Document LgL2QON56vd7E3mmepyNZE5Rb

%gr;- -^WrPRrjfc-K- Pt.G'-rEWK-- Th* c*rdl*c p*tlnt in industry i. the topic of Ab.t. No. 123. ; Experiences with phase microscopy are described in Abet. No. 156. ^ roradtscussion on the verrucous carciaoaia of the buccal mucosa intobac' !0 clwor* con,ulk Abst* N* 13Q*... . ~2k ^valuation concerning the efficiency la- presented" to Abet ' Abst. No. 163 presents ceruminosis, a factor in audiometry. Information on food preservation by ionising radiation is giveit in Aba*.- No. 26th ANNUAL, MEETING OCTOBER 25 - 26, 1961 Industrial Hygiene Digest material and in making similar determinations on air samples. The major difficulties ex perienced lie in the need for delicate microscope adjustments and m the preparation of micro scopic samples from air samples collected m isopropyl alcohol. -- Author's conclusions 157 Silicosis of the Bone Marrow. J. L. Nicod and D. Gardiol. Arch. Gewerbepathol. Gewerbehyg. j_8, 70-90 (I960). French. Silica dust in the lung produces lesionB which always start as an accumulation of histiocytes round little blood vessels. Some particles are carried via the reticuloendothelial system, to other organs, and such particles retain their pathogenicity. The presence of sili cotic nodules in the liver and spleen is a common finding in the silicosis of miners and indus trial workers in Switzerland, but the presence of silicotic changes in the bone marrow has not so far been clearly demonstrated. The authors think that the reason for this is that the mor phological study has not been sufficiently complete. They have therefore examined the verte bral and femoral bone marrow from all silicotic cases examined post-mortem over a period of years, and have traced the progress of lesions caused by silica. The first reaction is an accumulation of histiocytes, at first fluffy, then more discrete. Silver staining shows up a close meshed network of fibers. Although such lesions become more sharply defined they for the moat part do not progress further. At this stage they are indistinguishable from those produced by infections such as tuberculosis. That is why they have been ignored by others interested in silicosis. It is concluded that the presence of silicotic nodules in the bone marrow shows that silica retains its toxicity even when it leaves the lung. Silicotic lesions should therefore be found in still more organs. Finally, a morphological study does not give any lead as regards functional damage. -- Cond, from Bull, Hyg. 158 Serum Lipoprotein and Protein Content in Silicosis. H. Valentin, N. Lichius and G. Zerlett. Arch. Gewerbepathol. Gewerbehyg, _1_7, 227-237 (1959). German. The authors made a detailed study of the serum protein and serum lipoprotein el ectrophoretic patterns of 56 silicotic patients. The results confirmed those of previous workers in that serum albumin was in the main decreased whereas gamma-globulin was in creased; lipoid fraction I levels were on the whole lower than those found in healthy subjects. There was no relation of serum lipoprotein content to grade of severity of silicosis. - - Bull. Hyg. 159 The Varieties of Asbestos, their Study by Optical Methods and their Pathogenic Action. K. G, Schmidt. Staub 20, 173-180 (June 1, 1960). German. Asbestos is usually classified rather unscientifically by the characteristics which make it technically useful, by its place of origin, its color and so on. With modern methods, however, including an elaborate microscopical technique, 11 well-defined varieties of as bestos can be distinguished, the most important of which are chrysolite, amosite, crocidolite, tremolite and anthophyllite. In discussing the pathogenic action, the author states that as bestos may possibly undergo changes in the lung. However, it is doubtful how far the different varieties can be recognized in the'lung dust. In speaking of the formation of asbestos bodies as a reaction intended to get rid of asbestos in the lung, he suggests that varieties susceptible to chemicals will form these readily. Chrysolite and possibly amosite may do so rather than the kinds of asbestos which are very resistant. Warning is given that the formation of bodies is not necessarily a disease. A considerable controversy has raged over the question as to whether chrysolite or hornblend is capable of producing bodies in the lungs. The literature as regards this and also the question of the action of short-fibered asbestos is reviewed. All forms of asbestos must be regarded as dangerous. It is suggested that chrysolite, crocido lite, and amosite have long, yielding fibers which can penetrate the lung more easily than the stiff brittle fibers of tramolite and anthophyllite. This would produce mechanical damage! chemical effects might result from the more sensitive chrysolite and amosite. The iron and aluminum content of the different types may also influence the pathogenic action. -- Cond. from Bull. Hyg 16. h.i t. , 'A^ (, '* ,vn' . >>} ,* ^mN-irnw' ?"' 