Document KGJzZ2rMj8MEeVk844VoGLMq0

FILE N A M E: N e igh b o rh o o d Exp o su re s (N E) DATE: 1964 Nov 10 DOC#: NE012 D O C U M E N T D E SC R IP TIO N : M em o RE C o n fe re n ce on B io lo gical Effects of A sb e sto s Amblar Safety V. ` ee: . r . R. L . Lona - Ambler R r. J . L . Andar3era - Amblar t . Dr. K. -C. Shau - Amblar L, DV H orovita - a ? ^ j i j S u b je c t: -Conference on B io lo g ic a l E ffe c ts o f A sbestos New York Academy o f S cie n ce s S e c tio n o f B io lo g ic a l and M edical S c ie n c e s Hew York C it 7 - October 19-21, I9b4 -- /'-A re ao rt "was subm itted byy D rr-.Siseycn Hcvembcr 2,:-l?dia-wiiich-tharcwghlj^^SaiKSih t & xis& 'iX & ~ & B iic3 d isc u sse d fit t h i s co n feren ce. The p re se n t re p o rt w i l l co v er on. th ese p o in ts which req u ire fa rth e r em phasis. the d iscu ssio n ct our can tin g with the four re p re se n ta tiv e s fron Turner Brother: A sb e sto s Company tha ev e r.irl^ b d fo ra the conferen ce was m ostly on tha a c a o c p lish c a n ts o f the A sb e a to sis R esearch Council o f England. Although we did not d is c u s s the d ir e : help they could give us ^(C ertaip-teed Products Corporation.) they did point out that they ore cany y e ars ahead of the U. S . in awareness o f the m edical problems a sso c ia te w ith a s b e s to s by snqjhaaiisiatg :he fo llo w in g : < ; . 1 . As & r e s u lt o f an in v e s t ig a t io n o f tha e f f e c t s o f asbestos in tha lung by .tha F a c to ry D cpartnrsnc^ipH f^a. tha U nited Kingdom form ulated As bus tea I n d u s t r ia l R e gu la tio n s in 1933 fo r ^proper bust co n tro l in ind^dtry- 2nd a Pneumoconiosis Board vats e s ta b lis h e d in 931. The Board o f In su ra n ce ta* accepted a s b e s to s is as a cause o f lung cancer s in c p 1931. A praat Improvement wse seen a y a r e s u lt o f these re g u la r tio ns. 2 . Dr. Knox s a l U. S . indus: g e n e r a t e ioga not want to a c c e p t th a f a c t th a t a s b e s to s i s very hazardous arid they w il l ac ce p t cay d o c t o r 's view i f he in tim ated that i t Is not hazardous. 3 . A ll p re se n t agreed th at se v e ra l d o cto rs in tha 0 . 3 . have been re ce n tly cry in g to cake omasa fo r th ecselv ea by exposing asb aato a a s an a x tr o a s hazard a s evidecc by tha P re ss R elease covering the conference and subm itted to 1100 c i t i e s in Advance. v; - 4 j.. There* la> no ergaainn tinn . in th e U -S'. e q u iv a la o s> t^ T k ' b e ste d Bcae^jrclw ' C oun cil which was e s t a b lis h e d in 1957 in England. A ll the S n g lish eabeotoa companies a r e members end they have accom plished ouch re se a rc h in the m edical and environm ental aspects of asbestos. 5. They a r e convinced th a t th a method used fo r d u st campling and counting La the U. S . i s not adequate fo r a s b e s to s dust because i t does not Include long f i b e r s end very sm all d u st p a r t i c l e s which t h e ir re se a rc h hne convinced thee axe g re a t con trib u to rs to the problem, G. They ere a ls o convinced chat Che H a xia cn A llo w ab le Concentration, used in tha U. S . f o r a sb e sto s dust i s too h ig h end i t should be reduced. .Concerning the conference i t s e l f , thera appears to be cn accum ulation, o f <rvideaca of the a sso cia tio n of asbestos w ith cancer. The purpose of tha conference vat to exchange In fo rm a tic a on t h is s u b je c t. T h is m eeting, w hich vas the f i r s t o f i t s magnitude oa th is p a r t ic u la r su b je ct, included cany papers re la t in g asbestos exposure , S. D avis, J r . -2 - November 10, Xi o tso th a lio o ft c a n c e r. Ilic s o papers covered d iv c r a if i e d s u b je c ts cuch on th a g icrgy, ch e m istry and p h y s ic a l p ro p e rtie s o f a sb e sto s; the o e d ie c l aspects such ss b io lo g ic a l e f f e c t s , p a t h o lo g ic a l and e le c tr o n X -r a y s tu d ie s sa tro ll Z2 ncann ea p re v e n tio n end p r o t e c t io n o f those exposed. s* . . Scma o f the o b se rv a tio n s made which, i f proved c o n c lu siv e , would e ffe c t * out industry ere ec follow : * . 1. M alignant mesothelioma (cancer asso ciated w ith asb estos) has been found i a ca se s w ith no o c c u p a tio n a l exposure to a s b e s to s . These have in clu d e d p e o p le a: s a l a s l s visa liv e d in. a re a s su rro u n d in g a fa c to r y o r a m ine. People in the a re a ck bo e ffe c t e d by w aste duzna o u ts id e a p la n t, or n in e . 2 . The su sp ic io n that the asbentos fib e r is v ir t u a lly in d e s tru c tib le so that even m a l l co n ce n tra tio n s beva an e ffe c t i f lodged ia the body fo r lo n g p e rio d s (20 ye ars or c o r e ). ` - . 