Document JrgrjYqR4ax0QoE6xXvnB4aQe

To: Colmer, Robert W SC-DCS/18 <Rob.Colmer@shell.com> From: Clegg, Patsy M SCC-DCS/22 </O=SHE LUOU=MSXSCC/CN=RE CI PI ENTS/CN=PH197432> Cc: Bcc: Received Date: 2007-04-1813:47:45 GMT Subject: FW: Shanghai Health Study Update -----Original Message----- From: Clegg, Patsy M SCC-DCS/22 Sent: Tuesday, April 17, 20079:41 AM To: Methvin, Stacy P SCC-DCA; Williams, Charlie CR SIEP-EPT-RL; Simpson, Edward J SCC-DCA/2 Cc: Snyder, Phil J SDIUS-DXX/9; Sykes, Paul B SCC-DCS/23; Williams, Elizabeth J SCAI-DCS/22; Cagen, Stuart Z SHLOIL-SHOIL-SHS; Tsai, Shan P SHLOIL-SHS; Semmler, Klaus K DSC-DCS/235 Subject: Shanghai Health Study Update Progress is being made towards establishing a new contract with CinPathogen and extending the University of Colorado grant to support finishing the Shanghai Health Study. Key issues include providing advance funding to keep the lab operating while new contracts are being established and developing specific deliverables and timelines for the new contract and grant. All sponsors have executed contract amendment 4 agreeing to additional funding. Timeline for the study: case accrual will continue beyond 08) June 30 07 December 31 07 2008 December 31 08 End AML case accrual End lymphoid neoplasms (formerly NHL) Data analysis and publications (some publications Study ends; consortium disbands Key events are listed below. April 11 : API Executive Committee reached consensus on (1) supporting the advance of $800K to Dr. Irons providing that he agrees to certain terms. No additional funds until contract is in place. Attached is the letter that Red Cavaney sent to Dr. Irons. (2) funding through CinPathogen conditional on all API contract criteria being met. The draft list of action items from the meeting: April 16: Dr. Irons signed letter. API wired $800K to CinPathogen. Irons isgned letter on April 12; IT challenges in transmitting to API. Consortium conference call to further develop list of deliverables to support items in IronslAPlletter. API has discussed with Irons, so understanding and agreement can be more quickly achieved. April 26 Consortium call scheduled to finalize deliverables and get up update on API contracting criteria being met. I will keep you updated. Happy to address any questions or comments. Patsy Clegg SH ELL-MCCLU RG-060475 Product Steward Shell Chemical LP One Shell Plaza, 91 0 Louisiana, Houston, TX 77002-4916 Tel: +1 713241 2521 Fax: 3325 Email: patsy.clegg@shell.com Internet: http://www.shell.com/chemicals Attachments: 41107_RCLettertoRI rons. pdf Action Items - draft.ZIP SH ELL-MCCLU RG-060476