Document LgaEp9ngKmzL5GMEppBg4kn4X

MATERIAL SAFETY DATA SHEET Sigma-Aldrich Corporation 1001 West Saint Paul Ave, Milwaukee, WI 53233 USA V -;ion January 1992 For Emergency Contact USA/Canada Outside USA/Canada Sigma 800-325-5832 314-771-5765 Aldrich 800-231-8327 414-273-3850 PRODUCT #: 17105-0 NAME: HEXACHLOROBENZENE, 99% CAS #: 118-74-1 MF: C6CL6 SYNONYMS AMATIN * ANTICARIE * BUNT-CURE * BUNT-NO-MORE * CEKU C.B. * CO-OP HEXA * ESACLOROBENZENE (ITALIAN) * GRANOX NM * HCB * HEXA C.B. * HEXACHLORBENZOL (GERMAN) * HEXACHLOROBENZENE * HEXACHLOROBENZENE (DOT) * JULIN' S CARBON CHLORIDE * NO BUNT * NO BUNT 40 * NO BUNT 80 * NO BUNT LIQUID * PENTACHLOROPHENYL CHLORIDE * PERCHLOROBENZENE * PHENYL PERCHLORYL * SANOCIDE * SMUT-GO * RCRA WASTE NUMBER U127.* SAATBEIZFUNGIZID (GERMAN) * SANOCID * SNIECIOTOX * UN 2729 (DOT) * ------------------------------------- TOXICITY HAZARDS ---------------------------------------- RTECS NO: DA2975000 BENZENE, HEXACHLORO- TOXICITY DATA UNR-MAN LDLO:220 MG/KG 85DCAI 2,73,70 ORL-RAT LD50:10 GM/KG FMCHA2 -,C156,89 IHL-RAT LC50:3600 MG/M3 85GMAT -,72,82 ORL-MUS LD50:4 GM/KG 85GMAT -,72,82 IHL-MUS LC50:4 GM/M3 85GMAT -,72,82 SCU-MUS LD50:>10 GM/KG SRTCAC 36(1-4),10 DO A O?197 F CONF TDFNT T Al ORL-CAT LD50:1700 MG/KG 85GMAT -,72,82 IHL-CAT LC50:1600 MG/M3 85GMAT -,72,82 ORL-RBT LD50:2600 MG/KG 85GMAT -,72,82 IHL-RBT LC50:1800 MG/M3 85GMAT -,72,82 ORL-GPG LD50:>3 GM/KG PEMNDP 8,459,87 ORL-MAM LD50:1047 MG/KG NTIS** PB288-416 REVIEWS, STANDARDS, AND REGULATIONS IARC CANCER REVIEW:ANIMAL SUFFICIENT EVIDENCE IMEMDT 20,155,79 IARC CANCER REVIEW:HUMAN INADEQUATE EVIDENCE IMSUDL 7,219,87 IARC CANCER REVIEW:GROUP 2B IMSUDL 7,219,87 NOES 1983: HZD A1753000; TNF 2; NIS 10; NOS 12; TNE 1038; TFE 26 EPA GENETOX PROGRAM 1988, POSITIVE: CARCINOGENICITY-MOUSE/RAT EPA GENETOX PROGRAM 1988, NEGATIVE: RODENT DOMINANT LETHAL EPA TSCA CHEMICAL INVENTORY, JUNE 1990 ON EPA IRIS DATABASE EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, MARCH 1991 NTP FIFTH ANNUAL REPORT ON CARCINOGENS, 1989 : ANTICIPATED TO BE CARCINOGEN TARGET ORGAN DATA BEHAVIORAL (SOMNOLENCE) LIVER (TUMORS) ENDOCRINE (THYROID TUMORS) SPECIFIC DEVELOPMENTAL ABNORMALITIES. (CRANIOFACIAL) SPECIFIC DEVELOPMENTAL ABNORMALITIES (MUSCULOSKELETAL SYSTEM) SPECIFIC DEVELOPMENTAL ABNORMALITIES (UROGENITAL SYSTEM) EFFECTS ON NEWBORN (LIVE BIRTH INDEX) EFFECTS ON NEWBORN (VIABILITY INDEX) EFFECTS ON NEWBORN (WEANING OR LACTATION INDEX) EFFECTS ON NEWBORN (GROWTH STATISTICS) EFFECTS ON NEWBORN (BIOCHEMICAL AND METABOLIC) TUMORIGENIC (CARCINOGENIC BY RTECS CRITERIA) TUMORIGENIC (NEOPLASTIC BY RTECS CRITERIA) BIOCHEMICAL EFFECTS (PORPHYRIN INCLUDING BILE PIGMENTS) ONLY SELECTED REGISTRY OF TOXIC EFFECTS OF CHEMICAL SUBSTANCES (RTECS) DATA IS PRESENTED HERE. SEE ACTUAL ENTRY IN RTECS FOR COMPLETE INFORMATION. ------------------------------------- HEALTH HAZARD DATA ------------------------------------ ACUTE EFFECTS HARMFUL IF SWALLOWED, INHALED, OR ABSORBED THROUGH SKIN. CAUSES EYE AND SKIN IRRITATION. MATERIAL IS IRRITATING