Document LK0EbJy9zpEBw9w9Dx0dGKeKd

TELEPHONE HUDSON 3-6126 Manufacturing Chemists' Association, Inc (FOUNDED 1872) 1825 Connecticut Avenue, N. W. Washington, D C. 20009 October 19, 1965 To: FOOD, DRUG, AND COSMETIC C Subject: Committee Meetii Gentlemen With only one member of the Committee reporting a conflict on November 17, Chairman Hagan directed that the next meeting be called for that day, as you were tentatively advised several weeks ago. It will take place in the MCA Conference Room beginning promptly at 10 AM. A tentative agenda is attached. A highlight of the meeting will be a report by Dr. Spencer on the third meeting of the Codex Alimentarius Commis sion, currently in progress at Rome. Dr. Spencer is attending with the U. S. Delegation as an industry advisor on food additives. Very truly yours. GEB:tp Attachment cc: Mr. Lloyd Symington Mr. M. M. Hoover George r.. cesc ASI 00001541 Excerpt - Draft Report of Third Session,, Codex Alimentarius Commission, Rome, October 19-29, 1965 CODEX COMMITTEE ON FOOD ADDITIVES 13. The Commission, having further considered the membership and main responsibilities of the Codex Committee on Food Additives and the Joint FAO/WHO Expert Committee on Food Additives set out in paragraph 22 of the report of its second session, decided to modify the procedure set out in paragraph 23 of that report and to recommend the following in Its place: (a) The Codex Committee on Food Additives should carry out a general review of the whole field of Food Additives and plan the work required to be done. Taking into account the lists prepared by Codex Committees and other international bodies of additives used in specific foods, the Codex Committee on Food Additives should evaluate the technological need for the use of the additives and prepare priorityTTIs^s". Priority*should be given to those food additives which are used in foods entering international trade in substantial amounts. Any government which wishes to suggest the Inclusion of any particular additive belonging to the group of additives under consideration by the Codex Committee on Food Additives in a Codex list of permitted additives should sub mit full information about the additive, including evidence of need, suggested level of use, to the Chairman of the Codex Committee on Food Additives, Ministry of Agriculture and Fisheries, The Hague,Netherlands. At the same time data on i) specifications of identity and purity should be sent to Science Branch, Nutrition Division, FAO Rome, and li) data on the toxicological and related properties to Nutrition Unit, WHQ Geneva. If the Codex Committee considers that a case has been established on the basis of need and that the additive concerned is not unsuitable for Inclusion in a permitted list, the Codex Committee will ask the Joint FAO/ WHO Expert Committee on Food Additives to consider the additive concerned. (b) The Joint FAO/WHO Expert Committee on Food Additives should, as expeditiously as possible, establish acceptable daily intakes and specifications of identity and purity for all additives so submitted. This data would be communicated to the Codex Committee on Food Additives. (c) The Codex Committee on Food Additives would then recommend levels of use for the food additive in specific foods and submit such levels of use to the Codex Alimentarius Commission. (d) The Codex Alimentarius Commission would invite government comments on these levels of use according to regular Codex procedure. 14. In addition, the Commission decided that the general principles for the use of food additives as prepared by the Codex Committee on Food Additives should be sent, amended in the light of the discussions, to governments for comments in accordance with Step 3 as set down by the Commission for the elaboration of standards. ASI 00001542 5 Excerpt - Draft Report of Third Session, Codex Alimentarius Commission, Rome, October 19-29> 19&5 PESTICIDE RESIDUES 23. The Commission received a brief oral report on arrangements being made for the first session of the Codex Committee on Pesticide Residues which is scheduled to