Document K694JbRaByGzdVzYq1BM6pEer

/ . n 1+ >^"JifcUW^ 2. of pneumoconiosis often come to autopsy sad provide a Toady source of ma terial for atudy. It s< In thle way that report! of the simultaneous occur* reoce of lung cancer and asbostosls began to accumulate after the report of a case by Lynch and Smlth^^ ^ 1935. Within the neat ten years, about 15 additional cases were rpported, and In 1954 Merewsther (761 rovlowed all deaths from aebestosls recorded In England since March, 1924, Lung can* Cer occurred In 16% of those cases. Gloyne, (411 ' whose work Is also frequently referred to as establishing a connection between aebestosls and cancer of the lung, reported In 1951 that cancer of the lung was presont In 14.1% of ashes* tosls cases examined by him. In 1941, Nordmann add Sorgo claimed to have produced lung cancer la mice which they exposed to asbestos dust. Since 1951, additional cases of cancer of tho lung coexisting with ICftV aebestosls have been roportod, and, according to Hueper about 100 such cases had been reported up to 1955. As a result, an association between the two diseases appoars to have been accoptod by many auUtors, and several | OQj writers were using the term "aebestosls cancer" of the lung. Worber In 1952, stated catogorlcally that in 7% to 17% of cases of aebestosls, after a latent period of about 1 1/2 to 20 yoars,'carcinoma becomes established In the lung, On the other hand, not all authors accepted this alleged association (80) without reservation. Saupo In 1939 roported that he had discovered no cases of lung cancor among 620 cases of aebestosls which ho Usd examined; (48) end la 1942, Hollob nod Angrlst oxprossod tho opinion that the number 0251