Document JvEEVwameD5wG8pqO8nYVonBe

*Oy 1, 1965 Nr. X. N Binger engineering Supervisor K. X. duPont 4* Momours k Company F. 0. Box 307 Le Forte, Texes' Deer Nr. Singer* X have been asked to forward toxicity and safe handling Information on our fire resistant hydraulic fluid. ^F--y-d--r-a--u--l -1--5--0-.-The question of possible carcinogenesis was brought up. This certainly can be dismissed completely, as we have no reason to believe the components of this compound would have this type of action. We have never had the slightest nmor of this from our custoemrs and certainly no tumors have arisen in cur workers manufacturing the material. Likewise, there have been no reports of any such tumorigenlc notion from the type of moleoules Involved. The animal toxicity report on Fydraul 150 indicates that it is practically innocuous when fed orally to rats, since the animals survived Single doses of 26.5 grans per kilogram with loss of appetite and severe diarrhea as the only toxic effects. The fluid apparently is not absorbed through the unbroken skin of rabbits since this speoles survived doses up to 9*5 grams par kilogram of body weight. Xn rabbit akin sad sys irritation stadias, Fydraul 150 was no mors irritating than s 10 par sent soap solution tsstsd similarly. Xn sssss when workman have accidentally splashed or rubbed fydraul 150 into the eyes, there has been eevera pain out of proportion to the degree of irritation. This it aim!lap to tha situation with moat synthatlc fluids, as mall as with many light petroleum oils. Fhysielens hove meed e 0.5 per cent pontooolno eolation end ophthalmic cortisone acetate eolation to relieve irritation. DSW 018589 STLCOPCB4005133 s- Xn asut vapor inhalation studios, rata survived a six hour exposure to an staospbsre saturated with pydraul 150 vapora at rooa teapsrature. X would not expeet that significant vapor aonoantrationa would ha liberated at temperatures up to 100 7. Baaad on tha aniaal toxicity data and handling experience, our label lnaludaa tha following precautionary information GAtmoMe mm&sm tmummTSL amocAKsoMs Avoid prolonged breathing of vapora or atiLata. Avoid oontaot with ayes or prolonged contact with akin. Xf akin contact occurs, restore by washing with aoap and water, fallowing eye oontaot, flush with water. If clothing becoaea eoakad with fluid, laundar before wearing again. St X ean be of any further aealatanoe, please do not hesitate to let ns know. Sincerely, WSS/ln ocs Nr* K, A, Oareia St. SBBBtt Bally, M. D. Stedioal l&reotor DSW 018590 1afie STLCOPCB4005134