Document JJO18Xzmbz75RVqY6gvvawVJa

/ t*' / SM-32 (REV. 5-78) ( Shell Oil Company Interoffice Memorandum OCTOBER 20, 1980 o\-:vU pvc_-^T>C' <=A -FROM: C. E. ROSS, D.O., F.A.C.Pr.M. TO: MR. R. H. COE SUBJECT: OSHA CANDIDATE CARCINOGEN LIST The Imperial Chemical Industries Limited Plastics Division Liver Angiosarcoma Cases has been reviewed by the Corporate Medical Department. The information is complete through May 1, 1980. The enclosed graph references this data, and reveals that the peak incidence of deaths from angiosarcoma of the liver occurred in approximately 1976 and has been on the decline since that year. The Chemical Manufacturers Association VCM brain tumor data is only complete through 1972, and is therefore inconclusive for use in Shell's response. It is concluded that the projected epidemic-like incidence of angiosarcoma of the liver in humans has not occurred, and that the observed cases of angiosarcoma in humans today is the result of unfortunate massive exposures in the past. Enclosure cc - Mr. R. W. Fortenbach C. E. Ross*, D.O., F.A.C.Pr.M, Associate Corporate Medical Director, Epidemiology see 1-1129 ANNUAL IN C ID E N C E OF AN' )SARCOMA O f THE L IV E R CASI . /BY GEOGRAPHICAL AREA (D ate o f D eath) see 1-1130 N o rth A m e rica ` ------------------- * W o r ld T o t a l s 1 0 -2 0 -8 0