Document KzmDYzZGBR8NE385Y4yb4rD4r

Castleman File: American Petroleum Institute w/c = with cover letter or memo If DATE = 0, undated CD-ROM Document #:API 1> / DATE published article from trade journal published advertisements newspaper article published government report government inspection results unpublished or internal report unpublished presentation from conference letter memorandum industry warning labels industry sales literature industry recommended practices meeting minutes (with attachments) membership list BC notes DIVISION OF TECHNICAL SERVICES AMERICAN PETROLEUM INSTITUTE AGENDA MEDICAL ADVISORY COMMITTEE Monday, April 9; 1962 9:00 A. M. Buckingham Room (Third Floor) Pick-Congress Hotel Chicago, Illinois I. Opening Remarks II. Introduction of New Members and Guests III. Approval of November 13> 1961 Minutes IV. Subcommittee Reports (a) Operating Subcommittee - R. F. Schneider, M. D (b) Atmospheric Pollutants - C. L. Samuelson, M. D (c) C9 - C]_2 Aromatics - Kieffer Davis, M. D. (d) Certificates of Appreciation - R. E. Eckardt, M. D. (e) Dermatology- - J. W. Osborn, M. D. (f) Epidemiology (s) Industrial Hygiene - G. M. Saunders, M. D. - J. A. Spence (h) Medical Policies and Administrative Practices - V. C. Baird, M. D. (i) Physical Agents - G. H. Collings, M. D. (j) Specialty Petroleum Products - C. H. Baylor, M. D. 00 Toxicological Reviews - H. W. Gerarde, M. D. V. Report oi (a) (b) (e) (d) (e) (f) (g) (h) (i) (J) Liaison Members Air and Water Conservation Committee - C. L. Samuelson, M. D Interdivisional Committee on Asphalt - J. A. Spence Interdivisional Committee on Labeling - A. E. Dooley Oil Mist Liaison Committee - N. V. Hendricks Interdivisional Committee on Petroleum Food Additives - L. E. Curtis, M. D. Quarantine Service - G. M. Saunders, M. D. Advisory Committee to the Wax Research Project - R. E. Eckardt, M. D. National Poison Prevention Week - J. W. Osborn, M. D. Walsh-Healey Public Contracts Act - W. L. Avrett, Jr. U. S. Public Health Service Liaison Activities Air Pollution Dermatology Epidemiology Industrial Hygiene Physical Agents Toxicology - c. L. Samuelson, M. D - J. W. Osborn, M. D. - G. M. Saunders, M. D. - J. A. Spence - G. H. Collings, M. D. - H. W. Gerarde, M. D. API 07739 MEDICAL ADVISOR'.' COMMITTEE AGENDA (Ccr.-ir.ued) 2. VI. Relation of Medical Advisory Committee and General Committee of Division of Technical Services VII. Possible Reorganization of Medical Advisory Committee VIII. 1963 Budget IX. New Business X. Adjournment API 07740 AMZ?,, DIVI r MEDICAL ADVISCHY COMMITTEE 33HP MEETING 9:00 A. M. Monday, April 9> 19&2 Pick-Congress Hotel, Chicago, Illinois MEMBERS PRESENT: R. F. Schneider, M. D. , Chairman G. H. Collings, Jr., M. D. , Vice Chairman J. W. Hammond, Secretary T. E. Allen, M. D. V. ^r\ . Baird, M. D. C. H. Baylor, M. D. F. F. Boys, M. D. L. E. Curtis, M. D. (Represented by James Ryan, M. D.) Kieffer Davis, M. D. F. D. Gassaway, M. D. E. V. Henson, M. D. E. K. Linder, M. D. J. W. Osborn, M. D. M. R. Plancey, M. D. Stewart L. Rankin, M. D. G. M. Saunders, M. D. (Represented by J. B. Rather, Jr.) G. A. Sinclair, M. D. W. Wayne Stewart, M. D. R. A. Wise, M. D. TECHNICAL ADVISORS PRESENT: W. H. H. W. P. D. N. V. Barcus Gerarde, M. Halley Hendricks D P. K. Kuhne (Represented by A. C. Miller) J. A. Spence MEMBERS ABSENT: J. W. Crookshank, M. D. R. R. Dugan, M. D. R. E. Eckardt, M. D. H. R. Fourcher, M. D. R. Emmet Kelly, M. D. T. J. Kelly, M. D. Z. ?. Luongo, M. D. B. S. Miller, M. D. R. J. Potts, M. D. J. C. Ruddock, M. D. C. L. Samuelson, M. D. L. W. Sanders, M. D. Kendrick Smith, M. D. H. B. Snyder, M. D. !THERE PRESENT: A. C. Currier, M, D. Helmut Herrmann, M. D. . I. Hollis, M. D. E. C. Mattocks H. Van Rasite, M. D. 5. 3, Reeve, M. D. ?v-r 9v3r. , M. D. Standard Oil Company of California, Richmond, Calif. Esso A. G., Hamburg, Germany Fr.illips Petroleum Company, Phillips, Texas Staff, American Petroleum Institute, New York, N. Y. Royal Dutch Shell, The Hague, Netherlands Retired 2s = c ?5t?cDun Ltd. , London, England API 07741 ciir*'a j M. D. L TM3 v~ tn- V' Advis v ee _?_ r.glsr.d; H. Yer. Raalte . M. I., ?-yal Butch Shell, The Hague, - Hermann, M. D. , Zest A. 3., Hamburg, Germany; ar.d 3. B. Reeve, :cv* M*aicsl ndvJ sZT"y Ccnirr.ittss. ship: Chairman Schneider announced the following changes in committee member- New Cfficers: R. F. Schneider, M. D., Chairman G. H. Ceilings, Jr., M. D., Vice Chairman J. W. Hammond, Secretary New Medical Advisory Committee Members: H. B. Snyder, M. D., Humble Oil 8c Refining Company R. A. Wise, M. D. , Humble Oil 8c Refining Company Kendrick Smith, M. D., Tidewater Oil Company New Technical Advisors to Medical Advisory Committee: R. C. Burton, M. D. , American Oil Company J. P. Malia, M. D. , American Oil Company T. G. Nevins, M. D. , Humble Oil 8c Refining Company T. H. Mitchell, M. D. Humble Oil 8c Refining Company W. A. Rowe, M. D. , Humble Oil 8c Refining Company W. D. Seyfried, Humble Oil 8c Refining Company R. P. Sim, M. D., Humble Oil 8c Refining Company Wm. B. Townsend, M. D. , Humble Oil & Refining Company C. E. Fountain, Tidewater Oil Company III. APPROVAL OF MINUTES ACTION: It was regularly moved, seconded, and unanimously passed that the minutes of the 32nd meeting of the Medical Advisory Committee, held November 13, 19^1, be approved as distributed. IV. SUBCOMMITTEE REPORTS A. Operating Subcommittee R. F. Schneider, M. D., Chairman, reported that the considerations of the Operating Subcommittee will be brought up under the various agenda items so there is no need for separate action. The minutes of the Operating Subcommittee are attached as Appendix A. 3. Atmospheric Pollutants T. E. Allen, M. D., reported for C. L. Samuelson, M. D, , chairman of the subcommittee. The subcommittee report is attached as Appendix B. ACTION It was regularly moved, seconded, and unanimously passed that the report of the subcommittee and the reccmnendatior.s therein be approved. API 07742 I Aromatics Ihe report of Kieffer Davis, M. D. , Chairman of this subcommittee, was reaa. A copy of the report is attached as Appendix C. ACTION: It was regularly moved, seconded, and unanimously passed that the report be accepted. D. Certificates of Appreciation In the absence of R. E. Eckardt, M. D., Chairman, it was stated that there was nothing to report. E. Dermatology J. W. Osborn, M. D., presented the report of this group, a copy of which is attached as Appendix D. ACTION: It was regularly moved, seconded, and unanimously passed that the report be accepted. F. Epidemiology T. E. Allen, M. D., reported for G. M. Saunders, M. D., Chairman of the Subcommittee. Since the subcommittee had no meeting, there was nothing specific to report. G. Industrial Hygiene J. A. Spence, Chairman, gave the report of this subcommittee. A copy of his report is attached as Appendix E. ACTION: It was regularly moved, seconded, and unanimously passed that the report be accepted. H. Medical Policies and Administrative Practices G. A. Sinclair, M. D., reported for V. C. Baird, M. D., Chairman. The report of this group is attached as Appendix F. ACTION: It was regularly moved, seconded, and unanimously passed that the report be accepted. I. Physical Agents G. H. Collings, Jr., M. D., Chairman, reported for this subcommittee. A copy of his report is attached as Appendix G. ACTION: It was regularly moved, seconded, and unanimously passed that the report be accepted. J. Specialty Petroleum Products C. H. Baylor, M. D., presented the report of this group, a copy of which is attached as Appendix H. API 07743 A."