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CONFIDENTIAL
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Typedi 11/14
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Th* fsreaae Leberetcry** Proposal f feptezber 21, 150, to th ETlrlEj iscoolotloa eta^4 ib prt&lca mi
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*Tfc* epeelfio prehlaa If to aeosarlaija whether *r aat a rolatieaship exist# batvaoa the ishalaties f agboetoc teat cad priusry palaeecry fttsar.1
Thia report prepocod c pregrca for trylag to get sa caeear to title jrohlca. The p?Cra ooaelftod of tvo phasoei
1. Egldea illogical lsrartlaatlca.
2. Expcrissaatal imitljatlcu, lfi., duetlag ad ebdla| f calsolo*
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The report to the <^ebee lebertof Klalaf Aeaoelatloa ea Fajiwamiry Oaceer, dated Soptmbor 29, 1?50, which vu aeceptod 1b principle by tb Q, A. M. JL. st tbir recast ceetlsg, gottarally fll*vod, tut la brief, stroa Laboratery'f Proposal. A oaassittee of tbo Q. A. H. A* ocapoesd of feecre. Footer oed Sibarla pr*costed this report at thia recent Kootlxg.
FalUvl^ a dlecuecioa with Mr. A. X. fiibr, It vaa left that Mia era. Vsoderd and labourl*. mad Boaterf Tcrvald and Lea pa would ranrlev the Propeaal at doraaao to alesr y cay ^certloae that alfht bo open od errIra at o eea timelea aj to vhat la reecssaoied froa hero ea, Including vhe veuld do vhat, hov laig It veald tehe, cad how sseh It voald ml.
That vu the purpose of thla eatlss.
X. Shert-Xttje Fa^egrou - Syldoalolegleal fcroay
The ahart-raaga jarogrea was to oeasiet of c asrofally oad*etod lyliwlalegie&l surrey to. determine the l&sideaee of ocaear caeag people oxpoood to asbestos duct of osapared with the lnelds&ee et| those sot asyoood.
A, BAuaulfflt
1. Oar* Tcrvald** eeaussxt* varo ae follow*i
a. Ve abegirt leer* the inaideoco of eanoer aacag thooe expoaad to aaborto* duet and eatong those sot exposed byi
(1) 1 acrcful atedy of tha X-?cya af pac?la esplsyad in tba askoatoo ictujtjy, *
(2) A ctesiy of tba Z-reya ante ef tbs gomral pspsalatira* by tba Esbllo caii* af ihi Freriaainl S^trtoui if Eoalth (thoea eat ozp&cad),
(3) A ftudy of port-aortaa Aft on tb praM af waw at doath insofar m ruoh iafomatien say ba crallahla, Zi van pointed cat that la tba Prorinoa it la tha praatica not to lift otacar as a eeaca af Aacth rraa vboa it iat aa that iofcraotica ca tb.li y not ba af nuah balp to us.
Br, Leaaa aess&atedi
a. Tfca caa inpertant point la tkat va got ea gyrort oulAcftlfrlftgiat. l.o.f ana who aan tska tha job crar, do It acSTaatly and adequately, rad ae* up vith tba aorroat caawor.
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b. Dr, leas* agreea it la laportent that a Canollaa ba abacas to hflftrtla tba job. In camm a Ctaedian asset bo found vha aaa do tha job adequately, aanaono ftrtra tha V. 8. oca than ba trad.
