Document JrjmZRgO2aeQExBnZKd0ZaVL6
FILE NAME: Owens Illinois (OWILL)
DATE: 1950-1951 DOC#: OWILL047
DOCUMENT DESCRIPTION: Letters between OWILL & Saranac Labs Related to Contract
OW ENS-ILLINOIS G LA SS COMPANY
G E N ER A L O F F IC E S TOLEDO 1, O H IO
July 24, 1950
Arthur J . Vorwald, U.D. Trudeau L ab o rato ries Saranac Lake, New York
Dear A rt:
I was very m u ch 'in terested in your plans fo r the next symposium
upon pneumoconioses. As soon as the p lan s are la id , I th in k TE"
would be an e x c e lle n t g estu re i f you would pass on the informa
tio n to th e A f r i c a n Academy o f Gen e ra l P ra c tic e .
at
T h irty -fo u rth S tre e t Kansas C ity 2, M issouri., I f they author
ize c r e d i t fo r those luce m yseir tfhoHSfiaTaeinbers, i t w ill help
us in securing the necessary 50 c r e d its .
For your inform ation, to m aintain your membership you are r e q u ired to secure 150 hours c r e d it by attendance a t medical so c i e t i e s and through the deliverance o f papers and a r t i c l e s fo r p u b lication. F ifty additional c re d its can only be attain ed through attendance a t au th o rized sem inars. I hope t h i s gives you enougi inform ation up:>n th e su b je c t.
With k in d e st regards and b e s t w ishes, I am
Sincerely yours
C.F. Shook, M.D.
IDS
Medical D irector
OW ENS-ILLINOIS G LA SS COM PANY
G E N E R A L O F F IC E S TO LED O 1, O H IO
August 15, 1950
A rthur J . Vorvrald, K.D. The Trudeau Foundation Saranac Lake, Hew York Dear Art j
R eceipt i s acknowledged o f your l e t t e r o f August 10 to g e th e r w ith informal contracts.
I have d iscu ssed t h i s m atter w ith B ill Hazard and we both f e e l co n fid en t th a t th e re is a meeting of the minds not only here in Toledo b u t w ith you fo lk s a t Trudeau.
I might add, however, t h a t in my fo u r years we have never sen t any film s to you fo r exam ination w ith a'view to using such in fo rm atio n le g a l l y . Our d ata has been used tw o -fo ld in the p lan t i t aids the p lan t physician on each individual c a s e , w hile we i n Toledo are ab le to m ain tain an o v e r a ll study of a ll of our possible dust hazard occupations.
Thanks a lo t fo r your cooperation and a s sista n c e in t h i s m atter Sincerely- yours
C .F .'Shook, li.D ms
Ijsdical D irector
C. F. Shook, M.B. \ Medical D irector ';\f O w en s-Illin ois .a ss Coupany
Toledo i , Ohio .
Door Charlei*
hjy d aisy i s returning tho contract us duo to th e absence o f Boot ar B r isto l from the x-ray department on aeooaat of illn o sa i s M b f s a lly . I nested to discus the B atter n ith Mjb before o een ittin g M e deportment.
He agree in p rin cip le to the eontr a c t eoneerniag ease filB s forwarded t o a i o n i array b a s is . In survey ex am inations there are always a nuafeer o f sn w ith normal oheete and th e ir x-rays ean be reviewed q u ick ly, o ffse ttin g th e tia e end study nfcieh a s s t be g ita a to problem o a ses. Thus i t ie p o ssib le to keep th e o v e r se ll co st per oase on e survey se r ie s e t a very le v fig u r e , Qian, however, a ease vhich req u ires p articu la r a tten tien far m edleo-legal purposes i s forwarded to u s, e e b e lie v e th a t i t should be handled as a sp ecia l eaae end be b ille d eooordingly, TM i ie our general praotioe w ith other oempsaiea,
1 b e lie v e th a t you w ill concur w ith our view concerning the B a tter. In th at lig h t, the two copies o f the contract arm being returned approved and accepted by u s,
Sinoerely yours
AJVtbw
Boos. (2 )
c
Arthur J . Verwald, K,D. D iroctor
S fit. fi&t &
OTNKS-ILLIHOIS GLASS COMPAHT
c
Toledo 1, Ohio
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Jan u ary 1 , 1950
The Trudeau Foundation P . 0 , Box 551 Saranao Lake, I . Y,
Gentlemen
This m ill confirm our agreement fo r your cervices f o r one year
from th e date hereof
From tim e t o tim e -we w i l l forw ard C hest X-Rays t o you fo r
i n t e r p r e t a t i o n . You w i l l supply a w r itte n statem en t o f your in t e r p r e t a t i o n
of each Chest Case fo r which you w ill b i l l u s $4,00 per Case. A "Chest
Case" i s d efin ed a s th e roentgenogram s o f one p erso n , and may c o n s is t o f
a sin g le film , a se rie s o f film s sent fo r comparative study, a stereo p a ir,
a l a t e r a l , and an oblique I n te r p r e ta tio n s ren d ered a t d if f e r e n t d a te s ,
alth o u g h o f th e same p erso n , w i l l be b i l l e d as s e p a ra te C hest Cases
I f th e above i s in aooord w ith your understanding, please sign
th re e copies o f t h i s l e t t e r a t th e a p p ro p riate plaoe in d ic a te d below, end
r e tu r n two signed c o p ies to u s f o r our f ile s
Very tr u ly yours,
OHEHS-ILLIHOIS CHJLSS COUPAIT
/ s / G. I . Cook A sst, D irector of Purohases
Approved and Aooepted
C b ,_, ^ ; o
1950
THE TRUIK IOUIDATIOI
By / b/ A rth u r J , Vorwald
r~ '* \
Saranac Lake, N. I ,
Dear Doctor Vorwald:
X agree in principle With the contract as subnitted by the Owens-Illinois Glass Company, dated January 1, 1950* However, as mentioned in your note, there must be clarificatio n concerning any special medico-legal cases upon which the company may desire our opinion.
Veiy tru ly yours,
UB:S
iZc~ --
Leonard J . B ristol, M.D., Director, Dept, o f Radiology
THE TRUDEAU FOUNDATION
FOR THE CLINICAL AND EXPERIMENTAL STUDY OF PULMONARY DISEASE
AT SARANAC L A W , N .T .
THE SARANAC LABORATORY
TH E TRUDEAU FOUNDATION THE TRUDEAU SCHOOL
AT TRUOBAU, N .T .
THE DEPARTMENT OP PHYSIOLOGY THE DEPARTMENT OP BIOCHEMISTRY THE DEPARTMENT OP RADIOLOGY THE TRUDEAU LABORATORY
Aagust 10, I960
C. F. Shook, 1U>. Medical Diroetor Owens-Illinois 9 U m Toledo 1, Ohio
CMpojr
Dear Chariest
Mf delay In retaming the eontraot was dee to the absence of Doctor Bristol from the x-ray department on account of illness In bis family. I seated to discesa tbs matter with him before committing bis department.
We agree in principle to the contract concerning ease films forwarded to ns on a survey basis. Xn eerrey sxasinstlQns there re always a nailer of men xrith normal chests and their x-raya can be reviewed qtdckly, offsetting the time and study Tdilob mnst be given to problem cases. Thus it Is possible to beep tbs over-all oest per ease cm a survey series at a very lev figure. I m i , however, a ease sbioh requires particular attention for medico-legal purposos la forvarded te us, se believe that it should be bandied as a speelal ease and be billed accordingly. Ibis is our gemerai praetiee with other oompealea.
I believe that yea trill concur vitti cur view concerning the matter. In that li^rt, the teo copies of the contract arc being returned approved and accepted by as.
8inoerely yours
AJVtbv fines. (2)
Arthur J. Vorvald, K.D. Director
OHHES-ILLIBOIS GLASS COMPAST
c
Toledo 1 , Ohio
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P
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Ja n u ary 1 , 1950
The Trudeau Foundation . P . 0 . Box 551 S aranac Lake, H. Y, Gentleman *
This w ill confirm our agreement fo r your serv ices fo r one y ear from th e date h ere o f.
