Document L1k5y90dkGKjZpVgDQL8YQbq

'p .irh n rn l sf -D <s> Z - i/> - in;i<lc plans for a s is tli sym posium w h ic h w o u ld ( o n s id rj a ll aspect = -* ci '-- ?. -- -z -i > X - 1 " : - ---- ; ? .= 5 -! X ; | =2 | 1i p = ; _ ci n S t * -Z z= C; ^ "=^ 3= ---:2<S^ '= ^ 11 I ' 5" = 1 -z = _ .= r' ' z'^ l! ~ ~z -z = - i X A' --^ 7 . -' T5 = .3 y-~ r i* 5 - - - t J t|| *=r s =S z z* z ~i . t = f .= r- ^ Z '- f -- . " = ^ f- 12 ^-- ? 5 1^ I -=- ~'i W arren Tucker H ieliarrf ('. W tifnu Ev _JD O CL CD < tf X - u s Cl IlHil! - - I ' .2 . = r > _x r. ~ cr - F ~ = - ? s. .I =^ = = 2 S = S |P 11 s ! H i= t' 1 i | 2 2r = Z.- - ~ -- "x " --3 B/: y -Zi |** ?-r- .2 -- --' 5- p gi 2 S 22 --2 > = g | =- g = I 5= i ~ Il = Z =2 s i-1 | f; = \ ?r tr ?- 25= . - f 11 5 I cl 2 ' =. p = ^ C i I I 1 1 1' 5 -' -- * 5= . 2 s 2 ~ ~ ? . -1 2^2 .:<.-. 5 ~ E/ . 2^ -.2 -- *" ^ 22^ 5 --i ~ - - I3 iI r T "= 1 i= a.4 I= -9 .2 = i'- t Z ~ <M L : i 4 -= 22 * " = 2 =P = ; i "= '=z *x 3 y- c- s i fl = s - ? ; 1 - 4, 2r -32 _r x -- - iE --X .= X i.X -Z 1= .C 'H= eit?9=r -?=== -=`rx ?IC iI.2I?s 1^ 1 ?r iii M2 II - =2 = e y. 21 &I = r 2 k =| nit I =i ^iI ~Z ~ S Z - ~ "S 2 r : r? = -Z = 2 " " f 2 ' "x _S r* 5x 1-- Ir Mi i1 n _ = = .2 " L| I ` | 1 . -- ~ . .E - Z_ - ^ . ? = _ ^" " Zx *x r~1 -M l a = I:fi ;2r 5j st i 1 E r= = f -= S' % z i i > = ^ ?- --- T ? ~ -XL- S? "5 r I ^ y. s- J i- lilt; l y _ = I $ = - "r. ? E 1= I I -= - " t - ? =? j i! * ; i MI'J ^ .= a t = I2 ~ :* >- ib - s 1 = -f is i * i NI I. = I" 8 .a 5 - ^r ~ .y- s. =- H^ill * = = w * .iH.iiil s 1 1! ii - 21j||4 = !SI-iill " = 2 6? II?- = r = = " j ~& tJG " 2 - t i r s - T2 f I I"i S 1 -1 " 5 ; S s <- --s '.= -- _ -- _ r. ^ ~ ^ ^in11 rrld-"I i I I ! N -M 1 i: .1 L i 5 1 -- I L- 5: " y- P X - li Ilf J = Sb.5i-r:r'ig'5 = 0| *3 S . S - ? = = - ^ - ~ a | = f % i I5M -ill : Ij I I! ? UI :j - H '= h n ~ < t ; s ..'s^^N-1 niJ" a" sIr -- = i =' i -- --= ='& S'fislt-g s= f fitl it- s 3 t .: 1 i !--T- ill II I5 iIIiI; t -- s E: '5 "f I - 5 ' ~ - - - t -H S .= > - - it - = I ; I r 5, - =. -- .= I'5 11 " . = g- --=" = = _ c w r v - . - ,= _ S S -is "c == " "-i ^ ^-nw tin n e d w ith o u t him . I nn m uch was at .stake fo r the studs' to he djnppetV, and lo rtm ia te lv il had heeome m ore than a one-m an job. In (he fo llo w in g year new investigators came into the fiehl. S pecial praise is due M r. jto w d ite h fo r his te n a e ify in the face o f diseoura^ine circum stances and asional opposition, in nearlv l\ve years ll'lz r* * .' 5 = 3 -g 2 = p r. 5. nmisii-Hiii !INiii;i s = j i i i' i f ? s " ^ -I I p il 11 H i i Cl =- j- - - : I > = ! c y .r i S == * " ;? f - '- = i i s si - i - ? = J z = - ; I ; ] 11 i :? i- ~ " *- C i ? ' ^ =j: - c = 2 L I i = = S' ^ -= = - imfi?; = 3 -ri J: ' Z'~>Z-BScz-r' . - -~ = - ^ = -r ? = ? _~ ^~ .=s Jz ? -i - Ei JiiJ - if; zr. - j: -3 l r ~ r ~ b ' ~ ~. - ~ #r = - = < t = t -- = 'c = -r -i ^ -- _r r = j { ;. - ; - - ^ -- 'J~ -~ ~ bt- = - i I' A = : .= ^ - 7- - B - ~ -Z = z _ ^ r _ ^J > : - F Z r ~ ~ " J; 5 r B Z -* r- .x tc = 11 I- i j B B i -af ? --1 .. s - ~ V. I .=_ r Zi * Li .v -MrL Sr IUi li 1 - ~ < Z 'J --:; t- b ii -- : fz -. : ^ !S RTM --B -V. liUlili C Bva ^ i.T c r s - f f j .i ! I = 5 - :' - J V? s = ill r ; : * i 1 I = -ar ~~ Z a f --~ - = =^ ; ~r ~^ 5= -i ~ .= g = Si-"=-z;' .* ri umi; if in I I I ^ p I Z ^ g ijllilll ~ i '=r%t | - J lio n s have h e rn taken o th e r than w o u ld |>e nsed fo r h a n d lin g o u liu a rv eoj>jer o r bron/.e. ' I should like to ask i)r. Jackson w h e th e r ;inv custom ers of the A inem an brass (Ininpanv have e \e r made com plaints or had lio n h le The M o n u fo d u re of Fluorescent L The M a n u fa ctu re of Fluorescent Lamps ;lnstrv. a lth o u g h im p o rta n t portions o f th is 10 per cent re m a in d e r !o re fra c to rie s and lig h t alloys. that tin* requirem ents o f the fluorescent la m p in d u s try are "n ;m . B iusli H<>r\Ilitim C om pany, C leveland, O hio. Present and fu tu re Uses o f Beryllium In th e short tim e I havt- Uccu w ith th e ro m jra m m v th o n n - fins Ix -rn -- I am just m rn fin n in g a th e o ry -- that (la- s u lfu ric acid ra d ica l o r tlio fum es/ 6 S r r ' ( :li;ip|(T M, `la. ( I'd ) J ;m / . n 'U t<> h e a lth in the lasi( h e ty lliu m in d u s tty . In H it t S lu 'le ir s and jus assoeiates m ade an iii(lu.slnal hy^ient* study ol a b e ry lliu m ju n d u e in i; p la n t in IV m is y lv a n ia . T lie v dism issed b e ry lliu m as a p a tlm ^ e n ie a iu m t. ;md reported atm ospherie roneentrations oi llu o rid rs and o\ides oi uito....... In w liie h th e y a tlrib n le d tbe re.spii a tn rv disease ancl d e rm a titis I . i I m i I v M u tu a l I i i m u i i u t C om p a n y . Iln s h m , IMa'.s.u I iu m |s. on co ie o a .= i .2 CL. < =6 I u = PC 2 i i = '- ? I - ri s = 7_ ? -f E S. 1I sll III ill 'i P 2 a s -5 ill I. I l1I 5 IU alii > ~ -2 st - s s f? = -- s. i- -H '5 -5 E 1 si ~ -- V! i .r l =Og ;l f .= - 4 "-- s1 t ez s. t ='i :? " 1C c plants. 1 11 first p a tie n t w h o m w o had ;m o p p o rtu n ity to s tu d y at th e C le v e la n d * ..... N "s p it;i] had h o rn a c o -w o rk e r o f th e p a tie n t w hose d e a th b ro u g h t l 'h w iria n . C lrv c k u id C lin ic, C lew -land. O hio. of-v li .2 ? g I I < -> z. -. >- V, ?. 5 =P I -r - - i- 3- i I 5 - P.2 i - ? = S-- ir> r - - 'r | 3 I ~ "' 3 = 1 i C :i- i sr x 2 ?- 3 = 1IIA fI % I = j; - ~_ - E .i * I , r: . 2^ ~ -x jz n r' 2r S S. -= j= i. = 5 ~ = " - 1 S ? T " 2 .2 2 | | 111 r i e 3 =- HI=r * - _ ri A ii l.l \ i i ^ t/. _= 5 E c * r~ - = =_ r - a -e ~ i i c z -zr ;r3= 2 - - - |- ~ X * V sI=I e t 2 : = l - _ 'z = 5 = . 3. ^ * 4- i = C S i= *= f = ^ -= .2 -H c_ " `x ~ = -= c E_ i ^s 42 -= ii. l' s Is 2 r-- tr. E : = :. Z l /r^-y $ W`' -- r _z . j N :: 2 r it z Nil ->I. ~r ,*3 3 3 ;= f= : ~ .2 ?= = , ^ --V-' z I 5 r I 2. Z Y 0 'I I I ~ "E ~ uM i -J J Z ^ ^ T= l ?. rz ~ 2 an allnv was not icsponsihle in that p a rtirn la i easr. DH. a c a ii-: People have heen asking me w hat m u experience has on the o th e r side of the A tla n tic. I m ust a dm it that it has been 2 r. ~ r tf. = 2 j= ^ 5 j= XT .2! = *5T rZ .= >2 = = > 1 *: .I I Hi * t-1 % 5-= 5S 7s H .= ^ .2 5 > il "1 T* r _ = " -- *7= J l-rsM- _ : - .= -- _c 5~ 7i 3 -J = Sc ti 5 = -= 2r c I l J 2 12 J% I s = I ! | I Iu s II 3 = = s ! 5 I .2 is* =c ~ >, 1 i= ?= -c 2 03 I " as >> = = ~^ -r: k w I'll 4 III * 11 >' i 11 11I i-i H ? I 3 I ~ -- t2 - , ; .2 c I 1 II Is 21 III 8j 1 i c_ - H r .=: is f I V .= Ch Jj* * 111 V .2 ^ f = *: 1 = ;e =2 = _~ Z" '5 TT - s-- = Zm -- fr t:c -- 1= 1H= 5= 5 " t ~ y- 2 J 2= = = 1 "* = i n i.i s r iH * - i 2 -5 z. k ~ = Js f : 1 I/T: == --r r1 : 2 .2 ~ |E S 3 5 vf - r ->: ~ = .p ~ = = 2 S: c= - r ~X " Ii I --c = r* .,- x ^ _r r" Z .Z l -5 "r: r -r Sc ' -6 jz ? ~ r- i cj S :fl 1 I -' I =3 = III ~ tx 2 js'a 1 :i ^ iir s 11, i'3 ^ OJ " _ 2r s' 2 | 1I= 5 i: = 32 - 3= -3 .r- l r| r P3 m<" I h rem a in e d spasm odic, o c c u rrin g a t irre g u la r in te rv a ls , p ro d u c e d a '< dust s tre a k e d ' s p u tu m . A n o re x ia a n d g e n e ra l m alaise w e re eon .....t in t s y m p to m s . <>11 Ins a d m is s io n to th e h o s p ita l o n M a rc h 20, e x a m in a tio n re v e a le d th<` p a tie n t to he m o d e ra te ly d ysp n e ic, w ith d e fin ite acrocyanosis. H i- 9911 > 9{ r< {$ s_:: ?9 J 9: 9 t-r 009 ;i a rr: -- - 6 :i ?:? -c : c c m: - c c _( i\ -- { 1. I9t r 6 ZiZ I of c C\ c U9T 5 i: -- I 95 1 re "7 ~; { 1- ... - "C ; rr:uc' \u r -'i:;inc spuonjj .j.'in :;r:uc: m:J i;qrquj stsrj Oiyq n ir ;c ri ra joints -jn< snrjjnc 3puon|j *T3;:sp:u -] \'a rt:nt" Oqr'jCjJ soucis sjcpnv sptjor.M -qns <ji}iq p^y -rnp -nuaprjp] 1------------------------------------------- n>(j <q f?snv: Oqrqojd <v<rp1 V.V.T.Wj '-Q StilUCMMUg I'M.so-jic-; jo snoiis is^iiw iv .uoivaid'3y o\\ ivivaarj v-,c>m.\ 01 3 ia Ainia^io 30 swc-s'viv | j j a-jav 3r6l ;rr; 'rtl co CO Zlf.Z-z fill I I g 11 r?||I'" = 2 r 's' 5-&J s I ill 5 -- -- 1M iA .... irji mi ini illltf I 5 's & -2 5 f l i = 11 s'J , - ' C =- ~= 7. S -..-=- r; "5 1 I I Sit ;i|l g.11 J . s?'nnn . 2 V y t, . J- ^ ~ z *. z ~ c i*2 =. = I J IS ~ 1- : I -- = # = :--< - Xn 10 ~ - -- _ l< r r~ 1- :, n * = i _5 i r -r . 11 z5. II $ 4 I "T* _r 's r .r | -. rX s -- ^' ; = a= - e - :-~ .5 mii HP 1 - t i s 11 ? J =i " - js *?. -= r- 5 r. 5 z = z_ - 7. l 1 * So < j it 4= . i n c r c ^ ^ Hn f p ro p !,- w h o w ere exposed. Y o ,, r fii>in rs xhoxc a g ra d u a l especially m disease traced lo (lo o .id e o m ,p n ,n ,,h . ,,IMr0 " .......... . W h a t is the in c id e n c e o f p n e u m o n itis a m o n g lia is e w h o " seal a lle rg y o r a h is to ry o f a lle rg y , as c o n tra s te d w ith those h a v in g no In contrast, the pulm onary granulom atosis observed in b e ry lliu m w orkers shows some pathologic features w h ich d iffe re n tia te it from other so m e w h a t s im ila r c h ro n ie diseases. T h e process is d iffu s e a n d u n ifo rm ly in v o lv e s b o th lu n g s (fig . CK)). M ic ro s c o p ic a lly , th e tissue re a c tio n is seen oCN uU}o ir wti uruuuujip* |v, *TinfJ*H*J {**>18 iiMott-ansaqr* f r*,J**i V* tjanuiM f"w"*m*om*OTOM^ ,1 * 2 ps.\(OAUi xj a tux ueXjo Xuy x 'pio^Jts $(3|Mog ujoj; ajqrqsmSumip ooa si stsofnaaaqni `auasqE si SIS0.D3U ;i DI3SIJ333tJtl|^ S] U01[ saqiJDsuiTOJp X]|ensfi -p^joaj/r Avouroi auoq pur 'i9.\\\ `uaa\ds A{[tuoiseD?o put pou |tuoitfa>} -ssnu aaBjaiuo]3uo:> aSaEj z\\i JO J3JU99 Ut JODX) Atjq ' UOIS3J jo aauassa sainapsuo^ i'P -jsqna do|a.\ap 'aaa `uwfds `auoq `unaq `sapou i^dtUA^ uoijnutjduji SMJfp aj* Xjsnoauranoqn* sjnooo uoif -yj -s^m jubi2 jtuoiseooo put saStqdo43tui qifaa uoij -tJjjyui Xq pauuoj uoisxi sapou jaqjo put `mojjeoj auoq `uaajds *j9ai( Xnaoi< -eax> put `paaaajjt poo qdiuXj |tiqauojqoaq3eJX plODJtS sipaoq aoj ruaiuD jaiqa jo auo si siscxoau jo aouasqy ujajjed (Baid.u ui sanioo suoisaj pajsaq UJ uont9sw safqiuasa^ suoisaj aiuos ut sjoddo suoi[ aimtuj ut paaunouoad X[aAiJr(aj si A[|tuo|St39o uontziuqt -a'pj 'sputjjs ui `saunouir l|EUIS A 3 3 A Ut SitOaQ sosai NVHX E3HA0 Q3.MOASI SNVOUO SIS0503M anssu snowiij uoisa| jo suiSjeiu it .\([tnsn anzoo sarpoq jtpioqa -uoo ou qiiM S{(a:> sutqa'uirj saipoq |tp -loqauoa inoqaiA\ punoj 5.JJ3D susq^ur-j {ediJa'x *uft3s anssii Dustfa a^fEj qaiqM sarpoq ftpioqauoa qjiA\ `punoj sjjaa surq^uu^ (tzqdXx uijseja uttjuoo aou op XjiuajtddE q^rqM safpoq [tpioqauoa qaiM `Jti59o sjjaa .sutqSuE'i jtaidXx saiaoe iva IOHONOD ONV S1133 1NVIO sujnidas jtjoa\jv VAOJJsap uoisa^ '(siEUiiur [tjuaujuadxa ut A|[tpaus9 % suotsaf A|jta auios ur jnzoo l sa^tqdojotpq saj.ooqduj\| : jo auoz jaano qat.u `paiutJJt i a(jtiptj uaajo `s|[3a ptorpqj 'ida Xq papunojjns sisoaaau jo auoz jejjuaa' \o sastsuo^ asnp S'ui -uitauoa sa^BqdojDtuj pajaaasas ajt qatqAs ut anssia snojqy paziuqt -A'q lpa[joqM jo ajnpou pauqap qa.vi jo sasisuo^ pidq a|aai[ suieiuod sf[aa auna' pur saaA'aouom jo ujsE(do:A'^ `ujaaatd jo uon EAj9sajd qar.v\ suanadas jej -oaA|t jo ^uiua?|afqa saanp -ojJ uoisa-j auasqE jo 3jej aju saatqdojaEjAj saaXooqd -uja| jo jt[[oa qaiM `sjjaa pioi|aqaida [eijX^uas jo ssrm aatduuoa jo sasisuo3 pidi{ ipnui suiEa ~uoa saa.oououa jo uisE[doa *0 Cssp-J^qna pioifaqaida) s3|npou {tiaXauXs aoEdiuoa uijoj aou op put XjfEnpu -ipui pajaaaeos ajt `auasajd ji `sqaa pionaqardg *uora -joasip pa^jtua Fuianpojd `sfjEAs je[03aie ur saaXooqd >uiX| puE sa^BqdojDEUi jo aata'ajS^E asoo[ jo sasisuo^ voisai avoidAi SfTOJtftf f/toJuM sywog jisojtrtuojnupji CittvctUfng 3SV3SIU AtVNOIViad dO S3dAX H.TOi iO S3tnXV3d DIDO10HJ.V4 318VX 205 th e einc, a n d Is w h ic h ? :~ 3 r 2 s 33-8|18 ii iI i*f1^J: S-ss zjtQ. 3 2 S s3 1 .& I ` --*" .y>. f 1 i1 --^ 3 J2 " *32 ifc 5= > 3 2 i h 3 a "rt 55 to 1 1 .2 s li * -l *s ; 1 J J 'tsSo . yh- ca W 8. 1 $ S SP ;j 2 SS S S3 . y jz to V, 1 c xy Cyfi "y X, " -= S3 j? 2 ,g 0 to c a c > * s <5 j1 $ y 'wy *1 y E 5 it 5s 2, X ii y IS " >. *2 c *s c " 1 y 3 ,y 1 y % x j ^ w. o *-- *- *5 w & *- w y y i. c B P n C. .a J3 ^*o ~. 3 0 > i: | y3 s3 3 <rt *+ e 2 .2 I V* = & & i v Ti- B 2 E. v -3 * u . C a c- *> 2 ! 111 S *tao .s .i i j 7, 3s a to * S ^ * "So O *s 1 vs 3 3 *. _ w' ^ *-. Cy -v4s *-* i fcO = jt J *$! 4-1^ ? M *3P 1 t- 3 ,!S M *V c 2 be -- 3t X X * i .9 8. a - i *. j 11 i % s115/5 .2 3= I i I! 11 ^ I3 O _ "3y gc- c> -- S> % lM 2* v~ 2 y ** sa r 13I -s S 2 3 i ill If* IJ I* -a 32 > |5 ~3? ^ y c > 2 - 2 fc C-iSS^S tO "5 5: tc^ r 'tC V sill S. a ?. o C Is * % ~ 3 .2 2 .2 "5 'S | 1J^ ll >S 4) c 3 8 ^ = Ss^> '_O^_ i^"32s<..515 s* 5 --- "y&~-3. |e s3 ^2 Ss jA 'rt H 'w D g * s -' g 5 fit Q ,-S .1 V5 8 x - V) W- *A c 2a " S .si >* .2 IS 2 .i*S c^ g*" .a - 2 3 | 1 & g- g, ** 3 * si s Si 9 2 i iti 1o a g -= ^ a ? M- ~ P "M r J2 < " H oi e$ *r 331 i pw ci s (2 y ^j?2 4H^*,^<yvsit*`,< 3 gs a 5 S -5 u ^ -a 3 P '3 e V) s" 21 - i =11 i ^ co jf J c V, .s r 1 fl C y "o s''S >3 c cs S -3 fc' O it I 1 * &y "Sc 2 ' +* ' ^ *- I *N w c i is 0 ye y -3 . *s &i 2y N y i js pC 1g-1^ gI* fo .i2 P > a js v o o tJ " V "S^ s 1 I g 31f a ^ 8 * B ca 5 ^l-sl-gt -- w> -o s _ J- 1a vs vs 2" g ii S S 5.-3 .c = 3 p CT' 0JI 0 c ~ C vj. o ^ w 11 g |>1 " B* - S V -= v. ~ = ^ o 2 ; "= j - ." ~ _ i~~~ = i - s *ii Ilf! Hi iiUitJ " := -S s I -s I1H3II z; 5 i! i i?* Si = I^ 1 = ti lii 3 u; ^= - = ? ~- C- -3 i i fj 5= - ^> 5 not w o rry too m uch about the delay in this p a rtic u la r disease. H e cite d tum ors, w h ic h arc self-propagating once tUey get started. I th in k th a t the disease w ith w h ic h w e arc d e a lin g , how ever, is an in fla m m a to ry one, and state of extrem e anoxemia and requires oxygen alm ost continuously. A fte r his death postm ortem studies w ill be made. 'D u* dauget to h e a lth in th e neon .sign in d u s try is increased !>v th e fa c t i 3= = = u-, =n ; C ~ > z c2 "= - .= ~ r-- = 5 2 a= 3 !