'J" - - ' - -' t ''. I, ,, M 7; , .' -' ' *'` 1 Industrial, Hygiene New smoke and air pollution control rules and regulations are enacted by Allegheny County. See Abst. No. 728. The effect of smoking on asthma and emphysema is discussed in Abst. No. 734. ? Abst. No. 735 presents information on tobacco' amblyopia. Abst. Nov 740 is concerned with, edu cation for industrial medical practice. Dermatoses from phenylmercuric salts is the subject of Abst. No. 742. See Abst. No, 746 for information on the present status of skin tests. The topic of Abst. No. 756 is the role of roasted chromite ore in the produc tion of cancer; Mercury as a potential hazard in medi cal laboratories is considered in Abst. No. 758. Pathological changes in ethylene dibro mide poisoning is the objective of Abst. No. 763. Data on the myocological contamination of impinger samples are given in Abst. No. 769. Consult Abst. No. 772 for mammal tical aspects of dust counthic.r, ' A case report on asbestosl*^ ' * cinoma bf the luhg iS^ 7oI. ---_tSV' tfTJlJjjJj For * discuss absorption in 787.." Microwave radiation fiasi cussed in Abst. Nfci Man versus environm of Abst. No. 808* Adhesion of solid particles^ faces is the title of Absi. ------- - ^ . A discussion on automation ployment is presented in Abst. OUNDA TION `ACTS * - * ' HE/*' '* ' .__ ,.;r' : A , M . A . ARCHIVES OF INDUSTRIAL HEALTH has changed its name to Archives of Environmental Health beginning with the July 1960 issue, and will start with Volume 1, Number I. DR. GROSS PRESENTS PAPER AT INTERNATIONAL CONGRESS. Dr. Paul Gross, ' the Foundation's Research Pathologist presented a paper on "The Synergistic Action of Tuberculin with Quartz Dust" on July 28 at the 13th International Congress on Occupational Health, held In New York City. SILVER ANNIVERSARY MEETING OCTOBER 26 27, 1960 "7 Thu Bronchoscopic Picture in a..icotune re u.: s; s. A. Ferraris ar.d G. Paoii. Lotti i-jr.trv toborc. u_p . Lid . - .' .oO (July-Aug. 1959). Italian. In this paper the autr.ors give 3 scnematic outlines to show what are the likely, sometimes alternative, details which mav be seen through the bronchoscope in cases of silicosis, broncho-pulmonary tuberculosis and silicotuberculosis respectively. The tracheo bronchial lesions which may be found to affect the picture seen in respiratory tuberculosis also schematically listed according to 2 separate authorities. It is obvious that the many lesions may combine in a wide variety of patterns in each of the 3 diseases and so may the signs to be seen throughout the bronchoscope. No pattern or patterns can be expected to be typical of silicotuberculosis, but a bronchoscopic examination can, nevertheless, prove of great value in the diagnosis of this condition and this is illustrated by a series of 6 cases, -- Cond. from Bull. Hyg, 7 80 The Bronchographic Picture in Silicotuberculosis. A. Ferraris and G, Paoli. Lotta contro tuberc. 29, 1031-1050 (July-Aug. 1959). Italian. In their paper on bronchoscopy (see previous abstract) the authors set out 3 schematic outlines of the likely bronchographic signs, to be seen in cases of silicosis, broncho-pulmonary tuberculosis and silicotuberculosis respectively. From another authority they quote a list of the signs which may be observed when tuberculosis involves the bron chial system. The signs will combine in manydifferent ways to give a wide variety of bron chographic shadow patterns none of which can be said to be typical of silicotuberculosis, but bronchography can still be of great value in diagnosis. The authors carried out both broncho- scopic and bronchographic examinations on 27 patients found to be suffering from silicotuberc ulosis and they select 6 of these to describe their findings and conclusions in each case, re producing photography of the bronchography and of the chest radiography. Both bronchoscopic and bronchographic pictures m one of these cases showed the signs of silicosis but did not show evidence of the associated tuberculosis at the time. In two other cases, both broncho scopy and bronchography gave indications of the tuberculous association, while in 2 other cases the indications were seen by bronchoscopy but not by bronchography and in the other case it was the opposite. -- Bull. Hyg. ~-1 Asbestosis and Carcinoma of the Lung, Case Report and Review of the Literature. J. Anderson and F, A. Campagna. Arch. Environmental Health 1, 27-32 ( July I960). A case ol asbestosis associated with carcinoma of the lung is presented. The literature is reviewed, and this is the 24th reported case, with complete autopsy findings. In general, it conforms to the previously described cases where a relationship between the 2 diseases is intimated. It is suggested that further cases of asbestosis, with and without neopiasia, be reported with careful attention to other factors, such as smoking. Only when these facts are available will final assessment of the relationship between asbestosis and lung carcinoma be possible. -- Authors' summary "^2 Pneumoconiosis (Taicosis) in Soapstone Workers. A, Ahlmark, T. Bruce and A Nystrom. Nord. Med. 59, 2.37-2sd (Nov. 20, 1958). Mining ana pr ocussing o: soapstone in Sweden are confined to 2 places and employ oniy abw.it 1 L-f men. TV. e stone consists mainly of the minerals talc and chlonie. The dis Cd.iV condition p r.iCuc ed hy exposure to such dust is best described as taicosis. The authors ut iC ntjc 5 Cjsvh k>! II.l.C iii.eumoconiosis which were demonstrated after at least 2'.' years ~ X j/O s w. > t* :\*;c alter mure char. 30 yearn exposure. In no ci-.-e was the working k ,i]ju . led. -- APGA Ab = t-