From tim e t o tim e we w i l l forw ard C h e rt X-Rays t o you f o r i n t e r p r e t a t i o n . You w i l l su p p ly a w r i tte n sta te m e n t o f your i n t e r p r e t a t i o n o f each Chest Case f o r which you w ill b i l l us $4.00 per Case, A "C hert Case" i s defined as the roentgenograms of ons person, and nay: c o n s ist o f a sin g le film , a s e rie s of film s sent fo r com parative study, a ste re o p a ir, a l a t e r a l , and an o b liq u e. I n te r p r e ta tio n s rendered a t d if f e r e n t d a te s, alth o u g h o f th e same p erso n , w i l l be h i l l e d as se p a ra te C hest C ases.
I f th e above i s in accord w ith your understanding, please sign th ree copies o f th i s .l e t t e r a t th e appropriate place in d icated below, and r e tu r n two sig n ed co p ies to us f o r our f i l e s .
Very tr u ly yours, OWEHS-XLLUrOIS GLASS COMPJJT / s / G. W. Cook A sst. D irector of Purehases Approved and Accepted > 1950 TBS TRU1JLUJ FOUXDATIOir By / a / A rth u r J , Torw ald
January 26, 1950
Mr. Villisa J. Meyers Purchasing feat Ovene-Illiaoie Glass Coapaay Bridgeton, Kev Jersey
Dear Mr. Meyers:
Re: Requisition Sc. Lyj Purchase Order So* Dated - January 23, ^SO
Thank you for your authorisation of Jmu a r y 23 in vhich
you hare approved our charge of ii.CO each for the interpretation
of X-rays taken and sent by you cf your eaployees during the
period Fel5ra*r7 1, 1950 to January 31, 1951.
Sincerely yours,
AJViLB
. ,
CC* Fiscal Departaent
Departaent of Radiology
Arthur J. Director K
^
Vorvald, M*D.
January 2D, 1980
Mr* *f.H lsm J* Meyer s Bridgeton Purchasing Agent O e e n a -Z llln o is G lass Company B ridgeton, Be J e rs e y
Dear Mr* Meyers*
Your l e t t e r o f January 11 addressed to th e a tte n tio n o f D oetor G ardner h a s cone t o me f o r a t t e n t i o n . D octor G ardner d ie d suddenly eome t m y e a r s ago.
Us a re p leased to n o te th a t you wish to renew the a rra n g e e e o t covered b y your o rd e r B-8549 o f De cembe r 2 1 , 1948, f o r t h e i n t e r pr e t a t i o n o f x - r i y f ilm s b y th e fou n d atio n * D uring rec en t months, b o a m r , th e Foundation and S asato rlu a have been forced to ra ise i t s fees la accordance w ith increasing co sts and ff> o f f s s t t b s In c r e a s in g o p e ra tin g d e f i c i t o f a l l d e p a rt m ents, in c lu d in g th e D epartm ent o f R ad io lo g y . T h e re fo re , we wish to advise th a t our charge fo r th e type o f a e rrie e rendered h ereto fo re cannot be accompliahed fo r le s s than a |4*00 fee p er film * I t r u s t t b i t i s ag re eab le t o you, and t h a t we way ag ain bene th e pleaaure o f ccrving you*
Sincerely yours
AJVtbv
c. C- f I*--
A rth u r J , V o reald , M.D. D irector
owek-:ILLINOIS GLASS COMPANY
G E N E R A L O F F IC E S TO LE D O 1, O H IO
M. a BEISHLINB FLAJfT IIAHASCI
BRIDGETON, NEW JE R SE Y
VRtrtHT
January 11, 1950
The Edward L. Trudeau F o u n d a tio n of the Trudeau Sanatorium 6 Church S tre e t S a ranac L ake, New York
A t t e n t i o n s Mr. Le&oy U. G a rd n e r, M, D ., D i r e c t o r
Gentlemens
Arrangement fo r the in te rp re ta tin g of X-rays fo r us as covered by our order 3-53^9 of 12/ 21A 8 expires January 3 1, 1950. Charge fo r the service has been $2.50 each.
Being in te re s te d in renewing the above fo r another year beginning w ith F eb ru ary 1, 1950? vrould you p le a se advise i f the $2.50 charge per X-ray s t i l l applies.
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mVENS-IIililNOIS GLASS COMPANY
GENERAL O FFIC ES TOLEDO 1, OHIO
October 25, 1950
Mr. M.C. E aton Norwioh Fharmaoal Company Norwich, New York
Dear ifeli
I have delayed answering your kind in v ita tio n o f June 7, 1950, i n hopes th a t by sows hook o r erook I co u ld schedule a t r i p n e a r Norwich, New York. To date ay p la n s have kep t a s a t a d is ta n c e , b u t we s t i l l have yoor l e t t e r b efo re us and someday, somehow we w ill ag a in spend a n ic e, day to g e th e r .
I do a p p re c ia te th e co n tin u ed i n v it a ti o n s from f r ie n d s o f th e pharm aceutical industry, and I e sp ec ially enjoy continuing cy ed u c atio n o f p ro d u ctio n l i n e s . So one knows what the fu tu re Bay hold and th e b e t te r ideas. I have o f nedie&l su p p lies and equipment, the b e tte r I can f i t in to any *emergenoy" p lan .
A s h o rt tim e ago I s e t w ith Dr. A rthur Vorwald a t Saranao Lake and I had a v ery enjoyable evening w ith him and h is lo v e ly w ife . Both o f them asked t h a t I extend g re e tin g s when n e x t we m et. They are a grand p a ir and I always en jo y being w ith them. A rt has done an e x o e lle n t b i t o f re se a rc h f o r our company and we fee l very close to h is.
I presume th a t I w ill see you a t the mid-year meeting of the American Pharm aoeutioal M anufacturers A sso ciatio n . At th a t tim e we oan co n tin u e where we l e f t o f f .
In th e meantime, th e b e s t o f everything to you as u su a l.
Sinoerely,
C .F. Shook, 1L.D.
IBS
be j Dr. A .J. Vowwald
Medical D ireotor
OWENS-ILLINOIS GLASS COMPANY
GENERAL O FFIC ES TOLEDO 1, OHIO
October 24, 1950
Dr. A .J. Vorwald Saranac Laboratories ? .0 . Box 551 Saranac Lake, New York
Dear Art*
I have your l e t t e r of October 19 and apparently I did not make myself clea r in describing Dr. Sander's lung specimens used fo r demonstration purposes. Apparently Dr. Sanders has the source for he showed us an ex cellen t se rie s and thus our enthusiasm.
Under no circumstances do we want you folks to go to any tro u b le ,'e s p e c ia lly i f someone else is already making these cuts av a ila b le . The next time you see Dr. Sanders, you might ask him what 1 am talk in g about.
Glad the peaches arrived OK. We too enjoy them.
The b est of everything to you and your fine group in Saranac.
Sincerely,
O'ffENS-ILLINOIS GLASS CO.
C.F. Shook, M.D ms
liedical Director
\
October 19. 1950 {Dictated October 17)
C. P. Sbook 1*9 Medical D iractor O w ens-Illinois 61a Coapangr Toledo 1 , Ohio .
Sear Charlia r
As you su g gest. v s v i l l sake erery ffo rt to prepare duplicate sectio n s o f oar p ath ological a a te r la l fo r your u se. The Job 1 rather a s e tie e lc a s and tiae-eansusdng oae. I f only we could a ffo rd so re h elp . The c o st should a c t he too r e st.
The peaches froa th e Soxthm et vers Indeed aaana fToa heacrsxu What a ls e f Vhat ta ste ! Thank you both fo r the headsoae g i f t .
Ve lo o k forward to seein g you soon again. ith kindest regards.