__Ii vss regularly moved, seconded, and unanimously passed -- V*n -r\Q vi+ qo 2 C " p~ ~C . 1, Toxicological Reviews H. W- Gerarde, M, D., presented the report of this group, a copy of which is attached as Appendix I. ACTION: It was regularly moved, seconded, and unanimously passed that the report be accepted. L. Oil mist Inhalation Chairman Schneider stated that this group had been made a subcommittee of the Medical Advisory Committee, in place of a liaison committee. N. V. Hendricks gave his report, a copy of which is attached as Appendix J. ACTION: It was regularly moved, seconded, and unanimously passed that the report be accepted. V. REPORT OF LIAISON MEMBERS A. Air and Water Conservation Committee R. F. Schneider, M. D. , reported for C. L. Samuelson, M. D. who had been appointed as the liaison member to the Division of Refining's Air and Water Conservation Committee. To obtain a better understanding of what the refining people were doing in the field of air pollution and to acquaint them with the Medical Advisory Committee activities, a group informally known as the Liaison Group on Air met in New York on April 4, 1961. Representing the Medical Advisory Committee were R. F. Schneider, M. D.; C. L. Samuelson, M. D.; R. E. Eckardt, M. D.; G. H. Collings, Jr,, M. D.; and J. W. Hammond. Representing the Division of Refining were W. J, Sweeney, K. F. Beaton, Jerry McAfee, J. R. MacGregor. From the staff were L. C. Burroughs, W. T. Gunn, E. 0. Mattocks. The group spent considerable time in reviewing their various activities. The possibility of having a physician attend the CRC meeting, concerning air pollution, was discussed. In general, the meeting appeared to be exceedingly fruitful in informing each other of the various activities which were being conducted in the different divisions of the API. Dr. Schneider stated that he expects that these informal meetings will be repeated. Dr. Collings thought that the MAC should place more emphasis on the use of Public Health Service funds which are available to do research work on air pol lution. B. Interdivisional Committee on Asphalt Dr, J. A. Spence stated that this group expects to have an organizational meeting within a month or so. He expects to invite Dr. Wes Horton, of Kettering, Cincinnati, to review the background work which they have done on the study of asphalt and heavy oil streams. C. Interdivisional Committee or. Labeling In the absence of Mr- A. E. Dccley, Chairman, his report, which is given as Appendix H, was read. API 07744 ">>-g ~ -- -- 2S Fcod Additives r^-ar., M. D, , reported fcr 1. E. Curtis, M. D. , Chairman, that there ir.g of this committee ar.d there was nothing to report. Quarantine Service T. S. Allen, M, D., reported for G. M. Saunders, M. D., liaison member, whose report is attached as Appendix L. F. Advisory Committee to the Wax Research Project In the absence of R. E. Eckardt, M. D., the report for him was given. It is expected that the wax petition will be filed with the Food and Drug Administration within 60 to 90 days. G. National Poison Prevention Week J. W. Osborn, M. D., liaison, reported on this activity. His report is given as Appendix M. ACTION: It was regularly moved, seconded, and unanimously passed that the Medical Advisory Committee recommend to the General Committee of the Division of Technical Services that active participation in National Poison Prevention Week for 1963 t>e discussed with the API Oil Information Committee and the API Fire and Safety Committee so that a decision may be reached no later than November 1962 as to the petroleum industry's participation in the 1963 National Poison Prevention Week. It was suggested that the physicians consider recommending that their companies list, with the National Clearinghouse Poison Center, the name of one or more individuals who would be available to receive inquiries concerning their branded products. It was indicated that a couple of companies have done this and it has proved exceedingly effective. H. U. S. Public Health Service The following liaison people, with the Public Health Service, have been established with Dr. Anderson, Assistant Surgeon General: J. W. Osborn, M. D., Medical Advisory Committee; H. W. Gerarde, M. D., Toxicology; C. L. Samuelson, M. D., Air Pollution; J. A. Spence, Industrial Hygiene; G. M. Saunders, M. D., Epidemiology; J. W. Osborn, M. D. Dermatology; and G. H. Collings, Jr., M. D., Physical Agents. Chairman Schneider requested each of these liaison members to contact their corresponding member before the November meeting. The group expressed their appreciation to Mr. N. V. Hendricks for his great assistance in working out the liaison representation with the Public Health Service, VI. rsXACIc:; CF MEDICAL ADVISOPy COMMITTEE AND GENERAL CCMMITTEE, DIVISION OF API 07745 Chairman Schneider stated that the March 1962 News Letter of the Division cal Services set forth, in a very clear fashion, the reorganization of the free, the Department cf Technical Services. It also contained an organi st- 2 = well as -he membership :f the General Committee. There were no --her c ones s reersa possible reorganization of mi: - -v One of the items on ~h- General Committee agenda, which is set for :-oril 1-th, is the possible reorganization of the committees reporting to the General Committee. Since there are 1- committees reporting to the General remittee, it appears highly desirable to reduce this number. The possibility of creating four central committees, one on health, one on research, one on safety, and one on engineering and standardization, might be considered. If there were a central committee on health, all the health activities could be channeled through -his committee. On the General Committee are seven physicians, with two additional physicians being chairmen of committees now reporting to the General Committee. These physicians plan to discuss the possible reorganization further, prior to the General Committee meeting. VIII. 1963 BUDGET Approved 1962 Recommended 1963 Chicago Medical School (Hydrocarbons in Lungs) Critical Review of Atmospheric