_ ~ 6i UL 05 61 5Z sr ot 09 Si j, 3j tv itv qtuocu-5r yv |TAjnj qiuoaj-tl JJV t+- Z~ 9l + 91il699Z~ 0 ;o.l ?u; / " vuwffia 56'6 66' 5 LIP OK 5 6L-Z 80'9 it- 9 uv SKK i8'6 9Z'9 86'Z 99" ot- 9Z0Z+ oz- 91 + i.S'*' W* t-6't- I6'6 _________ _ :rt-- tt+ 99ZT- paiDipSJd p3UILUJ33SQ 3ffJV P>!P,Ji jo % T * jc.1 Suit7 . ---------- tjutjiffia - --------- -------------- HI K 8LI 891 i9l VZl ZOI 8it 8ZI oh 901 Z9I on 091 861 99 091 Z9I panipaJd pdUfUiJ3J3Q uw/jsv '7 u< 7g}Y 53llSmiXDV>iVHO arc.YiOA osm osv xnovdvo oKiHiraM KnKixvit 'IAX 31avX m *a IV *Z of *03 03 Til i ri s s -jj nC r- t/*> I5 o on -rr On 82 spsssas I |(3 . o rn * r"N r~- nC ' is H h r |O' Os ^ O' q^r^c = is? On O >0 -O SK -- 1 K- 3 t-z6lcl- uotiP]tiu*-i \ iv }u?ui$ iq 1C 7$ 69 0 C,, Cl 9 tt 9 IS St IS in jiy __________ mm r>ciiv<l 7 +t-t-t -t- -ri0 iulirj rmin'f F'^'P 99' IS' tf CK fS' _K T9' iZ' ]0 it- 9i-I M 9*8 6S OKI 58 9'8 99 tn l 98'0 96 1+ O'8 0" 9S i6'0 it- 990 t-8 K 09 O'O t-t- i8'I 18 98 iZ 67 ^ O'8 p^OJnSUOD lQ p9LJlt3Jq JfV SpBji ^ A`0 7 3SIDU3X3 IVOlSAHd Ol 3SSOdS3* onoaviajv asv A30AV3ldS33 IIAX ^avx qjuow-TZ HV il St IV O'Z z of f of D 57 S'f iPIN St ji-uuus; q-d'ui p>hns <N CO =M ~M *-~ = r , i-atrs-i ! I = 11 a! clear leukocytes ra rrlv are pje.seut 4) LU UJ CxL X QC < Q_ C linical and Epidem iologic Aspects c o .o u! smuoiunduJ [vonuaip p3.\rp<j siJtuoujnauJ [cDiuiaqj smSu.uBqdoscu (ronusq;) snt.MiDunluoD ::e]uo^) snuEousp neiiicr) 3uiuosHxi tunij|.u3g smuouinauJ (eujd.uy sunriuisQ SlUSUJjrE AJOJBJldsa^J nuomnsud ^rrmuaiQ 3n*:>i|is uim[[ usq 3S3urU'ui:uj :>uiz jspwod luaasajonjj spuony.vxo 3g spuony sg siEjins sg 3pixo sg jE)3ui ag 31C31JJS 3S3UeuEIU 3Q 3JEUOqjED 3g Jdp.wod 3U33S3JOn[J 3pIXO 3Q spuony sg 3J0 3g 3pIXO 3g 3JO | \J3g 9t-6I St-61 mi t+61 tt-61 (sstpj) .utqsjaqex put 'pJtH C!HO) PU5 puwjspjQU^ \ (tj) ,,> nsdsiJ-j put 3JX c*d) in sjaqjo pUE U3[iq5 'oiqo) at sjaqio pur purjjs:'i(')up.\ rtuoiunsud p3|j33-33JE| oiuojtQ srsoij[AJ3g sisojsps .urLiouifng suijotqouojq 3jnoy uonraixojui joJka iunt[[.\J3q-3uiJonj-j suqosAjr-oqoucug , J3 \3j 3iuni I EJ3J\' ,, nuoiun3uJ jo sujjog ^SfPUJIOE SrSOIJ[.U3Q __ suqoiqouojg snouiriQ spiJOfqa 3g 3irj[ns sq 3ptxojp.\q sg SJBOqiS 3g spuonyAXO 3g spijony ?g | E33LU 3g spijonyAXO 3g [ EJ3UJ 3g 'oo 3a 'OIJ3EJJX3) [V33UJ 3g pt.ijo.iut utmjjusq jo JV.'tUPcQ 6r (AUEUTJ3Q) j, J3A3J^ Of-6T 9S6I SS6I CE6T uotjtntjqnq jo *:pq (Bissng) M J3BJZJ pUB SlIA05[Jg (tissny) u, utuipo (XuEUjjsrj) 6rt jpJtqpSu^ pun J3qs twcftny 1v.1n1.1u3g 01 33.1SOdX3 33.UV 1DV HI AH01V3IdS33 3HI 30 S3SV3SIQ \\I 318VJ, c * ir =. 1J 1 1 si r= Z I Is S 5: i zz h A r 5 ci s s: 2 ~= 4-- 1- --2 7r I^ -= S2 Hi = jiff l-8|1 i M . ^ ~ *S ifiH 3 = 2 ~ I S 2 7. " .= " = ! % = = = i= l' ia= 2S %5 7 1 2 2Z i 2 1? 2 * =iI Mi ?. 5I c. *r .. X XX = 2 > i> i ~ 7.X5 3^ f 4 Z l s= s l ! 1 s i i -5 3.= 1 "s ji S= , S ! ^2- LO -"` il s 5 = S1 ^CX CS 3 A >J~ !i b c i 1 > -. B ijjIi|f!j W 3: z___ t -rg. - - - --rr ---I > .5 * . r - C'-i = ti 2S C - = -r rz -- v' = t/. ' -_-- H ~- !.= ? ; t ;x 1I b z-- - 2 2 J r; " ~ ^ .tr - ri r-:ii ? z = r- r -= - r- ~-j ~7. -r tsr _rx " / I r i- JJ y H ^ s- 5 _= a Hit 8 ? f * -i||| :Z -i.J - jc tc - s - = M:= -= II * v: -r ^ T ac | | E I j M l .S r~ s^.s siv ire 2 -I -r -Z i% | i ^ -i y f s ? s C ?.=* 3 -III -I -= - = s/. i1a 2 j! -if- i 2 r J =! s ! ! I! i 2 - * ~ = ^ U 15-11 ll rz l.IJ 5| i ci n 2 5 i i I = > P X II P; -= = = 5 r = *! N JlHt a j .: - -X s -->^ 5 " ?' s'- = ~ = sr. " J 5 = IJ 1 = - SC = 5 =J i 5 ~ *5 W | = Xs ^5 '.= .i =5 5 * -i - K H = Sf 111 B m ii.m c a n : T lic Ix-rvllii --1'"ir." e _o CH o Z> Cl. oE OL > <w O- CD *S>V .W^WWN'4 U-) a. < X u 3 "D O w hich w o u ld lie extrem ely d iffic u lt to crack. T h e fm m e liu ir o f all possible iu lo n u a tio n in to the research la b o ra to ry was considered necessary. He- O n V l, D iv is io n o f M c d ic .il S ervices, A to m ic K n e u 'v I 'ro jrc t, I'm v ris itv ol ...... 'lu -s le r, K o c lu s le r , N e w Y o rk . ( 7 ,:7 ) VZ *<< <1. > ( /'./) Co ,*N - 'if. 2 'C. z ? = 42 r~ z c -I z 'C 31 c | = p4 i ?' c = =t Z \n ~- 2-?' 1 2' r - ^. ~= 111?- '= $S < : >, 2 -2 c S. S. = ^ x X~- v-- I I zi --; -- fM ST mZ " -? c,oi Z_. wup ?cyc f7- F-- -- ^ r &%> x X s= c - -T Zx Io ^isfelv pH * f I L = : := V 2 'p . I It .mss !Hs- I : 5 i 1 rgl.I- ji i s1 Jl 1 = '=z - r~- ++ -- Cl X T ++ ? O -- cl sc- 4- + + 2 ^ c - w c: i IU iH S * ' ~ =,I4I 1 * i > s E? = B iochem ical Studies o f W o rke rs Exposed fo B eryllium 247 50 cc. s p e rim m nl n rin r0 : 0 I0 0 -S 5 ira d in u n l ( ,'n iriiia n '.p rrtio p lin lo irirh i 1 I .S I--70 2 I 00 50 ; = :f = ^ f' -7. f .X 7. ~r- -a Mt ili - = >s & 7 7 ._ 2 -s. =r >S ~ = > tJC - " --' a r= `Ui ! i-H 4o t * v- .= 2 a zf=- * cr rz := 2-1 = _= i= r -r 0:5r'- : . ` |0'-i JVUJf'lxJ S ilUO' r-p , *j; .Jrj; , v ,,, jy, idjiudr J :n ,,. [,,,V .................. ,_ r\ U ii 9 9 0 oZ ." SS : 1 si soi 0 0 6U h N sucmcuiiujajap jnoj_ \1 r ? s ; 0f : c t- [ q Is 0 0 3 3 3c r Cot) *S U pniS AJISJ .MU") 0 c S or Cor) 2 5zzr t: ; :r sc ofr . i l ----------- - - -- - ------------------------______ .. 0L 3 3xjojrjoqi'i p S()J\ ui)\; 61 6 05 3h , ) Uini|j.\j q oj pasoj 3-X sja.'fjo.w uojcjoqr-j i oz -r -v -: * -r -[ -z -i o -t- 0 ~z-z -[ -t- -c 0 31 0: [LJ noj IS qii.w 71Jf:{U lu Q[t- qji jJ.|y "uj ors qai.\\ J3](y rf.u oit- qii.w . p^ipixo /Uijr, jo uoixrij p/itpiXaUJ S1.V3IVOM 3Mn-NI3SOKOU.T dO NOUaMXa JUVNIXil 'HVXX 338VX m icrons. T h is a b s o rp tio n in the* o x id iz e d sam ples c a lls fo r fu rth e r s tu d y : see* w h e th e r any s p e c ific u rin a ry c o m p o u n d is re s p o n s ib le lo r th e meieased absorption. oC-<Nr 2 = *T t X C r, rs O K- .= 7 -f -: -z -r -r - ~t ! --t -t ~f -K -l -r 0 -2 G ui OK +i +i 07 *-52-5 -- t ~r KOI C06 0 OK 0 9 9f 0 WO ffr 9ro G c 5107 Of51 0 9S6 f 9 9f'0 fO 0 09 0 IO'f 9r'o + T 0 rs'O f-6l-f 6 OV c c c:07 016 0 f 9r 6 Z K 0 900 srf 9f0 -I -I OfO I 0 0 5 0f f 9 sro 900 85 0 IO'f 90 0 0 r60 -2-5 p a d 0 0 rco -52-5 --; eCc ; or* c -I 0CO l Off 0 f9 0 99 5 I SO 0 TOO 187 ffO 9' I 60 0 roo fro WO TO'O -ft 0 Zl'O -6 -5 p d d - - - -- -- -- -- -- -- -- -- -- -ff 0 50 -02-9 c 010 I o:9i 0 S 9L 9 f Of 0 to 0 97 Ot 0 c -- I sic i Olfl -ft s fn 9 6 :f o WO SfO Off 9: o -f 0 560 f-tr-f <? 7M S 0 9*7 -02-9 ; TIC l Of61 0 f fc : i ff 0 fo 0 067 or'o ::c r o::i ---- -0 5 SS C 5 05 0 too rr o t 9 seo 0 -ff 86'f -91-1 *= Ts -- -- -- -- -- -- -- -ff 5ft -02-9 0 -I OC07 059 0 -hi OCO'I CSS -hr f 911 871 rfo 80 0 -hf I 96 S'fl 2K0 500 rfo rs'o 600 827 ffO -ff -hr 017 -1-1 'Til 0 -hr 007 -02-9 6f 0 WO 0 0 t TO' E rsfi 0 0 ff 6 Z 060 500 rfo Off ero ^1 -hf 067 f~U-f c 0 5107 OOSl 0 76 9 5 ff 0 roo tr f fro 0 0 ore I cost -I Off! 0 S fS I 010 09 0 9i r ri o -ff +c 517 -1-1 P J T ,>P Srf v PCI in '*F u,\i 'T iuj `.1 "iS01 iw ATF-'-Su, -Siu '.7 ."ft.,, vrrc,i0 sjox: ""V] l"*u H'Q ? S3IG.11S 1VDIK3HD013 30 S0MU1NI3 3 3 3 3.\UVJ..S S Hd H 'JUAXX 3'lavX 5 HI ^ " .1 3 --s z~ rt% = E 5 4jf J '=3 3 = ?' i - s y. ~ =Q r ; B ~^ 7. " ? l r= r f LM 3 | ;j1 C ii 2 - E t 17 '= ~ 3 3 3 - ~ C = _ 3 -3 Z Z= '4 5 Zc - . = 2 i |||- I !! i = 1 | i i] ri i iy IJ i?i != I 3 = ^ - = 5 I ~f= 5 s -f i1t I -? -! I . : .= .= C u a s _v _y - -g = ^ * to? rs Sc a I. J ? i > fe t = r _ " > s = M "O O MS -^ V 4J 1a ini p .i = .2 2 .= = _ 5 =? r2 = =2 5- " *-.= = z-- -2 X ~x __ --- ' --z - r- zh ^ II . - -*s 5 f is f ~> -~ * 2 - '= .2 - 5 k l*-?: = 3= _ -- -- p : = = aJ: ~ Z si -- ; = c -5 2-?. ZT- . * k^ i 5i z ~ j* ~ = .2 _ = I: --- " -I H -r- 5 = .2 - 5 - * = wz s > 2 .2 3 ^ = ~ s. - .2 C- _= 2 -5 3? s~ s x tr. ? - s. -= *3 z X :: 2 z 2 *t - .= ' i " z I i I t ^ = -e ^" 7. 1 1 ?i I.= ; == n5 I 3= l* ~ -2 .5 == . II .z --z "9 2 = 2 =- = --z --y x-- 5^ =- "CS --- 5 = '? ?= z------ z 3| 2 .2 2 ^ .5 5 - > 2 -r = -J r; S 2S - " - 2 1I1I c/: -z M * 2 I 2 "- = = "-5 w --- <^ = 2 =4 = 5 1 -lit i Hi li s-H iff ISc- 5 3 % H 111-s 2z -2 z -- - -3 n = .= = i 3 - .= S~ 5= - =' T 2 I ?t : ? ? C i-i ll 1 ? 1 I 3 S" M ^= = -- ;| =I C- 2 =r " ?r =" = -= ~ i2s: r- ,i - " - 1:11 = 2 z~ 5 -- r* c. - E. i ei 2 I Hi!h!^ U z. I- = " 1- * ^ ~iz 1: !s z == .2 - -r S -c z t5= -= 3 > -5 2 2? - --2 2 " 3 =^ z r- .i III z. ~ -= i. *- -i- -r -p s i l ? v : , fl ; It Ii = "=" = ? -5 &' ? ^ =? - ^-- . -- i = .2^3 . = ? = ! iC 1 r: i 31 ill S -5 3I s' ====i ^ 3 fe - -= 2 It -: ~ 1 MU; .2 " | .1 **2 l| j >, 2 _= - r M .h i JS z z-- 1 2 unn i terms suggested hy the nom enclature com m ittee.) on. mu)i)KiN: I q u e s tio n th e p ro p rie ty o l p u ttin g th is m e d ic a l question t to a vote h e lo re tl\is e n tire hodv, w h ic h is com posed o f lay and medical - tf. c - - % -> x. IZ T. Z .2 i. sr r "r r. ~z s : II~ f- ^ = - r "? _r -- w II I 5 s 8 iJ O n m ieioscopic exam ination (lie diseased eves show ed acute conjunctiv itis and keratitis. In xonie anim als corneal ulcers w ere seen in w hich die cornea was leplaced |,y u rb a n izin g g ra n u la tio n tissue; in sneli an ^-ts , \ic n t and decree ol severitv, how ever, d ie jin lm o iia iy disease vaiied ,|, h am one tin- d ille re n t species (Ilf's . .SO and S I ). In lra -a lv e o la r edem a ,,l s a rv im ; decree, aee(im |)anied b y some in te rs titia l edem a and by 1I 1i l- 2^ 7. = =? M S = 2 ~ >-- I f= " ' 2 > = P i/. r 5? !:N j.;.11 hs = ? i -= ^= -.=I .=r Hi Q_ r ? | if i "cr e1i ri 5 .1 5 -S *3 Ii 5 5 - =_ ^ c_ |1 2= a > " = E. 2 -. J= "" 2 33 = 2 1E " ' "5 3 .a s ~ t- il y3~ 1= .= ^ =2 X -- Y 1j I1 = =I = i if} 4^ H 1 It H4-H >-if 1 a4 s li IIa a _. "H 4I >. = Js S .2 =y if Ii I~ t 3 C tl * -- -= s, j~ .2 _ 541 1I I s-s 1 f S- 3 2 - r: ---- " '. < f,i|^l> 5g S i .S 5 *f f = f"! 1 -s g =I r? rss^ fi i *511 n i "-- C- " JH  r -= sl UUsz Z ~Z .2 -iI 5 I 1 c- - - - a i~ = = 'i s ^ ? -H 5 5 _- 5 Ml 1 11 ,' 'i I =1 .2 Ei 5: s'? :* =- == :C E H ? if = ? _ -S'- -- s . ~ ~ st-sii s .= ::; * = !.= _"= = m li'if 1l t = .,, -I -3 - ? * ' :------- ' = = r: r- i ~-- " .2 ^ - ^ I i P1 .= i f =1 hJ Mill ^ ' r. s " -i >- *= >2c r~ _.2r _2 ^ i lo *" ^ __ J* > --- u MlJM r ? = " I - 3 ~f= J = ; si. 'Cw - r. _; ^ i Tr*- -*'. ~* i a. ? ? t -S' j; 1 .= 1 i *I I -2 - = s -= r = 2 " ^ ~ % ,= c : y j t = SI s= s -f c - S r ;i = s e ! JI- - .c I= ? *tit lI 1 - I- x= = -- - = .3i -f 2 =-- =>. - -I 3 ? c: sc :7 -- - - ,= s 1~ 5 i "r* si z 1 itf. ~?u . ~ = -Hi ? li : n i - >. -5*5 = ' -- r-- t P _ 3H i m- = = ? ^ 7 E5 ^ i .2 5 5 % us : s 5 2 " . m ;. - I r i; P=: .= .5 iS 4 ' 4 sc S I -- "r 1' II ~ P = =3 ; -s s z- = I1 n> = j^ =- i 1 -s p 2 sc 4 JM " 1 J= r: ~. - P - i V ZZ r -r X H = I I |SC -- 5 111 =7 I? = - - c -5 J3 S'- ic P2 5 ' sc 3 -2 *: *r.= .* "c r i-. 5 "= !!i1= HI= " '|,r = ! U II i -5 - i sill = := 5 1== ?I Bc^ 2 p1 ;- Z ~ '5 -S ^ .3 .2s. --- -- 2'52 S = = -5 i- ^ ~ 2. s: 2 2- -- z IL a - 2' -5 s s i- _ -2 > - 3 .- !!!l! If IS i ff. ii i -1 i l it i si ( % 94). Head, Ingestion T o x ic ity Section, l)i\'is io n of Pharm acology, A tom ic Knergv I :-'|ect, U niversity o f Rochester, Rochester, N ew York. 1 l le a d , D iv is io n o f P h a rm a co lo g y, A to m ic K n e rg v P roject, U n iv e rs ity o l Ro< h e s tc i. P m lessor o f P h a rm a c o lo g y , A'yhool o f M e d ic in e and D e n tis tiv , U n iv e rs itv til Rnchestc i ;= v* IX X X 35 = rzzsim ci tf. o= 0 = gI ~- 0 o Fi<;. I 10. TIME IN DAYS (h o w th cm ves oi 2 m ale rats fe d on a d irt o f w h ic h 10 pur cent was b e ry lliu m m etal. Mil r * - " = 7 ij| = P1 - 73 T~ _X -r J* 2 2 J= > x-- 1 a~ 5- : r = ' = k 5 -^ - $. s Ml HI 2- r ? * 2=5 f Mil= ? - .... ; ': 1 ?tc C ^ :* 2c -? ? = == I -7 1 -H 1 i t-- > ,, 2 - s' X2 I i2 1 iu n = *5 5rK : 11 5X Ii = -- = x -- "rc = - - mi r t = 1 = i J I\ K =11-11 1r = -5 2 2^ k -s Pi *1t *7 1 i ! J J! >if *-r i; f 5 * x 2 x s "x ~ r x 3 _= ~x . i ^i - i. -- i lr- ~ * - ~ - =S ^ 5 5 3|;i r x = ~ -- 2~ = illi. i -- =f ' t -- S :- .5 ^ >, i -= n; ~ f ' = ~. = k k2= Vxxx 132 z 2 % 4p SJ = 111 2~ *~ i r-s = = = r -tr- ? zx = = ill: -- -- r. iu (i i \I ~ `'tr - =1 I '= f 7= =7 - z> II #I -s 5 t zZ r= w ^ ~ 22 I 1 r -i ki ^n ~3 - 3 -k - _3 S = : 2 r=- = 1I = 4* ^ S' ^ -I1 H^ I . 3 'c k = 1 I x-- 7 ^11 = ~ > __ r 1I I< 5, 3| tr P '? = - 5> k J5 1411 * aT s ?f ^^~ 2 1 =- r s 4.4 | JijC 7= k k/; lc r-: ;/_ 2^ ? ? --' V. H S81 g #1 III ^c -III 4 I 11 J = 1 8.^ I2 I i2I 7 il ;1^ id i 2 = ^7 - x -- _9 "I i1 :s 2 = > Z- = i ?- L 3 -: '= 2 L. 73= -- ^11 .= 1 4 lit : - = > g -= C XC if5 5 ^S 77 l' is s- I ~k k2 i3 -- ?- I s3 3 I J s 1 a/F onl(`cl .some o l> srrva tio n s. t = -= 5r. B ? 4 -2 ? g = < 3J 7 l .a >. a -- X = 7: = r- 7 till i- ^ * 4- *" 53s S? t = II '? A cute T oxicity o f B eryllium Injected In tra p e rito n e o lly 2V9 =H - 2 2: I5 4; = I Js 1 -5 l -- =2 -i - 1- S-ll ilM r .2 i,;LM l i~ l slfsI/t I ~:-| i = <C* -- NC : 8 ^ X X S 1 4 2 ,,_ i 252. 3SE= ^ i =* j; o a. < X <J ==-- = * S> ~ 2 I I -~ ? _- 5 -* :r. 2 ii i 8 ill ^2SSSgJ|J iiiN IN fN nllHOH 22^2222222 'bc-C',b,bKb'b"b*b"b %; I.H ;3l < < <'<'<< x x < < >. L* 2 222=ZZ =, 2 = = Z =Ti_ I IrMHIill tb e is !! 2c --2 -' S'- i~ `r--TT i>'2 2 -w UH = = i . Jf^l ll-M I H= i i?= H sJ-M :. f I ;z- - ; isZiz ftlz* it i oc-) 7 I= ? =- ? s. ?, 4 i1 z i I Z- z I 1 .2. z j I o i.y X 'T=r = = ~ zf. Z :- r. 7Z~ J- S' -T = r ~ 2 t .2 .2 5 rS= .5 -:= 7 _i. S2 ~P rr -2 ^ ? O r x Jr 41 31 r>\ ^ il *5 .= na 3| = = = r co j if I | ? .= P $ ft r= ^ r- ~ .i .2 ~ - r v- 3. - ? Z -- ~ r1 - r r Z. ~_ --_ r ^ ^ ? ?* s= ? "2= ~ w7 ^ r ii;:. :r. `i i ih o CN Q IU l-- a. < X u a. .2 2 r r I t is in te re s tin g to speculate th a t the b e ry lliu m c o m p o u n d is su fficie n tly active to incite persistent p ro life ra tio n o f m onocytic cells { granulom as), hut not potent enough to convert the m onoevtie cell into an epithelioid - v- than I cc. is the organ w h ic h m ost o fte n serves as the p o rta l o f e n try in to the hum an hoilv. A nother advantage is that the technic docs not u a ju iie the engi- J'roiu the f i li i.i I H y g ie n e Set lio n , D iv is io n o| I'h .u m .ic n ln g v , A tn m ii `ueg\ I`|U|, e l, U n iv e is itv 1)1 ltm hes(er, K oehester, N e w Y ork. P relim inary Studies in the T o xico lo g y o f B eryllii >t-vo ?* -xj u `r *i j- ; i ixi jtijajruj 3*u t pkKWJau : ^`X.? , ->J 1 ,p fltlU'Ut JO ij^iunu ill p"JiJX3 ?l Ajr|TH<'V\ I0 I0 I0 Z0 zo Z0 zo Z0 Z0 Z0 Z0 z c Z 0 t- z Z 0 fI Z0 Z I 11 Z 0 Z0 zz Z0 Z I z:z hz Z I vz zz Z0 lz z*'z z:z ZZ Z'Z OIO'O szo'o OSO'O SiO'O ore SZ'O OS'O sro 00' I sn OS'I O'Z S'Z O't* 0'S s: 01 SI oz Of ot- OS s: ooi SZI OS l s:i ooz jptJo-(q: 1 iv^iy 'srf[nr 'u*7 tsrfjns fpuontfKso .......... smhj 9PHJt,D "unu.yg sspuoqirp) ?pi-\Q icfittn K/'otj i'y 57y h ' * n Z0 l. 0 Z 0 Z0 Z0 Z0 I0 Z0 Z0 t0 hZ Z0 Z0 Z0 tz ZI Z t* Z z z ZZ ZZ I I ZZ zz S/0 Z,0 S/0 z/o S/O OtO'O SZO'O OSO'O SiO'O OI'O SZ'O OS'O SZ'O 00`l SZ'T OS I O'Z sz O't* O'S S'i OT SI oz ot otOS Si 001 SZI 0S[ Sil ooz ?jvfaw -u'7 sjejjnt "iiO tjpjjnj ipuon^KxQ iptjonjj ?wj tptqjpj u.;ilCug ijpuoquej >Ptx0 : fpl*W icjin.n (pocj " ti(I sasnodiNOo Dmviais aiHio aw `saxnOdKoa j\nm.U3B `iviaj* K.iniunj jo sxoudh/ni iv3HDvjuvj.ni oni.wotioj #.unv_uojv JAXXX 3'18VJ. trim c li 888 v-> c ^ till c u ! HJ i3 =.. 