Sincerely yours.
sm ss
OWENS-ILLINOIS GLASS COMPANY
G E N ER A I, O F F IC E S TOLEDO 1, O H IO
Sept. 15, 1950
Dr. A. J . Vorwald Saranac Laboratories Saranac Lake, N. Y.
Dear Art:
I spent yesterday morning with our good frie n d Sanders from Mil waukee, and while with him, he showed me some of those fin e sections of lungs mounted fo r ex h ib itio n purposes. You had several o f them when I was l a s t in Saranac.
I believe th a t a se rie s of these mounts would help m ateria lly in educating not only our medical people, but management as w ell, upon the s ilic o s is su b ject. I think i f your group could devise a s e t including a normal lung, advanced s ilic o s is , tu b ercu lo sis, anthracosis, e t c . > we could s i t down with our people and show them the changes th a t take place w ithin the body.
This is probably an e n tire ly new subject on your p a rt, but yet on the other hand i t may be one th a t somebody else has the answer fo r.
I f the cost was not excessive, I would lik e to buy a se t or two fo r our own use.
Think the m atter over and see i f you can help us.
Sincerely yours,
C.F.SHOOK, K.D, GC
Medical Director
Dear A rt;
J u s t re tu r n e d from another t r i p and found your very i n t e r e s tin g l e t t e r aw aitin g me. I am g la d t h a t the samples and g ifts arrived safely.
IvSadge asked about Emur A bbott. I w rote my good fr ie n d s a t Abbott L ab o rato ries and th e i r re p ly is th a t they never heard of him in s o fa r as th a t Abbott fam ily i s concerned. Dr. Wallace A bbott, th e founder of Abbott L a b o ra to rie s , had only one c h ild , a d au g h ter. Sorry we couldn't give her th e in fo rm atio n she d e s ire d .1
Thanks again fo r ev ery th in g .
S incere!
C.F. Shook, M.D. ms
f l&dical D irector
c. F . Stock, IU ).
Medical D irector Ow e n -Illin o is Gifta Company
Toledo i , Ohio
/
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Dear C hariest
The g la s s blo ck s j u s t f i t our house. Both Mrs. Yorwald
and I a p p re c ia te your th o u g h tfu ln e ss in sending them to u s.
Hov d id you knew o f b u r w ish to have them?
My every good w ish t o you and to Mrs. Shook. I do hope
th a t th is tim e a l l as e ll a f te r leaving the Adirondack.
Both o f us look forward to your next v i s i t .
Sincerely yours
AJYtbw
Ju ly 26, I960
C. F . Shook, M.D. M edical D irecto r Jlucn - I llin o is P .0 , Box 1035-56 Toledo 1 , Ohio
Dear C harles*
I p ro a ised th a t I would send you th e in form ation
w hich we lik e t o hare when m a te r ia l i s se n t to u s fo r
our study and o p in io n .
The attach ed copy nay be u se fu l to y o u .
S in cerely yours
AJVtbw
ft.
o ct Mr. T . 6 H asard
Arthur J . Vorwald D irector
Jane 14, 1950
Mr. V ..G . Hasard In d u stria l R elations D ivision O v e n - Illin o is G lass Company
Ohio
Dear Mr. Hazards
Doctor Vorvald has asked ae to say th a t F riday, Ju ly 14, v l 11 he a convenient tim e fo r your v i s i t and th a t he I s looking forward to th e pleasure o f having you and Doctor Shook w ith u s a t th a t tin e*
Should you w ish me to sa k e any h o t e l r e s e r v a tio n s f o r you, p lease l e t a e know.
Sincerely yours,
LB CC C. T . Shook, K.D.
L ill ia n R. B linn (M rs. A.B.) Executive S ecretary to A rth u r J . Vorw ald, M.D. D irector
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THE SARANAC LABORATORY SARANACLAKE NY=f -- '
WO REPLY YET ODg Rp jp tt - g WOULD FRIDAY JULY 1 4 BE CONVENIENT wifS^YOU FOR DR SHOOKS AND MY VISIT* -
W G HAZARD OWENS ILLINOIS GLASS CObs
U IS S'<
.TBS COUPANT W IU , APPRECIATE 8 0 0 0 ESTIONS FROM IT8 PATRONS CONCERNINO IT8 SERVICE
Joly 28. 1950
C. r . Shook, tf.D. Ovreno-Illinols Glass Company Toledo 1, Chio
Sear Charlie:
Thank, you for yerar l e t t e r of July 2* id the sanples
cf layle vhich arrired thle online.
excellent addition for twr flascaa.
v i l l eke ah
I v i l l infera Doctor B risto l o f the delay v ith regard tc the X-rsy f l i n t on Eay tfcXlnney. Thir i s not too srieras cince Doctor B ristol h?s been orlled hone due to hie sK>ther*B
illneee.
Rrs. Ycrvald end enjoyed helng v ith yen wad Thrs. Shook*e hope that yon w ill Teturn coon aein.
Sincerely yours,
AJTjIS
Arthur J . Torweld. P.S. Director
G E N E R A L O F F IC E S *T O LE D O 1, O H IO
July 24, 1950
Arthur J . Vorwald, M.D. Trudeau L aboratories Saranac Lake, New York
Dear Art
M
I am sending under sep a rate cover two samples o f Kaylo fo r your /
-m
museum* I f you d e sire any o th e r samples, p lease advise me and f
I w ill pass the inform ation on to th e Kaylo D iv isio n . ____ .-- \
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This o rg a n isa tio n i s now the Kaylo D ivision of th e O e n s - I llin o is
^-4'
Glass Company and i s not a p a r t of th e American S tru c tu ra l Products
Company.
I would ap p reciate i t i f you would c a ll Dr. B ris to l and t e l l him \ th a t th ere w ill, be another two weeks' delay in g e ttin g th e X-rays I on Ray McKinney o f our Gas C ity p la n t. Ray i s on th re e weeks' vacation and w ill not re tu rn u n til July 31. At th a t tim e they w ill take the X-rays proposed by Dr. B risto l and send them, t o - y gether with the occupational history, for further study.
I more than enjoyed my b r i e f v i s i t w ith you and your e x c e lle n t s t a f f , and e s p e c ia lly did we enjoy th e evening w ith you and Mrs. Vorwald.
When B ill Hazard re tu rn s from h is v a c a tio n , a f i n a l re p o rt w ill be made and I know t h a t he w i l l cover you a t t h a t tim e.
Thanks again fo r ev ery th in g .
Tilth k in d e st re g ard s and b e s t w ishes, I am
Sincerely yours,
INDUSTRIAL RELATIONS DIVISION
C.F. Shook, M.D. ms ce Mr. W.G. Hazard
Medical D irector
OWENS-ILLINOIS GLASS COMPANY
GENERAL O FFIC E S TOLEDO I,.OHIO
June 15, 1950
Dr. A rthur J . Vorwald Trudeau Foundati on Saranac, New York
Dear A rt:
This morning I re ceiv ed the telegram confirm ing my re se rv a tio n a t M irror Lake Inn fo r fo u r days beginning Ju ly 13. Thanks a l o t .
We w i l l be seeing you on the 14th.
With k in d e st re g ard s to you and the fam ily, I am
Sincerely yours
INDUSTRIAL RELATIONS DIVISION
C.F. Shook, M.D.
JOB
Medical D irector
June 14, 1950
C. ? Shook, K .D ., M edical D ire c to r O v e n s-H lin o l s G lass Company In d u strial R elations D ivision Toledo 1 , Ohio
Dear Doctor Shooks
Doctor Vorvald has been tie d up a l l day v ith v is ito r s to th e L ab o rato ry from W ashington, D .C ., and he h as asked me to reply to your la tte r of June 13.