Pollution Literature Study of Noise Oil Mist Epidemiology Consulting Fees $42,000 5,000 2,500 2,000 $42,000 5,000 2,500 10,000 2,000 $51,500 $61,500 ACTION: It was regularly moved, seconded, and unanimously passed that the suggested budget of $61,500 be approved. IX NEXT MEETING The chairman of the General Committee has indicated it will be necessary for the General Committee of the Division of Technical Services to meet on Monday morning, November 12, 1962. With this schedule, it will be necessary for the Medical Advisory Committee to meet prior to this time. ACTION: It was regularly moved, seconded, and unanimously passed that the Medical Advisory Committee Subcommittees meet Friday, November 9, 1962, and Saturday morning, November 10, 1962, the Operating Subcommittee meet Saturday evening, November 10, 1962, and the Medical Advisory Com mittee meet Sunday morning, November 11, 1962. The desirability of the subcommittees meeting consecutively so that all cf the physicians could attend all of the meetings rather than have some of them run concurrently, as at present, was discussed at length. ACTION: " It was regularly moved, seconded, and unanimously passed that the subcommittees meet consecutively during the November 1962 meetings, starting at 9^30 A. M., Friday morning, November 9, l?c2 , and ending by noon or. Saturday', API 07746 --'.ere was no new business brought up by the group. A - .-.Jo JL rU'ti'Jii.j X The meeting adjourned at 10:40 A. M. J. W. Hammond, Secretary E. 0. Mattocks, Recorder Approved: R. F. Scheider, M. D., Chairman May IT, l$fc2 API 07747 | JC3 COMMITTEE USE OKU ! I APPENDIX A NOT FOR PUBLICATION AMERICAN PETROLEUM INSTITUTE MINUTES OF THE MEDICAL ADVISORY COMMITTEE'S OPERATING SUBCOMMITTEE 6:00 P. M. Saturday, April 7, 1962 Pick-Congress Hotel, Chicago, Illinois MEMBERS PRESENT: R. F. Schneider, M. D., Chairman G. H. Collings, Jr., M. D., Vice Chairman J. W. Hammond, Secretary V. C. Baird, M. D. (Represented hy G. A. Sinclair, M. D.) C. H. Baylor, M. D. L. E. Curtis, M. D. (PFA) (Represented hy James Ryan, M. D.) Kieffer Davis, M. D. R. E. Eckardt, M. D. (Wax) H. W. Gerarde, M. D. N. V. Hendricks (Oil Mist) E. 0. Mattocks (ex-officio) J. W. Oshom, M. D. C. L. Samuelson, M. D. G. M. Saunders, M. D. (Represented by T. E. Allen, M. D.) J. A. Spence (Asphalt) MEMBER ABSENT: A. E. Dooley (iCL) I. INTRODUCTORY REMARKS R. F. Schneider, M. D., Chairman, stated that G. A. Sinclair, M. D. was reporting for V. C. Baird, M. D.j T. E. Allen, M. D. for G. M. Saunders, M. D.j ar.d James Ryan, M. D. for L. E. Curtis, M. D. New officers of the Medical Advisory Committee were appointed the first of 1962 and are R. F. Schneider, M. D., Chairman; G. H. Collings, Jr., M. D., Vice Chairman; and J. W. Hammond, Secretary. New Subcommittee Chairmen are R. E. Eckardt, M. D., Certificates of Appreciation; J. W. Osborn, M. D., Dermatology; V. C. Baird, M. D., Medical Policies and Admini strative Practices. II. APPROVAL OF LAST MINUTES ACTION: It was regularly moved, seconded, and unanimously passed that the minutes of the November 11, 1961, meeting of the Operating Subcommittee be approved as distributed. III. REPORTS OF SUBCOMMITTEE CHAIRMEN A. Atmospheric Pollutants API 07748 C. L. Samuelson, M. D., Chairman, reported that his group recommends $i2,000 for 1963 to continue the investigation of the carcinogenic properties of certain polycyclic aromatic hydrocarbons, being conducted at the Chicago Medical School, 'under the direction of Philippe Shubik, M. D. The subcommittee also recommends that $5>000 be placed in the 1963 budget to continue the critical review of literature relating to the medical aspects 1 Co - Cj_2 Aromatics 2- - ) A-2 Kieffer Davis, M. D., Chairman, reported that his group has no request fcr money in 1963 since the project, under the direction of C. A. Nau, M. D., will 3e discontinued June 30; 1962. He recommended his subcommittee be maintained no review any new proposals. C. Certificates of Appreciation R. E. Eckardt, M. D., Chairman, stated he had no request for money nor any policy matter to bring up for discussion. D. Dermatology J. W. Osborn, M. D., Chairman, stated that there appeared to be some confusion as to who was the new chairman of the Division of Marketing's Hygiene Panel of the Lubrication Committee. Because of this uncertainty, the Subcommittee on Dermatology plans to continue their contact with Mr. Floyd Van Atta, industrial hygienist of the United Auto Workers of America, in Detroit, Michigan. E. Epidemiology T. E. Allen, M. D., representing G. M. Saunders, M. D., Chairman of this group, reported they had no requests for money nor policy matters to bring up for discussion. F. Industrial Hygiene J. A. Spence, Chairman, reported his group had no request for money in 1963 nor policy matters to bring up for discussion. G. Medical Policies and Administrative Practices G. A. Sinclair, M. D., reporting for V. C. Baird, M. D., Chairman, stated the group had no request for money nor any policy matters to bring up for discussion. H. Oil Mist Mr. N. V. Hendricks, Chairman, reported his group believes they need experience data of people working in an atmosphere of oil mist. Contact has been made, with the Allis Chalmers Corporation to see if their medical :ecords can be reviewed to determine the incidence of respiratory illness. To provide funds to make such a study, at a place to be determined as soon as possible, the subcom mittee recommends $10,000 be placed in the 1963 budget. The subcommittee hopes to have a firm recommendation at the November meeting. If possible, the subcommittee will try and obtain a grant from the Public Health Service to finance this study. Also, effort; will be made to have the results of the study published. Chairman Schneider stated that he believed the Oil Mist group should be a subcommittee of the Medical Advisory Committee and stated that unless there was objection, the group will be called the Subcommittee on Oil Mist Inhalation. I. Physical Agents API 07749 G. H. Cell gs, Jr. y M. D $2,500 be placed in e 1963 v Chairman, stated this group recommended continue the support of Dr. Glcrig and the I r i .,/^v> ... i i ~ C 3ir.ni~"$s cf thr Arr:9ri2sr. Ac-,i~rr.y oiT O'er*.*r.3.2_iTiC2.cgy sr.d Specialty Petroleum -Product; C- It 3aylor, M. D. Chairman, reported this group had no request for money for 1965 r.or any policy stter to bring up for discussion. K. Toxicological Reviews H. W. Gerarde, M. D. , Chairman, reported his group is recommending a policy change. If toxicological data are available from other sources on material pre viously reported by the API and if the Subcommittee on Toxicological Reviews finds the data sufficient for use by the petroleum industry, the API toxicological reviews will not be revised. The Subcommittee on Toxicological Reviews will spend its time preparing new toxicological reviews on petroleum products not previously included. If possible, the new ones will be prepared by the committee members but it is pos sible some money may be needed to get outside assistance in certain cases. IV. 1963 MEDICAL ADVISOR! COMMITTEE BUDGET ACTION: It was regularly moved, seconded, and unanimously passed that an amount of 42,000 be included in the budget to hire consultants, as the need arises. . 