Document JN01m376V0qGkn20j3bjDxK0a
Gom m ittee of the Prog ressta htair (Dye Industry
R o o m 510-11, 60 E ast 42n d St r e e t N e w Y o r k ,N e w Y o r k 10017
M em bers
C o m b e Ch e m ic a l , In c . White P la in s , N.Y.
E s s e x Ch e m ic a l C r p . Clifton, N.J.
H e s s H a i r Mi l k L a b s . St. P a u l, Minn.
Ho o d s Ha ir P r o d u c t s , In c . Madrid, la.
L a s e r L a b o r a t o r ie s M inneapolis, Minn.
Ma j e s t i c Dr u g C o . New York, N.Y.
P e a r s o n P h a r m a c a l Co . Miami, Fla.
Su n Ra y Co m pa n y Bronx, New York
May 2 0 , 1970
R o b e rt A. K ehoe, M.D. U niversity of C in cin n ati K etterin g L aboratory Eden and B ethesda Avenues C in c in n a ti, Ohio 45219
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Dear D r. Kehoe:
A few m onths ag o we le a r n e d t h a t th e D iv is io n o f C o lo rs a n d C o s m e tic s o f t h e FDA w as c o n s i d e r i n g t h e s p o n s o r s h i p of an o f f ic ia l re se a rc h p ro je c t to determ ine independently th e p o ssib le ab so rp tio n of lead through th e use of lead a c e ta te h a i r c o lo r in g . T his in fo rm a tio n came to us t h r o u g h M r. D av id M i l l e r , whom y o u may rem em ber a s a s s o c i a t e d w i t h t h e FDA b u t now r e t i r e d a n d a c t i n g a s o u r co n su ltan t.
The e n c lo s u re s w i l l f a m ilia r iz e you 'w ith developm ents and w i l l b rin g you u p - to - d a te a s o f Mr. M i l l e r ' s l e t t e r o f May 1 1 th .
M r. I v a n Combe an d I f e e l t h a t t h e i d e a e x p r e s s e d i n t h e l a s t p a r a g r a p h o f M r. M i l l e r ' s l e t t e r o f May 1 1 th i s a good one and we w ould l i k e t o s e t up a m e e tin g w ith D r. M a r z u l l i a n d Mr* J o n e s a t w h ic h y o u c o u ld b e p r e s e n t . The f o l l o w i n g d a t e s w o u ld b e s a t i s f a c t o r y t o M r. Combe a n d t o me b u t w o u ld h a v e t o b e c o n fir m e d w i t h D r. M a r z u l l i and Mr. J o n e s: June 1 - 11 - 12 - 15 - 16 - 1 ? .
I sin c e rely hope th a t you w ill fin d i t p o ssib le to attend a m eeting on one o f th e s e d a te s and would a p p re c ia te h e a r in g from you a s to w hich d a te would be m ost c o n v en ien t f o r you.
W ith k in d e s t p e rs o n a l r e g a r d s ,
C ordially yours,
^COMMUTES /OF THE PROGRESSIVE i r /py ^ I n d u s t r y
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Mr. Ivan D. C o m b e , C h a i r m a n Combe Chemical, Inc. 180 Mamaroneck Ave White Plains, N . Y . 1 0 6 0 1
Dear Ivan: .
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< ^ have t o d a y t a l k e d t o M r . j e h n J o n e s . D i r e c t o r s ' < f t h e Division of C o l o r s and C o s m e t i c s a n d Db*. F a ra n c is s M a r z u l l i Chief of t h e D e r m a l T o x i c i t y B r a n c h o f t h e D * v : s i c : s o f Fh&irm ecology and T o x i c o l o g y , a b o u t l e a d h a i r d y e s . Th e s s e n c e o f these c o n v e r s a t i o n s i s
^ * D r . M a r z u l l i h a s o n e s o m e in v i t r o p e n e t r a t i o n studies o f l e a d h a i r d y e s u s i n g h u m a n s k i n s e c t i o n s results a r e o n l y p r e l i m i n a r y a n d i n d i c a t e t h a t l o a d
have a r e l a t i v e l y low speed o f p e n e t r a t i o n
would not make a d e f i n i t e s t a t e m e n t of t h e r e s u l t s t h u s f a r .
2 . D r . Ma i c h b a t h h a s n o t - s t a r t e d is s t i l l under contract.
' ^ M a r z u k l i s a i d t h e c o n t e m p l a t e d w o r k b y b<oth him
a n d D r . M a i b a c h d o e s n o t i n d i c a t e a m i s t r u s t o f iDr* K e h o e tS
; . w o r k b u t r a t h e r t h a t t h e y w is lh e d t a ex'tencB i t . ;Dr M ^ z u l l i i .
s a i d -h ey ho p ed , by u se o f a r a d i o a c t i v e |e a d t* -acer
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n i q u e , t o d e t e r m i n e i f l e a d i s stored m -ffie feodu .
- f o r m a t io n i s n o t o b t a i n a b l e from hi
4 . ; D r. M a rz u lli and M r. Jo n es wi i 1 be g lad to
you a n d o t h e r m em bers o f th e C o m m it te e a n d / o r D r . Keho to -
d i s c u s s F D A ' s s t u d i e s a t a n y t i m e c o n v e n i e n t t o voi. D r
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M a rz u lli said, a phone c a l l to him fo r an appointm ent w i l l ne
q u i t e s a t i s f a c t o r y . H i s p h o n e n u m b e r i s A x e a 202' 9 6 ,1 - 4 3 8 5
cc. Mr. Jule Gordon