Document LJDGJNgj4dKgoDjxO849N2YK5

- Sare GY SnLaUdrTrMyVeiRc.eesZroebsDeiilrd,eecnMttoDr MPH 3M Medica Department BEHR _ 10S- 00373 ces RECEIVED OPPYICBI 05HOV23 MMII:05 S351Mr7C5eln3te1S,81BEuiOfdfEiincge10020200-06-W.08 Gimsinin MH 270547 AR 226 - 3S55667 November 16, 2005 GEHQ -9P- 223 Re: TDoScCkAetSNeocst.io8nE8H(Qe)-1S1up8p0l-e3m7e3ntaanldSSuEbHmiOs-s1i1o8n0s:-374 No CBI Dear Sir/Madam: CaNTamsNO on f3lMuorhoacshpermeivciaoluss.lyAssuabmsiutptpeldeamneanltyttiocatlhoresseulstusbmfiosrssieornus,m 3meMaspurroveimdeenstsadodiftviaorniaolursesults as : described below. tThwrooufgehmtahleeirfplruiovraotcehpehmyisciaclipalnasntanwdorrkeeqruessptreodvtihdaetd33MMawniatlhyzseetrhuemssamapmlpelse.s fAorttohtealiorfchtihlrdreeen cahpiplrdorxeinmwateerleys8ammpolnetdh,s,onteentimmoenteahcsh.andTotwtoheybeeasrtsooff a3gMe'satunthdeertsitmaendoifnsga,mtphleincgh.ildArtenthweetrieme, tfhleuowroorckheermiscpaalrst.icTiphaitsedpriong3rMa'msdoocecsunpoattiionncalludmeedcihciladlresnu.rveTihlelasnacmepplrionggrwaamsfodroneat the requestofthe mothers. W`Tohrekmeorth#e1r'hsadbloonoed cwhailsdssaammpplleedd,ininthtehefaflalllofof1929080,0,anwdheangatihne icnh2i0ld00w,asseavebroault m1o0ntmhosntahfsteorld. ltehveeblasbayr'espbriorvthi,deads hpearrteotftohofeferregsuolmarelycosnctheextd,ulbeudt otchceuypdaotinoontalremporneisteonrtinigm.meTdhiuast,etphree-maternal pregnancy, gestational, or immediate post-partum levels. Worker # 2 has two children. Child A was also sampled in the fallof2000, at approximately age 2. The sample from 2000 was re-analyzed with improved analytical techniques in 2002. Child B was about 8 months old when sampled in the fall of 2002. Maternal values are available from the fall of 1998, March 2000, and June 2002, and as with worker #1, are provided to offer general context. Q`uSaanmtpilfiincgarteisounlt(sLaLrOeQs)hoofwtnhienatnhaelyttaibclaels mbeetlhowo.d,Ftohre rqeusaunlttisfibcealtoiowntlhiemLitowfoerrthLeimcihteomfica52 (where available) is shown in parenthesis. < 2m z 85 MEiER Bl > i [e[o Wn s [To OD[V8] [Freee | memoaom Perfluoroociancsulfonate (PFOS) wm [rowem[mweew[reown ] [Fm------_____J_om_[w| [F OYe [807e 00] Nc ea e e-- -- -- RY = -- -------- pe r-- --ree -------------- m me e Nemethy perfluorooctanesulfonamidoacetate (M570) + ferrrssnsren worsen ARATE Nov. 1998 Sample [2002 Sample. [r---- foe Sample reanalysis] [yo oweeo n fo | (0.004) Ry [Fr ro(0.057) [weom (0.001) [n/a] 3M does not believe that these data meet the TSCA Section 8(c) "substantial risk" reporting. threshold. In our view, thesedataare limited and provide no basis to draw any scientific conclusions. Nevertheless, 3Mhasdecided to submit these data to the 8(e) docket,withthe consentofthe two workers, recognizing the ongoing work by U.S. EPA to assess fluorochemical exposure pathways and potential risks. Ifyou have any questions, please do not hesitate to contact Dr. Larry Zobel at (651) 733-5181. Sincerely, JI Mi Larry K. Zobel, MD MPH StaffVice President and Medical Director 3M Medical Department