Document LpXMnwLK0vzneo6KJ41O1we9g

-r PItani Pltqws: A Signpost of Asbestos Dust Inbalation t Wdioko ttrfint. M.0- door*# Joeoeaan. U.O. and Jir S. Ooraanaor. M.O. The (Moral eontarnimrioti of tbs urbsa u- hsvo boon iapdeatod. but tbo Utbost nu of mospboro by asbonos Sail lui bottoms meetsrm oeeurt wnb satbopbyiUlo.* manor of pobtte eeocan. tadusrritl asponr* ot ta tddiriaa. otbor ftetsn neb a tbo dto ud werkan to this San is alao oidouraad. Th asturo of tbo |ook*k deposit of tbo ubonao ' ratdickfiu tad othtr pbyiiataj iheoid bo fs- may bo iaporttat. For sxaapia, ia ta miHai with tie occupations k wbje* tsboties ebrynde mitua* sroao of Qaoboei tbo oeeur- dun exposure ocean tad ibeaM bo mri that rmca of piourai pkqun d> rniaon io coausoa ia ubesws ii used k sort (tat 3000 soomaarcai soao miaos. rvo !a otbon, tad sbsoat ia oooof Kw. IS* major out fer failure ot pobik tbo Itrpon auaoa aat to* dfcuat beta tbo health ifocia to eootni isbottom is the loo* oibors." Ia seooeaupatkaaiiy sxposod popuia- lotoot ported (oft* 30 yosn or aero) boron* tkos. ponkakrty k Ftaiaari. tbo prorsioaeo of tit f qrt otpocort tad tbo tp> pioanl pUmas roiaua m tbo pratnity of pasraco of o*t dbeoso. Tbo disease sow bo rtsidoaeo to tortsk mists anas, tad tbo sir il* dfcaoeered *oi midsud by edaimii is M poliatod that ovoa eactio art eon- potato dark* or bedbre Work Wr H. liteo tsrtaatod.^**1* Skaiariy, pia^uts bsro booa tbo 1930*. fto prteaatteu *oro tarot a absomd ia a o*daaitani popaiatkos* sad protest oorkon from t*k tastes don. Thao it ia tank1' ia anas ia wbkfe tba nil is eestaa* liOowt that a proroat tsbeotes dan dta*os* ia iaatori wick nhioiifana materials tbo yoat 3000 *o aan rno*tdM its citrsetaratte rsdtetrspkk appemoc* soar sad taka PATMoanaid amo fatmocouv .appropriate aaasaraa to rodaoo txpotaro To data, a* touily sadofsesory tspisaaiieo whomrtr oAdnto ot tko disoato is Iboad. bss baas dnskpod to opiaio boor tbo pioanl r~Altbooak iibtoi dan teialsste is mi tbo] I asio booio at stoonl piapnea it O <rru0*i7 toaj /mas* maaaoo. Tbo moorarioo bocwiM pioarti rtoorino that rosoits ia pUftaas dorPops d roocoou a <Oa mOaiortno of ttOooaoo An sad porOeiao. AtOossoo bodlso boro rorsty ba piaqsos tad oeespadoeii or mapiwwl fooad is pisqoas.11 but ssbostos Sbon may bo asbestos dan otposoro has ban amply oo* proooot. Kowmror- tbo lack of ssbostes fibors in Snood by pepoiatte atodtoa.'Tha proraisocoef piooaos moatkaod by prrhoos iarostkators bas pioertl dtaa**s nos radtn*rtpbt has boon iarpoiy boos doa to madapoato toebakum11 By ibovo to iaaroaso ia rteadM to tbo otnuad maoas of rooootiy dorokpod toebakpoa of Soso of uboswa. tbo sfa of tbo pattest, mi tbo trissnitiko tioctro* mkroscopy. toisemro lon*U of Urn after bridal oaposoro to trot tiocooa dgfrsaiao. ud arisnoboaicai bonao.k,MU* Tbk is tetbar eooftnood by s naiysk of portfeks. maay mail ruonucro- furty irroo* errtUstea botwoaa plesral soopk sabosaso Sbon ia piotrai pionso* bare piaqtu* teod o* poouooatoot itadks* u4 s booa idaadftod uopurreeady by morpboiofk. history af prsrkaa otpqrui oaoaartkl stnoanl. ud ebaattkk Radka.1^* It is of typoa of tobonos-*** Aft nrtedao of uboatM ktnost that tboso art aro ooaoostmol ia tba ealdftod ants tboa ia tba Sbtooa to#os.J .As* bans# Sbon an also coaunaoly oboorvod ia at* tua* dssuosof paduts ktb piapaoa.'