1! 5 5 j5-= IjjJJJJili I lllliillli ' = i5 1 I5 2 is i nz -5 z: --- i. !! /i y>!r rt vs os sq , COp^OOC'-mo'oOOOO -3 ^ ~~ c c / sc OS * ^5! el ii = r 3 c: 'S3!' ^S 24 I 1 a* I'sasl'Sj sc-sl-sl-j s0l3 = 3 = 3|3l3|3 I '=i i -s If 3 ba I I 11 ^ Sx- "3 I f . | " si ^Hj I^S II m/Cieqitaij \ ^ _ jo ' ! os j^tfouirog'. -- d6 SiP9pntioyb*ouiL{0& ^ l* -oH ^ ^ ^s O | II i. 3 b '= I" s bf i = =c :- sT9J.U0Cfd^(~l Ij $ 5 S S rjiqdoutsoj 'J^j ?! g g- B till - s -5 t 1a l* - ~: M 5 3 i2 H s; *= II rjp?pnuoc{d-iOiaC{Od n 08.-II S '<>H <U0llVUUUm?(2 jo ~0^T e *r>J ? 5 v2* S Jill ~ i 2 " 1s = 2 t I S .1 " I X I III! I < :- 12 fmfe H uJ 4 2. "= ! -= i.-3 "c . - = 2 3 - : d 3;2s3j luma* 1 s f 11! Tt . -- tr. -2 1|i!11 MUM = =:= = .? : a?-g =1 = .2 = 5 if = 1 = = -- >x " 55 = S -5 $ s = iii .2 -- s = : = = -- 2 i 5 J "-== ST' 1 SI I " ^I I = c t/. `-z " > I 1 7 --' ~-- r i; * 2 1" "2 5 ~ 22 .i I .>2 2 j ! i . . - -i r- ** In produce massive accum ulation o f dust in locali >1 th e m a te ria l is not a cco m p lish e d as in in h a la tio n . " Itc s c a irli A s M iru lc , 'I 'lir S u iu n .lr | ..ilid l.ito l V, S .ii.m .ic !. (I St lli.ip n r 25. ( E d . ) I're lm iirio ry S tudios in the T o x ic o lo g y o f B e ry lliu m 325 s m k i.k s n y a k : I ju s l w a n t to k n o w il, in th<" s c iic s o l e x tia fa c to rs , :& ^ it -3 =f' 3 2 ~ *= o `rr -s 2 s~= ~5^ CO E 3 i* g ^e CD 3 -o u" II ?i -g "w 25 =2 <c -JZ ~2 a. "v < Kw X om u ~D c 5 _/ ~< *2 "O J <0 S a 7 I ! =' S - -- .x ~ _z =1- = -- ~ r- - Z-- -- 1 = =-r = r- z" S' Sr. i' i i=s li -z = -J! = E =" = I? Si 3 ~x J *= = o >- cc r 1 N:s zf- > ' ? ? .= ? _z *1 S 11 2 |P ?-- E s -5 i i-i : ?T T => = _2 S~c ^? z-: =- = = i n j *& _n .x II b P2 r5 SM 2 -XT = ~Z -= S = b ~ ;. 2 -- --E =X = "c ~ = '= Z -E- 5 Ml: 7 .z- 'TT ? - = = S r- till P ."2 t * =j Sc Sc . 11I Ii "'ll zr. z 7 7- ? > ' ; i 7_ ; a -- s -2 15 1 '-2 ? il3 l .c b 2 E. .=' =5. == 1 -. z. - s s = = : = -i t 5I E-! I s, a h = = j; E; < 'll-s 1S : = ci = Z EiI 1 = 5; E = =- i 5 ss i ri? IHi?!lff4IIUI!ll!l1 illllll= z e; C ' -= - r* c: = z .2 = .i 1 II I|J 111 III I - " ^ II J 1M 4! Fl7 = i = -; E -7 - =M= --b .l2 57 b5 7i -- ~ C-E_2~ .. i = E . ' g. IE be i= E -- E 5J _" | J 3 |M z1 x |. r" N 1 * -fE-p-.b-ESE- 2 " - b = = _' '7 ~ : E ? C s : > -S '= S 7 t t "E : : i i 1 - I i > J = -5 E ~ ~ E Z Z z .9 | ? 4 `B "T- j!J = -5 3 rFe rs * E 5s2 _ fr/4 7 z S E ~ FI f l %| - v: = b M 5 11 I i il111-=' E = * III^11' IIrr " -- S Pz ^.= i SE -- Sc ^ xr sc ` - ~ - = 7 ^ v. -- ~^ "7f .z: r* ~ r* MM - '-- .E ~ -~ i _z z - = -- r =-- =- = c^s = - I i ?, r r-- 'f s rr f z -- < = 7 J ^ "3 C pr. 5^ zw rs z lO = C= ~ P z 2 7 .E 7 -5 I ?c Z l -J -z *5 c< r P E_ 1 =w -< -- " = - r> ^ .. c -r w M i- > _Z - -- " ui5 e x F: 7 j 7 s2 " .b " b. E E ? B= ?I ~ ~ -s. --VE ^~= " y. ~ = - ., -- j 11 <5 " -3 .. r z 7 =.: J ~cE i i -r 5 b- d- = i 7 Sc 2, Ol _P p p -X ~ > ~ 3 -- ~ 2- 7 r= " ^ ^ Pf. y -- .= `f ? ; in Er M = 113 I I ~ 1 J I I Ui Fl=;= = 0 E. " "2i = wr i -- b = P Jz ~ E- "s ? r yi- rx Hi j 1 M':| = --'= = - 5 b-- E^ E S *=' S' 5 o' E .E .E ' 2- = e x 1 S -5 I rz I i I^ 12 --S w J *- "" i. & r E E i '! i- tNi = h l" c i4 `on Vhe legs a n d b o d y >1 the second dog. \ .small ca ta ra ct was n o te d on the le ft eye o f this anim al. The highly acidic chaiactcr o! this beryllium com pound, no d o u b t, was responsible fo r the start o f u lc e ra tiv e lesions observed in these exposed anim als. : s li S j o-7 I =_ = I 2h: =- 't i i- x =2 -= . 1 1 1 1 H 1 x r l r 4 "= .: S- I g i lB B J s'! 1 * P |i 2 o 5P Ifl - j = s 2 " 3 i .2 The red blood count showed little change. C lin ic a l C h v m ie u l Response. The c lin ic a l chem ical values indicated that renal dam age occurred in the rabbits dm in " the second week of the " O btained liv n iiiltip ly iiij; llu; p m rn ta j'r nl neutm pliils by tin- num ber ut w liite i ~ = f i 5 'Z A i Ik \ V -r z ? j JJ UX ~r 2~ i A :a :* nr. ! := 1 i I i. ii 2 88 18 8 III lif 'A, 11 s <*' _ a 1 2"- nit Z = ? -r r 2 - H `Z -- I "5 - * T- b _5 II --r ~" a ^ tf. i = ? g '*='" s -T S -- " -X __z ~ i J: ~2 S c tr. : X s 5 -ir XS f i $.- 1I 22 2 -- '-r -* 1 I 2 3^ - 4l2 =. b C_ w. z -b < >. ? j| Ifr 5 wr c- < ^ = ? -* S 3 1' j 1 2 vj 3??7 S ^ sfr. - JS 2 ii I? I- = ?i is 111 !J.s Jl WWW 5 .= = .= 5 2 2 Id HfH = 2 > x ?. Uiil U <<<<< r a^ .= i -= s; =Z?s 1-- i*"* 1- l L_ -- it = = 1 : c- JC ?c -7= J .2 .2 .= w > 5- I X s> JX i ". H 32 r- 1.1 4. -2 7 -7 y- S- -' =- =~ - - >. -2 . _ is "3 i = i ; L ^I 2M Sg 1! TC S Vi 3H = j j| 2z2 " - _ i 11 I7 H-2 1? I! 3 < -n v* - = i- ; -- w -- - & - if 5^ . t^ 2i. .s* S> iii S; 2 v. 2 * ^ A. 3 'J I i *. - E z-- = r= 1 s -. -z = ": = "3 = `o " > i- - = = -- ~ . i. -;n ? = 1 :1 1" jJ i s- 5 :s Ssr . "s- a. 3 az i ~= ?z ^Sl 2 1` 31 2 i! ^I =S c2 ? =^ ^-- S-- ' - -- y - z. ~ i - If- fzf- ~ !l;1 2 - -S : :li > = = Z $? !:>,$- s> a! I s ? r !1! -- % -- ij. -- rj I-I i-if I 77 1! =n 5 ~ it 7= . tb z" 2 = x ~ = -7 " -z =- 3 i S = - : - I = 5a = -- = 5 ~-- '= E =' -- \ \ I4 11 r' 7 z- 5 Jr ' tr. Z-, = =r -- it 7^- =i = 1= M i- II' ii i;r ~ 1 m ii. d k i.a iia n t : W o u ld it be possible to c o lle c t some of those fum es and make studies by means of X -rav diffraction? m ii. i .a s k jn : W e have c o lh 'c te d th e m , a n d a lth o u g h it is possible to m larjii.iimnn 14 = g I 1 tnj 2r 4sr = Hf - c L < 1 , 3 = T3 = z x0 ~ ^ ~- - i r i * c= p .E 4 M-- C 9 >. r; r" c _z .2 * _2= .si 2 .2 ~ l =_ -- I~ o 5P 33 . . -= ~2 _= t- - * 5-5 5 si 1 4 42 f "? 5ri * s~ ~ != M ili ~ x ~ ~ r-7---.i3= -_=<2t 2 -- --;--= s.--~' =_ 2 tr. '= * I 11;1 - Is ; : ? 2 ? == '" =- s = a m.n it = .rii j & 1 ^ ? * J-is ,, |? s --- i " .5 5 " -5 -* 5-- " = Is s -T - -- .x 2= ? Sr. - I1 !n * I> P i1 Ji = -2 - = ~ ? b " = 4 " JrLO O ! " c ^ =.: U'NI _- = ?i ? ? ? J~ :i i -=3-J-= p I -- = - .= = -- = =?= /-;? -= < ^ = P - f- t 2 > i`"?-'.lSs3Ol^o 1 s -= z S > - 3 - i 4 2 -- ~~ i 1- 5 = "s ! ?~ | I= I: =X 4 5415 =2-3 ? S 14 i f " = = - 2 i^ S ~ l r '= 1 II r44-1 a 2i ry 4ii > ^* - C= 5" 1 I4 P 1.* =- M 11- I I1 ="3 E 3 CO "U o "S I < X u < s 2 j *>> QC um*i o A n A n a ly s is o f D ust a n d Fum e H a z a rd s in a B e rylliu m P la n t 361 >3>o .\J0irjiJs3J .\ur]^ SIili euu3p bnOTJ3s l^j i i3sr? .ucucjidsaj 9 ''SJOJD^ds ur"' suurunsp jouitn aw \ S3SE3 snimujsp puc AJOjEJidssJ snoJ3a:n\ SSED [E1E/ 1; . uom'Jnp 3UO| JO 3SE3 JCJldsoq [ KAOStiq cfijnjj CP9 '\wm sq :jfHX `JH`''i39 `vj3gr'^HX^ J s3snp PUI' S3iung s:smj apuony ppV sauinj pur sisriQ pur `npj `(>9 O30 jW S3SHQ cOS `Sn0 `$9d i S3Ujng fOS59^ S3^nj pur s^silu ppV `OSa9) S3iunj puE sjsiui poy isnp 3JO p3SS330Jg ssiunj ;0!S jsnp 3JQ spuflrq jerjutjod Jofrjy s:ch\: apijorqj piDy uoqjyo -n^) sx'hn) 'O^C'HX) WH p?ppe ipunodutoi JtqjQ |e:puj sg 'WOhx) 039 n3sg o3a oa UOt] -onpcud [ri3LU ujni[|\j3g UlMJDnp -OjJ J3dJo3 UJn!||AJ3g uou -3npojd apixo vuni||.\j3g O'Ht" 'OS30 ow-^g 3JO p3SS3DOJJ 'O'S^crivosgC 3JO [AJ3q A\E}J Tpunoduio) tumaOsq b u iz 111 cas.Cap) lU3Unt3Jl 3JQ S'UU|3LU 3JQ rrt.'ojj sa.ctodttoo sii asv ivisk ao souonao^d 3Hi si sosvzvh ivixsiaod qkv sasszDond ` x'TX 33qvj_ s --- i =4 7z .= Ikl ? ~ C 3C -iC r rl > -z --z -\, \Z= ? Z -- 1- .z = J z: -- z __ -- = z: -- P- = t/. zJ zz _ _z -r -- -x P --_ =~" cz", z C_ zr z =r-| == ?- 5- Z _ = 1 I2 .2 f t 51 --< r. ^ Z = c4 5 -M r *ri r .2 -- r *; -- - .2 =: -- r >. ~ - = - " st 2 nh Z-- Z-- =C^_ . z ~ 1? i= x _ y- z`- z" X = z z: P ? i i 111 ~ --r S7 7 ' 31 x Z ~ _Z _r = 1-1 ? If- - -2 E ? -z 7 22 ?E i : - :-- t -> 2! ~ = z := --= z =t e j = 7 ; ii il 111 "y 1.J 1 111r! ? s I M Jiiif-- -- 2 y - -I 5 Z r = il!;:J p ? t F i5 ^ J 1Z e2 z5 z -- _i - j z 35 M ^o 5 * x =c "'f = pr. I I 2 __ E2 E = _ -5 1| L -' = =I % = uu =7- " e MM' :5 I'i e 2 ?: ~ 11 ' 1 >c- --2 il|f Z Z ZZz r U ii 7- E E 2_ =t '-= _ :7 $ 2 i. -- -- Z-- = = = - Z ^ - --= tf. _z z - --z Z = z~ =5 Cz- .2 Z ~ -r X _Z * = c~ _ E 2 .2 2 = = yr >. " 7 Z z X| I * X .z > C PZ z-- = E" r- ~r ~ = T -2 := P XX = P-5 = * -X ZT .Z -= ? 2 E S = r: -= =M 2 ji: 1r z =E : 2 = 2 > 1' _ z Uni lu ? x " ^ ~-- So_ * Z^ . r_t St ^ -s ~ 1 = *IH >r 5 z Mil I .= . E '-- 1 z l v- ^z - ~.Lr/- -- 7. ~ r s - f ~ - --x r i^-2=<E=:=Z i^EiZ 1 r?? ifs: 2 =Z ^ I yp - s U JIB a J SP .= " = '4* = I 1 -3 =2 - - E ~ z~. z 5 _i -- - zz y 2= 1" 1i :=1! 7 E l fl 2 = .2 Mil 11 E ! 1 f> 9 -1c ss = 1= I,, " z'X z w ; Z- I I S ! 1 J ! 1 M -v -Z 2 - Ii Z = .2 r x E: -.Zr s = z=r 2 " >; r c s=t -E- -E-- I '=. zc 1I s 11 il X P'_ z z - ! p 3 = = i c' ~z :z 2 --- -x yi y yZ P - - z: 2 ^1| = f i 1 ! ^ I II= < Ji: l1 4 !! z1jM| 1r112 ji y 2# 7. xr z C rZ * z- ~ E S ^=r- = a Z z -_ I - .2 * J 1 il %.= 5 ? .i r f Ie I ; 7 :E~ w .Z .2 X -- z= E S E -- ? 'r _ zcr Z5I = ! j 15 X .z 7 2 v. r e s .r i y 2 ? 2- -Za Z= r =: 2 zz r -i^ 5 y. 2= -- : =I E E - .= z- S = = *Pz -X- Z- =- `TM 55 * 1 1 7 .Ez2 - 2 s sJjE r " tr. Is il.= -T ^ i r=i_--z --z ?V .2 2 5 z -s '=. Xr- I- % ft 3 i = I= ?I iJ 7 5 I "Nli y% :hu - Kf i 1 1- w -- _Z I 1" i C - = > X x p zr r =. ~ Z i . r- _Z _ - "= s - X .X Jjr ,E E - == i 1-- Z r I!2Z b = l iiI = 5yx -3 .2 E =H z zc =?= Z T" '= =1 s sc |t "P S = -- =5 -E - liU Ik `Ug 1 iN= i 3 m? Its SC - 1111 o ! X 2 S rr = Him iii11 iifill -jin! IHl! H 1! II Ui i * -? -I= i:^ 1i& 2 "" .5 .1 = 1 =c x-- = -- J2 5== E" 1 ? .= -= 1 5I -2^7= III A n A n a ly s is o f D ust a n d Fum e H a z a rd s in a B e ry lliu m P la n t 367 rl-o 15- A" 5 [ku-iz purOt-F 1j.\ ' ti-'ouj oui 0l-r 6l-_ 09-s 0? r 501-5 JA f[-SU-p JA ' f su-p H J\ M-s.\cp i 6:-5: It--Ir st--sr 6:-:: 59-1: Ir-t-c 0c 00 00 00 00 00 00 0z 06 00 0 06 0I 09 / v riH >i :-t ,1 , ,r.. -V A-.,. c yt-61 0 5r6I 0 6661 0 5P6I A-lOlCJldsay [visuj iuni[[AjAj 9610 966 [ i'i D13OJ0JUUJJ3Q |u:^uj iurti]j vjag 0 9661 0 961 z 6661 6 96\ AJOJEJlds^ ah|[c jsddoo tun11j vjag 0 9f~61 566[ 3|30[0n:UJJ3Q AO[[r jsJJio tuni|(\ 966 [ 61 [ 6661 9 5661 .uoirJidsay 3puon[| uini||Aj3j 03-0 rc-5 9 ~Z~i 06-S i6~r !(} [ pur on-: 6I-. 61-5 51-9 01-3 S'B<X no .V/Z/y SArp f9-9 5-'tp---"9 <uu r9-SAtp 5 \ C- IU1J l : I- 'up01 ja <; 9-a i:p f- SA'up zt-Zl SArp m-F SAKp M-t <Arp zi-Z AVii.'p y<? <95-81 55-ir i9-ir it--it - 991 99-SI S-ir 69-6: 5t~U 85-91 'SJKP .vSt _/5 ^SFrzr^ 0 61 61 I 5t 91 0z z5 Z c 00 0 5* s t-t ~- o$ 15 r9 o < 9 :: t- s 9 S J JV -- [UK>X .> -'J jo 'X 9661 5661 666 r 5661 9661 51-61 6r6l tt-6[ 966 [ 5h6[ 6661 5661 DlSofOJ UUIJ3Q AJOjirjiJssy 31JjO[OJ1*UJJ3Q JP'\{ fuiuoxio& mnijj u?q jo fuotjpjssfiup\\' a .uv'w iv nvi.sosiod i-c imAass .10 .aho.isjh j \~|\' HTavj_ apuonri uinriiAj3o 3jrj[ns tuniffAjag 3}tfj|ns iuni|| a jag punodiao' Ult'UUHOf'.ifi % n~ r- i o = -6 ------ --= i p .< = .id 7 5 = V 4 - s r = 3:= 5 c *2 > xz 1I = = '= fl ? 1 2> 5s * r! n I 2i ? *> .5 li- l/jiill 2. =y r* 2| "2 '~r =' = ii J2 > s- sa 2 ^2 ISPS C ~ M ESS CM -- 3 SS5 [>t; b'T-r 9'9 97f I [ - ; r 60'6 .5'SK`II 6[ .K .89 it'O 8?'Z srz z If ff 9661 *9 r_e' fO't 76:`6[ t-: 6S fn 80'0 fff zt-f T 06 It- 91-61 on tU'I 6fl L'Zit'ZZ of 68 61 I f0 80* t Z6'T 6 ft :i 6661 00*6 sr: st-7 6'9LZ`SZ Sr 9zt ISI 00'I s:z Sit zr ff 96 0-61 :*ip: A/JWl'/f/W finso&xt 9fj[ i jv lL ysioj4ui .Outnbtjf iitxj 'Ji>tOCf-UPlUy ,'jnrodxi <mtuoui 'ay J IV |C)OI X3$ -------------------------------------------- cfiuoiu j4 ou my i }\T X3$ IJL ---------------------------------------------------- qiuoui W 79SP3 ou 'ay iK X3 ITM\L ----------------------------------------- s?:v: 'Oft JW{ a ixvm xi DXisosiod mm.usa io s3ioN3.ib3aj 3svo 'J].\"]\' 3'iav^ A n A n a ly s is of Dust a n d Fum e H a z a rd s in a B e rylliu m P lant 371 u ih I fluoride operations, how ever, were ascribed rases w ith both respir atory tract and depnatolntpe m anifestations. 'D ie general p la n t history shows 45 eases fo r It) Id. a la ri'e n m iib e r I(n a plant this size, d u rin g w h ich tim e d reported ic s p n a fo is fa ta litie s :: w -s'- 2 0W 5 rV D :: : v'UV''"'1 ` , w v: sS s. SC e.c.; A _9 v S' W( ' f:ao(f{ ,=<] wc: au 00'0 00*0 CO'O Xi'Z iVl rt'O sro ft-'O 6<'0 tr'O t-t- 0 'rsn'ojjM.' \:ufnbuf tetr} OO'O 00'0 00`0 SS'I 'l LY0 ZY0 tt'O .9 0 0? 0 wo ijJUOUl J.'L :hv: ou >o:rnd:."2 mIn i<^,iimi > jv.imrH'jfl hli.w nsi.snsiod isnrnusH f ro ZZ 0 :eo 6I'f t-S'l T t'0 wo 6F 0 St'l r$'0 99'I wtfl/i/w.' 'j Ottwfoif ifi'3 wo ffo St 0 LYl SO'I $Z`0 t6'0 CC'O set 00*1 OS'Z tfJUOM J'</ r,o'.i -0 if/ ou TO FF6t t-6t 9t-6t 9t-6T St-61 tt-61 Ct-61 9M5T St-61 H*6I wet ao{[U n>ia jnaui mru;|.u3tf spnony lump udff airjjns Lunip.ustf VUHOjUiOJ kV-oh isvd JO SOI LV13MMOD xnx 31'l ISM 1 11111i -' J- -- rw .J. ir I! s | 7 r - 2 .* M 'M. -- -= II 51 C- r. ^ 11 I c ^ r- ^ =3 & B3 S S = I ~ '3 . : 1z ii ? S = 2 `r -5 t- " 2 s I : II -- 7. 1 = I|f- ^ r Js M- : HiNf^Jrii HIj j ! l -. ^ kill e s; p s - 7 f ?- ii B I5^ s < 2 " s 2. L I J * I I- > 3 ._ * Sr. 5 ?= k *r ? =* ST T7 1 -n: ui 111 .;r -s i --r 1 i iI fi ifr rs isi I i 1.5 U- 5c n tf 'h K5 ^ C5 5 - is 5 I 53 - -I 51 I - s_.r i - :c 2 = 2 *5B J*' ff 3 '-r ---Sw * . - V 2 23 14 .2 T r . 5 j; a5 : .2 ^2 22 > -. 1 ii= 21 = 1 E5 =^ = i- "- " r = 5. - -= C = 11s Ii l? B ~ = B2 is B 1 J J iiH! "| l!3 ^ -=- 'o I k1 1 ?t: 5 = 1 S. 5 1s | = n i^ 2 I =' -K E "= -5 2- h 2 .2 e y. t? Cg i u*> r-* co ! 0 = Oil > St 6 cl S 6S0V Z90'0 01 .`0 S'O wi - SI 9_'t O'OS 9S I sn oss 0`ooi 6t'0 O'S 1 _______________ I 'uo: 'U'-ui:w:\- r;n'/pur < JO 91 Of D St Jd 01 -0 6 ujooj suoucjsJo J3j | y St or i3irvo ;n jo joop uiojj ' ij 01 M ft st D n 01 Jl u Jl 9 JI r J[ ot 6 s r f01 JI 0 6'St 6 3utuado ;mujn? jo luojj ui '3j 9-f jt:\oiu3J ) ^1 9 d[ a^nunj 3i{i }0 Jo) J3AQ C St O s Ji s Ji 9 ^1 Sl-6-00'6 SuuiaJo wrujnf jo wojj hi `if 9'f Surjnoj t 'MU ,pQi{h'!U KK'dd,' uoijirod $mi<}MPS uotjrjfdo /* <s;J.wry T.13W W.-imunn iV SOU\H1S33nO.-> 10(1 DtHdSO*MV '1 31*'.L -= =f t J ? J * * ? p 7 `-s 7 S- i* _r --=~ . '-r r~ r - r .z. 1 | P* P 52 S ? x tc 'E = 1 ? 7 0 -?x x " 7r i. ? s c CO X C 1 I = 3 c c * r -x | ry A n A n a lysis o f Dust a n d Fume H a za rd s in a B e rylliu m P lant 377 - f9C0 :ri - - two ffi'C 9i I'O -- oscro ioz*o :oro 6Lvo ezro itio S90'0 S'r_ CO -- -- -- -- -- fI -- 0*9 0Z -- -- COI sw 9*F9 cfr r1 COI ,, 01 u u ?t 1 a 1 9 t c C[ t- toj.'r.iuji jrrr-i-0 n jsnp Jai'ij J3 uijiJiijt jajptls i| , dI dI UJOOJ JO apis JCJ OJ dlUCJ p33CV^[3 di "i}Zldl u|i>{ jo pus aajrqosfp jo apis 01-aj OZ 13 ujiif fo pua adjuLpsipjoaprs 01 13 UJTlf JO 7p3U IUOJJ 3[SuC ,> ic `1J 8 D di dI u|i^ jo pua 33Jcqosip jo apys 01-ij g Zt n or 6 s 9 9 t di f dI Z dI n-oi uiq JO pU3 33JElpStp JO IUOJJ Ut `1J ill UOUEJ^do Jjuunp upif .urjoy [ i =a ./iu ?