1963 Medical Advisory Committee Budget Approved 1962 Recommended Chicago Medical School Critical Review of Atmospheric Pollution Literature Study of Noise Oil Mist Epidemiology Consulting Fees $1+2,000 5,000 2,500 2,000 $51,500 $1+2,000 5,000 2,500 10,000 2,000 $61,500 ACTION; It was regularly moved, seconded, and unanimously passed that a budget of $61,500 be recommended for 1963* V. PZLAITONSHI? OF MEDICAL ADVISORY COMMITTEE AND GENERAL COMMITTEE, DIVISION OF TECHNICAL SERVICES Chairman Schneider reported that the recent News Letter from the Division of Technical Services reported on the reasons for the formation of the new Division of Technical Services to replace the former Department of Technical Services. He asked if there were any further questions. The News Letter appeared to have given a satisfactory explanation. VI. P0SSI5-E REORGANIZATION OF THE MEDICAL ADVISORY COMMITTEE Chairman Schneider explained that ar. item appears on the agenda of the General Committee which is to meet April IS on possible reorganization of the 1*+ committees reporting to the General Committee. It is hoped that this number can be reduced m number. The desirability of forming a Central Committee on Health was reviewed. .'0 conclusions were drawn. API 07750 k-k VII. liEXT MPT-TZ'j The Vice President of the Divisicr. cf Technical Services has set Monday mcrr.ir.g, November 12, in Chicago, as the tine of the fall meeting. This will near, that the Medical Advisory Committee will have to meet before Monday. The desirability of having the subcommittees meet on Thursday and Friday, November B and 9> and the Medical Advisory Committee on Saturday or Sunday, November 10 or 11, was discussed. The possibility of shortening the time for the subcommittee meetings was reviewed. ACTION: It was regularly moved, seconded, and unanimously passed that the Medical Advisory Committee subcommittees meet con secutively starting Friday morning, November 9, 1962, and terminate by noon on Saturday, November 10, the Operating Subcommittee meet Saturday evening, November 10, and the Medical Advisory Committee meet Sunday morning, November 11. VIII. NEW BUSINESS A. Study of Petroleum Products G. H. Collings, Jr., M. D. presented the need for a study of a great number of petroleum products to determine their potential toxicity. This was reviewed extensively by the Operating Subcommittee. While most members were in sympathy with the idea, the general opinion was that nothing could be done unless there was a specific problem that had to be solved. B. National Poison Prevention Week J. W. Osborn, M. D., who has been appointed liaison with the National Poison Prevention Week Committee, asked the group how extensively the API should get into this program. The possibility of requesting the Committee on Public Affairs of the API to develop material for use by the petroleum companies was discussed. Chairman Schneider suggested that this be brought to the attention of the Medical Advisory Committee for their action. DC. ADJOURNMENT The meeting adjourned at 10:35 P M. J. W. Hammond, Secretary E. 0. Mattocks, Recorder Approved: R. F. Schneider, M. D., Chairman API 0775 APPENDIX 3 REPORT OF THE SUBCOMMITTEE ON ATMOSPHERIC POLLUTAIiTS C. L. Samuelscn, M. D., Chairman The Subcommittee or. Atmospheric Pollutants met on Friday morning, April 6, 1962. Six of the nine members were present. There were 10 visitors. Subcommittee members gave various reports covering meetings with the Automotive Manufacturers Association, the Air Pollution Research Council meeting, the progress of the Lead-In-Air Committee Studies and a meeting with CRC Committee on Diesel Exhausts. Dr. Schneider; reported on a liaison meeting of certain members of the Medical Advisory Committee and the Air and Water Conservation Committee on the general subject of the effects of Air Pollution on Health. The meeting adjourned at 10:00 A. M. for a visit to the Shubik laboratories at the Chicago Medical School. While it is too soon to have any progress reports on the work which we are sponsoring, Dr. Shubik and associates showed us their facilities and some of the techniques being used in this study. The subcommittee reconvened at 1:00 P. M. with 15 visitors present. Members and visitors expressed their views as to the possible ways and means of increasing the effectiveness of the subcommittee's work. At the closed session, the following items were discussed. Certain recommendations are presented for Medical Advisory Committee approval. I. ORGANIZATIONAL CHANGES The subcommittee feels that it should keep other API groups better advised as to its activities. The subcommittee also feels that in return, it should be better advised by other groups of the API as to their interests and activities in the field of air pollution where matters of health and physiology are concerned. To accomplish this, the subcommitted recommends: A. That the liaison now in existence with the Air and Water Conservation Committee be continued but that such liaison be strengthened by: (1) Having the chairman of the Research Advisory Committee of the Air and Water Conservation Committee be one of the liaison members of our subcommittee. (2) Having the chairman of the Research Advisory Committee of the Air and Water Conservation Committee and/or other Air and Water Conservation Committee liaison members inform the subcommittee of such activities of the Air and Water Conservation Committee that have to do with matters of physiology, health, or medical aspects. 