Document KN9OV5nor4r92nwk8e1rLgoN

Comparative Toxicity of Aroclor 1242, /draul 50E , and Pydraul 115E Aroclor Pydraul Pydraul 1242________ 50E__________115E Acute Toxicity Oral LDcQ-rats (ragAg) Dermal Minimal LD-rabblt (mgAg) Dermal Irritation-rabbit (max. 8.0) Eye Irrltatlon-rabblt (max. 110.0) Vapor Inhalation-rat (ambient conditions) 8650 >15,800 > 20,000 1260-2000 >7,940 >7,940 2.3 1.0 1.3 6.0 6.0 10.6 non-hazardous non-hazardous non- hazardoo Fish 96 hour LCgn Trout (ppm) Blueglll (ppm) values for 30E. 25.1 31.6 2.5* 3.2* 32 63 NeuroToxlclty - Chicken Demyellnatlon Teat Dosage Reactions and Mortality Histopathology of brain, spinal cord and sciatic nerve 10 g/kg hid. lOgAg for 3 days, b.l.d. repeated after for 3 da 21 days repeated after 21 days none none no lesions no lesions Subacute Toxicity - 90-day Rat feeding study dosage (ppm) 1,10 and 100 200,1000 200,1000 and 5000** and 5000 Qeneral Response None;pilot Possible Possible study indicated liver-weight liver weight gain increase at weight In depression and 5000;nonea crease at severe liver at 200 and 5000,none involvement at 1000. at 200 and 1000 ppm after 1000. 30 days. ** data for NgCP. Cholinesterase (plasma, BBC and brain) no effect no effect HONS C79580