be held in The Hague in January 1966. The Co mission was informed that it was hoped to make available the provisional agenda for this meeting early in November, The Commission, having noted that in future the WHO Expert Committee on Pesticide Residues will meet jointly with the FAO Working Party on Pesticide Residues (here after referred to as the Joint Meeting on Pest icide Residues) and having considered the membership and main functions of the FAO and WHO Committee working towards the establishment of tolerances for pesticide residues on an international basis as set out in Paragraph 38 of the report of its second session, decided to modify the procedure set out in paragraph 39 of the report and to re commend to adopt the following revised procedure: (a) The Codex Committee on Pesticide Residues should plan the work required to be done, taking into account the work al ready done by the various expert committees of the PAO and WHO, should prepare priority lists and transmit data to the Joint Meeting on Pesticide Residues, Priority should be given to those pesticides which are used in substantial amounts on food entering international trade. Any government which wishes to suggest that an international tolerance be established for a particular pesticide on specific food pro ducts should submit full information regarding technological justification, levels of residues resulting from their use, tolerances, consumption of food concerned, methods of analy sis for residues to the Codex Committee on Pesticide Residues, Ministry of Health, The Hague, Netherlands, with copies to the Plant Production and Protection Division, PAO, Rome. At the same time, two copies of all toxicological and related data should be sent to Nutrition/Pood Additive?, WHO, Geneva. If the Codex Committee considers that a case has been estab lished on the basis of need, that the pesticide concerned is not unsuitable for Inclusion in a Codex list and that adequate data have been provided, they will transmit the data to the Joint Meeting on Pesticide Residues for consideration. (b) The Joint Meeting on Pesticide Residues should, as expedit iously as possible, establish acceptable dally intakes, tol erances on specific foods based on good agriculture practice checked against the acceptable dally intake and methods of analysis. They should transmit their report to the Codex Committee on Pesticide Residues. (c) The Codex Committee on Pesticide Residues would then recommend, where necessary, tolerances for acceptance by governments for the pesticide in specific foods and submit such tolerances to the Codex Alimentarius Commission. ASI 00001543 2- (d) The Codex Alimentarius Commission would Invite government comments on these tolerances In the usual manner. 24. Under Rule IX.8 the Commission confirmed the continuing chairman ship of the Codex Committee on Pesticide Residues to be the responsi bility of the Government of the Netherlands. ASX 00001544 u/ A1/ "T? ^jt Aa/r FOOD AND AGRICULTURE ORGANIZATION OF THE UNITED NATIONS ORGANISATION DES NATIONS UNIES POUR L'ALIMENTATION ET L'AGRICULTURE ORGANIZACION DE LAS NACIONES UNIDAS PARA LA AGRICULTURA Y LA ALIMENTACION Rome, Viale delle Terme di Caracalla. Cables: FOODAGRI, Rome. Tel. 5797 WORLD HEALTH ORGANIZATION ORGANISATION MONDIALE DE LA SANTS Gendve, Palais des Nations. Cables: UNISANTE, Geneve. T6I. 33 10 00 ALINOBM 65/l2(l) August 19^5 JOINT FAG/WHO . EOGRAM ON FOOD STANDARDS CODEX ALIIiENTARIuS COMISSION Third Session, Rome 19-29 October, 1965 Progress Reporn of the joint FAQAjKO Expert Commits to on Food Additives < 'Xt'T 1/ ft-t "K w Afi A 1. The Joint PAO/WHO Expert Committee on Pood Additives met in Geneva 8-17 1)006111801 1964-. The Commit toe drew up specifications for identity and purity and made toxicological evaluations on a number of food colours. In addition, at tho request of the Codex Committee on Pood Additives, a number, of antimicrobials and antioxidants were re-evaluated. As specifications for identity and purity were not established for all antimicrobials and antioxidants considered in tho sixth report of this Joint Committee, the 1964 Committee also drew up such specifications. 