3. That liaison membership be established with other groups of the API whose activities might be of interest and benefit to the subcommittee, or with those groups of the API which might be benefitted by the activities of the s-utcommittee. C. That further organizational changes which might p best interests of the API be discussed with such liaison m. ~ c "ns s as scon as possible. API 07752 2 3-2 .at all groups of the API be advised that the members of the subcommittee to assist, if possible, in all matters having to do with health aspects RESEARCH As a statement of policy, the subcommittee feels that, for the present, if shall concern itself primarily with the aspects of bronchiogenic carcinoma, pulmonary fibrosis and pulmonary emphysema as these might arise from petroleum products and th=ir use. With this in mind, coupled with recent reports, the sub committee recommends: A. That the work now underway with Dr. Shubik be continued during the year 19^3 B. That the subcommittee, through liaison meetings, acquaint themselves with such work having physiological or medical potentials or implications, now being carried out by other groups in the API. Such knowledge might give rise to new and further research work either by new undertakings or by broadening or projecting studies now underway. Ill. LITERATURE REVIEW The subcommittee has reservations as to the value received from money spent for literature review. The subcommittee feels that more value might be obtained from timely and detailed critical reviews of certain current articles, reports, studies, etc., which might have a bearing on the industry or its products. The subcommittee therefore recommends: A. That the literature review be carried out by the members of the subcommittee. B. That any current article having to do with the industry or its products be critically reviewed by the subcommittee as to accuracy, conclusions, and industry implications with the possibility of drafting a rebuttal and possible publication of same. C. That the subcommittee have the right to submit such articles to outside individuals or laboratories for independent critical analysis. IV. BUDGET The subcommittee presents the following budget for Medical Advisory Committee approval: A. $42,000 for the continuation of the Shubik studies for the year 19&3* B. $5,000, or that portion of it that may be spent by the subcommittee, for outside critical reviews, analysis and comments on certain articles, papers, reports, studies, etc. C. L. Samuelson, M. D., Chairman API 07753 r i REPORT OF THE SUBCOMMITTEE ON C9 - C12 AROMATICS Kieffer Davis, M. D., Chairman APPENDIX ru The subcommittee met at 1:00 P. M., Saturday, April 7, 19^2, at the Pick-Congress Hotel, Chicago, Illinois. Seventeen members and visitors were present. Dr. Carl Nau, chief investigator, summarized the work in general which had been completed under this subcommittee sponsorship and gave conclusions resulting from data accumulated. All present agreed that the work had been well done and that the findings are of such importance that Dr. Nau should publish a report of it in a reputable and proper journal. The Subcommittee on C9 - C12 Aromatics will continue to exist until such time that its members review the manuscript on this subject prepared by Dr. Nau for publication. Meeting adjourned at 2:20 P. M. Kieffer Davis, M. D., Chairman From minutes, meeting of the Medical Advisory Committee - April 9, 1962, Pick-Congress Hotel, Chicago, Illinois t API 07754 I REPORT' OF THE SUBCOMMITTEE ON DERMATOLOGY J. W. Osborn, M. D., Chairman APPENDIX D The subcommittee met at the Pick-Congress Hotel, Chicago, Illinois, at 1:00 P. M., Friday, April 6, 1962. MEMBERS PRESENT: MEMBERS ABSENT: J. W. Osborn, M. D., Chairman C. H. Baylor, M. D. R. C. Burton, M. D. A. E. Dooley R. R. Dugan, M. D. F. D. Gassaway, M. D. B. S. Miller, M. D. H. B. Snyder, M. D. GUESTS PRESENT: A. E. Currier, M. D. H. Van Raalte, M. D. G. A. Sinclair, M. D. Peter Swan, M. D. James Ryan, M. D. F. H. Herrmann, M. D. R. E. Eckardt, M. D. R. F. Schneider, M. D. E. 0. Mattocks Standard Oil Company of California Royal Dutch Shell, The Hague Imperial Oil Ltd. Esso Petroleum Co., Ltd., London Standard Oil Company of California Esso A. G., Germany Esso Research & Engineering Company Standard Oil Company (New Jersey) American Petroleum Institute I. LIAISON WITH DR. FLOYD VAN ATTA. RE: CUTTING OIL DERMATITIS This subcommittee will continue the liaison with Dr. Floyd Van Atta, Industrial Hygiene Engineer, United Automobile Workers, AFL-CIO, in conjunction with the Hygiene Panel, Lubrication Committee, API Division of Marketing, as soon as it can be determined who has succeeded M. D. Gjerde as chairman of the Hygiene Panel. Should the Hygiene Panel no longer' be interested in joint liaison, the Subcommittee on Dermatology expects to keep in touch with Dr. Van Atta on the cutting oil dermatitis situation, which he first brought to our attention in I960. II. LIAISON WITH U. S. PUBLIC HEALTH SERVICE Through the subcommittee chairman's liaison in the area of dermatology with Dr. Donald Birmingham, Occupational Health Field Service, Public Health Service, Cincinnati, Ohio, we will attempt to obtain copies of "Report of Expert Panel of Dermatologists to Food and Drug Administration" for study by this subcommitree and possible distribution or recommendations to the Medical Advisory Committee. J. W. Osborn, M. D., Chairman API 07755 r> APFENDIX 3 R5PCRT OF IHS SUBCOMMITTEE CN INDUSTRIAL HYGIENE J. A. Spence, Ph.I., Cnairman The Subcommittee on Industrial Hygiene met on April 7, 1962, with five mem bers and three guests present. Liaison members to the American Standards Association reported on the activ ities of the Z-62, Z-3L and Z-h Committees. Attached is the report on the activities of this Committee on Acceptable Concentrations of Toxic Dusts and Gases. It is anticipated the Subcommittee's project report on "industrial Hygiene Aspects of Petroleum Refining Processes" will be available to the Medical Advisory Committee by November 1962. On the Walsh-Healey Act, the National Safety Council is seeking considera tion for revision of the safety regulations required under defense contracts. . The De partment of Labor has thus far given no indication of considering changes. The status of the Interdivisional Committee on Asphalt was reviewed. The Subcommittee members were asked to submit any pertinent information on environmental problems to the Asphalt Committee. In considering new business, several members expressed interest in labora tory fume hoods. Mr. N. V. Hendricks accepted the assignment to prepare a question- aire for distribution to the Subcommittee members. It is hoped this would give a pro file of the types of fume hoods used within the petroleum industry. This could be help ful to member companies seeking economic and effective protection for laboratory per sonnel . J. A. Spence, Ph.D., Chairman API 07756 >> American Standards Association Z34 Committee on Acceptable Concentrations of Toxic Dusts and Cases n ' Report to the API Medical Advisory Committee ..............April 1962 On February 20, 1962, the United States placed its first astronaut into orbit. This day is also noteworthy because it marked the first meeting of this Committee since December 6, 1956. The status of each American Standard was reviewed during the meeting and plans made to expedite completion of the ones in the hands of various groups. Approved American Standards Carbon Monoxide Hydrogen Sulfide Carbon Disulfide Benzene Manganese Chromic Acid and Chromates Mercury Xylene Lead Toluene Oxides of Nitrogen Methanol Formaldehyde Carbon Tetrachloride Methyl Chloride Trichloroethylene