*' :uo: :u?qdsouijy i 3a rtaejSojJiiU ut jfjot') lutiiiuv^ usifrur mpoqt3M ('K'v) fut}4M?S m!JL uottnod Sutiduipf jo /rpyj 3j4utP$ 30 3a iwiei iN3Ki\iai ho wnmuna iv \oinu\"nsoi i-hj oih3HcKok.lv -{[7 3'ihv_l jojjeJuji spejie-j (-) [dturs )$np Jsdtj JsSutiair uSpij-y' Jj K ZfC - 9 59 I t-9 ~ -- HO'O cOV -- 6Z'Z ~ -- Z'SS -- -- srco -- roco 600*0 -- rso'o 6S0'0 00*0 ^6.I -- - -- C't -- -- -- -- - - f" -- r *o KO 65 -- ro 9*0 -- ro `0 9`0 OZ Of 9 9 st ? OT s C f D jaino UJ Juyjnod D oE^r-oo-tt dI dI qinoiu 33Bumj tuojj *ij J31JB A*[3]Cip3UJUiJ 33-EUjnj jo doi J3A0 '3J QZ ft IT Q JI U1O0J 33CUJOJ 01 AEA\ loop IUOJJ -1J A3f[c jainQ 13 6 di dj di Sutuado aaeujnj ujojj 'ij 8~9 dt di di dl octn-stwi 3'uyuado aasujnj iuojj -jj f Suyjnoj I ( d i 3g (*utui> ~ `SaC ~-------------------------- mn ^rwpjtojjius ut jpjo:') %utj4tur$ tfOCfl3Ul futi<}u/p (Wd) *&* :uo: :uqisotvty nn)vuv 3{4tup$ UOtUSOi "iuililUV^ UOttViido fo ireqj ` a xnv-m 30 30VSH.13 aonio.TTi KnmAaas iv houvsj.x3dxoo isna oitf3Hdsoi\'iv 3iavx . nii A n a lysis o f Dust a n d Fume H a z a rd s in a B e ry lliu m P lant 379 decreased d in in g (in- cu ke -re m o va l p e rio d as in d ic a te d b \ values o f 0.1 10 m g . / n i. ;{ o b ta in e d w ith th e f ilt e r p a p e r s a m p le ! a n d O.Jjdd n ig . in .'1 o b ta in e d w ith tin - cascade im p a c lo r. T h e im p in g e r also show ed th is decrease and also s ig n ific a n tly lo w e r c o n c e n tra tio n s th a n the o lh e i *:2 =w C l = -- j- x * = ?' i SC | 5 I l-l A XT __ 5 ~ = ? -X = " i = =: -- -si X = r J I -.sx T*x ~ s x r X 'z it = 5: r ! - = 5 = r ? --~- ? I -? I2 J= ? *? 4 i l i Jk~ s = ---- " u 1 t s -- .1 i 5 ~s t % ic ~z 2 | s: ~" S2 .1 5 = -2 ~ = ' 'C xrs fi ik2 = is-? .2 = p d = LS S Zf- Z z - = I z c *Mx S" LI -Pi= 7-2 i" ~ 7 TM *= t ^ = HIr ^ v: ? 1: = ? - * - = .si =<- = i- r Et iz .-i k ^ 5 ^2 - = 0-- i %= =? r-- ~ 5 r j 1:1p i: I I J= - _ 1I :M 2 = i8` xx w tc c = `C 22^5d' = S - = -- z-- ^ '-x w 2P I sc -= - = =- 2j -- < III S J *j 5t I 21 1 =I ^= =4i : s - ^. 3 w'si 5- I! I =rr i " xS 2 ^ w x-- ->r-. tC x - Sri4 ; - 2 at 2 =r a -5 11 ~ 1! 4 5 1 - _ > = - = -? - x > I? = = r- z -i x- J: =. I s =- H rwr M ~' r. .5 : I = li 1- ;= T .^ 2 X > ~ = " =1 1 i ? 2 p : 3. X i x --- .1 -= `r 1;*? r. ^ 1 til I -s : 4 I Ik.= = j~ r PC ^ 'E -r .= -- .2 --i 3 2 .= i- S 4 = r- - tC r x= -i 2 x. p c rx -- x ir I p- .z -x > xn r . r s= r r -X -5 ^ tf. " x= ^ " l4 4 I I~ = .= X- .5 Z COT ulfT jo pua ^u'jfq^sip luojj 'J| 3[ 8 ~ SOT C6 I U1H jo >\D3u uiojf 5jBui: .5*. n: 'n vj [ruiJi'\ rr'3 61k ^JO [AJ3g UR fO pU3 33'jL'LjBSrp JO 3piS 03 `tj g 9 uniu'Jsdo 3'ut ? I [r.ia:.v:v ro -Jnp up>j A3[[ U J33IK! LI| a 3'uunod 3U31U ) t`3J J 3JQ J3JJI' .\|33Eip3lUUJ[ 3.n:uJnj = r0 Z itk qinoiu SDr.uin} iulu^ - j} 71 aprjonp |i:lujo^ _t c 09T 'd^a luiiuajo 3BUUJHJ OIOJJ -JJ g~9 8 3'uijnoj UJrujjAisg Z Sk -- if--1 ojooj J3ino Ul 33fUJrij JO JOOp UJOJJ JJ 91 UOUCiddo J33JV z U [ -- XL' I frsid.uy -- t-S'C SS'O |VJ3UI 3g 3'utuaJo 33ujnj jo mojj ur -aj 9- a F (C.VOU133 3^CT) 3'uijnoj 33t'UJn{ [l']3UJ ujnt[[ ij3jj ^SUOJJILU^ muij S2K gimip JO 3d.\2 3i> utuiriAap p_Js -UJO30 kuojDiiu' 3Z1S Ui-ip^y jusuod -IUO? uotjnocl `Huijimi's ou UOl'rjsd() a isv id x\ ,N.oii.igiaxsiu ss\ is 'i'/is-i`nuva ]]|'| :ravj^ In term s o f flu o rid e concentration, how ever, the im p in g e r samples gave h ig h e r v a lu e s th a n those, o b ta in e d w ith th e o th e r m e th o d s . T h e b e ry lliu m d u s t c o n c e n tra tio n s h o w e d a v a ria tio n o f fro m 0 .0 5 0 to 0 .5 2 8 m g ./m .3 un-iin i ~ -i -s g .. - i.. _ _ = 2, S ; I ^ nr ? p .5-1 s i i-r -?-i i ~ i- -5 *s -" ^ 5 I = 35 -5 2 ? -= Jr - -- * 'tr = analytical m ethod. S. r \ i < r P h m n n , P i- p iu t im - iii <>l U ; u h u lu ^ \ . A n -m n - l-.m -rg y 1'i ' ^ v i , U im c r M U lt m - lH - s ir i, U r n - lu s t* r , ', s< w cicM itly s a m p le d h y e ith e r th e cascade im p a c tin ' o r the. filte r p a p e r dust sam pler, h u t the m id g e t im p in g c r gave m ore sa tisla cto ry recoveries fo r soluhie b e ry lliu m fum es. th e y e a rs 1 9 l.'M 9 -l(i. D u r in g 19 U a n d 191-1, th e s u lfa te a n d h c r v lliu m cop[)er processes w ere p a rtic u la rly in vo lve d . F o llo w in g im p ro ve d eondi; tions at this site, the p ro d u c tio n em phasis slu tte d to h e rv lliu in flu o rid e f IT - = Z-5 i r j .2 -- 4 Tf <N QC -O Q_ a. < r u -I , c o u t) c c Oc VJ o C --C 3 E -o _a 2 2 >. uc CQ ZO. *< o >* <D E a CO x. in the lij'lit of the variations in findings betw een anim als am i humans. In this w av, a m uch better u n itv in general o rj'u m /a tiu n van h r obtained. (0 Jl i i<-f, D iv is io n o f M r if ir u l N V iO u v s , A to m ic KtTt;\ f `n > jr t t , l!n iv < - is i( \ o f R o r lir s - to l, Ito i lir s lr i, N o w Vorls. value: ( I ) T hat the to x ic ity varies in genera] w ith the so lu b ility o f the com pound, the more soluble form s show ing the greatest toxicity. By inhalation the soluble form s tend to produce an acute effect and early m orta lity and the insoluble ones, chronic effects and perhaps late m ortality. o03* CT> t- *- *~ ^ * 1 1I eluded uranium , th o riu m , ant) lead, in th a t order o f im portance, A d e fin ite in d ic a tio n does exist th a t p re v e n tiv e m easures such as en- closure and ventilation of hazardous areas w ill act to w a rd reduction of the incidence o f cases o f to xicity. E LU > j) v* U ov. Q. Qi a/> < E2 c 4> O' < Q_ k. U CO 4) a x V LU > "O CN O -C Q "5 a. <0 <e Xc u< 5S -= : - c' -= ir 1|i if Sit J m'**111 mm -2 = .a m=.='= = = ss^? i,Ji -t = " s - = i j^'rz c 1 ^ 1 i! = j I is. fU-I 1 s ! PfSiSpI- 11 = 11 s .1 ^ ^-1 ^ss;l?i= I.' ~~ XJ ^ g ~ - r'" = 5 < -3 = = s = .= = = - ,: --- .ax C a a -= M 4 c ,= --* S o -- 5 'a H H - ? I ^ '- + I -- - 7 c\ Hu tiiii ii.Hs it"ili5! I m\ Rimaj-fc " . s i ti s _ _ " r a >, c- " "3 ' .- ~ = I * ~ s * s. s s r a 5 'i 1 I 11 .s ! I I' = | = ;i *sS ir^ii i ru: hMnhs g 3 I I I g T a E 5 5 ; ; | = I " 1 ,= - S. I f| 5 iSj!|!iiJi]lMfl^Ii1Nj=l ' ^iiMisi|iiii?iiuii^r>= jr ~ _CN w ^-- - ~- sllfl :l . i' : h T- r- - = -3 = '-t1 =ii=:-=>?; Cl~O#i 2~I-2'll~-;;J= .g.;jcsg52;' ia -'3 i~ l=li ii rS Jii*:l4t=l5sll~c b.1s =s l^ lISS j S- r ?li0<w f---=ig - - 5 = ii._ ii_ ' .! J j S3 3 a: - k "X .5 -i 9 = I j *iU 5 ! ikllilUHiUmilm if 1 If ii: r t -1 ii i j i riii mile a =s i?r. i mu 5 2~ Iff! =i i= ?c S If JJIIfillll T a I> .1 V I . S U M M A R Y <H I N I I A U I I D N V X I' I B I M I M S S V IIII z s = = ""1z1 Mltx r- s = -- E= ^ s-*sii=s i z - = a I ^z " - ~ - i A i j i*l:i zU j-i 7 2 r- " .r - i" j "S {. " f !! - _ i' i- 5 -s M s< :- hi + -H-H+l-tH-H^-+:-H-H-H+l--H I ei R H 8^g-gPSP|8Sg ii s ! ac at. at K " ec at " , : s. ; : '; d o tS; Iijiljjtlti ts L 3 552+ " 2 a O 3 3 ; " " ^5 i&ssEsssli-g^ II -- .3 ummnn c :2l Sfe = = = 5 2 SnSZSSSSs Z ft mill s>` "i * s m onths, there was a sm all localized area o f m ild fihrosis w ith slight a d e n o m a to id re a c tio n a n d a fe w d u st e v ils in s id e a ir .spaces c o n ta in in g M ack d u m p s o f dust. T h e reaction was nonspecific it) type. 1 { , K rit, a glassy substance, after being introduced in tra p e rito n o a lly . became lo ca l ized in sm all masses o f necrotic (hist cells surrounded by a zone o f m ono- n flf s i nr -U fl -"s nr =.i -s 5 5 u * pi"i. !i Ml^lllI!!;| li I! j! 1 !1!! H 111 1s 2I ji '< d dd 1 1 2 o -'T* in o iillis , anti tw elve m onths a lte r receiving a total dose ol 500 mg. in a liq u o ts o l 100 m e. g i\ u> u ric w eek a p a rt. I lie rabbits sacrificed one. lo u r, and eight m onths a fte r injection again showed the reaction concentrated in the upper th ird ol the lu n g (fig . 159). \ .M ic ro s c o p ic a lly (H a te H ). these late, reactions e x h ib ite d decreasing in tra tra c h e a l in je c tio n s suggest th a t d ie lluoresucnt p o w d e r is b io lo g ic a lly active when introduced in to the lungs ol experim ental rabbits and gives rise u ltim a te ly to p u lm o n a ry lesions classified as 5 *t-. In addition to the experim ents outlined, others have been com pleted and m any arc s till b e in g c a rrie d on. A great v a rie ty o f c o n d itio n s such as p ie se n t. 1lie large m onoim elear eell response, so p ro m in e n t in the e ig h t m ontlis anim al, was not a conspicuous feature at this late date. Urns, the results ol the series ol in h a la tio n experim ents and also o f the and rats. K u rllie n n o rc , s im ila r tum ors have never been encountered durjut, the injection o f 75 d iffe re n t m inerals in to the ear veins o f rabbits. tum ors usually becom e fu lly established from eight to ten m onths fill -5 2 := E< 5 5 =s. -rs ; e 2E: y. = v: l/? = I1 * 5i = =* r iri k >= 2 IN i; i - = i = 5 I^ i -- > . sj: t4 E~ = - r: ~ 5 = 55 = *= ^ .4 s' J I iS = E - 3 E3~ S= -= f - "r- i5 --= s ~ = -5 ?-== = Xr _~ J " c- Z i .k H" = = 23 -- .; Hi? t H x 7 I i '23| = = : = = > -~ 3 I -5 5| I X = M?= = =s J2 E 2J l2 = C ~ .=- 3 -x _= 3= .= i 2 I1 - 1 z 2 u `M ! TJ Fefil r- c I I j y -Z =5- r i = i -- .= " x .z I ? i '{ 5irz x -- fj 2 8 i ?- S * rJ -= 3- .2 = E 5 -= s = r -2 t JE -- *e .-?-=.= -- S -- ~ E = E| .= ? _c r tx X ~~ 2 t E i = eb -22 = 5y"~- e = -e 2= if |J f *s = i-1- ? =c = ? 2~ -* J r .S y. ___ --" ? - c .2 3 2E -- ? 3' sE ^El 3 _= Z- s- K E i l Jl r ~ fli ill 431|3 I i i .2 ^2 3h 113 E - ? - ..7? 111 ii If! hX .Z " B "5 = ` E~ ax S2 3I i13 "3 2: c i = c 2- -- *5 - > :o E ,ri -m J i- : ^ = " 3 x |c .2 = ^ II I s^ ? 3 - -f .b = 1 5--= 8 E? > N M 11 E= i r ^ ? T e. ; o z = i r- 2 C 9- 2 = " 7. ^ 1 -= s i i i I = s = ii-- _ X !S '5 2 s = E51 si f Li s. 3? s --s I ^ i 1 r 'H i E f-- zS Z 2 :?i = k5 5 '= ic S 1_x I > jz - z: 1 I1 Si I ~ = tE 4: g 7 ^ = _ w = r ---- - = ! | 3 Ui J = = -= 1 i 0 ifj I= 3 I 5s I= 7I`B - 5 jS ill NIJI 1^1 1 2 J?= 5 .^11 in m 1 ; I ihi 4 > If I5. " N. lli111 = s i S I_= ti = =t X -i --" ~ E -E s w N 7= i, i o ^ i -Ht = 'Z -- -- ~ ^ c g > - ~ z 2 ~ = _E ^ *= = = = -u-l S'"-..' i = ^~ - Z2 = !f I 2 -- P^ ~ ; 2. - - c -E ?-_ -?2 Sr h if 3 -4 2 Er = .2 ;1 = =? = E -3 s - = in j jfI M av 1s 3 I o 2- 11 IJ i 1111- f} I .3 I 2.s | ; 1 7- a ! | | * 5 ! J S3 ~x -X .X . 5 Ki" EeI -- ^ J 2 3 1- > - C- - S ~ Ill .= ^: -- f | -I J t 3 i y yE =: - 2 = 22 E 3 >! >. _ *x 5 -3: ='"= .ill: 3 ? 7 I j 115 i ^ i t j f - S i = li 11 1 I L 111L I ^ if2 ? -S i M li H IEll i-- f E = ^ ; jni2| ~ - =.-=-=-= .2 = 2 ; ' 4. 2 j = tx '-Z Er. i- 2 . | .2 ~- -; 2 s in E. Jl: 1 = r i i i 11.13 : 1 I I H? MK "r *Z _, I I V yyJ i =|C IJ * ? = a i 1 -M-" .j i |-S ^__ = J 2 "5 -I! i y iJ = 11 '-- t = 5 C .r -I U ct ,> j |K 2 r = i-is >2 I i= .= ---= -'XT E= i Ii = = 2 i X. J ~ . - J - 2 Z ~5 ^ . a 2 2 = 3= ? i mi .=r . r illxc ^ C - W. ^ I.? i 2 = > r-r 31 !* i .2 X = "E - = =i e 5 i y u H5 = " tu 2 u ^1 2 3X r?- - 2^ ~= 2 | 7 L: > y- 2 2 -- w _= E-' iia b Jil = j 5 .2 i e | b = ~ -Jr. ~. .= S i ~ 5 811 V* % T7 .z; = 2= s~ - --3 w -=i rr 4=? i4 2 ? 4-P =3 ? =I i E I g.1 111! -r-~ i3 = =; ~ * c = : i1 4~ 1 III = s3 X,, ?X 1z- n 3P *Z t^ 41 HE 5 ini3 4c -x! t? 3g ills J 2 * ^c "=r Z ^ =C ? -4 ^ I- _ .-= -x= ^J yz ~ T- 1 112 p t :1 h z-- 3 > 2 z -5 r $1 >. z .iii2 X > '? 11 ? X~ Ps X ze= - g Z 2 - -.== 1 f - .= 3 .2 === 4* -1 .==?;=1 i_ - = =" *S" wc "- `25 = 2 4- 1 f . 2 = = ~ 2 -z ~r = l? i-t? 1J4 1 !!!fis 7 = 1 x" z I nl g z- z - .2 : s>. 2 2 -Sr. ^-= z-= % 51, i1E 4! ? - 51 _z -- : ' ' : _Z= X_z - if i 1" s. - "6-2 ,: S 3 -- =^ =- -- 1112 P = i 2 =: ~ * <-- tilliPB sI .Z = ^ ?s fill.z ~ !I2 5 37 = 2 s~ =1 = 2 -=_ ~ < z: = r T-- 2 54 4 .Sc c 5-5- -- it 2 3. 2 .2 3 r-2 C2 5l imX "Z it 2 .. = 2 =M2 3 !s> ~ i --- > X2 3= M r J-- .= f -3 P f 4E 'r = - S 2 2= 1c 1 4 i- Ms = 54 5 > ? = 2 = = ? =" ; 2 = I - 3=72 .lit' c o n lim iin ^ am i it m ay he that la te r animals- o f the series w ill p e rm it the higher grade. 45 3 S = - .22 J|p Ml i 2 = > --= 2s 3r" s?: ' b_ -z 3 3 i.X , - C- -= -Z=^>r: "==r _-r y -- = | ~x - ^ > = ^ = 3 J Sis MlS s ^ --x r --z = =- =_ C- Z 2= 333 " = "7 1 5= S - illr - ~ " 3 3 .H n == s J 1? 3 t = it "7 - 2= st = ' 2 ' 2 2 '= -- '= -- 2 r 3 = 3 =2I ;P32Z^- I =' t2 >. ? 2 = 3 s 5 i 4 j l i 4 J 3 .2 I T 4 I I = P- =r3 = = = '= 2\ -- 1 P-I'S 5 , niii j T = 2 ?3 == Z f. f X -Z ^ t C = 1,1 -= rx if f _ f 1 I" "2 3-- 7 = - =z X^ Y _ z: oi 7. -- -- "7 B2 3= rX x .= h - 11 34 44 jr J -r <5 5^ 2> rn = f I =c ! f" 4 ?r 3 == = f l-i 4 e1 3 2 .2 ell 4 1L = c? % %. 52 32 1^ -3. 1 .r j: I ti 3- g i 4 I ^- = 2" 4? ; 3 ^ -Z -z --' 7. r = '? X3 Z-- z z X r -- -z ~ i -f ? 1! zz -4 '= X Z> iI it 3 = = 4 4 1J~ 7 P. ^: 5 2 "= If-r c? I: .11 1 X -- ' v z 4 1 tlI t 33 ? X :u p i' l! II5 '* J i o] pp! it ifp n2 = - :l p s 43| 73 i ill H = 3 i g 1 '.n.W IM K T lU C Ml'lTHOPS 5*5 ll i g sH i ^ CCCO^-nC 111 5 12 '< Z . I~ t s s E c^ IIII 3 < coco 3 -s t = > r --- ~ 71 ~ Z. = ^ .2 = f i- =; 1 i 12 :- = .S 1 i = -- Jr '=!! = i -i ^ ? r .=- s, c iy 5 _ .= --* *"' *. \-_ | i 1 2-^ i 1r =I ? s = - ? - 1 - I. !l = s? -c 2 =' c c o r - _c - E ? = ^ -o "8 CN - 2 a. < X E u =- ii i b&%"J j` "- 2 2 ~ I=E _! i 2 " EI 2 r E =? s 11 : j j 2 = -5 i =*= - = i IM JX j, i i ?? E. s J| : H :l -= - r - c == .2 E ? I O* .= = ^ T ri g i j = n e e 2 '? 2 s * % -- - 2 r 2: ~ - 5, S' E %= : 2 _ >. w 2: = 2S=Ef E .k ^ - -E IH *= E ;r. = - :i; 2 2 -i !H= = -- - I -l i j 2 .- 2 : -- ~ ;i Hi= -= _ s * 11 11 JlJif X~2 .2r- ^-- -^=2 ^ L.S = s== Ul tr. - ! if.k t- -. 1 . _k 'E x _ 12 1 r> ~ ?-- r 27 ^ 2 S = = c` 1 ?i . v = t s zI i I | c - ~^ r = -- - i E I= .' .=1 !i i = -5 ?' = = 3 -= = ` 2f i.H = E ._- ru | g ? ? 5 r t: = == : = ?M = = S-c ^- =2 2 5~ 2 til .2 i 2~ iH . Jill Ij " Jl rr " 2 2 11 ? 2 -r ? x j 1 1 7 3 S J 2=2 t-- tsi -i 31 (<i s u m m .u.v W(. t, u l sav t l,;lt c l. r in ia il u.h Ih u Is Ivuvr h e n . w o .k .n l out ),,, ,|(.|,.m , in i,, u b e ry lliu m in a m o u n ts as sm all as 0.5 m ic n )Uram . W h ile liti 5 = y 32a - -- .z c- ?s p r- ^ 1= 3= = 3 ~ ; = :4 3 I I =3 -- it i -1 3 p ^ I= =" 't? r" = - -X = .= P = P 3 P -5 X P I H _z X= if 53 tl li= 5 I3. 4 31 34 M 1 4 M : ' 44 -= 3 3- ---f _ a - 3 .3 ,. 4a = 5L 5 2 2.-- 3 = _~ -- 2a S ^" 3 4--' = 4 i = i ,s 4 i2 " 3 J *5 2 s 3S c g i a .= S "Tt 'Z __ > s 2_ 3XC 3 -S' s rs <C rs 31 C C C C 1?5 - =3:52: z lit - 1 = = S t 1 - = it- 4 z 3 ! I -L c j i s g 2 1 .e IIP_-= p U-it.; 4' .= I ?a ! ! I ^ I = I I ' X S^SS cs ^ V S-. 