2. The deliberations of this Committee arc given in the Eighth Report of the Joint FAO/WHO Expert Committee on Pood Additives which is published in WHO TRS (1965) 309 and PAO nutrition Mootings Report Series No. 38. Out of some 160 colours considered for only three was an acceptable daily intake established. The monographs on individual food colours will appear later in rotaprinted form under the title "Specifications for the Identity and Purity of Pood Additives and Their Toxicological Evaluations Pood Colours" and the revised monographs on some antimicrobials and antioxidants will appear under the title "Specifications for the Identity and Purity of Food Additives and their Toxicological Evaluation; Some Antimicrobials and Antioxidants". 3. It was necessary to start preparations for the December 1965 meeting of the Joint FAO/WHO Expert Committee on Pood Additives before the meeting of the Codex Committee on Pood Additives. Therefore, the list of substanoes to be considered at this mooting has been agreed upon by PAO and WHO. The list is given in Appendix 1. However, the Codex Committee on Pood Additives has recommended that the substances listed in Appendix 2 should be considered at the 1966 meeting of the Joint FAO/WHO Expert Committee on Pood Additives. 29680/3 ASI 00001545 ALIHORM 65/12(1) APPENDIX 1 Preservatives Diethyl pyrocarbonate Butyl p-hydroxybenzoate Sodium salts of butyl, ethyl, methyl, and propyl p-hydroxybenzoate Calcium and potassium benzoate Potassium metabisulfite Hydrogen peroxide Calcium, potassium and sodium sorbate Calcium disodium ethylenediamine-tetraacetate Disodium ethylenediamine-tetraacetate Propionic acid Hi trofurazone Sodium dithionite Antioxidants or Synergists Stearyl citrate Stearyl tartrate 2,4,5 Trihydroxybutyrophenone Bleaching and Maturing Agents Acetone peroxides Ammonium persulfate Azodicarbonamide Calcium uidate Calcium peroxide Calcium stearyl-2-lactylato Chlorine Monocalcium phosphate Oxides of nitrogen Potassium iodate Potassium persulfate 1 A.cids Acetic Adipic Fumaric Gluconic Hydrochloric Lactic Malic ASI 00001546 ALIKOEM 65/12(1) APPENDIX 1 pago 2 Base3 Ammonium hydroxide Calcium hydroxide Calcium oxide Carbonates and bicarbonates of. ammonium, Magnesium hydroxide Magnesium oxide Potassium hydroxide Sodium hydroxide magnesium, potassium and sodium Emulsifiers and Stabilisers Acetyl tartaric acid esters of uono- and diglyc^rides Brominated vegetable oils Ethyl cellulose Propylene glycol alginate Propylene glycol mono-palmitate Propylene glycol mono-stearate Tannic acid Eydroxypropyl methylcellulose \ ASI 00001547 $ AllNORM 65/12(1) APPENDIX 2 Suggested. Items for Consideration at 10th Session of Joint FAOATHO Expert Commit too on Food Additives (1966) by ' fie Codex Committee on Food Additives 0:. T / Emulsifiers. Stabilizers and Maturing agents Bleached lecithin Hydroxylated lecithin Propyleneglycolothcr of methyl cellulose Methylethyl cellulose Hydroxymethylcellulose Sodium celluloseglycolate Carboxymo thylgallactomanndn Carboxymethyl starch Modified starches Sucroesters and oucroglycorides Polyvinyl pyrrolidon Monostearin sodiumsulfoacetate Mannitol Taurocholic acid and Na-salt Furcelleran and its salts Cholic acid Desoxycholic acid Glycocholic acid Fatty acids and their calcium-, potassium-and sodium salts Ethyl-hydroxy-ethyl-celluloso Ester3 of polyglycorol and polyricinoleic acid Esters of polyglycorol and fatty acids Esters of polyglycerol and dimerized or polymerized fatty acids of soybean oil Esters of polyglycerol and oxidized soybean oil Esters of polysaccharides and fatty acids Mono-and diglyceride compounds of ( i) citric acid ( II; lactic acid (ill) phosphoric acid ( IV) acetic acid ( V) tartario acid Esters of fatty aloohols and hydroxy acids Dextran Carrageen and its salts (arabic, guar, karaya,' oat, tragacanth, carob beans, cornhulls, wheat, etc.) Gelatine Gums Pectin Amylopectin Gluten Casein and its salts Saponins AS1 00001548 Enzymes Miscellaneous Copper carbonate Ny&statin Nisin Formaldehyde