-u *. MSa lm MJu htfmmr tf XmMtg. UC-iOC MtMtM Cam Lm **** CM* One*o lioOn, MAi kfww f XuMnkrt. C<C-U3C MW Como. See .a<a Co*C /op 1 OorOmn. M.0U xtaOuo fr*fm*r of tmtfiip. HC-USC MrmMCmr ImAmgMm. CM* labalad Sbon too*or (baa tboso that eoa bo pbao*yto**d by bisdoeytts or put sails moo downward tad ootward at tba lusts. This typo of jnrtuoaosl tsavonaat (m nostul ia other paoamoennktos) is iaSsooead by tbs aiac- kA> ZOOM OoN to nHwiQ * t MkoMP km Jkft. bn oxr. Pooon Of XtMMro. UCuse JToOioO Coon, /as <p. Show Sown, tw -** cm* mi tttmf Ozom 4 Strmmm. I*. SS/P.OOjy-JMX dues of tbroo rarisbios: tbo prom* of '.am. ibarp uhottsa Sbon; tbo uft. caiiy poaenrod pnlajooary itnebtrot sad tbo oooiuac raoaaa of tbo leap" :t? OUP 0934505 DU 036931 :t A proposad thry of pathopoaoak of piattrti pit^aai I* u (Wows: Fbtn. particularly -tha [oaf soat. tctd to am towtrd tha laag pa rish*y, soaa 1*B| tha Iaag ad rtaehaif tha paratii piaan tioag tha chast wrt. diaphrags. ad padvduSi Malt d da uargaat u* baato* dbars pass through tha tott tausa ot tha ktaraottai naadat ad omacolar portaea of tha diapdnfau Othan art kockadrt by tha hard uaaa of tha nbt, tha daait Shrou tjnu of Am tadhaas poraoa of tha dtapOrsgiu, or tha pari*' cardhua. Tha timiinrina of pisunl piagaoa u thaaa bub. paeaJly poaurioriy tad laxarafly, is ala iaM ta bo tahtacrt by tha roakat -'Tit rtmn in tiTM** aashsakrafy a tha aariaaai Jinn ad ato practically trror taaoumiarad ia tha apacaa oT tba laaa. baiow tba 11th rtk a tflaraagaof taa castaBOnatc aqaiat. or iptmoriT soar .tiu ai earthaaaanThaa tha piaqaaa raMit from oaSSeffar oiiar raaasM ta tht utaaaes ft* ban. ladfcridaai saakartTy ia prabahty tiaa n important factor ia thad tonudea. Craasfy, tha piaani ptapaa it eharwadnd .by byahadad dlsarau karaud pny whita at paarty araaa tamMag tha pariaui pimra (W*. IX Datpiu nrykg dear tad shtpas. thapasan of tha piagaaa ia I'^ititda. Than k a flat or slightly aaaaat strfaaa. with staap adgoa rkkg tbnpdy boa tha sarrotadhtg aoraai plant. - tad bara tad thara roaadad aoaads. with toatwhat ovarhaagfeg adgaa.14 Tha thnfc pita* rai piagaat in typiaai ia sppsariam, ad tha dasais aapahaa is m bortag or agar Wag IZiuxtrpui), u ia saaa aa saraaa aaubriasa1* MjcroaeapicaUy tha ptwpat aaaahtt aaWy of svuaoiar. tsattuiar. hyrtirtad. laarissad. ia* twnkftiBg aaOagaaaaa ihai. tartly with ia ortoatatioa panfld ta tha artaa Carta rtaa* iag shows dues laairtaa baath tha piagM, ia mancaay with tha sarraaadkg aamai pariaui piarai aaaaattfoa Usata. Tha ptaani piaqas a. ia fact. aat a piarai piagaa u til. bat nbpiaorai a atragiaani. tarty ia its form*dea. tha aaathattd art thdag of tha serosal pariaui piaua tahsa oo pan a tha procau. bat taaair t*u u t potato nrarkf.1** Tha growth of