p-Dichlorobenzene (in press) Standards Submitted to ASA for Approval Methyl Bromide Ethylene Dichloride Standards Submitted to Sponsor (AIHA) Nitrogen Dioxide Formaldehyde Trichio ro e thylene Tetrachloroethylene Methylene Chloride Chlorine Methyl Chloroform Styrene Monomer Methyl Chloride Proposed Substances Assigned to Subcommittees Ethylene Oxide Propylene Oxide Propylene Glycol Methyl Ether Dipropylene Glycol Methyl Ether Cyclohexane Cyclohexanol Cyclohexanone Me thylcyclohexane . Me thylcyclohexdnol Methylcyclohexanone Nitroethane 2-Nitropropane Nitromethane Other Substances Discussed Cadmium Chromic Acid Silica Standard being revised Acetylene Tetra Bromide Diisocyanates Ozone API 07757 3-29-62 Allan E. Dooley. API Representative I 1) APPEEIX F ?e?:?.t cf tee subcchmettse on medical policies a:;d aikeni strative practices V. C. 3aird, M.D. , Chairman MEMBERS PRESENT: F. F. Boys, M.D. G. A. Sinclair, M.D. MEMBERS ABSENT: V. C. Baird, M.D. T. J. Kelly, M.D. J. P. Malia, M.D. G. M. Saunders, M.D. GUESTS: A. E. Currier, M.D. The subcommittee met on Friday, April 6th. . No project was assigned to the Subcommittee on Medical Policies and Ad ministrative Practices during the year. ' Discussion was confined to two subjects. The first subject was a suggestion that members of medical departments of companies who are members of the Medical Ad visory Committee distribute to each other copies of policies, bulletins, and reports that are suitable for professional distribution. The second subject was an inquiry as to what means or methods are available to control unduly prolonged sickness ab sence that appears unwarranted. As only two members of the subcommittee were in attendance, no recommenda tion or. either subject is being made to the Medical Advisory Committee at present. G. A. Sinclair, M.D. for V. C. Baird, M.D., Chairman API 07758 1) APPENDIX G REPORT OF SUBCOMMITTEE ON PHYSICAL AGENTS G. H. Callings, Jr., M. D., Chairman The Physical Agents Subcommittee met April 7, 19^2, with fcur members and ter. guests present. Reports were received from members assigned to cover recent developments ir. various areas of interest to the Subcommittee. Selected items of possible inter est to the MAC are as follows: 1. Considerable work is being done on development of instruments to quantitate worker's exposure to noise. Some of the devices are of miniature size and can be carried in the pocket of workers for hours at a time. 2. Development of a standard for noise levels in California industry was reported to be nearing final phases. Unlike other state standards now in existance the Calif ornia standard will probably be more specific than just an over all sound pressure level. 3. Dr. Glorig's office has given a tentative opinion that the recently announced Otocups (Rudmose Associates) are not expected to be a satisfactory substitute for sound treated hearing testing booths for audiometric testing. U. A short review of the recent developments in the effects of vibration on health has been prepared by Dr. Kieffer Davis and a limited number of copies are available on request. The Subcommittee recommends that the MAC continue to support Dr. Glorig's work by a contribution of $2,500 next year. During the year the Subcommittee recommended to the petroleum industry adoption and use of the International Standards Organization Criteria for Noise. Copies of this standard were distrubted to MAC members. G. H. Collings, Jr., M. D., Chairman API 07759 )) APPENDIX H PPPCRT CP THE SUBCOMMITTEE CU SPECIALTY PETROLEUM PRODUCTS C. H. Baylor, M. D. , Cr.5irr.ar. pv'OCfi v*"' Mr. Hammond , Drs. Csbo:rn. Stewart, Gerarde, Baylor (Chm) Excused: Dr. Hens or., Mr. Cole. Retired: Mr. G. Er.twistle Visitors -Fifteen Minutes of last meeting were read and approved. Reports of clinical research on hydrocarbon ingestion: A. Dr. McKay (U. of Vt.) reported no cases because the number has dropped almost to zero due to publicity given such cases and public education in his area. B. Dr. Mintz (Baylor U. - Houston) reported 37 cases of whom one died and 36 recovered. The data were incomplete as submitted but this matter will be followed up and reported in full to the subcommittee and the Medical Advisory Committee. Due to curtain technical problems and possible policy changes to be settled, the subcommittee plans to have a special meeting in New York City in May to which Drs. McKay and Mintz will be invited. In the meantime, the subcommittee members will have an opportunity 'to study the long-awaited report of the cooperative kerosine study under the direction of Dr. Edward Press (Evanston, 111.) which appeared in the April 1962 issue of the Pediatrics. The subcom mittee discussed the possible use of gas chromatography for hydrocarbon an alyses and measurements but decided, for the present, that the time is not opportune for pursuit of this technique in its program. The subcommittee anticipates that the number of cases of hydrocarbon ingestion will decrease markedly in the next few years for two reasons: (l) the educa tion of the public to keep these materials out of tne reach of children and (2) the increasing number of state and federal labeling laws covering hazard ous substances. The subcommittee would like to recommend to the MAC that it and the API participate by whatever methods they see fit in any sound program of public education directed toward the prevention of poisoning. Some discussion concerned other specialty petroleum products that might, sooner or later, engage the interest and activity of the subcommittee. We wish to record a minute of appreciation for the long and faithful service to the subcommittee of Mr. George Er.twistle who retired last year. The subcommittee requests r.o additional funds at the present time. C. H. Baylor, M. D. , Chairman API 07760 )) APPENDIX I REPORT CF XH5 SUBCCI-MITTES IN IOXICOLOGICAL REVIEWS H. W. Gerarde, M. D. , Chairman The subcommittee net at 3 Room cf the Pick-Congress Hotel. M. on Saturday April 7, in the Carter A number of visitors attended the meeting. Since the last meeting of the Medical Advisory Committee in November 1961, four Toxicological Reviews have been approved for publication by the sub committee. These are: Styrene, Cyclohexane, Sulfur Dioxide and Sulfuric Acid Mist. The next reviews to be circulated will be second drafts on Cumene and Kerosine and a first draft on Aromatic Petroleum Naphtha. This will complete the revision of the Toxicological Reviews on hydro carbons and hydrocarbon mixtures. Rather than revise old Toxicological Reviews on substances which have been adequately described in recent literature, the subcommittee will review, select and recommend a number of publications available on these materials which are suitable for use by the petroleum industry. This will make it possible for the subcommittee to devote more time to the preparation of reviews not available elsewhere on subjects of interest to the petroleum industry. An example of this is a review on gasoline which has been requested and for which there is a great need. I move adoption of this report. H. W. Gerarde, M. D., Chairman API 07761 1 --"nuTT g* -g.