5 i I - M^l = I *1 1 -11J ^ 4r\i -| r r'i ISM=N.HH ill =.= - = 1' 2 3 5 a ~ ~. - = = 11 : " ^ = 1I 113 3= I 1 = Ui-fliiiil P 3 3 a: = -=r-3 iI 3 3: :? r = 4 " ~ -= ' ; ;. 3 Mil s Si: test..,! in (h r Sntam u' t^ lm r a ln r y h u t was n - n , ,!,,! us n ns n itu l.l.- I.rru us o ol the .Irrp color o f the blank am i lack of sensitivity, a 4 114 5 --y -a ill? i'll3 II Ni i _ --' a 34 ?' = = 3 ac ?3 2 r = S 34 , = " .X 5- 1 -^ ~ z .z = .= = - ;:* 5 11 = R "= "333 . I 3Z: P X _" I1 I 31 - C' > irP r X1 r -? "5 " 3 P - --"I' 5 x jz i 5 >, ^ ~ 5. i 3i I X rj .i! > 3 4 3 .a = 1= .1 .x = rz 2 ^ 3~ Iff I ^ II = c 3 3 i4 1 ~ 3- 3 a ~. a 2 .-a C 3--z _ - .- = 3 ' It- 2 r-- 1 4 p r 11 Z n - _' - - .r X 4 = I 1 ^ 3. ^ `o -- -- - y- P - ~ PP s = ss = _ = P ^ N -_ 3=4 = 2 j- X r - r P . -^ ? 7-- P .3z ? =- 3r " .= . VM =' -= Jr. x T ~' 3 4X3 t: E = 3 = 3- i a n p -X c - ^ ~ - -X- =7 r ___ " >. -- rz " i'Mi _ z. = ^ Xx= = r^ = .x r^ 2 2 *1 > 11 ;: I i- 1 -2 II 1l *"- X S 1 ^~ ~-~r X^ I-- _x 7. i z . *= 2 z3 .-- A| 1^-1 _z "x -- 4 J - 'r r-"s~= ~p 0=r X^^ Xr x -x 111 11 i J -E I- 2 3 _ 14 i 5 11 3 - `J = ^^ zz :- :c .= ? = 2 I- Iz 5 ? " Z -5 -X ~ -I - V- - P s > r r = -= S ~Z JTS .3 4. .= -- = * c s k ~ = = .5 _ > j: - ? - = i s = '=* = 1= ~~ -9 ---= c9 3S T. T. nr & I I J X= _' r- = iJ T?' z I ` 1-- lc r ^ ^ ?a'=i -- - z -- -r xX z zr ~ c =z .= x - xr^ .x E ' - % l * 4 1 1z Z ~ == - i I'- = - rj = 'M- i 11 5 Xz s_ :- _ * 3I l! as X 4 = ~ 1 - I - I 5 - i-s = -5 ^z s =7P 5 -> : ?: X= J* *-= - =- . - j til5 ti - l -=' ' 2> '-3 - X :- if- T(. z ^7 _Z Y X z- 2~ n= :i^ = 5 "_ -- T-; i :- == 5 J = P .. I =2 . = - --_ . x z ~ -C5 ? 9 x .X ! 1 - x .= -- X = i E ~ tr. ~z 7= ^-- s ^ = 9 .- =: -< 3 ? 3 ; 3- r 3< = Z - = Z 5 xx .4 = 5 Z -= I," 3s 9 Xs .= j~ 1 = -J I = p = ! Hi _X i ' = --1 = .X 1 z" 2 b 2I X I ? .a 1rt z t -?'z 1 x X z^ = ? - -z= z fe ? 5 ? -s' ^ X y 2 -= tili ^5- - I c x zz ^ i II 3-- -- ^c - = = .1 P! 5 -Z* 2 -X .2 HiE S. 2= ~J- - X 32 x" = 7. x: Zr r~ - ~ 1i & z: 2 5X. 2 t;. r r ' n | O r c iip a tiiM ia l lK ^ ic n c , M a s s a t lm ,'<*tts D r p a it M ,iss,u lim r t t s . ;\\v;u< \ in i!iiorcsccnc (` w o rk it is v e ry in i[)o rt;m t to ` *C i -X ^i 111- --X .= JT r rx xr ^ -Z :>Ii -- r- - s1 X" = S45 -- Z- Ij r `5 3 - '5 -r. ~: =-- |?- = 5. zy .X >z - s5 --I -s ^ - -s 1 r I i x III1 t-l z5 t I : I s =r .w1 ' c - i 3 I z Z' > f I : z ?. S3 S -2 - I4 IIX. / X i b 2 5 _2 > ? r-- Z -z .5 5 io iH J= "=>. 9= ~5 i 9 - --' = = -- ^ tr. f .2 - Ti > 2\~ 3- 1 HI! t1 =r X >. -X 1 i ^ w x: P x 111. .2 P S T 1 f ~ X l .. 2? -- -z -- -^ x-- =5 '* 'Z=-r?-- 2 = :I i=r- r:-* 9 > ?3 fI . -~ Z -3 _ 2 =r "s ? 5 ; .z 11 Y t9 f = z' zi: -t = 1 iJ x z ~ = X -X x :--== "2 .-r -9 rl- 4 == ' 3J -'I : II s Z x 9i 9it, . zz rs 9 9 - ,yr ^Z -= 9 J- I 9334 x r, t/. r z = 13 43 9z .Z X ^ ~ z: y= iP =k 9 -X 3 ,r > '~z c- s~ r I ~i i g J 41 i =k , 3 4I J I i # -= 3 - > 9 = 4.11 I J z z r~ - !I . ? 1 3 s :C zX r XT ^ ^ "? Z I?- j -- * Xz x xr -9z - --' 1 9 z . .2 ^r 22 x -x = . 3 1 s: .x = 25r, - -z: z~ "5x p" *z z -= " ( ' l u r f of I ,al>oia(< n s . nl ill L a lm i a iit! I ih I i k U it s, As vou art* no lo w . F ig u re K>5 show s p a rt o l a s p e c tro g ra m o f tin* tw o ash sam ples in ju x ta p o s itio n (th e s a ilo r's sp e ctro g ra m is th e n p p n one and the Salem w o rk e r's, th e lo w e r o n e ). T h e elem ents lo m td in b o th ash sam ples are given in table l,X V . T he num bers alongside each clem ent lepieseut relative intensities of the spectral lines and are to he eom paied w ith one V- i ''-- ~r | t u .2 5 1f I= V< z^ -5 !i =r I- ?? w 5* 8 I u: Z^ii ' --c r' ^n ir c^ ^ c > j<i V. _ S' U-------c c Li. 2 h 'J < ^ 2 = X 1 I rv r CN 1 r-- CL % a. < IU i 5 " i >_ _ cCi ^-- N 8Xf = I 4 k T.^; - -7 r7 77 Z2 .5 $ ?-i II iS 22 3^ S r~ - 5 12 ? = ? T= <- , '- ;S 2 ^ iz S 2 z 5 I= I E1 --Z r _ .t 1 SP " K 2? 2 r -2 a c~ * c2 1 ill 112 7 7 sI o *-? - 1 '= P^fCiCS S' -S "* 2z S' ^ 2 `5c *w Hi?i n: 2f _7 iI -s = ?- 2~ = .2 * ; zzx >. c c ^ C -- <~4 c c c > c c ** c c c ' 'X, VJ 2E ^ -- N = W 2 = z= *5 7. *-- >~ <^ .5 2r -SL 2 z z_ != r 5 2 *? t* Z -v 1 .= - ~~ t * - " " = -: - = -2 2 2E sz s : i z in 2 - -= = = ^ ? i 2 5 -l 7 --- 2 = '= 2 r-- C* 5f * -X = * Tj ?.Z 5- xr Z ^ ' -?zX rx ~5=- r 5 ?. I 25 "-- x -- " r y_ z -= =' = 2 "= - -- IS : = ^ S sg s'r = ^ g s; ; sf. ^ j 2 2 22 7 <5iz *x- ~ < -7. - 1115 Si =: = .= "* M i = = 'B k = 1*UmI f 5 II ci z5 5" Z -* It P* ^i n 2 H- ; m! I= Ij 1 S Z Z .2 ; !P -- 7 r- s E- r 11 -z ^ .??_ i2 5 - W- " -= -z rIt - -?= = x 2 oi z J; _i -r* r_ " z -- ~ 2z ^g 2" =? ^ - ~ .2 ^ 5 *5 5 i i ' z. = = =5 ^^ c Z^ X ?. }. i l = 7 ^> n z z z: z z r -- | J T^ 2 Z r i: = -g i .- .= z Zi S - -z ~ -.- s*. -r5r: _ IIinn 5 z -- 5r s = ~ --:= J5 ~ =" .2 _= ^" :s = J= ri 1 5S -2S _ - ii . ^L== P^`c f-i I = Ji | 1Pt ^S. '- -f =- 5 - = i- = Ip i^ A a* =? -- 1M :I r -r -- <-- IJ? .z N = Si 3 |i- * - 5 1 r"r '= & = =H .2 _r '5< X- ? ~= -= 5 = Z Z: I/-" V" sss i/*' X i/*' </-' Is 14 ^5h; I-?-- Z - O < '7. -- flr-=s. --..=2*: r~ x~ : r'~i* k r; - M*:I:t! < - Ss 1 | w -X Ii J- =- = t> L? :F 4 N! "9 J E- w * I i ^ 1I 11 ^e= tQ I i; = Itl 2 '= < i 1 a -53 jS S I0, J S. >. i < :- ~-- <>" fix ' <>flT lu m l, it is also p o ssil.lc tlu .t tlu - fo u r m srs lm d cxposurr to i> rryllin m com pounds. Mill prn 1 ^Is I- : ^ C C C ^ m c ^ intTiH o ' -- < r C :J r ~~ x g " .= .5 T -7 -? i * -s i -5 * = ~. -- ~ = r Z-s ~ > --=- -j=;z= |-^z %lr- S l? ; 0- = SS < c j; SS'S: $^ s. 5 ? 9- ^ ^ ' SS- = S=S ill! s2 ~ - ? s- M > 1 TP it: II C C c -- is- c jn ' i :~ s;Ciciw :' :zh 2^C<3^ss if*| J 11T J- f- J | = I ~ i s g1 k:?: ?*"c i Z I I H1f ! NHi s s. s: ?: > 1 t; * I ? =1 ! s-< ~ -- -- - ~ US = TxT S = ' ^ ~ Z- r cr ' 5!sh- -zz*- r s r- - . =H: . -PH = I i - = ; v - ' 2- : r_ : P i 2 J s ' ...................' ZZ r --. - t~ -t "-==-= = i_ - =f 5 -5 5 i- 2 uni J: - S - S I. - 1 =' ; '= | ? -i 3 5 ? ' * ~ -2 ? _x CS .5 f = 5 | =- = 7 Z = 2 r! 4 z r s -= 5! > .S I I II 4 - 7- s HI IM JI i-5 u! til tii 15 .s - C l = = = f5e. >'c5 t- % = 5t s '11-1 'E II i 1 *1 t 4 ^ r ? s ty x** .->i t I s = 5 p - i ? $ > s 5 f I s "* f ;mii - a -M I s = r^i f i tl t | f ; I = 1 4 '5 J a as-^Jil|jl| 11I l = 11 i I j .11l I 111 I 11 < I f f 4 r? ; -5.-3 E" 7m -- .--r If tf. - It tf -i iI |i z.5 - II ! r | i |j ?" X tf. " ~ ~ -5 = = .* = 2 . r X - C k3 9- ~ c >Xi- i .4 1 i _x ~ ~ ~r = S 2 .; = = === ' ~ .2 if a J 'c t l f. i-I *I ? = i 2^ .= X c fli 4 > "" 1 9 1 - ^i i 1 2ff 2;. ^ r '= t/.J -y - ~ =2 3 c2 iih j; ;i i k I c o tjc c n tra tiii^ = = = ; 1 ? ; s li 5 2X -v if i1 .x . 1 s' - _x- c- ^ = = |2 Cxt --X --Xz x' rz --x^; ?c Ik SI n r. x ti c < ^ '= = ? = ? 4 t S-r. ^ ^i 2 ? 32 ? = l '- % =" 1 iZ J -=?- ^= ^f* I ?t s 7. -- _H *; =s = i I = = r5 S' S' J & 2 j= tf. ~ -tr/:. -- .-xr `H r z == 1 !jIcH= 3 1_ 2= J4 ^~ 1' "kr, 2 .= -- c - II f -s! J " il25?? =?X>isli! 2~ J ji " 2" "x x 5^ ; x hr " 1=1 =? 1 2 -5 = 5I .2 1 ar. % : = =? 42 3= 2 2....1 -= ? c. = 2= -- ?.- ~ J: -- 4 Ik = -- &. | t i rxx -*.= r2 x -5 12 3 V- ~X %o r ? = --5' >^?%,? cV - 2 t -3 = k - 2 2 i`5 x: -X * .x X -=x --- 5^ I >< -S' 1 Mai 5 1" -=' --1 l ^-.x=rn'-x?xr = X X 3 - X w = x = X ZZ x: x; =5 ?I '% _ 2 ? 2 3 T' s ; 7. _E < T/. - < c h e m is tix o r p h \s ic o c lie m is lrv o l b e t \ Iliu m c.m <_pve us m ille d k n o w le d g e .d>nut tin ' p li\s io lo e ic im p lica tio n s. W e m ore than w elcom e such in fo rm a ' t ion. i >h. v n u u A in : \re the re a n v o th e i n tie s lio n s fro m th e flo o i? '= 11 J== f r! II ~ ?f SS | i 11 _5 -- _x c " =i = s i = i = -5 r a= 3.2 c _x ~ ~ S111 ^ = b 1 I = * ^ ~ ^ -9 ~--z --X' Z ~ =F c. - Z l! r i' = f Mlj J i 111 - _ I--I 1 = -- -2 d 9 -H 15 s; 7= c -- J I = .= j S 7 5 S c' - '-">. ^ ~ -3 ~ = ~-3 5a -* ? 5* i! I iHi ? s -: t p ?r I - HI an2 m^ fJ'N r ^ S Z~ 3 ~ . = = m Jz c w I- I H . *" s| i HI * 1 -s I; -Si--" Z i := " .2 = ri = = = CO = 3 ? ^ .2 * * k "3 ~ a S J .3 7 Itfl i *> ^ .'-' `i r tr. xr . 7 == ? lc 11 h ii - c* J5' * rb ~ ~ .i ? " I 11 I ill5!" 2 S - = / .~z. ?T p 2 =7S e r ? s 'g.; -J- i ^ -- _ -= _ -Z = = - r s & - ^ 5 _ ~ 2 = ? i ~ t --_- .z ^ S1 5 c c - = o = = =|^ tf, n is i=x x ^J ? r zf ~ Nil 3 ~ M -'- -I uimi e|. yj I -3 -s- C - r " z _X , r ! >. = = - ci. 1 I .= * .= = si i ^ 1 6z = ;. as = s j f --. E 1^.5 ; tjt *i.ti s =s 2 H*UJ3U0. S "= -Z bl ,, ~k ' ~3 ~ T X- -E i -E 7 -.- ^ s- -p Sy ~ = J. a .= E5 r- f I H =~ = s = i> rn i = 2 = * s ' z N 11 s i f< -s y- =5 X= = c > ^ ~ -r i r. -s ^ = =all! 5 15? 1431' .= , c .c - "= r: 2 -= s 7 -E = .X z __ Xc y ~ --, 7 NU? = - . . .i - 1 = ?; ' y " ? .- O X < -- 2 .-5 s .y si =i MI? -3 i ?NNN N I E .1 j. 5 r v. _ t I M 2 sl rlliJ- s; S 5 s- -- ; i 77 e ~ . := t i ~"~ 5 y. ^ '= "5. 5 c? 2 C ^ > m 5 LS ~ tK T i 2 = =>?.= 1 1 ? 5 r -E ~ E ^^5 2 N7 1 1I N Mil i1 -7 E 5 5 2' =" = = = 7 "y ? =' r: -- -- -- C onclusion o f Sessions on ihe B eryllium P roblem 455 m etal and its oxides;- sim ulates some c lin ic a l findings, alm ost duplicates acute b e ry lliu m p n e u m o n itis, b u t a d m itte d ly fails to a ctu a lly do so. A nd w c can add th a t the w orkers at Saranac Lake have alm ost d u p lica te d the chronic type o f the disease, w ith its classical granulom atous lesion. 3& 1 f! ri 2 2 5 -r !1 K .5 g 2 ' i .C-c >5 s<r.c cc ~ N.fi -I'i 2 = ll II s ~2 r. 11 Sc 1 I f ; % 2 = 'Sc 5 II a r > 3 = *i ~I s ? 5- 5 = 14 tV -z ~G. -2 2 ~ | l* .2 2 -Z r 2 s _= 1 '5 =E 22 S 2. 4' E a 2, o 5-- -- ^ 2 'F 2 -- _f 2 2:5 - V- -= i 4 = r y Z -- ? -- - I -Hs 1 this*. = ; sS - - ~ ? =1 Itli- i ^2- E x p e rim e n ta l w o rk at R ochester, as o f ju lv lo * 1947. d e m o n stra te s clearlv the irrita tiv e and destructive qualities ol most b e rvllim n com pounds; leases som e d o u b t co n ce rn in g the toxic properties o f h e n Iliu m 0 M c tlie .il D u e c to i. C o n u iu l K lo c t lic ( in t n p . im , S. Iic tu -c t.u h . N e w Y m k . f S re O li.ip ln 2, D m -u ssim i. (/'.< /.) V i/i X V) IS) Q h- CXL < Q_ > rU in 0% 1 c o I ! ' "D iv is io n of In d u s tn .il CO VA> o CL < X u VI < > 3 CO o *s v> Q rn \ O n ta rio IV p a rh n rn t ol H c a ltli, T o ro n to , O n ta rio . s S 5 -WSr I ii sex o ra l o l these eases. p a rtic u la rly in Case 5. th e re d b lo o d c o u n t was \h y h . ' ita l c a p a c ity readings, w here tliest* h a \e been lis te d , are o l in te r- ext. In c e rta in o f these cast's th e v ita l c a p a e itv is n o w c o n s id e ra b ly lo w e r tr. . =lf = r- -2 ? ~ ^ II S' .' w "3 '_, iM i y! - O, p -7 s 5 r~ tt :c - 1 S I ^ a J i 5 e,.: !: 111 to t2 \' peculiar, som ew hat r iiy - lik e shadow sue^ostinL'. soifiow hat. c a \itv form alio n on the r i" h t side. It also e xh ib its a sm all pneum othorax. T h e re was eonsideiable discussion as `-y th e nature o f th e c o n d itio n . T uberculosis 5 c le a r. I I , h o w e v e r, th e re is no e le v a tio n o l te m p e ra tu re , p n e u m o n ia is u n lik e ly . "I his film illu s tia te s w h a t o c c a s io n a lly occurs in these eases. V on w ill notiee th e p n e u m o th o ra x and th e e v id e n c e o f flu id . It is of interest that in everv ease u h e ie flu id was noted, it disappeared w ith o u t K iim re 17-1 is Iro tn a in ,m -10 years o l a^e, w h o h a d been tw r n tv - n in r m onths in e.xposuic. lie was first sent to D r. Shaver (or exam ination in | n|v ji) { y because o f d ilfic u ltv in sw allow ing. Spasm o f the esophagus was diagnosed. T he chest ciy^uj^tion was discovered in c id e n t.d b ' th ro u g h i S ?H 1 ^ _ 2 c 2I i ?= s r2 -. tf. ~r. -- -P $ 25 Ji 3 J= = 3 a1 I1 Pi '"ct 2 -- "S>tf t^2r, t=-' 1 ' z - -2 -I -Z " Q = 5 i l 5I1- *0 s. --: " .- = -= ! H = " rz Ifi Pi5 j -z - iu c C 'z ~ =p I .2 | ^E 1 I1 r. J 10 -" 2 to rz S ; s -j- ^ "z c 476 Pneumoconiosis 'I'll!- next tw o fig u re s in d ic a te the. p ro g re ssio n w h ic h has o c c u rre d in a n o th cr case discoxered tit the o rig in a l survey. T he first film was prepared in N ovem ber 1911. T h is em ployee was a young man 25 yeais o f age, w h o had been six and o n e -h a ll years in exposure. O n the basis C linical Aspects of Shaver's Disease 477 The next figure (fig . 1S2) shows his condition in M a y fU lfi. A t preso u t lie is in fa ir c o n d itio n o n ly . H e has lost som e ]0 Ih. in w e ig h t. H e b re a th e s ra th e r ra p id ly a n d his h e a rt ra te is a cce le ra te d . 1Iis v ita l c a p a c ity is 200(1 cc. T h e re are no s trik in g p h ysica l fin d in g s . T h e n o te is h y p e r- 478 Pneumoconiosis the man was liv in g a diagnosis o f tuberculosis b a il been m ade, b u t tubeicnlosis was not found to be present at autopsy. F ig u re J 8 ( is a p h o to g ra p h o f gross sections o f p o rtio n s o f the lu n g fro m the case. You w ill note the irre g u la r areas ol fibrosis, the pigm enta- C lin ica l Aspects o f Shaver's Disease 479 F in n ic 1,S7 shows a m a ssive ly fibrosed area w ith re p la c e m e n t o f the a lve o la r tissue. Scattered p ig m e n t particles and an area show ing a collec- lio n o f sm all round cells should be noted. The patient died from term inal b ro n c h ia l p n e u m o n ia . T h e fib ro u s tissue is n u n -n o d u la r. a** . ... tit .y*"**\ W&y --* Z -r. it & %= 5 = 'c II 5~ . 9 B = ' c M =2 I\A izzz -1 *? ?.%.% I fB : ~ 2 | 1 I X F ig u re hSfi is a h ig h e r p o w e r p re p a ra tio n . It show s th e n a tu ie o l the th ic k e n in g o f the a b e o la r w alls and reveals that these are lined w ith c o llo id a l e p ith e liu m . O ne portion ol the field shows these thickened w alls b e in g invaded by fibrous tissue. disease had been s u b m itte d to D r. G ardner. S h o rtly a fte r he received and exam ined these he began anim al experim ents using stack fu m e and other m aterial obtained from one o f the plants engaged in the process, Since his death it has been diy.'losed that one o f the anim als he inoculated connection w ith the em ployees in one ol these plants. T he film s prepared at that tim e were taken w ith a portable apparatus am i w ere o f poor q n a lity . M ost o f these film s had been destrow -d belore the cond.t.on came to lig h t. A rem aining film on one ol the fatal cases shows shadow m g s tm n g ly su g g e stive o l e a rly disease. A t tin* tim e < th e s u rv e y , h o w e v e r, p r(,v j()lls|v been t | l(. C.,S(1 T h (. e tio lo g y o f ndisease is s ti|] o h seure. T |u T t, ,,as |H. , la ti,,,, as to its cans.