E a rlie r toda^ I confirmed the date of Ju ly 14 to Mr. H azard. Doetot* V orvald w i l l be v ery happy to see you a t t h a t tim e. ///
V ith reg ard /to h o te l rese rv a tio n s fo r you fo r th a t weekend, a s Doctor Vorvald has term iriated h is membership a t th e Lake P la c id Club, I have rese rv e d a double room w ith tw in beds and fakth f o r you and M rs. Shook a t M irror Lake In n , Lake P la c id , f a r la t e a r r iv a l Thursday n ig h t, Ju ly 13. A number o f our iftLsitors have chosen to sta y a t th e Inn and to r e tu r n t h e r s l The m eals a r e e x c e l le n t . I t i s ra n on th e American p lan ''-f from $10 to $12 p er day p er p erson. I f th is re s e rv a tio n does n o t ap p eal to you, p le a se l e t me know.
Sincerely yours,
Executive Secretary to -
A rth u r J . V orvald, M.D.
/ .
D irector
LB
OWENS-ILLINOIS GLASS COMPANY
G ENERAL O FFIC ES TOLEDO L OHIO
June 13, 150
Dr. Arthur J. Vorwald Trudeau Foundation S aranac, Hew York
Dear A rt:
Undoubtedly your l e t t e r to E ill Hazard is enroute te llin g us th at J u ly 14 would be a good d ate f o r th e m eeting.
Since I an going, out o f town t o n i g h t , .1 would l i k e to g e t o f f my r e q u e s t f o r h o t e l r e s e r v a t i o n s now b e f o r e i t i s t o o l a t e . I f the 14th is th e date s e t, could you arrange for a nice twin-bedded room f o r L rc . Shook and m yself fo r fo u r days at t h a t nic e Lake P l a c i d Club you showed us when l a s t we' were t o g e t h e r .
I f we a r e to o l a t e f o r t h a t ty p e o f r e s e r v a t i o n , do th e b e s t you ca n f o r th e same p e r i o d b u t have them n a rk i t "Hold f o r l a t e a r r i v a l Thu rsd a y n i p h t . 'J u ly i s . " ,,e w i l l be d r i v i n g and you n e v e r can t e l l . One t h i n g we do know and t h e t i s t h a t we would l i k e t o spend th e weekend i n your a r e a and we a s s u r e you we w i l l be no b o th e r to you.
B i l l w i l l w r i t e you r e g a r d i n g what r e s e r v a t i o n s he w ish e s. He w i l l probably have h i s e n t i r e fam ily and w i l l v/ant something i n town.
Any r e s e r v a t i o n t h a t you can make I would a p p r e c i a t e c o n f ir m a tio n providing, of course, our date of the 14th is s a tisfa c to ry . I su rely look forward to seeing you.
n i t h k i n d e s t re g a rd s to you and ycur l o v e l y w ife, I am
Sincerely yours,
lUDUSTBILL H n i T i : U J UIVI3I JU
'j2-**
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Shook, H.D.
Hedical D irector
i
*
TH E TRUDEAU FOUNDATION
FOR THE C LIN IC A L A N D EXPERIM ENTAL STUDY OF PULMONARY DISEASE
AT SARANAC LA KE, N .Y .
THE SARANAC LABORATORY
THE TRUDEAU FOUNDATION. THE TRUDEAU SCHOOL
AT TRUDEAU , N .V .
THE DEPARTMENT OF PHYSIOLOGY THE DEPARTMENT OF BIOCHEMISTRY THE DEPARTMENT OF RADIOLOGY THE TRUDEAU LABORATORY
June 15, 1950
Liable Glass Vineland, Sew Jersey
Attention* Mr. B. . Eiabark Purchasing Department
Ret ?.0. 31-3464
Gentlemen*
Vita reference to your letter of June 8, & charge in accordance vith our contractual agr<*sent of <00 per chest case at a given date was not Bade in the instance of the X-ray filas of Mr. Edmund Powell* These filas had been read by the X-ray Bepartaent preYioualy and a charge was made for the BarTies at that tine* Ve Bade a flat charge of $4*00 for a review of the fills in May and there will be no further charge for that sendee.
e trust that this will clarify the Batter to your satis faction.
Sincerely yours,
Arthur J. Yorwald, K*D. Director
AJViLB
CC: Mr. Clarence Vagner fiscal Department - Trudeau
THE TRUDEAU FOUNDATION
FOR
THE CLINICAL AND EXPERIMENTAL STUDY OF PULMONARY DISEASE
AT SARANAC LAKE N .T .
THE SARANAC LABORATORY THE TRUDEAU FOUNDATION THE TRUDEAU SCHOOL
AT TRUOKAU, N .T .
THE DEPARTMENT OF PHYSIOLOGY THE DEPARTMENT O F BIOCHEMISTRY THE DEPARTMENT OF RADIOLOGY THE TRUDEAU LABORATORY
June 15, 1950
Liable* Gle.es Vineland Sew Je rse y
A ttention* Mr. B. . KUbark Purchasing Department
Be* ?.C . 31-3464
Geutlesea*
ith reference to your l e t t e r c June 5, & charge In Accordance w ith our c o n tra c tu a l agreement o f $4*00 p er ch est case a t a given date v*a h o t made in th ? in sta n c e o f the X-rsy n i c e of Kr. H&iund Pow ell, th ese film s had been read by the S-ray DepartAeut j>r*vioualy Lrtd a charge vae made f o r the se r
v ic e a t th a t time Ve m*de & f i s t charge of $4.00 f o r a review
o f tae f i l a a in'H ay and there w ill be no fu rth e r charge fo r t h a t service.
we t r u s t th a t t h i s w ill c la r if y the s e t t e r to your sct i e faction.
Sineersly yours,
A rthur J . V orsald, K.B. D irecto r
AJTiIS
(X: Mr. Clarence Vagner fiscal Department - Trudeau
THE TRUDEAU FOUNDATION
FOR THE CLINICAL AND EXPERIMENTAL STUDY O F PULMONARY DISEASE
SARANAC LABORATORY
TRUDEAU LABORATORY TRUDEAU SCHOOL
Way 31, 1950
DEPARTMENT OF BIOCHEMISTRY
d epa r tm en t o f physiology d epa r tm en t o f radiology
In Ac c o u n t W ith
Hac a p itu la tio n o f film s read during the Month o f May, 1950:
Kimble Glass Company O w ens-Illinois G lass Company O w ens-Illinois Glass Company
Vineland, H. J . 1 0 C lario n . Pa* 7
S a y re v illo , N .J. 2.
44*00 $4.00 " 286.0(0 " -6.00
10
440.00
Distribution: jDrig. and Dup. to Owens-Ill. ^Copy for M r s . Blinn Copy for Fiscal Dept.
Glass
P L E A S E REMIT T O : t h e e . l . t r u d e a u f o u n d a t io n , f is c a l d e p a r t m e n t , t r u d e a u , n e w y o r k i:
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OWENS-ILLINOIS GLASS COM PANY
G E N E R A L O F F IC E S TO LED O 1, O H IO
June 20, 1949
A rthur J . Vorwald, M.D., D irecto r The Trudeau Foundation Saranac Lake, New York
Dear A rt:
R eceipt i s acknowledged of your very kind l e t t e r of June 10, tog eth er w ith the Annual Report o f the Trudeau Sanatorium and Foundation. I alread y had th e o p p o rtu n ity o f review ing t h i s re p o rt, and now I can add i t to ny own l i b r a r y .
This is a most unusual re p o rt in th a t i t is in te re stin g as well as i n s tr u c tiv e . Most r e p o rts , as you know, are f u l l o f s t a t i s t i c s and as a r e s u lt are hard re a d in g . Thanks a l o t .
Tilth k in d e st regards to you and yours, I am
Sincerely yours,
C.F. Shook, M.D. ms
Medical D irector
C. F. Shook, H.D. liedioal D irector A aerioan S tru c tu ra l P roducts Co. P . 0 . Box 1035-36 Tolsdo 1 , Ohio
Dear Doctor Shook*
The Annual Report o f th e Trudeau Sanatorium and
Foundation has J u s t re c e n tly been published. Being
K in d fu l o f your I n te r e s t in th e work o f th e Foundation
which is covered in th e la s t h a lf o f th e brochure, 1
wanted you to be among th e f i r e t to re c e iv e a copy.