tha piagaa is siow ad is of noaaasd* sera typa. Thu adhatmu batwaa tha iscan! tad pansui pinna art nrauily thaaat. ?".iqua am MKoeNMN Hat. ferautka aa tha ahavil piaan ia nra tad that oafyrtartti. k t high pngartaa of pUgaaa- U k of tha dys trophia typa ippaarkg ta gnaaita tioag tha ooana af tha aartaiar art dagaaaratad oaOagu than nd naiikf thraptiy dot tha thaaraai oaaaaatira tkaaa ahaagaa aua aaraai piaarsi dtsan iueioa*Amic Agners Tha. rirtaartohia shaatsa k tha platra hsfflaawwkkaat_a_b_at_t_a_a__a_h_t_it_ti_oa raaiit bon tvjas afaariattiaiaar| ruetias. Mott frwwut ia tha looakaa. liamaa. pititauiQct,, naooth or aadaiar in of kaani thkhauag that arraspoads a tha pathaionaatty obtaSai ~r^Tr-rlua. MMaMatfi"lau oomtaoaiy, a ooa* ipaahc ataturt diAua piaani tbidtiaw* aty bafoaad. DOf 0934606 DU 036932 njuiui auoua /foarafepCad datartad. aad ttoair praralaaca dans? Ufa to oadanscfcutad. Oaiy a aufl pareaupt of aarty pinaan idadlnd at paanorua uta> action ton kaaa dataatad aa reatiaa PA rv dfepraptoa.' ta (Ida prejaadon a aU-dniopnd piacral plaqaa rmlu la ticker a pro/ttr pnaaatirtna or ta aa /act pmaautioa. Tha piaqaa to profit appaart u a Uarpty narpto* ttad whitt haad of *atar dtasity, mujaly porailtotop tfcn laaar narpia of tit laitrtl ctoirtato wad. It to imaffy aec ofcaeorad hy tit avariytoy mfaiar toutoow (F%. ZV Tba vary aarty plapaa a ikow oaiy a (ilia wfcfea linn of toaraasad daaairy adfacaat to tot rib toat lua tnaa Ukmd a a Siapa.* Thru Ac pnsflU Uaa oi tarty piapaa tormauoa is tasdy ovariaakad ad oftaa datantad otdy to raua* ipaet CF1*. 3\ panieuiarty whan it raaaobia toa aamuf toaar fft arfaca. As it toiartas, ic bteooaa aarakat aaf tad modtrtttly pratabnraat. add upnrtof laparior aad iafarior otrftos typical of u attnpiaunl lasiaa (Pip. 4). A ptaqac nttff otraodt raraeaily more tain DU? 0934607 DU 036933 Ul DU 036935 MiaBffgjui--grgatMiBaiisijfciijmKgitawBtgts 2X2 (oor iat(TtpeM.M<< Tht thicfcaota of tho plequoa variao from I aua to ocrc this 10 mss. but it ts usually a tbs rcagoof M sub. Hma tn asatUy bdtitrti sad often symaotric. Mon aomntcttjV thay lla aditent to At 3th. 6Lb. ith. tab Ith nbt tad istartpooaa.M As sutad sarij*. avolvaaat of tha tpieas or oostopfcraoio aagisa is mtromky rtrc Earty, tha piaqus may be taUtxry, bat las* savors! dia* tact aooeoafcont pUqtos u* oft* farad. Lota than 23 % of attinaeitfcjdmoi hart mdmcx of accaaoaayisi ratarstltlal la dUane" ixrfato plaunt tLdcnssg a ttroqent mdTo cbaracurizad by wforrn bonogMeows denary, by t task of aoduiariry of amour, tad panics* lariy by tocoapuyisi aottaphrtUe eagle abiitwudoa. Ploerii (Autoe is quits rue. Plaques is prodle arc (tusk lata aaaeoaly oa the diaptanua sad rwaiy an <fca porirantiii aar* fact. harc they appear u ns or more Is* cabas* otpvuioas os tha aotaai aorr rfaaa of then strueturoa. Thosa ara asoaily tanas* paaiad by tddMasai piaqan aieeg tfca Lateral thondc *iifc they art aaidotB iaaiatad lama. On tha dUphragn thay ara tins* at asm dtauace from tha nqlae. Le. keae M tha Jtatnl trades. Whn laaairtfai. thay man be diffarntiaud boa normal (acaOspiag) or sfa oermsi varistisas ba dUphragsMiU mo tear (f%*.2aadT> Tha aanod cypao/ ratiogrspUs praossudas. 