Document LpdVy30ooXn5V5qRap9Z5GJrX

Copie? to: E. I. du Pont de Nemours Company Haske11.Laboratory for Toxicology and Industrial Medicine HASKELL LABORATORY REPORT NO. 43-78 AR226-2869 M aterIa l Tested HaskelI No. 11,921 Sample Ready for Testing 7-20-77 Other Codes Material Submitted by Organic Chemicals Department, Chambers Works 333 33 EYE IRRITATION TEST IN RABBITS n03 Procedure: One Ouodre.l.l lllgreee of waxy test rabbits. Twenty seconds after contact, ^ . T * d coniunctiva were made with a hand-slit lamp at one and T9X 339 ^^5'^ day of treatment. ** The separated oil was remixed well with the waxy solid Itatn were used at e ^ n a t . o o s after the >33 s5.' si 5 100 mg waxy test m ateria I r> 100 mg waxy test materia I Not washed Washed None None None Redness: Mild 1-4 hours. SwelIing: Slight t-4 hours. Discharge: Mild 1-4 hours. Redness: None Swelling: None Discharge: None Company Sanitized. Does not coniai / 3 2- - JQ.: ^ ^ ^ T P r o d u c e d transient very mild conjunctivitis with no cornea! An eye dosed with the compound and promptly washed had no ocular effects. or iritic effect when tested Both eyes were norma! within in a rabbit I day. any Although eye contact. only transient minimal ocular effects occurred, good hygienic practice would be to flush copiously after j Report No. 43-78 i D2te issued: February 17, 1978 * < i> > >$ Report by: A r n > Approved by: Doris F. Edwards I ____Toxicologist ' ' I'' J U - / ( Neil Krivanek Chief, Dermal and Ocular Toxicology Section