Tetracycline ALINORM 65/l2(l) APPENDIX 2 page 2 ASI 00001549 FOOD AND AGRICULTURE ORGANIZATION OF THE UNITED NATIONS X /<S ORGANISATION DES NATIONS UNIES POUR L'ALIMENTATION ET L'AGRICULTURE ORGANIZACION DE LAS NACIONES UNIDAS PARA LA AGRICULTURA Y LA ALIMENTACION Rome, Viale delle Terme di Caracalla. Cables: FOODAGRI, Rome. Tel. 5797 LL * WORLD HEALTH ORGANIZATION ORGANISATION MONDIALE DE LA SANTE Gengve, Palais des Nations. Cables: UNISANTE, Geneve. T4I, 33 10 00 ALINORM 65/24(1) August 1965 JOIHT FAO/WHO PROGRAM OH FOOD STANDARDS CODEX ALIMEHTARIUS COMMISSIOH Third Session, Home 19-29 October, 1965 Progress Report of the Joint Meeting of the WHO Expert Committee on Pesticide Residues and the FAQ Committee on Pesticides in Agriculture and the FAQ Working Part.v on Pesticide Residues 1. During the Joint Meeting of the FAQ Committee on Pesticides in Agriculture and the WHO Expert Committee on Pesticide Residues, held in March 19^5? 37 compounds, previously considered, were re-evaluated, and an additional 15 compounds st\; ad. For 21 pesticides, the monographs remain as they appeared in WHO/Food Add./23 (1964) or FAO Meeting Report Ho. PL/l963/l3. For 11 substances (i.e. aldrin, dieldrin, endrin, heptachlor, dimethoate, malathion, parathion, carbaryl, captan, triphenyltin compounds and lead arsenate) new information was added to the monograph without affecting the evaluation of the hazard to man, A re-evaluation was made for chlordane, propham and ohlorpropham. nevertheless the infor mation about these compounds was still- insufficient to allow an acceptable daily intake for man to be established. The acceptable daily intake for DDT was raised and one for diazinon established. 2. Of the 15 compounds considered for the first time, all of which areextensively used on cereals, 1,0 were fumigants and 5 were other compounds. Of the fumigants, the acceptable daily intake was established for one (hydro gen cyanide), and an acceptable daily intake for total bromide was agreed upon, which enabled establishment of permissible levels and tolerances for the bromide resulting from the use of ethylene dihromide and methyl bromide, by the FAO Working Party on Pesticide Residues. Ho acceptable daily intakes'*' could be established for the five other compounds used extensively on cereals. 3. The report of this meeting will appear in ro*taprinted form and will only contain the main conclusions of the Committee. The toxicological and residue data to go with the toxicologioal evaluation will follow later in the same form in two separate documents, one entitled "Evaluation of the Toxicity of Pesticide Residues in Food" and the other "Evaluation of Hazards to consumers of Fumigat d Food". 29679 ASI 00001550 ALINORM 65/24(1) page 2 4. The FAO Working Party on Pesticide Residues which met in May of 1965 considered 14 compounds used extensively on cereals and for which acceptable daily intakes had been established. Of these 14 compounds, tolerances for 4 compounds, Ethylene dibromide, Methyl bromide, Malathion, and Hydrogen cyanide were recommended, together with appropriate methods of analysis. The documents resulting from this meeting are being sent out to the members of the Working Party for comments and it is expected that a preliminary English version of the report will be available for use by the Codex Com mittee on Pesticide Residues on a restricted basis. 5. It will be necessary to start preparations for the 1966 meeting of the WHO Expert Committee on Pesticide Residues and the FAO Committee on Pesticides in Agriculture before the meeting of the Codex Committee on Pesticide Residues. Therefore, the list of pesticides to be considered in 1966 will be agreed upon by FAO and WHO based on recommendations made to the two organizations by the FAO Working Party on Pesticide Residues. However, the next meeting of the Codex Committee on Pesticide Residues will recommend pesticides to be considered by the 1967 meeting of the Joint'Meeting' of the WHO Expert Committee' on Pesticide Residues and the FAO Committee on Pesti cides in Agriculture. I ASI onooikci