'tha tn foei pre)actios. is that of a fast H*da> Saab vkUkt opaatty or shadow.1 Ttai alas oc* car moat eomsvoeiy is tha regies of tha 3th a Ith riba (Pig. JA-CV Thay ara rsrky dotassU bn at tha madiai half aft them, bat they are cfiaa obrioaa *t thay orarito tha latani upset. ahara thay ara mart ahlhpia to tha t* ray beta tad haaaa absorb mors radtwin. Tha n foe* plaque rsruiy appears aaifarmiy rounded: it sfcawt t peripheral irrtjiilarity of soatour that has ban Uknad to tha Maya of a map or body last 1 tanas af tha fhutaou is outline. it is sftn dhaiiaaad at n artifact oa a impie i adlogrirh paritaanaa n repeat aaaarf* attioa prarnt this arrar. Iwaiii it is Sat. it is loss radhpeqae that n aotpalacowy aodaia of tha lane disaster. Cartful abeam* doo snowy that the ar/aer shadow it oftn lass dtaaa cntnlly, ooiikt tha sort uniform boo* (annus density of tht rotted or oral is* trapulmoaary ooduii Whn multiple. the add* umwt. .Acetaort, mo uascutCN rttial m foot plaques art oftn separated by a bud of aonsal radioiuaaot lug. The me of oblictaa rim is ttroaglr roam* mandel ao< only for ooahrmauoo o( wtptcttd olauril 9itaut formaflot but also for dotoction of_|ddltiotal placets-or pi card thickening aaaaapectad a tho PA owiactioo (fit. ;a~ci Wbh thtM views, tha fie* pUqaa *dl oftan praam a prodlt appearnc* Tha tu of Sso- ratoopy thd spot Slatiag to datarmiaa tha proper obtiquiry for damoejgukty a plaque m praile is of great raise. ObUqae views bare eoahnaed the ftat that piaqaet spere the apian tad tha aestophmie tsgiaa tad are moat flragandy Coaad tioeg tha posterior radaadea of tho oootai pioara. Thoy may mood latmmily tad uitrtorty u far u tha ootiai oartiia|s juetioa. bat thay raraiy sveda tha rfb tartaagta. hanatiaiu tu aoadmtd tha pariatai loeatioa of t piaqaa asd bu damoaitratad tht thuaea of adhoahma b train tha riaaarai tad pariatai pieara. Adharioos. 1f praaaat. do aat aaaar ia arm af ptaqua torma- tioa. Ttawgrtphy is of Unit uatauaco is d--waarranag aaaaalatfad pUqan ae As aoo* paak Uadawa tf offatmt tike taad ta War m the IMadaad ihtdawt af tha pUqan Coo* pnnfead asiai tonography bu doaotstnud the piiqa-u Ultruoais at--rtaatiaa has ban otfhrn u a mere sauitjra twrielky Sac datac* tin af piaaral piaqaas. It bu ban sagganad thu piaqan laas thn 2-1 ra thhek. which art ousted by radfagnphio nntmtina. an ba de> tnud by aitmousd." Pfagaar lawr marmet rnmmmfe tkoten*. Tha aanMoad tWaktua af tha daman oampria* iag tbs riaanoi tad pariatai piaartl layon thu pgraasd tha --id last h Ml ordiaarty aanarsMa os tfca rs^agrapb Tha oarmai pinraidanaanaiauofadegiolaywofmaBO- thoiirf cada asrnfcn aorfaca of a small anaast of fhroaroolsr daasa manuring lO-JOa is thwkaotii Oa tha raatisa PA projoetioa a vertical tn of nur dnaicy may ba mob. motacssn puthedng tha rno&ol aurfsao of the Srti three or (bar riba ting tho latani chorees wai Tbia vortical