Document LJro8V2ZLv62R4K6M9gXMGYGg
PATHOLOGY SHEET
REQUESTED BY
DOW - TOXICOLOGY
CHARGE NUMBER
I JAN. IDENT* OR NUMBER
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materijCC and >oute of administration
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SEX
SPECIES
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PATH NUMBER
7
FILE NUMBER
tfer-/'-/7//-2?
SAVE Tissues
ROOM
RACK
Q YES NO
CAGE
DOSE OR CONCENTRATION
^ZXD-O^227-
DATE OP NECROPSY
7
MODE OF DEATH
MF DECAP
DATE TYPED AND CASSETTE NUMBER
11-8-79 G561Am
GROSS PATHOLOGY REPORT*
externally
There appears to he slight abdominal distension.
internally
NVL
KAV 7#J-
It is specifically noted that this animal did not have^iJw-^^*'^4' Qaj JLhw
THIS MOUSE WAS PRESENTED ALIVE AND KILLED BY DECAPITATION FOLLOWING METHOXYFLURANE AlfesiUESlA.
1C Ai Johnson, D.V.M., Ph.D.
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`Unless noted, no visible Lesions (NVL) were observed. For specific procedures followed during pathologic examinations refer to protocol and/or "Pathology Procedures Manual."
PATHOLOGtST/DATE
LIGHT MICROSCOPIC EXAMINATION REPORT*
PATHOLOGY NUMBER
Anitng1 WllBlW 7Q_ft,,n
3-4-SO MR4QBtii
5000 PPM DOSE LEVEL. FOUR (4) EXPOSURES. FIVE (5) DAYS RECOVERY. HEALTHY WHEN KILLED.
ILiver
rrhree sections) There is very slight enlargement of the centrilobular nepatocytes. "There are multifocal microscopic aggregates of RE-cells,
overall, this change is very slight.
Gallbladder
NVL
Kidneys
There is a focal accumulation of mononuclear inflammatory cells in the renal
cortex, overall, very slight.
Thymus
NVL
K. A. Johnson, D.V.M., Ph.D.
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PATHOLOGIST FORM C-32030 PRINTED R-12-76
*S0p foornntp on front
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(back)