-, h o t n o th in g llas been definitely e sta b lish e d except jts re la te .,, to the fu rn a c e fu m e , E x p e rim e n ta l w o rk is n o w b e in g con- ducted in serai places w ith ' c la rify in g the situation. It is hoped g e sth c b u t in no w ay conclusive that a le w of them m ay have suflcrcd causes o f deatli am ong men w ho w orked in the in d u s try arc also sug- have been present previous to the w ar years. The v io u s to 19-12. ]( is tru e th a t w e have* som e X -ra y m a te ria l w h ic h suggests C lin ic a l Aspects o f Shaver's Disease 483 ? + - c i- " I - I= 3 1 i 1 Hi i= Is 1 l .2 s ~o is5 it 11s f 1 -J 1 1 = Ic < S i : | ^ J I I H ?* z i IS 1 U l I I i I !f! J ! i3 1 1 111* %i "= I 1 ^ ; J I iz 0 'I i l1 j? : I 1 = hi?;- b if ^1 % 1 1l 1115 i i= | X. r rz '-= _ H If2 -J iC -- .5 S ^ = f`" s - f 11.4 - tf -- tr, z X = i x 2= S-- = i 1 i= w_i c^ tr. x = s lipf f el % * = s III ? = = >3 cS I I si 2 2 = -S - -2 e ; -2 = 5. f; = P x x. *X 3 r- E 3- > = -2 -x =f z - ll . r- . x-- i2 * i 3 5s = Hi S.2 '5 " -= ie Z '~ = 2 ~ V. t.s -= . = " ^ - 4-- 5i x I :1 1 y -S xS' cz=r 5 -? 3T 7 -r- 5; 1 =g i1 ^2 naX r- -a ? - 5 = - ~~ -- 2 .x 3 =2 i II = " 2 = k 2 5 ? Sl -I4 I 3 Ss -- 1 rf 5 . r* h B - o >. J 2 ?= c-* - - v; 5 i 1 ~ -- V5 r "3 < -- Z = c- = 5 1 5 ^ ~j: 5 ^ s -- -r C~ p S = = n 1 4 ur 5 . x t ^ 113 ' if. r .x ~_ ^ t; = - X ^ .s - = S.J 1 | - -X 1 S | 14 2 'x 5 - 5 - 5 x -z j5 *- ;= - x^ 1 Z J^ i i: % 1 3 5 If; % % = = X .X = z v r.2 ^ . r ilx i .x t .2 2 -- ^ s -- -r i 5z 2 ; -= J i i s' t- 3 y- - -- ' - ;r. ^ =' = - < 'E i .2 c. S l<; d isoas '<^ In closing, J w ish to draw p a rticu la r attention to the radiologic appearances w h ic h co n stitu te the ('a llie s! m anifestations o f this disease. These th a t, in <111( course, these e x p e rim e n ts w ill h e a r fr u it a n d a ffo rd tlu ; a n sw e r. P n e u m o co n io s is I i I 2^ i i z fI p = "c u v- u it it .= I *5 a lx rr IIr ^ if; . *; = J = s' -2 5 ^ I v "ii " ^ ki C VI . .= .2 := CJ - X : s - >= I |- ^' r >-- =- 2 x= = :==? 1. I' I ^ f .1 ill I X X '= " = ii u 'z 5 9-2.= x-- y O r , = PC- = - o i ^ C .SC > | s S ~ j- 4 .z iI z ^4 - -2= 31 -3 1 "- = t \ l 4 .c =p I -X .X - -X i = - E s X iiK S 2 = Sc 2 r 5 lilt = 2. i- = PC 2 C. C ?r- e . . X _= = "- 2 = - X I c - -11 "= tc -- --- ~ 2,, - x -- -r. Z -x ' P 1 220 sc = = - X x - kr-~i " ^ - .= j y'c ~ T .= ^= 2: 'ii v ^c3 ~i E -| HH 4 41 i 11 3 xr' - I-III i $.X x " ^ C 3 = ^2 ^ ; 2 s ^ . k = = 2 = s-c 6 !I i5 S- s i 11 482 in GO o> Os C c = o O tij h u > = tc X * -,: -= ',0 TT O  ..= =S? tf X 2 5 7. * e- 1 - ~2 s 'H -2 c -S2 I i ? 2 * \I ; p - .* i =.r s.- x =I r: ^ a 5 =- --i = *~ * i- -5 Hi "2 K --- ? Is Jr ? _ .= 5 y = c .2 =3 = .2 "f _ S r S v: f -y n - .2 tf. a F2 S -r PI = - = p! p 5 * i, S. r ?. .* r r s g'2 c = r- ' -5 t 2 tr- i cc 2 " c "E-~-" r. ? - 2 4*> ~ '- iS _x ?= ?r 5 3 I I i-P " i r- _ i1 M IKI I. I i. ;=- .- i IK5 ? 2 . l = -5'I ? I = SM if =?S *T- = 2 ~ _ il* 1 P P ? '' i. - > S rT x z x. .= a r = = -= - z * z '"' 1 i2 2 ~c _5 s r- 1^ "~ s f| S i 2- 3I 2~ I "c t/: a = 5, = ;* - C ~ ^" C^ c~ 25 i_ Cr. x~ ~= =Iy d ? I r J5 r Z? i r> >. I 3 -r =i * i = X, c = r1 z ^2 I r. 488 Pneumoconiosis form ol this dust to the lesion producer. W e have done experiments w ith vitreous silica, an amorphous form wo knew to he in the free state and to he practically pore silica. This m aterial produced ordinary, typical s ilic o tic nodules. Thus, it appears that, if silica is at w ork in this disease, </> *0 < X 8. <u (SI 15 o e _c U *o v: ^ S' w .S I i rr 2c: E II 3 = cS P 2 5? S| i"l! itco^sNcid-NC . p <w' S, * 6 iC^-iC^cc-^xxH i n x<-j nc c n d " c c c c c ~2 K5 = ' 3i"l * & ^I! **l\ iNjcc^c-cccdc ' d i s -t' `SSS 3 SPSS'S it-C^ONCCCCC id I < r- k- ii-: i ._ 0 ._ c . S= = ;iV?,,i6A Sc^==05K4 I | _j _! <i- -- N-su^/i^e-.H = = .1 2~ -_ = == 2 ~ -2 .! s = = : tj; ? -- JZ X ^ E ;_ = _ s. -= vr = ; ' ~ ?0 C-, 'E s, * - gt J: " P ?n ss **-. " I 5< I ; =- Pi!' :i'?S^5SS t S >d-rdcdeddc ' 2 jsif S E22C? !g O -h^'CCGCCOC jj fi |sii 'C r-J ~ c 5 -- -- dCr^ ; 5 C r~ -r cc d C c d d d , g CC j!* -- -r d doddCd : Uii c C </* -- , a d, c ocdc ! jl-ll --r - rc-< | -- i/~ ~~ ir--J rj v ---- d ^ d d d deed 52 5f V * A ... ;5|^ 5- 3' P ' J : r- P_ \ d .< y. z.1 :: r 2 - ~ 2E s_ : M .l -- I ? r; * i 2 s; pJ X ~ d g a ~ 2 2 I r , j ri ?# i o ;=P Efs= 2 -i -i i s il C 2 _ I . Z =N 2 = fe 2 = I 'B If | E, ! .a iX I ? ii r ill! = 1 =2 s r --I 2 = " \5Sc - v- 2 " ~ .2 s j; r tc M ~ ,j i E2SgSSrSi328^Kg : Sc ! 8 8Or.-K-iTCiNi^C^'O^CO ; ' S! 2 ~ci; 3^ fcj -ss' 'C~ C~ NC' tNi' ^C-C ^SRgSS8?$g5SS j SS o--i^TO<Ni^oc>~o^'^,'f^'CC i g d /-"s /'-- a VA V_^ v_/ II '|.S. a * _a 11 % i is I n s 5 z z u 9. n IJ 11 l s- = sa s r- p g 5 II s isi s 2 -2 I J5; --I i J ! " v ?= = "5 = ~ i ];? _ c -- His 5 - - = * ~ .? ~ J o t 2 ? 5" ^ . s I fc ^ 2 T o I S 332 = s- 3P2 --D 5 3 '1 'c I rt 3 -S * .2 Z -. s. . t- V n *- !2 -r _= 3 g if E. S J| ^ 'e / '- 3 = x: i = o f -2 y Ct fits too w ell w ith the observed facts. S im ila r lnm os arc encountered in the o p e ra tio n o f silico n and fe rro -silie o n furnaces and also in the practice o f arc w elding. A sam ple o f hm<* ash taken fro m one o f these cases show ed th e same a n a ly s is as d id th e fu m e s, i f th e s o d iu m , p o te - n a n d p h o sp h a te s nor- S haver's D isease; S um m ary 499 I t is e v id e n t th a t syste m a tic research is needed to p ro v id e an a d e q u a te e xp la n a tio n o f the e tio lo g y o f Shaver's disease. In th e m eantim e, how ever, the in d u s try is ta k in g active steps to c o lle c t the fum es and so rem ove the (A 't > J c I .2 X o <N ICO cc a. < X P causative agent from the industry. A lth o u g h there are certain m echanical 5! II zz r: c~ 1 "1 r-- 11 --- .2 =: 7 1l _ = 1 II 15 i - b P -I = 2 -- 2 ^ If Ii . * 2 *r io 7. -- ~ a- ~ *c rz s = rz .r _ *r *i r ic %V J'l 2 .1 I&^ -=r -- l 4. 1 == Hi B ~s -= '7 2 .2 27 " E. c=_ 55 ! M= tr, `5 .= ^T .2 s `7. ti. S %xr- 1.1 1 I- E m i.= - _r .2 2 rr 2 r'- ^ i s s -- s = J: s 4 s 5 . JjI tj 11 =% M -- -3 PP ^ ' = -3 - - 5i -'-z " s sZE c .E ?r ~~ P J 2J ? ~ r^1 -? ? c a. n ==r ?Jf ' 3 ^:= . S r= I 3o s - Z_ c' i = I i i P2 &! 1 % | : ` 5. c-~ Ss =- J ij - ss I = t i I 1 E P- #= p I rz Sf z s t E= I "* ?* _ 2 ^ K -J s * " iI = I5 |j = f, : c ' j - = 5=J: 't 2 1! z *jl ,- jM:_U*=- rM- r1 sslil .. c- 5I -^ i p 4 3 E" ^ - .p 4 5 = i I /&> r n e~ = !- Ep C. = "I !c = J= ~r f1 T' -- tc - -? =z --k |E |4 r. " "? II "c I ff- ~~l _ \= ? = ^ '? II . 1H r- = *s. =.. = - uc ~ C* _ 5E" r ?? Ici 5- > 2 Z S- = & ^ r* F ~ ^- = J= = 2 *Xk ~r. -- =- r ~ : if: J =i -~ * C ^ -/ 2 2 2 ~t r d~ ? "I .2 x=r' - Mt -S 5 I Ii 7. -r , *-- c .d r ^ 'E z v. v - CE .~ = = ? 'c " -g t 5 r- = ^ x =2 ; ~ k~ ~ k. d.'o = B. Z E =P i= = 5 ZI ^t HsH r- ^f 2 s 1 iJ i </> <u (A Q <0 C O to a >3 LU O u oCO cc O < a_ o <4J <0 v> C a oE KJ n co co Q a. < X u "T3 O view points involved in w orkm en's com pensation. I feel certain that a ll o f ns w ill not be in agreem ent, that view s w ill be expressed to w h ic h we cannot subscribe, but I know that each o f us desires those \sith w hom \ve m av disagree to have the o p p o rtu n ity to express th e ir views and th a t 0 M n llik in , S to ckl)iiilC (" a m i W a trrs . B a ltim o iv , M a n k in d . E =HI II' ii t i 1.1 WW- H! li^ ^ . TZ lj lllfj'ii^ii mm*E5 = g-?~cs.2*_ s-i;iisijiJii, =L ? :m?I|? Iliiil f = it C s i - i * ' s r- = " ' .. to Pj 5 >, S ^ ^ i Fr.p " =o =c =- = = -= = N1 H ^ *'4`i I ?- = ^ = = =0.0 2 -5 * Jr ~ > o -- C K -- r I M :i li nt, eii H; Nil 514 Pneumoconiosis him w ith his role in su p p lyin g testim ony in com pensation claim s. The m edical schools are g ra d u a lly increasing th e ir a tte n tio n to the teaching o f in d u s tria l m edicine. Some o f ns w o u ld lik e to see this emphasis in m e d ica l e d u ca tio n pushed w ith greater v ig o r. E ven so, progress is being The Industrial M edical Practitioner's Point o f View 515 d iv id u a l workers deserve consideration fo r com pensation than there are w orkers w ith whose claim fo r such consideration I could not agree. T his 's undoubtedly the situation w ith other physicians in industry, T h e re la tio n s h ip o f tra u m a to disease is o fte n a s tu m b lin g b lo c k in The industrial p ln sicia n m ar b a n 1 been the one w lm was instrm nenlal o iie i.u llv in b rin g in g the case before the com m ission! In m y ow n indusliia l experience I find that there are m ore w orkers I have aided by pn)~ teeliii'j; them from an in d u s tria l hazard and bv recom m ending ihr.t in* m ortem exam ination that he had a lu n g cancer, the cells ol w h ich had nun ed th ro u g h the blood stream to his brain. T ile cancer in tin* new loca- , ' n ( ;l m etastasis) opened a M o o d \ex\srl w h ic h in tu rn p o u re d b lo o d in to ^'e m ans b ra in b iin in ^ about unconsciousness and death. T he com - It i =^ Jz .2 .s' _ ? n rs -rf i - = -= j w H ;j = ! = = .. . ' ~ .*5 b^- - 5 |5 S 3 " 111Jill I i * 1 ^ i iN = _- - z - -- ~ g 3 '--r 4 E " = J E c ' = - - - - = = ^ " M h ! = c I N 1 II i 1 ^ s = -c . = s ;= _= r: rt is o; S` ~ z ~S- 'rz: z - caps m a \ l)C placed at c e rta in jo b s w ith c o m p le te s a fe ty to them selves am i their fe llo w w orkm en. T o r exam ple, lie knows that persons w ith arrested and healed tuberculous lesions in th e ir Innas mar' safely be em ploved at most jobs not in v o lv in n a sianificant exposm e to silica dust. lie know s fro m his experience a n d th a t o f o th e is th a t silicosis is the o n ly physician and furnish the em ployer w ith reports o f the periodic examinutions. T h e im p o rta n t c o n s id e ra tio n is to p ro te c t the o th e r e m p lo y e s against contact w ith a reactivated w o rke r w ith a positive sputum , nccess ita tm e as ends d e te c tio n as possible o f a m ' re a c tiv a tio n , A nother result o f the enlialitened a d m in istra tio n o f our O ccupational i ri s j:s 1 tt i J 1si b 52 iit 2 2 tf > = -P ai i ? ! T " 22 = *_, *3 li '= I11 P- 55 '`c ~ -C r - ? 1 I Jl iT o - 14 % l ~ '2 1 r- = z -.f. 2 -- ,= .= jj c. b = p! = 5 "i r ~ ___ = -- "2 "? \ iZ - -- p 5 -i *1 i. k 5 - 1 .= ? ^ " 3 .2 r i .- = .2 2J2"i = s- 2 e -5 a J. r x -J ~ r- ZE .= The Industrial M edical P ractitioner's Point o f V iew 523 "" c = E s S4 sr. tS'C sr r . `I ? '- 0a 2 Mk 1 r~ sc 2 = " a. 8 a Ik -si s * >. I * % 3 -a .2 i & `o iiii 2l l s4 lI 1* tl j J Jj= = S a s 7 i-- .1=1 1 I1 S- - 22= a = _ ~ t * fn 4=- a, = !.. J ? 2 t -- 75 - cS w = *| 2= &= E- 5f= , .2 e i= i .2 S I I- s t l 1 J HI5II 5 1 ~ / fr, 5 Zr 51 ~3 ? 5* ^ " r - = 2g ?2 = II i -- c -= -= r =* C r. 11 p = WmUtfW1-?' 11 li."rii I g. II 145 . r 1 I I S'? 3~ > - *t > ^ ft .* J * 5 -5 = = s! =2 = i -C t S> z XX 2 I' 4 12 s fill `= == a a- m ic = = -5 T I illlc " |M mi5 c- =-c ~ y.' o SC 11 * i 11 I 2 =_ a- s. 11I1 E 3. ? 2" rr s i1 1 f I 1 - J i 45 _ 2 - = J? " 5 5 = rt = 1 - j; ;ti ** c sc _ lifl Hi 2 -" '-a a -- ^ g j M -s I a aE = gSb '1 i a? 1 s a I! - - - I= - = = = 42 a 1: I !!ia 4Z- a* a= a!r_?~. ^ i S I . - 2 .2 -- U I S -2 - W-- '5 = = - a = %= a a I 1 2 .1 I =2 = ~ ~ '' ..22 -- tssr. a~' y -= ^ ~ = = = -V f - is: ? r. = = `3 .2 = " .2 3 .2 --r la 2 ^= = P1 s ^- r^ .=--: c- - -T II! j i; 11 1 ?.3 S II rs C '- ? = ^ e: - >:' - I5 C = 2 3 y~ = 1= f tf. ~ -- 1 I^-- r7 " --= : It ^ - P" s > r c - =? ;i = ^T -r; - -- ^ E 5 = > t 2 5=iPS ~~ 'h c " c, 7i Ti X Z - xc .2 ii- i 1 = 2 = - -'- aTi- r~ .S ills 2 2 -~ 2 I 1 I1 I x=x I;J I *z. 3 -= J= .2 o = o # ss -- .2 I ? ; 2 I S' 1*1s2 5 z "2 25 5 i - J I 5 1 1 iUl p- s >. K x = iS i s ' = -a := =.= >. I" c Z k r? *5 - ~ - `s C ,r - ~ - s; ; a % lh s S ! I E -iX - n 11-r a -s | J z z a z it. a Z= X - gg Zx -^ H- V o - i; = _ :c Zf. * ~ i1 | | x -- tr A Jz f I-= x E 5- Xr - g J i= ^ 'r -- -- -x _z h e ld lia b le lo r its a ccid e n ta l casualties, th e re s till w as la ckin g the p u b lic o p in io n and p u b lic le a d e rsh ip necessary to aehieye e q u a l s ta tu to ry ic c o e m itio n lo i the in d u s tiia l d isa b le m e n ts th a t a ie caused b y a w ide, v a rie ty o f o c c u p a tio n a l disease hazards. T h e fa st m o c in g c h e m ic a l and (:!i.iiim ;m . New Voik State W m h n e n 's Compensatiun Ho.ml, New V oik C ity, 2 If - .1 o2 5 ;= c I1 -f s _P1i|I! H : H-5 2% (A c :l C1 x 5 = - - -2= 2- t 1Z 55 ^ s IE 3 5 2 2J = "D *S 5 " I = u < S lloC 3 S I1 2 = -5 3 'U -- -jz t 'is 1 1 5in s 1 3co Q 2.35 * = 3; S .s C -2 1 :i = 3 5 I 31 1 X .2 Jr h ~x sEo kj 2 ia. < : sX I ^V 2 > 3| ss 2 3 ? *= < 3 >, 5 2i-- .2- I3 E.P = -X ~ w -x = - -r- J 2 = ;r- r = 3' 3~ 1 H2 2 .2 2 5 0 = * r. 1 E, g tc ll -1 : I ' : I 5 2 2-;-** rt * | i'o __ z * ; ;n c; X ^1- ^ O > Z = P3 Bf -X X -- H a 2P -e i ~ .2 X "X r| li c 2Z ' - - I ' i x. Js -2 111 if 5= 3? .2 jl % ~z r ~ ^ p a* a ' = z P= - ?. Z- S w ill express its o p in io n c o n e e n iin ^ ex p a rte t i's tim o n \'-- as w e s ta y strcn u o u slv d o : we sim p le w a n t to hear th e te stim o n y o f a physician, p re fe ra b ly a q u a lifie d one, ra th e r th a n " y o m " p h ysicia n and i'*y p h y s ic ia n -- then w e w ill c e ita in ly be in a m u ch b e tte r p o sitio n to ecaluate th e te s tim o n y a n d to have a c le a r re c o rd o f w h a t <mes on. JS "5 o 5= 2= !| I q' rt x3 1 III t s : ^ 2 J 1 El.?' | XI si 2 i3 | 1 J ^ 1 r|i " " J .U O rt T= C >, 2 5 3 - c ^:- 2 IS3 5= I 32 p c J _ 5 3- ~ S- ~ -5 55 = c r =2 S I2 35 ci tf, 2 ~ I M 31 3 3 I ^^ = 3 IC C- - 5% 2T ?n B 1 '= - I 1 ^ i .2 2 ft 2 3 g|-P P 5 - -= = . 2-~ J~ ~ c: b i I II 5 -3 s- ^a ^*5= 3 '2 ~ = 2 3 ! % 3 1^ 1* fJ 1sc 22 S P i 2 = 3 I 2I ? ^ ft = 4 i I ft ill^ rX i?> -- II 2 I !- is | $ 2 ""ll X .- PT ? J.X S I J Ht/. i:3 I; _ I 52-2 55 u- -- - 5 i: J zhZ !J i I -r! : ,_ ? I J ifi" iHl I" 1 " 2 !;= ?i ^i "i71 I tc i r IP 3 I 512 'iC = Tt Z_ I sib= cs x - _i - - c tc -- = = .2 '= a 3 S- r- 2Z CC -.=3 3 3- ?? = 2 1 b " a_ r? y = 2 3izXlli'Mi 2 3 -= JX *- 5w --T - . p .2 !s' -? X= -= = ?k ? 5 ~ ^X ^ ~ -5 tr. *III.-S..is. -ft -= p x Z Z. '3: P' ~X -S -3 s' -- s - x -- ~ .= 2^.5 K _ = 1= i r j= ~ 2= _T ~_ s :-2 ,| .J 3 ~ S: =- 3- - =" Z 2 2 5iiS 111:1 i2 3 3 tt. _2 2 because patient cart' M illers h u m inaccurate diagnosis, w h ile at the same tim e fe llo w w orkers and th e ir em ployers continue unaw are o f the seriousness o f an id e n tilia b le in d u s tria l hazard. It m ust be a considerable cost. hoth in avoidable hum an su ffe rin g and in dollar^. 