Ike bn varwuly bon caliad tha uiapnina ihadaw, tha piaurai thadow, tha piearai Iks. tht pinrad aurgiB. asd tho pietrtl stripe It it ooetnbatad to by a oombaieaoa of sueda (wbntui ud iatacoauib tho araoiar tiaaua af tho aodothortcia fuctsk ud. to a DU? 0934610 DU 036936 --/ paatar or la***r ertat. d*poa of fat. TO* tharp madia! mtrgia of th* shadow it boat ita *ba th* t-rty boua to taagadai to tha surfis* of t*o turns** sauaat thi* Uaitow. Tbit aormai pimni shadow meritsa* a width u it 3 trtcad supxtoriy ward th* dm rib: it uaoahy tapori rapidly iafxtorly, bcoai*| iaporciptiblo boiow th* lord of th *th totxattai spue*. (a tho PA projoctio* th* thtdcaou of th* shadow jg ao*r grraar thaa 3 aim: boworor. ia th* obiiqaa pro]*caoa this aormai piunl shadow * *idr. rarytog from 3 to 10 aim ia th* am tad somewhat ln ia woma.* Oeetmsaafly, * rry thto, btrtoy pxttpcfbi* da* may b* M*a madid to th* iwr half *f th* lattrai tharao* wad* I com hat arbttrarty baa dtiigaaiod u th* masJm**t accaptabi* thicks*** of thia aormai piarai shadow btoow th* lard of th* 4th iair* osatai iatanpac*. ,Tb oMtai slip* of origm of th* sarrtou aotartoe ud aunai thdotntoai obtiqat amaaia bar* a chariciartotto ratoegraphto pat:arc a rhythant stpaaoa of shadow* bacwoaa at** eaator* iatarooatai spasm (Fig. (V They ar* moat coauneoiy riaibi* **r th* Ith rib. but th* 7th rb ia aia* afftctad. aad oaautoaaHy ad of th* rib* from th* 3th to thw 9th aro bi*h*d. Th*y tppmr u ohm no dbtton ubagator shadow* or a aoahtoarinw of two opacdtoa * ixrimpoaad. Thoy showid aot b* adatakaa tor muititooai piapata, which asay aiaa show a sorim of shadawc Maidpio ptsipaa aro asoro likdy to diffor from *aah othot ia shM ad ship*, tsaiikt taaaai* shadow*, whtoh tr* ttsatily oora aas/bna to stoa. Th* maid* shadow uauadly lu a sharpty dadood baedx aad dawhar* fadoa toa th* aunaaOtog nft turn**. A sUghdy ohtipa* paymtoa wfl afta raaet** thto <HaaH protoae A piaspi* that to wol dadaod to pill baaaaa O dtftaad wha _routad to a oa fm* poafctoa. Addittoaai piagoa art ofta mm m th* rotatad thou Plapaa may baaaaa man dkttoct aa rotattoo me**a th* arartytog mud* ikadowt. oharau mto* ihidawt wfl altar thtor shap* or diaap* par. naaaal thirtwring ihooid at b* oeoAssad with aacapiaarai dapasiu of fat. Th* obUpa# ri*w ia agria kalpfei. th* fu prodhdeg a wary margia not prosahsaat aa th* poitoiatni strife* of th* riba, oaaady sparing th* attrior tad partv*n*hraJ ums." Tomography say bt JT m ktopM to rtrtaitog fat dadty to antrut a th* w*ur datoty af piaoni thfcfcaatoy. Cktplfe Hmni ft, Flaral ratdflcasto* aaaafly mean 20 yaata amrarabw* atgaaaratoitijiata*. iaaat*i i mi* th* taa* aumi." Th* at har* w b* pritoagidt it aa h* a th* ordor *f ooiy a fw wmka x maathSi dapadhtg m th* eoaaatrv ttoa f th* date Kaw**r. eaidfleactoo ia piarai piapua ia a rPaartoy oaeosamo* rv dtograptto toting. It ta mh amra eoouaoa biiMiagicaUy. oootrrtog to tppratoaatby STto of piapva.