~ -, rv fr .nr" V . ks > > APPENDIX J :; ;il MIST IHHALAUCN Q -* 4'4-Q V. The first phase cf the subcommittee work has been completed with publication of "A Review cf Exposures .o Oil mist." This summarizes the best available information on this subject from the literature, official agencies and industry. The subcommittee continues to work closely with Dr. Stokinger of the Public Health Service in his animal studies of oil mist inhalation. Three experimental oils, representing past and current market cutting oils, have been prepared and submitted for test. One of these oils is scheduled for study in June and another in September. Availability of exposure chambers will determine the rate at which studies are started. Dr. Stokinger's studies to date have been done with a white oil obtained from the open market. This oil was selected to establish a base line for future work. Experimental animals include dogs, rats, rabbits and hamsters. These have been exposed at two levels, 5*0 mg/m^ and 100 mg/m3 with particle size controlled to 1.0 micron. Exposures were six hours a day, six days a week for over a year. This has now been completed and no pulmonary response has been observed and no pathology has been seen on the lung sections. Tumor susceptible animals are now under study and the first of these should be ready for sacrifice by this time. As a final phase of our work we are now trying to arrange for an epidemiological study of a worker group with long exposure to oil mist. Con tact has been made at a number of locations and there is some interest in a study by Allis Chalmers Corp. This is to be developed, and if it does not materialize, every effort will be made to find some other suitable location. We expect that such a study will take money. Due to the broad interest in this area we feel justified in requesting a Public Health Service grant for the work. This will be our approach when satisfactory arrangements have been worked out for a study. If a grant cannot be secured, or if for some reason we do nor wish to use these funds, then other money would be needed. There fore, we are requesting $10,000 to have available for this study. Approval of these funds is requested. N. V. Hendricks, Chairman ! 4 API 07762 r1 > APPENDIX K REPORT CF THE IXTERDIVISICNAL COMMITTEE ON LABELING Allan E. Dooley, Chairman Representatives of the API Interdivisional Committee on Labeling have met with officials of the Food and Drug Administration four times since the last meeting of the Medical Advisory Committee. The first meeting which was held in December 1961 was a joint meeting with representatives of the Manufac turing Chemists Association, Chemical Specialties Manufacturers Association, and the National Paint, Varnish and Lacquer Association also present. Each of the four associations made oral presentations amplifying their written com ments on the August 12, 1961 regulations. We believe that the presentations of the four associations made in December contributed to the extension until August 1, 1962 of the regulations concerning type sizes and labeling locations on containers. The other three meetings, the last of which was held- on April 5th, were concerned with clarification of the regulations regarding the labeling of petroleum distillates. The Committee representatives have submitted information on the aspiration hazard of petroleum distillates which was developed by Dr. Horace W. Gerarde of the Esso Research & Engineering Company and the Rutgers University Bureau of Biological Research. Dr. Gerarde's research which he kindly made available to the API Committee shows that the aspiration hazard of petro leum distillates is not a function of the amount of distillate present in a product. Rather, viscosity is the most important physical property. On the basis of Dr. Gerard's work, the API Labeling Committee has recommended to the FDA that only those petroleum distillates with viscosities of less than 45 SSU/1C00 F. be considered as hazardous materials following aspiration. The FDA is now considering this recommendation. A special subcommittee with Mr. W. H. Barcus as Chairman has been considering the necessity of testing petroleum distillates to determine if they are skin irritants under the standards of the federal labeling regulations. This subcommittee has not arrived at a final decision but it appears that very little, if any, skin irritant tests will have to be made to answer this ques tion. Completion of the revision of the API Bulletin 2511 on Precautionary Labeling has been delayed pending action of the FDA on our recommendation re garding petroleum distillates. Allan E. Dooley, Chairman API 07763 r )> REPORT OF LIAISON WITH QUARANTINE SERVICE TO MEDICAL ADVI3CKX COMMITTEE APPENDIX T Liaison with Epidemiology and Domestic Operations Branch, Division cf Foreign Quarantine cf the U. S. Public Health Service has continued. Since the last report to the Medical Advisory Committee on the 13th of November, 1961, there have been numerous communications from the Branch concerning, primarily, cholera, smallpox, yellow fever, influenza and the new International Certificates of Vaccination. Some of the information was felt to be of sufficient importance to the API members to pass on to the MAC. Some was not. Cholera In the previous report to the MAC, it was noted that there was a cholera-like disease in Manila. Subsequent to that time the disease was offi cially recognized as cholera, and on December 11, 1961, the U. S. Public Health Service recommended that all persons be vaccinated against cholera and that per sons entering the United States within five days from an infected area would be required to present a valid certificate of vaccination against cholera. A later report of the U. S. Public Health Service dated December 15th indicated that there were, unofficially, stated to be more than 2,000 cases and 300 deaths due to a cholera-like disease in the Philippines and that the disease appeared to be spreading. On December l4th, the U. S. Public Health Service issued a memorandum to "All Carriers - Air and Maritime" which reported the wide-spread occurrence of a cholera-like disease in the Riilippines and recommended certain precautions including vaccination. On the 8th of February, 1962, the U. S. Public Health Service informed us that during the period of January 21 through February 2, there had been an outbreak of para-cholera in North Borneo with 40 CBses and 15 deaths and stated that the Public Health Service would require a