Mr. Sahourla auggattadi
a. That prior oneultatloa with appropriate Canadian aathcrltlaa and a raquast for thalr auggationa on aortaln pbaaaa of tha pregrraa vould gat thalr taoit basking ad that thla wold loaterlally strangthan tha baaa of tha parogrtt, Aooardlagly, Mr. Sabourin agreed to rarlav tha natter vith Etr. Tidal and alao to arranga ao that Hr. Yarvald will ba ablo to ba in touch aaally vith tha Daaa of tba MaOiLI fedlaal Sehoel (ar Sr, Tervald vlll da aa, aa raj ba daeldad between tba two af thsa). By thla arr Mgaaant, Dr. Tidal and tha MoQlll Daaa veuld kaov of tha pregm and thalr balp aad fuggaaticea veuld ba aeugbt in hoofing an abla apidealolaglat to carry out tha first part of tha pragma. Earing df aided aa tba lndirldaal* vha night ba aeaaldared fee tha job. It would then ba up ta Sorenaa to nika final arranjaoonta .
b. In addition to tha ay idealologlatt a aiatlrtialaa la naadhA, Miff Rom has baaa auggaitad aa an aaaditaat. Thla oas bo veefcod out by Dr, Tervald aad Mr. Babcruln in Una vith tha situation and tha vlahai af tba Q. A. X. A,
It vaa tba understanding alaa that X-ray aoawltanta veuld ba aaadad and it vaa tba oobmeufus that Poster a Snlth and Cartlar eocld da pralialnjry laraaning of X-cy, vhlah vauld laara Sarane# only
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the Job of studying theca which vculd be punt to Sarcoma. It
vac pointed out that the two etsspmgr <dootorc should sot be
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objoetlrity of the otsdy ted till gs^canc cca dotcmiis* ,r
I, Cesslnslcasi
X. Doctors Riith and Cartier vill screen X-r*yi, than ScricsM vlll Bfi&e tb final study on the X-rays that hare been screened oat fer thee,
2. In pidsniolegirt vlll bo cboaan, aa out1insd sbanre. Saranac vill make tb approach vith a view tcverd Baking final arrangeasst* vith tho nan who ha boon tentatively chosen.
J. Tba cpi&alolcsieal ropert aa first nedo vill go to Saranac. Dr, Lease vill rslnete the report in this font and suggest beet use of the report, revisleac that night bo node, and other cmah natters. There should be discussion between Saronoc, the nndoxwriting organisations, end others interested as to the tinellaosa and propriety of the use ef the notarial developed by this report. It Is Important that the report be gv allable only to the waiterwriting ooapanies end not node gemrally available until it hae been reviewed vith and by the pgapenlos.
4. Saranao Laboratory is responsible for the program.
a; iS cranio it to make the final err*ngasnt with the epIdealalegirt and others to nske the study, and la alao responsible to heed up and supervise the study.
b. The jsrogres should be started as eoon as it is possible to do ao.
o. It vas estimated that tba Job oeuld bo daeao in sir months if a qualified epidemiologist oan be obtained vho oaa daveto a raaaonahle length of tine to tha study. It lo desirable that tha job ba done in six mouths and tborafora the parson hired fox the job should bo lnpreseod vith tbs fmt that tha study should be pushed and ecsaelusions reached prenpOy.
d. While tha original prugrer. stated a posalbla oast af $4,000, it vas stated in the discussion that the ooet night run
A between $4,000 and $4,000, it being thought, however, that $5,000 would be adequate.
II. Leag-R*nga Prograas - 4 re so sr oh pro^raas of perhaps Wo years' deration in Wo partsi
(1) Tht trsnaplent log of asbestos and embryonic tissue inte animals (originally suggested to be under tha guidanoa of Dr. Laasa ead his gro?).
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(2) Stilising the facilities at the Trclsca Laboratory, os La the past, and subjecting enixAls to high acbostos dust ec^diUtaj,
A* Diecuesleni
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1, Rr. Leas* sold that he la not prepared to gsjttj sat a fcraal
projeet as eentletsed la (1) above} tha^^^^l3^l%i
aloof
with Dr. Sutherland associated with hla, la doing 'pens of this
with fifthly ground asbestos, aa veil u with sons other a*ter1_k1o.