1 seems to be u n p re d ic ta b le . I' u n c tio u a l e flc c ts m a y v a iy so w id e ly am onw w o ik e rs w h o h a \e been s u b je c te d to lik e e.sposure, a n d even as to w o ik e rs f whose \- r a \ pictures reveal com parable lu n ^ involvem ent, that deter- | m iiia lio n of the p ro p e r basis to r e \a lu a tin e and e q u ita b ly com pensating J. r. k a 2 I xN> n r. If E. " 11 ^5 s= t a-- uC t Ii . > 1= r' ni z--~ 531 .2 = -p r r- EL ?J P- 8 - -f "s .== =2-2 c 'c I1 "ill! I5S=b g r x = 1.i!rl sill!fjl 5~ = Jg i r: -* t1 Sc o^ -X 5 I s = " 1 X = r' S J3 | r-p *: "3 g J j g .2 1 f I ~ kC ig 1 il ?S |i M 5 ilsss ~ 111 ^ B = s -= i^ir 1 s i f. ^ O--` '5_ * ;# ~ ; g <i SC -' wT c Cc ^ * 2V S > =s l1 mi?:. !1 Hi 5 SII- := 2 b y i s I j .r - = :- j h :l 2 I s if - " s - I ~2 'o I J I s '2 r; J 1 5 = 5 "c 1 5 ui = w = *5 . ;= c = "3 *r -- -5 t/. X .2 I =* Z b *s r- c. -5 c *5 * ~= Xt - 'i IIi 5 -? =J * s 1 2 1 = ~ 44 44 5 -= sL 2 ~ =S ,* c = | "5 ? 7 - =i = = s ? = J '4 | . | "l '= ? M z -" = .2 "1 a i! = 2 J= = 6 1 536 . Pneum oconiosis make it expensive for tint em ployer who intends to take unwarranted advantage o f physical examinations, either befnic or during employment. W lia t is the d o cto r's fu n c tio n in connection w ith in d u stria l disease? 11 he is going to ho able to give in te llig e n t reports and testim ony as to View points of W orkm en's Com pensation A dm inistration 537 w itli silicosis, we think, should he kept at w ork, provided they are able to continue at w ork w h ic h they are able to do-- provided a safe environincut can be afforded. W e believe th a t persons w ith first and second stage silicosis should usually continue in em ploym ent, first, because the il I' 1 5 Jt i " J 1 13 5 kg = a 25 > 3 5 1 - So 5 =1 C- 1 l ~ ICS - 2 - s => ~ s ^ ~^rj k1rJ1 *1 >, w Cj iJiB. rr11 Cx c V P e g jjl eS.SC O -- sj 1 -= 5 s' &JD .X! :i -I S g = s' t C 4_, IU HI 5 I = 1j ! = s o =- et * 2 .2 "C 3I *" iu s. 'c J I J ? j- fe ,, i ~ iEx i5i " = t 5. 2 J' J3 ~ I 11 s o -g r- >, r. "5 lit = 22 .2 jk j5 -2 f; o % IS P' 5 c-- II s'J ~" I2 .2 C II 2" - J I= c =>i >= =2 k^ Tc - ^ 5-3 im2 Mir riiS ~3 I 1 r M- -3 == I s!l J f X _ .= = > J 5 k .2 -1 I f.2 3 'l'l\ z .J ? = O . E s= s .= ' 5 ^ .1 1 I .- r5 J= = =, = > | 4 = | = i c 1 = Z 7. I= i -S cr -k r = j S- ~l 5 -~ L J; ? 3 ~ -- 11 = !J - .2 i I -r ; S t - :^ * so 5c Cf ~ 5 - e i= : 25 ; ? -2 a s .M = 'I ii .2 " - 1 I 1l sji 11! | rj ~; . X X s| = B =- =t 5Ij 7 '~ t, -- "1 k _ -5 = iri E >- i- 'z7 S| I %5 .2 _ .= $ 5 - j :5 = .2 . t=' --il= |p - X" r = x .? >t ^ -5 ." = 5 5o - .=- -= . =2 k = s =- 2 = -r z l:c _2 - = =c 2_ if if i H. i -5 s _ i 2 -= k X X 7. 2 1 .2 1! ~ : K = 5 k .2 --tC ^? 2 X X ~ -- xZ cc Z 1J X X .X -X k k? -.o2 3~ = 'Z = :f ? 1 .= -2 Mi 3 W ic I =L 5 B iL ? ^ 1tS'-p E= ,, g ri "= 5 ~ S-T s '= -- *= 3 'J ^ J: 5 x - ; = 2 = = -3 3 ii ~ - - k = < k - = c -- 11 i- ~l s- s - = 3 S' t 2 " = == J 3 k'-s "P 5 ^ 3"f~" =X i- Ui *> -I - c^ ^ = tc ^ ill g^ = 2 k X-- 5p is 'E 3 "5 C. k li 3 .= C -2 ~ "i % = =i-l'. r. = 1 ~ ^ 2 2 cx a. >. 3 .vr -e - - - e E = _x Oc ^ __ .2 _ - 2 - J -7 "Xt S = ' =c "2 2 .= P ii li ^2 =5 CLu ~ 11 r. -2 C- " i: - x = 5 fI > kk -2 t '-r w %^ ~ Z 1 _ = 5 - thus t.m y in g out tin m ost im p o rta n t objective ol all the saving <>l lih and lim b and tin pi< \ i ntion ol liiin i.in s n lle iin g and disliess. One subject w h ich we believe is deserving o f especial attention is that ot a finding ol p a rtia l d is a b ility in a ease vvlieie tin- em ployee is able to c o n ti"",. at w ork. Tin's is sometimes know n as m edical d is a b ility . P ris o n s \e a is. and even thereafter the Board of Commissioners mav accept a claim for medical expenses if tlie v find some reason to ju stify the decision. 'I'he two main ,,nexlions in our province are: (1 ) prevention of the disease, and (2 ) evaluation o f the degree o f d is a b ility . W e must agree tll:lt u ,. n l,,e h in the treahnent; we are still a w a itin g 'th e o s lin i' p ro b le m , w h e n one sees tuberculosis w ith o u t mix' dem onstrable silicosis in a w o rk e r w h o is p o te n tia lly exposed to some decree of silica dust, I'd lik e to kn o w h o w those cases are handled. Let s assume the piesence o f tuberculosis in a short-term w orker, sav a w o ik e i in a lo tin d n o r in some occupation w hore he has a d e fin ite but lim ite d exposure to and no w o rke r could afford to accept em ploym ent from any b u t the most fin a n cia lly strong em ployers. Such a result w o u ld be u tte rly c rip p lin g to our entire economy. T o the extent that onr com pensation law s play a v ita l p a rt in our x? C- c % lI J2 T* = 3: n V X o o a * CO u Cl. c < X u Is 2 x ?S|? ~r X 2 ^ i% 11 >. '= B " I1 i* = >: j iz 2 E I rz i Ix 8 SI : I = O S -= s. = -1;-- = -r - 02 Sf S 5 s, f : ?' =s>=M S' f ^ r \| ~ c- 8 lx " _ 5 S v. = Sc - _E ^3 r -X ? ill II I t5 --2 *2"3 I # i = J = - * J " S E.E " 5 5 " ~ 2 r - S ^T 5 X T~" Cb 2;=y. 5:* -- - ? - = r- C = "2 "ir -r X ~ - x "i I 2 E C-- r X^J j^2 s : = ;I1 i -5 " 3 tc I l. y. _ B s 1- C! b Iffi " 2 =, ? = c T - i- j 1 cs c "i .1 Is i I5S| = Z s J: ' - c3 x .ir I z ^ '2 -? > 7. = Z% S - 0 !'" E 2 U .= = 2 3: -. =! 111 x ~ --^ x S --- ? := s : 1t = 0 r 4 _ 3 X .x 11_= _E x_ >. = = ^ j_ zrX < =l l _2 X r II -1' iv ^ - Tx Z c 5- 5 h = - >. X = -h fy " -- tr. -x 2- x * .x 2 = X -Jj - l 7. ~ ^ = X r- - r tC = =E f; ~ c_ 2 s ~ = r- = ^ 2 = c- -- ^ 7 y. ~ I Y- J. r x = x 2 -~ rx =^ = _2 : r. ~x x-r* _ r - -X 2 11 4.z 2 T r- s I 1 f l t% 3 - = .5 F -x z x *= 7. r; s^w~ -r / . ? 2 r xr y-- f 1 ? I - ^?z 2- Z _ x= -J 5 l y; X X r :i 1 r -X I fii a 1!=4l 3 JS = *3 2 *s . 18 iliiifft^5 iini" ~ T c/: ill*J- 2 ,= -Ms 11 ::| E .* M If " .2s I " C= _rT 77 ' s" Z ti E^ = tc k,. > Z M " B t c. ? i - r -j- ~ --^ e"- > s 7 ^ .. -2 - jk _ ;7 ~r -5 * -= ~i = 7- 24 tr. = It vrr '~ - c ^ i T'- tr. ci - Ms 111o ^ !I -2 2 --- c - - 2 *7 -C i -I I i illU >N C= 2 s ~ .= I r == " ^ -sa * "I rt - 1 "= = - ~- -TtEc -- ~ z - tr. -- -il s % ?: Ml 11 2 tr, -- y :j = 7 '2 c-- -S .2 = I I 2 ^ Hi l! ri= a ^ in irl ^ Ec | 1 i.' -2 - r ? j'- k 2 = >: z 2= r- ~ 5 i1 HI 2i ; 11 I" Cl > -2 2 3 ^ o J2 -= - -? _ < s r | c yc _= ~ U 1~- ^2 2 5 7 E ? 1 1 2 Tt = 2 s --s ^ 2-5-2' 2 EEr' H T - ~L w ~ -- r 2iD r- -2 _2 ~f | l/L -- >.' 2 C- - !i i 2 _i .- = 2 ^ ~Z -- _ tf, ? r. -7 ,__ ___ r = 1 - ; "5 jg - 2 2 '= 7 3 E2 2 -2 x : I | =2 22 : tr. _2 ^ E; = - _ -- .r c .y z* rz r 7 .2 ~ = 5 l i -= :q c_ "3 1-0 'if. 11 ~ it "1 2 - 'c _2 .-- .w -- .2 -= r = ' > -^ s2 2 M 1 =- .z o lu 11f II ! I1 M = t =- tx =H i s = 2 -- tx - rj -- ^2 J2 fr. g 2f, < -~ 5 -S I .- y x. -~ 's '= -== - z 5 7. 2 ^ .2 J -5 g i -r _E -- -- zz C- c- i= i ||1 7 'Ml ii : =^ j5 ~ z = --y - 2^ ? -" ix '7. - 2 S .2 2 = .2 C= Z rz ^ ~ r* ? -2 -c = -i = ~Z U "~Z /-< 5? ? ri - " 2 ~~ r. 7" z r. r .2 r. 3 -H 'c * * 1 I -3 II =* -- ci Ji* --" .2 to T- *9 increasing :iiilo m .itit-.ill\` as (lie passage o f (im e and (he p e rio d o f expnsnic u n d e r the n e w law le n g th e n s. T hese in c re m e n ts m a y a tta c h m o n th ly , as in New York, or thee m ay he anim al or at other periods, hnt evenlnalh the benefits reach the fu ll lim it ol the law . T h is t\ pe o f la w has sometimes been re fe ire d to as th e " s lid in g scale o f b e n e fits " o r th e " e sca la to r clause. w h a t am i h o w m uch? W e cannot com pensate them fo r loss o f earnings, fo r they .have suffered no such loss; nor can w e com pensate them fo r in a b ility to g e l jobs, fo r th e y have jo b s w h e n w o rk is a v a ila b le . T h e ir s k ill, ],o rn ()f V(,.1]s ()| e xp e rie n ce , has been fo u n d in p ra c tic e to offset in m any instances any supposed tiiic iu p lo v a b ility due to physical im p a ir- 548 Pneumoconiosis in fill. A n d unless they m ake c la im lo r com pensation and are physically exam ined, an em ployer does not k n o w o f the existence o f any decree o f fib ro s is in th e ir lu n g s , w h e th e r p a itia lly d is a b lin g o r not. It is c e rta in in sonic trades that tin- w orkers p re fe r not to know th a t they have a m ild The Insurance V iew point 549 unfortunate total d isa b ility victim . Is it to be supposed that bis lo t in life >s th e re b y b e tte re d th ro u g h the. a w a rd in g o f c o m p e n s a tio n fo r p a rtia l disability? H is only chance of escape from a com plete breakup w ould be to change bis occupation to one in w b ie b th e re is no dust, lin t w ill lie do rr- 5 ? . 0 52 I: I 1I II 1 r1 a oJ E j-. cS r* k z. c v- tc tc "S = t" k 1 % =^ s c e rta in ly that he w ill continue under p a rtia l d is a b ility u n til total disa b ility o r d e a th occurs. A m i in such -a ease to ta l d is a b ility w ill n o t b e lo n g in fo llo w in g the p a rtia l d is a b ility , fo r once the w o rk e r is o llic ia llv c e d ified as a s ilic o tic his d a \s w ill be num bered in his trade, and w hen In' can no longer get em ploym ent in bis tia d e , he w ill <|tiichlv becom e an w o ik in a dusty occupation operates to bar him or bis dependents from fu rth e r com pensation in the event o f total d is a b ility oi death fo llo w in g such re tu rn to w ork. In some states a w o rk e r com pensated fo r p a rtia l " ]d is a b ility m a y be p e n n itte d to le tu in to bis fo n u e i e m p lo y m e n t Onl\ ` ' " i d 'e r o f b o th e r com pensation re s u ltin g fro m such disease. -^^ r ^ = -5 3 "= 2 =2 -- X T -tr c l - "t = c 2- c *23 iJi = ^ 5 r- 5 t .25 3 T -= . 35 = = a* c= -" o _= I 1 5 -5 S' r.? 2- -- - ~ ~ >-,2 -' r: 5. 2 C = ' 5 gr- 2 ^ = = ""* -^Sj8 5 == H!_ - e rt ; ^ 3- ^ 22 a, c 11 " ~i 2 s -- r~ s - --2 ^_i 5. -- : r1 2I --S 2 ~i --2 62c20o2ii_i >: r S ?=i 11 - r--* . .2 f *S,2 |; ^3 2 2 j o 2 K2 t .- ?= i * Ir J 2-3*2 * 1=1 2-I > > to ?:== .= ^3 ^== =11 r.> 2 i2 Xr t4 >' - -= i: _x ^ to (lie cstim aU 'd cost ol now mca.smv.s Im srcl upon the e stcn siv,' statistic-s d e riv e d tro m the operation o f the la w in all states. T he m a tte r o f p n b lie p o lic y in v o b e d in the enactm ent o f any such law s is th e re s p o n s ib ility o f the Legislatures, inform ed In (he view s o f labor and m anagem ent, am i In^-the responsible suggestions o f the a d m in istra tive authorities. Insurance i = - --i -- c 3 x == 2 . = ~ t: rt -3 - Js 2 = 2 = IiUU ?1 I "3 w ? 2 .2 '= ^ c-- 2 23 = =- I z g ~ ^ C"'r1 T ~ C -| : 2. " r Sr. 2 sc 35 2 ?* ?> ^ 1 4 5- 1 I 1 -= c 3 >'.2 i: ^ ~ ^ i ' > - 2 2 If ir* 3 > = J s| = 5 I 5 -== ^i;-S=r- z 2 Z si = Si sH .~~ r: 1C-, 11 f r 1 ia-3 C ^ 2 *e Mc '= - t| 1I if1I a! - = ~ 2 1 " E jz + t ! !JI i 11^ S| ' 5J X --3 ? 3 - 1 If r " ^3 's i * 3 0 1 s o I I rt v J.S ~V X> rl t" the problem s o f p v in g eonipensation benefits to one w ho m ay be only p a ilia lly disabled In reason ol it. As M r. Saver has m entioned in his rem arks, the leeislatnre o f this state, in p ro v id in g ft.r eom pensalim i fo r disabled persons b y reason of * T u rle r and Hi-.s.-ll.-, ( .m ael. I 'liia Mutual lii-.in.m o' .. .....pain, t'h r.i. \ TM s> 10 i C 2 2i1 I= S 5S =ii i = I 2s B s. g i ? c' 2 si i v-= ~ c 2 SC o " *"= - = ^hI 2 X .,, = - ~ r&- j: -c rX pS 1 1^ s' K c "u r- 5 P2? = x . s = z ^ jp;i ~ ^ _ ;* 2 y jz o > ' zz z =2 = % `M j 3 2 -5 = = r, -- -s ^ t 1= 1 -5! & 2 i J 5 t ^= | ' Ml Sl .2 2 S 57 c l 1 == 2 < ? !> 2 pHI _2 22?s X~ 2 ~| ; 12 = rz - . .2 1 _ ._ . - ~2 1 L> 2 s' x = P ~r - -- -- S ~ 2 2 - ., = *r = r? s .5 .1 i 1 x 1 = - -- xr 11^ w- 3 .* g .2 5 H - -= . " f = r _^ 2 s t srM'f * J =~ = " c y 2 X. 1 t s. 2 27 rz= nh a y ~=2 % C 52 .= - 2 > -5 Y r* x:?* g 5 1 b= .2 P I1 's II 11 5 -2 iTM - ~ h~ % ~ l _ 2 z jz = t' 7- * i= y - ills r f= = 5 $ ~. =Y" i- s = I j ij - - - z 4 ityi " '- -= t l` 2z 5 '* ^? r- ^ H s .= ra. 2| == r5 I2 ~ y= 22 2 y. - -r, I I .1 2 > 5 2 --= 2- r: - ^ = w^ S =r 252 -o . X-- Zp ^? > ^5 sc -5 2 = = = u-> * hs ft) co Cl. < X u 558 Pneumoconiosis d ia l properly created there should he no constitutional objection to die existence o f such Hoards. W ith o u t specific provision, a m b ig u ity may exist unless the law imposes some tim e lim it w ith in w hich disablem ent or death must occur. I f this In Schneiders second edition on Com pensation Law. lie stated: Statistics show that a p p io xim a te lv dOV o f the in d u stria l accidents using d isa b ility are due neither to the fault of tin* em ployer nor the 0 P re sid e n t. St. Joseph L e a d O 'm p a m , N e w Y o rk , N e w Y o rk ; C h a irm a n am ! T re a se r, rm lu s ti ia ! It\<ie'` [r o u iu la tio n o f A m e rie a . P itts fm rjd i, P e n n s th a n /a . 95 z r- 5 r- W- 2 Co- J 2 tie- I64 cS $10.53 1 .7 4 j I K g|! : 1 2 " - -^J HI 3^ I = ^ ~ I 1 I Ic~ j: ru 5 f -~3=2-oi? I^M f I fitful iHi lsfa %Zz it ? I = 1M jii'li ^ s . - = - ~-g $J| |l* : i J-- I ~~ j .1 j * | ? ? .2 - rf --~ rt \r. ,, - -x -- a ^ -= r2i a 2 5! o s 11 .!! 5, % ~tJI rrf! HI I iJl| I it if li I Jr I := Js ? 1 i i si 14 SE - .. ju n 57 g S c 3^i=ir s 54 I 87 ~ ; c -- 5 = S n rf S! ~ 5 c- -a - - s s J? >s 3 -f K .2 7 7 -- ." cs iiiJiijimi 77 sr = = ~B = S 1im _33 --x c=, ~- ~C 2 _ ~ = ^ yf = 1I 5" ~X *7 _ .1 Z C ~ 'u ^ ^- r- ? 2 ^ *3 " -M M J=s 2 " s ; - = - ^ tc-- _ 5 _ ~ ~ 7 * - 77= - IIISi N|M'Hsi;1 ii c -- 7 S> 7 Si it- O 5 ~ ^ = 7 ~ ~ = # 5 - 7 = -5 7 - `*1II!J = =! ?7J *-- rr I S g-r *. eL - -3 = - =' -S r a t 5r- 77 S=7 ' i>*- ---^- = l 7- ,, ~--7 77 c- --~ S= 7 2 ,, X J? a = 37:* -_. 7- i _-s- s7 --7 7 5i ^-- ^ X .,' = -s ~ 'x 2 ^ 5b Msg. M 9NNMQ AA A := rz pS * ~ A > A ~ .= 5 = _= | = | 'g ~ b r ? f a ~ g '3 r f i .=. a g a .= .11 g- -- .JZ "* Ct -- :/* EP ~ ^ g i 7 = c iJ|::-= 5 I 1 :s - = 1 i J ~ > =r ^ 's 5 -2 --.< tzo i I'%. kl hi- 1 II II : S U ! .'= = A T~ t* - r =--.ti *rr> .=~i *:* !-- rt --- . > !s^ i b A' = =- - -5 ~ ~ '= > ^^" " = -= ._ i= .2 -' = =' S jj = b: 5c S s~ 5 .2 '- -- ~ ^ = i: - '-- -- c= = -= i 5 A= C Lr i .= g s ~ ft A =i^'f A to ^ to - r- t/. -- r = it 2 = m "c % 1I c == .J I1 1 -3 5 . : C - ^ |0 A r -- ._. 2 ' gi a J r 11! 111 := *= s:' - u r =< E s!I ! I g I it i "r 5 I. < " ' -- g = g 2 S t- I i ; I ; |1 ^;?ir?n = ? ?. i i 1 i A -3 ? ^ --t : : ^ : ; ; 3 i sm^ = = * I .= ,. 5= s- g| ?f &, ~ il ' - =- 1rr 3 L a ? 