valid certificate of vaccination for arrivals from that area to the U. S. within 5 days of departure. On the 29th of March, 1962, we were informed that the epi demic in the Far East, which had not been well documented, had apparently subsided. At the present time only occasional cases of cholera-like disease are being re ported from that general area. No cases have been reported from Japan. Smallpox In December, 1961, we received information that the Congo was re quiring a valid smallpox vaccination certificate of anyone entering or leaving the city of Leopoldville. There has been an extensive outbreak of smallpox in Western Europe. The first case to be reported was from England where a man who had traveled from Karachi and arrived in London on December 25th had a confirmed diagnosis of small pox on December 28th. On January 4th, 1962, we received a report from the U. S. Public Health Service of a case of smallpox in Germany. At that time, Germany had declared Dusseldorf an infected area. There had been one imported and two secondary cases, the initial case arriving from Liberia on December 1st and be coming ill on December 15th. Since the initial cases were reported from England and Germany, there have beer., until the 29th cf Marsh, 1962, a total of 88 cases with 17 deaths re ported from England, Wales and Germany. England and Wales have reported 3 total cf 50 oases with l4 deaths, the most recent case occurring in the Cardiff area ir. Wales during the week cf March 19oh. There were five initial cases, all being API 07764 > 2- - t L-2 interned fro:.. Karachi in Pakistan. Germany has reported a total of 3^ cases with tr.ree deaths. There were five cases in Dusseldorf, 32 cases in Mcnchaukreis and cr.e case in Aachen, the most recent case being reported in Monchaukreis the week of March 26th. There were two initial cases in Germany, one being imported from Liberia and the other from Bombay, India. Yellow Fever There have been occasional rumors of cases of yellow fever occurring outside the known endemic area. However, none of these has been verified and as of the 29th of March, 1962, the U. S. Public Health Service has no new intelli gence to report concerning the presence of yellow fever outside of the known endemic areas which are outlined in the booklet, "Immunization Information for International Travel," U. S. Public Health Service Publication No. 38*+. Influenza On the 5th of March, 1962, the U. S. Public Health Service stated that influenza of the Asian strain was prevalent in Japan and parts of Eastern Europe and was reported from France. In addition, type B influenza was present in Eng land and in Poland and a further spread of both types was anticipated. On the 29th of March, 1962, the U. S. Public Health Service reported that the outbreak of influenza in Eastern Europe was subsiding, and only occasional cases had re cently been reported from Western Europe. International Certificates of Vaccination Early in February, 1962, the new booklet-type of International Certif icates of Vaccination was received and information about the new type of certif icates was sent to all members of the MAC on February 19, 1982. Prepared by George M. Saunders, M. D. 29 March 1962 GMS:ar API 07765 >) APPENDIX M PZPCP.T ok liaiscn with xauciai pc:ec:; preuenticn WEEK TO MEDICAL ADVISCHE COMMITTEE 1. National Poison Prevention Week - 19o2 The Congress of the United States passed a law in 1961 authorizing the president to proclaim a National Poison Prevention Week each year. On February 7, 1962, President Kennedy issued a proclamation "directing" the appropriate agencies of the Federal Government and "inviting" state and local governments and organizations interested in child safety to participate actively in programs intended to promote better protection against accidental poisoning. He proclaimed the week beginning March 18, 1962, as National Poison Prevention Week. It is expected that the third week in March will be re-designated annually as National Poison Prevention Week. The Public Health Service, Division of Accident Prevention, called an organizational meeting in Washington on November 21, 1961, to which the API was invited. Mr. Mattocks and Dr. Osborn attended this meeting at which time a National Steering Committee was organized. This committee agreed to focus on the prime tar get for 1962, "prevention of accidental poisoning among children under five." Mr. Henry L. Verhulst of the U. S. Public Health Service and Director of the National Clearing House for Poison Control Centers, was elected secretary of this Steer ing Committee for the 1962 Poison Prevention Week. This committee subsequently issued helpful information on ways to promote this national week. This material included sample posters, articles for the use of editors, suggested proclamations for mayors for city participation, a list of available material such as brochures, flyers, pamphlets, films, slide talks, addresses, an editor's fact sheet and radio and T.V. spot announcements. The effectiveness of the 1962 week will undoubtedly be analyzed in due rime by the National Steering Committee. The API did not participate directly, per se, because there was insufficient time to seek the necessary approvals. How ever, the availability of the materials mentioned above was circulated by Mr. Mattocks' office to members and technical advisors of the MAC with the idea of encouraging individual companies to participate in this Poison Prevention Week in their local and regional areas of interest throughout the United States, March 18-2^, 1962. 2. National Poison Prevention Week - 1963 and subsequent years. At this time the Medical Advisory Committee should decide whether or not it wishes to recommend direct participation by the API in 1963 and subsequent annual Poison Prevention Weeks. It would seem advisable to do so, especially from the public relations point of view as well as from the public health, pre ventive medicine and accident prevention point of view. The API, through the MAC, has actively supported reasonable legislation and regulations regarding the labeling of hazardous substances intended or suitable for household use. It would seem reasonable and logical that the API should continue to support educational efforts toward preventing accidental misuse of the many products which get into the home, a number of which are petroleum products. API 07766 r> - 2 M-2 I recommend that the Medical Advisory Committee recommend to the general committee of the Division of Technical Services that active partici pation ir. National Poison Prevention Week for 1963 be discussed with the API Oil Information Committee and the API Accident Prevention Committee so that a decision may be reached no later than November 1962 at the time of the annual API meeting. J. W. Osborn, M. D. API 07767