2, Dr, Vcrvald gcre tb fcllcrwing infcmation about part (2) of the pregra, which, of osatroo, is given in acre detail 1b the foresee laboratoryra Proposal of &pts=obor 21, 19501
a. Set up a program oeaslsting of 300 enirtala to be subjected te asbestos cad 300 ecatrel solaala.
b, The psrogrcst ia likely to lest for two years.
e. It would probably take two Booths to get enough of the right kind of anInala end get under way.
d. Quoting Dr, Vorvaldi *Ve hope to show or prove that saeoor inside nee is not Increased moag these animals even if dusted." It was mentioned that auoh re suite are oa the basis of aniaol experleentatien, the results are, strictly speaking, true only of anisala, and it should he realised that the ae*e results Bight or might not hold true In the case of humans.
3, It was agreed that, while the leng-range progrsn is going an, Saranae would provide each four Boatha a progress report an the work.
There was scoe question as' to bow ocaplete a progress report should he and it was agreed tLet e progress report sight well be of no sore then two typewritten pages to show in ooaeiee font
a. ,Tba work that has been ecapleted up to that time.
b. Sow the work is progressing at the Bcesnt.
0. What the future work looks like, i.e, as to when ocxyletiea Bay be expected and whether or not the program is ahead of schedule ar behind sahedule, and by bow Buck.
d. Vbet general conclusions there are, if any, at the Buissi, without giving detailed date cm the vat,
4 . The present idea is that the two-year progress eon be undertake a at
an estimated oost, as shown in Saranac's Proposal of September 21,
1950, of $16,000 for the first year, and $10,000 for the ssseod ,
year.
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ehcvo, to shew tha vzy la'vHleh tie* jregrea vcald' progrop j,: cad
tfca vac that tin prejra should ho uc&jxtfikoa aa
prscptly n possible la lino vith the polata krc^sht asst la the >, *54 '
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1* Xa tfca Fs-cyosal to ib e A* d**
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a. That tb vcrisuJ oea^caies a/feiaj op the daooaloilc* mo that there la acre publicity then la the pact bout the kaswlods* of thla grehlcsa cad cheat aesa of the wegr fercrafcle tape eta that do exist, hat vhleh cro es&Aeoa to Boot paenle. Tho purpooa of thla la to pcobst the adrerpe cad Gcftam unwarranted pssada faata that aro jut cat hgr otiaare, Dr. Caith end Dr. Cartier should be kept adrieed >7 other# la the Q. h X, A. ead the asbestos Industry of as/ dsrolepjeoato that *ay boegna kaewo to thaa.
b. That ear deotcre eocssicaally *& talka or loaturos t ismUcmO. cohoola la the genaral ere*.
c. That we * that car dorter a fet adequate cfflllatloa with rer>creh center c rack aa tsranae end other crganlsatlcea 00 that the/ will (et all eraileble infcats*tie* eo thla cad : other cosh subjects.
d. That the ocapoaioa la the aabertoa Industry consider tho foraatioa of tax Institute for Industrial Cheat Diseases with other Blnlng as * exileti on*. In doing this, it v*a ueatlaoed that tha help of Dr. Grefeire of Soeeacunt Sanatoria*, Dr. Burk# of the Lsurcaiiaa, ead ether a be sought.
B Deadunions i
1. It vac agreed that the flrat tlareo (a, b, and e, ahenre) aScold be done, It being under stood, of csutn, that jodfeeai mat bo used la the degree of pertieipatlcaa of ear dealer voder b od e.
fowrer, it vaa the consensus of the group that tho asberteo industry would do well t* arreid identifying itself et thla time vith other ining asceoiatieaa (d, shore) o far aa cheat dleeaeea are oca corned. It vaa pointed out that the prohleeaa ef tho asbestos indus try are ainer aa aeszpared vith those of nany other vlatng indurtrie a, and that euah affiliation nifht tend to identify the aahefts* nlatag Industry with the probl**# of other oialt^ indurtrloe. It v*i felt that thla should be held la abeyeaoo.
eet Tandlrer Ersvn A. X. richer L. C. Esrt
J. f, V. KoreaWr U, 1990