I hope, Doctor Shook, th a t th e b r ie f expose' o f our
reeearohes w ill be of in te re s t to you.
Sineerely yours
AJY:hw Btao.
A rthur J . Yorwald, K.D. D irector
U a iW i O fr kTclcgram or Cable gram unless Its de terred chatscter Is In dlcsted by a suitable : symbol above o r p r e *
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,, THE SARANAC LABORATORY SARANAC LAKE NY=
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tTHANKS YOUR LETTER 11/19 LOOKING FORWARD SEEING YOU ANDf
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TOM DU R K A N WEDNESDA Y ; j
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W Q HAZARD OWENS ILLIN O IS GLASS COMPANY
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October 25, 19SI
Mr. V. G. Haxard . .. Industrial Halations D ivision O w ens-Illinois Glees Caapany Toledo 1 , Ohio
S n r B ill*
Wednesday, Hovaeber 28 tr ill c o lt as fin e) in fa ct I aa Tory glad you find i t p ossible to delay your v is it hero u n til then. Uj calendar th is south is an exceedingly busy one. Soreaber 13 I leoture in Bee York City and then go on to Pittsburgh for the Industrial Hygiene Foundation nestings on the 14th sad 15th. Perhaps ne w ill n est th ere.
With kindest personal regards.
Slnoerely yours,
AJY*lr
set Mr, Durkan Mr. "Urban
Arthur J . Vorwald, K.D. D irector, The Trudeau Foundation end The Saranac Laboratory
O'WENS-UjIjINOIS G IA SS COMPANY
G EN ER A L O F F IC E S TOLEDO 1, OHIO
October 23, 1951
Dr. A. J . Vorwald The Saranac Laboratory Saranac Lake, New York
Dear Art:
Thanks fo r your telegram . I envy you your tr ip to San Francisco--and hope you have a wonderful time.
You mentioned November 9-12 as p ossible dates for our v i s i t . The 12th would be a l l rig h t, except for a purely per sonal angle--i t means leaving hone a t noon on Sunday. I am wondering whether you could make i t the 13th. I f th is doesn't work out w ith you, how would November 28 be?
Personal regards.
Sincerely yours,
V.'.G.Hazard: 1C
INDUSTRIAL RELATIONS DIVISION
October 2 2 , 1951
Mr. W. 0 Hazard In d u strial B elationa D ivision O w ens-Illinois G lass Company Toledo 1 , Ohio
Dear B ills
In reply to your le t t e r o f October 19, I an Tory sorry indeed th a t other o b lig a tio n s make i t im possible to meet mith you here on eith er October SO or Horasber 5 U nfortunately, I mast be in San Francisco on October 26 end i t looks near as though I may n ot g e t book to Saranac Lake u n til November 8 . Consequently, I suggested in sgr telegram to you today, November 9 , 10, 12, or any tim e during the meek o f November 26 I tr u st th a t one o f th ese days can be worked in to your schedule.
I am very sorry, B ill, th a t I cannot arrange fo r an e a r lie r m eeting. P lease l e t me know m hetherany o f the dates mentioned m ill be convenient fo r you.
With k in d est personal regards,
Sincerely yours,
AJVilr
Arthur J . Vormald, K.D. D irector, The Trudeau Foundation and The Saranac Laboratory
OWENS-ILLINOIS GLASS COMPANY
G E N ER A L O F F IC E S TOLEDO 1, OHIO
October 19, 1951
Dr. A. J . Vorwald The Saranac Laboratory Saranac Lake, New York Dear Art
Some time ago we had correspondence with Tom Durkan about his dust counts and other analyses made e a r lie r th is year when he and Mr. Urban v is ite d our S ay re v ille, New Jersey p la n t. We've been looking fo r a chance to get together with you and him so we can c la r ify our understanding of the methods th a t were used, and their significance.
I 'm wondering i f I could see you and Tom a t Saranac Monday, November 5 I f th is is not su ita b le fo r you, perhaps we could make i t Tuesday, October 30. I 'd appreciate i t i f you could send me a wire so I can t i e th is v i s i t in w ith a t r ip to some of our plants in the east.
I f n e ith e r date i s convenient, l e t me know, and we can work out another one.
Personal regards. Sincerely yours,
INDUSTRIAL RELATIONS DIVISION
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Hovember 1 9 , 1951
Ifr. W, 6. Hasard Industrial Relations Dirision Owens-Illinois Glass Compasy Toledo 1, Ohio
Dear Bill*
I m a t apologias fo r the delay in replying to yoor l e t t e r of August 7 regarding the oceurrenoe of kidney stones in in d u stria l workers exposed to lia s dust* We hare searched our f i le s and haws looked 19 a number of references b ut have not been successful In obtaining sp ecific information of great value. There is , however, in d ire c t evidence, derived frost the Portland cement industry and from the gypsun industry, th a t exposure to dust containing lia s i s not significantly responsible for the formation of kidney stones,
Ths Portland Cement Association, which includes most of the p lants in th s cement industry, keeps a careful record of accidents and illn e sse s of the approximately 50,000 employees o f the cement p la n ts. Although ths A ssociation's tabulation does not mention kidney stones sp e c ific a lly , i t i s shown in the la t e s t report ws have in our f i le s (1941) th a t th s frequency ra ts of diseases o f the genito-urinary system ( other than c ertain ones, lik e n e p h ritis, which are reported separately) was 2,5 fo r the cement industry as compared with 2,4 for a l l in d u stries reporting to the Public Health Servios, From th is comparison one would in fe r th a t dusts in esmsnt p lan ts, of which oalcium i s usually the predominating component, are not an important eause of kidney stones.
As a p a rt o f our Investigation of the gypsum industry, in which calcine sulphate I s the p rincipal constituent o f th e atmos pheric d u st, we had occasion to make physical examinations of mere than 100 employees o f a c ertain p la n t. The report o f the stuty contains the statement th a t "no evidence of pathological changes was found which could be a ttrib u te d to ths speeiflo action of gypsmm d u st," Although kidney stones were not mentioned in 'th e . report, i t seems lik e ly th a t had there been an unusual occurrence of kidney stones among the man examined, th a t fa c t would have been brought out by the in terrogation of the men during the course of the physical examination.
In regard to the e ffe c t on the oalcium balance of drinking
r . W* G. Hazard
2-
Horwaber 1 7 , 1951
carbonated beverages we hate no inform ation. He b elieve i t to be u n lik ely , however, th a t ordinary aaounte o f carbonated beverage# would e ffe c t the e&lciua balance
He are looking forward to your v is it here next week.
H lth every b est w ish,
Sincerely yours,
AJYjlr
Arthur J , Vorwald, H.D. D irector, The Trudeau Foundation and The Saranac Laboratory
OWENS-ILLINOIS GLASS COMPANY
GENERAL OFFICES TOLEDO 1, OHIO
J
August 7, 1951
Dr. Arthur J . Vorwald, Director The Saranac Laboratory Saranac Lake, New York
Dear Arts
At one of our plants recently four men suffered kidney .stone attacks during an interval of a couple of days or so. "Everything of an in d u strial nature th a t might have contributed to these attacks was investigated, but the fin a l conclusion was th at the four occurred as a coincidence.
One of the physicians consulted, however, has put fo rth the p o ssib ility th a t breathing lime dust might upset the calcium balance of the body and contribute to the formation of kidney stones. The plant uses lime as a raw m aterial and there i s a moderate exposure to lime dust--although we don't know as yet whether any of the four men involved had th is exposure or not.
Has any work been published showing whether inhalation of lime dust i s lik e ly to re su lt in kidney stones? I don't believe th is was discussed in the cement-dust paper published by Dr. Gardner and others in 1939* but there may be something of more recent date th at we have missed.
