCB has a solvent action (similar to paint thinner) on the fats and oils of the skin and prolonged contact may lead to drying and chapping of the skin. In the event of contact, the skin should be washed with soap and water. Saturated clothing should be removed and dry cleaned. Spills may be cleaned up with rags, Bawdust or absorbent clay. Eye contact may result in painful irritation but should cause no permanent damage to tissues. In the event of eye contact, the eye should be flushed with large amounts of water. As with all eye flrst-ald, a physician should be consulted. To relieve Irritation, physicians have used a 1* Pontocalne as well as ophthalmic cortisone acetate solution, or castor oil. Infrequent exposure to PCB vapor should not cause 111 effects. However, prolonged exposure to high vapor concentrations should be avoided. mqns oaaau -4- After many years of experience with PCB, It Is our understanding that cases of harmful effects resulting from the Industrial use of PCB have been extremely rare. We believe this Is due largely to low volatility which reduces possible Inhalation at ambient temperatures. We sincerely trust that this answers the questions con tained In your letter. As further Information becomes available In which we feel you might be Interested, we will pass such Information on to you. YourB very truly HSBspep Attachments BCCi r. S. Park E. Wheeler/J. Garrett Olsen. P. Benlgnus IT. Wayohoff D. Pogue N. T. Johnson V. R. Rlohard Director, Functional Fluids MONS 088314