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Hie Government Chemist, Hie Government Laboratory, Cornwall House, Stanford Street, LONDON, S.E.l.
20th February, 1967
Dear Sir,
We are currently Interested in organochlorine residues in animals and birds, and have noted a reference to the work of Simmons and Tatton of your laboratory, Hiey are stated to have examined human gall stonea and found euoh residues in 26 patients from two hospitals.
I would be glad to have any furttier information that is available concerning these experiments and on any similar work you may have carried out in the videffield of our interest.
Tours faithfully.
D.Y.N. HARDY
EXHIBIT
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EXHIBIT WBPM-76
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Monsanto EUROPE ft.A
SUBJECT
:
REFERENCE :
TO :
Belgium, 27th February, 1967
DWsgb D. V. N. Hardy - London
cc
I should like to confirm our telephone conversation of last week, when I requested that you send small samples of the various isomers of Aroclor to Mr. Soren Jensen
Institute of Analytical Chemistry, University of Stockholm, Stockholm, 50, SWEDEN.
Apparently samples of about 10 mra/grams each would be sufficient for Mr. Jensen's need and he was particularly interested in the lower chlorinated and more highly chlorinated biphenyls.
Wood.
EXHIBIT WBP M-76.1
MON-MT-008561
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LEXOLDMON000605
u.v.M. naxuy, umdon }rd Maroh, 1967
JfonUflPftte-SQ-gl Ormnochlorine Residues dvnm/arv
J.C, Hawkoa, Rusbon
D. Wood, Brussels
You reoently supplied me with mall Maples (10 agroe. or so) of eubutantially pure Arcelor ooaponents for transmission to Mr. A. hiol.ardson, of Shall Chmloals. Ba now says that non* of these substances Is similar to the unidentified organoohlorine reslduee which are eery widely spread e.g. in aea birds. Ihe Government laboratory Is also ooncemed with this general problea and have found that there is sons correlation with a saaple of Aroclor Basin (no other distinguishing sorts on the label!). As you will know the interest in this problea derives froa the work of Jensen end a soaxeeongering article in the Swedish press in whioh a highly ohlorinated biphenyl was indlo ted.
To help the three sets of workers and, at the sane time, do all we oan to dear Aroolors 1 would like further sots of the eanpies aa supplied to Richardson to go toi-
Mr. Soren Jonsen, Institute of Analytloal Chemistry, University of Stookhola, Stockholm 90, Sweden. and Mr. J.O'G. Tatton, Laboratory of the Government Chemist, Cornwall House, Stamford Street, London, 5.K.I.
Additionally Z would like to lnolude small samples of Aroolors 9460 and 4469 with eaoh of the two seta, and to hava similar snail samples of these Aroclor resins to go toi-
Mr. A. Riohardson, Shell Chemicals, Tunstall laboratory) Sittingbourne, Kent.
In the oaee of the aanples for Jensen would you say that they are sent at the request of Mr. D. Wood of our M.B. Brussels Office. In the oaoe of the other samples would you indioate that they are sent at ay request.
EXHIBIT WBP M-76.2
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TUNSTALL LA BO RATO RY, BROAD OAK ROAD, SITTINGBOURNE. KENT.
9
6th November, 1967
Dr. V.N. Hardy. Monsanto Chemicals Ltd.,
Monsanto House, 10-18 Victoria Street, London, S.W.1.
Dear Dr. Hardy,
I thank you for your letter of 3rd November, I9&7, which indicates that we nro both concerned with tbo-very similar problems,
I suggested that there was possible contamination of the river Witham because of the occurrence of the P.C.B's in the eggs of herons feeding on fish which come from the Witham Catchment area. More specifically the heronry is at Tunby Woodside, Lines., some 10 miles from Boston. I suggest that water pollution may be responsible because the P.C.B's appear to occur to their largest extent in birds from an aquatic environment. We have no evidence of P.C.B. content in herons from elsewhere but we do find that some sea birds from the N.E. Const also contain P.C.B's whilst on the N.W, and West Coast of Scotland they are absent.
In answer to your second point I would guess that there are several areas of pollution and the Scandinavian source is different from our own. I .believe that the fact that the human in the United Kingdom contains very little would indicate that the source of pollution is of aquatic origin. If the atmosphere were polluted to any extent human fat would contain these compounds and from our own experience if they are present it is at very low concentrations indeed, possibly less than 0.1 ppm.
To answer your third point, particular chlorinated insecticides and/or their metabolites occur in almost every organism in the United Kingdom. The biphenyls are not so widely distributed, but like the chlorinated insect icicles DDT and its metabolite DDE, and Dieldrin they reach their highest concentration in some aquatic birds where thay may occur in equal or greater concentration than do the insecticides, I would say that the maximum concentration of P.C.8'5 that we find in wildlife is of the order of 10 to 20 ppm.
, " EXHIBIT
-v It is very difficult to assess the hazard of the P.C.B's but from the I Tirol) lV/f A concent rat ions that we find and the reported LD it is unlikely that the WrJr M-/0.4 residues of P.C.B. constitute a direct toxic hazard.
If it would be of any assistance for you to come and discuss this problem with us we would be very glad to see you.
Yours sincerely,
A o j..
MONS 086U5
LEXOLDMONOOO6O8