The suggestion was also made th at the drinking of coca-cola and other carbonated beverages might have had a bearing on the calcium balance. The plant recently in sta lle d so ft drink vending machines and they have been popular during the recent warm summer weather.
Any comments you have on these questions w ill be very welcome.
Sincerely yours,
W.G.BasardiU
INDUSTRIAL RELATIONS DIVISION
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Mr H i l l * * 6 . Haaard In d u stria l R*l*tion* D ivision O w e n s-Illin o is 61* m Cowpany Toledo 1, Ohio
Dear B ill
In aeoordanee w ith the request is your le tte r of September 17, we have to d a y in s tr u c te d our F is c a l Department to scad th e recap of oharges fo r reading chest x-ray fil* e , lis te d aooording to p la n t lo catio n , d ire c tly to you instead e f to your In te rn a l Audit Department,
llith every b est wish,
Sinoerely yours,
A JV tlr oes' Fisoal
A rth u r J . Torw ald, H,D. D ire c to r, The Trudeau Foundation and The Saranac Laboratory
OWENS-ILLINOIS GLASS COMPANY
GENERAL O FFIC ES TOLEDO 1, OHIO
September 17, 1951
Dr. A. J . Vorwald, D irector The Saranac Laboratory Saranac Lake, New York
Dear Art:
For some time the Trudeau Foundation has been sending us a recap of charges fo r reading chest X-ray film s lis te d according to p la n t lo c a tio n . Some time in the p a st, apparently, th e f is c a l department of the Foundation was in s tru c te d to address these r e caps a tte n tio n of our In te rn a l Audit Department. I t would be a convenience to us i f these recaps were sent to the a tte n tio n of the w r ite r . We'd ap p reciate i t i f you could pass t h i s suggestion on to the people involved.
Personal regards.
Sincerely yours,
W.G.HazardjM
INDUSTRIAL RELATIONS DIVISION
A p ril 6 , 1951
Mr. M. G. H azard Oren s - I l l i n o i s G lass Coupangr In d u strial Eelatton E ivieion T oledo I t Ohio
Pear B ill:
I n acco rd an ce v i t h j o u r r e q u e s t o f A p ril 5
ve a r e hn^rrr indeed to fo rw ard to ycra, u n d er s e p a r a te
cover, th re e copies o f th e r e p r in t on B x p erieen tal '
Studies o f A abestosis.
W ith every b e s t w ish.
Sincerely yours,
urns
Arthur J . form al d., M.P. P ire c to r
CC: K iss Eagan: P le a s e n a i l 3 r e p r i n t s to Mr. H azard.
OWENS-ILLINOIS GLASS COMPANY
GEN ER A L O F F IC E S TOLEDO 1, OHIO
A pril 5, 1951
Dr. Arthur J . Vorwald, D irector The Saranac L aboratory Saranac Lake, .New York
Dear Arts
Do you have e x tra r e p r in ts o f your a sb e sto sis paper th a t appeared in th e January Archives of I n d u s tr ia l Hygiene and Occupational Medicine? I f so, we'd a p p reciate your sending us' a couple of copies.
Sincerely yours,
Y/.G.HazardsM
INDUSTRIAL RELATIONS DIVISION
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ftfenay 16 1951
Hy. It' i . Sayera PertiiBslaNC Oveas-XlliaoiB. S lsss Csspaay Bridgeton* JSfw ieresy
Dm ? Hr. Jfeyerei
l a reply te year le tta r o f K tn a r r 8, ve t n
p leased to knee th a t you wiah to renew th crraagenent
etrrered hy your Purchase O rier B-379 ^ J a u 7 2% 195 .
fo r the la te ry re ta tle a of chart reent^snograne by the
Jeundrtiou. The greeta c a t, uhich tonalaated a* o f
January 3* . 1951. o f 1&,3w per ease per d ate o f f l l a
I s ag ree1M 1 t o o e e u a
nay leaae as order reeewlJ
our M rrlc * i f a r another yuer b eg ia n i^ Pefcrasxy 1 1951
&t the eene ra te.
1 an ereertlojfly eoxsy about the dale? la w reply
hot a anther o f thing Including * abort etey ha the hospital
m de I t Impossible fa r m to handle *y rnrreiponrtimoe prceptly-
1 tru st the delay hee oaaeed you no great Ineearenl**** B lneerely yauca,
Arthur J . Tonrald. K.D. D irector, Sha tm deau iw a d a tlm end fha S a m ie laboratory im a CCi Leonard 2 . B r ia to l, K.B* Head, Department o f Ba&iolegy
fla o a l O ffice
OWENS-ILLINOIS GLASS COMPANY
G EN ER A L O FF IC E S *TOLEDO L O H IO
M. PGU.NBTEHIASNHAXSEJKNB
BRID G ETO N , N EW JE R S E Y
F ebruary 8, 1951
The Edward L. Trudeau F o u n d atio n of the Trudeau Sanatorium 6 Church S tre e t S aranac Lake, New York
A tte n tio n : Mr. A rthur J . Vorwald K. D. D ir e c to r
Gentlemen:
Ja n u a ry l'6 th , we w rote you making re f e r e n c e to our purchase order B-379 of January 23, 1950 covering in te rp re tin g '' X -rays tak en by us and se n t to you which expyied January 3 1 s t, 1951 and in q u ire d i f charges of 3 ^.0 0 each would ap p ly to re n e w a l`o f arrangem ent fo r an o th e r y e a r 's p erio d beginning w ith F eb ru ary 1, 1951 or i f n o t, ju s t what the c o st would' be.
As we would l i k e to send you ar o rd e " renew ing above s e r v ic e s fo r a n o th e r y e a r a s "soon as we h e a r from you, an e a rly re p ly would be a p p re c ia te d .
Yours very tr u ly ,
CEiS-ILLIN O IS GLASS COMPANY
TCmJMeyers/mdj
y
BRIDGETON PIP.CHASING AGENT
OWENS-ILLINOIS GLASS COMPANY
G E N E R A L O F F IC E S TO LED O 1, O H IO
M. PGU.NBTEMIASNHACUCNNH
BRIDGETON. NEW JER SEY
January 16, 1951
The Edward L. Trudeau Foundation of the Trudeau Sanatorium 6 Church S tre e t Saranac Lake, New York
A tte n tio n : Mr. A rthur J . Vorwald M. D. D ire c to r
G entlem en:
Arrangement covered by our purchase order B-379 o f January 23rd, 1950, fo r the in te r p r e ta tin g of x -ray s taken by us and sen t to you of employees of ours e x p ire s January 3 1 st, 1951.
C harges f o r th e above were $*+.00 e a c h .
At your convenience, would you p lease ad v ise i f you would be ag re e a b le to renewing o f th is arrangem ent fo r another y e a r's period beginning w ith February 1 s t, 1951? and i f co st w ill be the same.
Yours very tr u ly ,
OWENS-ILLINOIS GLASS COMPANY'
Wm.JlMeyers/hb
32TERXM REPORT RBGARDIlG THE BIQLQGICAL ACTIVITY
CP KAYLO DUST
to the Owens-Illinois Glass Company
Toledo, Ohio
by Too Saranac Laboratory Saranac Lake, Herr York
January 1, 1950 (The re p o rt has reference to re s u lts of studies up to
Horeaber 1, 1949)
Submitted by;
Arthur J Vorwald, M.D., D irector The Edward L. Trudeau Foundation
In cooperation with;
P h ilip C* P r a tt, t*Q* Tacce.s IL Durksn, M.S* Anthony B Dolakont Edward C. J . Urban, 11.
This interim report, is e sse n tia lly a supplement to the previous re p o rt dated A pril 29, 1949* I t is submitted a t th is tin s in accor dance w ith a plan to issue rep o rts a t in terv ale of about six months.