3. Asbestos fib e r s found in the base of the lungs o f urban d w ellers aa ranot as Cap.qtyva, South A f r ic a end M iam i, tF lo r id a j,'i t ^ no,. <?ccu gccicA el-c.ap o cp zc.'-to -sab c. ' Th a.'Jfd tslill'Ib ^ f' lie in s ` that isbeohoa"products used in every d ay-U fa"an y reiaaae as bestos fib e rs to the a ir . ' 4. The su sp ic io n that long asbestos fib e rs accumulate at the base o f tha lun; and em ail doses can thereby have a cum ulative e f fe c t . 5 . In c re a se d evid en ce th a t in s u la t io n w orkers and lig g e r a , w ish low exposure to asbestos d u st, are su b ject to cesothallo-. 6. Increased world production (2/3 in asbeacas-cenant products) has increased exposure to asb esto s. 7. In c re a se d age at death has made tho se exposed n cre su b je c t to c o m e r where p r e v io u s ly death was caucad by I . B. e t c . " 8. The p o s s ib il it y th a t p r io r exposure 20 c r core year before v i l l cause car. i a aoesa s u s c e p t ib le in d iv id u a ls in s p it e o f rem oval from exposure. 9. Thera i s a p o s s ib il it y that there i s a r e la t io n s h ip between a rs h in s and a sb e sto s d ust in h a la t io n whereby the ca rcin o g e n s in c ig a r e t t e smote a re trapped by fib e r s ia ths lung and thereby cause the can cer. 10. Persona w ith asbestos! w ill have g re a te r p o s s ib ilit y of death by ca n ce r. 11. The p o s s ib ilit y that cancer o f the g a s t r o -In te s t in a l tre a t .as v e il as-lung. can cer sa y be caused by exp o s-re to asb estos d u st. . ' : * I t was obvious th at the evidence presented at t h is conference v u not c c a c lu a i end fu r t h e r r e s e a r c h i s in d ic a t e d . F o r th in reu so n , tha In t e r n a t io n a l Union A gains Cancer a c t fo r two days a f t e r the co n feren ce fo r co o rd in ate d work to f in d answers ttbe many q u e stio n s introduce*! at the co n fe re n ce . The.pu.rpo. la ; to b rin g people, tng ath e r tcxkalp f a c i l i t a t e re se a rch fo r cancer study end se t up sm all, groups o f peopl in sp ecialized p ro je cts. The q uestions that need answers are as fo llo w s; 1. From the p a t h o lo g ic a l p o in t o f v ie v , what ia an asb esto s f ib e r and how car. i t be p o s it iv e ly id e n tifie d / 2. G ra v ita tio n a l e ffe c t of asbestos fib e r in lung. 3. E ffe ct o f duration o f fib e r ia lung, ' 4 . Study to see i f d iffe re n t type# o f asbestos re s u lt ia d iffe re n t types of cancer, i f at a ll. 5 . R e la tio n sh ip o f suoking and a i r p o llu t io n , e t c . to a sb e sto s d u st with reap. Co c a n c e r. ' , 6. P o ssib le other causes o f iseaothaliom t b esides asb estos, i . e . , other d u sts. 7. I s csb e o to sis a precondition to lung cancer? \ & .. 3 . D sv ia, J r . , - 3- Uo-cmber 10. . . 9 , -Saad fo r more and b e tte r eptdcuLolo^icjal (in clu d es *11 exposures) 'stud /er a vide ran^a. ' 10. I a Chara A d e te c ta b le senga t s b e s t u s is a t which progression cacr_-.v> removal o i dust ecaoaura? 11. I n t e r n a t io n a l a^reflissnc oa a in iic il c l i n i c a l , r a d io lo g ic a l end l u a j fuse c rite r ia tor diagnosis of aab aito ais. >. 12. I n t e r n a t io n a l agrsercaat on type o f duet naasurenen t to be node to c o atr a ll asbestos duet hazards. -t iihac can C a rta in -tc c d Products C orporation 'do to need th is.p ro b le m ? 1 . We skiat en fo rce our r e s p i r a t o r program and in clu d e a l l artuts v h sra duct exposure cay ha in te rm itte n t or even aeaain ^ly u e - lig ib la end duat. co n tro l ia not a v a i l a b l e . T h is would in clu d e niaintenancc and clean -u p c a n . '' ` 2 . P rovide duat co n tro l in a l l are as where expoaure to a sb e sto s f ib e r e x is t 3 . tfore frequent monitor in s of du3t areas to evaluate ,f fe c tiv e r ic s. o f t dust c o n tro l .jaaaauracl'-.-Tha- u G o ^ f crillcpore- fi'Itttr3"'cn d ^G r^irL l traduced to meet the nora a c c e p ta b le d u st cow titin* cathode f o r ae h e e to s. ; 4 . . l?sa a lover lim it (perhaps 2- 1/2 m illio n p a r t ic le s per cubic fo o t) c s t a allow able concentration for csbcetoa dust in o-r p lan ts. 3 . Cooperate w ith cba'U . S . P u blic H ealth S e rv ic e viten they approach ua .to z the epidem iological study ia our p lan ts. fi. Cooperate with oth er a sb e sto s in d u a trio a in any re se a rch p r o je c ts s im ila r to the A sbeatoaia Research Council ia England. _ -. * ' 7 . E n force the X -ray program no th at a l l p la n ts o b tain 14" x 17" 2 - r s y *p tc ta : a t pre-employment and a n n u a lly . Educate e=nployeea to knew th a t tha 2--rny progra-- ; a c o n tro l program u&ed aa e p re v e n ta tiv e measure to remove the enpioyea fr o a ex a cti exposure b e fo re he i s perm anently dasm^cd.