5 I 3 sir = . Oo' f CM^ i,,l~JJ~Jrt Jr- fn ? -3 J'T' --- "3 __ .a = ? Si'5 J|! = = lg*s"tsj IMI ^ ^^-`1 loSgfe I n'h't'ss j: p == - t w z ~ "2o i 'ZV *3 5^ Ji | = S|-, ; ._r ? --> i; Z_ o ^ -. J= ^ .1 - I *' s 4 I 4 ^ - = a :. 2 5 ' .2 - .a -2 ! ? r H = l| ji?i2:. = ;: ' ^3I 6 = si=:|j;hic -^ x ; X 3 x si CO olo 5 = C- .= 5 ^ = SJog-5 Z _ ~ l> ~ ^ x^ ^ Js = I- T 3T= l x: St i ? o r^ ~x ~ ? _^ i --- 2 * rz X2 *5 r= = .S -' = 2~ =y S.4 S -* ~ 2" " I I t/, ~ Q = = - 2 r: T- x X i1 2r 1lft" s Iis ~ ~ - ?T ~ 5 i 1 * - -E 2 'J = * *2 1! = .11 I p .: ^S * *= gH i/ ! ~ 4B ~ j? T ~ ? y -7 - `H | JE x -r: cr: p . r- ^ x " 2 ' - i 5 2 `c = ~ = r ., 11 ii M 'c ' SI I IJ I y~ tr. ? Z '7 E ?. E z < rsi ti ft - = 2 5 ? -5 ?tt S; 3- ZL E Z ^ ^ z o l Z % I.Z = I "'is?*"' -- >- g' ~> ^ tl 1 ^ i ^: ~z . : : Sc CS III? % i i- 1 i ~P ? "- --I _= ~ ^I = TJ _- -- 3 s -- 5 -" o 5 c ^ = :- r tt - .1 i 5 *y- . i z-i _-= = iI? 1 i 3*3 i - ~~ ^^- 3 2 11 =* = s1S ? * = ~ =3 3- ? > - ? i -- | x 3-=. E If s l|3l s S S-1 u -I 3 5 >. 3 * 3'P | I x t' = g =1 3 =^ ~ 3 % .9 H - i Jt 4 Mli I .2 o I M5 3-2 =M ? 53 .a t; f 3 _ _ s = 3 | l* t 1 5 I 1 S- 5 r> ^ -5 - - lili-- = r " V 5 5Z *= 2 - 3 " 3 3" = = = - .= Q c s ,_ -- .y ~ 3 " 3 * y I f i= 31 1 il.s.. ' ~ 3 =_ c ^ ^ " C' _ - " = .3 1 -= * 5 ^a%% s |o I L | - ? I 3 .: : 1== X 'C -* > - c<:' = 521s ^ =." S -,, = :~ -- ts -- -- . s = . - y -j ~ " s. 35 -3 . = j to 2 *i S == .5 t % s ?^ S333 X 3 = - = ?< ' 3 s = ^3 X = J3 J I 5 " 3 ?0 ^ " v $ ~ 2 n^> "- o z - s = - -5 SX 33 2H 3 i 1 f -3 '=i ^ ^?- %2 =c S C-' - - v: 2 t = ^3 ^ 3 =- - s o 23 i 5) I I I X 5 So, th r rm p h a sis is on p o s itiv r in d u s tria l h ra lth . T h r F oundation, th ro u g h (h r assistanm ol D r. O. S appington, lias com pleted a tn y ra r survey o f iiu h is tria l health fa cilitie s. A lm ost tin tv hundred plants w ere c o w rrd in this study, w h irh shows, am ong other things, (hat most com panies, o r most plants, now h a w some m dustrial health service. M edical Referee's Point o f View 575 o p in io n o f (he hum an m achine was that it was unnecessarily com plicated. 1 th in k th e p a n e l d o c to r c o u ld o fte n shave* th is v ie w , fo r th e c o m p le x itie s o f (he m aterial w ith w hich he has to deal arc great indeed. The doctor is som etim es fo rc e d to fo rm an o p in io n u p o n w h a t an e n g in e e r w o u ld co co O' UJ *- Q_ < X if am t C> -- f= s S'-~ c. = _ -- - - to ' " - 5 = -5= -- L, '-- ~ r'. ~ r-t- = !U! = l" --- ?O 7z1 2c; C -- l-. -- - - - - ^ = - s 1111 ?:! H = arrange a pum p w hich d e live re d the flu id u n d e r a fixed ra th e r than an in te rm ille n l pressure. A m i w h e n it cam e to locom otion lie said th a t any engineer w o u ld n a tu ra lly e m p lo y w heels instead o f liv in g to balanee bis m aebine on these groat g a n g lin g tilin g s ca lle d legs. T h is engineer's . l> ;m , T.ifis Cull.-ee Medical ........ I, Muslim, M ass;"' -rtts. n il is. H u s . too. "a s im s .itis f.u to ix b ' unknow n, but it was used because it icta.m x the enndition u n til bntbev inform ation n n |* slanding ol w hat be grateful if it coni _ -1 b' " ^ ^an im u.s " . w ()u ll, th a t'th e diagnosis SnfiSE&aan l & il = -5S ~P -C 1 ir 51 ^-5 s >ui^ .5 ,, .= - - ,, = = ? = = ?- i = 5il-sJiifiig-t 1 L 33 3i 2 2~ == -Mil M-ilJ = .2 ,, : I r.= 2 '' M _- = "'So1 1 = .22 - to = " I .1 13 3- 1 ? ss C =: tc = r- C ~ 3S| ilIl' <^1 j nI g 111 Ef t - = 1 15 -- I 1 II ^ S 3 | j 1I I 5 -1 3 J I ! I " E5 I V *t 2= ~ = x=2 S 5* U3t^ ^ * t - 3^ " rt - `s I -Ml 7. - U: Z -- rr" - v ^-- c -?- --- '2" 3 I2 t'- % =. _= = .2 = 1I 5 3 E ^ _r r; ~i* = o^ - n- "* ^>* ~zr, --x J~z '" 1" 3 " -^2 33 . I = XA II - ~aZ, B =* %z M . = Oi .2== *' o1 E "` r --Z i J= _ .. - = I = c" E -n2 " = .2 s i ~^ .- E= E MM ^~_ ----? -z ~c" -5 r-- 5 3 32 - ~H M j =- ~ ;r, _ 5---- ~ c =? 3- 5 z ~- 5^. - E g| ? ' - 0tf. 3 = 3' = |5i " f z~ ~r == rf = =| > 2- - c S X ?- r - .= = g 1I* s1111 1 Si I .. I 3 '5 X 5^ | 1 in_= 2 'E I-1-- *21 -- I :c .2 1 I I 1 Io- o .- w = = . % c- n 2 >. ^ ! * ;= 2 ; r .2 :i - r* ^ > = *> .3 " 2>--. ::.' E" - = E =t Ss = 2 -2 = ~3 co ^ 15 i | IM E = > -5 3 11 t 1C-t E-- "1 -- g . - >. =r to I 3- lil st 2 "B ? %" 5 2^ -2 5 =3 i" t> _ .2 -s ~ a .2 w ith h a lf as m u ch in v o lv e m e n t, as seen in his roent<m nogram , w h o c la im s he is disabled and m ust change his jo b . T h u s fa r, w ith o u r X -rays, b lo o d studies, chest m easurem ent, and v ita l ca p a city estim ations, w e are unable to a ccu ra te ly m easure the a m o u n t of d is a b ility o r loss o f w o rk in g c a p a c ity from a lack o f in fo rm a tio n on the p a rt o f men w ho w ere w ell-m eani and sincere in th e ir testim ony. T h a t has gotten us in to d iffic u lty , l he character o f people w ho are getting in to the p ictu re in com peu tio n decisions is o f h ig h c a lib e r-- its im p ro v in g ra p id ly and some nTTlMIMMYinim-ri 3w> I 'o C1L I ~5 .if 1 -P - 3 | if | SP 2 - -T ~ = 5 = I ,j J4I1 rj ! t 11 11 s r :1 5 -- ^ 'c c -s 5 ^ " .21 ~ It ,5 .S= t *Sx- ^~-i .~_*=r; = = = >*, 9y?= ^~^" -cs%* g _= C = S > .= -= Hr - ~ :i =j Ms 2 ~ .= l E -= s Mi;iil!2. .= J = = S. S' - > Mil<CNO if) =c 2 = i> -- r . _ .2 = t = = .2 C if ;= = x r: =2 X -= = *w _ -r = - ~ X - C * I cc *S i S=i t ~LS * s= OJ i >, y, -- j: o = J= t- ~ 1 < t* 5 J 1m ^ 5I 225 X n iJ | I 1 x% '5 r rr 2 .2 * x c M 'i ^ -C --2 ^ - --X - ~ S3P * i =- C j:1 - c- ^ 2 =x < ~ k=: X "2 =" % 4 - d 11 J M s -1 = | 3 .21 _, - 5 1 ~. 2 =1I c- * I *1 = =- Sc;c *_ n2 -oHI g 5 ^ C- c --c< -C=m' -Ct til1 i : I =-i i lili Hi2 ^ i ^I - ^U' 2M * ct -I I b ! =M * =" 4 Will Hi iiW'A= 4 > *c | II l .2 > =1; "Wc; )Ss> 2to ** t> If Jifiii , I r r- Z'*1 " " 9 - ill H 1 ? iH ^| " *2 -S * , 'H' H -r' 1 -5 | ? 141 5s irj 1 =4 .1 I I = SI *mf* tf. M * ~ 2 t 9 S = Sf> = |J T 1c 1 1 15 i i MU = Ko 2 2 .= = I ;i '3 s: 5 2 5~ S '2 . i p = : = s * G 2r. 2 c C I <5 if M 41 0 5 = I! 2 *2 " ~` > ~Z . > 2 ' . "22 s 2 2- -- 2 = 2 = 2 5 g ' 1 i rlI = 50 " I cj * 5 I * 1 = i >- ~ t; rf 11 ~. =* ^ c 22 ! i =. 2 -" 2 2 O & 2^ ^ .= r 2 x 2L i 1 2 I 5 B l %f j 1 I *2 1 5 s 2=22 === 2 | Li 2-- c .5 r , v, 2 r 2 i. to = ^ Hr s 22 Ic -- l! ;; c~ = c Sc ^2 2-2 c 1 fJ '= Z iS z 'c g c: 1 s 2 r 1 t- 2 1 !? si I ? n i r = - - = - = - 3 111 X X c -, " Ji 1 5= = " = '2 - 15=11 = 2 x i 1 E .2 v = I' 2 B 5 -2 " ;J 15 2 S-c" s= ! s =~: *=. --o ;.-; ~2x= "-- s. ^.-~ = = = =- = - II t ~ - .= -5 yx ~ 1 * 2 S 5'p1ba 1 i-I t .5' E= = S1 l|1o = ^ cs ^ -- -= ? 1 J- " 1: ~-- 2 -s -- -- --- iiLf^ ii f -f 11i a IsfiSlErn4 sI ti r ? i, in = 5: = -- 5T- ~ r; -- O r, ^s 7_X ^= f. =* = j] > " 2 .1 2>^ 2 - | 1 ^ -'c| Z 2 = = J % > .23~- 0'o s 4 I J< s - " 5 = =. = h im i`11 ^ Z 8-SlJi g -S- i ! | j f | i >= j, 1 ? c2l '5r 1C ~i ,, X &> 52c 1 f _ ""=3 - S -" 1- ^So S 44 t 1 , ..s- ,. - _= y * -- !z mif |c to o S' 5'-5i"2,"5;22 > CO = = .2 |= r 3 = = ? f-i i i - \ u- :Mi: r- .2 4 =s ~- 2 = i i? isw - :. ,,=r 1 S f - | ; = ~ = 1 | ~ s l t Z 2 J -:,. > r s-M -= E is ~ = 2 CO 3 -p S 5 S J U E 1 -:i H - u M" 3=' = 4 I ^ P7.2^---zfJJ -=._iZ " t C =r: = g-s- =='? ^- f .S . T >\ "5 ' - -zT i'?'z-r _iS2: ,_-S____ '? '= | J2 5 =^ Xs 1 = I ~ S _ilZ 7s si - 14 4^ \ II = ^ J; -5 --= S' S' x Hi- ^ -- I 2 - ~ y -- = CO " _ _c 7 = A - ? 5 -g. -5 2 .2 .2 I = 1 -g = I -f ? ~ = 5 < I? I --c-c-o n -- xc v. 222 : " -- g ' i "5 "g S2 2 liUHr y 5 j* 8 2 = .= D II " = -2 '-= .9 ~.T jC K 9 ! 3> I ?1 =? --^ 0= r s _ - .I o O' o 2 i 1 if 0 f2 111 1 % I I % X* .i - -= ^ 5 = 1 I ^i n 1=1 : i fit g 5 I K ^ 2 -1 r- CU rt P }]{ 1? 1= I& ill MS :j 111 > 5 ! _ r = 1 fl"5 ^ I 5I 111 m O .a """* n - -j - S 1 2 S' = 22 X 2 | i c rs ? I r " S E 5? 7. . -- V1. C /f 1 believe th a t th e ir a d m in is tra tio n w o u ld h r m ore successful. T h e re is one fu rth e r s u b je c t th a t 1 w o u ld lik e to to u ch upon. O n e o f the p rin c ip a l purposes s o u g h t to be a c c o m p lis h e d b v tin* W o rk m e n 's (N>mpensation Law s has been to reduce tin* to ta l injuries sustained b y the em plovres in the course o f em ploym ent. In r 'V a lly eserv one o f the E r- r c 1 HI g 3| E = tv. cS r "E r" -- ~ ` t/,, ~ ^ = 1 S = .2 - .9 = *r J: 1." z: = ? = .2 =/ = 2 = = 2 T C- 2 _c 2 -= ~ I == = 2 III ^= y. r mi 2 - = 25 ' - " E - = .-=' 3 e- 2 s E 11 = " c = 3/ y " 3 3 t= 11i r: I Z B i = I E 3 I. O a Participants in the Sixth Saranac Symposi none 22 2? I . r ^ ,; < S' = =" =? .. a- 1 5tC -= "k I 1 2'Si |f j 7 '=?: = = x- = m t- ^ i = Hi ____= .1 E C x" ~ ii 7 a iH t i) ii ss -u:=1 111i i s-tS = -= = 17 ? =1 = ^ ^ 'X --Jj J| 2 nii ^ c=In15r '<* --' . *41 a.l i- 21 I - E "><S <= -- i : r - =, 2 i > i -i i y inti 1 = j . _= y w-5 5X ='^-2r 15 Hi:;. --:l I I U P- t > 1= 1'<4 "2% c=x-' -nx ~Z ~ 2 >- ; 7 -/ ? .= = ~1*2 " \ii 5 y = = `S = * - c 4i X 7 = a-a =- - = | '/ x> U~ aI = -j = / ? 3 U -j a .- = i -5 'a f; ? ^ *M**l I'l 0 1 ^ I p -- '= y: -- r? - i1 I r'-s y rz Hi jf; 1 * iiiiJ ill ill= 1/5-5 7 i 1-^ = 3 = 9-'=-= ^ ~ Jr Ml ? a rl.ll ~"-; -- *c < ?^s y ?~ 5 2b ? k x =r= - 1 -i E a i = ^. ^ - - 2. '- bb, ~r -1 **1-^1 > = - r ^ Iv 7 2 _ ~ ~^ *= T? ,r .r -< J_ ill <. 1 =i =~-- =- c: ^ ^ * r -~ \!\IM fc m .E a a. 0 acrm,.vKuunmmtm -O 5 I ,c 1 . f-- . illflf y. y y y c/5 co 5 4 5 :r |- 3 s5 s >-' -5 2E 5 u*j -c -<.< ^ -c ^ ~ 2 = ^-- -~ ~ ^r E 3 "E- c c 0 >. a <0 1 _D CD c o mi CN M ->r . JU I JIM 1 I | <,, r J I M X U-l dllltlii IlliK III ei - > ? in jZ V. , c. " = ss fr. 2: -= ^ "5 E= != * s* r ts M 2 2 IS |2 .1 Is= c. -e -- ,= ~ V= : if 2 -- .~ =s ^ b- I r~~ ?= s. ff >, ,: wO i? . .1 5 i - =I!f ;i 2 "H. r P3 ~= M ~s = - i *- MliIf > =- (J 3 -= f 'o " ~3 5 =.= 5 ^EH i^l isir i-' ? = x rr i > ? IJ !- c s <n5 3 <"-??! G _ " s- --' t: to 1 _D 00 co -S ^5 "O < KS& r<~ r m o o S O S Is I IH 1 i O ! ion co nc 1 = ? ll 1." II S J'i 2 -1 = -1: lih ? E i2 11 |l :jl 11 HI ll '; 2~ ^- M =m ii O - c ----2 ^ pj J?2 -I | Is ^ I| E < ! 2 I iO > A "5 C! CX if Hill- 11 P ;o I l~2 .I2 |1=J >> a 5 >" 'i ; "l IBlfsil = = *2 ^ <- ~u -Iti nil.n nc E = e = 2 - '7 SS ;= 2 i ci ^S i! 23 2o p 2 ,2 a "* < co cc ci -j:  Oil, x 5 c~ c/: c v' .5 i .5 i rs 111 iJiillil 1 ^ If ISS 2 ^ "~ 'j'. .z , _' ^= &<r. = ._ -=| i: x :,s . ii= % l ~ --, Z VC I* 1 * c"' 11 ii M 2 = , 2 S ! i 2 I -A :|oi f | iS II I i S " J I- -= " --' : = i ^.-1 = - = := < r =* N. ' = i 'D : 5i ^^ =3> * *;l h l% \jus : Iz =.= = - -x__ ~ t ~ r v; M.i,, = *1 -_ r. = ~ v=o -0 -1 tr. 1 i -- ro = < = ;* hi -J = ^ . 5,' =j S 2x ^ 1J = 5i -|l| 2 ~. J s I =:! s . ~ >= S -- ; 5 C-V (;'] ii i ^ i I - x -r -- -- tJ, -- II J 2 ^ ?g ? .. I I o -j 2 "= J 2 ?. 1 2a- 2: .=; 1 f i==.. > J _ ~ ? -- c--- - = 111 sr ir*.= -I-; 1 iu f - r - --1 = = . ^w `B ?i 1G =H y -- < >. ~i z. -- ~ n EC 211 I IE . __ s --5~ .* I cc 2_i ?J !f =^ I 2 ,|! '-iZ- ?!:. r_ . i J i S . u ?, 5, "1 u =2 "5 '- -=u I| lo w -A | l1 i= V*. *~1 ! 4= C-l 'TS 1 Ji 211|J= I =!j r- | ". c o 5 2 =4 I -s r" ^ fg - a = P= =P P . 5 l2 J 1 i-S I =- --* r -j~. _"<c= .& 41 n 5 u _r 'P 12 1 "-- S -r r N 1= - -3 '2 *= 5 i ~ rC (J = J^ X -r; 75 a 5.5 r~ =-n m *4 i% ~ ~ ,, = P ~ - c, r = 4! 5 -; .= P E.2 : ~ c = -- 2 *5 . -1 I CO - 12 ! 1,-s la |S|i s 3 I t IipiiJ <?i rt I* I Crt -S ^ 2 C5 =i s S *? s a i ~ = b ' = fJ-M J s & Hi Imm = = - - r -> I' g S .~ Hi = -i sfS ~ rr- --> a a as 4 >- C3 ^ c == !-11 X i . = <M ~ = d-^ s~ s. .,,-S. X";i='^" n S^-S I= -s ` 5 Mi :?a>'S?ss 5 M F""5 5 i: - ~ m = - ^ = ~ i | . Mi I ? ^ -I-- . ' --r-- -- .s ~ -- *X, s-r -- -: = -- lf< _. E 5 * ?' M H M = -ills s5, 5= i~ - ~- I a . 5 5H t- X ~ X 1 I~ = = . - ^ i^ - i ^ H si ^ ~ 1 - ^ = y. 01 5 ~ -r -- *I I% s _j j hs =:? ; 5 ;c' lij n N iriiini i: J l I u; .E U t3 < y := W ~ -- -C -- D -- y. 'j.:-= i i 2 22 - ci S 1c X S ?1 s i- i $ at < l 5 1 LO c^' 3~ rz >.= s Li = s Is fill lii; - "=^, ~ |I IS Si ' iii -c- ^ <*.. c55 JlBcfl oi a 0Marrl"r^lT>h>r<WK.-i riffiiV TiYiViii --rYu'ii--iimnini JUUOtafhMda 2^ * i= iO 4O'e2r 5 i C5 H ,i< . ~ J I, o 1 ::J oS =lin a82s sas2 - -T"~?vys*,v*5yT^ ^w.V'WS^ssK'i^ * '-' S-.ljaiErT-WWiSWf^v g co II  Vi7?-rt otwf>'ut-vw*wn TT rtv 8 as iiss^sxaamiiisamaaii i? 1 K. YS = = ~ = ^ *t n -a 6> E ^ I 2 " JJ|Ml fi !Pli* lllji.!4!5!Sf 11 lU ill Its I| 1-s IIHJ ? ^ \i f2 s n,2 % a it i lie 1N cc ii5 5 i: 2 5 Cl .1 Yu 1 .1 '2 PS il H' "sfaiji "`112 _ i'l C- ~ = :. <r~' s| 2 N = .j M Nil 1 N~^' 5 S S S cS 1I C C5 2 "D "O < in H ^ OJ vo lO 11C00O 2I ~I Si 'c 5 _a M3 ll I- II li fj z \J -- I g CN -- O 3 .11 3 07 c6 rr CC <o <z = jhjai 1y. ?l 'ryDi i1s9 fe S5 i 1 2 11 T|==" ry=- "5=== 'w&d=. <1 <j. <.|= * Os' = 7; ?s P 77 s; 5 =' |I -a C5 IS|2 -i z"c *" 2 . - i'l a. d= 2 P 1 a 1= li -= = s: -- -i5*SS C s~ < ^ ;G ~- 1 5i . -= '= = i2 = -X 1 .H <> <=- ?? _=^r , p? ^7:. c,,= r=% = 'H - - p? * - E. . = i.n ^ 'c < i- :c C7 CS 3 5 1 Cl Cl Cl cc ;c III! 5 ! g I I 5 SSftG1 i'S C3 I ?2 y,*-55 H 1^1 s? 11 P a I? n i-t 3 S J;` = ' ]i -- ^ 55 IIi= . Cj J^ ]'l11 T- *.z == "5 .= if 1: i! = s p-= =S 2 ='i .1 j? Hi li II *1 y. I J . 5 ^ P. ~ H <n * = 3; z -a |fsf| a SSg I Efe Ilf Hi M" kI 5 r^ls 4iS li. ci ci $ -i^rrr !. 8 .= S sittiit i ? i mi i ?i.1 g z 2Lts s 2 *3 SsrS = - I S ?"= - .  0 AFFIDAVIT CITY OF SARANAC LAKE, NEW YORK, TO WIT: BEFORE ME, a Notary Public in and for the State of New York, personally appeared 1 C? ^--') O f \J \ ___________, who stated under due oath of law as follows: the Trudeau Institute, Inc. Medical Library, Algonquin Avenue, Saranac Lake, New York 12983. The Trudeau Institute, Inc. Medical Library contains original volumes of the proceedings of the Sixth Saranac Symposium sponsored by the Saranac Laboratory of the Trudeau Institute, held at Saranac Lake, New York in 1947. The pages attached hereto are true and correct copies from Pneumoconiosis. Sixth Saranac Symposium, edited by Arthur J. Vorwald, M.D., copyright, 1950, by Paul B. Hoeber, Inc., which are required to be maintained in the Trudeau Institute, Inc. Medical Library. The pages attached include the Preface, the Contents, and pages 3 to 659. STATE OF COUNTY OP deleft -lifrvi'r duly sworn, deposes and says: AFFIDAVIT - PAGE 1 OF 2 AFF710/TF700/August 14, 1990 Affiant, being first That the foregoing statements are true. i r1 A - .9^0 SUBSCRIBED AND SWORN TO BEFORE ME on this the of August, 1990 day STfm.FY C. PRFFTON' Notary ru'.iic, St.'te of New York No. ;7-:>i5$ooo Cunti'iec! in Franl-.lin County Teri Hapirei //?//?/ AFFIDAVIT - PAGE 2 OF 2 AFF710/TF700/August 14, 1990