In the in te r e s t of b rev ity general statem ents as to the methods used, and purposes of each phase cf the experiments under ray ere omitted and the reader is referred to the preceding report fo r d is cussions of these points* I t may be stated th a t the conduct of the experiment has been maintained as i t was in e a r lie r stages, and th a t dust counts during the in te rv a l 3ince th9 l a s t re p o rt have averaged 179 m illio n p a rtic le s per cubic foot of air*
In general, the observations cade over the past six months conform to those noted previously. However, only te n ta tiv e conclusions are warranted a t th is time. I t seems clea r th a t only a f te r a l l animals have been examined a t the end of the f u l l exposure can the re s u lts b9 evalu ated*
The re s u lts to date are presented in tab les as in the previous report* C ertain comments concerning each ta b le follow :
Table 1 (Compare with Table 3 .) In the in te rv a l since the l a s t re p o rt, four additional experimental animc.ls on
being sa c rific e d have shown spreading of th e ir lesions while the con tro ls have consistently revealed healing or healed lesions. Others of the experimental group have fa ile d to show evidence cf spread. While the observations over this period suggest a slig h tly adverse influence of th e dust on the course cf the tuberculous in fec tio n , the
evidence is by no means conclusive, and only subsequent developments and a survey of the re s u lts in the e n tire series of animals can pro** vide a basis fo r a positive statement as to the influence of Kaylo on a simultaneous tuberculous infection.
Table 2. (Compare with Table. 3) Two of the three animals in phase I (in dust 2 months a f te r infection) of the re
activ atio n experiment which were k ille d a fte r 12 months in the dust room showed gross evidence of spreading disease. This observation re mains to be oonfirmed by microscopic study. In the other two phases (in dust 4 months and 6 months ifter infection),no spreads have been noted. Here, too, the evidence is obviously incomplete and does not warrant evaluation a t th is time.
Table 3. (Compare with Tables 1 and 2.) Ho spreading disease has been noted in the six animals k ille d since the la s t re
p o rt. The course of the infection in the controls is thus seen to be in aocord with previous experience.
Table 4 . (Compare with Table 5 .) The table reveals th a t the animals sacrificed or dying a fte r dust exposure of eleven
or more months have co nsistently harbored spreading lesio n s. While some of these are yet to be confirmed m icroscopically, the consistency of the findings suggests rather strongly that under those conditions (infec tio n in itia te d a f te r 3 months of dust exposure) Kaylo has a d is tin c tly adverse influence on the course of the disease.
Table 5 (Canpare witii Table 4 .) The oontrol animals again reveal th a t the infection is f ollovriag i t s usual
course* One animal* k ille d a t 10 months a f te r in fe c tio n , showed s lig h t microscopic evidence of spreading disease* As noted in the previous re p o rt, i t is not uncommon fo r an occasional control animal to develop progressive disease following th is type of infection*
In view of the above findings and fo r purposes of th is re p o rt, i t seems appropriate to present fo r comparison the chemical and petrographic analyses of Kaylo and of long f ib e r asbestos (Table 6).
CCMLSHT At the present time the evidence sugg9s t 3 th a t Kaylo dust m y have a s lig h tly adverse e ffe c t upon tuberculous infection* This e ffe c t is by no means as pronounced as th a t of quartz, since sim ilar experiments with quartz re s u lt in progressive spreading of the lesions in v irtu a lly a l l animals a f te r 8 or more months of exposure. The lesions in animals exposed to quartz dust are usually s u ffic ie n tly extensive to cause death of some animals in the period from 12 to 15 months* The fu tu re course of the lesions in the present experiment cannot be predicted* They may heal during the next 9 months, but i t is f e l t somewhat more lik e ly th a t animals to be sac rificed w ill shew an increasing incidence of spreading disease*
-5-
EAYLO + ?.x 5ILTJLIMEOS
inim al dumber
4 /; i
V
( 2 6
3 ' 5
24 25 10 ( 7 / ; 8
so
14 22
1 s
: 13 28
(11
12
17 20 ' 15 ] 6
Mode Of
Death
Duration.
Eronchial
Lungs Nodes
`i r o s a ____________
Eep&txc Lymph
Spleen L iver Nodo
j _______ S lioroscopio
Dron-
Sep&tic
chial
Lymph
Lungs Nodes Spleen L iv er Node
D I - I / 2 mo. pn + +
0
0
0
Tissue autolyzed
K
2 mo.
0
0
*>
* +
+
V
K 2 mo.
+
0
0
p'r
4*
*f
n-
r
D 3~o/4 mo* (pn?) +
K 4 mo.
+
K 4 mo.
++
D 4- 1 /2 mo* (on?) f
0
0
0
.
pa 0
0
0
0
0
0
'
+ 00
0
0.
0 0 * -+ +
++* *
pn
0 0 > ? 4.*.
D
5 - l / s mo. (pn?)
D G so*
pn + >
l
6 iao*
0
K
8n mo.
+. i-
i
D
6+ mo. fpn + ?
D
7 mo.
pn + f
D
7-2 /3 mo, 1 pn ?
I
K
G mo.
3 +
0
0
0
*
000
0
0
0
000
000
000
0
0
v
pn 0
0
0
Tissue autolyzed >
;0
-
000
+
+
0
0. *
pn 0
000
Tissue autolyzed
Tissue autolyzed
4.*;*
4.
Ci
<
K
8 mo*
H -*
D
8- I /2 mo. 1 *4.
' K 12 mo.
! 1 ++! +
00
*5* +
*
r
+
f *'"?
*T*
*- 0
+++
--N
+.
+:-
*:
K . 12 mo.
D
13- 2/3 iuoj 0 0
1
D 14 mo.
pn 0 0
0
0
0
0
0
0
0
0
; + *+ i
0
0
s'-
K 15 mo. K 15 mo.
*
b
4*4*
0
00
0
0
c
I
7 rem ain f o r aub sequen-; stu d y
Table 2 DUST * Ri REACTI7AT10T
Mode
Animal of
Duration
Number Death Infection Dust
Lungs
Bron chial Nodos
Gross
LiSpleen vor
Hepatic Lymph Node
Lungs
Microscolio
Bron
chial
Li-
lodeg Spleen ver
Eepati Lympl Node
In dust 2 mo. after infection
47 D
2-1/4 mo. 1 /4 mo. p n
0
0
0
*
"T
*> +
it
34 D
3-l/S mo. I-I/3 mo, }*
+
0
0
0
Tissue autolysed
(31 K
(
( 32 E
4 mo. 4 mo.
2 mo 2 mo.
s-
+
0
0
+
0
0
>
+
+
+
00
0
00
*
( 35 E
6 mo
(
( 36
K
6 mo.
4 mo. . +
4 mo.
+
0
0
0
+
0
0
0
+
0
0
+
00
0
( 37
(
( 38
( 33
(
( 39
(
( 40
K 10 mo. K 10 mo. K 14 mo. K 14 mo, K 14 mo.
8 mo. 8 mo. 12 mo. 12 m o 0 12 mo.
4-
*
0
0
0
+
+
Q
0
0
0;
+
i
i
+
->
0
0
0t
\
++
0
0
1
1
j + +
0
0
0
t>
In dust 4 mo , after infcction
00
0
00
-
( 45 ! ( 48
( 41
(
( 42
K
8 mo.
K
8 mo.
E 12 me.
S 12 mo.
51
49
50 ; 52
53
54
D 11 da. D 10 mo. K 10 mo. K 10 mo. r 14 mo. K 14 mo.
4 mo.
0
c
i 0
0
00
"r
4 mo.
r
8 mo.
+
0
0
+
0
1
?
0
0
0j
V
00
0
C0
0
t
3 mo ,
4.
0
0
0
i *
*
00
0
1
In
dust 6 mo ,
after
infectin
tf f
s
0
0 .0
0
c
0 Tissue o.utolyzed
4 mo. 4 mo. 4 mo.
*)*
0
0
0 58 + +
+
*
c
0
\
1 +
*'
*
c
tI
V
8 mo. 8 mo.
! ...