* Radiographically daaoattraai* rridaca of towntdat pmmoaaw aaaaa* am boa ttoonad to oaiy oao-thad afpatiattwuh blaraf piapao taiodcattoa. bat warwsmr mor* thaa 30% af panata with wtttasrr* DOF 0934611 036937 luHlul K t* usaorr. uasmnn. tm scxccxxcm aaiaeBtrr fibroca tvtamtiiy tad bb vith piturti catadcaacaa.'* At a ruit. caio&ad pltoaaa art sort abriotti tad mort itrian taaa uaaaicdltd pdaquat tut raantganofraa. Wb tit J-cty baa itritt t piaqnt atrpa uaftnuaJly, toa caito* Scaaoo to lit pUqs' H um u * dasit att itoa, uoatty Mam. dtoaotusaMi. porafladtot toa tktaa vail. 4ii*anm. or cardiac bordtr. San toa eaidsa ia dapslitMi saw tot eaatar at tot typiaai atboianrai kyaUatoad pdaqat- it ii aaparttad Son toa tooar mritn o( toa rib by a Um at *vm daatoty protoaead by tit nrTotadfet piaorto toitkmiat. Tit eaideatfeaa art atom aauil ad (tapaaiaily ia Sat at lav aaatnst) ad; overtookad ualtaa tyv iMattoaiiy mffet tftar fKja. 3 aad 7% Tkty art rart a lia tpptt aoata. If tic r*fvy boas saxfeai toa tarfoaa at a catafiad piaoua.at /art. k prttiau as irrvfoiar tad aaavdy daaaa potato. ipa tfua Gkaaad to tit Bfa at a body Itad or at*. Okfiqaa viavt art octraaady itoprtd to dataotof caieAeatim toot nay ia anoifattad to tot PA pro. jacOao. to rdnatog m /at* tOttotirlnti by *--rm toM tow patio. to mHTto| taltofl-- ttou to too rtfioto at tot toapkncaatto pianra or tot patfaardkim. ad to attodfef tottai cardUpt tUdlaarbw % Wka taiatfad pdaqna art anal r too toty art fir**TT'l`*J a tot rtoatoa doatr {tot ft Intones, ton partkaiariy via tot fitoi It tndMonwMd tr party pettaad. toty trt ofta tvortoaktd. Tkty art vtol tta an grid Sou. Uatikt tot aaUM pdaqaa. tot caitoStd pioott toy bt itetar tuUatd and its* to* taltoad by taatynfky. Pituatoorax bu iMinaniirt toat tot oittttd piaqaa to to tot partoui pdanra aad to oat ataotiaud vnk too* carai piaani totoivaMn. Tka tocatoM af toaa pioqaaa to toa paxiatai piaara sa ila ba cooSraad dnrtof Ufa by towiwep tr tonf diaqrtpky, vdtoto rtrtoU toat n iMpirattoa tot luat oova iadqadatiy at tot pdaqa ta* piaqua mova lyndutaooiiy ito toa cian ML* OtTOINTUt. OUONCSS Tit rrt baadar pitartl dfattot at ubtasotto raolvM sio*ty aad say lava dfss of rtetouai difftat pitorad thick aint. particniarty to tot aatioptratoa aflat. Plaorad pdao*** <*1 *ko DUt 0934612 DU 036938 i: .araiiiM i ejIiI-aaMBsSiiii KJUAM. RMUB \r * 00* 0934613 DU 036939 r 3apailB|H"t gte^akirtiiteiteainigintertBIteitellMrtnrtfrte*--______ J *UU*Aa. KMM ' Mp *t aaa-naaateaal nkanaa lammUr-MMcm*. A *rtM (SartU IJMU) 1*4:1-47, .M9 10. UtM lb Hate plaaan art aartaw: Fin otMratiMi tft ft^flMft tt4 Mtaf MWMMtQmi Ift* M* AM KY Anrt M IJ20I1-23*. IM 11. Ltak L CmikmM 'Harmr mmt 1*4 IMJ. (nteparaananuw. til Kite 300-14. 1777 12. laapnrt JH. Watea VFM. Tiapan MJ: UaaU4n nrtan Ikfart. Sunday at an nil at net Ir 1 u M*<aoi%af. mi 11 la Intel U Marti X. Oarlf S. at Soaaara art mmMm H Hate tete li|< *1 *. Olaat JC Ttaarti V ate (Mai M*aM Iteu af Aaaaraa. hamalap a/ a Wartlao CWuaaaa. liuarmiraM A|<Hy Ikr Uam n Canar (tTTJi lyao. iFraai UC Tnnla Hanmaw L im. n 2a*21T I*. 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