Document LKkrpBxLR6zeb0QOng4LXr0p3

*A. i BAXEUTC COMPANY A DIVISION OF UNION CARRIPC CanSON CORPORATION .;> ' - -r -. f A a <a `-'fc A/Dr Carl tl* Dernehl-Roam 203300 Madison Janoaiy 27, 1956 Dr. Jeron Klalmrnan Department of Medical Reaaaroh Saint Lake*a Hospital 113U Shaker Boulevard Cleveland k$ Ohio sear or* Kmnanatu . At tte ioat af Br. Bamehl, Aeaietant Medical Slreotco of oar Induetrial Medical and Toxtoologr Department, m are sanding yea without Charge five pooode of VIKILHE retin TTHB #1* this towin la oral 1 able in coanaralal quntltiN and ST be ordnrad trm the Bake11te Ocnpany, F, 0, Box JlA, See Tort 8, V* 1* UCC 063363 RECEIVED JAN 30 1956 INDUSTRIAL MEDICAL & TOXICOLOGY DEPARTMENT Saint Luke's Hospital OF THE METHODIST CHURCH 11311 Shaker Doulevard Cleveland 4, Ohio January 17, 1956 Dr. C. U. Dernahl, Assistant Medical Director Union Carbide and Carbon Corporation 30 East Forty-Second Street New York 17, New York Dear Dr. Dernehl: Thank you for your letter of January 12. We anticipate using "Vinylite"resin for injection studies of lungs in various experimental and clinical conditions. These procedures have been described by Dr. A, A. Diebow of the Department of Pathology at Yale University, We are now in the preparatory stages of this investigation, and we are not able to adequately foresee our ultimate needs for this compound. However, if you could furnish us with several pounds of this material, we would certainly be able to work out our methods. If it is not possible for you to furnish us with this compound, we of course would be very happy to reimburse you. We are extremely eager to start our work and would appreciate your prompt attention in this matter. Sincerely yours. I..A-Q JKraer Jerome Kleinerman, M. D. Dept, of Medical Research RECEIVED INCU miaiCAl l TOXICOiOC i' DEPARTMENT ucc 063369 January 12, 1956 Dr. Jerome Klalnarman Dept, of Medical Research Saint Luke's Hospital 11311 Shaker Boulevard Cleveland 4, Ohio Dear Dr. Klelnemant Xn reply to your letter of January 6, 1956 to our Bake11te Company regarding Information about "Vinylite" resin VTHH Speelfleatlon 1, X oan give you the following data. This material la a copolymer of vinyl ehlorlde and vinyl acetate with the vinyl chloride being present slightly In excess of 80 per cent. Xt la old as a fine flour without added stabilisers or plasticisers*- Xt would be helpful to us to know the proposed application for this material. If It is Intended to convert the flour Into film for use on humans, your attention should be dlreoted to a recent publicationt *Further Studies of Polymers as Carcinogenic Agents In Animals," B. 3. Oppenhelmer, CANCER RESEARCH, 15*333-340, June, 1955. Vhlle this paper demonstrates the development of malignancies after film Implantation In animals, this Is no proof that similar responses will occur In man. Even though such responses have not been observed In husana, the possibility must be considered. Otherwise the resin Is ^considered to be physiologically Inert. -V ,, ^ Xf the quantity of material desired Is not large and the application Is suitable, X feel sure that a supply an be made available without charge. Information on the proposed use will expedite action on our part. , *' cry truly yours. 0. Dernehl, I. D. A83X8TAHT MEDICAL DIRECTOR ucc 063370 Saint Luke's Hospital or THE METHODIST CHURCH 11311 Shaker Boulevard Cleveland 4, Ohio January 6, 1956 Union Carbon and Carbide Chemical Corporation Bakelite Division 437 MacCorkle Avenue South Charleston, West Virginia Gentlemen: We are interested in your product, VINYLITE, (VYHH, Specification #1) for purposes of Medical Research. Information as regards composition, cost, delivery dates, and other pertinent information will be greatly appreciated. hfey we hear from you soon? Sincerely yours. JK:ar Jerome Kleinerznan, M. D. Dept, of Medical Research RECEIVED JAN 11 nr INDUSTRIAL MEDICAL & TOXICOLOGY DEPARTMENT ucc 063371