<
c
>
0
0
01
(
0
00
0
00
0
*
'r
+
Tabla 3 INFECTION CONTROLS TO GROUPS I AND I I
aimai caber
ode of
Death
Duration
C-rc so
Bron
Hepatic
chial
Lymph
Lunge Nodes Spleen L iver Node
liioroscopic
Bron-
Hepatic
ohial
Lymph
Lunge Nodes Spleen L iver Node
62
D l "l / 2 mo.
4
0
0
0
Tisnue autolyzed
5?
X 2 mo*
>
0
0
0
4* *>
+
4-
5-
58
X 2 mo.
++
0
0
0
b +
+*
0
0 0
CO
59
X 4 mo.
60
X 4 no.
63
X 6 HO,
b +
0
0
+
+
0
+
++
0
0
0
0
0
bb
+
>
*
+
*
0
0
0
64
K 6 mo.
JL
0
0
0
0
0
0
0
73 . D 6- I /2 mo.
A 4* 4* 4- ;
++
++*
--
37
D 6~2/3 mo. pn ? 4*
0
0
\
<*7t- ssue
autolyzed
1[
65
K 8 mo.
*$ V -
0
00
:
0
0
0
0
36
K 8 mo.
+ b 0
00
!* 0
0 .0
0
88
D g - l / 2 mo. +
f
0
00
Ti ssue autolyzed
61
iv 10 mo.
0
-r
0
00
i t
0
0
0
0
74
K 10 mo.
0
0
I +
.1,
83
D 10-1/2 mo. ! +
V
0
0
0
\ Tissue e.utolysecl
89
X 12 mo.
90
K 12 mo.
67
X 14 mo.
E 14 mo.
S9
E 15 mo.
70
K 15 mo.
4'
r
0
0
0
;
++
0
i
0
0
b 4-
0
0
"r
+ + 0 0 0 iC
t
**r
1
0
0
0
1
si
+
0
.0
0
0
0
0
->
0
0
D 2 died K k ille d fo r sampling Pn in te r c u r r e n t pneumonia 0 z no tuberculous le sio n s seen
- healing or healed tu b e rc le s sc a tte re d is o la te d spreading r many sp rea d in g tu b e r c le s = co nfluent T uberculosis
Tibere m icro sco p ic o b s e n c tiis n s arc n e t re c o rd e d , h is to lo g ic p r e p a r a t i o n s h&vs n o t b e e r ccriolo i'S'i. u n l e r r cth sirrls-* r i o t e d .
r
*
IEAT10 3 EDITHS + R:. I t!'eoiigsi
iio do
aimal of Humber Death
i
Gross
oroscopi c
Broa-
H ep atic
Bren-
Eopct:
Emration _}
dual
L i- Lymph
ohial
L i- Lye:
Dust Infection}L ungs Hodes Spleen v e r Eode Lungs Hcdes Spleen -TOT IToce
107 K 2 no. )
108
TIV*
6 mo c
) )
)
109 K 3 mo. )
110
y
)) 2 cio. )
) 1 1 1 K 2 mo. )
91 D 4 mo, au.tolysed
1 mo.
( 92 1: 5 mo.
2 mo.
I
i }l'o in f e c tio n 1 | See te x t
5t
E 1 t jpnO +
\
| pn + +
! 9S
! 04
; 95 s 6* 07
1; 5 mo. E 7 mo, K 7 me.
1; S mo. ri*. 9 mo.
2 mo. !6 +
.ih.
4 mo. i +*r
*!
f
4 mo. \ ++
*
S
6 mo.
! *+ i
-
\
5 mo* | +
-!
114 . i) 10 mo.
7 mo. |p n ++ -i*
105 112 \ 11S ' 98 ( 106 115 .99 100
V 10-3/4
1: 11 me.
K 11 rao,, T 13 me. K 13 mo. D 14-1/2 K 15 mo. L 15 mo.
7-. 3 /4 8 mo* 8 mo, 10 mo. 10 mo. 11- 1/2 12 mo. 12 mo.
[ pn * 1I '
{ <r
it f +
i ++
I t f
j +++
S1 ! *i**r 1
0 r,
0 rV> 00 00 0r 00
Qe
0c
0c
0
r.
V
00 Q .c
cc
00 a0
0 pn 0
v
000
( fat)
i pn i
f .L k j
0 0 *v .U. 0 0 0
V 000 00 000
000
on
0 0 0 Ur\
> t
7.*S- "U3 an to ly sed
0
00
r:
w 0
*
+'
J.
t
c! f {
0 0 1.
Somo le sio n ." h e a le d
"able 5 INFECTION COHraOLS TO GSOTJ? 17
Uiixaal umber
Mode of
Death
Duration
Gx'oss
Bran
Hopatic
chial
Lymph
Lungs Nodes Spleen L iver lo d e
ii croscopio
Bron
Hep a t
chial
Lynn
Lungs Nodes Spleen L iver lode
; 121 K 2 mos.
*r
0
0
t* ++
4 0
f
( 122
K 2 mos.
0
0
*
v **4*
+0
4*
127
D 4 nos.
pn + JL
0
0
0
Tissue autolysed
( 123
E 4 mos.
+
0
0
+ 0
0
0
4*
( 124 ; 125
S 4 mos. K 6 mos.
4* +
0
j. L
0
0
0
0
i-
4-
0
r
!-
0
0
0
' 126
K 6 mos.
+
4*
0
0. 0
0
0
0
0
0
132
D 6~2/o mos* +
0
0
0
0
0
0
0
145
D 7<- mos. pa + ?
0
' 128
K 8 mo.
r
U.
0
0
0
0
Tissue aut olyzed
o
0
r.
0
( 129
K 8 H00
f* *
0
0
0
0
c
0
137
D 3-1/2 mo* pn + i-
0
0
0
Tissue sutolysed
; iso
i
i 151
; 133
K 10 mo. K 10 mo. K 12 mo.
*
4-
0
0
*
a.
0
0
+
+
+
0
0
0
r
0
0
-
> V
v
0
c
+
i34
E 12 moc
.K
0
0
0
i
P remain
K3Tt
D a died
E - k ille d for sampling
Pn - in te r c u r r e n t pneumonia
0 s no tuberculous lesio n s seen
'* s' h ea lin g or healed tu b e rc le s s scattered iso lated spreading tubercl s many spreading tu b e rc le s - confluent tuberculosis
Tihen m icroscopic cb s e rra tio n r, are not recorded, liis ti lo g ic p re p a ra tio n s hare; n e t bssr. cc p le te d . u n less otherw ise s ta te d .
I able- 6
MALTS ES CP KAYLC (as received)
Chemical SiOg ?e203 AI2O3 Ti02 MaO CaO HgO Loss <105 C. > 105 C.
43.80^ 1.69 1.97 0 .12 0.08
24.94 7.10 4.52
1 15.19 99.42
Petrographic
Most of the m a te ria l c o n s is ts of c la y lik nas3Q3 which give a d e f in i t e x -ray p attern not unlike a hydrous calcium aili oats The q u a rts content i s ior?r (probabi less than 1 per c e n t). About 5 per cent of o aleito is present *
Approximately 15-20 per cant of the mate: is c h ry so tils or serpentine, which is la: iy fibrous* The f ib e r s and bundles pres are u su a lly se v e ra l m illim e te rs long and seldom s h o rte r than 0=3 m illim eter*
Chemical 3i02 P e 23 A1 23 ifciO CaO 5ig0
H ag0
k2o
H20
AEALTSES OF LG7G--FIBE3, A3BSST05
(as received)
Petrographic
38.40# 5.32 0.78 0.08
The m a te ria l contains about 75 per cent \
fibrous asbestos, probably ch ry eo tile, w seme serp en tin e and s n a il amounts of cal:
raagnotits and c h l c r i t i c or micaceous mio a l s . Only a tra c e of q u a rts was seen. ! wars shreds of non-separated f ib e r s 10 t 50 microns long and 5 to 15 microns wida
0.31
40.18
0 .0 6
0.06
0.57
14.00 85*76
CM
00