TO MUCOUS MEMBRANES AND UPPER RESPIRATORY TRACT. CAUSES PHOTOSENSITIVITY. EXPOSURE TO LIGHT CAN RESULT IN ALLERGIC REACTIONS RESULTING IN DERMATOLOGIC LEISONS, WHICH CAN VARY FROM SUNBURNLIKE RESPONSES TO EDEMATOUS, VESICULATED LESIONS OR BULLAE. CHRONIC EFFECTS CARCINOGEN. MAY ALTER GENETIC MATERIAL. TARGET ORGAN(S): LIVER FIRST AID IN CASE OF CONTACT, IMMEDIATELY FLUSH EYES OR SKIN WITH COPIOUS AMOUNTS OF WATER FOR AT LEAST 15 MINUTES WHILE REMOVING CONTAMINATED CLOTHING AND SHOES. IF INHALED, REMOVE TO FRESH AIR. IF NOT BREATHING GIVE ARTIFICIAL RESPIRATION. IF BREATHING IS DIFFICULT, GIVE OXYGEN. IF SWALLOWED, WASH OUT MOUTH WITH WATER PROVIDED PERSON IS CONSCIOUS. { DO A 07197A CONF T DF NT T Al CALL A PHYSICIAN. DISCARD CONTAMINATED CLOTHING AND SHOES. ------------------------------------------ PHYSICAL DATA -----------------------------------------BOILING PT: 323 C TO 326 C MELTING PT: 227 C TO 229 C AF \RANCE AND ODOR WHITE POWDER ------------------------- FIRE and EXPLOSION HAZARD DATA ----------------------EXTINGUISHING MEDIA WATER SPRAY. CARBON DIOXIDE, DRY CHEMICAL POWDER OR APPROPRIATE FOAM. SPECIAL FIREFIGHTING PROCEDURES WEAR SELF-CONTAINED BREATHING APPARATUS AND PROTECTIVE CLOTHING TO PREVENT CONTACT WITH SKIN AND EYES. UNUSUAL FIRE AND EXPLOSIONS HAZARDS EMITS TOXIC FUMES UNDER FIRE CONDITIONS. ---------------------------------------- REACTIVITY DATA ---------------------------------------INCOMPATIBILITIES STRONG OXIDIZING AGENTS HAZARDOUS COMBUSTION OR DECOMPOSITION PRODUCTS TOXIC FUMES OF: CARBON MONOXIDE, CARBON DIOXIDE HYDROGEN CHLORIDE GAS ------------------ ------------ SPILL OR LEAK PROCEDURES ----------------------------STEPS TO BE TAKEN IF MATERIAL IS RELEASED OR SPILLED EVACUATE AREA. WEAR SELF-CONTAINED BREATHING APPARATUS, RUBBER BOOTS AND HEAVY RUBBER GLOVES. WEAR DISPOSABLE COVERALLS AND DISCARD THEM AFTER USE. SWEEP UP, PLACE IN A BAG AND HOLD FOR WASTE DISPOSAL. VENTILATE AREA AND WASH SPILL SITE AFTER MATERIAL PICKUP IS COMPLETE. W. E DISPOSAL METHOD DISSOLVE OR MIX THE MATERIAL WITH A COMBUSTIBLE SOLVENT AND BURN IN A CHEMICAL INCINERATOR EQUIPPED WITH AN AFTERBURNER AND SCRUBBER. OBSERVE ALL FEDERAL, STATE, AND LOCAL LAWS. ------ PRECAUTIONS TO BE TAKEN IN HANDLING AND STORAGE -----WEAR APPROPRIATE NIOSH/MSHA-APPROVED RESPIRATOR, CHEMICAL-RESISTANT GLOVES, SAFETY GOGGLES, OTHER PROTECTIVE CLOTHING. SAFETY SHOWER AND EYE BATH. USE ONLY IN A CHEMICAL FUME HOOD. DO NOT BREATHE DUST. AVOID ALL CONTACT. WASH THOROUGHLY AFTER HANDLING. CARCINOGEN. IRRITANT. PHOTOSENSITIZER. MUTAGEN. HARMFUL SOLID. KEEP TIGHTLY CLOSED. STORE IN A COOL DRY PLACE. REGULATORY INFORMATION THIS PRODUCT IS SUBJECT TO SARA SECTION 313 REPORTING REQUIREMENTS. THE ABOVE INFORMATION IS BELIEVED TO BE CORRECT BUT DOES NOT PURPORT TO BE ALL INCLUSIVE AND SHALL BE USED ONLY AS A GUIDE. SIGMA ALDRICH SHALL NOT BE HELD LIABLE FOR ANY DAMAGE RESULTING FROM HANDLING. OR FROM CONTACT WITH THE ABOVE PRODUCT. SEE REVERSE SIDE OF INVOICE OR PACKING SLIP FOR ADDITIONAL DO A 071977 OONF TDFNT TA!